Amino acid dipepetide frequency for Prunus armeniaca (Apricot) (Armeniaca vulgaris)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.419AlaAla: 6.419 ± 0.035
1.297AlaCys: 1.297 ± 0.013
3.137AlaAsp: 3.137 ± 0.017
4.244AlaGlu: 4.244 ± 0.025
2.808AlaPhe: 2.808 ± 0.015
4.212AlaGly: 4.212 ± 0.026
1.402AlaHis: 1.402 ± 0.014
3.697AlaIle: 3.697 ± 0.02
3.973AlaLys: 3.973 ± 0.024
6.771AlaLeu: 6.771 ± 0.028
1.841AlaMet: 1.841 ± 0.013
2.594AlaAsn: 2.594 ± 0.015
2.96AlaPro: 2.96 ± 0.02
2.287AlaGln: 2.287 ± 0.014
3.396AlaArg: 3.396 ± 0.02
6.146AlaSer: 6.146 ± 0.027
3.661AlaThr: 3.661 ± 0.022
4.83AlaVal: 4.83 ± 0.027
0.814AlaTrp: 0.814 ± 0.01
1.823AlaTyr: 1.823 ± 0.015
0.0AlaXaa: 0.0 ± 0.0
Cys
1.039CysAla: 1.039 ± 0.009
0.539CysCys: 0.539 ± 0.008
0.866CysAsp: 0.866 ± 0.009
0.89CysGlu: 0.89 ± 0.01
0.927CysPhe: 0.927 ± 0.01
1.433CysGly: 1.433 ± 0.013
0.489CysHis: 0.489 ± 0.008
0.993CysIle: 0.993 ± 0.011
1.175CysLys: 1.175 ± 0.012
1.934CysLeu: 1.934 ± 0.013
0.474CysMet: 0.474 ± 0.007
0.86CysAsn: 0.86 ± 0.009
0.972CysPro: 0.972 ± 0.01
0.648CysGln: 0.648 ± 0.008
1.053CysArg: 1.053 ± 0.01
1.829CysSer: 1.829 ± 0.015
0.921CysThr: 0.921 ± 0.01
1.079CysVal: 1.079 ± 0.011
0.268CysTrp: 0.268 ± 0.005
0.547CysTyr: 0.547 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
3.422AspAla: 3.422 ± 0.02
0.968AspCys: 0.968 ± 0.011
3.605AspAsp: 3.605 ± 0.028
3.922AspGlu: 3.922 ± 0.024
2.327AspPhe: 2.327 ± 0.016
3.815AspGly: 3.815 ± 0.023
1.33AspHis: 1.33 ± 0.013
2.841AspIle: 2.841 ± 0.018
2.663AspLys: 2.663 ± 0.017
4.943AspLeu: 4.943 ± 0.022
1.33AspMet: 1.33 ± 0.012
2.019AspAsn: 2.019 ± 0.013
2.644AspPro: 2.644 ± 0.016
1.921AspGln: 1.921 ± 0.013
2.378AspArg: 2.378 ± 0.018
4.11AspSer: 4.11 ± 0.025
2.154AspThr: 2.154 ± 0.016
3.563AspVal: 3.563 ± 0.018
0.699AspTrp: 0.699 ± 0.008
1.527AspTyr: 1.527 ± 0.013
0.0AspXaa: 0.0 ± 0.0
Glu
4.933GluAla: 4.933 ± 0.027
0.909GluCys: 0.909 ± 0.01
3.986GluAsp: 3.986 ± 0.023
6.246GluGlu: 6.246 ± 0.035
2.335GluPhe: 2.335 ± 0.018
3.87GluGly: 3.87 ± 0.022
1.275GluHis: 1.275 ± 0.012
3.578GluIle: 3.578 ± 0.022
4.678GluLys: 4.678 ± 0.031
5.884GluLeu: 5.884 ± 0.034
1.736GluMet: 1.736 ± 0.014
3.031GluAsn: 3.031 ± 0.019
2.247GluPro: 2.247 ± 0.017
2.195GluGln: 2.195 ± 0.018
3.385GluArg: 3.385 ± 0.025
4.454GluSer: 4.454 ± 0.025
3.033GluThr: 3.033 ± 0.021
4.217GluVal: 4.217 ± 0.021
0.762GluTrp: 0.762 ± 0.009
1.602GluTyr: 1.602 ± 0.014
0.0GluXaa: 0.0 ± 0.0
Phe
2.485PheAla: 2.485 ± 0.016
0.933PheCys: 0.933 ± 0.01
2.336PheAsp: 2.336 ± 0.015
2.313PheGlu: 2.313 ± 0.015
1.952PhePhe: 1.952 ± 0.016
3.079PheGly: 3.079 ± 0.023
1.091PheHis: 1.091 ± 0.009
1.987PheIle: 1.987 ± 0.016
2.137PheLys: 2.137 ± 0.016
4.224PheLeu: 4.224 ± 0.025
0.99PheMet: 0.99 ± 0.01
1.752PheAsn: 1.752 ± 0.016
2.086PhePro: 2.086 ± 0.016
1.618PheGln: 1.618 ± 0.014
2.034PheArg: 2.034 ± 0.016
4.028PheSer: 4.028 ± 0.022
1.981PheThr: 1.981 ± 0.014
2.762PheVal: 2.762 ± 0.017
0.604PheTrp: 0.604 ± 0.008
1.262PheTyr: 1.262 ± 0.011
0.0PheXaa: 0.0 ± 0.0
Gly
4.02GlyAla: 4.02 ± 0.023
1.364GlyCys: 1.364 ± 0.013
3.423GlyAsp: 3.423 ± 0.022
3.655GlyGlu: 3.655 ± 0.023
3.251GlyPhe: 3.251 ± 0.024
5.859GlyGly: 5.859 ± 0.062
1.618GlyHis: 1.618 ± 0.014
3.557GlyIle: 3.557 ± 0.02
4.179GlyLys: 4.179 ± 0.02
6.165GlyLeu: 6.165 ± 0.029
1.574GlyMet: 1.574 ± 0.014
3.109GlyAsn: 3.109 ± 0.022
2.592GlyPro: 2.592 ± 0.02
2.196GlyGln: 2.196 ± 0.016
3.756GlyArg: 3.756 ± 0.021
6.108GlySer: 6.108 ± 0.027
3.236GlyThr: 3.236 ± 0.019
4.361GlyVal: 4.361 ± 0.027
0.987GlyTrp: 0.987 ± 0.011
2.024GlyTyr: 2.024 ± 0.019
0.0GlyXaa: 0.0 ± 0.0
His
1.474HisAla: 1.474 ± 0.013
0.528HisCys: 0.528 ± 0.007
1.205HisAsp: 1.205 ± 0.012
1.354HisGlu: 1.354 ± 0.011
1.062HisPhe: 1.062 ± 0.011
1.801HisGly: 1.801 ± 0.014
1.074HisHis: 1.074 ± 0.014
1.222HisIle: 1.222 ± 0.012
1.229HisLys: 1.229 ± 0.012
2.41HisLeu: 2.41 ± 0.015
0.595HisMet: 0.595 ± 0.007
1.036HisAsn: 1.036 ± 0.011
1.452HisPro: 1.452 ± 0.014
1.091HisGln: 1.091 ± 0.011
1.35HisArg: 1.35 ± 0.013
1.959HisSer: 1.959 ± 0.015
1.018HisThr: 1.018 ± 0.01
1.575HisVal: 1.575 ± 0.012
0.311HisTrp: 0.311 ± 0.006
0.706HisTyr: 0.706 ± 0.008
0.0HisXaa: 0.0 ± 0.0
Ile
3.499IleAla: 3.499 ± 0.023
1.088IleCys: 1.088 ± 0.011
2.721IleAsp: 2.721 ± 0.018
3.088IleGlu: 3.088 ± 0.019
2.213IlePhe: 2.213 ± 0.018
3.341IleGly: 3.341 ± 0.019
1.244IleHis: 1.244 ± 0.01
2.642IleIle: 2.642 ± 0.018
2.822IleLys: 2.822 ± 0.016
5.025IleLeu: 5.025 ± 0.024
1.141IleMet: 1.141 ± 0.01
2.135IleAsn: 2.135 ± 0.015
2.851IlePro: 2.851 ± 0.022
1.963IleGln: 1.963 ± 0.015
2.573IleArg: 2.573 ± 0.018
4.756IleSer: 4.756 ± 0.023
2.516IleThr: 2.516 ± 0.017
3.358IleVal: 3.358 ± 0.019
0.72IleTrp: 0.72 ± 0.01
1.454IleTyr: 1.454 ± 0.011
0.0IleXaa: 0.0 ± 0.0
Lys
4.175LysAla: 4.175 ± 0.026
0.991LysCys: 0.991 ± 0.01
3.203LysAsp: 3.203 ± 0.02
4.625LysGlu: 4.625 ± 0.029
2.189LysPhe: 2.189 ± 0.014
3.715LysGly: 3.715 ± 0.023
1.374LysHis: 1.374 ± 0.011
3.09LysIle: 3.09 ± 0.018
4.726LysLys: 4.726 ± 0.033
5.949LysLeu: 5.949 ± 0.028
1.512LysMet: 1.512 ± 0.013
2.617LysAsn: 2.617 ± 0.017
2.878LysPro: 2.878 ± 0.021
2.331LysGln: 2.331 ± 0.017
3.615LysArg: 3.615 ± 0.018
4.643LysSer: 4.643 ± 0.025
2.914LysThr: 2.914 ± 0.019
3.889LysVal: 3.889 ± 0.023
0.813LysTrp: 0.813 ± 0.009
1.612LysTyr: 1.612 ± 0.012
0.0LysXaa: 0.0 ± 0.0
Leu
6.536LeuAla: 6.536 ± 0.027
1.924LeuCys: 1.924 ± 0.014
4.979LeuAsp: 4.979 ± 0.023
6.287LeuGlu: 6.287 ± 0.035
3.803LeuPhe: 3.803 ± 0.025
6.061LeuGly: 6.061 ± 0.032
2.593LeuHis: 2.593 ± 0.016
4.559LeuIle: 4.559 ± 0.026
6.134LeuLys: 6.134 ± 0.029
9.854LeuLeu: 9.854 ± 0.042
2.168LeuMet: 2.168 ± 0.013
3.889LeuAsn: 3.889 ± 0.02
5.209LeuPro: 5.209 ± 0.025
4.265LeuGln: 4.265 ± 0.025
5.347LeuArg: 5.347 ± 0.026
8.456LeuSer: 8.456 ± 0.037
4.43LeuThr: 4.43 ± 0.026
6.435LeuVal: 6.435 ± 0.028
1.189LeuTrp: 1.189 ± 0.011
2.483LeuTyr: 2.483 ± 0.017
0.0LeuXaa: 0.0 ± 0.0
Met
2.237MetAla: 2.237 ± 0.016
0.342MetCys: 0.342 ± 0.006
1.407MetAsp: 1.407 ± 0.011
2.007MetGlu: 2.007 ± 0.015
0.811MetPhe: 0.811 ± 0.009
1.722MetGly: 1.722 ± 0.014
0.55MetHis: 0.55 ± 0.007
1.133MetIle: 1.133 ± 0.011
1.632MetLys: 1.632 ± 0.013
2.165MetLeu: 2.165 ± 0.017
0.686MetMet: 0.686 ± 0.008
0.997MetAsn: 0.997 ± 0.011
1.096MetPro: 1.096 ± 0.011
0.942MetGln: 0.942 ± 0.01
1.234MetArg: 1.234 ± 0.012
1.795MetSer: 1.795 ± 0.013
1.05MetThr: 1.05 ± 0.011
1.724MetVal: 1.724 ± 0.014
0.275MetTrp: 0.275 ± 0.006
0.557MetTyr: 0.557 ± 0.008
0.0MetXaa: 0.0 ± 0.0
Asn
2.685AsnAla: 2.685 ± 0.018
0.869AsnCys: 0.869 ± 0.009
2.012AsnAsp: 2.012 ± 0.017
2.461AsnGlu: 2.461 ± 0.017
1.921AsnPhe: 1.921 ± 0.013
3.29AsnGly: 3.29 ± 0.022
1.122AsnHis: 1.122 ± 0.01
2.365AsnIle: 2.365 ± 0.016
2.409AsnLys: 2.409 ± 0.017
4.467AsnLeu: 4.467 ± 0.03
1.108AsnMet: 1.108 ± 0.01
2.31AsnAsn: 2.31 ± 0.021
2.514AsnPro: 2.514 ± 0.019
1.712AsnGln: 1.712 ± 0.015
1.975AsnArg: 1.975 ± 0.016
3.951AsnSer: 3.951 ± 0.023
1.985AsnThr: 1.985 ± 0.015
2.775AsnVal: 2.775 ± 0.019
0.599AsnTrp: 0.599 ± 0.009
1.314AsnTyr: 1.314 ± 0.012
0.0AsnXaa: 0.0 ± 0.0
Pro
3.138ProAla: 3.138 ± 0.021
0.837ProCys: 0.837 ± 0.01
2.466ProAsp: 2.466 ± 0.016
3.116ProGlu: 3.116 ± 0.019
2.015ProPhe: 2.015 ± 0.014
2.74ProGly: 2.74 ± 0.021
1.216ProHis: 1.216 ± 0.012
2.423ProIle: 2.423 ± 0.017
2.921ProLys: 2.921 ± 0.021
4.418ProLeu: 4.418 ± 0.024
1.011ProMet: 1.011 ± 0.011
2.482ProAsn: 2.482 ± 0.017
4.239ProPro: 4.239 ± 0.081
1.969ProGln: 1.969 ± 0.016
2.435ProArg: 2.435 ± 0.017
5.311ProSer: 5.311 ± 0.035
2.832ProThr: 2.832 ± 0.02
3.066ProVal: 3.066 ± 0.017
0.629ProTrp: 0.629 ± 0.009
1.368ProTyr: 1.368 ± 0.015
0.0ProXaa: 0.0 ± 0.0
Gln
2.526GlnAla: 2.526 ± 0.019
0.61GlnCys: 0.61 ± 0.009
1.714GlnAsp: 1.714 ± 0.015
2.442GlnGlu: 2.442 ± 0.018
1.417GlnPhe: 1.417 ± 0.012
2.261GlnGly: 2.261 ± 0.019
0.98GlnHis: 0.98 ± 0.01
1.996GlnIle: 1.996 ± 0.014
2.384GlnLys: 2.384 ± 0.017
3.719GlnLeu: 3.719 ± 0.021
0.998GlnMet: 0.998 ± 0.011
1.872GlnAsn: 1.872 ± 0.014
1.937GlnPro: 1.937 ± 0.017
2.218GlnGln: 2.218 ± 0.031
2.151GlnArg: 2.151 ± 0.016
2.985GlnSer: 2.985 ± 0.019
1.823GlnThr: 1.823 ± 0.014
2.452GlnVal: 2.452 ± 0.017
0.49GlnTrp: 0.49 ± 0.007
0.941GlnTyr: 0.941 ± 0.009
0.0GlnXaa: 0.0 ± 0.0
Arg
3.335ArgAla: 3.335 ± 0.02
0.975ArgCys: 0.975 ± 0.01
2.578ArgAsp: 2.578 ± 0.018
3.324ArgGlu: 3.324 ± 0.024
2.18ArgPhe: 2.18 ± 0.015
3.324ArgGly: 3.324 ± 0.022
1.308ArgHis: 1.308 ± 0.013
2.719ArgIle: 2.719 ± 0.017
3.753ArgLys: 3.753 ± 0.023
4.985ArgLeu: 4.985 ± 0.021
1.302ArgMet: 1.302 ± 0.012
2.395ArgAsn: 2.395 ± 0.013
2.454ArgPro: 2.454 ± 0.019
1.9ArgGln: 1.9 ± 0.015
3.908ArgArg: 3.908 ± 0.027
4.319ArgSer: 4.319 ± 0.023
2.495ArgThr: 2.495 ± 0.017
3.388ArgVal: 3.388 ± 0.019
0.752ArgTrp: 0.752 ± 0.009
1.407ArgTyr: 1.407 ± 0.013
0.0ArgXaa: 0.0 ± 0.0
Ser
5.499SerAla: 5.499 ± 0.029
1.75SerCys: 1.75 ± 0.014
4.363SerAsp: 4.363 ± 0.024
4.75SerGlu: 4.75 ± 0.029
3.855SerPhe: 3.855 ± 0.02
5.914SerGly: 5.914 ± 0.032
2.078SerHis: 2.078 ± 0.015
4.361SerIle: 4.361 ± 0.021
4.943SerLys: 4.943 ± 0.024
8.622SerLeu: 8.622 ± 0.032
2.083SerMet: 2.083 ± 0.014
4.08SerAsn: 4.08 ± 0.023
4.714SerPro: 4.714 ± 0.039
3.133SerGln: 3.133 ± 0.021
4.378SerArg: 4.378 ± 0.022
11.09SerSer: 11.09 ± 0.056
4.786SerThr: 4.786 ± 0.023
5.261SerVal: 5.261 ± 0.024
1.209SerTrp: 1.209 ± 0.012
2.293SerTyr: 2.293 ± 0.016
0.0SerXaa: 0.0 ± 0.0
Thr
3.401ThrAla: 3.401 ± 0.018
0.949ThrCys: 0.949 ± 0.01
2.238ThrAsp: 2.238 ± 0.015
2.79ThrGlu: 2.79 ± 0.018
2.046ThrPhe: 2.046 ± 0.017
3.221ThrGly: 3.221 ± 0.019
1.097ThrHis: 1.097 ± 0.011
2.662ThrIle: 2.662 ± 0.017
2.77ThrLys: 2.77 ± 0.019
4.695ThrLeu: 4.695 ± 0.022
1.166ThrMet: 1.166 ± 0.01
2.101ThrAsn: 2.101 ± 0.014
2.677ThrPro: 2.677 ± 0.02
1.708ThrGln: 1.708 ± 0.013
2.398ThrArg: 2.398 ± 0.015
4.645ThrSer: 4.645 ± 0.025
3.156ThrThr: 3.156 ± 0.022
3.317ThrVal: 3.317 ± 0.017
0.687ThrTrp: 0.687 ± 0.008
1.378ThrTyr: 1.378 ± 0.013
0.0ThrXaa: 0.0 ± 0.0
Val
4.893ValAla: 4.893 ± 0.021
1.201ValCys: 1.201 ± 0.011
3.705ValAsp: 3.705 ± 0.019
4.475ValGlu: 4.475 ± 0.025
2.73ValPhe: 2.73 ± 0.016
4.437ValGly: 4.437 ± 0.03
1.575ValHis: 1.575 ± 0.014
3.265ValIle: 3.265 ± 0.021
3.838ValLys: 3.838 ± 0.022
6.41ValLeu: 6.41 ± 0.028
1.568ValMet: 1.568 ± 0.013
2.563ValAsn: 2.563 ± 0.016
3.303ValPro: 3.303 ± 0.018
2.386ValGln: 2.386 ± 0.016
3.141ValArg: 3.141 ± 0.017
5.361ValSer: 5.361 ± 0.025
3.173ValThr: 3.173 ± 0.019
5.159ValVal: 5.159 ± 0.028
0.811ValTrp: 0.811 ± 0.01
1.881ValTyr: 1.881 ± 0.014
0.0ValXaa: 0.0 ± 0.0
Trp
0.806TrpAla: 0.806 ± 0.009
0.244TrpCys: 0.244 ± 0.005
0.716TrpAsp: 0.716 ± 0.01
0.799TrpGlu: 0.799 ± 0.009
0.567TrpPhe: 0.567 ± 0.007
0.817TrpGly: 0.817 ± 0.011
0.315TrpHis: 0.315 ± 0.006
0.672TrpIle: 0.672 ± 0.008
0.947TrpLys: 0.947 ± 0.01
1.29TrpLeu: 1.29 ± 0.01
0.353TrpMet: 0.353 ± 0.006
0.695TrpAsn: 0.695 ± 0.009
0.539TrpPro: 0.539 ± 0.007
0.459TrpGln: 0.459 ± 0.007
0.869TrpArg: 0.869 ± 0.01
1.005TrpSer: 1.005 ± 0.01
0.651TrpThr: 0.651 ± 0.008
0.929TrpVal: 0.929 ± 0.011
0.272TrpTrp: 0.272 ± 0.006
0.35TrpTyr: 0.35 ± 0.006
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.791TyrAla: 1.791 ± 0.016
0.621TyrCys: 0.621 ± 0.008
1.519TyrAsp: 1.519 ± 0.01
1.564TyrGlu: 1.564 ± 0.013
1.246TyrPhe: 1.246 ± 0.011
2.119TyrGly: 2.119 ± 0.017
0.726TyrHis: 0.726 ± 0.009
1.385TyrIle: 1.385 ± 0.012
1.548TyrLys: 1.548 ± 0.014
2.673TyrLeu: 2.673 ± 0.018
0.727TyrMet: 0.727 ± 0.008
1.306TyrAsn: 1.306 ± 0.012
1.265TyrPro: 1.265 ± 0.013
0.974TyrGln: 0.974 ± 0.011
1.425TyrArg: 1.425 ± 0.012
2.211TyrSer: 2.211 ± 0.016
1.286TyrThr: 1.286 ± 0.013
1.734TyrVal: 1.734 ± 0.015
0.406TyrTrp: 0.406 ± 0.007
0.939TyrTyr: 0.939 ± 0.013
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 30031 proteins (10449125 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski