Amino acid dipepetide frequency for Hubei picorna-like virus 36

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.01AlaAla: 5.01 ± 0.0
0.668AlaCys: 0.668 ± 0.0
3.34AlaAsp: 3.34 ± 0.0
5.01AlaGlu: 5.01 ± 0.0
3.006AlaPhe: 3.006 ± 0.0
4.342AlaGly: 4.342 ± 0.0
1.67AlaHis: 1.67 ± 0.0
5.344AlaIle: 5.344 ± 0.0
4.342AlaLys: 4.342 ± 0.0
3.674AlaLeu: 3.674 ± 0.0
1.002AlaMet: 1.002 ± 0.0
4.676AlaAsn: 4.676 ± 0.0
3.006AlaPro: 3.006 ± 0.0
2.672AlaGln: 2.672 ± 0.0
4.342AlaArg: 4.342 ± 0.0
4.008AlaSer: 4.008 ± 0.0
5.01AlaThr: 5.01 ± 0.0
4.008AlaVal: 4.008 ± 0.0
1.002AlaTrp: 1.002 ± 0.0
0.668AlaTyr: 0.668 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.67CysAla: 1.67 ± 0.0
0.334CysCys: 0.334 ± 0.0
1.002CysAsp: 1.002 ± 0.0
0.334CysGlu: 0.334 ± 0.0
1.336CysPhe: 1.336 ± 0.0
2.338CysGly: 2.338 ± 0.0
0.334CysHis: 0.334 ± 0.0
0.668CysIle: 0.668 ± 0.0
0.334CysLys: 0.334 ± 0.0
1.336CysLeu: 1.336 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.002CysAsn: 1.002 ± 0.0
0.334CysPro: 0.334 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.334CysArg: 0.334 ± 0.0
1.336CysSer: 1.336 ± 0.0
0.668CysThr: 0.668 ± 0.0
1.002CysVal: 1.002 ± 0.0
0.334CysTrp: 0.334 ± 0.0
0.334CysTyr: 0.334 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.674AspAla: 3.674 ± 0.0
0.668AspCys: 0.668 ± 0.0
3.006AspAsp: 3.006 ± 0.0
2.672AspGlu: 2.672 ± 0.0
4.342AspPhe: 4.342 ± 0.0
3.34AspGly: 3.34 ± 0.0
2.338AspHis: 2.338 ± 0.0
5.01AspIle: 5.01 ± 0.0
3.674AspLys: 3.674 ± 0.0
3.674AspLeu: 3.674 ± 0.0
1.67AspMet: 1.67 ± 0.0
1.336AspAsn: 1.336 ± 0.0
3.34AspPro: 3.34 ± 0.0
1.336AspGln: 1.336 ± 0.0
2.338AspArg: 2.338 ± 0.0
3.006AspSer: 3.006 ± 0.0
3.34AspThr: 3.34 ± 0.0
4.342AspVal: 4.342 ± 0.0
1.336AspTrp: 1.336 ± 0.0
3.006AspTyr: 3.006 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.004GluAla: 2.004 ± 0.0
0.668GluCys: 0.668 ± 0.0
2.672GluAsp: 2.672 ± 0.0
2.004GluGlu: 2.004 ± 0.0
2.672GluPhe: 2.672 ± 0.0
2.004GluGly: 2.004 ± 0.0
1.002GluHis: 1.002 ± 0.0
3.006GluIle: 3.006 ± 0.0
4.676GluLys: 4.676 ± 0.0
5.01GluLeu: 5.01 ± 0.0
3.006GluMet: 3.006 ± 0.0
2.004GluAsn: 2.004 ± 0.0
1.67GluPro: 1.67 ± 0.0
1.336GluGln: 1.336 ± 0.0
1.67GluArg: 1.67 ± 0.0
3.674GluSer: 3.674 ± 0.0
4.008GluThr: 4.008 ± 0.0
4.676GluVal: 4.676 ± 0.0
0.334GluTrp: 0.334 ± 0.0
2.338GluTyr: 2.338 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.336PheAla: 1.336 ± 0.0
0.334PheCys: 0.334 ± 0.0
3.674PheAsp: 3.674 ± 0.0
2.338PheGlu: 2.338 ± 0.0
1.336PhePhe: 1.336 ± 0.0
4.342PheGly: 4.342 ± 0.0
0.668PheHis: 0.668 ± 0.0
1.67PheIle: 1.67 ± 0.0
2.338PheLys: 2.338 ± 0.0
3.34PheLeu: 3.34 ± 0.0
1.002PheMet: 1.002 ± 0.0
1.67PheAsn: 1.67 ± 0.0
2.004PhePro: 2.004 ± 0.0
2.004PheGln: 2.004 ± 0.0
1.002PheArg: 1.002 ± 0.0
5.01PheSer: 5.01 ± 0.0
3.674PheThr: 3.674 ± 0.0
3.006PheVal: 3.006 ± 0.0
0.668PheTrp: 0.668 ± 0.0
2.338PheTyr: 2.338 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.344GlyAla: 5.344 ± 0.0
0.334GlyCys: 0.334 ± 0.0
3.006GlyAsp: 3.006 ± 0.0
2.672GlyGlu: 2.672 ± 0.0
2.004GlyPhe: 2.004 ± 0.0
4.008GlyGly: 4.008 ± 0.0
1.67GlyHis: 1.67 ± 0.0
4.676GlyIle: 4.676 ± 0.0
4.342GlyLys: 4.342 ± 0.0
5.678GlyLeu: 5.678 ± 0.0
1.67GlyMet: 1.67 ± 0.0
2.338GlyAsn: 2.338 ± 0.0
3.674GlyPro: 3.674 ± 0.0
1.67GlyGln: 1.67 ± 0.0
2.338GlyArg: 2.338 ± 0.0
4.676GlySer: 4.676 ± 0.0
4.342GlyThr: 4.342 ± 0.0
4.676GlyVal: 4.676 ± 0.0
0.668GlyTrp: 0.668 ± 0.0
2.338GlyTyr: 2.338 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.668HisAla: 0.668 ± 0.0
0.334HisCys: 0.334 ± 0.0
0.668HisAsp: 0.668 ± 0.0
1.002HisGlu: 1.002 ± 0.0
0.668HisPhe: 0.668 ± 0.0
2.004HisGly: 2.004 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.336HisIle: 1.336 ± 0.0
1.002HisLys: 1.002 ± 0.0
2.004HisLeu: 2.004 ± 0.0
0.668HisMet: 0.668 ± 0.0
1.336HisAsn: 1.336 ± 0.0
1.002HisPro: 1.002 ± 0.0
2.004HisGln: 2.004 ± 0.0
0.668HisArg: 0.668 ± 0.0
1.336HisSer: 1.336 ± 0.0
1.67HisThr: 1.67 ± 0.0
1.336HisVal: 1.336 ± 0.0
0.334HisTrp: 0.334 ± 0.0
1.67HisTyr: 1.67 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.34IleAla: 3.34 ± 0.0
2.004IleCys: 2.004 ± 0.0
3.674IleAsp: 3.674 ± 0.0
2.672IleGlu: 2.672 ± 0.0
2.672IlePhe: 2.672 ± 0.0
5.01IleGly: 5.01 ± 0.0
1.336IleHis: 1.336 ± 0.0
1.67IleIle: 1.67 ± 0.0
2.672IleLys: 2.672 ± 0.0
6.68IleLeu: 6.68 ± 0.0
1.336IleMet: 1.336 ± 0.0
3.006IleAsn: 3.006 ± 0.0
3.674IlePro: 3.674 ± 0.0
1.67IleGln: 1.67 ± 0.0
4.342IleArg: 4.342 ± 0.0
3.674IleSer: 3.674 ± 0.0
3.674IleThr: 3.674 ± 0.0
5.01IleVal: 5.01 ± 0.0
0.0IleTrp: 0.0 ± 0.0
3.006IleTyr: 3.006 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.01LysAla: 5.01 ± 0.0
0.668LysCys: 0.668 ± 0.0
2.672LysAsp: 2.672 ± 0.0
3.34LysGlu: 3.34 ± 0.0
1.002LysPhe: 1.002 ± 0.0
3.34LysGly: 3.34 ± 0.0
1.67LysHis: 1.67 ± 0.0
5.344LysIle: 5.344 ± 0.0
4.008LysLys: 4.008 ± 0.0
3.674LysLeu: 3.674 ± 0.0
2.338LysMet: 2.338 ± 0.0
2.004LysAsn: 2.004 ± 0.0
1.336LysPro: 1.336 ± 0.0
2.338LysGln: 2.338 ± 0.0
2.338LysArg: 2.338 ± 0.0
3.006LysSer: 3.006 ± 0.0
5.01LysThr: 5.01 ± 0.0
4.342LysVal: 4.342 ± 0.0
1.336LysTrp: 1.336 ± 0.0
2.338LysTyr: 2.338 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.676LeuAla: 4.676 ± 0.0
1.67LeuCys: 1.67 ± 0.0
3.674LeuAsp: 3.674 ± 0.0
3.006LeuGlu: 3.006 ± 0.0
4.342LeuPhe: 4.342 ± 0.0
5.678LeuGly: 5.678 ± 0.0
2.004LeuHis: 2.004 ± 0.0
4.676LeuIle: 4.676 ± 0.0
4.008LeuLys: 4.008 ± 0.0
7.682LeuLeu: 7.682 ± 0.0
1.67LeuMet: 1.67 ± 0.0
2.672LeuAsn: 2.672 ± 0.0
5.01LeuPro: 5.01 ± 0.0
3.006LeuGln: 3.006 ± 0.0
4.342LeuArg: 4.342 ± 0.0
9.018LeuSer: 9.018 ± 0.0
7.014LeuThr: 7.014 ± 0.0
7.348LeuVal: 7.348 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
3.006LeuTyr: 3.006 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.006MetAla: 3.006 ± 0.0
0.668MetCys: 0.668 ± 0.0
3.34MetAsp: 3.34 ± 0.0
1.67MetGlu: 1.67 ± 0.0
1.002MetPhe: 1.002 ± 0.0
1.336MetGly: 1.336 ± 0.0
0.668MetHis: 0.668 ± 0.0
0.334MetIle: 0.334 ± 0.0
0.668MetLys: 0.668 ± 0.0
1.002MetLeu: 1.002 ± 0.0
0.668MetMet: 0.668 ± 0.0
1.336MetAsn: 1.336 ± 0.0
1.002MetPro: 1.002 ± 0.0
0.668MetGln: 0.668 ± 0.0
1.002MetArg: 1.002 ± 0.0
3.34MetSer: 3.34 ± 0.0
1.67MetThr: 1.67 ± 0.0
2.672MetVal: 2.672 ± 0.0
0.334MetTrp: 0.334 ± 0.0
1.002MetTyr: 1.002 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.008AsnAla: 4.008 ± 0.0
0.668AsnCys: 0.668 ± 0.0
2.338AsnAsp: 2.338 ± 0.0
2.004AsnGlu: 2.004 ± 0.0
1.336AsnPhe: 1.336 ± 0.0
3.006AsnGly: 3.006 ± 0.0
0.334AsnHis: 0.334 ± 0.0
2.338AsnIle: 2.338 ± 0.0
2.338AsnLys: 2.338 ± 0.0
3.34AsnLeu: 3.34 ± 0.0
1.336AsnMet: 1.336 ± 0.0
3.006AsnAsn: 3.006 ± 0.0
3.674AsnPro: 3.674 ± 0.0
1.002AsnGln: 1.002 ± 0.0
2.672AsnArg: 2.672 ± 0.0
1.336AsnSer: 1.336 ± 0.0
2.672AsnThr: 2.672 ± 0.0
3.34AsnVal: 3.34 ± 0.0
1.67AsnTrp: 1.67 ± 0.0
3.674AsnTyr: 3.674 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.006ProAla: 3.006 ± 0.0
0.668ProCys: 0.668 ± 0.0
3.34ProAsp: 3.34 ± 0.0
1.67ProGlu: 1.67 ± 0.0
3.006ProPhe: 3.006 ± 0.0
2.004ProGly: 2.004 ± 0.0
1.002ProHis: 1.002 ± 0.0
3.006ProIle: 3.006 ± 0.0
3.006ProLys: 3.006 ± 0.0
5.344ProLeu: 5.344 ± 0.0
1.002ProMet: 1.002 ± 0.0
1.002ProAsn: 1.002 ± 0.0
2.672ProPro: 2.672 ± 0.0
1.002ProGln: 1.002 ± 0.0
1.002ProArg: 1.002 ± 0.0
4.008ProSer: 4.008 ± 0.0
4.676ProThr: 4.676 ± 0.0
4.676ProVal: 4.676 ± 0.0
0.0ProTrp: 0.0 ± 0.0
2.004ProTyr: 2.004 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.008GlnAla: 4.008 ± 0.0
0.334GlnCys: 0.334 ± 0.0
2.672GlnAsp: 2.672 ± 0.0
1.336GlnGlu: 1.336 ± 0.0
3.006GlnPhe: 3.006 ± 0.0
2.004GlnGly: 2.004 ± 0.0
1.336GlnHis: 1.336 ± 0.0
3.006GlnIle: 3.006 ± 0.0
1.67GlnLys: 1.67 ± 0.0
3.674GlnLeu: 3.674 ± 0.0
2.004GlnMet: 2.004 ± 0.0
1.002GlnAsn: 1.002 ± 0.0
1.67GlnPro: 1.67 ± 0.0
1.336GlnGln: 1.336 ± 0.0
1.002GlnArg: 1.002 ± 0.0
2.672GlnSer: 2.672 ± 0.0
2.338GlnThr: 2.338 ± 0.0
2.338GlnVal: 2.338 ± 0.0
1.002GlnTrp: 1.002 ± 0.0
0.334GlnTyr: 0.334 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.338ArgAla: 2.338 ± 0.0
1.002ArgCys: 1.002 ± 0.0
2.338ArgAsp: 2.338 ± 0.0
3.674ArgGlu: 3.674 ± 0.0
1.336ArgPhe: 1.336 ± 0.0
1.67ArgGly: 1.67 ± 0.0
0.0ArgHis: 0.0 ± 0.0
3.674ArgIle: 3.674 ± 0.0
3.006ArgLys: 3.006 ± 0.0
3.006ArgLeu: 3.006 ± 0.0
2.338ArgMet: 2.338 ± 0.0
1.002ArgAsn: 1.002 ± 0.0
2.672ArgPro: 2.672 ± 0.0
3.006ArgGln: 3.006 ± 0.0
4.008ArgArg: 4.008 ± 0.0
1.67ArgSer: 1.67 ± 0.0
1.67ArgThr: 1.67 ± 0.0
1.336ArgVal: 1.336 ± 0.0
1.002ArgTrp: 1.002 ± 0.0
3.34ArgTyr: 3.34 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.678SerAla: 5.678 ± 0.0
1.002SerCys: 1.002 ± 0.0
3.674SerAsp: 3.674 ± 0.0
2.338SerGlu: 2.338 ± 0.0
5.01SerPhe: 5.01 ± 0.0
4.008SerGly: 4.008 ± 0.0
1.67SerHis: 1.67 ± 0.0
4.342SerIle: 4.342 ± 0.0
3.34SerLys: 3.34 ± 0.0
6.68SerLeu: 6.68 ± 0.0
1.002SerMet: 1.002 ± 0.0
3.674SerAsn: 3.674 ± 0.0
3.006SerPro: 3.006 ± 0.0
2.004SerGln: 2.004 ± 0.0
1.336SerArg: 1.336 ± 0.0
7.348SerSer: 7.348 ± 0.0
6.346SerThr: 6.346 ± 0.0
5.678SerVal: 5.678 ± 0.0
0.668SerTrp: 0.668 ± 0.0
3.006SerTyr: 3.006 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.342ThrAla: 4.342 ± 0.0
1.002ThrCys: 1.002 ± 0.0
3.34ThrAsp: 3.34 ± 0.0
5.678ThrGlu: 5.678 ± 0.0
2.338ThrPhe: 2.338 ± 0.0
5.01ThrGly: 5.01 ± 0.0
1.336ThrHis: 1.336 ± 0.0
3.674ThrIle: 3.674 ± 0.0
4.676ThrLys: 4.676 ± 0.0
7.014ThrLeu: 7.014 ± 0.0
2.338ThrMet: 2.338 ± 0.0
3.34ThrAsn: 3.34 ± 0.0
2.338ThrPro: 2.338 ± 0.0
6.012ThrGln: 6.012 ± 0.0
2.004ThrArg: 2.004 ± 0.0
4.008ThrSer: 4.008 ± 0.0
6.68ThrThr: 6.68 ± 0.0
5.678ThrVal: 5.678 ± 0.0
1.336ThrTrp: 1.336 ± 0.0
1.67ThrTyr: 1.67 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.342ValAla: 4.342 ± 0.0
0.668ValCys: 0.668 ± 0.0
5.01ValAsp: 5.01 ± 0.0
3.674ValGlu: 3.674 ± 0.0
2.338ValPhe: 2.338 ± 0.0
1.67ValGly: 1.67 ± 0.0
1.67ValHis: 1.67 ± 0.0
4.008ValIle: 4.008 ± 0.0
5.01ValLys: 5.01 ± 0.0
8.35ValLeu: 8.35 ± 0.0
1.002ValMet: 1.002 ± 0.0
6.68ValAsn: 6.68 ± 0.0
4.342ValPro: 4.342 ± 0.0
3.006ValGln: 3.006 ± 0.0
4.008ValArg: 4.008 ± 0.0
3.34ValSer: 3.34 ± 0.0
6.346ValThr: 6.346 ± 0.0
6.346ValVal: 6.346 ± 0.0
0.668ValTrp: 0.668 ± 0.0
3.006ValTyr: 3.006 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.336TrpAla: 1.336 ± 0.0
0.334TrpCys: 0.334 ± 0.0
0.668TrpAsp: 0.668 ± 0.0
0.334TrpGlu: 0.334 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.336TrpGly: 1.336 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.002TrpIle: 1.002 ± 0.0
0.668TrpLys: 0.668 ± 0.0
1.002TrpLeu: 1.002 ± 0.0
0.668TrpMet: 0.668 ± 0.0
0.334TrpAsn: 0.334 ± 0.0
0.334TrpPro: 0.334 ± 0.0
1.336TrpGln: 1.336 ± 0.0
0.668TrpArg: 0.668 ± 0.0
1.002TrpSer: 1.002 ± 0.0
0.334TrpThr: 0.334 ± 0.0
1.336TrpVal: 1.336 ± 0.0
0.334TrpTrp: 0.334 ± 0.0
0.668TrpTyr: 0.668 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.004TyrAla: 2.004 ± 0.0
1.002TyrCys: 1.002 ± 0.0
3.34TyrAsp: 3.34 ± 0.0
3.006TyrGlu: 3.006 ± 0.0
1.002TyrPhe: 1.002 ± 0.0
3.674TyrGly: 3.674 ± 0.0
1.002TyrHis: 1.002 ± 0.0
2.338TyrIle: 2.338 ± 0.0
1.336TyrLys: 1.336 ± 0.0
2.672TyrLeu: 2.672 ± 0.0
0.334TyrMet: 0.334 ± 0.0
2.672TyrAsn: 2.672 ± 0.0
1.336TyrPro: 1.336 ± 0.0
1.336TyrGln: 1.336 ± 0.0
2.672TyrArg: 2.672 ± 0.0
4.342TyrSer: 4.342 ± 0.0
2.672TyrThr: 2.672 ± 0.0
2.338TyrVal: 2.338 ± 0.0
0.668TyrTrp: 0.668 ± 0.0
1.002TyrTyr: 1.002 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2995 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski