Amino acid dipepetide frequency for Hubei picorna-like virus 27

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.28AlaAla: 3.28 ± 0.0
0.328AlaCys: 0.328 ± 0.0
2.952AlaAsp: 2.952 ± 0.0
2.952AlaGlu: 2.952 ± 0.0
2.952AlaPhe: 2.952 ± 0.0
2.296AlaGly: 2.296 ± 0.0
1.312AlaHis: 1.312 ± 0.0
3.28AlaIle: 3.28 ± 0.0
2.624AlaLys: 2.624 ± 0.0
4.92AlaLeu: 4.92 ± 0.0
0.984AlaMet: 0.984 ± 0.0
2.952AlaAsn: 2.952 ± 0.0
2.296AlaPro: 2.296 ± 0.0
0.656AlaGln: 0.656 ± 0.0
2.296AlaArg: 2.296 ± 0.0
4.92AlaSer: 4.92 ± 0.0
1.64AlaThr: 1.64 ± 0.0
3.28AlaVal: 3.28 ± 0.0
0.656AlaTrp: 0.656 ± 0.0
2.624AlaTyr: 2.624 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.312CysAla: 1.312 ± 0.0
0.328CysCys: 0.328 ± 0.0
1.64CysAsp: 1.64 ± 0.0
1.64CysGlu: 1.64 ± 0.0
0.328CysPhe: 0.328 ± 0.0
1.64CysGly: 1.64 ± 0.0
0.328CysHis: 0.328 ± 0.0
1.968CysIle: 1.968 ± 0.0
0.656CysLys: 0.656 ± 0.0
1.968CysLeu: 1.968 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.328CysAsn: 0.328 ± 0.0
0.656CysPro: 0.656 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.984CysArg: 0.984 ± 0.0
0.656CysSer: 0.656 ± 0.0
0.984CysThr: 0.984 ± 0.0
0.328CysVal: 0.328 ± 0.0
0.328CysTrp: 0.328 ± 0.0
0.328CysTyr: 0.328 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.608AspAla: 3.608 ± 0.0
1.312AspCys: 1.312 ± 0.0
2.296AspAsp: 2.296 ± 0.0
1.968AspGlu: 1.968 ± 0.0
3.28AspPhe: 3.28 ± 0.0
2.624AspGly: 2.624 ± 0.0
0.984AspHis: 0.984 ± 0.0
4.264AspIle: 4.264 ± 0.0
3.936AspLys: 3.936 ± 0.0
5.904AspLeu: 5.904 ± 0.0
2.296AspMet: 2.296 ± 0.0
3.608AspAsn: 3.608 ± 0.0
2.296AspPro: 2.296 ± 0.0
0.984AspGln: 0.984 ± 0.0
3.28AspArg: 3.28 ± 0.0
4.592AspSer: 4.592 ± 0.0
1.312AspThr: 1.312 ± 0.0
3.936AspVal: 3.936 ± 0.0
1.64AspTrp: 1.64 ± 0.0
3.28AspTyr: 3.28 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.624GluAla: 2.624 ± 0.0
0.0GluCys: 0.0 ± 0.0
3.28GluAsp: 3.28 ± 0.0
3.28GluGlu: 3.28 ± 0.0
2.952GluPhe: 2.952 ± 0.0
2.952GluGly: 2.952 ± 0.0
0.328GluHis: 0.328 ± 0.0
4.264GluIle: 4.264 ± 0.0
3.936GluLys: 3.936 ± 0.0
4.92GluLeu: 4.92 ± 0.0
3.608GluMet: 3.608 ± 0.0
2.296GluAsn: 2.296 ± 0.0
4.92GluPro: 4.92 ± 0.0
1.312GluGln: 1.312 ± 0.0
1.64GluArg: 1.64 ± 0.0
3.28GluSer: 3.28 ± 0.0
3.936GluThr: 3.936 ± 0.0
4.592GluVal: 4.592 ± 0.0
1.968GluTrp: 1.968 ± 0.0
3.608GluTyr: 3.608 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.624PheAla: 2.624 ± 0.0
0.984PheCys: 0.984 ± 0.0
3.936PheAsp: 3.936 ± 0.0
3.608PheGlu: 3.608 ± 0.0
1.64PhePhe: 1.64 ± 0.0
2.952PheGly: 2.952 ± 0.0
0.656PheHis: 0.656 ± 0.0
3.608PheIle: 3.608 ± 0.0
3.608PheLys: 3.608 ± 0.0
3.936PheLeu: 3.936 ± 0.0
1.312PheMet: 1.312 ± 0.0
3.28PheAsn: 3.28 ± 0.0
1.968PhePro: 1.968 ± 0.0
0.984PheGln: 0.984 ± 0.0
2.624PheArg: 2.624 ± 0.0
4.592PheSer: 4.592 ± 0.0
4.264PheThr: 4.264 ± 0.0
2.296PheVal: 2.296 ± 0.0
0.328PheTrp: 0.328 ± 0.0
1.968PheTyr: 1.968 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.968GlyAla: 1.968 ± 0.0
0.656GlyCys: 0.656 ± 0.0
2.952GlyAsp: 2.952 ± 0.0
2.296GlyGlu: 2.296 ± 0.0
1.312GlyPhe: 1.312 ± 0.0
2.952GlyGly: 2.952 ± 0.0
0.984GlyHis: 0.984 ± 0.0
3.608GlyIle: 3.608 ± 0.0
2.952GlyLys: 2.952 ± 0.0
6.56GlyLeu: 6.56 ± 0.0
2.296GlyMet: 2.296 ± 0.0
1.64GlyAsn: 1.64 ± 0.0
2.296GlyPro: 2.296 ± 0.0
1.64GlyGln: 1.64 ± 0.0
2.624GlyArg: 2.624 ± 0.0
2.952GlySer: 2.952 ± 0.0
2.624GlyThr: 2.624 ± 0.0
4.92GlyVal: 4.92 ± 0.0
0.328GlyTrp: 0.328 ± 0.0
3.608GlyTyr: 3.608 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.328HisAla: 0.328 ± 0.0
0.328HisCys: 0.328 ± 0.0
0.656HisAsp: 0.656 ± 0.0
0.984HisGlu: 0.984 ± 0.0
0.656HisPhe: 0.656 ± 0.0
1.64HisGly: 1.64 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.968HisIle: 1.968 ± 0.0
0.328HisLys: 0.328 ± 0.0
2.296HisLeu: 2.296 ± 0.0
0.984HisMet: 0.984 ± 0.0
0.984HisAsn: 0.984 ± 0.0
1.968HisPro: 1.968 ± 0.0
0.656HisGln: 0.656 ± 0.0
1.312HisArg: 1.312 ± 0.0
0.984HisSer: 0.984 ± 0.0
1.64HisThr: 1.64 ± 0.0
1.64HisVal: 1.64 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.656HisTyr: 0.656 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.592IleAla: 4.592 ± 0.0
1.64IleCys: 1.64 ± 0.0
2.624IleAsp: 2.624 ± 0.0
3.608IleGlu: 3.608 ± 0.0
3.28IlePhe: 3.28 ± 0.0
2.952IleGly: 2.952 ± 0.0
2.624IleHis: 2.624 ± 0.0
6.888IleIle: 6.888 ± 0.0
6.232IleLys: 6.232 ± 0.0
4.264IleLeu: 4.264 ± 0.0
2.296IleMet: 2.296 ± 0.0
4.264IleAsn: 4.264 ± 0.0
5.576IlePro: 5.576 ± 0.0
1.968IleGln: 1.968 ± 0.0
4.264IleArg: 4.264 ± 0.0
4.92IleSer: 4.92 ± 0.0
2.952IleThr: 2.952 ± 0.0
4.264IleVal: 4.264 ± 0.0
0.656IleTrp: 0.656 ± 0.0
3.936IleTyr: 3.936 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.984LysAla: 0.984 ± 0.0
1.312LysCys: 1.312 ± 0.0
4.264LysAsp: 4.264 ± 0.0
4.264LysGlu: 4.264 ± 0.0
3.28LysPhe: 3.28 ± 0.0
3.28LysGly: 3.28 ± 0.0
2.624LysHis: 2.624 ± 0.0
5.904LysIle: 5.904 ± 0.0
3.28LysLys: 3.28 ± 0.0
7.215LysLeu: 7.215 ± 0.0
1.312LysMet: 1.312 ± 0.0
1.64LysAsn: 1.64 ± 0.0
1.312LysPro: 1.312 ± 0.0
2.296LysGln: 2.296 ± 0.0
1.968LysArg: 1.968 ± 0.0
3.28LysSer: 3.28 ± 0.0
3.608LysThr: 3.608 ± 0.0
4.592LysVal: 4.592 ± 0.0
0.984LysTrp: 0.984 ± 0.0
2.624LysTyr: 2.624 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.592LeuAla: 4.592 ± 0.0
1.312LeuCys: 1.312 ± 0.0
6.56LeuAsp: 6.56 ± 0.0
6.232LeuGlu: 6.232 ± 0.0
3.936LeuPhe: 3.936 ± 0.0
4.264LeuGly: 4.264 ± 0.0
1.312LeuHis: 1.312 ± 0.0
3.936LeuIle: 3.936 ± 0.0
6.232LeuLys: 6.232 ± 0.0
5.576LeuLeu: 5.576 ± 0.0
0.656LeuMet: 0.656 ± 0.0
7.215LeuAsn: 7.215 ± 0.0
5.248LeuPro: 5.248 ± 0.0
2.624LeuGln: 2.624 ± 0.0
6.56LeuArg: 6.56 ± 0.0
7.543LeuSer: 7.543 ± 0.0
5.248LeuThr: 5.248 ± 0.0
6.56LeuVal: 6.56 ± 0.0
0.328LeuTrp: 0.328 ± 0.0
4.592LeuTyr: 4.592 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.296MetAla: 2.296 ± 0.0
0.656MetCys: 0.656 ± 0.0
1.64MetAsp: 1.64 ± 0.0
1.968MetGlu: 1.968 ± 0.0
1.64MetPhe: 1.64 ± 0.0
0.984MetGly: 0.984 ± 0.0
0.984MetHis: 0.984 ± 0.0
0.656MetIle: 0.656 ± 0.0
1.64MetLys: 1.64 ± 0.0
2.296MetLeu: 2.296 ± 0.0
0.656MetMet: 0.656 ± 0.0
0.984MetAsn: 0.984 ± 0.0
1.312MetPro: 1.312 ± 0.0
1.64MetGln: 1.64 ± 0.0
0.328MetArg: 0.328 ± 0.0
1.312MetSer: 1.312 ± 0.0
1.312MetThr: 1.312 ± 0.0
1.312MetVal: 1.312 ± 0.0
0.328MetTrp: 0.328 ± 0.0
1.968MetTyr: 1.968 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.624AsnAla: 2.624 ± 0.0
1.312AsnCys: 1.312 ± 0.0
1.312AsnAsp: 1.312 ± 0.0
2.952AsnGlu: 2.952 ± 0.0
1.968AsnPhe: 1.968 ± 0.0
0.984AsnGly: 0.984 ± 0.0
1.64AsnHis: 1.64 ± 0.0
3.936AsnIle: 3.936 ± 0.0
2.952AsnLys: 2.952 ± 0.0
5.248AsnLeu: 5.248 ± 0.0
1.968AsnMet: 1.968 ± 0.0
1.64AsnAsn: 1.64 ± 0.0
3.28AsnPro: 3.28 ± 0.0
1.968AsnGln: 1.968 ± 0.0
1.968AsnArg: 1.968 ± 0.0
4.264AsnSer: 4.264 ± 0.0
3.28AsnThr: 3.28 ± 0.0
5.576AsnVal: 5.576 ± 0.0
0.656AsnTrp: 0.656 ± 0.0
2.296AsnTyr: 2.296 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.296ProAla: 2.296 ± 0.0
0.984ProCys: 0.984 ± 0.0
1.968ProAsp: 1.968 ± 0.0
4.92ProGlu: 4.92 ± 0.0
3.608ProPhe: 3.608 ± 0.0
3.936ProGly: 3.936 ± 0.0
0.328ProHis: 0.328 ± 0.0
2.624ProIle: 2.624 ± 0.0
3.28ProLys: 3.28 ± 0.0
6.56ProLeu: 6.56 ± 0.0
1.64ProMet: 1.64 ± 0.0
2.296ProAsn: 2.296 ± 0.0
3.608ProPro: 3.608 ± 0.0
2.296ProGln: 2.296 ± 0.0
3.28ProArg: 3.28 ± 0.0
2.952ProSer: 2.952 ± 0.0
2.296ProThr: 2.296 ± 0.0
3.608ProVal: 3.608 ± 0.0
0.0ProTrp: 0.0 ± 0.0
2.296ProTyr: 2.296 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.984GlnAla: 0.984 ± 0.0
0.328GlnCys: 0.328 ± 0.0
2.296GlnAsp: 2.296 ± 0.0
1.312GlnGlu: 1.312 ± 0.0
3.608GlnPhe: 3.608 ± 0.0
1.312GlnGly: 1.312 ± 0.0
0.656GlnHis: 0.656 ± 0.0
2.952GlnIle: 2.952 ± 0.0
0.328GlnLys: 0.328 ± 0.0
2.296GlnLeu: 2.296 ± 0.0
0.656GlnMet: 0.656 ± 0.0
0.984GlnAsn: 0.984 ± 0.0
1.64GlnPro: 1.64 ± 0.0
1.312GlnGln: 1.312 ± 0.0
1.312GlnArg: 1.312 ± 0.0
0.984GlnSer: 0.984 ± 0.0
1.312GlnThr: 1.312 ± 0.0
2.952GlnVal: 2.952 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.312GlnTyr: 1.312 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.968ArgAla: 1.968 ± 0.0
0.656ArgCys: 0.656 ± 0.0
4.264ArgAsp: 4.264 ± 0.0
2.296ArgGlu: 2.296 ± 0.0
1.64ArgPhe: 1.64 ± 0.0
3.936ArgGly: 3.936 ± 0.0
0.656ArgHis: 0.656 ± 0.0
2.296ArgIle: 2.296 ± 0.0
2.296ArgLys: 2.296 ± 0.0
7.543ArgLeu: 7.543 ± 0.0
0.984ArgMet: 0.984 ± 0.0
1.312ArgAsn: 1.312 ± 0.0
3.936ArgPro: 3.936 ± 0.0
0.656ArgGln: 0.656 ± 0.0
1.64ArgArg: 1.64 ± 0.0
1.64ArgSer: 1.64 ± 0.0
2.952ArgThr: 2.952 ± 0.0
2.296ArgVal: 2.296 ± 0.0
1.64ArgTrp: 1.64 ± 0.0
2.952ArgTyr: 2.952 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
1.968SerAla: 1.968 ± 0.0
0.656SerCys: 0.656 ± 0.0
3.608SerAsp: 3.608 ± 0.0
3.936SerGlu: 3.936 ± 0.0
4.92SerPhe: 4.92 ± 0.0
3.936SerGly: 3.936 ± 0.0
1.64SerHis: 1.64 ± 0.0
4.264SerIle: 4.264 ± 0.0
5.904SerLys: 5.904 ± 0.0
7.543SerLeu: 7.543 ± 0.0
1.312SerMet: 1.312 ± 0.0
5.248SerAsn: 5.248 ± 0.0
2.296SerPro: 2.296 ± 0.0
1.64SerGln: 1.64 ± 0.0
2.952SerArg: 2.952 ± 0.0
6.888SerSer: 6.888 ± 0.0
6.232SerThr: 6.232 ± 0.0
2.296SerVal: 2.296 ± 0.0
1.968SerTrp: 1.968 ± 0.0
4.264SerTyr: 4.264 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.608ThrAla: 3.608 ± 0.0
0.656ThrCys: 0.656 ± 0.0
3.28ThrAsp: 3.28 ± 0.0
3.608ThrGlu: 3.608 ± 0.0
2.296ThrPhe: 2.296 ± 0.0
3.608ThrGly: 3.608 ± 0.0
0.656ThrHis: 0.656 ± 0.0
4.92ThrIle: 4.92 ± 0.0
3.28ThrLys: 3.28 ± 0.0
2.952ThrLeu: 2.952 ± 0.0
0.328ThrMet: 0.328 ± 0.0
2.952ThrAsn: 2.952 ± 0.0
2.624ThrPro: 2.624 ± 0.0
1.312ThrGln: 1.312 ± 0.0
1.64ThrArg: 1.64 ± 0.0
6.888ThrSer: 6.888 ± 0.0
1.968ThrThr: 1.968 ± 0.0
4.264ThrVal: 4.264 ± 0.0
0.656ThrTrp: 0.656 ± 0.0
3.28ThrTyr: 3.28 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.264ValAla: 4.264 ± 0.0
1.64ValCys: 1.64 ± 0.0
3.608ValAsp: 3.608 ± 0.0
3.936ValGlu: 3.936 ± 0.0
4.92ValPhe: 4.92 ± 0.0
1.968ValGly: 1.968 ± 0.0
0.656ValHis: 0.656 ± 0.0
5.248ValIle: 5.248 ± 0.0
2.952ValLys: 2.952 ± 0.0
3.936ValLeu: 3.936 ± 0.0
0.984ValMet: 0.984 ± 0.0
3.936ValAsn: 3.936 ± 0.0
5.576ValPro: 5.576 ± 0.0
2.624ValGln: 2.624 ± 0.0
3.28ValArg: 3.28 ± 0.0
5.904ValSer: 5.904 ± 0.0
3.28ValThr: 3.28 ± 0.0
4.592ValVal: 4.592 ± 0.0
0.656ValTrp: 0.656 ± 0.0
2.624ValTyr: 2.624 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.984TrpAla: 0.984 ± 0.0
0.328TrpCys: 0.328 ± 0.0
0.328TrpAsp: 0.328 ± 0.0
0.328TrpGlu: 0.328 ± 0.0
0.328TrpPhe: 0.328 ± 0.0
0.656TrpGly: 0.656 ± 0.0
0.328TrpHis: 0.328 ± 0.0
1.312TrpIle: 1.312 ± 0.0
1.312TrpLys: 1.312 ± 0.0
0.984TrpLeu: 0.984 ± 0.0
0.328TrpMet: 0.328 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.328TrpPro: 0.328 ± 0.0
0.328TrpGln: 0.328 ± 0.0
0.328TrpArg: 0.328 ± 0.0
0.656TrpSer: 0.656 ± 0.0
2.296TrpThr: 2.296 ± 0.0
1.64TrpVal: 1.64 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.656TrpTyr: 0.656 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.296TyrAla: 2.296 ± 0.0
0.984TyrCys: 0.984 ± 0.0
3.936TyrAsp: 3.936 ± 0.0
3.608TyrGlu: 3.608 ± 0.0
2.624TyrPhe: 2.624 ± 0.0
2.296TyrGly: 2.296 ± 0.0
1.312TyrHis: 1.312 ± 0.0
5.904TyrIle: 5.904 ± 0.0
2.296TyrLys: 2.296 ± 0.0
3.608TyrLeu: 3.608 ± 0.0
0.984TyrMet: 0.984 ± 0.0
4.264TyrAsn: 4.264 ± 0.0
1.64TyrPro: 1.64 ± 0.0
1.64TyrGln: 1.64 ± 0.0
3.28TyrArg: 3.28 ± 0.0
4.264TyrSer: 4.264 ± 0.0
1.64TyrThr: 1.64 ± 0.0
1.968TyrVal: 1.968 ± 0.0
0.328TyrTrp: 0.328 ± 0.0
4.92TyrTyr: 4.92 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3050 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski