Human coronavirus HKU1 (HCoV-HKU1)
Average proteome isoelectric point is 7.18
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A140H1H0|A0A140H1H0_CVHK1 Hemagglutinin-esterase OS=Human coronavirus HKU1 OX=290028 GN=HE PE=3 SV=1
MM1 pKa = 7.7 IKK3 pKa = 9.44 TSKK6 pKa = 10.62 YY7 pKa = 10.03 GLGFKK12 pKa = 9.08 WAPEE16 pKa = 3.94 FRR18 pKa = 11.84 WLLPDD23 pKa = 3.72 AAEE26 pKa = 4.24 EE27 pKa = 4.02 LASPMKK33 pKa = 10.38 SDD35 pKa = 4.3 EE36 pKa = 4.65 GGLCPSTGQAMEE48 pKa = 4.39 SVGFVYY54 pKa = 10.57 DD55 pKa = 3.35 NHH57 pKa = 6.8 VKK59 pKa = 9.92 IDD61 pKa = 3.64 CRR63 pKa = 11.84 CILGQEE69 pKa = 3.81 WHH71 pKa = 6.2 VQSNLIRR78 pKa = 11.84 DD79 pKa = 3.97 IFVHH83 pKa = 6.51 EE84 pKa = 4.79 DD85 pKa = 3.2 LHH87 pKa = 7.67 VVEE90 pKa = 5.45 VLTKK94 pKa = 9.2 TAVKK98 pKa = 10.25 SGTAILIKK106 pKa = 10.71 SPLHH110 pKa = 5.74 SLGGFPKK117 pKa = 10.21 GYY119 pKa = 10.96 VMGLFRR125 pKa = 11.84 SYY127 pKa = 8.78 KK128 pKa = 6.84 TKK130 pKa = 10.36 RR131 pKa = 11.84 YY132 pKa = 8.66 VVHH135 pKa = 6.6 HH136 pKa = 6.68 LSMTTSTTNFGEE148 pKa = 5.21 DD149 pKa = 3.38 FLGWIVPFGFMPSYY163 pKa = 7.96 VHH165 pKa = 6.99 KK166 pKa = 10.12 WFQFCRR172 pKa = 11.84 LYY174 pKa = 10.45 IEE176 pKa = 4.67 EE177 pKa = 4.51 SDD179 pKa = 5.23 LIISNFKK186 pKa = 10.5 FDD188 pKa = 5.53 DD189 pKa = 3.65 YY190 pKa = 11.82 DD191 pKa = 4.54 FSVEE195 pKa = 3.61 DD196 pKa = 4.43 AYY198 pKa = 11.03 AEE200 pKa = 4.02 VHH202 pKa = 6.43 AEE204 pKa = 3.99 PKK206 pKa = 10.54 GKK208 pKa = 10.39 YY209 pKa = 7.17 SQKK212 pKa = 10.9 AYY214 pKa = 10.83 ALLRR218 pKa = 11.84 QYY220 pKa = 11.08 RR221 pKa = 11.84 GIKK224 pKa = 9.3 PVLFVDD230 pKa = 5.3 QYY232 pKa = 10.87 GCDD235 pKa = 3.8 YY236 pKa = 10.79 SGKK239 pKa = 10.3 LADD242 pKa = 4.22 CLQAYY247 pKa = 7.96 GHH249 pKa = 6.54 YY250 pKa = 9.97 SLQDD254 pKa = 3.24 MRR256 pKa = 11.84 QKK258 pKa = 10.75 QSVWLANCDD267 pKa = 3.38 FDD269 pKa = 5.92 IVVAWHH275 pKa = 5.52 VVRR278 pKa = 11.84 DD279 pKa = 3.61 SRR281 pKa = 11.84 FVMRR285 pKa = 11.84 LQTIATICGIKK296 pKa = 10.33 YY297 pKa = 8.91 VAQPTEE303 pKa = 4.1 DD304 pKa = 3.76 VVDD307 pKa = 3.92 GDD309 pKa = 4.02 VVIRR313 pKa = 11.84 EE314 pKa = 4.21 PVHH317 pKa = 6.51 LLSADD322 pKa = 4.03 AIVLKK327 pKa = 10.56 LPSLMKK333 pKa = 10.88 VMTHH337 pKa = 6.19 MDD339 pKa = 3.62 DD340 pKa = 4.77 FSIKK344 pKa = 10.32 SIYY347 pKa = 10.45 NVDD350 pKa = 3.59 LCDD353 pKa = 4.05 CGFVMQYY360 pKa = 11.2 GYY362 pKa = 11.34 VDD364 pKa = 4.33 CFNDD368 pKa = 3.11 NCDD371 pKa = 3.45 FYY373 pKa = 11.7 GWVSGNMMDD382 pKa = 5.33 GFSCPLCCTVYY393 pKa = 10.83 DD394 pKa = 3.91 SSEE397 pKa = 3.97 VKK399 pKa = 10.3 AQSSGVIPEE408 pKa = 4.09 NPVLFTNSTDD418 pKa = 3.79 TVNHH422 pKa = 7.06 DD423 pKa = 3.41 SFNLYY428 pKa = 10.02 GYY430 pKa = 10.18 SVTPFGSCIYY440 pKa = 9.5 WSPRR444 pKa = 11.84 PGLWIPIIKK453 pKa = 10.3 SSVKK457 pKa = 10.59 SYY459 pKa = 11.66 DD460 pKa = 3.36 DD461 pKa = 3.65 LVYY464 pKa = 11.0 SGVVGCKK471 pKa = 10.3 SIVKK475 pKa = 7.85 EE476 pKa = 3.99 TALITHH482 pKa = 7.51 ALYY485 pKa = 10.83 LDD487 pKa = 4.05 YY488 pKa = 11.09 VQCKK492 pKa = 9.97 CGNLEE497 pKa = 3.91 QNHH500 pKa = 6.16 ILGVNNSWCRR510 pKa = 11.84 QLLLNRR516 pKa = 11.84 GDD518 pKa = 3.96 YY519 pKa = 11.61 NMLLKK524 pKa = 11.02 NIDD527 pKa = 3.8 LFVKK531 pKa = 10.36 RR532 pKa = 11.84 RR533 pKa = 11.84 ADD535 pKa = 3.91 FACKK539 pKa = 9.7 FAVCGDD545 pKa = 3.61 GFVPFLLDD553 pKa = 3.26 GLIPRR558 pKa = 11.84 SYY560 pKa = 11.48 YY561 pKa = 10.55 LIQSGIFFTSLMSQFSQEE579 pKa = 4.01 VSDD582 pKa = 4.64 MCLKK586 pKa = 9.96 MCILFMDD593 pKa = 4.55 RR594 pKa = 11.84 VSVATFYY601 pKa = 10.69 IEE603 pKa = 5.1 HH604 pKa = 5.78 YY605 pKa = 10.18 VNRR608 pKa = 11.84 LVTQFKK614 pKa = 10.95 LLGTTLVNKK623 pKa = 8.19 MVNWFNTMLDD633 pKa = 3.3 ASAPATGWLLYY644 pKa = 10.49 QLLNGLFVVSQANFNFVALIPDD666 pKa = 3.59 YY667 pKa = 11.59 AKK669 pKa = 10.5 ILVDD673 pKa = 3.68 KK674 pKa = 10.31 FYY676 pKa = 10.92 TFFKK680 pKa = 10.96 LLLEE684 pKa = 4.46 CVTVDD689 pKa = 3.36 VLKK692 pKa = 11.05 DD693 pKa = 3.42 MPVLKK698 pKa = 9.68 TINGLVCIVGNKK710 pKa = 9.35 FYY712 pKa = 10.85 NVSIGLIPGFVLPCNAQEE730 pKa = 3.78 QQIYY734 pKa = 9.38 FFEE737 pKa = 4.9 GVAEE741 pKa = 4.17 SVIVEE746 pKa = 4.26 DD747 pKa = 5.77 DD748 pKa = 3.68 VIEE751 pKa = 4.13 NVKK754 pKa = 10.67 SSLSSYY760 pKa = 9.54 EE761 pKa = 3.63 YY762 pKa = 10.22 CQPPKK767 pKa = 10.43 SVEE770 pKa = 4.12 KK771 pKa = 10.58 ICIIDD776 pKa = 3.53 NMYY779 pKa = 9.82 MGKK782 pKa = 10.27 CGDD785 pKa = 3.55 KK786 pKa = 10.59 FFPIVMNDD794 pKa = 3.22 KK795 pKa = 10.63 NICLLDD801 pKa = 3.6 QAWRR805 pKa = 11.84 FPCAGRR811 pKa = 11.84 KK812 pKa = 8.26 VNFNEE817 pKa = 4.19 KK818 pKa = 9.09 PVVMEE823 pKa = 4.51 IPSLMTVKK831 pKa = 10.67 VMFDD835 pKa = 3.53 LDD837 pKa = 3.88 STFDD841 pKa = 4.8 DD842 pKa = 3.95 ILGKK846 pKa = 10.17 VCSEE850 pKa = 4.2 FEE852 pKa = 4.15 VEE854 pKa = 5.16 KK855 pKa = 10.96 GVTVDD860 pKa = 4.24 DD861 pKa = 5.19 FVAVVCDD868 pKa = 4.53 AIEE871 pKa = 4.07 NALNSCKK878 pKa = 9.36 EE879 pKa = 4.11 HH880 pKa = 6.52 PVVGYY885 pKa = 7.05 QVRR888 pKa = 11.84 AFLNKK893 pKa = 9.76 LNEE896 pKa = 4.11 NVVYY900 pKa = 10.72 LFDD903 pKa = 3.96 EE904 pKa = 5.17 AGDD907 pKa = 3.53 EE908 pKa = 4.26 AMASRR913 pKa = 11.84 MYY915 pKa = 10.0 CTFAIEE921 pKa = 4.26 DD922 pKa = 3.88 VEE924 pKa = 4.81 DD925 pKa = 4.28 VISSEE930 pKa = 4.29 VVEE933 pKa = 4.18 DD934 pKa = 4.3 TIDD937 pKa = 3.68 GVVEE941 pKa = 3.76 DD942 pKa = 5.37 TINDD946 pKa = 3.82 DD947 pKa = 3.7 EE948 pKa = 5.48 DD949 pKa = 4.39 VVTGDD954 pKa = 4.26 NDD956 pKa = 4.08 DD957 pKa = 4.08 EE958 pKa = 5.02 DD959 pKa = 4.98 VVTGDD964 pKa = 4.26 NDD966 pKa = 4.08 DD967 pKa = 4.08 EE968 pKa = 5.02 DD969 pKa = 4.98 VVTGDD974 pKa = 4.26 NDD976 pKa = 4.08 DD977 pKa = 4.08 EE978 pKa = 5.02 DD979 pKa = 4.98 VVTGDD984 pKa = 4.26 NDD986 pKa = 4.08 DD987 pKa = 4.08 EE988 pKa = 5.02 DD989 pKa = 4.98 VVTGDD994 pKa = 4.26 NDD996 pKa = 4.08 DD997 pKa = 4.08 EE998 pKa = 5.02 DD999 pKa = 4.98 VVTGDD1004 pKa = 4.26 NDD1006 pKa = 4.08 DD1007 pKa = 4.08 EE1008 pKa = 5.02 DD1009 pKa = 4.98 VVTGDD1014 pKa = 4.26 NDD1016 pKa = 4.08 DD1017 pKa = 4.08 EE1018 pKa = 5.02 DD1019 pKa = 4.98 VVTGDD1024 pKa = 4.26 NDD1026 pKa = 4.08 DD1027 pKa = 4.08 EE1028 pKa = 5.02 DD1029 pKa = 4.98 VVTGDD1034 pKa = 4.26 NDD1036 pKa = 4.08 DD1037 pKa = 4.08 EE1038 pKa = 5.02 DD1039 pKa = 4.98 VVTGDD1044 pKa = 4.26 NDD1046 pKa = 4.08 DD1047 pKa = 4.08 EE1048 pKa = 5.02 DD1049 pKa = 4.98 VVTGDD1054 pKa = 4.26 NDD1056 pKa = 4.08 DD1057 pKa = 4.08 EE1058 pKa = 5.02 DD1059 pKa = 4.98 VVTGDD1064 pKa = 4.26 NDD1066 pKa = 4.08 DD1067 pKa = 4.08 EE1068 pKa = 5.02 DD1069 pKa = 4.98 VVTGDD1074 pKa = 4.82 NDD1076 pKa = 4.98 DD1077 pKa = 5.62 DD1078 pKa = 5.15 NDD1080 pKa = 3.93 DD1081 pKa = 4.04 QIVVIGDD1088 pKa = 3.74 DD1089 pKa = 3.67 VDD1091 pKa = 6.43 DD1092 pKa = 5.13 IDD1094 pKa = 5.18 TINCEE1099 pKa = 4.25 SIYY1102 pKa = 10.97 EE1103 pKa = 3.98 FDD1105 pKa = 3.43 TYY1107 pKa = 11.33 KK1108 pKa = 11.19 ALLVFNDD1115 pKa = 3.83 VYY1117 pKa = 11.61 NDD1119 pKa = 3.62 ALFVSYY1125 pKa = 10.53 GSSVEE1130 pKa = 3.94 TEE1132 pKa = 4.12 TYY1134 pKa = 10.63 FKK1136 pKa = 11.28 VKK1138 pKa = 10.29 GLWSPTITHH1147 pKa = 5.87 TNCWLRR1153 pKa = 11.84 SVLLVMQKK1161 pKa = 10.81 LPFKK1165 pKa = 10.74 FKK1167 pKa = 11.03 DD1168 pKa = 3.45 LAIEE1172 pKa = 4.13 NMWLSYY1178 pKa = 10.5 KK1179 pKa = 10.39 VGYY1182 pKa = 7.65 NQRR1185 pKa = 11.84 FVDD1188 pKa = 4.11 YY1189 pKa = 10.68 LLTTIPKK1196 pKa = 10.29 AIVLPQGGFVADD1208 pKa = 4.2 FAYY1211 pKa = 9.74 WFLNQFDD1218 pKa = 3.81 INAYY1222 pKa = 10.41 ANWCCLKK1229 pKa = 10.77 CGFSFDD1235 pKa = 5.4 LNGLDD1240 pKa = 4.39 AVFFYY1245 pKa = 11.39 GDD1247 pKa = 3.56 IVSHH1251 pKa = 5.36 VCKK1254 pKa = 10.3 CGYY1257 pKa = 11.01 NMTLIAADD1265 pKa = 4.8 LPCTLHH1271 pKa = 7.34 FSLFDD1276 pKa = 4.41 DD1277 pKa = 4.39 NFCAFCTPKK1286 pKa = 10.66 KK1287 pKa = 10.81 NFIAACAVDD1296 pKa = 4.47 VNVCHH1301 pKa = 6.18 SVAVIGDD1308 pKa = 3.63 EE1309 pKa = 4.13 QIDD1312 pKa = 3.9 GKK1314 pKa = 10.94 FVTKK1318 pKa = 10.33 FSGDD1322 pKa = 3.1 KK1323 pKa = 10.14 FDD1325 pKa = 6.19 FIVGYY1330 pKa = 10.78 GMSFSMSSFEE1340 pKa = 4.4 LAQLYY1345 pKa = 8.24 GLCITPNVCFVKK1357 pKa = 10.75 GDD1359 pKa = 4.01 IINVARR1365 pKa = 11.84 LVKK1368 pKa = 10.49 ADD1370 pKa = 4.02 VIVNPANGHH1379 pKa = 5.01 MLHH1382 pKa = 6.66 GGGVAKK1388 pKa = 10.67 AIAVAAGKK1396 pKa = 10.27 KK1397 pKa = 9.44 FSKK1400 pKa = 8.99 EE1401 pKa = 3.28 TAAMVKK1407 pKa = 10.24 SKK1409 pKa = 10.41 GVCQVGDD1416 pKa = 4.23 CYY1418 pKa = 11.49 VSTGGKK1424 pKa = 8.87 LCKK1427 pKa = 9.87 TILNIVGPDD1436 pKa = 3.08 ARR1438 pKa = 11.84 QDD1440 pKa = 3.31 GRR1442 pKa = 11.84 QSYY1445 pKa = 10.14 VLLARR1450 pKa = 11.84 AYY1452 pKa = 9.49 KK1453 pKa = 10.26 HH1454 pKa = 5.99 LNKK1457 pKa = 9.94 YY1458 pKa = 9.58 DD1459 pKa = 3.84 CCLSTLISAGIFSVPADD1476 pKa = 3.42 VSLTYY1481 pKa = 11.15 LLGVVDD1487 pKa = 4.0 KK1488 pKa = 11.05 QVILVSNNKK1497 pKa = 9.41 EE1498 pKa = 3.96 DD1499 pKa = 3.64 FDD1501 pKa = 6.16 IIQKK1505 pKa = 9.75 CQITSVVGTKK1515 pKa = 10.42 ALAVRR1520 pKa = 11.84 LTANVGRR1527 pKa = 11.84 VIKK1530 pKa = 10.78 FEE1532 pKa = 3.84 TDD1534 pKa = 2.67 AYY1536 pKa = 10.18 KK1537 pKa = 10.99 LFLSGDD1543 pKa = 3.69 DD1544 pKa = 4.03 CFVSNSSVIQEE1555 pKa = 4.2 VLLLRR1560 pKa = 11.84 HH1561 pKa = 7.14 DD1562 pKa = 3.52 IQLNNDD1568 pKa = 2.87 VRR1570 pKa = 11.84 DD1571 pKa = 3.83 YY1572 pKa = 11.15 LLSKK1576 pKa = 7.93 MTSLPKK1582 pKa = 10.15 DD1583 pKa = 2.82 WRR1585 pKa = 11.84 LINKK1589 pKa = 9.09 FDD1591 pKa = 3.98 VINGVKK1597 pKa = 7.68 TVKK1600 pKa = 10.58 YY1601 pKa = 8.76 FEE1603 pKa = 5.13 CPNSIYY1609 pKa = 10.27 ICSQGKK1615 pKa = 9.86 DD1616 pKa = 3.35 FGYY1619 pKa = 10.65 VCDD1622 pKa = 3.96 GSFYY1626 pKa = 10.78 KK1627 pKa = 10.34 ATVNQVCVLLAKK1639 pKa = 10.45 KK1640 pKa = 9.91 IDD1642 pKa = 3.56 VLLTVDD1648 pKa = 4.03 GVNFKK1653 pKa = 10.84 SISLTVGEE1661 pKa = 4.62 VFGKK1665 pKa = 10.25 ILGNVFCDD1673 pKa = 4.7 GIDD1676 pKa = 3.59 VTKK1679 pKa = 10.62 LKK1681 pKa = 11.02 CSDD1684 pKa = 4.39 FYY1686 pKa = 11.62 ADD1688 pKa = 4.39 KK1689 pKa = 10.8 ILYY1692 pKa = 9.69 QYY1694 pKa = 11.05 EE1695 pKa = 4.27 NLSLADD1701 pKa = 3.44 ISAVQSSFGFDD1712 pKa = 3.32 QQQLLAYY1719 pKa = 9.66 YY1720 pKa = 10.71 NFLTVCKK1727 pKa = 9.56 WSVVVNGPFFSFEE1740 pKa = 3.86 QSHH1743 pKa = 5.89 NNCYY1747 pKa = 10.96 VNVACLMLQHH1757 pKa = 6.92 INLKK1761 pKa = 9.01 FNKK1764 pKa = 8.83 WQWQEE1769 pKa = 2.87 AWYY1772 pKa = 9.49 EE1773 pKa = 4.07 FRR1775 pKa = 11.84 AGRR1778 pKa = 11.84 PHH1780 pKa = 7.21 RR1781 pKa = 11.84 LVALVLAKK1789 pKa = 10.57 GHH1791 pKa = 6.29 FKK1793 pKa = 10.62 FDD1795 pKa = 3.86 EE1796 pKa = 4.88 PSDD1799 pKa = 3.44 ATDD1802 pKa = 4.38 FIRR1805 pKa = 11.84 VVLKK1809 pKa = 10.69 QADD1812 pKa = 3.75 LSGAICEE1819 pKa = 4.8 LEE1821 pKa = 4.62 LICDD1825 pKa = 3.96 CGIKK1829 pKa = 9.84 QEE1831 pKa = 4.19 SRR1833 pKa = 11.84 VGVDD1837 pKa = 2.85 AVMHH1841 pKa = 6.59 FGTLAKK1847 pKa = 9.71 TDD1849 pKa = 3.95 LFNGYY1854 pKa = 10.1 KK1855 pKa = 9.8 IGCNCAGRR1863 pKa = 11.84 IVHH1866 pKa = 5.43 CTKK1869 pKa = 10.83 LNVPFLICSNTPLSKK1884 pKa = 10.65 DD1885 pKa = 3.47 LPDD1888 pKa = 4.48 DD1889 pKa = 3.72 VVAANMFMGVGVGHH1903 pKa = 5.44 YY1904 pKa = 7.77 THH1906 pKa = 7.41 LKK1908 pKa = 9.76 CGSPYY1913 pKa = 10.08 QHH1915 pKa = 6.89 YY1916 pKa = 9.27 DD1917 pKa = 2.71 ACSVKK1922 pKa = 10.37 KK1923 pKa = 7.88 YY1924 pKa = 9.23 TGVSGCLTDD1933 pKa = 5.47 CLYY1936 pKa = 11.21 LKK1938 pKa = 10.75 NLTQTFTSMLTNYY1951 pKa = 10.07 FLDD1954 pKa = 4.08 DD1955 pKa = 3.87 VEE1957 pKa = 4.53 MVAYY1961 pKa = 10.6 NPDD1964 pKa = 3.3 LSQYY1968 pKa = 9.96 YY1969 pKa = 9.81 CDD1971 pKa = 3.28 NGKK1974 pKa = 10.73 YY1975 pKa = 6.29 YY1976 pKa = 9.96 TKK1978 pKa = 10.37 PIIKK1982 pKa = 10.08 AQFKK1986 pKa = 10.37 PFAKK1990 pKa = 10.65 VNGVYY1995 pKa = 10.54 TNFKK1999 pKa = 10.63 LVGHH2003 pKa = 6.86 DD2004 pKa = 3.44 ICAQLNDD2011 pKa = 3.74 KK2012 pKa = 11.08 LGFNVDD2018 pKa = 3.96 LPFVEE2023 pKa = 4.87 YY2024 pKa = 10.39 KK2025 pKa = 8.95 VTVWPVATGDD2035 pKa = 3.69 VVLASDD2041 pKa = 3.72 DD2042 pKa = 4.86 LYY2044 pKa = 11.26 VKK2046 pKa = 10.22 RR2047 pKa = 11.84 YY2048 pKa = 9.36 FKK2050 pKa = 11.08 GCEE2053 pKa = 3.92 TFGKK2057 pKa = 9.01 PVIWFCHH2064 pKa = 6.54 DD2065 pKa = 3.44 EE2066 pKa = 4.14 ASLNSLTYY2074 pKa = 10.27 FNKK2077 pKa = 10.2 PSFKK2081 pKa = 10.65 SEE2083 pKa = 3.31 NRR2085 pKa = 11.84 YY2086 pKa = 10.04 SVLSVDD2092 pKa = 4.04 SVSEE2096 pKa = 3.93 EE2097 pKa = 3.99 SQGNVVTSVMEE2108 pKa = 4.16 SQISTKK2114 pKa = 7.34 EE2115 pKa = 3.87 VKK2117 pKa = 10.56 LKK2119 pKa = 10.67 GVRR2122 pKa = 11.84 KK2123 pKa = 7.14 TVKK2126 pKa = 9.95 IEE2128 pKa = 3.7 DD2129 pKa = 4.37 AIIVNDD2135 pKa = 3.83 EE2136 pKa = 3.83 NSSIKK2141 pKa = 10.09 VVKK2144 pKa = 10.35 SLSLVDD2150 pKa = 3.42 VWDD2153 pKa = 4.17 MYY2155 pKa = 10.96 LTGCDD2160 pKa = 3.45 YY2161 pKa = 11.11 VVWVANEE2168 pKa = 3.91 LSRR2171 pKa = 11.84 LVKK2174 pKa = 10.49 SPTVRR2179 pKa = 11.84 EE2180 pKa = 3.98 YY2181 pKa = 10.29 IRR2183 pKa = 11.84 YY2184 pKa = 8.41 GIKK2187 pKa = 10.44 PITIPIDD2194 pKa = 3.77 LLCLRR2199 pKa = 11.84 DD2200 pKa = 4.25 DD2201 pKa = 4.07 NQTLLVPKK2209 pKa = 9.87 IFKK2212 pKa = 10.32 ARR2214 pKa = 11.84 AIEE2217 pKa = 4.62 FYY2219 pKa = 11.32 GFLKK2223 pKa = 10.32 WLFIYY2228 pKa = 9.69 VFNLLHH2234 pKa = 5.77 FTNDD2238 pKa = 2.46 KK2239 pKa = 10.35 TIFYY2243 pKa = 6.71 TTEE2246 pKa = 3.55 IASKK2250 pKa = 8.81 FTFNLFCLALKK2261 pKa = 10.48 NAFQTFRR2268 pKa = 11.84 WSIFIKK2274 pKa = 10.54 GFLVVATVFLFWFNFLYY2291 pKa = 10.63 INVIFSDD2298 pKa = 5.0 FYY2300 pKa = 11.32 LPNISVFPIFVGRR2313 pKa = 11.84 IVMWIKK2319 pKa = 10.03 ATFGLVTICDD2329 pKa = 5.02 FYY2331 pKa = 11.91 SKK2333 pKa = 10.57 LGVGFTSHH2341 pKa = 6.91 FCNGSFICEE2350 pKa = 4.05 LCYY2353 pKa = 10.82 SGFDD2357 pKa = 3.64 MLDD2360 pKa = 2.98 TYY2362 pKa = 11.62 AAIDD2366 pKa = 3.74 FVQYY2370 pKa = 10.53 EE2371 pKa = 3.82 VDD2373 pKa = 3.39 RR2374 pKa = 11.84 RR2375 pKa = 11.84 VLFDD2379 pKa = 3.49 YY2380 pKa = 11.16 VSLVKK2385 pKa = 10.71 LIVEE2389 pKa = 4.01 LVIGYY2394 pKa = 9.1 SLYY2397 pKa = 10.39 TVWFYY2402 pKa = 10.99 PLFCLIGLQLFTTWLPDD2419 pKa = 3.39 LFMLEE2424 pKa = 4.09 TMHH2427 pKa = 6.41 WLIRR2431 pKa = 11.84 FIVFVANMLPAFVLLRR2447 pKa = 11.84 FYY2449 pKa = 10.81 IVVTAMYY2456 pKa = 9.58 KK2457 pKa = 8.86 VVGFIRR2463 pKa = 11.84 HH2464 pKa = 5.45 IVYY2467 pKa = 10.12 GCNKK2471 pKa = 9.78 AGCLFCYY2478 pKa = 9.99 KK2479 pKa = 9.81 RR2480 pKa = 11.84 NCSVRR2485 pKa = 11.84 VKK2487 pKa = 10.6 CSTIVGGVIRR2497 pKa = 11.84 YY2498 pKa = 9.43 YY2499 pKa = 10.83 DD2500 pKa = 3.15 ITANGGTGFCVKK2512 pKa = 10.39 HH2513 pKa = 5.21 QWNCFNCHH2521 pKa = 5.17 SFKK2524 pKa = 10.74 PGNTFITVEE2533 pKa = 3.89 AAIEE2537 pKa = 3.8 LSKK2540 pKa = 10.58 EE2541 pKa = 4.01 LKK2543 pKa = 10.53 RR2544 pKa = 11.84 PVNPTDD2550 pKa = 3.32 ASHH2553 pKa = 6.76 YY2554 pKa = 9.84 VVTDD2558 pKa = 3.63 IKK2560 pKa = 11.03 QVGCMMRR2567 pKa = 11.84 LFYY2570 pKa = 11.03 DD2571 pKa = 3.28 RR2572 pKa = 11.84 DD2573 pKa = 3.56 GQRR2576 pKa = 11.84 VYY2578 pKa = 11.71 DD2579 pKa = 4.98 DD2580 pKa = 3.62 VDD2582 pKa = 3.13 ASLFVDD2588 pKa = 4.32 INNLLHH2594 pKa = 6.79 SKK2596 pKa = 10.52 VKK2598 pKa = 10.25 VVPNLYY2604 pKa = 10.04 VVVVEE2609 pKa = 4.78 SDD2611 pKa = 2.95 ADD2613 pKa = 3.81 RR2614 pKa = 11.84 ANFLNAVVFYY2624 pKa = 10.31 AQSLYY2629 pKa = 10.87 RR2630 pKa = 11.84 PILLVDD2636 pKa = 3.84 KK2637 pKa = 10.96 KK2638 pKa = 11.19 LITTACNGISVTQTMFDD2655 pKa = 3.71 VYY2657 pKa = 11.26 VDD2659 pKa = 3.35 TFMSHH2664 pKa = 6.82 FDD2666 pKa = 3.37 VDD2668 pKa = 3.53 RR2669 pKa = 11.84 KK2670 pKa = 10.65 SFNNFVNIAHH2680 pKa = 6.91 ASLRR2684 pKa = 11.84 EE2685 pKa = 4.03 GVQLEE2690 pKa = 4.37 KK2691 pKa = 11.23 VLDD2694 pKa = 3.88 TFVGCVRR2701 pKa = 11.84 KK2702 pKa = 10.08 CCSIDD2707 pKa = 3.42 SDD2709 pKa = 4.19 VEE2711 pKa = 4.16 TRR2713 pKa = 11.84 FITKK2717 pKa = 10.55 SMISAVAAGLEE2728 pKa = 4.35 FTDD2731 pKa = 3.5 EE2732 pKa = 4.33 NYY2734 pKa = 11.18 NNLVPTYY2741 pKa = 9.6 LKK2743 pKa = 10.53 SDD2745 pKa = 4.07 NIVAADD2751 pKa = 4.4 LGVLIQNGAKK2761 pKa = 9.66 HH2762 pKa = 4.99 VQGNVAKK2769 pKa = 9.98 AANISCIWFIDD2780 pKa = 3.65 AFNQLTADD2788 pKa = 4.09 LQHH2791 pKa = 6.83 KK2792 pKa = 9.28 LKK2794 pKa = 10.24 KK2795 pKa = 10.35 ACVKK2799 pKa = 10.06 TGLKK2803 pKa = 10.41 LKK2805 pKa = 9.53 LTFNKK2810 pKa = 9.94 QEE2812 pKa = 3.78 ASVPILTTPFSLKK2825 pKa = 10.67 GGVVLSNLLYY2835 pKa = 10.18 ILFFISLICFILLWALLPTYY2855 pKa = 10.32 SVYY2858 pKa = 10.79 KK2859 pKa = 10.49 SDD2861 pKa = 3.01 IHH2863 pKa = 7.65 LPAYY2867 pKa = 10.45 ASFKK2871 pKa = 10.85 VIDD2874 pKa = 3.79 NGVVRR2879 pKa = 11.84 DD2880 pKa = 3.62 ISVNDD2885 pKa = 3.4 LCFANKK2891 pKa = 9.54 FFQFDD2896 pKa = 2.89 QWYY2899 pKa = 8.43 EE2900 pKa = 4.12 STFGSVYY2907 pKa = 9.67 YY2908 pKa = 9.83 HH2909 pKa = 6.9 NSMDD2913 pKa = 3.88 CPIVVAVMDD2922 pKa = 4.3 EE2923 pKa = 4.96 DD2924 pKa = 3.77 IGSTMFNVPTKK2935 pKa = 9.3 VLRR2938 pKa = 11.84 HH2939 pKa = 5.73 GFHH2942 pKa = 6.32 VLHH2945 pKa = 6.79 FLTYY2949 pKa = 10.73 AFASDD2954 pKa = 4.15 SVQCYY2959 pKa = 8.01 TPHH2962 pKa = 7.23 IQISYY2967 pKa = 9.16 NDD2969 pKa = 4.75 FYY2971 pKa = 11.89 ASGCVLSSLCTMFKK2985 pKa = 10.56 RR2986 pKa = 11.84 GDD2988 pKa = 3.94 GTPHH2992 pKa = 7.44 PYY2994 pKa = 10.07 CYY2996 pKa = 10.45 SDD2998 pKa = 3.93 GVMKK3002 pKa = 10.63 NASLYY3007 pKa = 9.58 TSLVPHH3013 pKa = 6.42 TRR3015 pKa = 11.84 YY3016 pKa = 10.58 SLANSNGFIRR3026 pKa = 11.84 FPDD3029 pKa = 4.05 VISEE3033 pKa = 4.48 GIVRR3037 pKa = 11.84 IVRR3040 pKa = 11.84 TRR3042 pKa = 11.84 SMTYY3046 pKa = 9.87 CRR3048 pKa = 11.84 VGACEE3053 pKa = 3.71 YY3054 pKa = 10.7 AEE3056 pKa = 4.46 EE3057 pKa = 5.22 GICFNFNSSWVLNNDD3072 pKa = 3.96 YY3073 pKa = 10.17 YY3074 pKa = 11.5 RR3075 pKa = 11.84 SMPGTFCGRR3084 pKa = 11.84 DD3085 pKa = 3.53 LFDD3088 pKa = 4.84 LFYY3091 pKa = 11.02 QFFSSLIRR3099 pKa = 11.84 PIDD3102 pKa = 3.85 FFSLTASSIFGAILAIVVVLVFYY3125 pKa = 9.95 YY3126 pKa = 10.75 LIKK3129 pKa = 10.55 LKK3131 pKa = 10.56 RR3132 pKa = 11.84 AFGDD3136 pKa = 3.56 YY3137 pKa = 10.38 TSVVVINVVVWCINFLMLFVFQVYY3161 pKa = 8.05 PICACVYY3168 pKa = 8.21 ACFYY3172 pKa = 10.61 FYY3174 pKa = 10.53 VTLYY3178 pKa = 9.72 FPSEE3182 pKa = 3.95 ISVIMHH3188 pKa = 6.39 LQWIVMYY3195 pKa = 10.03 GAIMPFWFCVTYY3207 pKa = 10.68 VAMVIANHH3215 pKa = 5.59 VLWLFSYY3222 pKa = 10.25 CRR3224 pKa = 11.84 KK3225 pKa = 10.0 IGVNVCSDD3233 pKa = 3.45 STFEE3237 pKa = 4.17 EE3238 pKa = 4.84 TSLTTFMITKK3248 pKa = 10.3 DD3249 pKa = 3.4 SYY3251 pKa = 11.58 CRR3253 pKa = 11.84 LKK3255 pKa = 11.29 NSVSDD3260 pKa = 3.68 VAYY3263 pKa = 10.77 NRR3265 pKa = 11.84 YY3266 pKa = 9.56 LSLYY3270 pKa = 9.16 NKK3272 pKa = 9.11 YY3273 pKa = 10.18 RR3274 pKa = 11.84 YY3275 pKa = 9.93 YY3276 pKa = 10.31 SGKK3279 pKa = 9.13 MDD3281 pKa = 3.55 TAAYY3285 pKa = 10.06 RR3286 pKa = 11.84 EE3287 pKa = 4.4 AACSQLAKK3295 pKa = 10.88 AMEE3298 pKa = 4.5 TFNHH3302 pKa = 6.06 NNGNDD3307 pKa = 3.53 VLYY3310 pKa = 10.33 QPPTASVSTSFLQSGIVKK3328 pKa = 9.04 MVSPTSKK3335 pKa = 9.99 IEE3337 pKa = 3.77 PCIVSVTYY3345 pKa = 11.08 GSMTLNGLWLDD3356 pKa = 3.9 DD3357 pKa = 3.69 KK3358 pKa = 10.97 VYY3360 pKa = 10.68 CPRR3363 pKa = 11.84 HH3364 pKa = 5.46 VICSSSNMNEE3374 pKa = 3.86 PDD3376 pKa = 3.7 YY3377 pKa = 11.37 SALLCRR3383 pKa = 11.84 VTLGDD3388 pKa = 3.55 FTIMSGRR3395 pKa = 11.84 MSLTVVSYY3403 pKa = 10.7 QMQGCQLVLTVSLQNPYY3420 pKa = 8.36 TPKK3423 pKa = 9.4 YY3424 pKa = 8.53 TFGNVKK3430 pKa = 9.92 PGEE3433 pKa = 4.41 TFTVLAAYY3441 pKa = 9.88 NGRR3444 pKa = 11.84 PQGAFHH3450 pKa = 5.55 VTMRR3454 pKa = 11.84 SSYY3457 pKa = 8.45 TIKK3460 pKa = 10.79 GSFLCGSCGSVGYY3473 pKa = 10.65 VLTGDD3478 pKa = 3.8 SVKK3481 pKa = 10.16 FVYY3484 pKa = 8.88 MHH3486 pKa = 6.09 QLEE3489 pKa = 4.95 LSTGCHH3495 pKa = 6.09 TGTDD3499 pKa = 4.13 FTGNFYY3505 pKa = 11.17 GPYY3508 pKa = 9.3 RR3509 pKa = 11.84 DD3510 pKa = 3.72 AQVVQLPVKK3519 pKa = 10.63 DD3520 pKa = 3.87 YY3521 pKa = 9.22 VQTVNVIAWLYY3532 pKa = 10.65 AAILNNCAWFVQNDD3546 pKa = 3.53 VCSTEE3551 pKa = 4.7 DD3552 pKa = 3.45 FNVWAMANGFSQVKK3566 pKa = 10.25 ADD3568 pKa = 4.09 LVLDD3572 pKa = 4.53 ALASMTGVSIEE3583 pKa = 4.23 TLLAAIKK3590 pKa = 9.66 RR3591 pKa = 11.84 LYY3593 pKa = 10.14 MGFQGRR3599 pKa = 11.84 QILGSCTFEE3608 pKa = 6.17 DD3609 pKa = 4.04 EE3610 pKa = 4.49 LAPSDD3615 pKa = 5.01 VYY3617 pKa = 11.1 QQLAGVKK3624 pKa = 9.33 LQSKK3628 pKa = 5.99 TKK3630 pKa = 10.31 RR3631 pKa = 11.84 FIKK3634 pKa = 9.18 EE3635 pKa = 3.63 TIYY3638 pKa = 10.33 WILISTFLFSCIISAFVKK3656 pKa = 8.39 WTIFMYY3662 pKa = 10.49 INTHH3666 pKa = 5.73 MIGVTLCVLCFVSFMMLLVKK3686 pKa = 10.44 HH3687 pKa = 5.38 KK3688 pKa = 10.23 HH3689 pKa = 6.09 FYY3691 pKa = 8.77 LTMYY3695 pKa = 9.83 IIPVLCTLFYY3705 pKa = 11.0 VNYY3708 pKa = 9.89 LVVYY3712 pKa = 10.25 KK3713 pKa = 10.6 EE3714 pKa = 3.93 GFRR3717 pKa = 11.84 GFTYY3721 pKa = 9.96 VWLSYY3726 pKa = 8.8 FVPAVNFTYY3735 pKa = 10.44 VYY3737 pKa = 10.02 EE3738 pKa = 4.14 VFYY3741 pKa = 11.31 GCILCVFAIFITMHH3755 pKa = 6.74 SINHH3759 pKa = 7.0 DD3760 pKa = 3.19 IFSLMFLVGRR3770 pKa = 11.84 IVTLISMWYY3779 pKa = 9.21 FGSNLEE3785 pKa = 3.96 EE3786 pKa = 4.45 DD3787 pKa = 3.81 VLLFITAFLGTYY3799 pKa = 7.26 TWTTILSLAIAKK3811 pKa = 9.52 IVANWLSVNIFYY3823 pKa = 8.38 FTDD3826 pKa = 3.15 VPYY3829 pKa = 10.58 IKK3831 pKa = 10.53 LILLSYY3837 pKa = 10.37 LFIGYY3842 pKa = 9.12 ILSCYY3847 pKa = 9.23 WGFFSLLNSVFRR3859 pKa = 11.84 MPMGVYY3865 pKa = 9.51 NYY3867 pKa = 9.72 KK3868 pKa = 10.25 ISVQEE3873 pKa = 3.84 LRR3875 pKa = 11.84 YY3876 pKa = 9.65 MNANGLRR3883 pKa = 11.84 PPRR3886 pKa = 11.84 NSFEE3890 pKa = 5.5 AILLNLKK3897 pKa = 10.18 LLGIGGVPVIEE3908 pKa = 4.37 VSQIQSKK3915 pKa = 8.33 LTDD3918 pKa = 3.41 VKK3920 pKa = 10.69 CANVVLLNCLQHH3932 pKa = 6.45 LHH3934 pKa = 5.73 VASNSKK3940 pKa = 9.38 LWQYY3944 pKa = 11.38 CSVLHH3949 pKa = 6.41 NEE3951 pKa = 4.3 ILSTSDD3957 pKa = 3.59 LSVAFDD3963 pKa = 4.38 KK3964 pKa = 10.96 LAQLLIVLFANPAAVDD3980 pKa = 4.15 TKK3982 pKa = 10.7 CLASIDD3988 pKa = 4.37 EE3989 pKa = 4.22 VSDD3992 pKa = 5.67 DD3993 pKa = 3.96 YY3994 pKa = 12.11 VQDD3997 pKa = 3.78 STVLQALQSEE4007 pKa = 4.91 FVNMASFVEE4016 pKa = 4.21 YY4017 pKa = 10.32 EE4018 pKa = 4.15 VAKK4021 pKa = 10.94 KK4022 pKa = 10.53 NLADD4026 pKa = 3.86 AKK4028 pKa = 11.01 NSGSVNQQQIKK4039 pKa = 9.54 QLEE4042 pKa = 4.38 KK4043 pKa = 9.98 ACNIAKK4049 pKa = 9.85 SVYY4052 pKa = 9.73 EE4053 pKa = 3.8 RR4054 pKa = 11.84 DD4055 pKa = 3.2 KK4056 pKa = 11.41 AVARR4060 pKa = 11.84 KK4061 pKa = 9.36 LEE4063 pKa = 4.05 RR4064 pKa = 11.84 MADD4067 pKa = 3.51 LALTNMYY4074 pKa = 10.38 KK4075 pKa = 10.21 EE4076 pKa = 4.51 ARR4078 pKa = 11.84 INDD4081 pKa = 3.85 KK4082 pKa = 10.59 KK4083 pKa = 11.18 SKK4085 pKa = 10.3 VVSALQTMLFSMVRR4099 pKa = 11.84 KK4100 pKa = 9.91 LDD4102 pKa = 3.65 NQALNSILDD4111 pKa = 3.81 NAVKK4115 pKa = 10.75 GCVPLSAIPALAANTLTIIIPDD4137 pKa = 3.46 KK4138 pKa = 10.83 QVFDD4142 pKa = 3.88 KK4143 pKa = 11.46 VVDD4146 pKa = 3.89 NVYY4149 pKa = 8.78 VTYY4152 pKa = 10.61 AGSVWHH4158 pKa = 6.52 IQTVQDD4164 pKa = 3.39 ADD4166 pKa = 4.5 GINKK4170 pKa = 9.06 QLTDD4174 pKa = 3.59 ISVDD4178 pKa = 4.01 SNWPLVIIANRR4189 pKa = 11.84 YY4190 pKa = 8.81 NEE4192 pKa = 3.97 VANAVMQNNEE4202 pKa = 4.3 LMPHH4206 pKa = 6.22 KK4207 pKa = 10.74 LKK4209 pKa = 10.69 IQVVNSGSDD4218 pKa = 3.41 MNCNIPTQCYY4228 pKa = 8.97 YY4229 pKa = 11.59 NNGSSGRR4236 pKa = 11.84 IVYY4239 pKa = 10.15 AVLSDD4244 pKa = 3.7 VDD4246 pKa = 3.57 GLKK4249 pKa = 9.05 YY4250 pKa = 9.21 TKK4252 pKa = 10.18 IMKK4255 pKa = 10.13 DD4256 pKa = 3.17 DD4257 pKa = 4.19 GNCVVLEE4264 pKa = 4.65 LDD4266 pKa = 4.26 PPCKK4270 pKa = 10.25 FSIQDD4275 pKa = 3.49 VKK4277 pKa = 11.06 GLKK4280 pKa = 9.3 IKK4282 pKa = 10.52 YY4283 pKa = 9.56 LYY4285 pKa = 9.85 FIKK4288 pKa = 10.74 GCNTLARR4295 pKa = 11.84 GWVVGTLSSTIRR4307 pKa = 11.84 LQAGVATEE4315 pKa = 3.99 YY4316 pKa = 10.86 AANSSILSLCAFSVDD4331 pKa = 3.62 PKK4333 pKa = 10.2 KK4334 pKa = 9.42 TYY4336 pKa = 10.72 LDD4338 pKa = 4.43 YY4339 pKa = 10.61 IQQGGVPIINCVKK4352 pKa = 9.76 MLCDD4356 pKa = 3.38 HH4357 pKa = 7.29 AGTGMAITIKK4367 pKa = 10.65 PEE4369 pKa = 3.46 ATINQDD4375 pKa = 3.01 SYY4377 pKa = 11.92 GGASVCIYY4385 pKa = 9.94 CRR4387 pKa = 11.84 ARR4389 pKa = 11.84 VEE4391 pKa = 4.36 HH4392 pKa = 7.31 PDD4394 pKa = 2.94 VDD4396 pKa = 4.97 GICKK4400 pKa = 10.12 LRR4402 pKa = 11.84 GKK4404 pKa = 9.82 FVQVPLGIKK4413 pKa = 10.42 DD4414 pKa = 3.92 PILYY4418 pKa = 10.51 VLTHH4422 pKa = 6.58 DD4423 pKa = 3.78 VCQVCGFWRR4432 pKa = 11.84 DD4433 pKa = 3.8 GSCSCVGSSVAVQSKK4448 pKa = 10.48 DD4449 pKa = 3.67 LNFLNRR4455 pKa = 11.84 VRR4457 pKa = 11.84 GTSVNARR4464 pKa = 11.84 LVPCASGLSTDD4475 pKa = 3.45 VQLRR4479 pKa = 11.84 AFDD4482 pKa = 3.31 ICNTNRR4488 pKa = 11.84 AGIGLYY4494 pKa = 10.65 YY4495 pKa = 10.48 KK4496 pKa = 10.16 VNCCRR4501 pKa = 11.84 FQRR4504 pKa = 11.84 IDD4506 pKa = 3.58 DD4507 pKa = 4.97 DD4508 pKa = 4.85 GNKK4511 pKa = 9.73 LDD4513 pKa = 3.96 KK4514 pKa = 10.94 FFVVKK4519 pKa = 9.63 RR4520 pKa = 11.84 TNLEE4524 pKa = 3.92 VYY4526 pKa = 10.1 NKK4528 pKa = 10.1 EE4529 pKa = 3.4 KK4530 pKa = 10.18 TYY4532 pKa = 11.42 YY4533 pKa = 10.11 EE4534 pKa = 4.1 LTKK4537 pKa = 10.62 SCGVVAEE4544 pKa = 4.63 HH4545 pKa = 7.61 DD4546 pKa = 4.11 FFTFDD4551 pKa = 3.13 IDD4553 pKa = 3.84 GSRR4556 pKa = 11.84 VPHH4559 pKa = 5.72 IVRR4562 pKa = 11.84 RR4563 pKa = 11.84 NLSKK4567 pKa = 10.64 YY4568 pKa = 9.05 TMLDD4572 pKa = 2.68 LCYY4575 pKa = 10.58 ALRR4578 pKa = 11.84 HH4579 pKa = 6.02 FDD4581 pKa = 5.22 RR4582 pKa = 11.84 NDD4584 pKa = 3.12 CSILCEE4590 pKa = 4.13 ILCEE4594 pKa = 3.95 YY4595 pKa = 10.81 ADD4597 pKa = 3.9 CKK4599 pKa = 10.73 EE4600 pKa = 4.6 SYY4602 pKa = 9.82 FSKK4605 pKa = 10.58 KK4606 pKa = 9.61 DD4607 pKa = 2.9 WYY4609 pKa = 10.65 DD4610 pKa = 3.36 FVEE4613 pKa = 4.76 NPDD4616 pKa = 4.02 IINIYY4621 pKa = 9.75 KK4622 pKa = 10.58 KK4623 pKa = 10.48 LGPIFNRR4630 pKa = 11.84 ALLNTVIFADD4640 pKa = 3.73 TLVEE4644 pKa = 4.13 VGLVGVLTLDD4654 pKa = 3.57 NQDD4657 pKa = 6.23 LYY4659 pKa = 10.11 GQWYY4663 pKa = 9.66 DD4664 pKa = 3.84 FGDD4667 pKa = 5.29 FIQTAPGFGVAVADD4681 pKa = 3.88 SYY4683 pKa = 11.36 YY4684 pKa = 10.86 SYY4686 pKa = 10.6 MMPMLTMCHH4695 pKa = 6.18 VLDD4698 pKa = 5.31 CEE4700 pKa = 4.71 LFVNDD4705 pKa = 5.15 SYY4707 pKa = 11.86 RR4708 pKa = 11.84 QFDD4711 pKa = 3.88 LVQYY4715 pKa = 11.04 DD4716 pKa = 3.53 FTDD4719 pKa = 3.43 YY4720 pKa = 11.3 KK4721 pKa = 11.4 LEE4723 pKa = 4.22 LFNKK4727 pKa = 8.23 YY4728 pKa = 9.44 FKK4730 pKa = 10.13 YY4731 pKa = 9.92 WGMKK4735 pKa = 7.25 YY4736 pKa = 10.16 HH4737 pKa = 7.44 PNTVDD4742 pKa = 3.78 CDD4744 pKa = 3.37 NDD4746 pKa = 3.37 RR4747 pKa = 11.84 CIIHH4751 pKa = 6.64 CANFNILFSMVLPNTCFGPLVRR4773 pKa = 11.84 QIFVDD4778 pKa = 4.47 GVPFVVSIGYY4788 pKa = 9.21 HH4789 pKa = 4.53 YY4790 pKa = 10.85 KK4791 pKa = 10.48 EE4792 pKa = 5.01 LGVVMNLDD4800 pKa = 3.63 VDD4802 pKa = 3.55 THH4804 pKa = 6.92 RR4805 pKa = 11.84 YY4806 pKa = 8.97 RR4807 pKa = 11.84 LSLKK4811 pKa = 10.71 DD4812 pKa = 3.82 LLLYY4816 pKa = 10.65 AADD4819 pKa = 3.91 PAMHH4823 pKa = 6.22 VASASALLDD4832 pKa = 3.59 LRR4834 pKa = 11.84 TCCFSVAAITSGIKK4848 pKa = 10.03 FQTVKK4853 pKa = 10.51 PGNFNQDD4860 pKa = 2.24 FYY4862 pKa = 11.74 EE4863 pKa = 4.31 FVKK4866 pKa = 10.97 SKK4868 pKa = 10.93 GLFKK4872 pKa = 10.85 EE4873 pKa = 4.85 GSTVDD4878 pKa = 3.42 LKK4880 pKa = 11.42 HH4881 pKa = 7.05 FFFTQDD4887 pKa = 2.51 GNAAITDD4894 pKa = 3.73 YY4895 pKa = 11.44 NYY4897 pKa = 11.16 YY4898 pKa = 10.53 KK4899 pKa = 11.0 YY4900 pKa = 10.66 NLPTMVDD4907 pKa = 3.11 IKK4909 pKa = 11.08 QLLFVLEE4916 pKa = 3.99 VVYY4919 pKa = 10.4 KK4920 pKa = 10.58 YY4921 pKa = 10.53 FEE4923 pKa = 4.68 IYY4925 pKa = 10.56 DD4926 pKa = 3.97 GGCIPASQVIVNNYY4940 pKa = 8.96 DD4941 pKa = 2.86 KK4942 pKa = 11.3 SAGYY4946 pKa = 9.24 PFNKK4950 pKa = 9.63 FGKK4953 pKa = 9.88 ARR4955 pKa = 11.84 LYY4957 pKa = 10.85 YY4958 pKa = 9.6 EE4959 pKa = 4.15 ALSFEE4964 pKa = 4.54 EE4965 pKa = 3.94 QNEE4968 pKa = 3.92 IYY4970 pKa = 10.17 AYY4972 pKa = 8.39 TKK4974 pKa = 10.78 RR4975 pKa = 11.84 NVLPTLTQMNLKK4987 pKa = 9.94 YY4988 pKa = 10.65 AISAKK4993 pKa = 10.06 NRR4995 pKa = 11.84 ARR4997 pKa = 11.84 TVAGVSILSTMTGRR5011 pKa = 11.84 MFHH5014 pKa = 5.5 QKK5016 pKa = 9.7 CLKK5019 pKa = 10.46 SIAATRR5025 pKa = 11.84 GVPVVIGTTKK5035 pKa = 10.61 FYY5037 pKa = 11.26 GGWDD5041 pKa = 3.25 DD5042 pKa = 4.13 MLRR5045 pKa = 11.84 HH5046 pKa = 6.73 LIKK5049 pKa = 11.03 DD5050 pKa = 3.15 VDD5052 pKa = 3.95 NPVLMGWDD5060 pKa = 3.58 YY5061 pKa = 10.84 PKK5063 pKa = 10.47 CDD5065 pKa = 2.82 RR5066 pKa = 11.84 AMPNILRR5073 pKa = 11.84 IVSSLVLARR5082 pKa = 11.84 KK5083 pKa = 9.69 HH5084 pKa = 5.82 EE5085 pKa = 4.75 FCCSHH5090 pKa = 6.64 GDD5092 pKa = 3.24 RR5093 pKa = 11.84 FYY5095 pKa = 11.61 RR5096 pKa = 11.84 LANEE5100 pKa = 4.34 CAQVLSEE5107 pKa = 4.22 IVMCGGCYY5115 pKa = 8.73 YY5116 pKa = 10.41 VKK5118 pKa = 10.58 PGGTSSGDD5126 pKa = 3.1 ATTAFANSVFNICQAVTANVCSLMACNGHH5155 pKa = 6.58 KK5156 pKa = 10.11 IEE5158 pKa = 5.25 DD5159 pKa = 3.56 LSIRR5163 pKa = 11.84 NLQKK5167 pKa = 10.38 RR5168 pKa = 11.84 LYY5170 pKa = 8.97 SNVYY5174 pKa = 7.66 RR5175 pKa = 11.84 TDD5177 pKa = 3.45 YY5178 pKa = 11.26 VDD5180 pKa = 3.23 YY5181 pKa = 10.05 TFVNEE5186 pKa = 4.27 YY5187 pKa = 11.26 YY5188 pKa = 10.66 EE5189 pKa = 4.33 FLCKK5193 pKa = 10.05 HH5194 pKa = 6.41 FSMMILSDD5202 pKa = 4.35 DD5203 pKa = 4.01 GVVCYY5208 pKa = 10.89 NSDD5211 pKa = 3.84 YY5212 pKa = 11.28 ASKK5215 pKa = 10.9 GYY5217 pKa = 9.55 IANISVFQQVLYY5229 pKa = 9.31 YY5230 pKa = 9.8 QNNVFMSEE5238 pKa = 4.15 SKK5240 pKa = 10.6 CWVEE5244 pKa = 4.2 NDD5246 pKa = 3.1 ITNGPHH5252 pKa = 6.12 EE5253 pKa = 5.06 FCSQHH5258 pKa = 4.81 TMLVKK5263 pKa = 9.79 IDD5265 pKa = 3.61 GDD5267 pKa = 4.42 YY5268 pKa = 11.41 VYY5270 pKa = 10.84 LPYY5273 pKa = 9.93 PDD5275 pKa = 4.28 PSRR5278 pKa = 11.84 ILGAGCFVDD5287 pKa = 6.23 DD5288 pKa = 4.99 LLKK5291 pKa = 10.1 TDD5293 pKa = 3.52 SVLLIEE5299 pKa = 5.05 RR5300 pKa = 11.84 FVSLAIDD5307 pKa = 4.68 AYY5309 pKa = 9.61 PLVYY5313 pKa = 10.38 HH5314 pKa = 6.54 EE5315 pKa = 4.44 NEE5317 pKa = 4.14 EE5318 pKa = 4.15 YY5319 pKa = 10.53 QKK5321 pKa = 10.86 VFRR5324 pKa = 11.84 VYY5326 pKa = 10.87 LEE5328 pKa = 4.3 YY5329 pKa = 10.29 IKK5331 pKa = 10.72 KK5332 pKa = 10.37 LYY5334 pKa = 10.23 NDD5336 pKa = 4.99 LGTQILDD5343 pKa = 3.65 SYY5345 pKa = 11.23 SVILSTCDD5353 pKa = 3.11 GLKK5356 pKa = 9.26 FTEE5359 pKa = 4.04 EE5360 pKa = 3.85 SFYY5363 pKa = 11.49 KK5364 pKa = 10.65 NMYY5367 pKa = 9.4 LKK5369 pKa = 10.37 SAVMQSVGACVVCSSQTSLRR5389 pKa = 11.84 CGSCIRR5395 pKa = 11.84 KK5396 pKa = 8.97 PLLCCKK5402 pKa = 10.05 CCYY5405 pKa = 9.61 DD5406 pKa = 4.14 HH5407 pKa = 8.7 VMATNHH5413 pKa = 6.44 KK5414 pKa = 8.58 YY5415 pKa = 9.98 VLSVSPYY5422 pKa = 8.71 VCNAPNCDD5430 pKa = 3.24 VSDD5433 pKa = 3.72 VTKK5436 pKa = 10.72 LYY5438 pKa = 10.6 LGGMSYY5444 pKa = 11.01 YY5445 pKa = 10.6 CEE5447 pKa = 3.87 NHH5449 pKa = 6.07 KK5450 pKa = 10.16 PHH5452 pKa = 6.7 YY5453 pKa = 9.94 SFKK5456 pKa = 10.88 LVMNGMVFGLYY5467 pKa = 9.61 KK5468 pKa = 10.15 QSCTGSPYY5476 pKa = 9.88 IDD5478 pKa = 4.96 DD5479 pKa = 4.02 FNKK5482 pKa = 10.11 IASCKK5487 pKa = 5.67 WTEE5490 pKa = 3.67 VDD5492 pKa = 5.8 DD5493 pKa = 4.01 YY5494 pKa = 11.96 VLANEE5499 pKa = 4.68 CIEE5502 pKa = 4.0 RR5503 pKa = 11.84 LKK5505 pKa = 11.21 LFAAEE5510 pKa = 4.12 TQKK5513 pKa = 10.22 ATEE5516 pKa = 4.04 EE5517 pKa = 4.14 AFKK5520 pKa = 10.72 QSYY5523 pKa = 10.76 ASATIQEE5530 pKa = 4.32 IVSDD5534 pKa = 4.39 RR5535 pKa = 11.84 EE5536 pKa = 4.54 VILCWEE5542 pKa = 4.26 TGKK5545 pKa = 10.68 VKK5547 pKa = 10.59 PPLNKK5552 pKa = 9.97 NYY5554 pKa = 9.97 VFTGYY5559 pKa = 10.57 HH5560 pKa = 4.95 FTSTGKK5566 pKa = 8.05 TVLGEE5571 pKa = 4.08 YY5572 pKa = 10.72 VFDD5575 pKa = 5.23 KK5576 pKa = 11.46 SEE5578 pKa = 4.07 LTNGVYY5584 pKa = 10.38 YY5585 pKa = 10.77 RR5586 pKa = 11.84 ATTTYY5591 pKa = 9.72 KK5592 pKa = 10.83 LSIGDD5597 pKa = 3.75 VFVLTSHH5604 pKa = 6.56 SVASLSAPTLVPQEE5618 pKa = 4.28 NYY5620 pKa = 10.72 ASIRR5624 pKa = 11.84 FSSVYY5629 pKa = 10.27 SVPLVFQNNVANYY5642 pKa = 7.0 QHH5644 pKa = 7.55 IGMKK5648 pKa = 9.94 RR5649 pKa = 11.84 YY5650 pKa = 8.27 CTVQGPPGTGKK5661 pKa = 9.58 SHH5663 pKa = 7.05 LAIGLAVYY5671 pKa = 10.03 YY5672 pKa = 7.56 YY5673 pKa = 7.91 TARR5676 pKa = 11.84 VVYY5679 pKa = 8.76 TAASHH5684 pKa = 6.18 AAVDD5688 pKa = 3.96 ALCEE5692 pKa = 3.83 KK5693 pKa = 10.48 AYY5695 pKa = 10.18 KK5696 pKa = 9.91 FLNINDD5702 pKa = 3.93 CTRR5705 pKa = 11.84 IIPAKK5710 pKa = 10.55 VRR5712 pKa = 11.84 VDD5714 pKa = 3.77 CYY5716 pKa = 11.73 DD5717 pKa = 3.07 KK5718 pKa = 11.32 FKK5720 pKa = 11.24 INDD5723 pKa = 3.82 TTCKK5727 pKa = 10.59 YY5728 pKa = 11.18 VFTTINALPEE5738 pKa = 4.37 LVTDD5742 pKa = 3.76 IVVVDD5747 pKa = 4.45 EE5748 pKa = 4.96 VSMLTNYY5755 pKa = 9.19 EE5756 pKa = 3.86 LSVINARR5763 pKa = 11.84 IKK5765 pKa = 10.26 AKK5767 pKa = 9.83 HH5768 pKa = 5.01 YY5769 pKa = 11.02 VYY5771 pKa = 10.45 IGDD5774 pKa = 4.21 PAQLPAPRR5782 pKa = 11.84 VLLSKK5787 pKa = 10.99 GSLEE5791 pKa = 3.76 PRR5793 pKa = 11.84 HH5794 pKa = 6.08 FNSITKK5800 pKa = 9.91 IMCCLGPDD5808 pKa = 3.12 IFLGNCYY5815 pKa = 9.84 RR5816 pKa = 11.84 CPKK5819 pKa = 9.94 EE5820 pKa = 3.64 IVEE5823 pKa = 4.51 TVSALVYY5830 pKa = 10.55 DD5831 pKa = 4.51 NKK5833 pKa = 10.94 LKK5835 pKa = 10.99 AKK5837 pKa = 9.96 NDD5839 pKa = 3.39 NSSLCFKK5846 pKa = 10.87 VYY5848 pKa = 10.27 FKK5850 pKa = 11.3 GQTTHH5855 pKa = 6.55 EE5856 pKa = 4.38 SSSAVNIQQIYY5867 pKa = 10.26 LISKK5871 pKa = 7.97 FLKK5874 pKa = 10.59 ANPVWNSAVFISPYY5888 pKa = 10.25 NSQNYY5893 pKa = 5.8 VAKK5896 pKa = 10.23 RR5897 pKa = 11.84 VLGVQTQTVDD5907 pKa = 2.99 SAQGSEE5913 pKa = 4.16 YY5914 pKa = 10.76 DD5915 pKa = 3.68 YY5916 pKa = 11.36 VIYY5919 pKa = 10.69 SQTAEE5924 pKa = 4.11 TAHH5927 pKa = 5.88 SVNVNRR5933 pKa = 11.84 FNVAITRR5940 pKa = 11.84 AKK5942 pKa = 10.42 KK5943 pKa = 10.64 GIFCVMSNMQLFEE5956 pKa = 4.27 SLNFITLPLDD5966 pKa = 4.3 KK5967 pKa = 10.34 IQNQTLPRR5975 pKa = 11.84 LHH5977 pKa = 6.58 CTTNLFKK5984 pKa = 10.89 DD5985 pKa = 3.99 CSKK5988 pKa = 11.16 SCLGYY5993 pKa = 10.61 HH5994 pKa = 7.0 PAHH5997 pKa = 6.67 APSFLAVDD6005 pKa = 4.16 DD6006 pKa = 4.45 KK6007 pKa = 12.01 YY6008 pKa = 11.53 KK6009 pKa = 10.88 VNEE6012 pKa = 3.96 NLAVNLNICEE6022 pKa = 4.07 PVLTYY6027 pKa = 10.97 SRR6029 pKa = 11.84 LISLMGFKK6037 pKa = 10.59 LDD6039 pKa = 4.02 LTLDD6043 pKa = 4.35 GYY6045 pKa = 11.76 SKK6047 pKa = 11.32 LFITKK6052 pKa = 10.02 DD6053 pKa = 3.33 EE6054 pKa = 4.71 AIKK6057 pKa = 10.35 RR6058 pKa = 11.84 VRR6060 pKa = 11.84 GWVGFDD6066 pKa = 3.15 VEE6068 pKa = 4.67 GAHH6071 pKa = 6.31 ATRR6074 pKa = 11.84 EE6075 pKa = 4.21 NIGTNFPLQIGFSTGVDD6092 pKa = 3.64 FVVEE6096 pKa = 4.11 ATGLFAEE6103 pKa = 4.71 RR6104 pKa = 11.84 DD6105 pKa = 3.74 CYY6107 pKa = 9.96 TFKK6110 pKa = 10.43 KK6111 pKa = 8.62 TVAKK6115 pKa = 10.32 APPGEE6120 pKa = 4.29 KK6121 pKa = 9.48 FKK6123 pKa = 11.24 HH6124 pKa = 6.36 LIPLMSKK6131 pKa = 7.98 GQKK6134 pKa = 8.56 WDD6136 pKa = 2.93 IVRR6139 pKa = 11.84 IRR6141 pKa = 11.84 IVQMLSDD6148 pKa = 4.19 YY6149 pKa = 11.37 LLDD6152 pKa = 4.49 LSDD6155 pKa = 3.85 SVVFITWSASFEE6167 pKa = 4.42 LTCLRR6172 pKa = 11.84 YY6173 pKa = 8.6 FAKK6176 pKa = 10.52 LGRR6179 pKa = 11.84 EE6180 pKa = 4.28 LNCNVCSNRR6189 pKa = 11.84 ATCYY6193 pKa = 10.23 NSRR6196 pKa = 11.84 TGYY6199 pKa = 8.44 YY6200 pKa = 9.07 GCWRR6204 pKa = 11.84 HH6205 pKa = 6.72 SYY6207 pKa = 8.63 TCDD6210 pKa = 3.12 YY6211 pKa = 10.73 VYY6213 pKa = 11.28 NPLIVDD6219 pKa = 4.06 IQQWGYY6225 pKa = 9.07 TGSLTSNHH6233 pKa = 7.15 DD6234 pKa = 3.78 IICNVHH6240 pKa = 6.26 KK6241 pKa = 10.21 GAHH6244 pKa = 5.36 VASADD6249 pKa = 3.94 AIMTRR6254 pKa = 11.84 CLAIYY6259 pKa = 10.34 DD6260 pKa = 4.21 CFCKK6264 pKa = 10.35 SVNWNLEE6271 pKa = 3.63 YY6272 pKa = 10.14 PIISNEE6278 pKa = 3.63 VSINTSCRR6286 pKa = 11.84 LLQRR6290 pKa = 11.84 VMLKK6294 pKa = 10.74 AAMLCNRR6301 pKa = 11.84 YY6302 pKa = 8.9 NLCYY6306 pKa = 10.52 DD6307 pKa = 3.27 IGNPKK6312 pKa = 10.07 GLACVKK6318 pKa = 10.35 DD6319 pKa = 4.05 YY6320 pKa = 11.3 EE6321 pKa = 4.63 FKK6323 pKa = 10.7 FYY6325 pKa = 11.08 DD6326 pKa = 3.82 AFPVAKK6332 pKa = 9.9 SVKK6335 pKa = 9.21 QLFYY6339 pKa = 11.11 VYY6341 pKa = 10.24 DD6342 pKa = 3.48 VHH6344 pKa = 8.45 KK6345 pKa = 11.18 DD6346 pKa = 3.28 NFKK6349 pKa = 11.23 DD6350 pKa = 3.93 GLCMFWNCNVDD6361 pKa = 3.51 KK6362 pKa = 10.88 YY6363 pKa = 10.42 PSNSIVCRR6371 pKa = 11.84 FDD6373 pKa = 3.28 TRR6375 pKa = 11.84 VLNKK6379 pKa = 10.46 LNLPGCNGGSLYY6391 pKa = 10.89 VNKK6394 pKa = 10.15 HH6395 pKa = 5.43 AFHH6398 pKa = 6.92 TNPFTRR6404 pKa = 11.84 TVFEE6408 pKa = 4.36 NLKK6411 pKa = 10.24 PMPFFYY6417 pKa = 11.0 YY6418 pKa = 10.43 SDD6420 pKa = 3.89 TPCVYY6425 pKa = 10.83 VDD6427 pKa = 3.58 GLEE6430 pKa = 4.28 SKK6432 pKa = 10.55 QVDD6435 pKa = 4.05 YY6436 pKa = 11.62 VPLRR6440 pKa = 11.84 SATCITRR6447 pKa = 11.84 CNLGGAVCSKK6457 pKa = 10.5 HH6458 pKa = 7.46 AEE6460 pKa = 4.24 EE6461 pKa = 4.38 YY6462 pKa = 10.65 CNYY6465 pKa = 10.0 LEE6467 pKa = 4.92 SYY6469 pKa = 10.77 NIVTTAGFTFWVYY6482 pKa = 11.54 KK6483 pKa = 10.97 NFDD6486 pKa = 4.61 FYY6488 pKa = 11.97 NLWNTFTTLQSLEE6501 pKa = 3.94 NVIYY6505 pKa = 10.47 NLVNVGHH6512 pKa = 6.33 YY6513 pKa = 10.26 DD6514 pKa = 3.18 GRR6516 pKa = 11.84 TGEE6519 pKa = 4.25 LPCAIMNDD6527 pKa = 3.4 KK6528 pKa = 10.9 VVVKK6532 pKa = 10.11 INNVDD6537 pKa = 3.49 TVIFKK6542 pKa = 11.12 NNTSFPTNIAVEE6554 pKa = 4.53 LFTKK6558 pKa = 10.41 RR6559 pKa = 11.84 SIRR6562 pKa = 11.84 HH6563 pKa = 5.25 HH6564 pKa = 7.15 PEE6566 pKa = 3.41 LKK6568 pKa = 10.03 ILRR6571 pKa = 11.84 NLNIDD6576 pKa = 3.44 ICWKK6580 pKa = 10.17 HH6581 pKa = 5.67 VLWDD6585 pKa = 3.78 YY6586 pKa = 11.82 VKK6588 pKa = 11.0 DD6589 pKa = 3.81 SLFCSSTYY6597 pKa = 10.51 GVCKK6601 pKa = 9.98 YY6602 pKa = 9.32 TDD6604 pKa = 3.18 LKK6606 pKa = 11.08 FIEE6609 pKa = 4.42 NLNILFDD6616 pKa = 4.05 GRR6618 pKa = 11.84 DD6619 pKa = 3.4 TGALEE6624 pKa = 4.34 AFRR6627 pKa = 11.84 KK6628 pKa = 9.3 ARR6630 pKa = 11.84 NGVFISTEE6638 pKa = 3.81 KK6639 pKa = 10.69 LSRR6642 pKa = 11.84 LSMIKK6647 pKa = 10.29 GPQRR6651 pKa = 11.84 ADD6653 pKa = 3.38 LNGVIVDD6660 pKa = 3.9 KK6661 pKa = 11.43 VGEE6664 pKa = 4.18 LKK6666 pKa = 10.92 VEE6668 pKa = 4.65 FWFAMRR6674 pKa = 11.84 KK6675 pKa = 10.4 DD6676 pKa = 3.49 GDD6678 pKa = 3.84 DD6679 pKa = 3.89 VIFSRR6684 pKa = 11.84 TDD6686 pKa = 3.27 SLCSSHH6692 pKa = 6.26 YY6693 pKa = 9.66 WSPQGNLGGNCAGNVIGNDD6712 pKa = 2.85 ALTRR6716 pKa = 11.84 FTIFTQSRR6724 pKa = 11.84 VLSSFEE6730 pKa = 3.81 PRR6732 pKa = 11.84 SDD6734 pKa = 3.92 LEE6736 pKa = 4.06 RR6737 pKa = 11.84 DD6738 pKa = 4.17 FIDD6741 pKa = 3.46 MDD6743 pKa = 4.74 DD6744 pKa = 3.87 NLFIAKK6750 pKa = 10.16 YY6751 pKa = 10.05 GLEE6754 pKa = 4.82 DD6755 pKa = 3.43 YY6756 pKa = 11.33 AFDD6759 pKa = 4.83 HH6760 pKa = 6.38 IVYY6763 pKa = 10.37 GSFNHH6768 pKa = 6.26 KK6769 pKa = 10.52 VIGGLHH6775 pKa = 6.11 LLIGLFRR6782 pKa = 11.84 RR6783 pKa = 11.84 LKK6785 pKa = 10.48 KK6786 pKa = 10.77 SNLLIQEE6793 pKa = 4.46 FLQYY6797 pKa = 10.84 DD6798 pKa = 4.0 SSIHH6802 pKa = 6.59 SYY6804 pKa = 10.79 FITDD6808 pKa = 3.57 QEE6810 pKa = 4.62 CGSSKK6815 pKa = 10.48 SVCTVIDD6822 pKa = 4.05 LLLDD6826 pKa = 3.91 DD6827 pKa = 5.23 FVSIVKK6833 pKa = 10.05 SLNLSCVSKK6842 pKa = 10.83 VVNINVDD6849 pKa = 3.87 FKK6851 pKa = 11.52 DD6852 pKa = 3.83 FQFMLWCNDD6861 pKa = 3.03 NKK6863 pKa = 10.63 IMTFYY6868 pKa = 10.92 PKK6870 pKa = 9.5 MQATNDD6876 pKa = 3.54 WKK6878 pKa = 10.13 PGYY6881 pKa = 10.38 SMPVLYY6887 pKa = 10.26 KK6888 pKa = 10.21 YY6889 pKa = 11.07 LNVPLEE6895 pKa = 4.74 RR6896 pKa = 11.84 VSLWNYY6902 pKa = 7.73 GKK6904 pKa = 9.81 PINLPTGCMMNVAKK6918 pKa = 9.22 YY6919 pKa = 7.58 TQLCQYY6925 pKa = 11.27 LNTTTLAVPVNMRR6938 pKa = 11.84 VLHH6941 pKa = 6.53 LGAGSDD6947 pKa = 3.76 KK6948 pKa = 10.63 EE6949 pKa = 4.36 VAPGSAVLRR6958 pKa = 11.84 QWLPSGSILVDD6969 pKa = 2.96 NDD6971 pKa = 3.68 LNPFVSDD6978 pKa = 3.55 SLVTYY6983 pKa = 10.62 FGDD6986 pKa = 4.73 CMTLPFDD6993 pKa = 4.28 CHH6995 pKa = 6.46 WDD6997 pKa = 4.22 LIISDD7002 pKa = 4.47 MYY7004 pKa = 11.66 DD7005 pKa = 3.51 PLTKK7009 pKa = 10.68 NIGDD7013 pKa = 3.92 YY7014 pKa = 10.75 NVSKK7018 pKa = 11.0 DD7019 pKa = 3.33 GFFTYY7024 pKa = 9.68 ICHH7027 pKa = 8.15 LIRR7030 pKa = 11.84 DD7031 pKa = 4.16 KK7032 pKa = 11.43 LSLGGSVAIKK7042 pKa = 8.94 ITEE7045 pKa = 4.24 FSWNADD7051 pKa = 3.3 LYY7053 pKa = 11.75 KK7054 pKa = 10.94 LMSCFAFWTVFCTNVNASSSEE7075 pKa = 3.72 GFLIGINYY7083 pKa = 9.48 LGKK7086 pKa = 10.46 SSFEE7090 pKa = 3.52 IDD7092 pKa = 3.62 GNVMHH7097 pKa = 7.35 ANYY7100 pKa = 10.3 LFWRR7104 pKa = 11.84 NSTTWNGGAYY7114 pKa = 10.45 SLFDD7118 pKa = 3.27 MTKK7121 pKa = 10.46 FSLKK7125 pKa = 10.37 LAGTAVVNLRR7135 pKa = 11.84 PDD7137 pKa = 3.34 QLNDD7141 pKa = 3.39 LVYY7144 pKa = 11.17 SLIEE7148 pKa = 4.04 RR7149 pKa = 11.84 GKK7151 pKa = 10.85 LLVRR7155 pKa = 11.84 DD7156 pKa = 3.69 TRR7158 pKa = 11.84 KK7159 pKa = 10.35 EE7160 pKa = 3.83 IFVGDD7165 pKa = 4.16 SLVNTCC7171 pKa = 5.52
Molecular weight: 810.04 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.268
IPC2_protein 5.474
IPC_protein 5.525
Toseland 5.728
ProMoST 5.842
Dawson 5.741
Bjellqvist 5.792
Wikipedia 5.728
Rodwell 5.703
Grimsley 5.792
Solomon 5.741
Lehninger 5.728
Nozaki 5.982
DTASelect 6.186
Thurlkill 6.122
EMBOSS 6.084
Sillero 6.071
Patrickios 1.494
IPC_peptide 5.753
IPC2_peptide 6.059
IPC2.peptide.svr19 5.985
Protein with the highest isoelectric point:
>tr|Q0ZJ83|Q0ZJ83_CVHK1 Envelope small membrane protein OS=Human coronavirus HKU1 OX=290028 GN=E PE=3 SV=1
MM1 pKa = 7.39 NKK3 pKa = 9.94 SFFPQFTSDD12 pKa = 3.34 QAVTFLKK19 pKa = 10.18 EE20 pKa = 3.9 WNFSLGVILLFITIILQFGYY40 pKa = 8.53 TSRR43 pKa = 11.84 SMFVYY48 pKa = 9.42 FIKK51 pKa = 10.33 MIILWLMWPLTITLTIFNCFYY72 pKa = 11.24 ALNNAFLAFSIVFTIISIVIWILYY96 pKa = 7.02 FVNSIRR102 pKa = 11.84 LFIRR106 pKa = 11.84 TGSWWSFNPEE116 pKa = 4.27 TNNLMCIDD124 pKa = 4.15 MKK126 pKa = 11.13 GKK128 pKa = 8.92 MFVRR132 pKa = 11.84 PVIEE136 pKa = 5.25 DD137 pKa = 3.63 YY138 pKa = 8.98 HH139 pKa = 6.08 TLTATVIRR147 pKa = 11.84 GHH149 pKa = 7.22 LYY151 pKa = 9.12 IQGVKK156 pKa = 10.4 LGTGYY161 pKa = 8.52 TLSDD165 pKa = 3.64 LPVYY169 pKa = 9.15 VTVAKK174 pKa = 10.7 VQVLCTYY181 pKa = 10.41 KK182 pKa = 10.58 RR183 pKa = 11.84 AFLDD187 pKa = 3.59 KK188 pKa = 11.03 LDD190 pKa = 4.07 VNSGFAVFVKK200 pKa = 10.54 SKK202 pKa = 9.76 VGNYY206 pKa = 9.12 RR207 pKa = 11.84 LPSSKK212 pKa = 10.18 PSGMDD217 pKa = 3.09 TALLRR222 pKa = 11.84 AA223 pKa = 4.27
Molecular weight: 25.69 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 8.843
IPC2_protein 9.165
IPC_protein 9.107
Toseland 9.56
ProMoST 9.414
Dawson 9.882
Bjellqvist 9.633
Wikipedia 10.072
Rodwell 10.116
Grimsley 9.97
Solomon 9.911
Lehninger 9.867
Nozaki 9.663
DTASelect 9.589
Thurlkill 9.692
EMBOSS 9.999
Sillero 9.809
Patrickios 4.622
IPC_peptide 9.897
IPC2_peptide 8.39
IPC2.peptide.svr19 8.018
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
8
0
8
9973
82
7171
1246.6
140.77
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
5.144 ± 0.605
3.58 ± 0.437
6.247 ± 0.958
3.349 ± 0.311
6.317 ± 0.555
5.605 ± 0.206
1.945 ± 0.139
5.956 ± 0.467
5.645 ± 0.385
9.476 ± 0.928
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.015 ± 0.423
6.177 ± 0.706
3.409 ± 0.661
2.948 ± 0.305
3.128 ± 0.299
7.941 ± 1.447
5.445 ± 0.414
9.004 ± 1.309
1.263 ± 0.105
5.405 ± 0.459
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here