Amino acid dipepetide frequency for Brochothrix campestris FSL F6-1037

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.04AlaAla: 8.04 ± 0.161	0.615AlaCys: 0.615 ± 0.033	4.998AlaAsp: 4.998 ± 0.121	5.455AlaGlu: 5.455 ± 0.114	3.71AlaPhe: 3.71 ± 0.077	5.716AlaGly: 5.716 ± 0.1	1.559AlaHis: 1.559 ± 0.056	7.12AlaIle: 7.12 ± 0.129	5.241AlaLys: 5.241 ± 0.114	8.704AlaLeu: 8.704 ± 0.114	2.395AlaMet: 2.395 ± 0.065	3.745AlaAsn: 3.745 ± 0.08	2.413AlaPro: 2.413 ± 0.073	3.478AlaGln: 3.478 ± 0.08	2.937AlaArg: 2.937 ± 0.072	4.698AlaSer: 4.698 ± 0.089	5.845AlaThr: 5.845 ± 0.102	6.599AlaVal: 6.599 ± 0.108	0.571AlaTrp: 0.571 ± 0.032	2.774AlaTyr: 2.774 ± 0.074	0.0AlaXaa: 0.0 ± 0.0
Cys	0.519CysAla: 0.519 ± 0.034	0.085CysCys: 0.085 ± 0.014	0.437CysAsp: 0.437 ± 0.027	0.426CysGlu: 0.426 ± 0.033	0.365CysPhe: 0.365 ± 0.026	0.649CysGly: 0.649 ± 0.034	0.191CysHis: 0.191 ± 0.015	0.439CysIle: 0.439 ± 0.028	0.271CysLys: 0.271 ± 0.021	0.825CysLeu: 0.825 ± 0.039	0.145CysMet: 0.145 ± 0.017	0.229CysAsn: 0.229 ± 0.022	0.262CysPro: 0.262 ± 0.021	0.295CysGln: 0.295 ± 0.023	0.297CysArg: 0.297 ± 0.025	0.428CysSer: 0.428 ± 0.027	0.319CysThr: 0.319 ± 0.022	0.48CysVal: 0.48 ± 0.03	0.058CysTrp: 0.058 ± 0.011	0.286CysTyr: 0.286 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	4.231AspAla: 4.231 ± 0.121	0.377AspCys: 0.377 ± 0.023	2.588AspAsp: 2.588 ± 0.067	4.338AspGlu: 4.338 ± 0.091	2.444AspPhe: 2.444 ± 0.065	3.383AspGly: 3.383 ± 0.079	0.857AspHis: 0.857 ± 0.038	3.827AspIle: 3.827 ± 0.082	3.349AspLys: 3.349 ± 0.084	4.554AspLeu: 4.554 ± 0.092	1.333AspMet: 1.333 ± 0.04	2.104AspAsn: 2.104 ± 0.066	1.518AspPro: 1.518 ± 0.047	1.594AspGln: 1.594 ± 0.051	1.775AspArg: 1.775 ± 0.055	2.653AspSer: 2.653 ± 0.07	3.033AspThr: 3.033 ± 0.076	4.234AspVal: 4.234 ± 0.085	0.576AspTrp: 0.576 ± 0.03	2.339AspTyr: 2.339 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	6.003GluAla: 6.003 ± 0.118	0.339GluCys: 0.339 ± 0.027	2.757GluAsp: 2.757 ± 0.073	4.056GluGlu: 4.056 ± 0.089	1.916GluPhe: 1.916 ± 0.056	3.661GluGly: 3.661 ± 0.075	1.258GluHis: 1.258 ± 0.047	4.362GluIle: 4.362 ± 0.098	4.573GluLys: 4.573 ± 0.098	6.412GluLeu: 6.412 ± 0.112	2.012GluMet: 2.012 ± 0.058	2.866GluAsn: 2.866 ± 0.074	1.9GluPro: 1.9 ± 0.073	3.753GluGln: 3.753 ± 0.088	3.375GluArg: 3.375 ± 0.073	2.91GluSer: 2.91 ± 0.085	4.557GluThr: 4.557 ± 0.107	4.52GluVal: 4.52 ± 0.091	0.628GluTrp: 0.628 ± 0.03	1.606GluTyr: 1.606 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	3.229PheAla: 3.229 ± 0.069	0.328PheCys: 0.328 ± 0.025	2.448PheAsp: 2.448 ± 0.066	2.755PheGlu: 2.755 ± 0.065	2.048PhePhe: 2.048 ± 0.077	3.039PheGly: 3.039 ± 0.078	0.645PheHis: 0.645 ± 0.032	3.764PheIle: 3.764 ± 0.085	2.836PheLys: 2.836 ± 0.073	3.772PheLeu: 3.772 ± 0.093	1.12PheMet: 1.12 ± 0.047	2.186PheAsn: 2.186 ± 0.058	1.341PhePro: 1.341 ± 0.044	1.226PheGln: 1.226 ± 0.043	1.22PheArg: 1.22 ± 0.048	2.956PheSer: 2.956 ± 0.076	2.498PheThr: 2.498 ± 0.061	3.186PheVal: 3.186 ± 0.083	0.391PheTrp: 0.391 ± 0.026	1.635PheTyr: 1.635 ± 0.063	0.0PheXaa: 0.0 ± 0.0
Gly	5.163GlyAla: 5.163 ± 0.108	0.578GlyCys: 0.578 ± 0.033	3.188GlyAsp: 3.188 ± 0.073	3.839GlyGlu: 3.839 ± 0.078	3.035GlyPhe: 3.035 ± 0.078	4.467GlyGly: 4.467 ± 0.119	1.343GlyHis: 1.343 ± 0.05	5.143GlyIle: 5.143 ± 0.108	4.199GlyLys: 4.199 ± 0.074	6.495GlyLeu: 6.495 ± 0.118	1.805GlyMet: 1.805 ± 0.059	2.41GlyAsn: 2.41 ± 0.066	1.507GlyPro: 1.507 ± 0.049	2.418GlyGln: 2.418 ± 0.058	2.545GlyArg: 2.545 ± 0.077	3.773GlySer: 3.773 ± 0.08	4.15GlyThr: 4.15 ± 0.089	5.077GlyVal: 5.077 ± 0.091	0.707GlyTrp: 0.707 ± 0.036	2.645GlyTyr: 2.645 ± 0.078	0.0GlyXaa: 0.0 ± 0.0
His	1.296HisAla: 1.296 ± 0.049	0.193HisCys: 0.193 ± 0.019	0.958HisAsp: 0.958 ± 0.038	1.177HisGlu: 1.177 ± 0.043	1.013HisPhe: 1.013 ± 0.04	1.28HisGly: 1.28 ± 0.051	0.593HisHis: 0.593 ± 0.036	1.297HisIle: 1.297 ± 0.045	0.893HisLys: 0.893 ± 0.037	2.14HisLeu: 2.14 ± 0.065	0.361HisMet: 0.361 ± 0.026	0.75HisAsn: 0.75 ± 0.036	0.975HisPro: 0.975 ± 0.038	1.0HisGln: 1.0 ± 0.039	0.95HisArg: 0.95 ± 0.04	1.06HisSer: 1.06 ± 0.042	1.068HisThr: 1.068 ± 0.043	1.33HisVal: 1.33 ± 0.05	0.208HisTrp: 0.208 ± 0.019	0.983HisTyr: 0.983 ± 0.036	0.0HisXaa: 0.0 ± 0.0
Ile	7.511IleAla: 7.511 ± 0.131	0.625IleCys: 0.625 ± 0.03	4.385IleAsp: 4.385 ± 0.095	5.167IleGlu: 5.167 ± 0.102	2.686IlePhe: 2.686 ± 0.082	5.627IleGly: 5.627 ± 0.098	1.28IleHis: 1.28 ± 0.048	5.629IleIle: 5.629 ± 0.118	4.551IleLys: 4.551 ± 0.101	5.752IleLeu: 5.752 ± 0.122	1.739IleMet: 1.739 ± 0.053	3.42IleAsn: 3.42 ± 0.076	2.758IlePro: 2.758 ± 0.056	2.459IleGln: 2.459 ± 0.06	2.779IleArg: 2.779 ± 0.057	4.513IleSer: 4.513 ± 0.083	5.004IleThr: 5.004 ± 0.083	5.765IleVal: 5.765 ± 0.103	0.559IleTrp: 0.559 ± 0.033	2.062IleTyr: 2.062 ± 0.058	0.0IleXaa: 0.0 ± 0.0
Lys	5.432LysAla: 5.432 ± 0.105	0.276LysCys: 0.276 ± 0.019	3.159LysAsp: 3.159 ± 0.084	4.622LysGlu: 4.622 ± 0.1	1.599LysPhe: 1.599 ± 0.045	3.779LysGly: 3.779 ± 0.089	1.176LysHis: 1.176 ± 0.045	4.155LysIle: 4.155 ± 0.08	5.119LysLys: 5.119 ± 0.12	5.271LysLeu: 5.271 ± 0.101	2.198LysMet: 2.198 ± 0.056	2.9LysAsn: 2.9 ± 0.074	1.998LysPro: 1.998 ± 0.065	3.476LysGln: 3.476 ± 0.075	3.301LysArg: 3.301 ± 0.066	3.082LysSer: 3.082 ± 0.085	4.556LysThr: 4.556 ± 0.1	4.404LysVal: 4.404 ± 0.096	0.664LysTrp: 0.664 ± 0.039	1.884LysTyr: 1.884 ± 0.063	0.0LysXaa: 0.0 ± 0.0
Leu	9.377LeuAla: 9.377 ± 0.121	0.709LeuCys: 0.709 ± 0.03	4.546LeuAsp: 4.546 ± 0.098	5.586LeuGlu: 5.586 ± 0.119	4.483LeuPhe: 4.483 ± 0.102	5.839LeuGly: 5.839 ± 0.114	1.726LeuHis: 1.726 ± 0.056	7.317LeuIle: 7.317 ± 0.131	6.203LeuLys: 6.203 ± 0.112	10.129LeuLeu: 10.129 ± 0.187	2.684LeuMet: 2.684 ± 0.069	4.57LeuAsn: 4.57 ± 0.087	4.204LeuPro: 4.204 ± 0.093	3.743LeuGln: 3.743 ± 0.079	3.497LeuArg: 3.497 ± 0.077	6.432LeuSer: 6.432 ± 0.096	7.171LeuThr: 7.171 ± 0.114	6.674LeuVal: 6.674 ± 0.109	0.672LeuTrp: 0.672 ± 0.032	2.88LeuTyr: 2.88 ± 0.073	0.0LeuXaa: 0.0 ± 0.0
Met	2.38MetAla: 2.38 ± 0.06	0.161MetCys: 0.161 ± 0.014	1.191MetAsp: 1.191 ± 0.04	1.19MetGlu: 1.19 ± 0.041	0.939MetPhe: 0.939 ± 0.044	1.67MetGly: 1.67 ± 0.051	0.497MetHis: 0.497 ± 0.025	2.094MetIle: 2.094 ± 0.063	2.14MetLys: 2.14 ± 0.059	2.514MetLeu: 2.514 ± 0.072	0.907MetMet: 0.907 ± 0.041	1.332MetAsn: 1.332 ± 0.049	1.136MetPro: 1.136 ± 0.042	0.982MetGln: 0.982 ± 0.041	1.139MetArg: 1.139 ± 0.048	1.849MetSer: 1.849 ± 0.051	2.309MetThr: 2.309 ± 0.062	1.767MetVal: 1.767 ± 0.055	0.155MetTrp: 0.155 ± 0.017	0.757MetTyr: 0.757 ± 0.037	0.0MetXaa: 0.0 ± 0.0
Asn	3.139AsnAla: 3.139 ± 0.067	0.344AsnCys: 0.344 ± 0.022	2.52AsnAsp: 2.52 ± 0.058	3.333AsnGlu: 3.333 ± 0.072	1.643AsnPhe: 1.643 ± 0.044	3.098AsnGly: 3.098 ± 0.073	1.027AsnHis: 1.027 ± 0.038	3.099AsnIle: 3.099 ± 0.073	2.975AsnLys: 2.975 ± 0.091	3.401AsnLeu: 3.401 ± 0.074	1.185AsnMet: 1.185 ± 0.043	2.122AsnAsn: 2.122 ± 0.075	1.812AsnPro: 1.812 ± 0.053	1.894AsnGln: 1.894 ± 0.057	2.026AsnArg: 2.026 ± 0.06	2.189AsnSer: 2.189 ± 0.065	2.443AsnThr: 2.443 ± 0.069	3.054AsnVal: 3.054 ± 0.086	0.484AsnTrp: 0.484 ± 0.026	1.842AsnTyr: 1.842 ± 0.054	0.0AsnXaa: 0.0 ± 0.0
Pro	2.769ProAla: 2.769 ± 0.063	0.161ProCys: 0.161 ± 0.019	1.693ProAsp: 1.693 ± 0.057	2.312ProGlu: 2.312 ± 0.077	1.816ProPhe: 1.816 ± 0.052	2.025ProGly: 2.025 ± 0.064	0.746ProHis: 0.746 ± 0.037	2.539ProIle: 2.539 ± 0.057	1.819ProLys: 1.819 ± 0.06	3.776ProLeu: 3.776 ± 0.071	0.781ProMet: 0.781 ± 0.038	1.441ProAsn: 1.441 ± 0.049	0.795ProPro: 0.795 ± 0.042	1.46ProGln: 1.46 ± 0.052	1.086ProArg: 1.086 ± 0.039	1.996ProSer: 1.996 ± 0.057	2.668ProThr: 2.668 ± 0.075	2.773ProVal: 2.773 ± 0.074	0.26ProTrp: 0.26 ± 0.019	1.267ProTyr: 1.267 ± 0.049	0.0ProXaa: 0.0 ± 0.0
Gln	4.07GlnAla: 4.07 ± 0.081	0.196GlnCys: 0.196 ± 0.018	1.311GlnAsp: 1.311 ± 0.048	1.933GlnGlu: 1.933 ± 0.056	1.775GlnPhe: 1.775 ± 0.051	1.952GlnGly: 1.952 ± 0.049	0.918GlnHis: 0.918 ± 0.039	2.553GlnIle: 2.553 ± 0.057	2.593GlnLys: 2.593 ± 0.067	5.679GlnLeu: 5.679 ± 0.111	1.168GlnMet: 1.168 ± 0.043	1.327GlnAsn: 1.327 ± 0.044	1.52GlnPro: 1.52 ± 0.052	2.848GlnGln: 2.848 ± 0.092	2.138GlnArg: 2.138 ± 0.062	2.288GlnSer: 2.288 ± 0.058	3.14GlnThr: 3.14 ± 0.07	2.765GlnVal: 2.765 ± 0.068	0.447GlnTrp: 0.447 ± 0.025	1.253GlnTyr: 1.253 ± 0.049	0.0GlnXaa: 0.0 ± 0.0
Arg	2.875ArgAla: 2.875 ± 0.069	0.309ArgCys: 0.309 ± 0.023	1.895ArgAsp: 1.895 ± 0.058	2.567ArgGlu: 2.567 ± 0.065	2.061ArgPhe: 2.061 ± 0.06	2.264ArgGly: 2.264 ± 0.06	0.926ArgHis: 0.926 ± 0.042	2.975ArgIle: 2.975 ± 0.075	2.436ArgLys: 2.436 ± 0.069	4.663ArgLeu: 4.663 ± 0.104	1.209ArgMet: 1.209 ± 0.053	1.521ArgAsn: 1.521 ± 0.047	1.291ArgPro: 1.291 ± 0.048	2.001ArgGln: 2.001 ± 0.057	2.009ArgArg: 2.009 ± 0.061	2.264ArgSer: 2.264 ± 0.064	2.111ArgThr: 2.111 ± 0.057	2.793ArgVal: 2.793 ± 0.071	0.357ArgTrp: 0.357 ± 0.022	1.788ArgTyr: 1.788 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	4.52SerAla: 4.52 ± 0.089	0.39SerCys: 0.39 ± 0.03	3.148SerAsp: 3.148 ± 0.074	3.671SerGlu: 3.671 ± 0.08	2.953SerPhe: 2.953 ± 0.072	4.182SerGly: 4.182 ± 0.086	1.161SerHis: 1.161 ± 0.046	3.997SerIle: 3.997 ± 0.085	3.222SerLys: 3.222 ± 0.081	5.829SerLeu: 5.829 ± 0.103	1.409SerMet: 1.409 ± 0.044	2.558SerAsn: 2.558 ± 0.063	1.805SerPro: 1.805 ± 0.051	2.288SerGln: 2.288 ± 0.06	2.23SerArg: 2.23 ± 0.055	3.432SerSer: 3.432 ± 0.075	3.511SerThr: 3.511 ± 0.096	4.267SerVal: 4.267 ± 0.075	0.567SerTrp: 0.567 ± 0.028	2.353SerTyr: 2.353 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	6.355ThrAla: 6.355 ± 0.108	0.352ThrCys: 0.352 ± 0.024	3.735ThrAsp: 3.735 ± 0.087	3.992ThrGlu: 3.992 ± 0.099	2.692ThrPhe: 2.692 ± 0.075	4.387ThrGly: 4.387 ± 0.09	1.322ThrHis: 1.322 ± 0.042	5.339ThrIle: 5.339 ± 0.087	3.937ThrLys: 3.937 ± 0.079	6.538ThrLeu: 6.538 ± 0.104	1.617ThrMet: 1.617 ± 0.051	3.035ThrAsn: 3.035 ± 0.071	2.714ThrPro: 2.714 ± 0.073	2.244ThrGln: 2.244 ± 0.05	2.263ThrArg: 2.263 ± 0.057	3.491ThrSer: 3.491 ± 0.075	4.935ThrThr: 4.935 ± 0.102	5.476ThrVal: 5.476 ± 0.131	0.453ThrTrp: 0.453 ± 0.029	2.427ThrTyr: 2.427 ± 0.065	0.0ThrXaa: 0.0 ± 0.0
Val	6.62ValAla: 6.62 ± 0.111	0.59ValCys: 0.59 ± 0.031	3.647ValAsp: 3.647 ± 0.082	4.332ValGlu: 4.332 ± 0.089	3.218ValPhe: 3.218 ± 0.082	4.766ValGly: 4.766 ± 0.098	1.171ValHis: 1.171 ± 0.05	6.001ValIle: 6.001 ± 0.092	4.606ValLys: 4.606 ± 0.082	7.18ValLeu: 7.18 ± 0.106	2.058ValMet: 2.058 ± 0.062	3.287ValAsn: 3.287 ± 0.075	2.643ValPro: 2.643 ± 0.065	2.184ValGln: 2.184 ± 0.062	2.503ValArg: 2.503 ± 0.068	4.985ValSer: 4.985 ± 0.079	5.413ValThr: 5.413 ± 0.117	5.79ValVal: 5.79 ± 0.096	0.557ValTrp: 0.557 ± 0.028	2.354ValTyr: 2.354 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.535TrpAla: 0.535 ± 0.027	0.068TrpCys: 0.068 ± 0.009	0.434TrpAsp: 0.434 ± 0.027	0.505TrpGlu: 0.505 ± 0.027	0.439TrpPhe: 0.439 ± 0.028	0.518TrpGly: 0.518 ± 0.032	0.235TrpHis: 0.235 ± 0.019	0.507TrpIle: 0.507 ± 0.03	0.436TrpLys: 0.436 ± 0.028	1.201TrpLeu: 1.201 ± 0.042	0.251TrpMet: 0.251 ± 0.024	0.352TrpAsn: 0.352 ± 0.021	0.227TrpPro: 0.227 ± 0.018	0.641TrpGln: 0.641 ± 0.037	0.415TrpArg: 0.415 ± 0.026	0.549TrpSer: 0.549 ± 0.029	0.475TrpThr: 0.475 ± 0.03	0.576TrpVal: 0.576 ± 0.032	0.122TrpTrp: 0.122 ± 0.015	0.298TrpTyr: 0.298 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.552TyrAla: 2.552 ± 0.067	0.309TyrCys: 0.309 ± 0.018	2.067TyrAsp: 2.067 ± 0.062	2.206TyrGlu: 2.206 ± 0.064	1.791TyrPhe: 1.791 ± 0.066	2.186TyrGly: 2.186 ± 0.055	0.893TyrHis: 0.893 ± 0.041	2.115TyrIle: 2.115 ± 0.06	1.652TyrLys: 1.652 ± 0.052	3.607TyrLeu: 3.607 ± 0.09	0.727TyrMet: 0.727 ± 0.034	1.475TyrAsn: 1.475 ± 0.046	1.365TyrPro: 1.365 ± 0.05	1.892TyrGln: 1.892 ± 0.06	1.832TyrArg: 1.832 ± 0.065	1.944TyrSer: 1.944 ± 0.065	2.097TyrThr: 2.097 ± 0.065	2.377TyrVal: 2.377 ± 0.069	0.346TyrTrp: 0.346 ± 0.021	1.379TyrTyr: 1.379 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2423 proteins (633698 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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