Candida auris (Yeast)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Saccharomycotina; Saccharomycetes; Saccharomycetales; Metschnikowiaceae;

Average proteome isoelectric point is 6.44

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5409 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2H0ZR33|A0A2H0ZR33_CANAR Uncharacterized protein OS=Candida auris OX=498019 GN=B9J08_002729 PE=4 SV=1
MM1 pKa = 7.57KK2 pKa = 10.38LLSTVATAALLLQKK16 pKa = 10.49ARR18 pKa = 11.84SLTITEE24 pKa = 4.23DD25 pKa = 3.51TVLVSPVNLEE35 pKa = 3.67IGEE38 pKa = 4.44LNINPGVYY46 pKa = 10.31FSIVNNVLTVLGGNLNNDD64 pKa = 3.23GAFYY68 pKa = 9.77VTSTNGLAASVTIASGSIINRR89 pKa = 11.84GDD91 pKa = 3.29LAFNSLKK98 pKa = 11.12ANVITNFNLDD108 pKa = 3.45SVGTFSNTGNMWLGVPIFSAVPPIILGSALDD139 pKa = 3.87WEE141 pKa = 4.77NKK143 pKa = 8.73GMIYY147 pKa = 10.4LRR149 pKa = 11.84QEE151 pKa = 3.94LGGASPITISQVLGAIDD168 pKa = 3.82NSGTICIEE176 pKa = 3.84RR177 pKa = 11.84LNWLQTTTINGAGCVNVQADD197 pKa = 3.72GHH199 pKa = 6.3LQLQISPWSVGEE211 pKa = 4.0DD212 pKa = 3.09QTIYY216 pKa = 11.12LSTPTSALSVLGLEE230 pKa = 4.48PSLLGTKK237 pKa = 9.05TYY239 pKa = 11.13NVVGFGGGNTIGINLGFTSYY259 pKa = 10.56SYY261 pKa = 11.12SGSTLTLSFFLGVFKK276 pKa = 10.9INFNIGEE283 pKa = 4.58GYY285 pKa = 10.06SADD288 pKa = 3.37GFSTNGPGNSGTQITYY304 pKa = 10.21DD305 pKa = 3.37GPYY308 pKa = 9.31PGSVPDD314 pKa = 3.87KK315 pKa = 10.07CLCKK319 pKa = 10.57DD320 pKa = 3.9FPTPPTEE327 pKa = 4.35PSSSSSSSSSAPPSSSAPEE346 pKa = 3.86SSSTSEE352 pKa = 4.09SSSSEE357 pKa = 3.92SSSSSEE363 pKa = 4.02PPSSEE368 pKa = 4.07TSSSEE373 pKa = 4.15PPSSSQPPSSSEE385 pKa = 3.94PPSSSEE391 pKa = 4.42PPSSSQPPSSSQPPSSSEE409 pKa = 3.94PPSSSEE415 pKa = 4.42PPSSSQPPSSSEE427 pKa = 4.05PPSSSGPSEE436 pKa = 4.19SSGSSSGPSEE446 pKa = 4.2TSGSSSGPSEE456 pKa = 4.17TSGSSTGPSEE466 pKa = 3.93TSGPSEE472 pKa = 4.36SSTGPGNGGEE482 pKa = 4.23TSGPGNGGEE491 pKa = 4.28TSTGPGNGGQPTSGPGNGGEE511 pKa = 4.08PTGPGNGGEE520 pKa = 4.11PTGPGNGGEE529 pKa = 4.11PTGPGNGGQPTGPGNGGEE547 pKa = 4.11PTGPGNGGQPTGPGNGGQPTGPGNGGQPTGPGNGGQPTNGPGNGGQPTGPGGPSEE602 pKa = 4.09TAPGGGNGGGNGNGGGNGNGGGNGNGGGNGNGGEE636 pKa = 4.08NGNGGGNGNGGGNGNGGEE654 pKa = 4.07NGNGGEE660 pKa = 4.17NGNGGGNGTGGEE672 pKa = 4.07NGNGGGNGNGGGNGSGNGSGNGSGNGSGNGSGNGSGNGNGSGNGIEE718 pKa = 4.58TKK720 pKa = 10.03TSQSPTGGAGGPTVSSYY737 pKa = 11.52EE738 pKa = 4.02GGASIATFGLTGFISIVLLMLVV760 pKa = 3.79

Molecular weight: 72.27 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2H0ZCE9|A0A2H0ZCE9_CANAR Uncharacterized protein OS=Candida auris OX=498019 GN=B9J08_005011 PE=3 SV=1
MM1 pKa = 7.66IYY3 pKa = 9.12STTSRR8 pKa = 11.84LPAKK12 pKa = 10.52SKK14 pKa = 11.02GPLSKK19 pKa = 9.91RR20 pKa = 11.84TRR22 pKa = 11.84CRR24 pKa = 11.84HH25 pKa = 4.95FPYY28 pKa = 10.45SEE30 pKa = 4.36LKK32 pKa = 10.54LLHH35 pKa = 6.51TSTEE39 pKa = 4.03ATDD42 pKa = 3.07KK43 pKa = 10.73SKK45 pKa = 10.85RR46 pKa = 11.84YY47 pKa = 9.41RR48 pKa = 11.84PRR50 pKa = 11.84NQFMMARR57 pKa = 11.84QHH59 pKa = 5.63LTSTFKK65 pKa = 10.81DD66 pKa = 3.94GRR68 pKa = 11.84CARR71 pKa = 11.84VKK73 pKa = 10.38SIRR76 pKa = 11.84ASQVCSLSCRR86 pKa = 11.84FSSGLLRR93 pKa = 11.84NTVRR97 pKa = 11.84TKK99 pKa = 10.25FNCTVSMQYY108 pKa = 11.14SSIASCEE115 pKa = 4.0LSLQGCQISGAVEE128 pKa = 3.73TAGSKK133 pKa = 9.4KK134 pKa = 10.31RR135 pKa = 11.84KK136 pKa = 8.74IFLWLTGGRR145 pKa = 11.84CGTFSSMQILRR156 pKa = 11.84KK157 pKa = 9.92GG158 pKa = 3.23

Molecular weight: 17.79 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5409

0

5409

2694904

66

4946

498.2

55.93

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.699 ± 0.033

1.142 ± 0.012

5.899 ± 0.023

6.837 ± 0.037

4.398 ± 0.02

5.489 ± 0.033

2.327 ± 0.015

5.602 ± 0.021

6.878 ± 0.033

9.265 ± 0.034

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.05 ± 0.01

4.839 ± 0.02

4.721 ± 0.029

3.932 ± 0.025

4.763 ± 0.023

9.177 ± 0.042

5.445 ± 0.041

6.217 ± 0.024

1.07 ± 0.01

3.249 ± 0.018
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski