Amino acid dipepetide frequency for Hubei sobemo-like virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.695AlaAla: 3.695 ± 1.849
1.232AlaCys: 1.232 ± 0.616
3.695AlaAsp: 3.695 ± 0.043
2.463AlaGlu: 2.463 ± 0.66
2.463AlaPhe: 2.463 ± 1.233
6.158AlaGly: 6.158 ± 0.703
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
2.463AlaLys: 2.463 ± 0.66
9.852AlaLeu: 9.852 ± 2.638
1.232AlaMet: 1.232 ± 1.276
2.463AlaAsn: 2.463 ± 0.66
3.695AlaPro: 3.695 ± 0.043
2.463AlaGln: 2.463 ± 2.552
3.695AlaArg: 3.695 ± 0.043
1.232AlaSer: 1.232 ± 0.616
2.463AlaThr: 2.463 ± 1.233
6.158AlaVal: 6.158 ± 2.595
1.232AlaTrp: 1.232 ± 0.616
3.695AlaTyr: 3.695 ± 1.849
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.232CysCys: 1.232 ± 0.616
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.232CysPhe: 1.232 ± 1.276
1.232CysGly: 1.232 ± 1.276
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.232CysLys: 1.232 ± 0.616
0.0CysLeu: 0.0 ± 0.0
2.463CysMet: 2.463 ± 1.233
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.232CysSer: 1.232 ± 0.616
0.0CysThr: 0.0 ± 0.0
1.232CysVal: 1.232 ± 1.276
1.232CysTrp: 1.232 ± 1.276
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.463AspAla: 2.463 ± 0.66
1.232AspCys: 1.232 ± 1.276
3.695AspAsp: 3.695 ± 1.936
2.463AspGlu: 2.463 ± 1.233
0.0AspPhe: 0.0 ± 0.0
2.463AspGly: 2.463 ± 0.66
1.232AspHis: 1.232 ± 0.616
2.463AspIle: 2.463 ± 1.233
3.695AspLys: 3.695 ± 1.936
3.695AspLeu: 3.695 ± 0.043
1.232AspMet: 1.232 ± 0.616
1.232AspAsn: 1.232 ± 1.276
1.232AspPro: 1.232 ± 0.616
3.695AspGln: 3.695 ± 0.043
3.695AspArg: 3.695 ± 1.936
3.695AspSer: 3.695 ± 1.936
3.695AspThr: 3.695 ± 1.936
3.695AspVal: 3.695 ± 3.828
2.463AspTrp: 2.463 ± 0.66
3.695AspTyr: 3.695 ± 0.043
0.0AspXaa: 0.0 ± 0.0
Glu
4.926GluAla: 4.926 ± 1.319
1.232GluCys: 1.232 ± 0.616
4.926GluAsp: 4.926 ± 0.573
2.463GluGlu: 2.463 ± 0.66
2.463GluPhe: 2.463 ± 2.552
3.695GluGly: 3.695 ± 1.849
2.463GluHis: 2.463 ± 0.66
1.232GluIle: 1.232 ± 0.616
2.463GluLys: 2.463 ± 1.233
6.158GluLeu: 6.158 ± 0.703
2.463GluMet: 2.463 ± 1.042
3.695GluAsn: 3.695 ± 1.849
4.926GluPro: 4.926 ± 0.573
1.232GluGln: 1.232 ± 0.616
2.463GluArg: 2.463 ± 2.552
4.926GluSer: 4.926 ± 2.466
4.926GluThr: 4.926 ± 0.573
0.0GluVal: 0.0 ± 0.0
1.232GluTrp: 1.232 ± 1.276
1.232GluTyr: 1.232 ± 1.276
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
2.463PheAsp: 2.463 ± 1.233
3.695PheGlu: 3.695 ± 1.936
0.0PhePhe: 0.0 ± 0.0
3.695PheGly: 3.695 ± 1.849
1.232PheHis: 1.232 ± 1.276
0.0PheIle: 0.0 ± 0.0
0.0PheLys: 0.0 ± 0.0
2.463PheLeu: 2.463 ± 0.66
1.232PheMet: 1.232 ± 1.276
1.232PheAsn: 1.232 ± 0.616
1.232PhePro: 1.232 ± 1.276
3.695PheGln: 3.695 ± 1.936
3.695PheArg: 3.695 ± 0.043
3.695PheSer: 3.695 ± 0.043
0.0PheThr: 0.0 ± 0.0
6.158PheVal: 6.158 ± 0.703
2.463PheTrp: 2.463 ± 0.66
2.463PheTyr: 2.463 ± 0.66
0.0PheXaa: 0.0 ± 0.0
Gly
6.158GlyAla: 6.158 ± 3.082
2.463GlyCys: 2.463 ± 2.552
2.463GlyAsp: 2.463 ± 0.66
6.158GlyGlu: 6.158 ± 1.19
2.463GlyPhe: 2.463 ± 0.66
6.158GlyGly: 6.158 ± 1.19
0.0GlyHis: 0.0 ± 0.0
1.232GlyIle: 1.232 ± 0.616
2.463GlyLys: 2.463 ± 0.66
3.695GlyLeu: 3.695 ± 1.849
2.463GlyMet: 2.463 ± 0.747
3.695GlyAsn: 3.695 ± 0.043
1.232GlyPro: 1.232 ± 1.276
2.463GlyGln: 2.463 ± 1.233
6.158GlyArg: 6.158 ± 1.19
6.158GlySer: 6.158 ± 3.082
7.389GlyThr: 7.389 ± 0.086
2.463GlyVal: 2.463 ± 0.66
2.463GlyTrp: 2.463 ± 2.552
3.695GlyTyr: 3.695 ± 0.043
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.232HisGlu: 1.232 ± 0.616
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.232HisIle: 1.232 ± 1.276
0.0HisLys: 0.0 ± 0.0
3.695HisLeu: 3.695 ± 0.043
1.232HisMet: 1.232 ± 1.276
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.232HisArg: 1.232 ± 1.276
2.463HisSer: 2.463 ± 1.233
0.0HisThr: 0.0 ± 0.0
3.695HisVal: 3.695 ± 0.043
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.695IleAla: 3.695 ± 1.849
0.0IleCys: 0.0 ± 0.0
1.232IleAsp: 1.232 ± 1.276
2.463IleGlu: 2.463 ± 2.552
0.0IlePhe: 0.0 ± 0.0
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.232IleLys: 1.232 ± 1.276
6.158IleLeu: 6.158 ± 3.082
1.232IleMet: 1.232 ± 0.616
1.232IleAsn: 1.232 ± 0.616
2.463IlePro: 2.463 ± 0.66
2.463IleGln: 2.463 ± 0.66
1.232IleArg: 1.232 ± 0.616
4.926IleSer: 4.926 ± 0.573
1.232IleThr: 1.232 ± 0.616
2.463IleVal: 2.463 ± 1.233
2.463IleTrp: 2.463 ± 0.66
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.232LysAla: 1.232 ± 1.276
0.0LysCys: 0.0 ± 0.0
2.463LysAsp: 2.463 ± 1.233
3.695LysGlu: 3.695 ± 1.936
1.232LysPhe: 1.232 ± 0.616
2.463LysGly: 2.463 ± 1.233
2.463LysHis: 2.463 ± 2.552
2.463LysIle: 2.463 ± 1.233
3.695LysLys: 3.695 ± 0.043
7.389LysLeu: 7.389 ± 0.086
0.0LysMet: 0.0 ± 0.0
2.463LysAsn: 2.463 ± 1.233
4.926LysPro: 4.926 ± 0.573
1.232LysGln: 1.232 ± 0.616
2.463LysArg: 2.463 ± 0.66
6.158LysSer: 6.158 ± 0.703
2.463LysThr: 2.463 ± 1.233
2.463LysVal: 2.463 ± 1.233
0.0LysTrp: 0.0 ± 0.0
2.463LysTyr: 2.463 ± 1.233
0.0LysXaa: 0.0 ± 0.0
Leu
7.389LeuAla: 7.389 ± 5.764
0.0LeuCys: 0.0 ± 0.0
4.926LeuAsp: 4.926 ± 0.573
4.926LeuGlu: 4.926 ± 0.573
4.926LeuPhe: 4.926 ± 3.212
13.547LeuGly: 13.547 ± 0.789
2.463LeuHis: 2.463 ± 0.66
3.695LeuIle: 3.695 ± 0.043
8.621LeuLys: 8.621 ± 1.362
12.315LeuLeu: 12.315 ± 7.083
3.695LeuMet: 3.695 ± 0.043
1.232LeuAsn: 1.232 ± 1.276
3.695LeuPro: 3.695 ± 0.043
3.695LeuGln: 3.695 ± 1.936
11.084LeuArg: 11.084 ± 1.763
13.547LeuSer: 13.547 ± 6.781
4.926LeuThr: 4.926 ± 1.319
2.463LeuVal: 2.463 ± 1.233
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
4.926MetAla: 4.926 ± 0.573
0.0MetCys: 0.0 ± 0.0
1.232MetAsp: 1.232 ± 1.276
0.0MetGlu: 0.0 ± 0.0
1.232MetPhe: 1.232 ± 0.616
2.463MetGly: 2.463 ± 0.66
1.232MetHis: 1.232 ± 0.616
0.0MetIle: 0.0 ± 0.0
1.232MetLys: 1.232 ± 1.276
1.232MetLeu: 1.232 ± 0.616
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.232MetPro: 1.232 ± 0.616
1.232MetGln: 1.232 ± 1.276
2.463MetArg: 2.463 ± 1.233
4.926MetSer: 4.926 ± 0.573
0.0MetThr: 0.0 ± 0.0
4.926MetVal: 4.926 ± 1.319
1.232MetTrp: 1.232 ± 0.616
2.463MetTyr: 2.463 ± 1.233
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
1.232AsnAsp: 1.232 ± 1.276
0.0AsnGlu: 0.0 ± 0.0
1.232AsnPhe: 1.232 ± 0.616
1.232AsnGly: 1.232 ± 0.616
0.0AsnHis: 0.0 ± 0.0
3.695AsnIle: 3.695 ± 1.849
1.232AsnLys: 1.232 ± 0.616
4.926AsnLeu: 4.926 ± 2.466
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.232AsnPro: 1.232 ± 0.616
1.232AsnGln: 1.232 ± 0.616
1.232AsnArg: 1.232 ± 0.616
3.695AsnSer: 3.695 ± 1.936
1.232AsnThr: 1.232 ± 0.616
2.463AsnVal: 2.463 ± 0.66
0.0AsnTrp: 0.0 ± 0.0
1.232AsnTyr: 1.232 ± 0.616
0.0AsnXaa: 0.0 ± 0.0
Pro
2.463ProAla: 2.463 ± 0.66
0.0ProCys: 0.0 ± 0.0
3.695ProAsp: 3.695 ± 1.936
1.232ProGlu: 1.232 ± 0.616
2.463ProPhe: 2.463 ± 1.233
3.695ProGly: 3.695 ± 0.043
0.0ProHis: 0.0 ± 0.0
4.926ProIle: 4.926 ± 0.573
2.463ProLys: 2.463 ± 1.233
4.926ProLeu: 4.926 ± 1.319
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
2.463ProPro: 2.463 ± 1.233
1.232ProGln: 1.232 ± 0.616
1.232ProArg: 1.232 ± 0.616
3.695ProSer: 3.695 ± 0.043
3.695ProThr: 3.695 ± 0.043
2.463ProVal: 2.463 ± 1.233
1.232ProTrp: 1.232 ± 0.616
2.463ProTyr: 2.463 ± 0.66
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.232GlnCys: 1.232 ± 0.616
3.695GlnAsp: 3.695 ± 0.043
4.926GlnGlu: 4.926 ± 0.573
1.232GlnPhe: 1.232 ± 1.276
2.463GlnGly: 2.463 ± 1.233
1.232GlnHis: 1.232 ± 0.616
3.695GlnIle: 3.695 ± 0.043
4.926GlnLys: 4.926 ± 0.573
6.158GlnLeu: 6.158 ± 0.703
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.695GlnPro: 3.695 ± 1.849
3.695GlnGln: 3.695 ± 1.936
1.232GlnArg: 1.232 ± 0.616
3.695GlnSer: 3.695 ± 1.936
3.695GlnThr: 3.695 ± 1.849
2.463GlnVal: 2.463 ± 1.233
1.232GlnTrp: 1.232 ± 0.616
1.232GlnTyr: 1.232 ± 1.276
0.0GlnXaa: 0.0 ± 0.0
Arg
4.926ArgAla: 4.926 ± 0.573
1.232ArgCys: 1.232 ± 0.616
3.695ArgAsp: 3.695 ± 0.043
2.463ArgGlu: 2.463 ± 0.66
4.926ArgPhe: 4.926 ± 1.319
1.232ArgGly: 1.232 ± 1.276
0.0ArgHis: 0.0 ± 0.0
2.463ArgIle: 2.463 ± 0.66
2.463ArgLys: 2.463 ± 1.233
8.621ArgLeu: 8.621 ± 1.362
1.232ArgMet: 1.232 ± 0.616
3.695ArgAsn: 3.695 ± 1.849
1.232ArgPro: 1.232 ± 0.616
6.158ArgGln: 6.158 ± 1.19
6.158ArgArg: 6.158 ± 0.703
6.158ArgSer: 6.158 ± 3.082
2.463ArgThr: 2.463 ± 1.233
3.695ArgVal: 3.695 ± 0.043
0.0ArgTrp: 0.0 ± 0.0
3.695ArgTyr: 3.695 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
1.232SerAla: 1.232 ± 0.616
1.232SerCys: 1.232 ± 1.276
4.926SerAsp: 4.926 ± 5.104
4.926SerGlu: 4.926 ± 2.466
4.926SerPhe: 4.926 ± 2.466
12.315SerGly: 12.315 ± 0.487
0.0SerHis: 0.0 ± 0.0
2.463SerIle: 2.463 ± 0.66
7.389SerLys: 7.389 ± 3.699
3.695SerLeu: 3.695 ± 0.043
3.695SerMet: 3.695 ± 1.849
2.463SerAsn: 2.463 ± 1.233
3.695SerPro: 3.695 ± 0.043
4.926SerGln: 4.926 ± 2.466
7.389SerArg: 7.389 ± 3.699
11.084SerSer: 11.084 ± 3.656
6.158SerThr: 6.158 ± 3.082
7.389SerVal: 7.389 ± 0.086
4.926SerTrp: 4.926 ± 1.319
1.232SerTyr: 1.232 ± 1.276
0.0SerXaa: 0.0 ± 0.0
Thr
4.926ThrAla: 4.926 ± 1.319
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
3.695ThrGlu: 3.695 ± 1.849
1.232ThrPhe: 1.232 ± 1.276
6.158ThrGly: 6.158 ± 1.19
0.0ThrHis: 0.0 ± 0.0
1.232ThrIle: 1.232 ± 1.276
1.232ThrLys: 1.232 ± 0.616
6.158ThrLeu: 6.158 ± 2.595
2.463ThrMet: 2.463 ± 0.66
1.232ThrAsn: 1.232 ± 0.616
2.463ThrPro: 2.463 ± 0.66
6.158ThrGln: 6.158 ± 3.082
2.463ThrArg: 2.463 ± 1.233
6.158ThrSer: 6.158 ± 1.19
2.463ThrThr: 2.463 ± 1.233
3.695ThrVal: 3.695 ± 1.849
0.0ThrTrp: 0.0 ± 0.0
2.463ThrTyr: 2.463 ± 1.233
0.0ThrXaa: 0.0 ± 0.0
Val
7.389ValAla: 7.389 ± 0.086
0.0ValCys: 0.0 ± 0.0
4.926ValAsp: 4.926 ± 3.212
7.389ValGlu: 7.389 ± 1.806
6.158ValPhe: 6.158 ± 2.595
2.463ValGly: 2.463 ± 0.66
0.0ValHis: 0.0 ± 0.0
2.463ValIle: 2.463 ± 0.66
2.463ValLys: 2.463 ± 0.66
6.158ValLeu: 6.158 ± 2.595
4.926ValMet: 4.926 ± 1.319
0.0ValAsn: 0.0 ± 0.0
4.926ValPro: 4.926 ± 0.573
3.695ValGln: 3.695 ± 1.849
4.926ValArg: 4.926 ± 2.466
4.926ValSer: 4.926 ± 0.573
2.463ValThr: 2.463 ± 1.233
3.695ValVal: 3.695 ± 0.043
0.0ValTrp: 0.0 ± 0.0
2.463ValTyr: 2.463 ± 0.66
0.0ValXaa: 0.0 ± 0.0
Trp
3.695TrpAla: 3.695 ± 1.936
0.0TrpCys: 0.0 ± 0.0
1.232TrpAsp: 1.232 ± 1.276
0.0TrpGlu: 0.0 ± 0.0
1.232TrpPhe: 1.232 ± 0.616
0.0TrpGly: 0.0 ± 0.0
1.232TrpHis: 1.232 ± 0.616
1.232TrpIle: 1.232 ± 0.616
0.0TrpLys: 0.0 ± 0.0
4.926TrpLeu: 4.926 ± 0.573
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.463TrpArg: 2.463 ± 0.66
1.232TrpSer: 1.232 ± 1.276
2.463TrpThr: 2.463 ± 2.552
2.463TrpVal: 2.463 ± 0.66
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.232TyrAla: 1.232 ± 0.616
0.0TyrCys: 0.0 ± 0.0
1.232TyrAsp: 1.232 ± 0.616
4.926TyrGlu: 4.926 ± 1.319
0.0TyrPhe: 0.0 ± 0.0
1.232TyrGly: 1.232 ± 0.616
1.232TyrHis: 1.232 ± 0.616
0.0TyrIle: 0.0 ± 0.0
2.463TyrLys: 2.463 ± 1.233
4.926TyrLeu: 4.926 ± 1.319
1.232TyrMet: 1.232 ± 0.616
1.232TyrAsn: 1.232 ± 0.616
0.0TyrPro: 0.0 ± 0.0
1.232TyrGln: 1.232 ± 0.616
1.232TyrArg: 1.232 ± 1.276
2.463TyrSer: 2.463 ± 0.66
2.463TyrThr: 2.463 ± 0.66
7.389TyrVal: 7.389 ± 0.086
0.0TyrTrp: 0.0 ± 0.0
1.232TyrTyr: 1.232 ± 0.616
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (813 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski