Amino acid dipepetide frequency for Beihai paphia shell virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.174AlaAla: 5.174 ± 0.647
0.69AlaCys: 0.69 ± 0.196
4.484AlaAsp: 4.484 ± 0.451
3.794AlaGlu: 3.794 ± 0.255
3.105AlaPhe: 3.105 ± 0.489
3.794AlaGly: 3.794 ± 0.841
1.725AlaHis: 1.725 ± 0.881
5.174AlaIle: 5.174 ± 0.998
1.725AlaLys: 1.725 ± 0.216
4.139AlaLeu: 4.139 ± 0.627
2.07AlaMet: 2.07 ± 0.785
3.794AlaAsn: 3.794 ± 2.448
2.415AlaPro: 2.415 ± 0.96
2.07AlaGln: 2.07 ± 1.057
3.105AlaArg: 3.105 ± 1.156
4.139AlaSer: 4.139 ± 0.079
3.794AlaThr: 3.794 ± 0.803
4.139AlaVal: 4.139 ± 0.469
1.035AlaTrp: 1.035 ± 0.02
1.38AlaTyr: 1.38 ± 0.156
0.0AlaXaa: 0.0 ± 0.0
Cys
1.035CysAla: 1.035 ± 0.02
0.345CysCys: 0.345 ± 0.176
0.69CysAsp: 0.69 ± 0.352
1.38CysGlu: 1.38 ± 0.156
2.415CysPhe: 2.415 ± 1.233
3.449CysGly: 3.449 ± 1.761
0.345CysHis: 0.345 ± 0.176
1.035CysIle: 1.035 ± 0.02
0.345CysLys: 0.345 ± 0.176
1.725CysLeu: 1.725 ± 0.881
0.69CysMet: 0.69 ± 0.352
0.345CysAsn: 0.345 ± 0.176
1.035CysPro: 1.035 ± 0.02
0.69CysGln: 0.69 ± 0.196
1.035CysArg: 1.035 ± 0.02
1.38CysSer: 1.38 ± 0.156
0.345CysThr: 0.345 ± 0.176
1.38CysVal: 1.38 ± 0.705
0.345CysTrp: 0.345 ± 0.372
1.035CysTyr: 1.035 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
4.484AspAla: 4.484 ± 0.451
1.035AspCys: 1.035 ± 0.528
3.794AspAsp: 3.794 ± 0.841
1.38AspGlu: 1.38 ± 0.392
4.484AspPhe: 4.484 ± 0.645
1.38AspGly: 1.38 ± 0.156
1.035AspHis: 1.035 ± 0.568
4.829AspIle: 4.829 ± 0.273
3.105AspLys: 3.105 ± 1.037
5.864AspLeu: 5.864 ± 0.843
0.69AspMet: 0.69 ± 0.352
3.105AspAsn: 3.105 ± 0.607
3.449AspPro: 3.449 ± 1.528
1.38AspGln: 1.38 ± 0.392
3.105AspArg: 3.105 ± 1.585
3.105AspSer: 3.105 ± 0.059
1.725AspThr: 1.725 ± 0.216
4.139AspVal: 4.139 ± 0.469
0.69AspTrp: 0.69 ± 0.352
2.76AspTyr: 2.76 ± 0.861
0.0AspXaa: 0.0 ± 0.0
Glu
2.415GluAla: 2.415 ± 0.412
1.38GluCys: 1.38 ± 0.705
3.105GluAsp: 3.105 ± 0.607
6.209GluGlu: 6.209 ± 0.978
3.105GluPhe: 3.105 ± 0.489
3.449GluGly: 3.449 ± 1.213
1.725GluHis: 1.725 ± 0.881
6.209GluIle: 6.209 ± 1.763
2.07GluLys: 2.07 ± 0.509
5.864GluLeu: 5.864 ± 0.295
1.035GluMet: 1.035 ± 0.568
1.38GluAsn: 1.38 ± 0.392
3.105GluPro: 3.105 ± 0.059
1.035GluGln: 1.035 ± 0.02
2.76GluArg: 2.76 ± 1.409
3.449GluSer: 3.449 ± 0.117
2.07GluThr: 2.07 ± 0.509
4.139GluVal: 4.139 ± 0.079
1.38GluTrp: 1.38 ± 0.156
1.38GluTyr: 1.38 ± 0.156
0.0GluXaa: 0.0 ± 0.0
Phe
2.76PheAla: 2.76 ± 0.235
0.345PheCys: 0.345 ± 0.176
3.794PheAsp: 3.794 ± 1.351
4.829PheGlu: 4.829 ± 0.275
3.105PhePhe: 3.105 ± 0.059
3.794PheGly: 3.794 ± 0.293
2.07PheHis: 2.07 ± 0.588
1.725PheIle: 1.725 ± 0.333
1.725PheLys: 1.725 ± 0.333
4.829PheLeu: 4.829 ± 0.821
2.07PheMet: 2.07 ± 1.057
2.07PheAsn: 2.07 ± 0.588
2.76PhePro: 2.76 ± 0.784
2.76PheGln: 2.76 ± 1.332
3.449PheArg: 3.449 ± 0.117
3.794PheSer: 3.794 ± 0.255
4.139PheThr: 4.139 ± 0.469
3.105PheVal: 3.105 ± 0.607
0.345PheTrp: 0.345 ± 0.176
1.725PheTyr: 1.725 ± 0.333
0.0PheXaa: 0.0 ± 0.0
Gly
2.07GlyAla: 2.07 ± 0.04
1.38GlyCys: 1.38 ± 0.156
4.484GlyAsp: 4.484 ± 1.193
4.484GlyGlu: 4.484 ± 1.547
2.76GlyPhe: 2.76 ± 0.313
2.415GlyGly: 2.415 ± 0.685
1.035GlyHis: 1.035 ± 0.568
2.415GlyIle: 2.415 ± 0.137
6.209GlyLys: 6.209 ± 1.526
4.484GlyLeu: 4.484 ± 1.193
2.76GlyMet: 2.76 ± 0.313
2.415GlyAsn: 2.415 ± 0.96
2.76GlyPro: 2.76 ± 2.428
1.725GlyGln: 1.725 ± 0.333
2.76GlyArg: 2.76 ± 0.784
5.864GlySer: 5.864 ± 0.253
3.449GlyThr: 3.449 ± 0.979
4.829GlyVal: 4.829 ± 1.371
0.69GlyTrp: 0.69 ± 0.352
1.725GlyTyr: 1.725 ± 0.216
0.0GlyXaa: 0.0 ± 0.0
His
1.38HisAla: 1.38 ± 0.94
0.69HisCys: 0.69 ± 0.352
1.725HisAsp: 1.725 ± 0.333
0.0HisGlu: 0.0 ± 0.0
1.725HisPhe: 1.725 ± 0.216
1.035HisGly: 1.035 ± 0.528
0.0HisHis: 0.0 ± 0.0
1.725HisIle: 1.725 ± 0.333
1.38HisLys: 1.38 ± 0.392
1.725HisLeu: 1.725 ± 0.881
0.345HisMet: 0.345 ± 0.176
0.0HisAsn: 0.0 ± 0.0
1.38HisPro: 1.38 ± 0.392
0.345HisGln: 0.345 ± 0.176
1.035HisArg: 1.035 ± 0.568
2.76HisSer: 2.76 ± 0.861
1.38HisThr: 1.38 ± 0.705
1.38HisVal: 1.38 ± 0.705
0.69HisTrp: 0.69 ± 0.744
0.69HisTyr: 0.69 ± 0.196
0.0HisXaa: 0.0 ± 0.0
Ile
6.209IleAla: 6.209 ± 0.667
1.38IleCys: 1.38 ± 0.156
3.105IleAsp: 3.105 ± 1.037
4.139IleGlu: 4.139 ± 0.627
3.794IlePhe: 3.794 ± 0.293
4.829IleGly: 4.829 ± 2.468
0.345IleHis: 0.345 ± 0.176
3.105IleIle: 3.105 ± 1.037
1.38IleLys: 1.38 ± 0.156
5.864IleLeu: 5.864 ± 1.898
1.725IleMet: 1.725 ± 0.333
4.139IleAsn: 4.139 ± 0.079
3.449IlePro: 3.449 ± 0.665
1.725IleGln: 1.725 ± 0.881
4.139IleArg: 4.139 ± 0.469
3.794IleSer: 3.794 ± 0.293
3.794IleThr: 3.794 ± 0.293
3.794IleVal: 3.794 ± 0.803
1.38IleTrp: 1.38 ± 0.156
1.725IleTyr: 1.725 ± 0.333
0.0IleXaa: 0.0 ± 0.0
Lys
2.415LysAla: 2.415 ± 0.685
2.76LysCys: 2.76 ± 0.861
2.76LysAsp: 2.76 ± 0.861
2.76LysGlu: 2.76 ± 1.409
2.415LysPhe: 2.415 ± 0.412
5.174LysGly: 5.174 ± 0.099
1.725LysHis: 1.725 ± 0.216
3.449LysIle: 3.449 ± 0.979
3.449LysLys: 3.449 ± 0.665
4.139LysLeu: 4.139 ± 0.079
2.07LysMet: 2.07 ± 1.057
0.69LysAsn: 0.69 ± 0.196
1.725LysPro: 1.725 ± 0.216
2.76LysGln: 2.76 ± 0.313
4.139LysArg: 4.139 ± 0.469
1.725LysSer: 1.725 ± 0.881
2.76LysThr: 2.76 ± 0.313
3.794LysVal: 3.794 ± 0.293
1.38LysTrp: 1.38 ± 0.705
2.76LysTyr: 2.76 ± 0.861
0.0LysXaa: 0.0 ± 0.0
Leu
4.484LeuAla: 4.484 ± 1.193
1.725LeuCys: 1.725 ± 0.881
4.139LeuAsp: 4.139 ± 1.175
4.139LeuGlu: 4.139 ± 1.017
4.139LeuPhe: 4.139 ± 1.017
3.449LeuGly: 3.449 ± 0.665
1.38LeuHis: 1.38 ± 0.156
5.519LeuIle: 5.519 ± 1.722
7.244LeuLys: 7.244 ± 1.783
5.864LeuLeu: 5.864 ± 0.802
0.69LeuMet: 0.69 ± 0.352
3.794LeuAsn: 3.794 ± 1.351
5.519LeuPro: 5.519 ± 1.019
2.76LeuGln: 2.76 ± 1.409
6.209LeuArg: 6.209 ± 2.074
5.864LeuSer: 5.864 ± 0.802
9.314LeuThr: 9.314 ± 0.178
4.484LeuVal: 4.484 ± 1.193
2.07LeuTrp: 2.07 ± 0.588
2.07LeuTyr: 2.07 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
2.415MetAla: 2.415 ± 0.412
0.69MetCys: 0.69 ± 0.352
1.035MetAsp: 1.035 ± 0.02
0.345MetGlu: 0.345 ± 0.176
0.345MetPhe: 0.345 ± 0.372
1.725MetGly: 1.725 ± 0.764
0.0MetHis: 0.0 ± 0.0
1.38MetIle: 1.38 ± 0.705
3.794MetLys: 3.794 ± 0.841
1.38MetLeu: 1.38 ± 0.392
0.0MetMet: 0.0 ± 0.0
1.725MetAsn: 1.725 ± 0.333
1.725MetPro: 1.725 ± 0.333
0.69MetGln: 0.69 ± 0.196
0.69MetArg: 0.69 ± 0.196
2.07MetSer: 2.07 ± 0.509
1.035MetThr: 1.035 ± 0.02
1.38MetVal: 1.38 ± 0.705
0.0MetTrp: 0.0 ± 0.0
2.07MetTyr: 2.07 ± 1.136
0.0MetXaa: 0.0 ± 0.0
Asn
4.484AsnAla: 4.484 ± 0.097
1.035AsnCys: 1.035 ± 0.02
2.415AsnAsp: 2.415 ± 0.137
3.105AsnGlu: 3.105 ± 1.037
2.76AsnPhe: 2.76 ± 1.332
4.139AsnGly: 4.139 ± 1.724
0.345AsnHis: 0.345 ± 0.176
1.38AsnIle: 1.38 ± 0.392
2.76AsnLys: 2.76 ± 0.784
3.794AsnLeu: 3.794 ± 0.841
0.345AsnMet: 0.345 ± 0.372
2.76AsnAsn: 2.76 ± 0.313
3.105AsnPro: 3.105 ± 1.156
1.38AsnGln: 1.38 ± 0.392
1.725AsnArg: 1.725 ± 0.216
2.76AsnSer: 2.76 ± 1.332
3.105AsnThr: 3.105 ± 2.252
3.449AsnVal: 3.449 ± 1.528
1.035AsnTrp: 1.035 ± 0.02
1.725AsnTyr: 1.725 ± 1.312
0.0AsnXaa: 0.0 ± 0.0
Pro
2.76ProAla: 2.76 ± 0.235
0.345ProCys: 0.345 ± 0.372
2.07ProAsp: 2.07 ± 0.588
3.449ProGlu: 3.449 ± 0.117
3.105ProPhe: 3.105 ± 1.704
3.105ProGly: 3.105 ± 1.156
1.725ProHis: 1.725 ± 0.333
3.449ProIle: 3.449 ± 0.665
2.07ProLys: 2.07 ± 0.509
3.105ProLeu: 3.105 ± 0.489
1.725ProMet: 1.725 ± 0.276
2.07ProAsn: 2.07 ± 1.136
2.415ProPro: 2.415 ± 1.508
2.07ProGln: 2.07 ± 1.684
2.415ProArg: 2.415 ± 0.96
2.07ProSer: 2.07 ± 1.136
4.484ProThr: 4.484 ± 0.097
2.07ProVal: 2.07 ± 0.588
1.725ProTrp: 1.725 ± 0.216
2.76ProTyr: 2.76 ± 1.332
0.0ProXaa: 0.0 ± 0.0
Gln
3.105GlnAla: 3.105 ± 0.607
0.345GlnCys: 0.345 ± 0.372
2.07GlnAsp: 2.07 ± 0.04
1.035GlnGlu: 1.035 ± 0.02
1.035GlnPhe: 1.035 ± 0.02
0.69GlnGly: 0.69 ± 0.196
1.38GlnHis: 1.38 ± 0.392
2.415GlnIle: 2.415 ± 0.412
2.415GlnLys: 2.415 ± 1.233
2.415GlnLeu: 2.415 ± 0.685
0.69GlnMet: 0.69 ± 0.352
1.725GlnAsn: 1.725 ± 0.216
0.69GlnPro: 0.69 ± 0.196
2.07GlnGln: 2.07 ± 0.588
1.38GlnArg: 1.38 ± 0.156
4.829GlnSer: 4.829 ± 1.371
1.035GlnThr: 1.035 ± 0.02
2.07GlnVal: 2.07 ± 1.057
0.69GlnTrp: 0.69 ± 0.196
2.07GlnTyr: 2.07 ± 0.04
0.0GlnXaa: 0.0 ± 0.0
Arg
2.76ArgAla: 2.76 ± 0.313
1.035ArgCys: 1.035 ± 0.528
2.415ArgAsp: 2.415 ± 1.233
3.105ArgGlu: 3.105 ± 0.489
2.07ArgPhe: 2.07 ± 1.136
3.449ArgGly: 3.449 ± 0.431
1.38ArgHis: 1.38 ± 0.156
3.794ArgIle: 3.794 ± 0.841
2.07ArgLys: 2.07 ± 0.509
3.449ArgLeu: 3.449 ± 0.431
1.725ArgMet: 1.725 ± 0.216
2.07ArgAsn: 2.07 ± 0.04
1.725ArgPro: 1.725 ± 0.764
1.035ArgGln: 1.035 ± 0.528
3.449ArgArg: 3.449 ± 1.761
3.105ArgSer: 3.105 ± 0.059
2.76ArgThr: 2.76 ± 0.313
4.829ArgVal: 4.829 ± 1.37
2.415ArgTrp: 2.415 ± 0.137
3.449ArgTyr: 3.449 ± 0.431
0.0ArgXaa: 0.0 ± 0.0
Ser
3.105SerAla: 3.105 ± 0.489
2.07SerCys: 2.07 ± 1.057
4.139SerAsp: 4.139 ± 0.469
2.415SerGlu: 2.415 ± 0.412
3.449SerPhe: 3.449 ± 0.117
4.829SerGly: 4.829 ± 1.371
1.035SerHis: 1.035 ± 0.528
3.105SerIle: 3.105 ± 0.059
4.484SerLys: 4.484 ± 1.742
8.969SerLeu: 8.969 ± 0.742
2.76SerMet: 2.76 ± 1.332
2.76SerAsn: 2.76 ± 0.784
2.76SerPro: 2.76 ± 0.235
3.794SerGln: 3.794 ± 1.351
2.415SerArg: 2.415 ± 0.412
6.899SerSer: 6.899 ± 1.33
4.829SerThr: 4.829 ± 0.823
5.174SerVal: 5.174 ± 0.099
1.725SerTrp: 1.725 ± 0.764
2.415SerTyr: 2.415 ± 0.96
0.0SerXaa: 0.0 ± 0.0
Thr
3.449ThrAla: 3.449 ± 0.979
0.69ThrCys: 0.69 ± 0.352
1.035ThrAsp: 1.035 ± 0.02
3.794ThrGlu: 3.794 ± 0.293
2.76ThrPhe: 2.76 ± 0.313
3.105ThrGly: 3.105 ± 0.607
2.07ThrHis: 2.07 ± 0.509
5.864ThrIle: 5.864 ± 0.295
2.07ThrLys: 2.07 ± 0.509
4.484ThrLeu: 4.484 ± 0.451
1.035ThrMet: 1.035 ± 0.568
4.484ThrAsn: 4.484 ± 0.999
3.794ThrPro: 3.794 ± 0.255
2.07ThrGln: 2.07 ± 1.057
2.415ThrArg: 2.415 ± 0.137
5.864ThrSer: 5.864 ± 1.939
4.484ThrThr: 4.484 ± 2.644
3.105ThrVal: 3.105 ± 0.489
0.345ThrTrp: 0.345 ± 0.176
3.105ThrTyr: 3.105 ± 0.059
0.0ThrXaa: 0.0 ± 0.0
Val
3.105ValAla: 3.105 ± 0.607
2.07ValCys: 2.07 ± 0.509
5.519ValAsp: 5.519 ± 0.471
2.07ValGlu: 2.07 ± 0.509
3.794ValPhe: 3.794 ± 0.255
3.794ValGly: 3.794 ± 0.255
0.69ValHis: 0.69 ± 0.352
4.484ValIle: 4.484 ± 0.097
3.105ValLys: 3.105 ± 1.037
5.519ValLeu: 5.519 ± 0.625
0.69ValMet: 0.69 ± 0.196
4.829ValAsn: 4.829 ± 0.821
3.449ValPro: 3.449 ± 0.431
2.76ValGln: 2.76 ± 1.332
3.105ValArg: 3.105 ± 0.489
5.174ValSer: 5.174 ± 0.099
2.07ValThr: 2.07 ± 0.509
4.484ValVal: 4.484 ± 0.097
0.69ValTrp: 0.69 ± 0.352
2.415ValTyr: 2.415 ± 0.685
0.0ValXaa: 0.0 ± 0.0
Trp
1.725TrpAla: 1.725 ± 0.216
0.0TrpCys: 0.0 ± 0.0
0.345TrpAsp: 0.345 ± 0.372
2.76TrpGlu: 2.76 ± 0.235
1.38TrpPhe: 1.38 ± 0.156
0.345TrpGly: 0.345 ± 0.176
0.69TrpHis: 0.69 ± 0.196
1.38TrpIle: 1.38 ± 0.156
1.725TrpLys: 1.725 ± 0.333
2.07TrpLeu: 2.07 ± 1.057
0.0TrpMet: 0.0 ± 0.0
1.38TrpAsn: 1.38 ± 1.488
0.0TrpPro: 0.0 ± 0.0
0.345TrpGln: 0.345 ± 0.176
1.035TrpArg: 1.035 ± 0.528
2.415TrpSer: 2.415 ± 0.412
0.345TrpThr: 0.345 ± 0.176
0.69TrpVal: 0.69 ± 0.196
0.69TrpTrp: 0.69 ± 0.352
0.69TrpTyr: 0.69 ± 0.352
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.76TyrAla: 2.76 ± 0.235
1.035TyrCys: 1.035 ± 0.02
2.415TyrAsp: 2.415 ± 0.685
2.07TyrGlu: 2.07 ± 0.509
3.449TyrPhe: 3.449 ± 1.528
2.76TyrGly: 2.76 ± 0.313
0.69TyrHis: 0.69 ± 0.196
1.38TyrIle: 1.38 ± 0.156
1.725TyrLys: 1.725 ± 0.764
5.174TyrLeu: 5.174 ± 0.647
1.035TyrMet: 1.035 ± 0.02
2.07TyrAsn: 2.07 ± 0.588
1.725TyrPro: 1.725 ± 0.881
0.69TyrGln: 0.69 ± 0.352
1.725TyrArg: 1.725 ± 0.216
2.07TyrSer: 2.07 ± 0.588
3.105TyrThr: 3.105 ± 0.607
1.38TyrVal: 1.38 ± 0.156
0.69TyrTrp: 0.69 ± 0.352
1.38TyrTyr: 1.38 ± 0.705
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2900 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski