Amino acid dipepetide frequency for Chryseobacterium taihuense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.19AlaAla: 4.19 ± 0.084	0.479AlaCys: 0.479 ± 0.021	3.431AlaAsp: 3.431 ± 0.063	4.31AlaGlu: 4.31 ± 0.078	3.123AlaPhe: 3.123 ± 0.058	4.344AlaGly: 4.344 ± 0.097	0.947AlaHis: 0.947 ± 0.034	4.457AlaIle: 4.457 ± 0.078	4.897AlaLys: 4.897 ± 0.081	5.435AlaLeu: 5.435 ± 0.081	1.448AlaMet: 1.448 ± 0.038	3.431AlaAsn: 3.431 ± 0.075	1.75AlaPro: 1.75 ± 0.047	2.458AlaGln: 2.458 ± 0.044	1.84AlaArg: 1.84 ± 0.049	3.729AlaSer: 3.729 ± 0.078	3.291AlaThr: 3.291 ± 0.08	4.29AlaVal: 4.29 ± 0.07	0.545AlaTrp: 0.545 ± 0.026	2.192AlaTyr: 2.192 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.424CysAla: 0.424 ± 0.021	0.114CysCys: 0.114 ± 0.012	0.406CysAsp: 0.406 ± 0.023	0.455CysGlu: 0.455 ± 0.022	0.478CysPhe: 0.478 ± 0.022	0.621CysGly: 0.621 ± 0.024	0.172CysHis: 0.172 ± 0.012	0.635CysIle: 0.635 ± 0.027	0.502CysLys: 0.502 ± 0.026	0.636CysLeu: 0.636 ± 0.025	0.147CysMet: 0.147 ± 0.013	0.429CysAsn: 0.429 ± 0.019	0.365CysPro: 0.365 ± 0.025	0.21CysGln: 0.21 ± 0.014	0.241CysArg: 0.241 ± 0.015	0.568CysSer: 0.568 ± 0.025	0.423CysThr: 0.423 ± 0.024	0.441CysVal: 0.441 ± 0.021	0.057CysTrp: 0.057 ± 0.007	0.288CysTyr: 0.288 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.224AspAla: 3.224 ± 0.059	0.394AspCys: 0.394 ± 0.022	2.788AspAsp: 2.788 ± 0.058	4.194AspGlu: 4.194 ± 0.072	4.021AspPhe: 4.021 ± 0.071	3.305AspGly: 3.305 ± 0.059	0.924AspHis: 0.924 ± 0.029	4.195AspIle: 4.195 ± 0.061	4.283AspLys: 4.283 ± 0.075	5.071AspLeu: 5.071 ± 0.076	1.051AspMet: 1.051 ± 0.032	2.899AspAsn: 2.899 ± 0.06	1.698AspPro: 1.698 ± 0.044	1.707AspGln: 1.707 ± 0.042	1.816AspArg: 1.816 ± 0.04	3.065AspSer: 3.065 ± 0.063	2.263AspThr: 2.263 ± 0.049	3.236AspVal: 3.236 ± 0.054	0.687AspTrp: 0.687 ± 0.022	2.727AspTyr: 2.727 ± 0.056	0.0AspXaa: 0.0 ± 0.0
Glu	3.864GluAla: 3.864 ± 0.078	0.379GluCys: 0.379 ± 0.019	3.524GluAsp: 3.524 ± 0.069	4.933GluGlu: 4.933 ± 0.094	3.272GluPhe: 3.272 ± 0.058	3.379GluGly: 3.379 ± 0.065	0.979GluHis: 0.979 ± 0.032	6.357GluIle: 6.357 ± 0.097	7.347GluLys: 7.347 ± 0.115	5.646GluLeu: 5.646 ± 0.093	1.756GluMet: 1.756 ± 0.047	5.755GluAsn: 5.755 ± 0.08	1.408GluPro: 1.408 ± 0.038	2.156GluGln: 2.156 ± 0.045	2.412GluArg: 2.412 ± 0.054	3.451GluSer: 3.451 ± 0.061	3.5GluThr: 3.5 ± 0.059	3.987GluVal: 3.987 ± 0.063	0.711GluTrp: 0.711 ± 0.027	2.484GluTyr: 2.484 ± 0.054	0.0GluXaa: 0.0 ± 0.0
Phe	3.308PheAla: 3.308 ± 0.073	0.496PheCys: 0.496 ± 0.023	3.198PheAsp: 3.198 ± 0.059	3.386PheGlu: 3.386 ± 0.059	3.094PhePhe: 3.094 ± 0.069	3.762PheGly: 3.762 ± 0.078	0.909PheHis: 0.909 ± 0.033	4.208PheIle: 4.208 ± 0.069	3.784PheLys: 3.784 ± 0.082	5.194PheLeu: 5.194 ± 0.085	1.14PheMet: 1.14 ± 0.032	3.281PheAsn: 3.281 ± 0.067	1.977PhePro: 1.977 ± 0.048	1.697PheGln: 1.697 ± 0.04	2.005PheArg: 2.005 ± 0.051	4.407PheSer: 4.407 ± 0.067	3.276PheThr: 3.276 ± 0.059	3.245PheVal: 3.245 ± 0.055	0.671PheTrp: 0.671 ± 0.03	2.467PheTyr: 2.467 ± 0.056	0.0PheXaa: 0.0 ± 0.0
Gly	3.837GlyAla: 3.837 ± 0.086	0.546GlyCys: 0.546 ± 0.025	2.906GlyAsp: 2.906 ± 0.057	3.514GlyGlu: 3.514 ± 0.065	3.677GlyPhe: 3.677 ± 0.073	4.277GlyGly: 4.277 ± 0.103	0.914GlyHis: 0.914 ± 0.034	5.516GlyIle: 5.516 ± 0.077	5.422GlyLys: 5.422 ± 0.084	5.286GlyLeu: 5.286 ± 0.084	1.594GlyMet: 1.594 ± 0.046	4.294GlyAsn: 4.294 ± 0.089	1.117GlyPro: 1.117 ± 0.034	1.84GlyGln: 1.84 ± 0.048	2.092GlyArg: 2.092 ± 0.051	3.988GlySer: 3.988 ± 0.084	3.998GlyThr: 3.998 ± 0.11	3.755GlyVal: 3.755 ± 0.075	0.75GlyTrp: 0.75 ± 0.028	2.664GlyTyr: 2.664 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	0.833HisAla: 0.833 ± 0.031	0.167HisCys: 0.167 ± 0.013	0.81HisAsp: 0.81 ± 0.03	0.937HisGlu: 0.937 ± 0.036	1.096HisPhe: 1.096 ± 0.036	0.951HisGly: 0.951 ± 0.035	0.486HisHis: 0.486 ± 0.026	1.313HisIle: 1.313 ± 0.039	1.131HisLys: 1.131 ± 0.035	1.703HisLeu: 1.703 ± 0.045	0.279HisMet: 0.279 ± 0.018	0.869HisAsn: 0.869 ± 0.032	0.845HisPro: 0.845 ± 0.032	0.777HisGln: 0.777 ± 0.032	0.623HisArg: 0.623 ± 0.027	1.086HisSer: 1.086 ± 0.032	0.803HisThr: 0.803 ± 0.031	0.656HisVal: 0.656 ± 0.025	0.217HisTrp: 0.217 ± 0.014	0.815HisTyr: 0.815 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.152IleAla: 5.152 ± 0.073	0.715IleCys: 0.715 ± 0.028	4.537IleAsp: 4.537 ± 0.077	5.221IleGlu: 5.221 ± 0.091	4.425IlePhe: 4.425 ± 0.085	4.805IleGly: 4.805 ± 0.078	1.317IleHis: 1.317 ± 0.036	6.526IleIle: 6.526 ± 0.102	6.153IleLys: 6.153 ± 0.088	7.643IleLeu: 7.643 ± 0.095	1.472IleMet: 1.472 ± 0.036	5.144IleAsn: 5.144 ± 0.082	3.392IlePro: 3.392 ± 0.062	2.784IleGln: 2.784 ± 0.056	2.594IleArg: 2.594 ± 0.051	6.367IleSer: 6.367 ± 0.086	4.524IleThr: 4.524 ± 0.08	4.588IleVal: 4.588 ± 0.07	0.68IleTrp: 0.68 ± 0.026	3.052IleTyr: 3.052 ± 0.069	0.0IleXaa: 0.0 ± 0.0
Lys	4.877LysAla: 4.877 ± 0.075	0.4LysCys: 0.4 ± 0.022	4.881LysAsp: 4.881 ± 0.09	6.302LysGlu: 6.302 ± 0.104	3.651LysPhe: 3.651 ± 0.064	4.342LysGly: 4.342 ± 0.07	1.27LysHis: 1.27 ± 0.041	7.836LysIle: 7.836 ± 0.105	7.837LysLys: 7.837 ± 0.118	6.682LysLeu: 6.682 ± 0.086	2.413LysMet: 2.413 ± 0.044	6.751LysAsn: 6.751 ± 0.099	2.571LysPro: 2.571 ± 0.059	2.641LysGln: 2.641 ± 0.056	2.61LysArg: 2.61 ± 0.057	4.98LysSer: 4.98 ± 0.072	4.826LysThr: 4.826 ± 0.076	4.734LysVal: 4.734 ± 0.077	0.73LysTrp: 0.73 ± 0.026	3.33LysTyr: 3.33 ± 0.062	0.0LysXaa: 0.0 ± 0.0
Leu	5.411LeuAla: 5.411 ± 0.072	0.67LeuCys: 0.67 ± 0.026	4.667LeuAsp: 4.667 ± 0.073	5.798LeuGlu: 5.798 ± 0.098	4.72LeuPhe: 4.72 ± 0.079	5.623LeuGly: 5.623 ± 0.084	1.482LeuHis: 1.482 ± 0.041	6.754LeuIle: 6.754 ± 0.091	8.123LeuLys: 8.123 ± 0.109	7.884LeuLeu: 7.884 ± 0.111	2.295LeuMet: 2.295 ± 0.046	5.811LeuAsn: 5.811 ± 0.079	3.474LeuPro: 3.474 ± 0.065	3.314LeuGln: 3.314 ± 0.06	2.952LeuArg: 2.952 ± 0.059	6.594LeuSer: 6.594 ± 0.086	4.746LeuThr: 4.746 ± 0.076	4.752LeuVal: 4.752 ± 0.07	0.782LeuTrp: 0.782 ± 0.028	3.184LeuTyr: 3.184 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	1.472MetAla: 1.472 ± 0.037	0.131MetCys: 0.131 ± 0.011	1.086MetAsp: 1.086 ± 0.035	1.527MetGlu: 1.527 ± 0.043	0.971MetPhe: 0.971 ± 0.034	1.342MetGly: 1.342 ± 0.041	0.368MetHis: 0.368 ± 0.022	1.859MetIle: 1.859 ± 0.048	2.627MetLys: 2.627 ± 0.057	1.906MetLeu: 1.906 ± 0.041	0.813MetMet: 0.813 ± 0.032	1.646MetAsn: 1.646 ± 0.041	0.808MetPro: 0.808 ± 0.031	0.82MetGln: 0.82 ± 0.028	0.826MetArg: 0.826 ± 0.031	1.459MetSer: 1.459 ± 0.036	1.19MetThr: 1.19 ± 0.032	1.327MetVal: 1.327 ± 0.04	0.178MetTrp: 0.178 ± 0.013	0.755MetTyr: 0.755 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.87AsnAla: 3.87 ± 0.072	0.517AsnCys: 0.517 ± 0.024	3.292AsnAsp: 3.292 ± 0.062	4.017AsnGlu: 4.017 ± 0.066	3.763AsnPhe: 3.763 ± 0.072	4.254AsnGly: 4.254 ± 0.092	1.155AsnHis: 1.155 ± 0.04	5.748AsnIle: 5.748 ± 0.077	4.518AsnLys: 4.518 ± 0.08	6.071AsnLeu: 6.071 ± 0.081	1.332AsnMet: 1.332 ± 0.037	4.341AsnAsn: 4.341 ± 0.102	3.048AsnPro: 3.048 ± 0.067	2.444AsnGln: 2.444 ± 0.051	2.164AsnArg: 2.164 ± 0.055	4.449AsnSer: 4.449 ± 0.092	3.563AsnThr: 3.563 ± 0.085	3.649AsnVal: 3.649 ± 0.072	0.767AsnTrp: 0.767 ± 0.031	3.131AsnTyr: 3.131 ± 0.066	0.0AsnXaa: 0.0 ± 0.0
Pro	2.136ProAla: 2.136 ± 0.049	0.228ProCys: 0.228 ± 0.016	1.967ProAsp: 1.967 ± 0.05	2.948ProGlu: 2.948 ± 0.066	1.875ProPhe: 1.875 ± 0.049	1.871ProGly: 1.871 ± 0.051	0.56ProHis: 0.56 ± 0.024	2.28ProIle: 2.28 ± 0.048	2.663ProLys: 2.663 ± 0.052	2.668ProLeu: 2.668 ± 0.051	0.733ProMet: 0.733 ± 0.025	2.254ProAsn: 2.254 ± 0.054	0.823ProPro: 0.823 ± 0.038	1.309ProGln: 1.309 ± 0.04	0.888ProArg: 0.888 ± 0.031	2.16ProSer: 2.16 ± 0.051	2.005ProThr: 2.005 ± 0.059	2.661ProVal: 2.661 ± 0.056	0.302ProTrp: 0.302 ± 0.015	1.35ProTyr: 1.35 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	1.785GlnAla: 1.785 ± 0.05	0.174GlnCys: 0.174 ± 0.012	1.658GlnAsp: 1.658 ± 0.039	2.335GlnGlu: 2.335 ± 0.051	1.832GlnPhe: 1.832 ± 0.038	1.731GlnGly: 1.731 ± 0.048	0.568GlnHis: 0.568 ± 0.029	2.956GlnIle: 2.956 ± 0.07	3.524GlnLys: 3.524 ± 0.067	3.249GlnLeu: 3.249 ± 0.058	0.892GlnMet: 0.892 ± 0.028	2.918GlnAsn: 2.918 ± 0.064	1.128GlnPro: 1.128 ± 0.034	1.615GlnGln: 1.615 ± 0.05	1.244GlnArg: 1.244 ± 0.04	2.091GlnSer: 2.091 ± 0.051	1.944GlnThr: 1.944 ± 0.049	1.793GlnVal: 1.793 ± 0.049	0.374GlnTrp: 0.374 ± 0.022	1.555GlnTyr: 1.555 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	1.748ArgAla: 1.748 ± 0.044	0.19ArgCys: 0.19 ± 0.015	1.627ArgAsp: 1.627 ± 0.042	2.248ArgGlu: 2.248 ± 0.052	1.931ArgPhe: 1.931 ± 0.044	1.738ArgGly: 1.738 ± 0.041	0.569ArgHis: 0.569 ± 0.025	2.88ArgIle: 2.88 ± 0.052	3.265ArgLys: 3.265 ± 0.055	2.957ArgLeu: 2.957 ± 0.063	0.954ArgMet: 0.954 ± 0.03	2.472ArgAsn: 2.472 ± 0.066	1.028ArgPro: 1.028 ± 0.031	1.147ArgGln: 1.147 ± 0.04	1.275ArgArg: 1.275 ± 0.036	1.837ArgSer: 1.837 ± 0.051	1.71ArgThr: 1.71 ± 0.045	1.83ArgVal: 1.83 ± 0.04	0.335ArgTrp: 0.335 ± 0.018	1.359ArgTyr: 1.359 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	4.158SerAla: 4.158 ± 0.076	0.637SerCys: 0.637 ± 0.024	3.63SerAsp: 3.63 ± 0.058	4.621SerGlu: 4.621 ± 0.078	3.865SerPhe: 3.865 ± 0.062	4.856SerGly: 4.856 ± 0.106	1.075SerHis: 1.075 ± 0.034	4.788SerIle: 4.788 ± 0.069	5.072SerLys: 5.072 ± 0.084	5.961SerLeu: 5.961 ± 0.075	1.376SerMet: 1.376 ± 0.038	3.71SerAsn: 3.71 ± 0.077	2.184SerPro: 2.184 ± 0.047	2.492SerGln: 2.492 ± 0.055	2.093SerArg: 2.093 ± 0.044	4.517SerSer: 4.517 ± 0.087	3.508SerThr: 3.508 ± 0.081	4.414SerVal: 4.414 ± 0.068	0.701SerTrp: 0.701 ± 0.028	2.685SerTyr: 2.685 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	3.864ThrAla: 3.864 ± 0.099	0.346ThrCys: 0.346 ± 0.02	3.161ThrAsp: 3.161 ± 0.063	3.669ThrGlu: 3.669 ± 0.06	2.959ThrPhe: 2.959 ± 0.06	4.045ThrGly: 4.045 ± 0.091	0.878ThrHis: 0.878 ± 0.032	4.161ThrIle: 4.161 ± 0.07	3.744ThrLys: 3.744 ± 0.058	4.921ThrLeu: 4.921 ± 0.072	0.941ThrMet: 0.941 ± 0.03	3.086ThrAsn: 3.086 ± 0.075	2.345ThrPro: 2.345 ± 0.072	1.975ThrGln: 1.975 ± 0.055	1.544ThrArg: 1.544 ± 0.039	3.647ThrSer: 3.647 ± 0.092	3.243ThrThr: 3.243 ± 0.097	3.685ThrVal: 3.685 ± 0.067	0.509ThrTrp: 0.509 ± 0.024	2.226ThrTyr: 2.226 ± 0.061	0.0ThrXaa: 0.0 ± 0.0
Val	3.657ValAla: 3.657 ± 0.07	0.558ValCys: 0.558 ± 0.023	3.099ValAsp: 3.099 ± 0.061	3.744ValGlu: 3.744 ± 0.068	3.424ValPhe: 3.424 ± 0.06	3.593ValGly: 3.593 ± 0.07	0.837ValHis: 0.837 ± 0.03	4.739ValIle: 4.739 ± 0.073	4.833ValLys: 4.833 ± 0.071	5.402ValLeu: 5.402 ± 0.078	1.426ValMet: 1.426 ± 0.042	3.607ValAsn: 3.607 ± 0.066	2.087ValPro: 2.087 ± 0.046	1.838ValGln: 1.838 ± 0.044	1.895ValArg: 1.895 ± 0.047	4.418ValSer: 4.418 ± 0.065	3.378ValThr: 3.378 ± 0.077	3.663ValVal: 3.663 ± 0.07	0.586ValTrp: 0.586 ± 0.027	2.46ValTyr: 2.46 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.545TrpAla: 0.545 ± 0.026	0.097TrpCys: 0.097 ± 0.01	0.547TrpAsp: 0.547 ± 0.02	0.7TrpGlu: 0.7 ± 0.026	0.58TrpPhe: 0.58 ± 0.028	0.661TrpGly: 0.661 ± 0.033	0.171TrpHis: 0.171 ± 0.014	0.799TrpIle: 0.799 ± 0.031	0.982TrpLys: 0.982 ± 0.031	0.864TrpLeu: 0.864 ± 0.032	0.335TrpMet: 0.335 ± 0.017	0.755TrpAsn: 0.755 ± 0.03	0.156TrpPro: 0.156 ± 0.013	0.396TrpGln: 0.396 ± 0.021	0.348TrpArg: 0.348 ± 0.02	0.615TrpSer: 0.615 ± 0.022	0.522TrpThr: 0.522 ± 0.021	0.569TrpVal: 0.569 ± 0.027	0.13TrpTrp: 0.13 ± 0.012	0.414TrpTyr: 0.414 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.235TyrAla: 2.235 ± 0.051	0.374TyrCys: 0.374 ± 0.021	2.333TyrAsp: 2.333 ± 0.054	2.443TyrGlu: 2.443 ± 0.056	2.75TyrPhe: 2.75 ± 0.055	2.486TyrGly: 2.486 ± 0.055	0.816TyrHis: 0.816 ± 0.032	3.084TyrIle: 3.084 ± 0.052	2.955TyrLys: 2.955 ± 0.054	3.858TyrLeu: 3.858 ± 0.064	0.717TyrMet: 0.717 ± 0.025	2.64TyrAsn: 2.64 ± 0.07	1.477TyrPro: 1.477 ± 0.038	1.748TyrGln: 1.748 ± 0.045	1.637TyrArg: 1.637 ± 0.039	2.915TyrSer: 2.915 ± 0.069	2.235TyrThr: 2.235 ± 0.054	1.965TyrVal: 1.965 ± 0.037	0.472TyrTrp: 0.472 ± 0.025	2.052TyrTyr: 2.052 ± 0.054	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3186 proteins (1015609 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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