Amino acid dipepetide frequency for Pseudomonas phage vB_PaeP_C2-10_Ab22

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.751AlaAla: 7.751 ± 1.677
0.861AlaCys: 0.861 ± 0.294
4.163AlaAsp: 4.163 ± 0.564
6.029AlaGlu: 6.029 ± 0.958
3.086AlaPhe: 3.086 ± 0.434
6.818AlaGly: 6.818 ± 1.244
1.148AlaHis: 1.148 ± 0.299
4.593AlaIle: 4.593 ± 0.693
5.239AlaLys: 5.239 ± 0.602
7.249AlaLeu: 7.249 ± 0.776
3.086AlaMet: 3.086 ± 0.48
3.732AlaAsn: 3.732 ± 0.506
3.517AlaPro: 3.517 ± 0.63
4.737AlaGln: 4.737 ± 1.063
3.23AlaArg: 3.23 ± 0.533
5.455AlaSer: 5.455 ± 0.675
3.445AlaThr: 3.445 ± 0.602
6.388AlaVal: 6.388 ± 0.965
1.005AlaTrp: 1.005 ± 0.283
2.656AlaTyr: 2.656 ± 0.53
0.0AlaXaa: 0.0 ± 0.0
Cys
0.861CysAla: 0.861 ± 0.299
0.215CysCys: 0.215 ± 0.117
0.646CysAsp: 0.646 ± 0.271
1.005CysGlu: 1.005 ± 0.225
0.287CysPhe: 0.287 ± 0.154
0.933CysGly: 0.933 ± 0.314
0.502CysHis: 0.502 ± 0.177
0.646CysIle: 0.646 ± 0.261
0.287CysLys: 0.287 ± 0.14
0.359CysLeu: 0.359 ± 0.145
0.287CysMet: 0.287 ± 0.153
0.646CysAsn: 0.646 ± 0.204
0.359CysPro: 0.359 ± 0.144
0.287CysGln: 0.287 ± 0.146
0.359CysArg: 0.359 ± 0.166
0.789CysSer: 0.789 ± 0.265
0.502CysThr: 0.502 ± 0.169
0.502CysVal: 0.502 ± 0.238
0.359CysTrp: 0.359 ± 0.194
0.287CysTyr: 0.287 ± 0.149
0.0CysXaa: 0.0 ± 0.0
Asp
5.024AspAla: 5.024 ± 0.562
0.502AspCys: 0.502 ± 0.209
2.943AspAsp: 2.943 ± 0.451
3.804AspGlu: 3.804 ± 0.756
2.153AspPhe: 2.153 ± 0.416
4.88AspGly: 4.88 ± 0.659
1.579AspHis: 1.579 ± 0.42
3.373AspIle: 3.373 ± 0.392
2.799AspLys: 2.799 ± 0.483
6.388AspLeu: 6.388 ± 0.688
1.579AspMet: 1.579 ± 0.291
2.297AspAsn: 2.297 ± 0.427
3.589AspPro: 3.589 ± 0.494
1.723AspGln: 1.723 ± 0.352
3.302AspArg: 3.302 ± 0.493
3.589AspSer: 3.589 ± 0.596
3.445AspThr: 3.445 ± 0.63
2.799AspVal: 2.799 ± 0.442
1.651AspTrp: 1.651 ± 0.291
1.723AspTyr: 1.723 ± 0.339
0.0AspXaa: 0.0 ± 0.0
Glu
6.675GluAla: 6.675 ± 0.977
0.861GluCys: 0.861 ± 0.236
4.593GluAsp: 4.593 ± 0.568
6.675GluGlu: 6.675 ± 1.27
2.153GluPhe: 2.153 ± 0.362
5.383GluGly: 5.383 ± 0.669
1.292GluHis: 1.292 ± 0.317
3.804GluIle: 3.804 ± 0.505
3.445GluLys: 3.445 ± 0.552
6.962GluLeu: 6.962 ± 0.849
2.297GluMet: 2.297 ± 0.461
2.512GluAsn: 2.512 ± 0.338
1.866GluPro: 1.866 ± 0.33
2.799GluGln: 2.799 ± 0.557
4.952GluArg: 4.952 ± 0.618
3.014GluSer: 3.014 ± 0.525
3.373GluThr: 3.373 ± 0.494
6.172GluVal: 6.172 ± 0.798
0.861GluTrp: 0.861 ± 0.235
2.225GluTyr: 2.225 ± 0.446
0.0GluXaa: 0.0 ± 0.0
Phe
1.866PheAla: 1.866 ± 0.41
0.359PheCys: 0.359 ± 0.179
2.081PheAsp: 2.081 ± 0.359
2.01PheGlu: 2.01 ± 0.404
1.22PhePhe: 1.22 ± 0.418
4.235PheGly: 4.235 ± 0.492
0.646PheHis: 0.646 ± 0.203
2.727PheIle: 2.727 ± 0.468
1.866PheLys: 1.866 ± 0.367
4.019PheLeu: 4.019 ± 0.523
1.148PheMet: 1.148 ± 0.259
1.866PheAsn: 1.866 ± 0.335
1.794PhePro: 1.794 ± 0.443
1.651PheGln: 1.651 ± 0.348
1.723PheArg: 1.723 ± 0.478
2.512PheSer: 2.512 ± 0.328
2.081PheThr: 2.081 ± 0.382
2.44PheVal: 2.44 ± 0.364
1.077PheTrp: 1.077 ± 0.328
1.22PheTyr: 1.22 ± 0.323
0.0PheXaa: 0.0 ± 0.0
Gly
7.105GlyAla: 7.105 ± 1.234
0.933GlyCys: 0.933 ± 0.245
5.239GlyAsp: 5.239 ± 0.545
4.88GlyGlu: 4.88 ± 0.537
3.014GlyPhe: 3.014 ± 0.618
6.89GlyGly: 6.89 ± 1.096
1.938GlyHis: 1.938 ± 0.385
4.378GlyIle: 4.378 ± 0.535
5.239GlyLys: 5.239 ± 0.732
5.383GlyLeu: 5.383 ± 0.537
2.153GlyMet: 2.153 ± 0.302
3.804GlyAsn: 3.804 ± 0.579
2.799GlyPro: 2.799 ± 0.464
3.014GlyGln: 3.014 ± 0.424
4.522GlyArg: 4.522 ± 0.606
6.029GlySer: 6.029 ± 0.852
5.239GlyThr: 5.239 ± 0.889
6.172GlyVal: 6.172 ± 0.578
1.22GlyTrp: 1.22 ± 0.294
2.512GlyTyr: 2.512 ± 0.376
0.0GlyXaa: 0.0 ± 0.0
His
1.507HisAla: 1.507 ± 0.41
0.431HisCys: 0.431 ± 0.179
0.789HisAsp: 0.789 ± 0.257
1.435HisGlu: 1.435 ± 0.429
1.148HisPhe: 1.148 ± 0.261
1.507HisGly: 1.507 ± 0.374
0.287HisHis: 0.287 ± 0.138
1.22HisIle: 1.22 ± 0.355
1.077HisLys: 1.077 ± 0.248
2.584HisLeu: 2.584 ± 0.526
0.502HisMet: 0.502 ± 0.211
0.718HisAsn: 0.718 ± 0.246
0.861HisPro: 0.861 ± 0.213
0.574HisGln: 0.574 ± 0.212
1.507HisArg: 1.507 ± 0.364
0.718HisSer: 0.718 ± 0.205
0.718HisThr: 0.718 ± 0.231
1.077HisVal: 1.077 ± 0.289
0.502HisTrp: 0.502 ± 0.244
0.574HisTyr: 0.574 ± 0.246
0.0HisXaa: 0.0 ± 0.0
Ile
4.091IleAla: 4.091 ± 0.539
0.718IleCys: 0.718 ± 0.225
2.727IleAsp: 2.727 ± 0.533
3.086IleGlu: 3.086 ± 0.464
2.153IlePhe: 2.153 ± 0.403
4.665IleGly: 4.665 ± 0.514
1.148IleHis: 1.148 ± 0.338
2.584IleIle: 2.584 ± 0.365
3.517IleLys: 3.517 ± 0.596
3.732IleLeu: 3.732 ± 0.549
1.077IleMet: 1.077 ± 0.334
2.153IleAsn: 2.153 ± 0.39
3.589IlePro: 3.589 ± 0.707
2.368IleGln: 2.368 ± 0.411
3.66IleArg: 3.66 ± 0.616
2.44IleSer: 2.44 ± 0.414
2.512IleThr: 2.512 ± 0.435
2.799IleVal: 2.799 ± 0.424
0.718IleTrp: 0.718 ± 0.217
2.01IleTyr: 2.01 ± 0.289
0.0IleXaa: 0.0 ± 0.0
Lys
4.665LysAla: 4.665 ± 0.699
0.359LysCys: 0.359 ± 0.16
3.732LysAsp: 3.732 ± 0.563
4.091LysGlu: 4.091 ± 0.47
2.297LysPhe: 2.297 ± 0.4
3.876LysGly: 3.876 ± 0.59
1.435LysHis: 1.435 ± 0.306
3.158LysIle: 3.158 ± 0.382
3.66LysLys: 3.66 ± 0.562
4.593LysLeu: 4.593 ± 0.592
1.077LysMet: 1.077 ± 0.286
1.938LysAsn: 1.938 ± 0.387
2.297LysPro: 2.297 ± 0.4
1.723LysGln: 1.723 ± 0.362
3.947LysArg: 3.947 ± 0.591
3.373LysSer: 3.373 ± 0.422
3.014LysThr: 3.014 ± 0.46
4.522LysVal: 4.522 ± 0.593
1.723LysTrp: 1.723 ± 0.38
2.584LysTyr: 2.584 ± 0.416
0.0LysXaa: 0.0 ± 0.0
Leu
7.034LeuAla: 7.034 ± 0.628
0.789LeuCys: 0.789 ± 0.215
5.67LeuAsp: 5.67 ± 0.601
6.531LeuGlu: 6.531 ± 0.75
2.943LeuPhe: 2.943 ± 0.443
7.034LeuGly: 7.034 ± 0.973
1.148LeuHis: 1.148 ± 0.32
2.943LeuIle: 2.943 ± 0.424
5.742LeuLys: 5.742 ± 0.606
6.747LeuLeu: 6.747 ± 0.692
2.01LeuMet: 2.01 ± 0.478
3.23LeuAsn: 3.23 ± 0.46
3.23LeuPro: 3.23 ± 0.533
3.732LeuGln: 3.732 ± 0.636
6.316LeuArg: 6.316 ± 0.602
4.306LeuSer: 4.306 ± 0.68
3.732LeuThr: 3.732 ± 0.428
5.239LeuVal: 5.239 ± 0.548
0.861LeuTrp: 0.861 ± 0.331
2.297LeuTyr: 2.297 ± 0.477
0.0LeuXaa: 0.0 ± 0.0
Met
3.014MetAla: 3.014 ± 0.548
0.215MetCys: 0.215 ± 0.127
1.651MetAsp: 1.651 ± 0.346
1.364MetGlu: 1.364 ± 0.299
1.148MetPhe: 1.148 ± 0.252
2.297MetGly: 2.297 ± 0.455
0.287MetHis: 0.287 ± 0.126
1.292MetIle: 1.292 ± 0.293
1.794MetLys: 1.794 ± 0.342
1.723MetLeu: 1.723 ± 0.347
0.718MetMet: 0.718 ± 0.192
1.148MetAsn: 1.148 ± 0.276
1.148MetPro: 1.148 ± 0.254
1.22MetGln: 1.22 ± 0.285
1.435MetArg: 1.435 ± 0.324
2.297MetSer: 2.297 ± 0.434
1.723MetThr: 1.723 ± 0.351
1.651MetVal: 1.651 ± 0.364
0.502MetTrp: 0.502 ± 0.164
0.646MetTyr: 0.646 ± 0.188
0.0MetXaa: 0.0 ± 0.0
Asn
3.804AsnAla: 3.804 ± 0.525
0.574AsnCys: 0.574 ± 0.189
2.368AsnAsp: 2.368 ± 0.374
3.23AsnGlu: 3.23 ± 0.451
1.579AsnPhe: 1.579 ± 0.355
3.373AsnGly: 3.373 ± 0.581
1.22AsnHis: 1.22 ± 0.291
2.656AsnIle: 2.656 ± 0.482
1.651AsnLys: 1.651 ± 0.337
2.943AsnLeu: 2.943 ± 0.436
1.148AsnMet: 1.148 ± 0.318
1.651AsnAsn: 1.651 ± 0.381
2.871AsnPro: 2.871 ± 0.445
2.153AsnGln: 2.153 ± 0.489
2.943AsnArg: 2.943 ± 0.34
1.866AsnSer: 1.866 ± 0.364
2.727AsnThr: 2.727 ± 0.506
2.584AsnVal: 2.584 ± 0.497
0.861AsnTrp: 0.861 ± 0.214
1.364AsnTyr: 1.364 ± 0.292
0.0AsnXaa: 0.0 ± 0.0
Pro
3.66ProAla: 3.66 ± 0.522
0.359ProCys: 0.359 ± 0.155
2.943ProAsp: 2.943 ± 0.463
4.952ProGlu: 4.952 ± 0.73
2.44ProPhe: 2.44 ± 0.433
3.445ProGly: 3.445 ± 0.533
0.718ProHis: 0.718 ± 0.256
1.866ProIle: 1.866 ± 0.351
2.871ProLys: 2.871 ± 0.452
2.297ProLeu: 2.297 ± 0.357
0.718ProMet: 0.718 ± 0.202
2.081ProAsn: 2.081 ± 0.417
1.579ProPro: 1.579 ± 0.539
2.081ProGln: 2.081 ± 0.42
1.651ProArg: 1.651 ± 0.389
1.651ProSer: 1.651 ± 0.311
2.727ProThr: 2.727 ± 0.412
2.368ProVal: 2.368 ± 0.467
0.574ProTrp: 0.574 ± 0.175
1.651ProTyr: 1.651 ± 0.397
0.0ProXaa: 0.0 ± 0.0
Gln
5.096GlnAla: 5.096 ± 0.772
0.287GlnCys: 0.287 ± 0.151
2.225GlnAsp: 2.225 ± 0.438
3.014GlnGlu: 3.014 ± 0.487
1.148GlnPhe: 1.148 ± 0.281
2.943GlnGly: 2.943 ± 0.601
0.359GlnHis: 0.359 ± 0.137
1.651GlnIle: 1.651 ± 0.331
1.579GlnLys: 1.579 ± 0.344
3.158GlnLeu: 3.158 ± 0.517
2.081GlnMet: 2.081 ± 0.37
1.938GlnAsn: 1.938 ± 0.431
0.718GlnPro: 0.718 ± 0.222
2.368GlnGln: 2.368 ± 0.442
3.302GlnArg: 3.302 ± 0.469
2.153GlnSer: 2.153 ± 0.372
2.01GlnThr: 2.01 ± 0.39
3.589GlnVal: 3.589 ± 0.514
0.646GlnTrp: 0.646 ± 0.238
1.005GlnTyr: 1.005 ± 0.306
0.0GlnXaa: 0.0 ± 0.0
Arg
4.88ArgAla: 4.88 ± 0.724
0.502ArgCys: 0.502 ± 0.209
3.445ArgAsp: 3.445 ± 0.556
3.589ArgGlu: 3.589 ± 0.661
2.153ArgPhe: 2.153 ± 0.477
4.522ArgGly: 4.522 ± 0.534
1.22ArgHis: 1.22 ± 0.279
3.445ArgIle: 3.445 ± 0.408
3.66ArgLys: 3.66 ± 0.637
5.526ArgLeu: 5.526 ± 0.618
2.153ArgMet: 2.153 ± 0.402
3.302ArgAsn: 3.302 ± 0.481
1.938ArgPro: 1.938 ± 0.401
2.584ArgGln: 2.584 ± 0.399
3.876ArgArg: 3.876 ± 0.647
3.66ArgSer: 3.66 ± 0.593
2.081ArgThr: 2.081 ± 0.381
4.88ArgVal: 4.88 ± 0.659
0.718ArgTrp: 0.718 ± 0.231
1.435ArgTyr: 1.435 ± 0.351
0.0ArgXaa: 0.0 ± 0.0
Ser
4.378SerAla: 4.378 ± 0.666
0.718SerCys: 0.718 ± 0.207
3.086SerAsp: 3.086 ± 0.453
4.737SerGlu: 4.737 ± 0.61
2.225SerPhe: 2.225 ± 0.581
5.742SerGly: 5.742 ± 0.466
1.077SerHis: 1.077 ± 0.258
3.517SerIle: 3.517 ± 0.473
3.589SerLys: 3.589 ± 0.547
3.947SerLeu: 3.947 ± 0.672
1.435SerMet: 1.435 ± 0.328
2.297SerAsn: 2.297 ± 0.391
2.368SerPro: 2.368 ± 0.454
2.368SerGln: 2.368 ± 0.445
2.871SerArg: 2.871 ± 0.461
3.732SerSer: 3.732 ± 0.565
2.153SerThr: 2.153 ± 0.436
4.091SerVal: 4.091 ± 0.579
1.579SerTrp: 1.579 ± 0.412
2.01SerTyr: 2.01 ± 0.503
0.0SerXaa: 0.0 ± 0.0
Thr
4.593ThrAla: 4.593 ± 0.558
0.287ThrCys: 0.287 ± 0.165
2.225ThrAsp: 2.225 ± 0.461
3.23ThrGlu: 3.23 ± 0.399
2.368ThrPhe: 2.368 ± 0.484
4.593ThrGly: 4.593 ± 0.681
1.364ThrHis: 1.364 ± 0.298
2.727ThrIle: 2.727 ± 0.543
2.44ThrLys: 2.44 ± 0.454
4.88ThrLeu: 4.88 ± 0.601
1.077ThrMet: 1.077 ± 0.244
2.081ThrAsn: 2.081 ± 0.333
3.947ThrPro: 3.947 ± 0.649
2.225ThrGln: 2.225 ± 0.341
2.656ThrArg: 2.656 ± 0.422
2.727ThrSer: 2.727 ± 0.58
2.799ThrThr: 2.799 ± 0.576
3.876ThrVal: 3.876 ± 0.534
0.574ThrTrp: 0.574 ± 0.259
1.005ThrTyr: 1.005 ± 0.28
0.0ThrXaa: 0.0 ± 0.0
Val
4.952ValAla: 4.952 ± 0.567
0.502ValCys: 0.502 ± 0.18
4.665ValAsp: 4.665 ± 0.516
4.88ValGlu: 4.88 ± 0.571
3.086ValPhe: 3.086 ± 0.462
5.383ValGly: 5.383 ± 0.551
1.651ValHis: 1.651 ± 0.392
2.584ValIle: 2.584 ± 0.417
3.876ValLys: 3.876 ± 0.319
5.168ValLeu: 5.168 ± 0.636
1.651ValMet: 1.651 ± 0.308
3.876ValAsn: 3.876 ± 0.402
2.01ValPro: 2.01 ± 0.355
2.225ValGln: 2.225 ± 0.373
4.45ValArg: 4.45 ± 0.517
4.593ValSer: 4.593 ± 0.49
4.737ValThr: 4.737 ± 0.67
5.311ValVal: 5.311 ± 0.73
0.933ValTrp: 0.933 ± 0.267
3.014ValTyr: 3.014 ± 0.436
0.0ValXaa: 0.0 ± 0.0
Trp
1.364TrpAla: 1.364 ± 0.291
0.215TrpCys: 0.215 ± 0.116
1.22TrpAsp: 1.22 ± 0.276
1.435TrpGlu: 1.435 ± 0.367
0.574TrpPhe: 0.574 ± 0.19
1.435TrpGly: 1.435 ± 0.347
0.0TrpHis: 0.0 ± 0.0
0.646TrpIle: 0.646 ± 0.267
2.081TrpLys: 2.081 ± 0.421
1.22TrpLeu: 1.22 ± 0.271
0.574TrpMet: 0.574 ± 0.187
0.646TrpAsn: 0.646 ± 0.216
0.574TrpPro: 0.574 ± 0.267
0.359TrpGln: 0.359 ± 0.145
0.861TrpArg: 0.861 ± 0.237
1.077TrpSer: 1.077 ± 0.385
1.077TrpThr: 1.077 ± 0.254
0.718TrpVal: 0.718 ± 0.2
0.359TrpTrp: 0.359 ± 0.177
0.574TrpTyr: 0.574 ± 0.229
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.866TyrAla: 1.866 ± 0.33
0.431TyrCys: 0.431 ± 0.172
2.727TyrAsp: 2.727 ± 0.352
1.938TyrGlu: 1.938 ± 0.361
1.364TyrPhe: 1.364 ± 0.316
2.512TyrGly: 2.512 ± 0.375
0.718TyrHis: 0.718 ± 0.245
1.938TyrIle: 1.938 ± 0.412
1.723TyrLys: 1.723 ± 0.347
2.656TyrLeu: 2.656 ± 0.423
0.431TyrMet: 0.431 ± 0.191
1.651TyrAsn: 1.651 ± 0.307
1.579TyrPro: 1.579 ± 0.291
1.077TyrGln: 1.077 ± 0.256
2.01TyrArg: 2.01 ± 0.315
1.938TyrSer: 1.938 ± 0.44
1.579TyrThr: 1.579 ± 0.348
2.368TyrVal: 2.368 ± 0.442
0.287TyrTrp: 0.287 ± 0.181
1.292TyrTyr: 1.292 ± 0.399
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 71 proteins (13934 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski