Amino acid dipepetide frequency for Alternaria alternata (Alternaria rot fungus) (Torula alternata)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.647AlaAla: 8.647 ± 0.051	1.128AlaCys: 1.128 ± 0.015	4.267AlaAsp: 4.267 ± 0.031	5.065AlaGlu: 5.065 ± 0.036	3.206AlaPhe: 3.206 ± 0.028	5.642AlaGly: 5.642 ± 0.034	1.857AlaHis: 1.857 ± 0.018	4.339AlaIle: 4.339 ± 0.031	4.336AlaLys: 4.336 ± 0.035	7.493AlaLeu: 7.493 ± 0.044	2.089AlaMet: 2.089 ± 0.022	3.124AlaAsn: 3.124 ± 0.023	5.035AlaPro: 5.035 ± 0.04	3.558AlaGln: 3.558 ± 0.031	4.821AlaArg: 4.821 ± 0.03	7.287AlaSer: 7.287 ± 0.038	5.469AlaThr: 5.469 ± 0.032	5.226AlaVal: 5.226 ± 0.036	1.205AlaTrp: 1.205 ± 0.015	2.342AlaTyr: 2.342 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	1.006CysAla: 1.006 ± 0.013	0.289CysCys: 0.289 ± 0.008	0.716CysAsp: 0.716 ± 0.013	0.643CysGlu: 0.643 ± 0.011	0.544CysPhe: 0.544 ± 0.01	0.992CysGly: 0.992 ± 0.015	0.326CysHis: 0.326 ± 0.008	0.761CysIle: 0.761 ± 0.012	0.562CysLys: 0.562 ± 0.011	1.225CysLeu: 1.225 ± 0.014	0.306CysMet: 0.306 ± 0.007	0.487CysAsn: 0.487 ± 0.009	0.665CysPro: 0.665 ± 0.012	0.461CysGln: 0.461 ± 0.009	0.758CysArg: 0.758 ± 0.013	0.946CysSer: 0.946 ± 0.016	0.779CysThr: 0.779 ± 0.013	0.831CysVal: 0.831 ± 0.013	0.221CysTrp: 0.221 ± 0.006	0.378CysTyr: 0.378 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.033AspAla: 5.033 ± 0.037	0.659AspCys: 0.659 ± 0.011	4.361AspAsp: 4.361 ± 0.041	4.442AspGlu: 4.442 ± 0.036	2.255AspPhe: 2.255 ± 0.022	3.96AspGly: 3.96 ± 0.033	1.257AspHis: 1.257 ± 0.018	3.062AspIle: 3.062 ± 0.024	2.519AspLys: 2.519 ± 0.023	4.842AspLeu: 4.842 ± 0.028	1.416AspMet: 1.416 ± 0.014	1.93AspAsn: 1.93 ± 0.019	3.187AspPro: 3.187 ± 0.022	1.894AspGln: 1.894 ± 0.017	3.014AspArg: 3.014 ± 0.027	3.946AspSer: 3.946 ± 0.027	3.172AspThr: 3.172 ± 0.024	3.872AspVal: 3.872 ± 0.027	0.954AspTrp: 0.954 ± 0.013	1.686AspTyr: 1.686 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.364GluAla: 5.364 ± 0.038	0.66GluCys: 0.66 ± 0.011	4.353GluAsp: 4.353 ± 0.034	5.437GluGlu: 5.437 ± 0.053	1.868GluPhe: 1.868 ± 0.021	3.804GluGly: 3.804 ± 0.028	1.505GluHis: 1.505 ± 0.017	2.907GluIle: 2.907 ± 0.022	3.839GluLys: 3.839 ± 0.029	5.058GluLeu: 5.058 ± 0.033	1.493GluMet: 1.493 ± 0.02	2.201GluAsn: 2.201 ± 0.018	2.759GluPro: 2.759 ± 0.026	2.661GluGln: 2.661 ± 0.024	3.966GluArg: 3.966 ± 0.033	4.057GluSer: 4.057 ± 0.031	3.376GluThr: 3.376 ± 0.025	3.528GluVal: 3.528 ± 0.029	0.939GluTrp: 0.939 ± 0.012	1.729GluTyr: 1.729 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.204PheAla: 3.204 ± 0.026	0.556PheCys: 0.556 ± 0.01	2.327PheAsp: 2.327 ± 0.021	2.15PheGlu: 2.15 ± 0.02	1.615PhePhe: 1.615 ± 0.018	2.887PheGly: 2.887 ± 0.024	0.867PheHis: 0.867 ± 0.012	1.733PheIle: 1.733 ± 0.022	1.571PheLys: 1.571 ± 0.015	3.308PheLeu: 3.308 ± 0.028	0.795PheMet: 0.795 ± 0.013	1.46PheAsn: 1.46 ± 0.017	1.904PhePro: 1.904 ± 0.021	1.378PheGln: 1.378 ± 0.016	1.924PheArg: 1.924 ± 0.018	2.922PheSer: 2.922 ± 0.026	2.215PheThr: 2.215 ± 0.02	2.419PheVal: 2.419 ± 0.023	0.661PheTrp: 0.661 ± 0.011	1.095PheTyr: 1.095 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.267GlyAla: 5.267 ± 0.033	0.91GlyCys: 0.91 ± 0.014	3.591GlyAsp: 3.591 ± 0.026	3.613GlyGlu: 3.613 ± 0.029	2.794GlyPhe: 2.794 ± 0.027	5.713GlyGly: 5.713 ± 0.056	1.624GlyHis: 1.624 ± 0.019	3.454GlyIle: 3.454 ± 0.028	3.592GlyLys: 3.592 ± 0.03	5.75GlyLeu: 5.75 ± 0.032	1.732GlyMet: 1.732 ± 0.021	2.587GlyAsn: 2.587 ± 0.025	3.12GlyPro: 3.12 ± 0.028	2.508GlyGln: 2.508 ± 0.022	3.987GlyArg: 3.987 ± 0.031	5.452GlySer: 5.452 ± 0.037	4.008GlyThr: 4.008 ± 0.026	4.314GlyVal: 4.314 ± 0.036	1.207GlyTrp: 1.207 ± 0.015	2.21GlyTyr: 2.21 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.938HisAla: 1.938 ± 0.019	0.367HisCys: 0.367 ± 0.008	1.404HisAsp: 1.404 ± 0.018	1.4HisGlu: 1.4 ± 0.016	0.937HisPhe: 0.937 ± 0.013	1.692HisGly: 1.692 ± 0.018	0.85HisHis: 0.85 ± 0.014	1.253HisIle: 1.253 ± 0.017	0.979HisLys: 0.979 ± 0.014	2.182HisLeu: 2.182 ± 0.02	0.558HisMet: 0.558 ± 0.01	0.887HisAsn: 0.887 ± 0.011	1.609HisPro: 1.609 ± 0.016	1.014HisGln: 1.014 ± 0.014	1.494HisArg: 1.494 ± 0.018	1.808HisSer: 1.808 ± 0.019	1.415HisThr: 1.415 ± 0.016	1.521HisVal: 1.521 ± 0.017	0.367HisTrp: 0.367 ± 0.008	0.738HisTyr: 0.738 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.431IleAla: 4.431 ± 0.032	0.759IleCys: 0.759 ± 0.013	2.912IleAsp: 2.912 ± 0.02	2.926IleGlu: 2.926 ± 0.023	1.926IlePhe: 1.926 ± 0.022	3.199IleGly: 3.199 ± 0.029	1.188IleHis: 1.188 ± 0.016	2.432IleIle: 2.432 ± 0.026	2.234IleLys: 2.234 ± 0.019	4.33IleLeu: 4.33 ± 0.032	1.071IleMet: 1.071 ± 0.014	1.774IleAsn: 1.774 ± 0.016	3.002IlePro: 3.002 ± 0.021	1.868IleGln: 1.868 ± 0.019	2.733IleArg: 2.733 ± 0.022	3.694IleSer: 3.694 ± 0.026	3.012IleThr: 3.012 ± 0.026	3.246IleVal: 3.246 ± 0.026	0.769IleTrp: 0.769 ± 0.013	1.441IleTyr: 1.441 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.425LysAla: 4.425 ± 0.034	0.533LysCys: 0.533 ± 0.01	3.054LysAsp: 3.054 ± 0.026	3.644LysGlu: 3.644 ± 0.034	1.471LysPhe: 1.471 ± 0.017	3.085LysGly: 3.085 ± 0.027	1.241LysHis: 1.241 ± 0.016	2.326LysIle: 2.326 ± 0.02	3.666LysLys: 3.666 ± 0.042	4.085LysLeu: 4.085 ± 0.027	1.093LysMet: 1.093 ± 0.015	1.843LysAsn: 1.843 ± 0.021	2.835LysPro: 2.835 ± 0.026	1.985LysGln: 1.985 ± 0.022	3.555LysArg: 3.555 ± 0.027	3.542LysSer: 3.542 ± 0.031	3.041LysThr: 3.041 ± 0.025	2.835LysVal: 2.835 ± 0.025	0.714LysTrp: 0.714 ± 0.012	1.408LysTyr: 1.408 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.453LeuAla: 7.453 ± 0.036	1.228LeuCys: 1.228 ± 0.015	4.996LeuAsp: 4.996 ± 0.03	5.3LeuGlu: 5.3 ± 0.031	3.195LeuPhe: 3.195 ± 0.026	5.602LeuGly: 5.602 ± 0.036	2.235LeuHis: 2.235 ± 0.021	3.768LeuIle: 3.768 ± 0.028	4.175LeuLys: 4.175 ± 0.029	7.872LeuLeu: 7.872 ± 0.055	1.759LeuMet: 1.759 ± 0.018	3.136LeuAsn: 3.136 ± 0.023	5.419LeuPro: 5.419 ± 0.033	3.766LeuGln: 3.766 ± 0.027	5.503LeuArg: 5.503 ± 0.036	6.917LeuSer: 6.917 ± 0.037	4.724LeuThr: 4.724 ± 0.032	5.221LeuVal: 5.221 ± 0.039	1.214LeuTrp: 1.214 ± 0.017	2.376LeuTyr: 2.376 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.2MetAla: 2.2 ± 0.019	0.277MetCys: 0.277 ± 0.006	1.318MetAsp: 1.318 ± 0.013	1.319MetGlu: 1.319 ± 0.014	0.821MetPhe: 0.821 ± 0.013	1.529MetGly: 1.529 ± 0.018	0.536MetHis: 0.536 ± 0.01	1.027MetIle: 1.027 ± 0.013	1.095MetLys: 1.095 ± 0.014	1.957MetLeu: 1.957 ± 0.019	0.648MetMet: 0.648 ± 0.011	0.873MetAsn: 0.873 ± 0.012	1.369MetPro: 1.369 ± 0.017	0.955MetGln: 0.955 ± 0.015	1.379MetArg: 1.379 ± 0.016	2.023MetSer: 2.023 ± 0.02	1.356MetThr: 1.356 ± 0.015	1.335MetVal: 1.335 ± 0.014	0.303MetTrp: 0.303 ± 0.007	0.612MetTyr: 0.612 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.356AsnAla: 3.356 ± 0.023	0.445AsnCys: 0.445 ± 0.009	2.08AsnAsp: 2.08 ± 0.019	2.115AsnGlu: 2.115 ± 0.02	1.43AsnPhe: 1.43 ± 0.014	3.093AsnGly: 3.093 ± 0.03	0.866AsnHis: 0.866 ± 0.013	2.071AsnIle: 2.071 ± 0.019	1.696AsnLys: 1.696 ± 0.018	3.189AsnLeu: 3.189 ± 0.022	0.923AsnMet: 0.923 ± 0.014	1.596AsnAsn: 1.596 ± 0.02	2.345AsnPro: 2.345 ± 0.021	1.362AsnGln: 1.362 ± 0.013	1.898AsnArg: 1.898 ± 0.02	2.722AsnSer: 2.722 ± 0.022	2.379AsnThr: 2.379 ± 0.02	2.438AsnVal: 2.438 ± 0.02	0.587AsnTrp: 0.587 ± 0.009	1.112AsnTyr: 1.112 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	5.156ProAla: 5.156 ± 0.039	0.526ProCys: 0.526 ± 0.01	3.087ProAsp: 3.087 ± 0.021	3.707ProGlu: 3.707 ± 0.03	2.031ProPhe: 2.031 ± 0.021	3.69ProGly: 3.69 ± 0.03	1.363ProHis: 1.363 ± 0.014	2.597ProIle: 2.597 ± 0.024	2.815ProLys: 2.815 ± 0.026	4.518ProLeu: 4.518 ± 0.03	1.17ProMet: 1.17 ± 0.017	2.32ProAsn: 2.32 ± 0.021	4.953ProPro: 4.953 ± 0.076	2.564ProGln: 2.564 ± 0.032	3.293ProArg: 3.293 ± 0.027	5.82ProSer: 5.82 ± 0.039	4.237ProThr: 4.237 ± 0.035	3.477ProVal: 3.477 ± 0.029	0.747ProTrp: 0.747 ± 0.011	1.608ProTyr: 1.608 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.477GlnAla: 3.477 ± 0.026	0.5GlnCys: 0.5 ± 0.009	2.223GlnAsp: 2.223 ± 0.021	2.502GlnGlu: 2.502 ± 0.022	1.271GlnPhe: 1.271 ± 0.015	2.421GlnGly: 2.421 ± 0.023	1.208GlnHis: 1.208 ± 0.015	1.865GlnIle: 1.865 ± 0.02	2.035GlnLys: 2.035 ± 0.022	3.387GlnLeu: 3.387 ± 0.025	0.907GlnMet: 0.907 ± 0.013	1.62GlnAsn: 1.62 ± 0.016	2.568GlnPro: 2.568 ± 0.027	2.627GlnGln: 2.627 ± 0.042	2.722GlnArg: 2.722 ± 0.023	3.15GlnSer: 3.15 ± 0.026	2.353GlnThr: 2.353 ± 0.02	2.118GlnVal: 2.118 ± 0.017	0.609GlnTrp: 0.609 ± 0.01	1.289GlnTyr: 1.289 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.543ArgAla: 4.543 ± 0.033	0.761ArgCys: 0.761 ± 0.013	3.265ArgAsp: 3.265 ± 0.027	3.627ArgGlu: 3.627 ± 0.035	2.063ArgPhe: 2.063 ± 0.022	3.572ArgGly: 3.572 ± 0.031	1.554ArgHis: 1.554 ± 0.017	2.978ArgIle: 2.978 ± 0.023	3.561ArgLys: 3.561 ± 0.029	5.219ArgLeu: 5.219 ± 0.029	1.41ArgMet: 1.41 ± 0.016	2.366ArgAsn: 2.366 ± 0.021	3.428ArgPro: 3.428 ± 0.029	2.616ArgGln: 2.616 ± 0.024	4.833ArgArg: 4.833 ± 0.043	4.773ArgSer: 4.773 ± 0.039	3.417ArgThr: 3.417 ± 0.025	3.204ArgVal: 3.204 ± 0.024	0.957ArgTrp: 0.957 ± 0.013	1.754ArgTyr: 1.754 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.617SerAla: 6.617 ± 0.037	0.927SerCys: 0.927 ± 0.014	4.227SerAsp: 4.227 ± 0.035	4.067SerGlu: 4.067 ± 0.03	2.979SerPhe: 2.979 ± 0.023	5.3SerGly: 5.3 ± 0.033	1.963SerHis: 1.963 ± 0.018	3.983SerIle: 3.983 ± 0.025	3.795SerLys: 3.795 ± 0.025	6.794SerLeu: 6.794 ± 0.038	1.794SerMet: 1.794 ± 0.018	3.081SerAsn: 3.081 ± 0.024	5.269SerPro: 5.269 ± 0.047	3.194SerGln: 3.194 ± 0.026	4.816SerArg: 4.816 ± 0.037	8.241SerSer: 8.241 ± 0.065	5.669SerThr: 5.669 ± 0.037	4.497SerVal: 4.497 ± 0.028	1.159SerTrp: 1.159 ± 0.014	2.17SerTyr: 2.17 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.288ThrAla: 5.288 ± 0.032	0.842ThrCys: 0.842 ± 0.015	2.902ThrAsp: 2.902 ± 0.022	3.172ThrGlu: 3.172 ± 0.027	2.375ThrPhe: 2.375 ± 0.02	4.096ThrGly: 4.096 ± 0.031	1.375ThrHis: 1.375 ± 0.015	3.235ThrIle: 3.235 ± 0.025	2.858ThrLys: 2.858 ± 0.027	5.248ThrLeu: 5.248 ± 0.03	1.318ThrMet: 1.318 ± 0.013	2.278ThrAsn: 2.278 ± 0.02	4.495ThrPro: 4.495 ± 0.041	2.243ThrGln: 2.243 ± 0.017	3.202ThrArg: 3.202 ± 0.024	5.529ThrSer: 5.529 ± 0.038	4.514ThrThr: 4.514 ± 0.036	3.77ThrVal: 3.77 ± 0.025	0.938ThrTrp: 0.938 ± 0.012	1.752ThrTyr: 1.752 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.265ValAla: 5.265 ± 0.034	0.855ValCys: 0.855 ± 0.013	3.673ValAsp: 3.673 ± 0.026	3.868ValGlu: 3.868 ± 0.027	2.409ValPhe: 2.409 ± 0.024	4.028ValGly: 4.028 ± 0.032	1.426ValHis: 1.426 ± 0.015	2.867ValIle: 2.867 ± 0.027	2.968ValLys: 2.968 ± 0.026	5.447ValLeu: 5.447 ± 0.039	1.363ValMet: 1.363 ± 0.017	2.235ValAsn: 2.235 ± 0.018	3.53ValPro: 3.53 ± 0.026	2.421ValGln: 2.421 ± 0.022	3.378ValArg: 3.378 ± 0.028	4.482ValSer: 4.482 ± 0.031	3.558ValThr: 3.558 ± 0.029	4.261ValVal: 4.261 ± 0.039	0.917ValTrp: 0.917 ± 0.012	1.782ValTyr: 1.782 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.147TrpAla: 1.147 ± 0.014	0.219TrpCys: 0.219 ± 0.007	0.936TrpAsp: 0.936 ± 0.014	0.866TrpGlu: 0.866 ± 0.01	0.572TrpPhe: 0.572 ± 0.01	0.981TrpGly: 0.981 ± 0.013	0.383TrpHis: 0.383 ± 0.008	0.824TrpIle: 0.824 ± 0.011	0.866TrpLys: 0.866 ± 0.012	1.363TrpLeu: 1.363 ± 0.015	0.395TrpMet: 0.395 ± 0.009	0.683TrpAsn: 0.683 ± 0.011	0.645TrpPro: 0.645 ± 0.011	0.613TrpGln: 0.613 ± 0.01	0.966TrpArg: 0.966 ± 0.013	1.132TrpSer: 1.132 ± 0.015	0.968TrpThr: 0.968 ± 0.015	0.91TrpVal: 0.91 ± 0.014	0.299TrpTrp: 0.299 ± 0.008	0.488TrpTyr: 0.488 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.32TyrAla: 2.32 ± 0.023	0.455TyrCys: 0.455 ± 0.009	1.77TyrAsp: 1.77 ± 0.019	1.641TyrGlu: 1.641 ± 0.018	1.232TyrPhe: 1.232 ± 0.015	2.146TyrGly: 2.146 ± 0.023	0.787TyrHis: 0.787 ± 0.012	1.465TyrIle: 1.465 ± 0.018	1.217TyrLys: 1.217 ± 0.014	2.592TyrLeu: 2.592 ± 0.023	0.693TyrMet: 0.693 ± 0.012	1.225TyrAsn: 1.225 ± 0.013	1.543TyrPro: 1.543 ± 0.018	1.164TyrGln: 1.164 ± 0.015	1.657TyrArg: 1.657 ± 0.016	2.099TyrSer: 2.099 ± 0.017	1.767TyrThr: 1.767 ± 0.022	1.71TyrVal: 1.71 ± 0.018	0.489TyrTrp: 0.489 ± 0.012	0.983TyrTyr: 0.983 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13463 proteins (6148114 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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