Amino acid dipepetide frequency for Beihai sesarmid crab virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.963AlaAla: 12.963 ± 2.199
3.241AlaCys: 3.241 ± 1.056
2.778AlaAsp: 2.778 ± 1.297
4.63AlaGlu: 4.63 ± 1.692
4.63AlaPhe: 4.63 ± 0.877
6.481AlaGly: 6.481 ± 0.457
2.778AlaHis: 2.778 ± 0.012
7.407AlaIle: 7.407 ± 1.679
7.407AlaLys: 7.407 ± 1.679
7.87AlaLeu: 7.87 ± 1.106
2.778AlaMet: 2.778 ± 1.272
2.778AlaAsn: 2.778 ± 0.012
6.481AlaPro: 6.481 ± 1.742
3.241AlaGln: 3.241 ± 0.229
5.093AlaArg: 5.093 ± 1.093
4.167AlaSer: 4.167 ± 0.661
4.167AlaThr: 4.167 ± 0.661
5.093AlaVal: 5.093 ± 1.476
0.926AlaTrp: 0.926 ± 0.432
5.093AlaTyr: 5.093 ± 2.378
0.0AlaXaa: 0.0 ± 0.0
Cys
1.389CysAla: 1.389 ± 0.649
0.463CysCys: 0.463 ± 0.216
1.852CysAsp: 1.852 ± 0.865
1.389CysGlu: 1.389 ± 0.649
0.463CysPhe: 0.463 ± 0.216
0.463CysGly: 0.463 ± 0.216
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.389CysLys: 1.389 ± 0.649
2.315CysLeu: 2.315 ± 0.204
0.463CysMet: 0.463 ± 0.216
1.389CysAsn: 1.389 ± 0.649
0.926CysPro: 0.926 ± 0.432
0.926CysGln: 0.926 ± 0.852
0.463CysArg: 0.463 ± 0.216
0.926CysSer: 0.926 ± 0.432
1.389CysThr: 1.389 ± 0.649
2.778CysVal: 2.778 ± 1.297
0.463CysTrp: 0.463 ± 0.216
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.481AspAla: 6.481 ± 0.827
1.852AspCys: 1.852 ± 0.865
5.556AspAsp: 5.556 ± 0.025
3.704AspGlu: 3.704 ± 0.84
0.926AspPhe: 0.926 ± 0.432
3.704AspGly: 3.704 ± 0.445
0.926AspHis: 0.926 ± 0.432
7.407AspIle: 7.407 ± 2.964
5.556AspLys: 5.556 ± 1.26
4.167AspLeu: 4.167 ± 1.946
0.926AspMet: 0.926 ± 0.852
2.315AspAsn: 2.315 ± 0.204
3.704AspPro: 3.704 ± 0.84
2.315AspGln: 2.315 ± 0.204
6.019AspArg: 6.019 ± 1.526
4.63AspSer: 4.63 ± 0.877
4.63AspThr: 4.63 ± 0.877
3.704AspVal: 3.704 ± 3.409
0.926AspTrp: 0.926 ± 0.432
1.389AspTyr: 1.389 ± 0.636
0.0AspXaa: 0.0 ± 0.0
Glu
3.241GluAla: 3.241 ± 0.229
0.463GluCys: 0.463 ± 0.216
3.241GluAsp: 3.241 ± 1.056
1.389GluGlu: 1.389 ± 0.649
5.093GluPhe: 5.093 ± 1.093
1.852GluGly: 1.852 ± 0.865
0.926GluHis: 0.926 ± 0.852
4.167GluIle: 4.167 ± 0.624
2.315GluLys: 2.315 ± 1.081
4.167GluLeu: 4.167 ± 0.661
1.389GluMet: 1.389 ± 0.636
1.852GluAsn: 1.852 ± 0.42
1.852GluPro: 1.852 ± 0.865
2.778GluGln: 2.778 ± 1.297
2.315GluArg: 2.315 ± 1.081
2.315GluSer: 2.315 ± 0.204
2.778GluThr: 2.778 ± 1.297
2.315GluVal: 2.315 ± 1.081
0.0GluTrp: 0.0 ± 0.0
1.852GluTyr: 1.852 ± 0.865
0.0GluXaa: 0.0 ± 0.0
Phe
4.63PheAla: 4.63 ± 1.692
1.852PheCys: 1.852 ± 0.865
3.704PheAsp: 3.704 ± 1.729
2.778PheGlu: 2.778 ± 1.297
2.315PhePhe: 2.315 ± 1.488
3.241PheGly: 3.241 ± 0.229
1.852PheHis: 1.852 ± 0.42
2.315PheIle: 2.315 ± 1.488
2.315PheLys: 2.315 ± 1.081
2.315PheLeu: 2.315 ± 0.204
0.926PheMet: 0.926 ± 0.432
3.241PheAsn: 3.241 ± 0.229
1.852PhePro: 1.852 ± 0.42
0.926PheGln: 0.926 ± 0.852
1.852PheArg: 1.852 ± 0.42
3.704PheSer: 3.704 ± 1.729
4.63PheThr: 4.63 ± 1.692
2.315PheVal: 2.315 ± 0.204
0.463PheTrp: 0.463 ± 0.216
0.463PheTyr: 0.463 ± 0.216
0.0PheXaa: 0.0 ± 0.0
Gly
2.315GlyAla: 2.315 ± 1.488
0.926GlyCys: 0.926 ± 0.432
3.241GlyAsp: 3.241 ± 0.229
2.315GlyGlu: 2.315 ± 1.081
2.315GlyPhe: 2.315 ± 0.204
3.704GlyGly: 3.704 ± 0.84
0.926GlyHis: 0.926 ± 0.852
3.241GlyIle: 3.241 ± 1.513
4.63GlyLys: 4.63 ± 0.407
3.704GlyLeu: 3.704 ± 0.84
1.852GlyMet: 1.852 ± 0.865
2.778GlyAsn: 2.778 ± 0.012
0.463GlyPro: 0.463 ± 0.216
0.463GlyGln: 0.463 ± 1.068
3.241GlyArg: 3.241 ± 1.513
5.556GlySer: 5.556 ± 2.544
4.167GlyThr: 4.167 ± 3.193
4.63GlyVal: 4.63 ± 1.692
0.463GlyTrp: 0.463 ± 0.216
3.704GlyTyr: 3.704 ± 0.445
0.0GlyXaa: 0.0 ± 0.0
His
3.241HisAla: 3.241 ± 0.229
0.0HisCys: 0.0 ± 0.0
0.926HisAsp: 0.926 ± 0.432
0.463HisGlu: 0.463 ± 0.216
0.926HisPhe: 0.926 ± 0.432
1.389HisGly: 1.389 ± 0.649
2.315HisHis: 2.315 ± 1.488
1.852HisIle: 1.852 ± 0.42
0.463HisLys: 0.463 ± 0.216
2.315HisLeu: 2.315 ± 0.204
2.315HisMet: 2.315 ± 0.204
0.926HisAsn: 0.926 ± 0.432
0.926HisPro: 0.926 ± 0.852
1.389HisGln: 1.389 ± 0.636
0.463HisArg: 0.463 ± 0.216
0.463HisSer: 0.463 ± 0.216
1.389HisThr: 1.389 ± 0.636
3.704HisVal: 3.704 ± 2.124
0.926HisTrp: 0.926 ± 0.852
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
9.259IleAla: 9.259 ± 3.039
0.926IleCys: 0.926 ± 0.432
6.944IleAsp: 6.944 ± 1.896
3.241IleGlu: 3.241 ± 0.229
3.241IlePhe: 3.241 ± 3.625
4.167IleGly: 4.167 ± 1.908
0.0IleHis: 0.0 ± 0.0
4.63IleIle: 4.63 ± 4.261
3.704IleLys: 3.704 ± 3.409
3.241IleLeu: 3.241 ± 0.229
0.463IleMet: 0.463 ± 0.216
0.926IleAsn: 0.926 ± 0.432
2.778IlePro: 2.778 ± 0.012
2.315IleGln: 2.315 ± 1.081
4.63IleArg: 4.63 ± 2.162
2.778IleSer: 2.778 ± 2.557
5.556IleThr: 5.556 ± 2.544
3.241IleVal: 3.241 ± 0.229
0.0IleTrp: 0.0 ± 0.0
4.167IleTyr: 4.167 ± 0.624
0.0IleXaa: 0.0 ± 0.0
Lys
3.704LysAla: 3.704 ± 0.445
1.389LysCys: 1.389 ± 0.649
3.704LysAsp: 3.704 ± 0.445
3.704LysGlu: 3.704 ± 0.84
5.093LysPhe: 5.093 ± 2.378
3.241LysGly: 3.241 ± 0.229
2.778LysHis: 2.778 ± 1.272
5.556LysIle: 5.556 ± 2.544
2.778LysLys: 2.778 ± 0.012
6.944LysLeu: 6.944 ± 1.896
1.852LysMet: 1.852 ± 0.42
1.389LysAsn: 1.389 ± 0.649
1.389LysPro: 1.389 ± 0.636
1.389LysGln: 1.389 ± 0.649
3.241LysArg: 3.241 ± 0.229
3.241LysSer: 3.241 ± 2.34
4.167LysThr: 4.167 ± 1.946
6.481LysVal: 6.481 ± 0.827
0.0LysTrp: 0.0 ± 0.0
2.315LysTyr: 2.315 ± 1.081
0.0LysXaa: 0.0 ± 0.0
Leu
10.185LeuAla: 10.185 ± 0.902
0.463LeuCys: 0.463 ± 0.216
8.796LeuAsp: 8.796 ± 0.254
3.241LeuGlu: 3.241 ± 0.229
1.389LeuPhe: 1.389 ± 0.636
4.63LeuGly: 4.63 ± 0.407
0.926LeuHis: 0.926 ± 0.432
3.241LeuIle: 3.241 ± 1.056
3.241LeuLys: 3.241 ± 2.34
4.167LeuLeu: 4.167 ± 1.908
2.778LeuMet: 2.778 ± 1.297
0.926LeuAsn: 0.926 ± 0.432
4.167LeuPro: 4.167 ± 0.661
1.389LeuGln: 1.389 ± 0.649
6.481LeuArg: 6.481 ± 0.827
4.63LeuSer: 4.63 ± 0.877
1.389LeuThr: 1.389 ± 0.649
5.556LeuVal: 5.556 ± 0.025
0.463LeuTrp: 0.463 ± 0.216
3.241LeuTyr: 3.241 ± 1.513
0.0LeuXaa: 0.0 ± 0.0
Met
3.704MetAla: 3.704 ± 0.84
1.389MetCys: 1.389 ± 0.649
3.241MetAsp: 3.241 ± 1.513
0.926MetGlu: 0.926 ± 0.432
2.315MetPhe: 2.315 ± 0.204
1.852MetGly: 1.852 ± 0.42
0.926MetHis: 0.926 ± 0.432
0.463MetIle: 0.463 ± 0.216
1.852MetLys: 1.852 ± 0.865
1.852MetLeu: 1.852 ± 0.865
0.463MetMet: 0.463 ± 0.216
0.463MetAsn: 0.463 ± 0.216
0.926MetPro: 0.926 ± 0.432
0.463MetGln: 0.463 ± 0.216
1.852MetArg: 1.852 ± 0.42
1.852MetSer: 1.852 ± 1.704
0.0MetThr: 0.0 ± 0.0
0.463MetVal: 0.463 ± 0.216
0.463MetTrp: 0.463 ± 0.216
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.556AsnAla: 5.556 ± 1.31
0.463AsnCys: 0.463 ± 0.216
1.389AsnAsp: 1.389 ± 0.636
3.704AsnGlu: 3.704 ± 1.729
0.926AsnPhe: 0.926 ± 0.432
0.926AsnGly: 0.926 ± 0.852
1.389AsnHis: 1.389 ± 0.636
3.241AsnIle: 3.241 ± 1.513
3.241AsnLys: 3.241 ± 1.513
3.241AsnLeu: 3.241 ± 2.34
1.852AsnMet: 1.852 ± 0.203
2.315AsnAsn: 2.315 ± 0.204
2.315AsnPro: 2.315 ± 0.204
0.0AsnGln: 0.0 ± 0.0
1.389AsnArg: 1.389 ± 0.649
1.389AsnSer: 1.389 ± 0.649
2.315AsnThr: 2.315 ± 0.204
4.167AsnVal: 4.167 ± 4.477
0.463AsnTrp: 0.463 ± 0.216
3.241AsnTyr: 3.241 ± 0.229
0.0AsnXaa: 0.0 ± 0.0
Pro
2.778ProAla: 2.778 ± 1.272
0.0ProCys: 0.0 ± 0.0
3.704ProAsp: 3.704 ± 1.729
1.852ProGlu: 1.852 ± 0.865
0.926ProPhe: 0.926 ± 0.432
0.926ProGly: 0.926 ± 0.432
0.926ProHis: 0.926 ± 0.432
3.241ProIle: 3.241 ± 2.34
1.389ProLys: 1.389 ± 0.636
2.315ProLeu: 2.315 ± 0.204
0.463ProMet: 0.463 ± 0.216
3.241ProAsn: 3.241 ± 1.513
2.778ProPro: 2.778 ± 1.297
1.389ProGln: 1.389 ± 0.649
3.704ProArg: 3.704 ± 0.84
2.315ProSer: 2.315 ± 1.488
1.852ProThr: 1.852 ± 0.865
4.167ProVal: 4.167 ± 0.661
0.0ProTrp: 0.0 ± 0.0
0.926ProTyr: 0.926 ± 0.432
0.0ProXaa: 0.0 ± 0.0
Gln
1.852GlnAla: 1.852 ± 0.865
0.0GlnCys: 0.0 ± 0.0
0.926GlnAsp: 0.926 ± 0.432
0.0GlnGlu: 0.0 ± 0.0
1.389GlnPhe: 1.389 ± 0.636
1.852GlnGly: 1.852 ± 0.865
0.926GlnHis: 0.926 ± 0.432
3.241GlnIle: 3.241 ± 0.229
2.315GlnLys: 2.315 ± 1.081
0.926GlnLeu: 0.926 ± 0.432
0.463GlnMet: 0.463 ± 0.216
1.389GlnAsn: 1.389 ± 0.636
0.926GlnPro: 0.926 ± 0.432
0.926GlnGln: 0.926 ± 0.852
0.0GlnArg: 0.0 ± 0.0
1.389GlnSer: 1.389 ± 0.636
0.926GlnThr: 0.926 ± 0.852
1.852GlnVal: 1.852 ± 0.865
0.463GlnTrp: 0.463 ± 0.216
1.852GlnTyr: 1.852 ± 0.42
0.0GlnXaa: 0.0 ± 0.0
Arg
6.019ArgAla: 6.019 ± 1.526
0.926ArgCys: 0.926 ± 0.432
4.63ArgAsp: 4.63 ± 1.692
4.167ArgGlu: 4.167 ± 1.946
3.241ArgPhe: 3.241 ± 1.513
2.315ArgGly: 2.315 ± 1.081
2.315ArgHis: 2.315 ± 0.204
0.463ArgIle: 0.463 ± 0.216
5.556ArgLys: 5.556 ± 1.31
3.704ArgLeu: 3.704 ± 0.445
0.926ArgMet: 0.926 ± 0.564
2.778ArgAsn: 2.778 ± 2.557
0.463ArgPro: 0.463 ± 0.216
0.926ArgGln: 0.926 ± 0.432
2.778ArgArg: 2.778 ± 0.012
6.019ArgSer: 6.019 ± 2.81
2.315ArgThr: 2.315 ± 0.204
1.852ArgVal: 1.852 ± 0.865
0.463ArgTrp: 0.463 ± 0.216
3.704ArgTyr: 3.704 ± 0.445
0.0ArgXaa: 0.0 ± 0.0
Ser
7.407SerAla: 7.407 ± 0.89
0.926SerCys: 0.926 ± 0.432
3.241SerAsp: 3.241 ± 2.34
3.704SerGlu: 3.704 ± 0.84
1.852SerPhe: 1.852 ± 0.865
3.704SerGly: 3.704 ± 0.84
1.389SerHis: 1.389 ± 0.636
4.63SerIle: 4.63 ± 0.877
2.315SerLys: 2.315 ± 1.081
4.167SerLeu: 4.167 ± 0.661
1.389SerMet: 1.389 ± 0.649
2.778SerAsn: 2.778 ± 0.012
1.852SerPro: 1.852 ± 0.42
0.463SerGln: 0.463 ± 0.216
2.778SerArg: 2.778 ± 1.297
5.556SerSer: 5.556 ± 1.31
5.556SerThr: 5.556 ± 2.544
7.87SerVal: 7.87 ± 1.106
0.463SerTrp: 0.463 ± 0.216
1.852SerTyr: 1.852 ± 0.42
0.0SerXaa: 0.0 ± 0.0
Thr
3.704ThrAla: 3.704 ± 2.124
1.389ThrCys: 1.389 ± 0.649
3.241ThrAsp: 3.241 ± 1.513
0.926ThrGlu: 0.926 ± 0.432
4.63ThrPhe: 4.63 ± 1.692
4.167ThrGly: 4.167 ± 3.193
1.389ThrHis: 1.389 ± 1.921
6.481ThrIle: 6.481 ± 0.827
4.63ThrLys: 4.63 ± 1.692
4.167ThrLeu: 4.167 ± 0.661
0.926ThrMet: 0.926 ± 0.432
3.241ThrAsn: 3.241 ± 2.34
2.315ThrPro: 2.315 ± 1.081
0.463ThrGln: 0.463 ± 0.216
2.778ThrArg: 2.778 ± 1.297
5.093ThrSer: 5.093 ± 2.378
2.315ThrThr: 2.315 ± 0.204
4.167ThrVal: 4.167 ± 1.908
0.926ThrTrp: 0.926 ± 0.432
1.852ThrTyr: 1.852 ± 0.865
0.0ThrXaa: 0.0 ± 0.0
Val
6.481ValAla: 6.481 ± 0.827
0.926ValCys: 0.926 ± 0.432
5.556ValAsp: 5.556 ± 5.113
1.852ValGlu: 1.852 ± 0.865
4.167ValPhe: 4.167 ± 1.908
4.63ValGly: 4.63 ± 4.261
1.389ValHis: 1.389 ± 0.649
2.315ValIle: 2.315 ± 0.204
6.481ValLys: 6.481 ± 0.457
7.407ValLeu: 7.407 ± 0.89
1.389ValMet: 1.389 ± 0.649
5.556ValAsn: 5.556 ± 1.26
1.389ValPro: 1.389 ± 0.649
0.926ValGln: 0.926 ± 0.432
2.778ValArg: 2.778 ± 0.012
4.167ValSer: 4.167 ± 0.624
6.019ValThr: 6.019 ± 1.043
5.093ValVal: 5.093 ± 1.476
0.463ValTrp: 0.463 ± 0.216
4.167ValTyr: 4.167 ± 0.661
0.0ValXaa: 0.0 ± 0.0
Trp
1.389TrpAla: 1.389 ± 0.636
0.463TrpCys: 0.463 ± 0.216
0.463TrpAsp: 0.463 ± 0.216
0.0TrpGlu: 0.0 ± 0.0
0.926TrpPhe: 0.926 ± 0.432
0.463TrpGly: 0.463 ± 0.216
0.463TrpHis: 0.463 ± 0.216
0.463TrpIle: 0.463 ± 0.216
0.0TrpLys: 0.0 ± 0.0
0.926TrpLeu: 0.926 ± 0.432
0.0TrpMet: 0.0 ± 0.0
0.463TrpAsn: 0.463 ± 0.216
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.926TrpArg: 0.926 ± 0.432
1.852TrpSer: 1.852 ± 0.865
0.0TrpThr: 0.0 ± 0.0
0.463TrpVal: 0.463 ± 0.216
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.704TyrAla: 3.704 ± 1.729
1.389TyrCys: 1.389 ± 0.649
3.704TyrAsp: 3.704 ± 2.124
2.315TyrGlu: 2.315 ± 1.081
0.926TyrPhe: 0.926 ± 0.432
0.926TyrGly: 0.926 ± 0.432
1.852TyrHis: 1.852 ± 0.865
1.852TyrIle: 1.852 ± 0.865
2.778TyrLys: 2.778 ± 0.012
1.389TyrLeu: 1.389 ± 0.649
1.389TyrMet: 1.389 ± 0.649
2.778TyrAsn: 2.778 ± 1.297
1.389TyrPro: 1.389 ± 1.921
0.926TyrGln: 0.926 ± 0.432
3.241TyrArg: 3.241 ± 0.229
1.852TyrSer: 1.852 ± 0.865
3.241TyrThr: 3.241 ± 0.229
3.241TyrVal: 3.241 ± 0.229
0.926TyrTrp: 0.926 ± 0.432
0.926TyrTyr: 0.926 ± 0.432
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2161 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski