Amino acid dipepetide frequency for Lujo mammarenavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.198AlaAla: 1.198 ± 0.351
1.198AlaCys: 1.198 ± 0.874
1.497AlaAsp: 1.497 ± 0.22
1.796AlaGlu: 1.796 ± 0.831
0.898AlaPhe: 0.898 ± 0.485
0.898AlaGly: 0.898 ± 0.313
2.096AlaHis: 2.096 ± 0.793
2.994AlaIle: 2.994 ± 1.591
2.994AlaLys: 2.994 ± 1.832
2.096AlaLeu: 2.096 ± 0.76
0.599AlaMet: 0.599 ± 0.323
0.599AlaAsn: 0.599 ± 0.323
2.395AlaPro: 2.395 ± 1.469
0.599AlaGln: 0.599 ± 0.323
1.796AlaArg: 1.796 ± 1.089
4.192AlaSer: 4.192 ± 1.211
1.198AlaThr: 1.198 ± 0.729
2.695AlaVal: 2.695 ± 1.501
0.0AlaTrp: 0.0 ± 0.0
0.898AlaTyr: 0.898 ± 0.485
0.0AlaXaa: 0.0 ± 0.0
Cys
0.898CysAla: 0.898 ± 0.5
0.299CysCys: 0.299 ± 0.162
2.096CysAsp: 2.096 ± 0.592
1.497CysGlu: 1.497 ± 0.808
2.994CysPhe: 2.994 ± 1.236
1.497CysGly: 1.497 ± 0.805
0.898CysHis: 0.898 ± 0.313
3.293CysIle: 3.293 ± 0.642
0.898CysLys: 0.898 ± 0.716
2.695CysLeu: 2.695 ± 2.106
0.0CysMet: 0.0 ± 0.0
1.796CysAsn: 1.796 ± 1.873
1.198CysPro: 1.198 ± 0.786
0.599CysGln: 0.599 ± 0.364
0.599CysArg: 0.599 ± 0.323
1.497CysSer: 1.497 ± 0.22
0.599CysThr: 0.599 ± 0.656
1.796CysVal: 1.796 ± 0.554
0.898CysTrp: 0.898 ± 0.869
0.898CysTyr: 0.898 ± 1.549
0.0CysXaa: 0.0 ± 0.0
Asp
2.395AspAla: 2.395 ± 0.793
1.198AspCys: 1.198 ± 0.34
4.491AspAsp: 4.491 ± 1.33
5.689AspGlu: 5.689 ± 0.969
3.593AspPhe: 3.593 ± 0.553
1.796AspGly: 1.796 ± 0.554
1.198AspHis: 1.198 ± 1.494
3.892AspIle: 3.892 ± 1.024
3.593AspLys: 3.593 ± 0.321
8.982AspLeu: 8.982 ± 0.654
2.695AspMet: 2.695 ± 1.037
1.198AspAsn: 1.198 ± 0.351
1.796AspPro: 1.796 ± 0.626
2.395AspGln: 2.395 ± 0.966
2.096AspArg: 2.096 ± 0.835
5.09AspSer: 5.09 ± 1.497
2.695AspThr: 2.695 ± 1.084
3.593AspVal: 3.593 ± 1.677
1.497AspTrp: 1.497 ± 0.808
2.695AspTyr: 2.695 ± 0.521
0.0AspXaa: 0.0 ± 0.0
Glu
5.09GluAla: 5.09 ± 1.722
1.198GluCys: 1.198 ± 0.647
4.79GluAsp: 4.79 ± 0.741
4.79GluGlu: 4.79 ± 1.635
2.994GluPhe: 2.994 ± 1.078
3.593GluGly: 3.593 ± 1.109
2.096GluHis: 2.096 ± 0.793
2.695GluIle: 2.695 ± 0.293
3.293GluLys: 3.293 ± 0.35
6.886GluLeu: 6.886 ± 2.032
0.898GluMet: 0.898 ± 0.443
3.593GluAsn: 3.593 ± 0.994
2.096GluPro: 2.096 ± 0.633
1.796GluGln: 1.796 ± 0.658
3.593GluArg: 3.593 ± 1.047
6.587GluSer: 6.587 ± 2.602
3.892GluThr: 3.892 ± 1.332
3.293GluVal: 3.293 ± 0.424
0.299GluTrp: 0.299 ± 0.162
2.096GluTyr: 2.096 ± 0.835
0.0GluXaa: 0.0 ± 0.0
Phe
0.299PheAla: 0.299 ± 0.492
2.096PheCys: 2.096 ± 1.065
2.695PheAsp: 2.695 ± 1.206
2.994PheGlu: 2.994 ± 1.148
1.796PhePhe: 1.796 ± 0.658
0.599PheGly: 0.599 ± 0.364
0.599PheHis: 0.599 ± 0.419
2.695PheIle: 2.695 ± 0.993
5.09PheLys: 5.09 ± 1.796
5.988PheLeu: 5.988 ± 1.9
0.898PheMet: 0.898 ± 0.485
2.096PheAsn: 2.096 ± 1.219
3.593PhePro: 3.593 ± 0.321
1.796PheGln: 1.796 ± 1.275
1.796PheArg: 1.796 ± 0.161
4.79PheSer: 4.79 ± 0.699
4.491PheThr: 4.491 ± 1.081
4.192PheVal: 4.192 ± 1.779
0.299PheTrp: 0.299 ± 0.492
1.796PheTyr: 1.796 ± 0.161
0.0PheXaa: 0.0 ± 0.0
Gly
1.497GlyAla: 1.497 ± 0.43
0.599GlyCys: 0.599 ± 0.323
2.695GlyAsp: 2.695 ± 0.521
2.994GlyGlu: 2.994 ± 0.327
2.695GlyPhe: 2.695 ± 0.977
1.796GlyGly: 1.796 ± 0.161
0.599GlyHis: 0.599 ± 0.419
2.994GlyIle: 2.994 ± 0.721
1.796GlyLys: 1.796 ± 1.168
5.09GlyLeu: 5.09 ± 0.792
1.497GlyMet: 1.497 ± 1.185
2.395GlyAsn: 2.395 ± 0.841
2.096GlyPro: 2.096 ± 0.76
2.395GlyGln: 2.395 ± 1.49
3.593GlyArg: 3.593 ± 1.602
3.293GlySer: 3.293 ± 0.962
2.395GlyThr: 2.395 ± 0.342
4.491GlyVal: 4.491 ± 0.732
0.898GlyTrp: 0.898 ± 0.5
1.198GlyTyr: 1.198 ± 0.34
0.0GlyXaa: 0.0 ± 0.0
His
0.299HisAla: 0.299 ± 0.162
0.898HisCys: 0.898 ± 1.06
1.497HisAsp: 1.497 ± 1.314
0.898HisGlu: 0.898 ± 0.716
1.198HisPhe: 1.198 ± 0.351
1.198HisGly: 1.198 ± 0.34
0.898HisHis: 0.898 ± 0.402
1.497HisIle: 1.497 ± 0.539
0.898HisLys: 0.898 ± 0.485
2.695HisLeu: 2.695 ± 0.845
0.599HisMet: 0.599 ± 0.366
2.695HisAsn: 2.695 ± 0.977
1.497HisPro: 1.497 ± 0.22
0.898HisGln: 0.898 ± 0.313
1.796HisArg: 1.796 ± 1.257
2.695HisSer: 2.695 ± 1.625
0.898HisThr: 0.898 ± 0.5
0.898HisVal: 0.898 ± 0.485
0.0HisTrp: 0.0 ± 0.0
2.096HisTyr: 2.096 ± 0.721
0.0HisXaa: 0.0 ± 0.0
Ile
1.497IleAla: 1.497 ± 0.795
1.796IleCys: 1.796 ± 0.161
4.192IleAsp: 4.192 ± 1.186
3.593IleGlu: 3.593 ± 0.585
3.293IlePhe: 3.293 ± 0.886
1.497IleGly: 1.497 ± 0.43
1.497IleHis: 1.497 ± 0.539
1.497IleIle: 1.497 ± 1.314
4.79IleLys: 4.79 ± 0.741
5.389IleLeu: 5.389 ± 1.592
2.695IleMet: 2.695 ± 0.293
4.192IleAsn: 4.192 ± 1.184
2.994IlePro: 2.994 ± 1.611
1.796IleGln: 1.796 ± 0.682
2.994IleArg: 2.994 ± 1.148
5.689IleSer: 5.689 ± 1.627
5.09IleThr: 5.09 ± 0.629
3.293IleVal: 3.293 ± 0.922
0.0IleTrp: 0.0 ± 0.0
1.198IleTyr: 1.198 ± 0.34
0.0IleXaa: 0.0 ± 0.0
Lys
2.994LysAla: 2.994 ± 1.184
3.593LysCys: 3.593 ± 1.596
4.192LysAsp: 4.192 ± 1.587
5.988LysGlu: 5.988 ± 0.816
5.988LysPhe: 5.988 ± 0.878
4.192LysGly: 4.192 ± 0.918
2.096LysHis: 2.096 ± 0.235
2.994LysIle: 2.994 ± 1.148
5.389LysLys: 5.389 ± 1.417
8.683LysLeu: 8.683 ± 0.967
0.299LysMet: 0.299 ± 0.162
5.689LysAsn: 5.689 ± 0.737
0.898LysPro: 0.898 ± 0.869
1.497LysGln: 1.497 ± 0.43
2.695LysArg: 2.695 ± 0.526
8.683LysSer: 8.683 ± 1.25
4.491LysThr: 4.491 ± 1.474
4.79LysVal: 4.79 ± 0.839
0.898LysTrp: 0.898 ± 0.485
1.796LysTyr: 1.796 ± 0.554
0.0LysXaa: 0.0 ± 0.0
Leu
3.892LeuAla: 3.892 ± 1.132
3.892LeuCys: 3.892 ± 0.576
5.988LeuAsp: 5.988 ± 1.53
8.084LeuGlu: 8.084 ± 1.563
5.389LeuPhe: 5.389 ± 2.111
4.79LeuGly: 4.79 ± 0.761
2.096LeuHis: 2.096 ± 1.404
6.886LeuIle: 6.886 ± 1.828
10.18LeuLys: 10.18 ± 2.317
13.473LeuLeu: 13.473 ± 1.693
5.09LeuMet: 5.09 ± 3.5
8.383LeuAsn: 8.383 ± 1.667
3.892LeuPro: 3.892 ± 1.56
3.593LeuGln: 3.593 ± 0.923
5.988LeuArg: 5.988 ± 1.129
13.174LeuSer: 13.174 ± 1.809
4.192LeuThr: 4.192 ± 1.473
5.389LeuVal: 5.389 ± 0.635
0.299LeuTrp: 0.299 ± 0.469
2.695LeuTyr: 2.695 ± 0.293
0.0LeuXaa: 0.0 ± 0.0
Met
0.898MetAla: 0.898 ± 0.485
0.599MetCys: 0.599 ± 0.323
2.096MetAsp: 2.096 ± 1.626
0.599MetGlu: 0.599 ± 0.419
1.497MetPhe: 1.497 ± 1.392
1.796MetGly: 1.796 ± 1.971
0.299MetHis: 0.299 ± 0.162
3.293MetIle: 3.293 ± 0.967
2.695MetLys: 2.695 ± 0.786
2.994MetLeu: 2.994 ± 0.564
0.599MetMet: 0.599 ± 0.323
0.599MetAsn: 0.599 ± 0.323
0.898MetPro: 0.898 ± 0.313
0.0MetGln: 0.0 ± 0.0
1.198MetArg: 1.198 ± 0.351
2.096MetSer: 2.096 ± 0.448
1.198MetThr: 1.198 ± 0.34
2.096MetVal: 2.096 ± 0.448
0.0MetTrp: 0.0 ± 0.0
0.898MetTyr: 0.898 ± 0.313
0.0MetXaa: 0.0 ± 0.0
Asn
1.796AsnAla: 1.796 ± 0.804
1.796AsnCys: 1.796 ± 1.677
2.994AsnAsp: 2.994 ± 0.939
2.096AsnGlu: 2.096 ± 0.592
2.395AsnPhe: 2.395 ± 0.936
3.293AsnGly: 3.293 ± 0.35
1.497AsnHis: 1.497 ± 0.805
2.695AsnIle: 2.695 ± 0.563
4.491AsnLys: 4.491 ± 0.66
6.587AsnLeu: 6.587 ± 1.005
1.497AsnMet: 1.497 ± 0.724
1.198AsnAsn: 1.198 ± 0.34
2.695AsnPro: 2.695 ± 0.917
1.198AsnGln: 1.198 ± 1.29
2.395AsnArg: 2.395 ± 0.37
4.491AsnSer: 4.491 ± 1.474
2.096AsnThr: 2.096 ± 0.448
1.198AsnVal: 1.198 ± 0.647
0.299AsnTrp: 0.299 ± 0.162
1.796AsnTyr: 1.796 ± 0.804
0.0AsnXaa: 0.0 ± 0.0
Pro
0.299ProAla: 0.299 ± 0.469
0.599ProCys: 0.599 ± 0.419
3.293ProAsp: 3.293 ± 0.834
2.395ProGlu: 2.395 ± 0.37
2.395ProPhe: 2.395 ± 0.793
2.395ProGly: 2.395 ± 0.903
1.497ProHis: 1.497 ± 0.724
2.695ProIle: 2.695 ± 0.521
5.09ProLys: 5.09 ± 1.296
4.192ProLeu: 4.192 ± 1.271
0.898ProMet: 0.898 ± 0.402
0.898ProAsn: 0.898 ± 0.947
1.497ProPro: 1.497 ± 0.796
1.497ProGln: 1.497 ± 0.43
1.497ProArg: 1.497 ± 1.309
3.593ProSer: 3.593 ± 1.477
2.096ProThr: 2.096 ± 1.031
2.395ProVal: 2.395 ± 0.903
0.0ProTrp: 0.0 ± 0.0
0.898ProTyr: 0.898 ± 1.028
0.0ProXaa: 0.0 ± 0.0
Gln
1.198GlnAla: 1.198 ± 1.517
0.599GlnCys: 0.599 ± 0.323
1.198GlnAsp: 1.198 ± 0.34
1.796GlnGlu: 1.796 ± 0.682
1.497GlnPhe: 1.497 ± 1.185
1.497GlnGly: 1.497 ± 0.66
1.497GlnHis: 1.497 ± 0.795
1.497GlnIle: 1.497 ± 0.805
2.695GlnLys: 2.695 ± 0.993
4.79GlnLeu: 4.79 ± 0.893
1.497GlnMet: 1.497 ± 0.66
1.497GlnAsn: 1.497 ± 0.43
0.898GlnPro: 0.898 ± 1.414
0.599GlnGln: 0.599 ± 0.419
2.096GlnArg: 2.096 ± 0.76
1.796GlnSer: 1.796 ± 0.626
1.497GlnThr: 1.497 ± 1.185
0.599GlnVal: 0.599 ± 0.364
0.599GlnTrp: 0.599 ± 0.419
0.299GlnTyr: 0.299 ± 0.162
0.0GlnXaa: 0.0 ± 0.0
Arg
0.599ArgAla: 0.599 ± 0.937
2.096ArgCys: 2.096 ± 0.951
4.491ArgAsp: 4.491 ± 1.938
3.293ArgGlu: 3.293 ± 1.065
2.395ArgPhe: 2.395 ± 0.936
2.395ArgGly: 2.395 ± 0.342
0.898ArgHis: 0.898 ± 0.869
1.497ArgIle: 1.497 ± 0.539
3.593ArgLys: 3.593 ± 0.321
8.084ArgLeu: 8.084 ± 1.579
0.898ArgMet: 0.898 ± 0.485
3.293ArgAsn: 3.293 ± 2.273
2.395ArgPro: 2.395 ± 0.68
2.096ArgGln: 2.096 ± 0.235
2.695ArgArg: 2.695 ± 1.312
2.994ArgSer: 2.994 ± 0.958
1.796ArgThr: 1.796 ± 1.648
3.892ArgVal: 3.892 ± 0.913
0.299ArgTrp: 0.299 ± 0.492
1.198ArgTyr: 1.198 ± 0.647
0.0ArgXaa: 0.0 ± 0.0
Ser
2.994SerAla: 2.994 ± 0.912
1.497SerCys: 1.497 ± 0.761
5.988SerAsp: 5.988 ± 2.579
7.186SerGlu: 7.186 ± 1.145
5.09SerPhe: 5.09 ± 1.31
5.988SerGly: 5.988 ± 1.169
2.994SerHis: 2.994 ± 0.944
4.79SerIle: 4.79 ± 1.724
7.485SerLys: 7.485 ± 2.008
13.772SerLeu: 13.772 ± 0.604
1.198SerMet: 1.198 ± 0.34
2.395SerAsn: 2.395 ± 0.342
2.096SerPro: 2.096 ± 0.235
2.695SerGln: 2.695 ± 1.91
3.892SerArg: 3.892 ± 1.094
8.982SerSer: 8.982 ± 1.365
3.892SerThr: 3.892 ± 0.87
6.287SerVal: 6.287 ± 2.056
1.198SerTrp: 1.198 ± 0.34
2.994SerTyr: 2.994 ± 0.564
0.0SerXaa: 0.0 ± 0.0
Thr
1.796ThrAla: 1.796 ± 1.648
1.497ThrCys: 1.497 ± 0.22
2.395ThrAsp: 2.395 ± 0.966
2.994ThrGlu: 2.994 ± 0.677
0.898ThrPhe: 0.898 ± 0.5
2.695ThrGly: 2.695 ± 1.566
1.497ThrHis: 1.497 ± 1.314
2.395ThrIle: 2.395 ± 0.841
5.389ThrLys: 5.389 ± 1.45
5.09ThrLeu: 5.09 ± 1.566
2.096ThrMet: 2.096 ± 0.694
1.198ThrAsn: 1.198 ± 0.447
2.994ThrPro: 2.994 ± 1.734
1.198ThrGln: 1.198 ± 0.729
3.293ThrArg: 3.293 ± 1.141
4.491ThrSer: 4.491 ± 0.599
1.497ThrThr: 1.497 ± 0.43
4.192ThrVal: 4.192 ± 0.647
0.898ThrTrp: 0.898 ± 0.313
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.096ValAla: 2.096 ± 0.793
0.299ValCys: 0.299 ± 0.162
3.892ValAsp: 3.892 ± 0.971
4.192ValGlu: 4.192 ± 1.779
2.096ValPhe: 2.096 ± 0.835
3.593ValGly: 3.593 ± 0.585
0.599ValHis: 0.599 ± 0.419
5.988ValIle: 5.988 ± 1.302
4.491ValLys: 4.491 ± 1.796
5.689ValLeu: 5.689 ± 2.141
1.497ValMet: 1.497 ± 0.808
2.695ValAsn: 2.695 ± 0.993
2.695ValPro: 2.695 ± 0.993
2.096ValGln: 2.096 ± 1.019
4.491ValArg: 4.491 ± 0.599
7.485ValSer: 7.485 ± 0.673
2.395ValThr: 2.395 ± 1.261
2.994ValVal: 2.994 ± 0.939
1.198ValTrp: 1.198 ± 0.729
0.299ValTyr: 0.299 ± 0.469
0.0ValXaa: 0.0 ± 0.0
Trp
0.599TrpAla: 0.599 ± 0.419
0.299TrpCys: 0.299 ± 0.162
0.898TrpAsp: 0.898 ± 1.406
0.299TrpGlu: 0.299 ± 0.162
0.599TrpPhe: 0.599 ± 0.323
0.599TrpGly: 0.599 ± 0.323
0.299TrpHis: 0.299 ± 0.162
0.599TrpIle: 0.599 ± 0.323
0.599TrpLys: 0.599 ± 0.747
1.796TrpLeu: 1.796 ± 0.682
0.299TrpMet: 0.299 ± 0.469
0.0TrpAsn: 0.0 ± 0.0
0.898TrpPro: 0.898 ± 0.313
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.299TrpSer: 0.299 ± 0.492
0.0TrpThr: 0.0 ± 0.0
1.198TrpVal: 1.198 ± 0.647
0.0TrpTrp: 0.0 ± 0.0
0.299TrpTyr: 0.299 ± 0.492
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.299TyrAla: 0.299 ± 0.162
0.898TyrCys: 0.898 ± 0.5
1.198TyrAsp: 1.198 ± 0.721
2.695TyrGlu: 2.695 ± 0.293
0.898TyrPhe: 0.898 ± 0.485
0.898TyrGly: 0.898 ± 0.485
0.898TyrHis: 0.898 ± 0.485
2.096TyrIle: 2.096 ± 0.694
2.395TyrLys: 2.395 ± 0.702
2.395TyrLeu: 2.395 ± 1.339
0.299TyrMet: 0.299 ± 0.492
2.096TyrAsn: 2.096 ± 0.235
0.599TyrPro: 0.599 ± 0.323
0.898TyrGln: 0.898 ± 0.313
2.395TyrArg: 2.395 ± 0.936
1.497TyrSer: 1.497 ± 0.808
2.096TyrThr: 2.096 ± 0.235
1.497TyrVal: 1.497 ± 0.22
0.0TyrTrp: 0.0 ± 0.0
0.599TyrTyr: 0.599 ± 0.323
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3341 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski