Amino acid dipepetide frequency for Beihai picorna-like virus 19

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.26AlaAla: 6.26 ± 1.869
0.782AlaCys: 0.782 ± 0.873
2.347AlaAsp: 2.347 ± 0.722
5.086AlaGlu: 5.086 ± 1.914
4.304AlaPhe: 4.304 ± 1.008
7.042AlaGly: 7.042 ± 0.363
1.174AlaHis: 1.174 ± 1.31
1.956AlaIle: 1.956 ± 0.347
6.26AlaLys: 6.26 ± 0.661
4.304AlaLeu: 4.304 ± 1.008
1.565AlaMet: 1.565 ± 0.151
2.739AlaAsn: 2.739 ± 0.106
4.304AlaPro: 4.304 ± 0.376
1.565AlaGln: 1.565 ± 0.151
4.304AlaArg: 4.304 ± 0.89
4.304AlaSer: 4.304 ± 1.008
6.651AlaThr: 6.651 ± 1.731
8.216AlaVal: 8.216 ± 1.583
1.174AlaTrp: 1.174 ± 0.678
4.304AlaTyr: 4.304 ± 0.257
0.0AlaXaa: 0.0 ± 0.0
Cys
1.174CysAla: 1.174 ± 0.588
0.391CysCys: 0.391 ± 0.196
0.782CysAsp: 0.782 ± 0.392
0.391CysGlu: 0.391 ± 0.196
0.391CysPhe: 0.391 ± 0.196
1.565CysGly: 1.565 ± 0.784
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.782CysLys: 0.782 ± 0.392
0.391CysLeu: 0.391 ± 0.196
1.565CysMet: 1.565 ± 0.151
0.391CysAsn: 0.391 ± 0.196
1.174CysPro: 1.174 ± 0.045
0.0CysGln: 0.0 ± 0.0
0.391CysArg: 0.391 ± 0.437
0.391CysSer: 0.391 ± 0.196
1.956CysThr: 1.956 ± 0.918
0.782CysVal: 0.782 ± 0.392
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.304AspAla: 4.304 ± 1.008
1.174AspCys: 1.174 ± 0.588
2.739AspAsp: 2.739 ± 0.739
3.912AspGlu: 3.912 ± 0.061
0.782AspPhe: 0.782 ± 0.241
2.347AspGly: 2.347 ± 0.543
0.782AspHis: 0.782 ± 0.392
3.521AspIle: 3.521 ± 1.13
2.739AspLys: 2.739 ± 0.739
3.912AspLeu: 3.912 ± 0.694
0.782AspMet: 0.782 ± 0.669
1.565AspAsn: 1.565 ± 1.114
2.739AspPro: 2.739 ± 0.527
1.956AspGln: 1.956 ± 0.286
1.565AspArg: 1.565 ± 0.784
4.304AspSer: 4.304 ± 1.522
5.477AspThr: 5.477 ± 2.318
2.739AspVal: 2.739 ± 0.527
0.782AspTrp: 0.782 ± 0.392
1.565AspTyr: 1.565 ± 0.151
0.0AspXaa: 0.0 ± 0.0
Glu
3.13GluAla: 3.13 ± 0.302
1.174GluCys: 1.174 ± 0.588
4.695GluAsp: 4.695 ± 0.453
3.521GluGlu: 3.521 ± 0.498
4.304GluPhe: 4.304 ± 0.376
2.739GluGly: 2.739 ± 1.159
1.174GluHis: 1.174 ± 0.678
2.347GluIle: 2.347 ± 0.722
2.347GluLys: 2.347 ± 1.175
7.433GluLeu: 7.433 ± 0.074
1.565GluMet: 1.565 ± 0.151
3.521GluAsn: 3.521 ± 1.13
3.521GluPro: 3.521 ± 1.4
2.347GluGln: 2.347 ± 0.09
1.174GluArg: 1.174 ± 0.588
2.739GluSer: 2.739 ± 0.739
2.739GluThr: 2.739 ± 0.739
3.912GluVal: 3.912 ± 0.694
1.956GluTrp: 1.956 ± 0.286
3.521GluTyr: 3.521 ± 0.498
0.0GluXaa: 0.0 ± 0.0
Phe
6.26PheAla: 6.26 ± 0.029
0.391PheCys: 0.391 ± 0.437
1.956PheAsp: 1.956 ± 0.347
1.956PheGlu: 1.956 ± 1.551
2.347PhePhe: 2.347 ± 1.355
2.347PheGly: 2.347 ± 1.355
0.782PheHis: 0.782 ± 0.241
1.565PheIle: 1.565 ± 0.482
3.521PheLys: 3.521 ± 1.13
2.739PheLeu: 2.739 ± 1.371
1.956PheMet: 1.956 ± 0.98
2.347PheAsn: 2.347 ± 1.355
1.565PhePro: 1.565 ± 0.482
1.956PheGln: 1.956 ± 0.347
5.477PheArg: 5.477 ± 1.053
1.565PheSer: 1.565 ± 0.482
3.13PheThr: 3.13 ± 0.331
2.347PheVal: 2.347 ± 1.175
0.782PheTrp: 0.782 ± 0.241
2.347PheTyr: 2.347 ± 0.722
0.0PheXaa: 0.0 ± 0.0
Gly
1.956GlyAla: 1.956 ± 0.286
1.174GlyCys: 1.174 ± 0.588
3.912GlyAsp: 3.912 ± 0.571
6.651GlyGlu: 6.651 ± 2.996
3.521GlyPhe: 3.521 ± 1.4
4.304GlyGly: 4.304 ± 1.641
0.782GlyHis: 0.782 ± 0.392
2.739GlyIle: 2.739 ± 1.371
4.695GlyLys: 4.695 ± 0.18
4.304GlyLeu: 4.304 ± 0.257
1.956GlyMet: 1.956 ± 0.347
1.174GlyAsn: 1.174 ± 0.045
2.347GlyPro: 2.347 ± 0.722
1.956GlyGln: 1.956 ± 0.347
3.13GlyArg: 3.13 ± 0.935
5.086GlySer: 5.086 ± 0.016
3.912GlyThr: 3.912 ± 1.204
5.086GlyVal: 5.086 ± 0.016
1.174GlyTrp: 1.174 ± 0.045
0.782GlyTyr: 0.782 ± 0.392
0.0GlyXaa: 0.0 ± 0.0
His
1.174HisAla: 1.174 ± 0.045
0.782HisCys: 0.782 ± 0.241
1.174HisAsp: 1.174 ± 0.045
1.174HisGlu: 1.174 ± 0.588
0.782HisPhe: 0.782 ± 0.873
0.391HisGly: 0.391 ± 0.196
0.391HisHis: 0.391 ± 0.196
0.782HisIle: 0.782 ± 0.873
0.782HisLys: 0.782 ± 0.241
3.13HisLeu: 3.13 ± 0.935
0.391HisMet: 0.391 ± 0.196
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.782HisGln: 0.782 ± 0.873
0.782HisArg: 0.782 ± 0.241
1.174HisSer: 1.174 ± 1.31
2.347HisThr: 2.347 ± 1.175
0.782HisVal: 0.782 ± 0.873
0.782HisTrp: 0.782 ± 0.392
0.391HisTyr: 0.391 ± 0.196
0.0HisXaa: 0.0 ± 0.0
Ile
6.651IleAla: 6.651 ± 0.465
0.0IleCys: 0.0 ± 0.0
3.13IleAsp: 3.13 ± 0.935
2.739IleGlu: 2.739 ± 0.106
2.739IlePhe: 2.739 ± 0.106
2.739IleGly: 2.739 ± 0.106
0.391IleHis: 0.391 ± 0.196
2.347IleIle: 2.347 ± 0.09
1.174IleLys: 1.174 ± 0.588
1.956IleLeu: 1.956 ± 0.286
1.956IleMet: 1.956 ± 0.286
3.521IleAsn: 3.521 ± 0.135
4.304IlePro: 4.304 ± 0.257
1.956IleGln: 1.956 ± 0.347
1.565IleArg: 1.565 ± 1.114
4.695IleSer: 4.695 ± 0.18
3.13IleThr: 3.13 ± 0.935
1.956IleVal: 1.956 ± 0.918
0.782IleTrp: 0.782 ± 0.392
0.782IleTyr: 0.782 ± 0.241
0.0IleXaa: 0.0 ± 0.0
Lys
6.26LysAla: 6.26 ± 2.502
1.174LysCys: 1.174 ± 0.588
3.912LysAsp: 3.912 ± 1.959
3.521LysGlu: 3.521 ± 0.498
3.521LysPhe: 3.521 ± 1.13
2.347LysGly: 2.347 ± 1.175
0.782LysHis: 0.782 ± 0.241
1.174LysIle: 1.174 ± 0.588
1.956LysLys: 1.956 ± 0.347
6.26LysLeu: 6.26 ± 0.029
1.565LysMet: 1.565 ± 0.151
1.956LysAsn: 1.956 ± 0.286
5.086LysPro: 5.086 ± 0.016
0.391LysGln: 0.391 ± 0.196
6.651LysArg: 6.651 ± 0.8
3.13LysSer: 3.13 ± 1.567
0.391LysThr: 0.391 ± 0.196
2.739LysVal: 2.739 ± 0.527
0.782LysTrp: 0.782 ± 0.392
1.174LysTyr: 1.174 ± 0.588
0.0LysXaa: 0.0 ± 0.0
Leu
7.433LeuAla: 7.433 ± 1.972
0.782LeuCys: 0.782 ± 0.392
4.304LeuAsp: 4.304 ± 1.008
4.304LeuGlu: 4.304 ± 0.257
1.956LeuPhe: 1.956 ± 0.347
4.695LeuGly: 4.695 ± 0.812
1.565LeuHis: 1.565 ± 0.482
2.739LeuIle: 2.739 ± 0.106
3.912LeuLys: 3.912 ± 1.326
6.651LeuLeu: 6.651 ± 2.065
1.174LeuMet: 1.174 ± 0.699
4.304LeuAsn: 4.304 ± 0.89
3.912LeuPro: 3.912 ± 0.061
3.13LeuGln: 3.13 ± 0.331
5.477LeuArg: 5.477 ± 0.212
5.869LeuSer: 5.869 ± 0.225
5.869LeuThr: 5.869 ± 0.408
3.912LeuVal: 3.912 ± 1.959
0.391LeuTrp: 0.391 ± 0.196
2.347LeuTyr: 2.347 ± 0.543
0.0LeuXaa: 0.0 ± 0.0
Met
1.956MetAla: 1.956 ± 0.347
0.391MetCys: 0.391 ± 0.196
2.347MetAsp: 2.347 ± 0.543
1.956MetGlu: 1.956 ± 0.98
1.565MetPhe: 1.565 ± 0.482
1.174MetGly: 1.174 ± 0.045
1.174MetHis: 1.174 ± 0.588
1.565MetIle: 1.565 ± 0.784
2.739MetLys: 2.739 ± 1.371
1.956MetLeu: 1.956 ± 0.347
0.782MetMet: 0.782 ± 0.392
1.174MetAsn: 1.174 ± 0.588
2.739MetPro: 2.739 ± 0.106
1.174MetGln: 1.174 ± 0.678
1.565MetArg: 1.565 ± 0.151
2.347MetSer: 2.347 ± 0.09
1.174MetThr: 1.174 ± 0.588
3.13MetVal: 3.13 ± 0.302
1.174MetTrp: 1.174 ± 0.588
0.782MetTyr: 0.782 ± 0.241
0.0MetXaa: 0.0 ± 0.0
Asn
2.347AsnAla: 2.347 ± 0.722
0.391AsnCys: 0.391 ± 0.196
1.565AsnAsp: 1.565 ± 0.151
2.347AsnGlu: 2.347 ± 0.09
1.174AsnPhe: 1.174 ± 0.588
2.347AsnGly: 2.347 ± 0.09
0.782AsnHis: 0.782 ± 0.241
2.739AsnIle: 2.739 ± 0.106
1.565AsnLys: 1.565 ± 0.151
3.13AsnLeu: 3.13 ± 0.302
2.347AsnMet: 2.347 ± 0.543
2.347AsnAsn: 2.347 ± 1.175
2.739AsnPro: 2.739 ± 0.106
1.956AsnGln: 1.956 ± 0.286
2.347AsnArg: 2.347 ± 0.722
4.695AsnSer: 4.695 ± 0.453
2.347AsnThr: 2.347 ± 1.355
3.521AsnVal: 3.521 ± 0.135
1.174AsnTrp: 1.174 ± 0.045
2.739AsnTyr: 2.739 ± 0.527
0.0AsnXaa: 0.0 ± 0.0
Pro
3.912ProAla: 3.912 ± 0.694
0.0ProCys: 0.0 ± 0.0
2.739ProAsp: 2.739 ± 0.527
5.086ProGlu: 5.086 ± 0.016
1.565ProPhe: 1.565 ± 1.114
3.912ProGly: 3.912 ± 0.061
0.782ProHis: 0.782 ± 0.873
1.565ProIle: 1.565 ± 0.151
3.521ProLys: 3.521 ± 1.13
4.695ProLeu: 4.695 ± 0.812
2.347ProMet: 2.347 ± 0.722
2.347ProAsn: 2.347 ± 0.09
3.912ProPro: 3.912 ± 1.326
3.912ProGln: 3.912 ± 0.571
4.304ProArg: 4.304 ± 0.376
4.304ProSer: 4.304 ± 1.522
3.912ProThr: 3.912 ± 0.061
5.869ProVal: 5.869 ± 2.123
1.565ProTrp: 1.565 ± 1.747
1.956ProTyr: 1.956 ± 0.286
0.0ProXaa: 0.0 ± 0.0
Gln
1.956GlnAla: 1.956 ± 0.286
0.782GlnCys: 0.782 ± 0.392
1.174GlnAsp: 1.174 ± 0.045
3.521GlnGlu: 3.521 ± 0.135
2.347GlnPhe: 2.347 ± 0.543
3.912GlnGly: 3.912 ± 1.204
0.0GlnHis: 0.0 ± 0.0
0.391GlnIle: 0.391 ± 0.437
3.912GlnLys: 3.912 ± 0.694
4.695GlnLeu: 4.695 ± 1.445
0.391GlnMet: 0.391 ± 0.196
1.565GlnAsn: 1.565 ± 0.482
1.956GlnPro: 1.956 ± 0.918
1.174GlnGln: 1.174 ± 0.678
1.174GlnArg: 1.174 ± 0.678
1.565GlnSer: 1.565 ± 0.482
1.956GlnThr: 1.956 ± 0.286
3.13GlnVal: 3.13 ± 0.302
1.565GlnTrp: 1.565 ± 0.151
0.782GlnTyr: 0.782 ± 0.392
0.0GlnXaa: 0.0 ± 0.0
Arg
2.347ArgAla: 2.347 ± 1.355
0.782ArgCys: 0.782 ± 0.392
2.739ArgAsp: 2.739 ± 0.106
3.13ArgGlu: 3.13 ± 0.935
2.739ArgPhe: 2.739 ± 0.106
3.13ArgGly: 3.13 ± 1.596
1.174ArgHis: 1.174 ± 0.588
3.521ArgIle: 3.521 ± 0.767
2.347ArgLys: 2.347 ± 0.09
4.695ArgLeu: 4.695 ± 0.18
1.956ArgMet: 1.956 ± 0.98
2.739ArgAsn: 2.739 ± 0.106
3.912ArgPro: 3.912 ± 0.571
1.956ArgGln: 1.956 ± 0.918
5.869ArgArg: 5.869 ± 1.041
5.086ArgSer: 5.086 ± 1.281
3.521ArgThr: 3.521 ± 0.767
4.304ArgVal: 4.304 ± 1.522
0.391ArgTrp: 0.391 ± 0.196
2.347ArgTyr: 2.347 ± 1.355
0.0ArgXaa: 0.0 ± 0.0
Ser
5.869SerAla: 5.869 ± 1.041
0.391SerCys: 0.391 ± 0.196
1.956SerAsp: 1.956 ± 0.347
2.739SerGlu: 2.739 ± 1.371
3.912SerPhe: 3.912 ± 1.204
3.912SerGly: 3.912 ± 0.694
1.565SerHis: 1.565 ± 0.784
6.26SerIle: 6.26 ± 0.661
4.695SerLys: 4.695 ± 1.086
4.695SerLeu: 4.695 ± 1.086
1.956SerMet: 1.956 ± 0.98
3.13SerAsn: 3.13 ± 0.331
4.695SerPro: 4.695 ± 1.445
3.521SerGln: 3.521 ± 0.498
2.739SerArg: 2.739 ± 0.527
3.521SerSer: 3.521 ± 1.4
5.086SerThr: 5.086 ± 0.616
2.739SerVal: 2.739 ± 0.106
1.565SerTrp: 1.565 ± 0.784
1.565SerTyr: 1.565 ± 1.114
0.0SerXaa: 0.0 ± 0.0
Thr
3.912ThrAla: 3.912 ± 1.837
1.174ThrCys: 1.174 ± 0.045
3.13ThrAsp: 3.13 ± 1.596
1.956ThrGlu: 1.956 ± 0.347
4.304ThrPhe: 4.304 ± 0.376
4.695ThrGly: 4.695 ± 1.445
1.174ThrHis: 1.174 ± 0.045
5.869ThrIle: 5.869 ± 1.49
1.956ThrLys: 1.956 ± 0.347
2.739ThrLeu: 2.739 ± 0.106
1.956ThrMet: 1.956 ± 0.347
4.304ThrAsn: 4.304 ± 2.273
8.216ThrPro: 8.216 ± 0.318
2.739ThrGln: 2.739 ± 0.106
1.956ThrArg: 1.956 ± 0.98
3.912ThrSer: 3.912 ± 0.571
7.433ThrThr: 7.433 ± 1.972
5.086ThrVal: 5.086 ± 1.882
1.565ThrTrp: 1.565 ± 0.482
2.347ThrTyr: 2.347 ± 0.543
0.0ThrXaa: 0.0 ± 0.0
Val
5.869ValAla: 5.869 ± 0.857
0.391ValCys: 0.391 ± 0.437
2.739ValAsp: 2.739 ± 0.106
2.739ValGlu: 2.739 ± 0.527
1.565ValPhe: 1.565 ± 0.151
4.304ValGly: 4.304 ± 0.89
2.347ValHis: 2.347 ± 0.09
5.086ValIle: 5.086 ± 0.649
3.521ValLys: 3.521 ± 1.763
3.521ValLeu: 3.521 ± 1.13
3.521ValMet: 3.521 ± 0.498
3.912ValAsn: 3.912 ± 0.694
3.521ValPro: 3.521 ± 0.135
2.739ValGln: 2.739 ± 0.527
4.695ValArg: 4.695 ± 0.18
3.13ValSer: 3.13 ± 0.302
5.477ValThr: 5.477 ± 2.318
3.521ValVal: 3.521 ± 1.13
0.0ValTrp: 0.0 ± 0.0
3.521ValTyr: 3.521 ± 0.498
0.0ValXaa: 0.0 ± 0.0
Trp
0.782TrpAla: 0.782 ± 0.241
0.0TrpCys: 0.0 ± 0.0
1.565TrpAsp: 1.565 ± 0.482
1.565TrpGlu: 1.565 ± 0.151
0.391TrpPhe: 0.391 ± 0.196
0.0TrpGly: 0.0 ± 0.0
0.782TrpHis: 0.782 ± 0.241
1.174TrpIle: 1.174 ± 0.588
1.174TrpLys: 1.174 ± 0.588
2.347TrpLeu: 2.347 ± 0.722
0.391TrpMet: 0.391 ± 0.196
0.391TrpAsn: 0.391 ± 0.196
0.391TrpPro: 0.391 ± 0.196
1.174TrpGln: 1.174 ± 0.678
1.565TrpArg: 1.565 ± 1.114
1.956TrpSer: 1.956 ± 0.347
0.391TrpThr: 0.391 ± 0.437
0.782TrpVal: 0.782 ± 0.392
0.782TrpTrp: 0.782 ± 0.392
1.956TrpTyr: 1.956 ± 0.347
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.086TyrAla: 5.086 ± 0.016
0.391TyrCys: 0.391 ± 0.196
0.782TyrAsp: 0.782 ± 0.241
1.565TyrGlu: 1.565 ± 0.151
3.13TyrPhe: 3.13 ± 0.302
2.739TyrGly: 2.739 ± 0.106
0.391TyrHis: 0.391 ± 0.437
1.174TyrIle: 1.174 ± 0.045
1.174TyrLys: 1.174 ± 0.045
1.565TyrLeu: 1.565 ± 0.784
2.347TyrMet: 2.347 ± 1.175
1.174TyrAsn: 1.174 ± 0.588
1.174TyrPro: 1.174 ± 0.045
1.565TyrGln: 1.565 ± 0.482
1.956TyrArg: 1.956 ± 0.286
2.739TyrSer: 2.739 ± 0.527
3.521TyrThr: 3.521 ± 0.767
1.565TyrVal: 1.565 ± 0.151
1.174TyrTrp: 1.174 ± 0.678
1.174TyrTyr: 1.174 ± 0.045
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2557 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski