Amino acid dipepetide frequency for Tacheng Tick Virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.622AlaAla: 4.622 ± 1.361
1.321AlaCys: 1.321 ± 0.877
3.301AlaAsp: 3.301 ± 1.173
4.292AlaGlu: 4.292 ± 1.33
0.66AlaPhe: 0.66 ± 0.438
4.622AlaGly: 4.622 ± 3.177
2.971AlaHis: 2.971 ± 0.66
3.962AlaIle: 3.962 ± 0.71
2.971AlaLys: 2.971 ± 1.077
5.943AlaLeu: 5.943 ± 0.704
1.981AlaMet: 1.981 ± 0.355
1.981AlaAsn: 1.981 ± 0.848
3.301AlaPro: 3.301 ± 1.723
2.641AlaGln: 2.641 ± 1.177
5.612AlaArg: 5.612 ± 2.357
2.971AlaSer: 2.971 ± 0.686
2.971AlaThr: 2.971 ± 0.849
3.632AlaVal: 3.632 ± 2.734
0.66AlaTrp: 0.66 ± 0.438
4.952AlaTyr: 4.952 ± 1.661
0.0AlaXaa: 0.0 ± 0.0
Cys
1.321CysAla: 1.321 ± 0.941
0.33CysCys: 0.33 ± 0.178
0.99CysAsp: 0.99 ± 0.461
0.33CysGlu: 0.33 ± 0.558
0.0CysPhe: 0.0 ± 0.0
0.99CysGly: 0.99 ± 0.369
0.66CysHis: 0.66 ± 0.357
0.66CysIle: 0.66 ± 0.357
0.0CysLys: 0.0 ± 0.0
2.311CysLeu: 2.311 ± 0.467
0.33CysMet: 0.33 ± 0.178
0.99CysAsn: 0.99 ± 0.369
1.981CysPro: 1.981 ± 1.071
1.321CysGln: 1.321 ± 0.517
1.981CysArg: 1.981 ± 1.071
0.99CysSer: 0.99 ± 0.461
0.66CysThr: 0.66 ± 0.357
0.99CysVal: 0.99 ± 0.369
0.0CysTrp: 0.0 ± 0.0
0.66CysTyr: 0.66 ± 0.438
0.0CysXaa: 0.0 ± 0.0
Asp
2.311AspAla: 2.311 ± 1.58
0.33AspCys: 0.33 ± 0.178
1.981AspAsp: 1.981 ± 0.738
2.641AspGlu: 2.641 ± 0.854
0.66AspPhe: 0.66 ± 0.357
1.981AspGly: 1.981 ± 0.892
1.981AspHis: 1.981 ± 0.355
2.971AspIle: 2.971 ± 1.123
1.651AspLys: 1.651 ± 0.682
7.593AspLeu: 7.593 ± 1.047
1.321AspMet: 1.321 ± 0.588
0.99AspAsn: 0.99 ± 0.461
4.292AspPro: 4.292 ± 1.33
1.981AspGln: 1.981 ± 0.659
3.301AspArg: 3.301 ± 0.952
2.971AspSer: 2.971 ± 1.764
1.981AspThr: 1.981 ± 0.723
3.962AspVal: 3.962 ± 0.997
0.99AspTrp: 0.99 ± 0.535
1.981AspTyr: 1.981 ± 1.071
0.0AspXaa: 0.0 ± 0.0
Glu
3.301GluAla: 3.301 ± 0.952
0.33GluCys: 0.33 ± 0.558
4.622GluAsp: 4.622 ± 1.039
2.311GluGlu: 2.311 ± 0.7
1.651GluPhe: 1.651 ± 0.892
2.311GluGly: 2.311 ± 1.782
1.321GluHis: 1.321 ± 0.588
4.622GluIle: 4.622 ± 1.455
2.971GluLys: 2.971 ± 0.829
7.593GluLeu: 7.593 ± 1.79
1.651GluMet: 1.651 ± 0.464
1.981GluAsn: 1.981 ± 1.695
2.311GluPro: 2.311 ± 0.467
2.311GluGln: 2.311 ± 0.902
1.981GluArg: 1.981 ± 0.848
7.263GluSer: 7.263 ± 1.265
5.612GluThr: 5.612 ± 1.735
3.301GluVal: 3.301 ± 0.904
0.99GluTrp: 0.99 ± 0.535
3.301GluTyr: 3.301 ± 1.086
0.0GluXaa: 0.0 ± 0.0
Phe
1.321PheAla: 1.321 ± 0.714
0.33PheCys: 0.33 ± 0.178
1.321PheAsp: 1.321 ± 0.714
2.641PheGlu: 2.641 ± 0.701
0.99PhePhe: 0.99 ± 0.535
1.981PheGly: 1.981 ± 0.723
1.321PheHis: 1.321 ± 0.941
2.311PheIle: 2.311 ± 1.135
0.99PheLys: 0.99 ± 0.988
4.292PheLeu: 4.292 ± 1.33
0.33PheMet: 0.33 ± 0.558
1.981PheAsn: 1.981 ± 0.738
1.321PhePro: 1.321 ± 0.714
1.321PheGln: 1.321 ± 0.38
1.651PheArg: 1.651 ± 0.464
0.99PheSer: 0.99 ± 0.369
1.651PheThr: 1.651 ± 0.452
0.99PheVal: 0.99 ± 0.461
0.33PheTrp: 0.33 ± 0.178
0.99PheTyr: 0.99 ± 0.461
0.0PheXaa: 0.0 ± 0.0
Gly
2.971GlyAla: 2.971 ± 1.66
0.33GlyCys: 0.33 ± 0.542
3.962GlyAsp: 3.962 ± 0.895
3.632GlyGlu: 3.632 ± 1.959
1.651GlyPhe: 1.651 ± 1.423
3.632GlyGly: 3.632 ± 1.329
2.311GlyHis: 2.311 ± 1.249
3.301GlyIle: 3.301 ± 0.428
2.971GlyLys: 2.971 ± 0.849
4.952GlyLeu: 4.952 ± 1.757
0.99GlyMet: 0.99 ± 0.6
0.99GlyAsn: 0.99 ± 0.535
3.301GlyPro: 3.301 ± 2.332
1.651GlyGln: 1.651 ± 1.135
2.641GlyArg: 2.641 ± 1.838
4.292GlySer: 4.292 ± 0.726
3.632GlyThr: 3.632 ± 0.829
3.301GlyVal: 3.301 ± 0.786
0.33GlyTrp: 0.33 ± 0.558
5.943GlyTyr: 5.943 ± 0.96
0.0GlyXaa: 0.0 ± 0.0
His
1.651HisAla: 1.651 ± 0.621
0.33HisCys: 0.33 ± 0.178
1.321HisAsp: 1.321 ± 0.714
1.321HisGlu: 1.321 ± 0.38
1.981HisPhe: 1.981 ± 0.738
1.321HisGly: 1.321 ± 0.714
0.33HisHis: 0.33 ± 0.689
2.971HisIle: 2.971 ± 0.85
0.66HisLys: 0.66 ± 0.357
5.282HisLeu: 5.282 ± 0.73
0.33HisMet: 0.33 ± 0.558
0.33HisAsn: 0.33 ± 0.689
2.641HisPro: 2.641 ± 1.06
0.99HisGln: 0.99 ± 0.535
3.301HisArg: 3.301 ± 1.391
1.321HisSer: 1.321 ± 1.195
2.311HisThr: 2.311 ± 0.683
1.651HisVal: 1.651 ± 0.621
1.321HisTrp: 1.321 ± 0.714
0.33HisTyr: 0.33 ± 0.178
0.0HisXaa: 0.0 ± 0.0
Ile
3.962IleAla: 3.962 ± 0.997
2.311IleCys: 2.311 ± 0.864
3.301IleAsp: 3.301 ± 1.242
3.301IleGlu: 3.301 ± 1.392
1.651IlePhe: 1.651 ± 0.621
1.651IleGly: 1.651 ± 1.022
1.321IleHis: 1.321 ± 0.714
4.292IleIle: 4.292 ± 0.715
6.933IleLys: 6.933 ± 1.052
6.603IleLeu: 6.603 ± 1.817
0.99IleMet: 0.99 ± 0.743
2.311IleAsn: 2.311 ± 0.742
4.292IlePro: 4.292 ± 0.712
1.651IleGln: 1.651 ± 0.682
4.622IleArg: 4.622 ± 1.083
2.971IleSer: 2.971 ± 1.606
2.311IleThr: 2.311 ± 0.467
2.971IleVal: 2.971 ± 1.223
0.33IleTrp: 0.33 ± 0.178
1.651IleTyr: 1.651 ± 0.892
0.0IleXaa: 0.0 ± 0.0
Lys
2.641LysAla: 2.641 ± 1.428
0.33LysCys: 0.33 ± 0.178
2.311LysAsp: 2.311 ± 0.334
3.632LysGlu: 3.632 ± 2.129
1.981LysPhe: 1.981 ± 0.659
2.311LysGly: 2.311 ± 0.334
0.99LysHis: 0.99 ± 0.369
1.981LysIle: 1.981 ± 0.892
1.321LysLys: 1.321 ± 0.877
4.622LysLeu: 4.622 ± 0.841
0.99LysMet: 0.99 ± 0.441
3.962LysAsn: 3.962 ± 0.977
1.321LysPro: 1.321 ± 0.563
1.321LysGln: 1.321 ± 1.364
1.651LysArg: 1.651 ± 0.469
2.311LysSer: 2.311 ± 0.902
1.321LysThr: 1.321 ± 0.588
2.311LysVal: 2.311 ± 0.742
1.321LysTrp: 1.321 ± 0.714
1.981LysTyr: 1.981 ± 0.848
0.0LysXaa: 0.0 ± 0.0
Leu
7.923LeuAla: 7.923 ± 1.713
0.99LeuCys: 0.99 ± 0.535
3.632LeuAsp: 3.632 ± 0.456
8.254LeuGlu: 8.254 ± 2.19
3.632LeuPhe: 3.632 ± 1.018
8.914LeuGly: 8.914 ± 2.281
3.632LeuHis: 3.632 ± 1.05
7.593LeuIle: 7.593 ± 1.306
3.301LeuLys: 3.301 ± 0.91
15.517LeuLeu: 15.517 ± 1.468
3.301LeuMet: 3.301 ± 1.179
3.962LeuAsn: 3.962 ± 0.173
7.593LeuPro: 7.593 ± 1.768
4.622LeuGln: 4.622 ± 0.251
5.612LeuArg: 5.612 ± 2.068
9.574LeuSer: 9.574 ± 2.648
10.565LeuThr: 10.565 ± 1.8
3.962LeuVal: 3.962 ± 0.804
1.651LeuTrp: 1.651 ± 0.892
2.971LeuTyr: 2.971 ± 1.067
0.0LeuXaa: 0.0 ± 0.0
Met
2.311MetAla: 2.311 ± 1.135
0.33MetCys: 0.33 ± 0.542
0.33MetAsp: 0.33 ± 0.178
1.321MetGlu: 1.321 ± 1.17
0.99MetPhe: 0.99 ± 0.535
1.321MetGly: 1.321 ± 0.563
0.66MetHis: 0.66 ± 0.47
1.981MetIle: 1.981 ± 1.071
1.651MetLys: 1.651 ± 1.423
1.981MetLeu: 1.981 ± 0.433
1.651MetMet: 1.651 ± 1.135
0.99MetAsn: 0.99 ± 0.369
1.651MetPro: 1.651 ± 1.386
0.99MetGln: 0.99 ± 1.278
1.321MetArg: 1.321 ± 0.714
2.971MetSer: 2.971 ± 1.034
1.651MetThr: 1.651 ± 0.621
0.99MetVal: 0.99 ± 0.743
0.33MetTrp: 0.33 ± 0.178
0.99MetTyr: 0.99 ± 0.369
0.0MetXaa: 0.0 ± 0.0
Asn
2.641AsnAla: 2.641 ± 0.401
0.99AsnCys: 0.99 ± 0.369
0.99AsnAsp: 0.99 ± 0.535
1.651AsnGlu: 1.651 ± 0.452
0.33AsnPhe: 0.33 ± 0.178
0.33AsnGly: 0.33 ± 0.178
0.66AsnHis: 0.66 ± 0.357
2.311AsnIle: 2.311 ± 0.742
2.311AsnLys: 2.311 ± 1.031
4.952AsnLeu: 4.952 ± 1.395
0.66AsnMet: 0.66 ± 0.357
0.99AsnAsn: 0.99 ± 0.461
2.641AsnPro: 2.641 ± 1.147
1.981AsnGln: 1.981 ± 0.892
1.651AsnArg: 1.651 ± 0.791
1.651AsnSer: 1.651 ± 0.464
1.981AsnThr: 1.981 ± 0.754
1.981AsnVal: 1.981 ± 0.433
0.66AsnTrp: 0.66 ± 0.438
1.651AsnTyr: 1.651 ± 0.791
0.0AsnXaa: 0.0 ± 0.0
Pro
2.641ProAla: 2.641 ± 1.902
0.66ProCys: 0.66 ± 0.357
3.962ProAsp: 3.962 ± 0.866
2.971ProGlu: 2.971 ± 0.66
1.981ProPhe: 1.981 ± 0.433
4.292ProGly: 4.292 ± 1.33
2.311ProHis: 2.311 ± 1.249
2.311ProIle: 2.311 ± 0.467
2.971ProLys: 2.971 ± 1.823
5.943ProLeu: 5.943 ± 0.783
1.651ProMet: 1.651 ± 1.363
0.99ProAsn: 0.99 ± 0.535
5.282ProPro: 5.282 ± 1.757
1.981ProGln: 1.981 ± 0.892
1.651ProArg: 1.651 ± 0.621
4.292ProSer: 4.292 ± 0.712
6.603ProThr: 6.603 ± 0.968
4.622ProVal: 4.622 ± 0.816
0.66ProTrp: 0.66 ± 0.357
0.66ProTyr: 0.66 ± 0.837
0.0ProXaa: 0.0 ± 0.0
Gln
3.962GlnAla: 3.962 ± 1.654
0.99GlnCys: 0.99 ± 0.369
0.66GlnAsp: 0.66 ± 0.598
3.962GlnGlu: 3.962 ± 0.559
0.66GlnPhe: 0.66 ± 0.357
1.321GlnGly: 1.321 ± 0.714
1.321GlnHis: 1.321 ± 0.559
2.311GlnIle: 2.311 ± 0.993
1.321GlnLys: 1.321 ± 0.38
4.952GlnLeu: 4.952 ± 3.202
0.33GlnMet: 0.33 ± 0.44
0.66GlnAsn: 0.66 ± 0.357
1.321GlnPro: 1.321 ± 1.164
2.971GlnGln: 2.971 ± 1.346
1.321GlnArg: 1.321 ± 0.714
2.641GlnSer: 2.641 ± 1.118
2.971GlnThr: 2.971 ± 0.849
3.962GlnVal: 3.962 ± 0.7
0.33GlnTrp: 0.33 ± 0.178
2.311GlnTyr: 2.311 ± 0.782
0.0GlnXaa: 0.0 ± 0.0
Arg
2.641ArgAla: 2.641 ± 0.901
2.641ArgCys: 2.641 ± 1.428
3.632ArgAsp: 3.632 ± 0.831
2.971ArgGlu: 2.971 ± 0.309
1.981ArgPhe: 1.981 ± 0.355
2.971ArgGly: 2.971 ± 1.168
1.651ArgHis: 1.651 ± 0.621
3.301ArgIle: 3.301 ± 1.706
0.99ArgLys: 0.99 ± 0.369
7.593ArgLeu: 7.593 ± 1.018
0.33ArgMet: 0.33 ± 0.542
1.321ArgAsn: 1.321 ± 0.877
1.651ArgPro: 1.651 ± 0.452
3.632ArgGln: 3.632 ± 0.846
5.612ArgArg: 5.612 ± 2.007
3.962ArgSer: 3.962 ± 1.345
3.632ArgThr: 3.632 ± 1.963
6.603ArgVal: 6.603 ± 0.855
0.66ArgTrp: 0.66 ± 0.438
2.311ArgTyr: 2.311 ± 0.902
0.0ArgXaa: 0.0 ± 0.0
Ser
3.962SerAla: 3.962 ± 3.507
1.321SerCys: 1.321 ± 0.517
3.632SerAsp: 3.632 ± 0.723
7.923SerGlu: 7.923 ± 2.822
1.321SerPhe: 1.321 ± 0.517
5.943SerGly: 5.943 ± 4.795
3.301SerHis: 3.301 ± 1.242
3.301SerIle: 3.301 ± 1.306
1.981SerLys: 1.981 ± 1.071
6.273SerLeu: 6.273 ± 0.679
1.981SerMet: 1.981 ± 0.355
2.641SerAsn: 2.641 ± 1.497
3.301SerPro: 3.301 ± 1.391
2.971SerGln: 2.971 ± 0.677
5.282SerArg: 5.282 ± 1.803
7.593SerSer: 7.593 ± 1.455
4.292SerThr: 4.292 ± 0.121
2.971SerVal: 2.971 ± 0.686
1.651SerTrp: 1.651 ± 0.892
2.641SerTyr: 2.641 ± 0.401
0.0SerXaa: 0.0 ± 0.0
Thr
4.622ThrAla: 4.622 ± 1.004
0.99ThrCys: 0.99 ± 0.535
2.641ThrAsp: 2.641 ± 1.941
2.641ThrGlu: 2.641 ± 0.759
2.641ThrPhe: 2.641 ± 0.854
3.301ThrGly: 3.301 ± 1.086
1.981ThrHis: 1.981 ± 0.659
4.622ThrIle: 4.622 ± 1.489
0.66ThrLys: 0.66 ± 0.357
7.593ThrLeu: 7.593 ± 1.29
3.301ThrMet: 3.301 ± 0.929
2.971ThrAsn: 2.971 ± 0.686
3.301ThrPro: 3.301 ± 0.671
2.311ThrGln: 2.311 ± 0.85
4.622ThrArg: 4.622 ± 1.483
6.603ThrSer: 6.603 ± 0.99
2.971ThrThr: 2.971 ± 1.147
2.641ThrVal: 2.641 ± 1.672
0.33ThrTrp: 0.33 ± 0.178
2.971ThrTyr: 2.971 ± 0.85
0.0ThrXaa: 0.0 ± 0.0
Val
3.962ValAla: 3.962 ± 1.964
1.651ValCys: 1.651 ± 0.892
2.641ValAsp: 2.641 ± 0.388
2.971ValGlu: 2.971 ± 0.523
1.321ValPhe: 1.321 ± 0.38
4.622ValGly: 4.622 ± 0.565
1.321ValHis: 1.321 ± 0.748
2.311ValIle: 2.311 ± 1.249
2.971ValLys: 2.971 ± 0.686
5.943ValLeu: 5.943 ± 1.826
3.301ValMet: 3.301 ± 0.786
0.99ValAsn: 0.99 ± 0.535
3.632ValPro: 3.632 ± 0.456
1.651ValGln: 1.651 ± 0.621
3.962ValArg: 3.962 ± 1.368
5.612ValSer: 5.612 ± 0.679
2.641ValThr: 2.641 ± 0.901
4.622ValVal: 4.622 ± 1.198
0.99ValTrp: 0.99 ± 0.461
2.641ValTyr: 2.641 ± 0.701
0.0ValXaa: 0.0 ± 0.0
Trp
0.99TrpAla: 0.99 ± 0.369
0.33TrpCys: 0.33 ± 0.178
0.33TrpAsp: 0.33 ± 0.178
0.66TrpGlu: 0.66 ± 0.357
0.33TrpPhe: 0.33 ± 0.542
0.99TrpGly: 0.99 ± 0.535
0.0TrpHis: 0.0 ± 0.0
0.33TrpIle: 0.33 ± 0.178
1.321TrpLys: 1.321 ± 0.714
1.321TrpLeu: 1.321 ± 0.714
0.0TrpMet: 0.0 ± 0.0
1.321TrpAsn: 1.321 ± 0.38
1.321TrpPro: 1.321 ± 0.38
0.33TrpGln: 0.33 ± 0.558
0.99TrpArg: 0.99 ± 0.535
0.33TrpSer: 0.33 ± 0.178
0.66TrpThr: 0.66 ± 0.357
0.99TrpVal: 0.99 ± 0.535
0.0TrpTrp: 0.0 ± 0.0
0.99TrpTyr: 0.99 ± 0.535
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.612TyrAla: 5.612 ± 1.567
0.66TyrCys: 0.66 ± 0.47
2.311TyrAsp: 2.311 ± 0.782
2.311TyrGlu: 2.311 ± 0.467
2.641TyrPhe: 2.641 ± 1.428
2.311TyrGly: 2.311 ± 0.7
1.651TyrHis: 1.651 ± 0.892
1.981TyrIle: 1.981 ± 0.754
0.66TyrLys: 0.66 ± 0.357
5.943TyrLeu: 5.943 ± 1.637
0.66TyrMet: 0.66 ± 0.395
0.66TyrAsn: 0.66 ± 0.357
1.981TyrPro: 1.981 ± 0.94
1.651TyrGln: 1.651 ± 1.022
1.321TyrArg: 1.321 ± 0.714
2.971TyrSer: 2.971 ± 1.223
3.301TyrThr: 3.301 ± 0.665
3.301TyrVal: 3.301 ± 0.665
0.0TyrTrp: 0.0 ± 0.0
1.321TyrTyr: 1.321 ± 0.588
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3030 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski