Amino acid dipepetide frequency for Commelina yellow mottle virus (CoYMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.604AlaAla: 3.604 ± 1.653
0.901AlaCys: 0.901 ± 0.413
0.901AlaAsp: 0.901 ± 0.413
4.955AlaGlu: 4.955 ± 2.273
1.802AlaPhe: 1.802 ± 0.826
2.703AlaGly: 2.703 ± 1.24
1.351AlaHis: 1.351 ± 2.427
7.207AlaIle: 7.207 ± 2.695
4.505AlaLys: 4.505 ± 4.785
4.054AlaLeu: 4.054 ± 2.175
2.703AlaMet: 2.703 ± 1.24
1.802AlaAsn: 1.802 ± 0.826
2.252AlaPro: 2.252 ± 3.648
3.604AlaGln: 3.604 ± 1.653
2.252AlaArg: 2.252 ± 1.523
3.604AlaSer: 3.604 ± 1.653
4.505AlaThr: 4.505 ± 1.381
4.955AlaVal: 4.955 ± 1.442
0.901AlaTrp: 0.901 ± 0.413
2.252AlaTyr: 2.252 ± 1.033
0.0AlaXaa: 0.0 ± 0.0
Cys
1.351CysAla: 1.351 ± 0.62
0.0CysCys: 0.0 ± 0.0
0.901CysAsp: 0.901 ± 0.413
0.45CysGlu: 0.45 ± 0.207
0.901CysPhe: 0.901 ± 1.148
0.45CysGly: 0.45 ± 0.207
1.351CysHis: 1.351 ± 0.62
0.0CysIle: 0.0 ± 0.0
2.703CysLys: 2.703 ± 1.24
0.45CysLeu: 0.45 ± 0.207
0.45CysMet: 0.45 ± 0.207
0.901CysAsn: 0.901 ± 0.413
0.45CysPro: 0.45 ± 0.207
0.0CysGln: 0.0 ± 0.0
1.351CysArg: 1.351 ± 0.62
0.45CysSer: 0.45 ± 0.207
0.45CysThr: 0.45 ± 0.207
0.45CysVal: 0.45 ± 0.207
0.0CysTrp: 0.0 ± 0.0
0.45CysTyr: 0.45 ± 0.207
0.0CysXaa: 0.0 ± 0.0
Asp
2.252AspAla: 2.252 ± 1.033
0.45AspCys: 0.45 ± 0.207
3.153AspAsp: 3.153 ± 1.446
7.658AspGlu: 7.658 ± 3.512
2.252AspPhe: 2.252 ± 1.033
4.054AspGly: 4.054 ± 1.859
0.45AspHis: 0.45 ± 0.207
4.054AspIle: 4.054 ± 1.098
2.252AspLys: 2.252 ± 1.033
4.505AspLeu: 4.505 ± 0.912
0.0AspMet: 0.0 ± 0.0
2.252AspAsn: 2.252 ± 1.033
3.153AspPro: 3.153 ± 1.486
3.153AspGln: 3.153 ± 1.977
2.252AspArg: 2.252 ± 1.523
1.351AspSer: 1.351 ± 0.62
1.802AspThr: 1.802 ± 0.826
2.703AspVal: 2.703 ± 1.685
0.45AspTrp: 0.45 ± 1.285
1.802AspTyr: 1.802 ± 0.952
0.0AspXaa: 0.0 ± 0.0
Glu
4.955GluAla: 4.955 ± 0.738
0.0GluCys: 0.0 ± 0.0
7.658GluAsp: 7.658 ± 0.665
17.568GluGlu: 17.568 ± 2.931
2.703GluPhe: 2.703 ± 1.24
3.604GluGly: 3.604 ± 1.653
1.802GluHis: 1.802 ± 0.826
6.757GluIle: 6.757 ± 1.904
6.757GluLys: 6.757 ± 0.495
4.955GluLeu: 4.955 ± 2.925
2.252GluMet: 2.252 ± 1.033
5.405GluAsn: 5.405 ± 1.636
2.252GluPro: 2.252 ± 1.033
3.153GluGln: 3.153 ± 1.977
4.054GluArg: 4.054 ± 1.348
6.306GluSer: 6.306 ± 0.438
4.955GluThr: 4.955 ± 2.273
4.054GluVal: 4.054 ± 3.101
0.45GluTrp: 0.45 ± 0.207
3.153GluTyr: 3.153 ± 1.446
0.0GluXaa: 0.0 ± 0.0
Phe
1.351PheAla: 1.351 ± 0.62
0.901PheCys: 0.901 ± 1.148
0.901PheAsp: 0.901 ± 0.413
1.351PheGlu: 1.351 ± 0.62
0.0PhePhe: 0.0 ± 0.0
1.351PheGly: 1.351 ± 0.62
0.901PheHis: 0.901 ± 0.413
3.604PheIle: 3.604 ± 1.053
3.604PheLys: 3.604 ± 2.378
3.604PheLeu: 3.604 ± 1.653
0.901PheMet: 0.901 ± 1.148
2.252PheAsn: 2.252 ± 1.523
1.351PhePro: 1.351 ± 1.034
1.351PheGln: 1.351 ± 0.62
2.252PheArg: 2.252 ± 1.033
3.604PheSer: 3.604 ± 1.653
1.802PheThr: 1.802 ± 0.952
0.45PheVal: 0.45 ± 0.207
0.901PheTrp: 0.901 ± 0.413
1.802PheTyr: 1.802 ± 0.826
0.0PheXaa: 0.0 ± 0.0
Gly
2.252GlyAla: 2.252 ± 1.523
1.351GlyCys: 1.351 ± 0.62
2.703GlyAsp: 2.703 ± 1.24
4.505GlyGlu: 4.505 ± 2.066
1.802GlyPhe: 1.802 ± 0.952
1.802GlyGly: 1.802 ± 1.63
0.45GlyHis: 0.45 ± 0.207
3.604GlyIle: 3.604 ± 1.347
3.604GlyLys: 3.604 ± 1.653
5.405GlyLeu: 5.405 ± 0.584
1.351GlyMet: 1.351 ± 1.034
1.351GlyAsn: 1.351 ± 0.62
2.252GlyPro: 2.252 ± 1.033
2.252GlyGln: 2.252 ± 1.033
3.604GlyArg: 3.604 ± 1.653
1.802GlySer: 1.802 ± 0.826
3.153GlyThr: 3.153 ± 1.446
4.955GlyVal: 4.955 ± 2.954
0.901GlyTrp: 0.901 ± 0.413
1.802GlyTyr: 1.802 ± 1.63
0.0GlyXaa: 0.0 ± 0.0
His
0.901HisAla: 0.901 ± 0.413
0.45HisCys: 0.45 ± 0.207
1.351HisAsp: 1.351 ± 0.62
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.351HisGly: 1.351 ± 0.62
0.901HisHis: 0.901 ± 0.413
3.153HisIle: 3.153 ± 0.964
0.901HisLys: 0.901 ± 0.413
1.802HisLeu: 1.802 ± 0.826
0.0HisMet: 0.0 ± 0.0
1.802HisAsn: 1.802 ± 0.952
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
3.153HisArg: 3.153 ± 0.964
1.802HisSer: 1.802 ± 0.952
0.901HisThr: 0.901 ± 1.148
0.901HisVal: 0.901 ± 0.413
0.0HisTrp: 0.0 ± 0.0
0.45HisTyr: 0.45 ± 0.207
0.0HisXaa: 0.0 ± 0.0
Ile
3.153IleAla: 3.153 ± 0.964
1.802IleCys: 1.802 ± 0.826
4.505IleAsp: 4.505 ± 1.312
6.757IleGlu: 6.757 ± 1.001
2.252IlePhe: 2.252 ± 0.91
4.505IleGly: 4.505 ± 3.046
2.252IleHis: 2.252 ± 2.175
8.108IleIle: 8.108 ± 0.539
6.757IleLys: 6.757 ± 2.717
4.955IleLeu: 4.955 ± 1.442
2.252IleMet: 2.252 ± 1.033
4.955IleAsn: 4.955 ± 1.469
1.351IlePro: 1.351 ± 0.62
5.856IleGln: 5.856 ± 0.473
3.153IleArg: 3.153 ± 1.446
5.405IleSer: 5.405 ± 4.987
3.604IleThr: 3.604 ± 3.261
4.054IleVal: 4.054 ± 1.851
0.45IleTrp: 0.45 ± 0.207
2.252IleTyr: 2.252 ± 1.885
0.0IleXaa: 0.0 ± 0.0
Lys
5.856LysAla: 5.856 ± 1.638
1.351LysCys: 1.351 ± 0.62
4.054LysAsp: 4.054 ± 1.859
8.559LysGlu: 8.559 ± 0.472
3.604LysPhe: 3.604 ± 1.29
3.604LysGly: 3.604 ± 1.29
3.604LysHis: 3.604 ± 1.653
6.757LysIle: 6.757 ± 1.001
5.405LysLys: 5.405 ± 2.782
6.757LysLeu: 6.757 ± 5.302
2.703LysMet: 2.703 ± 1.24
2.703LysAsn: 2.703 ± 0.915
1.802LysPro: 1.802 ± 0.826
4.505LysGln: 4.505 ± 4.738
1.351LysArg: 1.351 ± 1.756
3.153LysSer: 3.153 ± 1.977
0.901LysThr: 0.901 ± 1.895
4.955LysVal: 4.955 ± 3.145
0.901LysTrp: 0.901 ± 0.413
2.252LysTyr: 2.252 ± 1.033
0.0LysXaa: 0.0 ± 0.0
Leu
5.856LeuAla: 5.856 ± 3.171
0.45LeuCys: 0.45 ± 0.207
3.153LeuAsp: 3.153 ± 0.964
4.054LeuGlu: 4.054 ± 3.148
0.45LeuPhe: 0.45 ± 0.207
4.955LeuGly: 4.955 ± 1.813
0.901LeuHis: 0.901 ± 0.413
5.405LeuIle: 5.405 ± 1.829
7.207LeuLys: 7.207 ± 6.412
4.955LeuLeu: 4.955 ± 4.238
1.802LeuMet: 1.802 ± 0.826
3.604LeuAsn: 3.604 ± 1.29
4.054LeuPro: 4.054 ± 1.172
5.856LeuGln: 5.856 ± 0.473
3.604LeuArg: 3.604 ± 2.378
9.459LeuSer: 9.459 ± 5.092
3.153LeuThr: 3.153 ± 1.486
4.955LeuVal: 4.955 ± 1.774
0.0LeuTrp: 0.0 ± 0.0
2.252LeuTyr: 2.252 ± 0.91
0.0LeuXaa: 0.0 ± 0.0
Met
2.252MetAla: 2.252 ± 1.033
0.45MetCys: 0.45 ± 0.207
1.351MetAsp: 1.351 ± 0.62
2.703MetGlu: 2.703 ± 1.24
0.0MetPhe: 0.0 ± 0.0
1.351MetGly: 1.351 ± 0.62
0.0MetHis: 0.0 ± 0.0
1.802MetIle: 1.802 ± 0.826
3.604MetLys: 3.604 ± 1.653
1.351MetLeu: 1.351 ± 0.62
0.901MetMet: 0.901 ± 0.413
3.153MetAsn: 3.153 ± 1.977
1.802MetPro: 1.802 ± 0.826
1.351MetGln: 1.351 ± 0.62
1.802MetArg: 1.802 ± 0.826
0.901MetSer: 0.901 ± 1.895
1.802MetThr: 1.802 ± 0.826
2.703MetVal: 2.703 ± 0.915
0.45MetTrp: 0.45 ± 0.207
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.351AsnAla: 1.351 ± 0.62
0.45AsnCys: 0.45 ± 0.207
3.153AsnAsp: 3.153 ± 1.446
3.153AsnGlu: 3.153 ± 1.446
2.703AsnPhe: 2.703 ± 1.24
3.153AsnGly: 3.153 ± 1.446
1.802AsnHis: 1.802 ± 0.826
4.505AsnIle: 4.505 ± 1.974
3.153AsnLys: 3.153 ± 1.446
4.505AsnLeu: 4.505 ± 1.82
2.252AsnMet: 2.252 ± 0.884
0.901AsnAsn: 0.901 ± 1.895
3.153AsnPro: 3.153 ± 3.382
2.703AsnGln: 2.703 ± 0.915
0.0AsnArg: 0.0 ± 0.0
0.45AsnSer: 0.45 ± 0.207
2.252AsnThr: 2.252 ± 1.523
2.252AsnVal: 2.252 ± 0.91
0.45AsnTrp: 0.45 ± 0.207
4.955AsnTyr: 4.955 ± 2.954
0.0AsnXaa: 0.0 ± 0.0
Pro
4.955ProAla: 4.955 ± 2.954
0.0ProCys: 0.0 ± 0.0
2.252ProAsp: 2.252 ± 1.033
5.405ProGlu: 5.405 ± 0.584
0.901ProPhe: 0.901 ± 1.148
2.252ProGly: 2.252 ± 1.033
0.45ProHis: 0.45 ± 0.207
2.703ProIle: 2.703 ± 1.24
1.351ProLys: 1.351 ± 1.034
1.802ProLeu: 1.802 ± 3.711
0.901ProMet: 0.901 ± 0.413
1.351ProAsn: 1.351 ± 1.756
1.351ProPro: 1.351 ± 0.62
0.901ProGln: 0.901 ± 0.413
0.901ProArg: 0.901 ± 0.413
3.153ProSer: 3.153 ± 1.446
4.054ProThr: 4.054 ± 1.348
2.703ProVal: 2.703 ± 1.437
0.45ProTrp: 0.45 ± 0.207
1.351ProTyr: 1.351 ± 1.034
0.0ProXaa: 0.0 ± 0.0
Gln
4.054GlnAla: 4.054 ± 1.859
1.351GlnCys: 1.351 ± 0.62
2.252GlnAsp: 2.252 ± 1.885
5.405GlnGlu: 5.405 ± 2.479
0.901GlnPhe: 0.901 ± 0.413
0.901GlnGly: 0.901 ± 0.413
0.901GlnHis: 0.901 ± 0.413
5.405GlnIle: 5.405 ± 2.782
2.703GlnLys: 2.703 ± 3.443
4.955GlnLeu: 4.955 ± 0.738
2.252GlnMet: 2.252 ± 1.033
1.802GlnAsn: 1.802 ± 0.826
3.153GlnPro: 3.153 ± 0.964
2.252GlnGln: 2.252 ± 1.523
4.505GlnArg: 4.505 ± 0.912
4.505GlnSer: 4.505 ± 3.77
0.901GlnThr: 0.901 ± 1.148
3.153GlnVal: 3.153 ± 1.977
0.45GlnTrp: 0.45 ± 0.207
1.802GlnTyr: 1.802 ± 0.826
0.0GlnXaa: 0.0 ± 0.0
Arg
1.351ArgAla: 1.351 ± 1.756
1.351ArgCys: 1.351 ± 0.62
1.351ArgAsp: 1.351 ± 1.034
0.901ArgGlu: 0.901 ± 1.148
1.802ArgPhe: 1.802 ± 0.826
1.351ArgGly: 1.351 ± 0.62
0.901ArgHis: 0.901 ± 0.413
3.153ArgIle: 3.153 ± 1.486
3.604ArgLys: 3.604 ± 1.653
3.153ArgLeu: 3.153 ± 1.378
4.054ArgMet: 4.054 ± 1.809
2.703ArgAsn: 2.703 ± 1.24
1.802ArgPro: 1.802 ± 0.952
2.252ArgGln: 2.252 ± 1.523
4.955ArgArg: 4.955 ± 1.813
8.108ArgSer: 8.108 ± 2.755
2.252ArgThr: 2.252 ± 1.033
4.505ArgVal: 4.505 ± 3.111
1.802ArgTrp: 1.802 ± 0.826
0.901ArgTyr: 0.901 ± 0.413
0.0ArgXaa: 0.0 ± 0.0
Ser
4.505SerAla: 4.505 ± 1.312
0.45SerCys: 0.45 ± 0.207
3.604SerAsp: 3.604 ± 1.347
7.207SerGlu: 7.207 ± 3.807
4.505SerPhe: 4.505 ± 1.312
4.054SerGly: 4.054 ± 1.348
0.901SerHis: 0.901 ± 1.148
2.252SerIle: 2.252 ± 1.033
6.306SerLys: 6.306 ± 2.973
5.405SerLeu: 5.405 ± 3.37
0.901SerMet: 0.901 ± 0.413
3.604SerAsn: 3.604 ± 3.261
2.252SerPro: 2.252 ± 1.033
3.604SerGln: 3.604 ± 1.053
4.955SerArg: 4.955 ± 1.469
6.306SerSer: 6.306 ± 1.928
5.405SerThr: 5.405 ± 1.529
3.604SerVal: 3.604 ± 1.29
1.351SerTrp: 1.351 ± 0.62
1.351SerTyr: 1.351 ± 0.62
0.0SerXaa: 0.0 ± 0.0
Thr
4.054ThrAla: 4.054 ± 1.348
0.0ThrCys: 0.0 ± 0.0
2.252ThrAsp: 2.252 ± 1.523
5.856ThrGlu: 5.856 ± 1.38
2.252ThrPhe: 2.252 ± 1.033
4.955ThrGly: 4.955 ± 1.442
0.45ThrHis: 0.45 ± 0.207
4.955ThrIle: 4.955 ± 5.011
3.153ThrLys: 3.153 ± 1.378
1.351ThrLeu: 1.351 ± 0.62
0.901ThrMet: 0.901 ± 0.413
0.901ThrAsn: 0.901 ± 1.895
4.054ThrPro: 4.054 ± 2.175
3.153ThrGln: 3.153 ± 3.382
2.703ThrArg: 2.703 ± 1.24
4.955ThrSer: 4.955 ± 2.273
1.351ThrThr: 1.351 ± 1.756
1.802ThrVal: 1.802 ± 0.826
0.901ThrTrp: 0.901 ± 0.413
0.45ThrTyr: 0.45 ± 0.207
0.0ThrXaa: 0.0 ± 0.0
Val
3.153ValAla: 3.153 ± 2.581
1.351ValCys: 1.351 ± 0.62
2.252ValAsp: 2.252 ± 2.988
3.604ValGlu: 3.604 ± 1.904
4.505ValPhe: 4.505 ± 0.912
3.604ValGly: 3.604 ± 1.347
0.0ValHis: 0.0 ± 0.0
2.252ValIle: 2.252 ± 2.175
3.604ValLys: 3.604 ± 3.206
5.405ValLeu: 5.405 ± 1.829
1.802ValMet: 1.802 ± 0.826
4.054ValAsn: 4.054 ± 1.348
2.252ValPro: 2.252 ± 1.033
4.054ValGln: 4.054 ± 1.098
2.703ValArg: 2.703 ± 0.915
2.252ValSer: 2.252 ± 1.523
4.505ValThr: 4.505 ± 5.136
2.703ValVal: 2.703 ± 1.685
0.901ValTrp: 0.901 ± 1.148
2.252ValTyr: 2.252 ± 1.033
0.0ValXaa: 0.0 ± 0.0
Trp
0.901TrpAla: 0.901 ± 0.413
0.0TrpCys: 0.0 ± 0.0
0.45TrpAsp: 0.45 ± 0.207
0.45TrpGlu: 0.45 ± 0.207
0.0TrpPhe: 0.0 ± 0.0
0.45TrpGly: 0.45 ± 0.207
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.802TrpLys: 1.802 ± 0.826
2.252TrpLeu: 2.252 ± 2.175
0.45TrpMet: 0.45 ± 0.207
0.45TrpAsn: 0.45 ± 0.207
0.0TrpPro: 0.0 ± 0.0
0.901TrpGln: 0.901 ± 0.413
0.901TrpArg: 0.901 ± 0.413
1.802TrpSer: 1.802 ± 0.826
0.901TrpThr: 0.901 ± 0.413
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.703TyrAla: 2.703 ± 1.24
0.45TyrCys: 0.45 ± 0.207
1.802TyrAsp: 1.802 ± 0.826
2.252TyrGlu: 2.252 ± 1.033
0.901TyrPhe: 0.901 ± 0.413
0.45TyrGly: 0.45 ± 0.207
0.45TyrHis: 0.45 ± 0.207
2.703TyrIle: 2.703 ± 1.24
1.802TyrLys: 1.802 ± 1.63
4.505TyrLeu: 4.505 ± 4.785
0.45TyrMet: 0.45 ± 0.207
1.802TyrAsn: 1.802 ± 0.826
0.45TyrPro: 0.45 ± 0.207
2.703TyrGln: 2.703 ± 1.24
1.802TyrArg: 1.802 ± 0.826
3.153TyrSer: 3.153 ± 0.964
1.802TyrThr: 1.802 ± 1.63
1.351TyrVal: 1.351 ± 0.62
0.0TyrTrp: 0.0 ± 0.0
3.153TyrTyr: 3.153 ± 0.964
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2221 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski