Amino acid dipepetide frequency for Torque teno virus 16

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.55AlaAla: 6.55 ± 2.866
0.0AlaCys: 0.0 ± 0.0
1.092AlaAsp: 1.092 ± 0.496
1.092AlaGlu: 1.092 ± 0.496
2.183AlaPhe: 2.183 ± 0.991
4.367AlaGly: 4.367 ± 6.777
0.0AlaHis: 0.0 ± 0.0
3.275AlaIle: 3.275 ± 1.487
1.092AlaLys: 1.092 ± 2.424
5.459AlaLeu: 5.459 ± 6.281
1.092AlaMet: 1.092 ± 2.424
1.092AlaAsn: 1.092 ± 2.424
4.367AlaPro: 4.367 ± 9.696
2.183AlaGln: 2.183 ± 0.991
1.092AlaArg: 1.092 ± 0.496
0.0AlaSer: 0.0 ± 0.0
5.459AlaThr: 5.459 ± 6.281
3.275AlaVal: 3.275 ± 4.353
1.092AlaTrp: 1.092 ± 2.424
4.367AlaTyr: 4.367 ± 1.983
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.092CysAsp: 1.092 ± 0.496
0.0CysGlu: 0.0 ± 0.0
1.092CysPhe: 1.092 ± 0.496
5.459CysGly: 5.459 ± 3.361
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.183CysLys: 2.183 ± 0.991
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.183CysAsn: 2.183 ± 0.991
1.092CysPro: 1.092 ± 0.496
0.0CysGln: 0.0 ± 0.0
1.092CysArg: 1.092 ± 0.496
1.092CysSer: 1.092 ± 0.496
2.183CysThr: 2.183 ± 0.991
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.092CysTyr: 1.092 ± 0.496
0.0CysXaa: 0.0 ± 0.0
Asp
1.092AspAla: 1.092 ± 2.424
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
3.275AspGlu: 3.275 ± 1.433
2.183AspPhe: 2.183 ± 0.991
1.092AspGly: 1.092 ± 0.496
1.092AspHis: 1.092 ± 0.496
1.092AspIle: 1.092 ± 0.496
3.275AspLys: 3.275 ± 1.487
3.275AspLeu: 3.275 ± 1.487
2.183AspMet: 2.183 ± 0.991
1.092AspAsn: 1.092 ± 0.496
2.183AspPro: 2.183 ± 4.848
3.275AspGln: 3.275 ± 1.487
0.0AspArg: 0.0 ± 0.0
5.459AspSer: 5.459 ± 2.478
2.183AspThr: 2.183 ± 0.991
0.0AspVal: 0.0 ± 0.0
0.0AspTrp: 0.0 ± 0.0
6.55AspTyr: 6.55 ± 0.054
0.0AspXaa: 0.0 ± 0.0
Glu
1.092GluAla: 1.092 ± 0.496
0.0GluCys: 0.0 ± 0.0
5.459GluAsp: 5.459 ± 0.441
5.459GluGlu: 5.459 ± 6.281
1.092GluPhe: 1.092 ± 0.496
4.367GluGly: 4.367 ± 6.777
0.0GluHis: 0.0 ± 0.0
1.092GluIle: 1.092 ± 0.496
3.275GluLys: 3.275 ± 1.487
3.275GluLeu: 3.275 ± 7.272
1.092GluMet: 1.092 ± 0.496
1.092GluAsn: 1.092 ± 0.496
1.092GluPro: 1.092 ± 0.496
2.183GluGln: 2.183 ± 1.928
1.092GluArg: 1.092 ± 0.496
3.275GluSer: 3.275 ± 1.433
2.183GluThr: 2.183 ± 0.991
4.367GluVal: 4.367 ± 1.983
0.0GluTrp: 0.0 ± 0.0
2.183GluTyr: 2.183 ± 0.991
0.0GluXaa: 0.0 ± 0.0
Phe
2.183PheAla: 2.183 ± 1.928
2.183PheCys: 2.183 ± 1.928
2.183PheAsp: 2.183 ± 0.991
3.275PheGlu: 3.275 ± 1.433
1.092PhePhe: 1.092 ± 0.496
4.367PheGly: 4.367 ± 1.983
1.092PheHis: 1.092 ± 0.496
3.275PheIle: 3.275 ± 1.487
1.092PheLys: 1.092 ± 0.496
2.183PheLeu: 2.183 ± 0.991
0.0PheMet: 0.0 ± 0.0
5.459PheAsn: 5.459 ± 0.441
2.183PhePro: 2.183 ± 0.991
5.459PheGln: 5.459 ± 2.478
2.183PheArg: 2.183 ± 1.928
4.367PheSer: 4.367 ± 1.983
5.459PheThr: 5.459 ± 3.361
1.092PheVal: 1.092 ± 0.496
0.0PheTrp: 0.0 ± 0.0
1.092PheTyr: 1.092 ± 0.496
0.0PheXaa: 0.0 ± 0.0
Gly
3.275GlyAla: 3.275 ± 7.272
2.183GlyCys: 2.183 ± 1.928
4.367GlyAsp: 4.367 ± 3.857
3.275GlyGlu: 3.275 ± 1.433
2.183GlyPhe: 2.183 ± 0.991
9.825GlyGly: 9.825 ± 7.218
0.0GlyHis: 0.0 ± 0.0
2.183GlyIle: 2.183 ± 1.928
3.275GlyLys: 3.275 ± 1.487
4.367GlyLeu: 4.367 ± 1.983
1.092GlyMet: 1.092 ± 0.825
3.275GlyAsn: 3.275 ± 1.487
5.459GlyPro: 5.459 ± 0.441
1.092GlyGln: 1.092 ± 0.496
7.642GlyArg: 7.642 ± 2.37
3.275GlySer: 3.275 ± 1.433
4.367GlyThr: 4.367 ± 1.983
0.0GlyVal: 0.0 ± 0.0
3.275GlyTrp: 3.275 ± 1.487
3.275GlyTyr: 3.275 ± 1.487
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.092HisCys: 1.092 ± 0.496
0.0HisAsp: 0.0 ± 0.0
1.092HisGlu: 1.092 ± 0.496
2.183HisPhe: 2.183 ± 4.848
0.0HisGly: 0.0 ± 0.0
1.092HisHis: 1.092 ± 2.424
0.0HisIle: 0.0 ± 0.0
1.092HisLys: 1.092 ± 0.496
1.092HisLeu: 1.092 ± 0.496
1.092HisMet: 1.092 ± 0.496
0.0HisAsn: 0.0 ± 0.0
1.092HisPro: 1.092 ± 0.496
1.092HisGln: 1.092 ± 0.496
0.0HisArg: 0.0 ± 0.0
1.092HisSer: 1.092 ± 2.424
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
3.275HisTyr: 3.275 ± 1.487
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
3.275IleCys: 3.275 ± 1.487
0.0IleAsp: 0.0 ± 0.0
0.0IleGlu: 0.0 ± 0.0
3.275IlePhe: 3.275 ± 1.487
2.183IleGly: 2.183 ± 0.991
0.0IleHis: 0.0 ± 0.0
5.459IleIle: 5.459 ± 2.478
2.183IleLys: 2.183 ± 0.991
3.275IleLeu: 3.275 ± 1.487
1.092IleMet: 1.092 ± 0.496
1.092IleAsn: 1.092 ± 2.424
4.367IlePro: 4.367 ± 1.983
1.092IleGln: 1.092 ± 0.496
3.275IleArg: 3.275 ± 1.433
1.092IleSer: 1.092 ± 0.496
1.092IleThr: 1.092 ± 0.496
3.275IleVal: 3.275 ± 1.487
1.092IleTrp: 1.092 ± 0.496
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.275LysAla: 3.275 ± 1.433
0.0LysCys: 0.0 ± 0.0
2.183LysAsp: 2.183 ± 0.991
1.092LysGlu: 1.092 ± 0.496
0.0LysPhe: 0.0 ± 0.0
4.367LysGly: 4.367 ± 1.983
2.183LysHis: 2.183 ± 0.991
4.367LysIle: 4.367 ± 1.983
5.459LysLys: 5.459 ± 2.478
5.459LysLeu: 5.459 ± 0.441
2.183LysMet: 2.183 ± 0.991
6.55LysAsn: 6.55 ± 2.974
2.183LysPro: 2.183 ± 0.991
3.275LysGln: 3.275 ± 1.487
4.367LysArg: 4.367 ± 0.937
1.092LysSer: 1.092 ± 0.496
3.275LysThr: 3.275 ± 1.487
2.183LysVal: 2.183 ± 0.991
1.092LysTrp: 1.092 ± 0.496
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.367LeuAla: 4.367 ± 3.857
1.092LeuCys: 1.092 ± 0.496
3.275LeuAsp: 3.275 ± 4.353
4.367LeuGlu: 4.367 ± 0.937
2.183LeuPhe: 2.183 ± 1.928
3.275LeuGly: 3.275 ± 1.487
2.183LeuHis: 2.183 ± 1.928
3.275LeuIle: 3.275 ± 1.487
5.459LeuLys: 5.459 ± 2.478
6.55LeuLeu: 6.55 ± 2.866
2.183LeuMet: 2.183 ± 0.991
3.275LeuAsn: 3.275 ± 1.487
5.459LeuPro: 5.459 ± 6.281
9.825LeuGln: 9.825 ± 1.541
5.459LeuArg: 5.459 ± 3.361
5.459LeuSer: 5.459 ± 2.478
2.183LeuThr: 2.183 ± 0.991
1.092LeuVal: 1.092 ± 0.496
2.183LeuTrp: 2.183 ± 0.991
3.275LeuTyr: 3.275 ± 1.487
0.0LeuXaa: 0.0 ± 0.0
Met
1.092MetAla: 1.092 ± 0.496
0.0MetCys: 0.0 ± 0.0
1.092MetAsp: 1.092 ± 0.496
1.092MetGlu: 1.092 ± 0.496
0.0MetPhe: 0.0 ± 0.0
1.092MetGly: 1.092 ± 0.496
1.092MetHis: 1.092 ± 2.424
1.092MetIle: 1.092 ± 0.496
0.0MetLys: 0.0 ± 0.0
2.183MetLeu: 2.183 ± 0.991
0.0MetMet: 0.0 ± 0.0
1.092MetAsn: 1.092 ± 0.496
2.183MetPro: 2.183 ± 0.991
1.092MetGln: 1.092 ± 0.496
0.0MetArg: 0.0 ± 0.0
2.183MetSer: 2.183 ± 1.928
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.275MetTyr: 3.275 ± 1.487
0.0MetXaa: 0.0 ± 0.0
Asn
1.092AsnAla: 1.092 ± 2.424
0.0AsnCys: 0.0 ± 0.0
2.183AsnAsp: 2.183 ± 0.991
1.092AsnGlu: 1.092 ± 0.496
4.367AsnPhe: 4.367 ± 1.983
1.092AsnGly: 1.092 ± 0.496
0.0AsnHis: 0.0 ± 0.0
3.275AsnIle: 3.275 ± 1.487
1.092AsnLys: 1.092 ± 0.496
4.367AsnLeu: 4.367 ± 0.937
0.0AsnMet: 0.0 ± 0.0
2.183AsnAsn: 2.183 ± 0.991
8.734AsnPro: 8.734 ± 3.965
2.183AsnGln: 2.183 ± 1.928
3.275AsnArg: 3.275 ± 1.487
2.183AsnSer: 2.183 ± 0.991
3.275AsnThr: 3.275 ± 1.487
2.183AsnVal: 2.183 ± 0.991
4.367AsnTrp: 4.367 ± 1.983
4.367AsnTyr: 4.367 ± 0.937
0.0AsnXaa: 0.0 ± 0.0
Pro
9.825ProAla: 9.825 ± 13.058
2.183ProCys: 2.183 ± 0.991
1.092ProAsp: 1.092 ± 0.496
0.0ProGlu: 0.0 ± 0.0
3.275ProPhe: 3.275 ± 1.487
4.367ProGly: 4.367 ± 0.937
0.0ProHis: 0.0 ± 0.0
1.092ProIle: 1.092 ± 0.496
4.367ProLys: 4.367 ± 0.937
7.642ProLeu: 7.642 ± 0.55
2.183ProMet: 2.183 ± 0.991
4.367ProAsn: 4.367 ± 1.983
5.459ProPro: 5.459 ± 3.361
6.55ProGln: 6.55 ± 2.974
5.459ProArg: 5.459 ± 0.441
6.55ProSer: 6.55 ± 2.866
5.459ProThr: 5.459 ± 3.361
4.367ProVal: 4.367 ± 0.937
1.092ProTrp: 1.092 ± 0.496
3.275ProTyr: 3.275 ± 1.487
0.0ProXaa: 0.0 ± 0.0
Gln
1.092GlnAla: 1.092 ± 2.424
3.275GlnCys: 3.275 ± 1.487
3.275GlnAsp: 3.275 ± 1.487
4.367GlnGlu: 4.367 ± 1.983
4.367GlnPhe: 4.367 ± 1.983
1.092GlnGly: 1.092 ± 2.424
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.092GlnLys: 1.092 ± 0.496
10.917GlnLeu: 10.917 ± 4.957
0.0GlnMet: 0.0 ± 0.0
1.092GlnAsn: 1.092 ± 0.496
3.275GlnPro: 3.275 ± 1.487
10.917GlnGln: 10.917 ± 2.037
1.092GlnArg: 1.092 ± 0.496
2.183GlnSer: 2.183 ± 0.991
6.55GlnThr: 6.55 ± 2.974
5.459GlnVal: 5.459 ± 2.478
2.183GlnTrp: 2.183 ± 1.928
2.183GlnTyr: 2.183 ± 0.991
0.0GlnXaa: 0.0 ± 0.0
Arg
5.459ArgAla: 5.459 ± 3.361
1.092ArgCys: 1.092 ± 0.496
1.092ArgAsp: 1.092 ± 0.496
4.367ArgGlu: 4.367 ± 6.777
4.367ArgPhe: 4.367 ± 0.937
7.642ArgGly: 7.642 ± 2.37
0.0ArgHis: 0.0 ± 0.0
1.092ArgIle: 1.092 ± 0.496
4.367ArgLys: 4.367 ± 0.937
3.275ArgLeu: 3.275 ± 1.433
1.092ArgMet: 1.092 ± 0.496
1.092ArgAsn: 1.092 ± 0.496
6.55ArgPro: 6.55 ± 0.054
1.092ArgGln: 1.092 ± 0.496
33.843ArgArg: 33.843 ± 9.526
2.183ArgSer: 2.183 ± 1.928
3.275ArgThr: 3.275 ± 1.487
2.183ArgVal: 2.183 ± 1.928
5.459ArgTrp: 5.459 ± 2.478
4.367ArgTyr: 4.367 ± 1.983
0.0ArgXaa: 0.0 ± 0.0
Ser
1.092SerAla: 1.092 ± 2.424
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
3.275SerGlu: 3.275 ± 1.433
4.367SerPhe: 4.367 ± 3.857
6.55SerGly: 6.55 ± 2.974
2.183SerHis: 2.183 ± 1.928
1.092SerIle: 1.092 ± 0.496
5.459SerLys: 5.459 ± 2.478
1.092SerLeu: 1.092 ± 0.496
2.183SerMet: 2.183 ± 0.849
4.367SerAsn: 4.367 ± 1.983
8.734SerPro: 8.734 ± 1.046
0.0SerGln: 0.0 ± 0.0
2.183SerArg: 2.183 ± 1.928
1.092SerSer: 1.092 ± 2.424
6.55SerThr: 6.55 ± 0.054
1.092SerVal: 1.092 ± 0.496
1.092SerTrp: 1.092 ± 0.496
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.459ThrAla: 5.459 ± 2.478
0.0ThrCys: 0.0 ± 0.0
3.275ThrAsp: 3.275 ± 1.487
1.092ThrGlu: 1.092 ± 0.496
5.459ThrPhe: 5.459 ± 2.478
3.275ThrGly: 3.275 ± 1.433
1.092ThrHis: 1.092 ± 0.496
1.092ThrIle: 1.092 ± 2.424
2.183ThrLys: 2.183 ± 0.991
3.275ThrLeu: 3.275 ± 1.433
0.0ThrMet: 0.0 ± 0.0
3.275ThrAsn: 3.275 ± 1.433
5.459ThrPro: 5.459 ± 3.361
6.55ThrGln: 6.55 ± 2.974
5.459ThrArg: 5.459 ± 0.441
5.459ThrSer: 5.459 ± 0.441
6.55ThrThr: 6.55 ± 0.054
4.367ThrVal: 4.367 ± 1.983
0.0ThrTrp: 0.0 ± 0.0
4.367ThrTyr: 4.367 ± 1.983
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
1.092ValCys: 1.092 ± 0.496
3.275ValAsp: 3.275 ± 1.487
3.275ValGlu: 3.275 ± 1.433
0.0ValPhe: 0.0 ± 0.0
0.0ValGly: 0.0 ± 0.0
1.092ValHis: 1.092 ± 0.496
1.092ValIle: 1.092 ± 0.496
4.367ValLys: 4.367 ± 1.983
4.367ValLeu: 4.367 ± 0.937
0.0ValMet: 0.0 ± 0.0
1.092ValAsn: 1.092 ± 0.496
3.275ValPro: 3.275 ± 1.487
3.275ValGln: 3.275 ± 1.487
4.367ValArg: 4.367 ± 3.857
3.275ValSer: 3.275 ± 1.487
1.092ValThr: 1.092 ± 0.496
3.275ValVal: 3.275 ± 1.487
1.092ValTrp: 1.092 ± 0.496
2.183ValTyr: 2.183 ± 0.991
0.0ValXaa: 0.0 ± 0.0
Trp
1.092TrpAla: 1.092 ± 0.496
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
5.459TrpPhe: 5.459 ± 0.441
3.275TrpGly: 3.275 ± 1.487
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.092TrpLeu: 1.092 ± 0.496
0.0TrpMet: 0.0 ± 0.0
1.092TrpAsn: 1.092 ± 0.496
2.183TrpPro: 2.183 ± 1.928
2.183TrpGln: 2.183 ± 0.991
5.459TrpArg: 5.459 ± 2.478
1.092TrpSer: 1.092 ± 0.496
2.183TrpThr: 2.183 ± 0.991
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.092TrpTyr: 1.092 ± 0.496
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.092TyrAla: 1.092 ± 0.496
1.092TyrCys: 1.092 ± 0.496
4.367TyrAsp: 4.367 ± 1.983
2.183TyrGlu: 2.183 ± 0.991
1.092TyrPhe: 1.092 ± 0.496
1.092TyrGly: 1.092 ± 0.496
2.183TyrHis: 2.183 ± 0.991
3.275TyrIle: 3.275 ± 1.487
3.275TyrLys: 3.275 ± 1.487
3.275TyrLeu: 3.275 ± 1.433
0.0TyrMet: 0.0 ± 0.0
6.55TyrAsn: 6.55 ± 2.974
3.275TyrPro: 3.275 ± 1.487
1.092TyrGln: 1.092 ± 0.496
6.55TyrArg: 6.55 ± 0.054
0.0TyrSer: 0.0 ± 0.0
4.367TyrThr: 4.367 ± 1.983
3.275TyrVal: 3.275 ± 1.487
2.183TyrTrp: 2.183 ± 0.991
3.275TyrTyr: 3.275 ± 1.487
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (917 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski