Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus)

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus; Human betaherpesvirus 7

Average proteome isoelectric point is 7.13

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 103 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q69516|Q69516_HHV7J U91 protein OS=Human herpesvirus 7 (strain JI) OX=57278 GN=U91 PE=4 SV=1
FF1 pKa = 7.55LCNKK5 pKa = 9.62IYY7 pKa = 10.66KK8 pKa = 9.98FYY10 pKa = 11.01YY11 pKa = 9.56RR12 pKa = 11.84YY13 pKa = 10.28HH14 pKa = 7.32PDD16 pKa = 3.06TTVEE20 pKa = 3.83EE21 pKa = 4.53TIRR24 pKa = 11.84DD25 pKa = 3.62ILQDD29 pKa = 3.66SLKK32 pKa = 10.71CNPSFDD38 pKa = 3.44NTLFQEE44 pKa = 4.37LDD46 pKa = 3.37SFDD49 pKa = 4.41FLDD52 pKa = 4.82SISSNDD58 pKa = 2.98IATANASYY66 pKa = 8.8STNVEE71 pKa = 4.0EE72 pKa = 5.51GASSDD77 pKa = 3.12IKK79 pKa = 10.68LAAGIFFSFSYY90 pKa = 10.39II91 pKa = 3.47

Molecular weight: 10.39 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P52339|DNBI_HHV7J Major DNA-binding protein OS=Human herpesvirus 7 (strain JI) OX=57278 GN=DBP PE=3 SV=1
MM1 pKa = 6.95SAEE4 pKa = 4.19MLRR7 pKa = 11.84AVQLQPRR14 pKa = 11.84RR15 pKa = 11.84RR16 pKa = 11.84GHH18 pKa = 5.85SSSPTSPPLEE28 pKa = 4.56GEE30 pKa = 4.17PSPKK34 pKa = 9.78RR35 pKa = 11.84LQSSDD40 pKa = 2.74SHH42 pKa = 6.09QGRR45 pKa = 11.84RR46 pKa = 11.84GRR48 pKa = 11.84PKK50 pKa = 9.97PRR52 pKa = 11.84AKK54 pKa = 9.23TWSEE58 pKa = 3.87ALSHH62 pKa = 7.01RR63 pKa = 11.84SFLNIYY69 pKa = 9.77AWLSLSRR76 pKa = 11.84GSPRR80 pKa = 11.84KK81 pKa = 8.87VYY83 pKa = 10.36GYY85 pKa = 10.83AFRR88 pKa = 11.84HH89 pKa = 5.73RR90 pKa = 11.84GEE92 pKa = 4.7LVALPWPPNWSLEE105 pKa = 4.13LHH107 pKa = 6.59HH108 pKa = 7.38DD109 pKa = 4.1PYY111 pKa = 11.35RR112 pKa = 11.84DD113 pKa = 3.33ARR115 pKa = 11.84AQTVWSHH122 pKa = 4.52RR123 pKa = 11.84WGWPATHH130 pKa = 5.14VTARR134 pKa = 11.84TVRR137 pKa = 11.84DD138 pKa = 3.53CGEE141 pKa = 4.35CKK143 pKa = 10.26QCDD146 pKa = 3.68TLLSQLSYY154 pKa = 10.55PINFLLMYY162 pKa = 10.54

Molecular weight: 18.73 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

102

1

103

41920

73

2059

407.0

46.82

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.299 ± 0.143

2.479 ± 0.152

4.699 ± 0.128

5.799 ± 0.135

6.233 ± 0.188

3.516 ± 0.145

2.543 ± 0.091

7.552 ± 0.245

7.226 ± 0.214

10.725 ± 0.291

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.197 ± 0.099

6.467 ± 0.193

3.969 ± 0.232

3.831 ± 0.142

4.07 ± 0.17

8.037 ± 0.283

6.333 ± 0.191

5.401 ± 0.17

0.802 ± 0.058

3.822 ± 0.14
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski