Amino acid dipepetide frequency for Shuangao sobemo-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.754AlaAla: 5.754 ± 3.45
2.301AlaCys: 2.301 ± 0.225
1.151AlaAsp: 1.151 ± 0.69
1.151AlaGlu: 1.151 ± 0.915
3.452AlaPhe: 3.452 ± 0.465
8.055AlaGly: 8.055 ± 1.619
0.0AlaHis: 0.0 ± 0.0
6.904AlaIle: 6.904 ± 4.14
0.0AlaLys: 0.0 ± 0.0
4.603AlaLeu: 4.603 ± 2.056
1.151AlaMet: 1.151 ± 0.477
2.301AlaAsn: 2.301 ± 1.38
1.151AlaPro: 1.151 ± 0.69
2.301AlaGln: 2.301 ± 0.225
1.151AlaArg: 1.151 ± 0.69
3.452AlaSer: 3.452 ± 0.465
1.151AlaThr: 1.151 ± 0.69
2.301AlaVal: 2.301 ± 1.38
1.151AlaTrp: 1.151 ± 0.915
4.603AlaTyr: 4.603 ± 2.76
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.151CysCys: 1.151 ± 0.69
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.151CysPhe: 1.151 ± 0.915
2.301CysGly: 2.301 ± 0.225
0.0CysHis: 0.0 ± 0.0
3.452CysIle: 3.452 ± 0.465
0.0CysLys: 0.0 ± 0.0
1.151CysLeu: 1.151 ± 0.915
2.301CysMet: 2.301 ± 1.38
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.151CysGln: 1.151 ± 0.69
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.151CysThr: 1.151 ± 0.69
4.603CysVal: 4.603 ± 2.056
0.0CysTrp: 0.0 ± 0.0
3.452CysTyr: 3.452 ± 1.141
0.0CysXaa: 0.0 ± 0.0
Asp
3.452AspAla: 3.452 ± 1.141
0.0AspCys: 0.0 ± 0.0
2.301AspAsp: 2.301 ± 0.225
2.301AspGlu: 2.301 ± 0.225
4.603AspPhe: 4.603 ± 3.661
3.452AspGly: 3.452 ± 0.465
2.301AspHis: 2.301 ± 1.831
1.151AspIle: 1.151 ± 0.915
4.603AspLys: 4.603 ± 2.056
6.904AspLeu: 6.904 ± 2.281
1.151AspMet: 1.151 ± 0.69
1.151AspAsn: 1.151 ± 0.915
2.301AspPro: 2.301 ± 0.225
2.301AspGln: 2.301 ± 1.38
0.0AspArg: 0.0 ± 0.0
4.603AspSer: 4.603 ± 1.155
2.301AspThr: 2.301 ± 1.38
2.301AspVal: 2.301 ± 0.225
2.301AspTrp: 2.301 ± 1.831
3.452AspTyr: 3.452 ± 0.465
0.0AspXaa: 0.0 ± 0.0
Glu
3.452GluAla: 3.452 ± 1.141
1.151GluCys: 1.151 ± 0.69
2.301GluAsp: 2.301 ± 1.38
2.301GluGlu: 2.301 ± 0.225
3.452GluPhe: 3.452 ± 1.141
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
6.904GluIle: 6.904 ± 0.676
6.904GluLys: 6.904 ± 2.281
1.151GluLeu: 1.151 ± 0.69
0.0GluMet: 0.0 ± 0.0
2.301GluAsn: 2.301 ± 0.225
1.151GluPro: 1.151 ± 0.915
2.301GluGln: 2.301 ± 1.831
2.301GluArg: 2.301 ± 1.38
8.055GluSer: 8.055 ± 1.619
1.151GluThr: 1.151 ± 0.69
2.301GluVal: 2.301 ± 1.38
1.151GluTrp: 1.151 ± 0.915
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.301PheAla: 2.301 ± 1.38
2.301PheCys: 2.301 ± 0.225
4.603PheAsp: 4.603 ± 0.451
3.452PheGlu: 3.452 ± 0.465
1.151PhePhe: 1.151 ± 0.69
1.151PheGly: 1.151 ± 0.69
2.301PheHis: 2.301 ± 0.225
3.452PheIle: 3.452 ± 1.141
2.301PheLys: 2.301 ± 1.38
6.904PheLeu: 6.904 ± 0.676
0.0PheMet: 0.0 ± 0.0
2.301PheAsn: 2.301 ± 0.225
0.0PhePro: 0.0 ± 0.0
2.301PheGln: 2.301 ± 0.225
4.603PheArg: 4.603 ± 0.451
8.055PheSer: 8.055 ± 0.014
1.151PheThr: 1.151 ± 0.69
1.151PheVal: 1.151 ± 0.915
2.301PheTrp: 2.301 ± 0.225
2.301PheTyr: 2.301 ± 1.831
0.0PheXaa: 0.0 ± 0.0
Gly
2.301GlyAla: 2.301 ± 1.38
2.301GlyCys: 2.301 ± 0.225
2.301GlyAsp: 2.301 ± 1.831
1.151GlyGlu: 1.151 ± 0.69
2.301GlyPhe: 2.301 ± 0.225
3.452GlyGly: 3.452 ± 2.07
3.452GlyHis: 3.452 ± 1.141
2.301GlyIle: 2.301 ± 0.225
4.603GlyLys: 4.603 ± 1.155
2.301GlyLeu: 2.301 ± 0.225
3.452GlyMet: 3.452 ± 0.465
3.452GlyAsn: 3.452 ± 2.07
3.452GlyPro: 3.452 ± 0.465
3.452GlyGln: 3.452 ± 1.141
4.603GlyArg: 4.603 ± 0.451
5.754GlySer: 5.754 ± 0.239
4.603GlyThr: 4.603 ± 2.76
4.603GlyVal: 4.603 ± 0.451
1.151GlyTrp: 1.151 ± 0.69
4.603GlyTyr: 4.603 ± 2.76
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
3.452HisAsp: 3.452 ± 1.141
0.0HisGlu: 0.0 ± 0.0
2.301HisPhe: 2.301 ± 1.38
4.603HisGly: 4.603 ± 0.451
0.0HisHis: 0.0 ± 0.0
2.301HisIle: 2.301 ± 0.225
1.151HisLys: 1.151 ± 0.915
1.151HisLeu: 1.151 ± 0.915
1.151HisMet: 1.151 ± 0.915
1.151HisAsn: 1.151 ± 0.915
1.151HisPro: 1.151 ± 0.69
0.0HisGln: 0.0 ± 0.0
1.151HisArg: 1.151 ± 0.915
3.452HisSer: 3.452 ± 1.141
0.0HisThr: 0.0 ± 0.0
2.301HisVal: 2.301 ± 1.38
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.603IleAla: 4.603 ± 0.451
0.0IleCys: 0.0 ± 0.0
2.301IleAsp: 2.301 ± 1.38
4.603IleGlu: 4.603 ± 0.451
0.0IlePhe: 0.0 ± 0.0
6.904IleGly: 6.904 ± 0.929
1.151IleHis: 1.151 ± 0.69
3.452IleIle: 3.452 ± 0.465
5.754IleLys: 5.754 ± 0.239
4.603IleLeu: 4.603 ± 2.056
3.452IleMet: 3.452 ± 1.141
5.754IleAsn: 5.754 ± 0.239
9.206IlePro: 9.206 ± 2.309
4.603IleGln: 4.603 ± 1.155
5.754IleArg: 5.754 ± 3.45
2.301IleSer: 2.301 ± 0.225
1.151IleThr: 1.151 ± 0.69
4.603IleVal: 4.603 ± 1.155
0.0IleTrp: 0.0 ± 0.0
2.301IleTyr: 2.301 ± 1.831
0.0IleXaa: 0.0 ± 0.0
Lys
1.151LysAla: 1.151 ± 0.915
0.0LysCys: 0.0 ± 0.0
2.301LysAsp: 2.301 ± 1.38
2.301LysGlu: 2.301 ± 0.225
8.055LysPhe: 8.055 ± 1.619
2.301LysGly: 2.301 ± 1.831
2.301LysHis: 2.301 ± 1.831
6.904LysIle: 6.904 ± 0.676
3.452LysLys: 3.452 ± 2.746
3.452LysLeu: 3.452 ± 1.141
1.151LysMet: 1.151 ± 0.915
3.452LysAsn: 3.452 ± 2.07
3.452LysPro: 3.452 ± 1.141
2.301LysGln: 2.301 ± 0.225
6.904LysArg: 6.904 ± 0.676
6.904LysSer: 6.904 ± 0.676
1.151LysThr: 1.151 ± 0.69
1.151LysVal: 1.151 ± 0.915
1.151LysTrp: 1.151 ± 0.69
2.301LysTyr: 2.301 ± 1.831
0.0LysXaa: 0.0 ± 0.0
Leu
6.904LeuAla: 6.904 ± 0.676
0.0LeuCys: 0.0 ± 0.0
6.904LeuAsp: 6.904 ± 3.887
2.301LeuGlu: 2.301 ± 1.831
3.452LeuPhe: 3.452 ± 1.141
1.151LeuGly: 1.151 ± 0.69
0.0LeuHis: 0.0 ± 0.0
8.055LeuIle: 8.055 ± 1.591
2.301LeuLys: 2.301 ± 0.225
2.301LeuLeu: 2.301 ± 1.831
2.301LeuMet: 2.301 ± 0.225
3.452LeuAsn: 3.452 ± 1.141
3.452LeuPro: 3.452 ± 2.746
2.301LeuGln: 2.301 ± 0.225
3.452LeuArg: 3.452 ± 0.465
10.357LeuSer: 10.357 ± 0.212
1.151LeuThr: 1.151 ± 0.69
5.754LeuVal: 5.754 ± 0.239
3.452LeuTrp: 3.452 ± 2.746
3.452LeuTyr: 3.452 ± 2.746
0.0LeuXaa: 0.0 ± 0.0
Met
3.452MetAla: 3.452 ± 2.07
1.151MetCys: 1.151 ± 0.915
3.452MetAsp: 3.452 ± 1.141
3.452MetGlu: 3.452 ± 1.141
1.151MetPhe: 1.151 ± 0.915
1.151MetGly: 1.151 ± 0.915
1.151MetHis: 1.151 ± 0.69
1.151MetIle: 1.151 ± 0.69
2.301MetLys: 2.301 ± 0.225
1.151MetLeu: 1.151 ± 0.915
0.0MetMet: 0.0 ± 0.0
1.151MetAsn: 1.151 ± 0.69
2.301MetPro: 2.301 ± 0.225
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.151MetSer: 1.151 ± 0.915
0.0MetThr: 0.0 ± 0.0
2.301MetVal: 2.301 ± 1.38
0.0MetTrp: 0.0 ± 0.0
1.151MetTyr: 1.151 ± 0.915
0.0MetXaa: 0.0 ± 0.0
Asn
2.301AsnAla: 2.301 ± 0.225
1.151AsnCys: 1.151 ± 0.69
2.301AsnAsp: 2.301 ± 0.225
4.603AsnGlu: 4.603 ± 1.155
3.452AsnPhe: 3.452 ± 0.465
2.301AsnGly: 2.301 ± 0.225
2.301AsnHis: 2.301 ± 1.38
2.301AsnIle: 2.301 ± 1.38
0.0AsnLys: 0.0 ± 0.0
6.904AsnLeu: 6.904 ± 0.676
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.301AsnPro: 2.301 ± 1.38
0.0AsnGln: 0.0 ± 0.0
3.452AsnArg: 3.452 ± 2.07
3.452AsnSer: 3.452 ± 1.141
5.754AsnThr: 5.754 ± 1.845
2.301AsnVal: 2.301 ± 0.225
1.151AsnTrp: 1.151 ± 0.69
2.301AsnTyr: 2.301 ± 0.225
0.0AsnXaa: 0.0 ± 0.0
Pro
1.151ProAla: 1.151 ± 0.69
0.0ProCys: 0.0 ± 0.0
2.301ProAsp: 2.301 ± 1.831
4.603ProGlu: 4.603 ± 1.155
0.0ProPhe: 0.0 ± 0.0
3.452ProGly: 3.452 ± 0.465
2.301ProHis: 2.301 ± 0.225
5.754ProIle: 5.754 ± 0.239
1.151ProLys: 1.151 ± 0.69
5.754ProLeu: 5.754 ± 2.971
0.0ProMet: 0.0 ± 0.0
2.301ProAsn: 2.301 ± 1.38
2.301ProPro: 2.301 ± 1.38
0.0ProGln: 0.0 ± 0.0
2.301ProArg: 2.301 ± 1.38
4.603ProSer: 4.603 ± 1.155
3.452ProThr: 3.452 ± 0.465
4.603ProVal: 4.603 ± 2.056
0.0ProTrp: 0.0 ± 0.0
3.452ProTyr: 3.452 ± 1.141
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
2.301GlnCys: 2.301 ± 1.38
2.301GlnAsp: 2.301 ± 0.225
1.151GlnGlu: 1.151 ± 0.69
1.151GlnPhe: 1.151 ± 0.69
2.301GlnGly: 2.301 ± 0.225
0.0GlnHis: 0.0 ± 0.0
3.452GlnIle: 3.452 ± 1.141
2.301GlnLys: 2.301 ± 0.225
3.452GlnLeu: 3.452 ± 0.465
0.0GlnMet: 0.0 ± 0.0
3.452GlnAsn: 3.452 ± 1.141
0.0GlnPro: 0.0 ± 0.0
1.151GlnGln: 1.151 ± 0.69
1.151GlnArg: 1.151 ± 0.915
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
3.452GlnVal: 3.452 ± 1.141
2.301GlnTrp: 2.301 ± 1.831
2.301GlnTyr: 2.301 ± 0.225
0.0GlnXaa: 0.0 ± 0.0
Arg
3.452ArgAla: 3.452 ± 2.07
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
2.301ArgGlu: 2.301 ± 1.831
3.452ArgPhe: 3.452 ± 0.465
4.603ArgGly: 4.603 ± 1.155
1.151ArgHis: 1.151 ± 0.69
4.603ArgIle: 4.603 ± 2.76
4.603ArgLys: 4.603 ± 0.451
4.603ArgLeu: 4.603 ± 2.056
1.151ArgMet: 1.151 ± 0.915
1.151ArgAsn: 1.151 ± 0.69
1.151ArgPro: 1.151 ± 0.69
2.301ArgGln: 2.301 ± 1.831
2.301ArgArg: 2.301 ± 1.38
5.754ArgSer: 5.754 ± 1.845
3.452ArgThr: 3.452 ± 2.07
3.452ArgVal: 3.452 ± 0.465
1.151ArgTrp: 1.151 ± 0.915
3.452ArgTyr: 3.452 ± 1.141
0.0ArgXaa: 0.0 ± 0.0
Ser
6.904SerAla: 6.904 ± 4.14
1.151SerCys: 1.151 ± 0.69
3.452SerAsp: 3.452 ± 0.465
6.904SerGlu: 6.904 ± 0.676
4.603SerPhe: 4.603 ± 0.451
5.754SerGly: 5.754 ± 0.239
2.301SerHis: 2.301 ± 0.225
5.754SerIle: 5.754 ± 1.845
6.904SerLys: 6.904 ± 0.676
6.904SerLeu: 6.904 ± 0.676
3.452SerMet: 3.452 ± 0.439
2.301SerAsn: 2.301 ± 1.38
4.603SerPro: 4.603 ± 0.451
0.0SerGln: 0.0 ± 0.0
5.754SerArg: 5.754 ± 0.239
6.904SerSer: 6.904 ± 2.535
6.904SerThr: 6.904 ± 0.929
3.452SerVal: 3.452 ± 0.465
1.151SerTrp: 1.151 ± 0.69
2.301SerTyr: 2.301 ± 1.831
0.0SerXaa: 0.0 ± 0.0
Thr
3.452ThrAla: 3.452 ± 2.07
1.151ThrCys: 1.151 ± 0.69
1.151ThrAsp: 1.151 ± 0.69
3.452ThrGlu: 3.452 ± 2.07
0.0ThrPhe: 0.0 ± 0.0
3.452ThrGly: 3.452 ± 2.07
1.151ThrHis: 1.151 ± 0.915
2.301ThrIle: 2.301 ± 0.225
3.452ThrLys: 3.452 ± 2.07
0.0ThrLeu: 0.0 ± 0.0
1.151ThrMet: 1.151 ± 0.915
3.452ThrAsn: 3.452 ± 0.465
3.452ThrPro: 3.452 ± 0.465
0.0ThrGln: 0.0 ± 0.0
1.151ThrArg: 1.151 ± 0.69
4.603ThrSer: 4.603 ± 2.76
4.603ThrThr: 4.603 ± 2.76
3.452ThrVal: 3.452 ± 0.465
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.603ValAla: 4.603 ± 1.155
3.452ValCys: 3.452 ± 2.746
2.301ValAsp: 2.301 ± 0.225
2.301ValGlu: 2.301 ± 0.225
2.301ValPhe: 2.301 ± 1.38
4.603ValGly: 4.603 ± 1.155
1.151ValHis: 1.151 ± 0.915
1.151ValIle: 1.151 ± 0.69
4.603ValLys: 4.603 ± 2.056
3.452ValLeu: 3.452 ± 0.465
1.151ValMet: 1.151 ± 0.69
8.055ValAsn: 8.055 ± 3.224
5.754ValPro: 5.754 ± 0.239
3.452ValGln: 3.452 ± 1.141
1.151ValArg: 1.151 ± 0.915
1.151ValSer: 1.151 ± 0.69
0.0ValThr: 0.0 ± 0.0
4.603ValVal: 4.603 ± 1.155
1.151ValTrp: 1.151 ± 0.915
4.603ValTyr: 4.603 ± 1.155
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.301TrpAsp: 2.301 ± 1.831
0.0TrpGlu: 0.0 ± 0.0
2.301TrpPhe: 2.301 ± 0.225
1.151TrpGly: 1.151 ± 0.69
1.151TrpHis: 1.151 ± 0.915
0.0TrpIle: 0.0 ± 0.0
3.452TrpLys: 3.452 ± 1.141
3.452TrpLeu: 3.452 ± 1.141
0.0TrpMet: 0.0 ± 0.0
1.151TrpAsn: 1.151 ± 0.915
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.301TrpArg: 2.301 ± 1.831
1.151TrpSer: 1.151 ± 0.69
1.151TrpThr: 1.151 ± 0.915
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.151TrpTyr: 1.151 ± 0.915
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
2.301TyrCys: 2.301 ± 1.831
5.754TyrAsp: 5.754 ± 2.971
0.0TyrGlu: 0.0 ± 0.0
5.754TyrPhe: 5.754 ± 0.239
3.452TyrGly: 3.452 ± 0.465
1.151TyrHis: 1.151 ± 0.69
1.151TyrIle: 1.151 ± 0.69
2.301TyrLys: 2.301 ± 1.831
2.301TyrLeu: 2.301 ± 0.225
3.452TyrMet: 3.452 ± 1.141
0.0TyrAsn: 0.0 ± 0.0
2.301TyrPro: 2.301 ± 1.831
2.301TyrGln: 2.301 ± 0.225
4.603TyrArg: 4.603 ± 0.451
5.754TyrSer: 5.754 ± 0.239
1.151TyrThr: 1.151 ± 0.915
2.301TyrVal: 2.301 ± 1.38
1.151TyrTrp: 1.151 ± 0.915
1.151TyrTyr: 1.151 ± 0.915
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (870 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski