Amino acid dipepetide frequency for Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis agent) (Calyptromyces circinelloides)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.934AlaAla: 6.934 ± 0.066	1.008AlaCys: 1.008 ± 0.014	3.502AlaAsp: 3.502 ± 0.025	3.946AlaGlu: 3.946 ± 0.032	2.744AlaPhe: 2.744 ± 0.023	3.505AlaGly: 3.505 ± 0.035	1.464AlaHis: 1.464 ± 0.018	4.459AlaIle: 4.459 ± 0.03	4.215AlaLys: 4.215 ± 0.032	6.477AlaLeu: 6.477 ± 0.049	1.833AlaMet: 1.833 ± 0.019	3.323AlaAsn: 3.323 ± 0.026	3.219AlaPro: 3.219 ± 0.032	2.834AlaGln: 2.834 ± 0.034	3.008AlaArg: 3.008 ± 0.029	6.359AlaSer: 6.359 ± 0.041	5.035AlaThr: 5.035 ± 0.038	4.37AlaVal: 4.37 ± 0.038	0.718AlaTrp: 0.718 ± 0.012	2.162AlaTyr: 2.162 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.8CysAla: 0.8 ± 0.013	0.312CysCys: 0.312 ± 0.008	0.712CysAsp: 0.712 ± 0.012	0.636CysGlu: 0.636 ± 0.012	0.633CysPhe: 0.633 ± 0.012	0.847CysGly: 0.847 ± 0.014	0.4CysHis: 0.4 ± 0.01	0.937CysIle: 0.937 ± 0.013	0.792CysLys: 0.792 ± 0.016	1.347CysLeu: 1.347 ± 0.017	0.32CysMet: 0.32 ± 0.008	0.626CysAsn: 0.626 ± 0.012	0.645CysPro: 0.645 ± 0.015	0.593CysGln: 0.593 ± 0.011	0.707CysArg: 0.707 ± 0.011	1.057CysSer: 1.057 ± 0.017	0.741CysThr: 0.741 ± 0.011	0.826CysVal: 0.826 ± 0.014	0.178CysTrp: 0.178 ± 0.006	0.491CysTyr: 0.491 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	3.966AspAla: 3.966 ± 0.03	0.674AspCys: 0.674 ± 0.012	4.92AspAsp: 4.92 ± 0.049	4.689AspGlu: 4.689 ± 0.044	2.354AspPhe: 2.354 ± 0.023	2.879AspGly: 2.879 ± 0.028	1.394AspHis: 1.394 ± 0.017	3.889AspIle: 3.889 ± 0.03	3.224AspLys: 3.224 ± 0.031	5.157AspLeu: 5.157 ± 0.04	1.594AspMet: 1.594 ± 0.019	2.695AspAsn: 2.695 ± 0.025	2.594AspPro: 2.594 ± 0.025	2.566AspGln: 2.566 ± 0.025	2.435AspArg: 2.435 ± 0.025	3.949AspSer: 3.949 ± 0.033	3.384AspThr: 3.384 ± 0.026	3.496AspVal: 3.496 ± 0.029	0.704AspTrp: 0.704 ± 0.013	2.095AspTyr: 2.095 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.406GluAla: 4.406 ± 0.031	0.7GluCys: 0.7 ± 0.011	4.363GluAsp: 4.363 ± 0.044	6.201GluGlu: 6.201 ± 0.059	2.218GluPhe: 2.218 ± 0.023	2.63GluGly: 2.63 ± 0.025	1.474GluHis: 1.474 ± 0.017	3.432GluIle: 3.432 ± 0.028	4.721GluLys: 4.721 ± 0.041	5.406GluLeu: 5.406 ± 0.038	1.501GluMet: 1.501 ± 0.017	3.057GluAsn: 3.057 ± 0.022	2.202GluPro: 2.202 ± 0.022	3.196GluGln: 3.196 ± 0.029	3.118GluArg: 3.118 ± 0.03	4.262GluSer: 4.262 ± 0.032	3.337GluThr: 3.337 ± 0.032	2.849GluVal: 2.849 ± 0.028	0.686GluTrp: 0.686 ± 0.012	2.056GluTyr: 2.056 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.673PheAla: 2.673 ± 0.024	0.646PheCys: 0.646 ± 0.013	2.601PheAsp: 2.601 ± 0.021	2.398PheGlu: 2.398 ± 0.021	1.713PhePhe: 1.713 ± 0.022	2.576PheGly: 2.576 ± 0.031	0.917PheHis: 0.917 ± 0.014	2.399PheIle: 2.399 ± 0.023	2.2PheLys: 2.2 ± 0.022	3.452PheLeu: 3.452 ± 0.028	1.053PheMet: 1.053 ± 0.015	1.952PheAsn: 1.952 ± 0.021	1.604PhePro: 1.604 ± 0.021	1.53PheGln: 1.53 ± 0.016	1.628PheArg: 1.628 ± 0.019	3.126PheSer: 3.126 ± 0.023	2.243PheThr: 2.243 ± 0.019	2.625PheVal: 2.625 ± 0.026	0.526PheTrp: 0.526 ± 0.013	1.488PheTyr: 1.488 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	3.262GlyAla: 3.262 ± 0.034	0.749GlyCys: 0.749 ± 0.013	2.679GlyAsp: 2.679 ± 0.028	2.506GlyGlu: 2.506 ± 0.021	2.372GlyPhe: 2.372 ± 0.03	3.753GlyGly: 3.753 ± 0.05	1.373GlyHis: 1.373 ± 0.017	3.178GlyIle: 3.178 ± 0.027	3.086GlyLys: 3.086 ± 0.026	4.507GlyLeu: 4.507 ± 0.034	1.189GlyMet: 1.189 ± 0.018	2.385GlyAsn: 2.385 ± 0.022	1.77GlyPro: 1.77 ± 0.02	1.956GlyGln: 1.956 ± 0.022	2.428GlyArg: 2.428 ± 0.027	4.204GlySer: 4.204 ± 0.035	2.82GlyThr: 2.82 ± 0.025	3.191GlyVal: 3.191 ± 0.029	0.723GlyTrp: 0.723 ± 0.013	2.0GlyTyr: 2.0 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.552HisAla: 1.552 ± 0.018	0.429HisCys: 0.429 ± 0.01	1.342HisAsp: 1.342 ± 0.016	1.27HisGlu: 1.27 ± 0.015	1.039HisPhe: 1.039 ± 0.013	1.294HisGly: 1.294 ± 0.016	1.406HisHis: 1.406 ± 0.028	1.51HisIle: 1.51 ± 0.017	1.266HisLys: 1.266 ± 0.019	2.433HisLeu: 2.433 ± 0.023	0.606HisMet: 0.606 ± 0.013	1.153HisAsn: 1.153 ± 0.016	1.453HisPro: 1.453 ± 0.019	1.636HisGln: 1.636 ± 0.023	1.361HisArg: 1.361 ± 0.018	1.915HisSer: 1.915 ± 0.022	1.398HisThr: 1.398 ± 0.019	1.56HisVal: 1.56 ± 0.016	0.294HisTrp: 0.294 ± 0.007	0.938HisTyr: 0.938 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	4.288IleAla: 4.288 ± 0.033	0.895IleCys: 0.895 ± 0.013	3.661IleAsp: 3.661 ± 0.029	3.635IleGlu: 3.635 ± 0.028	2.226IlePhe: 2.226 ± 0.024	2.917IleGly: 2.917 ± 0.027	1.591IleHis: 1.591 ± 0.02	3.41IleIle: 3.41 ± 0.03	3.715IleLys: 3.715 ± 0.029	5.113IleLeu: 5.113 ± 0.037	1.433IleMet: 1.433 ± 0.016	2.737IleAsn: 2.737 ± 0.024	3.095IlePro: 3.095 ± 0.024	2.734IleGln: 2.734 ± 0.027	2.818IleArg: 2.818 ± 0.025	4.454IleSer: 4.454 ± 0.031	3.481IleThr: 3.481 ± 0.027	3.755IleVal: 3.755 ± 0.029	0.671IleTrp: 0.671 ± 0.012	1.933IleTyr: 1.933 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.319LysAla: 4.319 ± 0.028	0.717LysCys: 0.717 ± 0.013	3.546LysAsp: 3.546 ± 0.028	4.482LysGlu: 4.482 ± 0.037	1.983LysPhe: 1.983 ± 0.02	2.591LysGly: 2.591 ± 0.025	1.532LysHis: 1.532 ± 0.019	3.244LysIle: 3.244 ± 0.029	5.661LysLys: 5.661 ± 0.056	5.416LysLeu: 5.416 ± 0.036	1.497LysMet: 1.497 ± 0.018	2.924LysAsn: 2.924 ± 0.027	2.883LysPro: 2.883 ± 0.029	3.158LysGln: 3.158 ± 0.028	3.88LysArg: 3.88 ± 0.029	4.915LysSer: 4.915 ± 0.034	3.552LysThr: 3.552 ± 0.031	3.36LysVal: 3.36 ± 0.029	0.663LysTrp: 0.663 ± 0.011	2.106LysTyr: 2.106 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	6.244LeuAla: 6.244 ± 0.041	1.314LeuCys: 1.314 ± 0.019	5.325LeuAsp: 5.325 ± 0.036	5.575LeuGlu: 5.575 ± 0.044	3.671LeuPhe: 3.671 ± 0.032	4.524LeuGly: 4.524 ± 0.033	2.137LeuHis: 2.137 ± 0.021	4.838LeuIle: 4.838 ± 0.041	5.687LeuLys: 5.687 ± 0.036	8.476LeuLeu: 8.476 ± 0.049	2.213LeuMet: 2.213 ± 0.021	4.244LeuAsn: 4.244 ± 0.031	4.645LeuPro: 4.645 ± 0.032	4.296LeuGln: 4.296 ± 0.035	4.199LeuArg: 4.199 ± 0.033	7.248LeuSer: 7.248 ± 0.04	4.968LeuThr: 4.968 ± 0.029	5.432LeuVal: 5.432 ± 0.041	0.946LeuTrp: 0.946 ± 0.014	2.916LeuTyr: 2.916 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	1.929MetAla: 1.929 ± 0.021	0.285MetCys: 0.285 ± 0.008	1.648MetAsp: 1.648 ± 0.02	1.547MetGlu: 1.547 ± 0.018	0.892MetPhe: 0.892 ± 0.012	1.244MetGly: 1.244 ± 0.016	0.516MetHis: 0.516 ± 0.012	1.395MetIle: 1.395 ± 0.015	1.466MetLys: 1.466 ± 0.018	2.119MetLeu: 2.119 ± 0.023	0.844MetMet: 0.844 ± 0.016	1.311MetAsn: 1.311 ± 0.015	1.185MetPro: 1.185 ± 0.018	1.078MetGln: 1.078 ± 0.014	1.104MetArg: 1.104 ± 0.014	2.192MetSer: 2.192 ± 0.021	1.602MetThr: 1.602 ± 0.018	1.42MetVal: 1.42 ± 0.018	0.244MetTrp: 0.244 ± 0.007	0.766MetTyr: 0.766 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.554AsnAla: 3.554 ± 0.029	0.6AsnCys: 0.6 ± 0.011	2.967AsnAsp: 2.967 ± 0.026	2.93AsnGlu: 2.93 ± 0.025	1.687AsnPhe: 1.687 ± 0.018	2.598AsnGly: 2.598 ± 0.023	1.31AsnHis: 1.31 ± 0.017	2.877AsnIle: 2.877 ± 0.023	2.959AsnLys: 2.959 ± 0.029	3.901AsnLeu: 3.901 ± 0.032	1.33AsnMet: 1.33 ± 0.014	3.49AsnAsn: 3.49 ± 0.043	2.251AsnPro: 2.251 ± 0.022	2.306AsnGln: 2.306 ± 0.024	2.179AsnArg: 2.179 ± 0.021	3.945AsnSer: 3.945 ± 0.037	3.405AsnThr: 3.405 ± 0.03	2.945AsnVal: 2.945 ± 0.025	0.569AsnTrp: 0.569 ± 0.01	1.678AsnTyr: 1.678 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	3.442ProAla: 3.442 ± 0.031	0.487ProCys: 0.487 ± 0.011	2.414ProAsp: 2.414 ± 0.023	2.896ProGlu: 2.896 ± 0.029	1.895ProPhe: 1.895 ± 0.019	1.998ProGly: 1.998 ± 0.026	1.168ProHis: 1.168 ± 0.019	2.735ProIle: 2.735 ± 0.024	2.638ProLys: 2.638 ± 0.027	4.078ProLeu: 4.078 ± 0.028	1.048ProMet: 1.048 ± 0.017	2.426ProAsn: 2.426 ± 0.024	3.846ProPro: 3.846 ± 0.069	2.276ProGln: 2.276 ± 0.028	1.925ProArg: 1.925 ± 0.02	4.93ProSer: 4.93 ± 0.037	3.622ProThr: 3.622 ± 0.032	3.04ProVal: 3.04 ± 0.031	0.449ProTrp: 0.449 ± 0.009	1.494ProTyr: 1.494 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.005GlnAla: 3.005 ± 0.035	0.57GlnCys: 0.57 ± 0.01	2.755GlnAsp: 2.755 ± 0.025	3.098GlnGlu: 3.098 ± 0.029	1.708GlnPhe: 1.708 ± 0.017	1.937GlnGly: 1.937 ± 0.022	1.738GlnHis: 1.738 ± 0.021	2.351GlnIle: 2.351 ± 0.02	2.89GlnLys: 2.89 ± 0.026	4.414GlnLeu: 4.414 ± 0.034	1.11GlnMet: 1.11 ± 0.014	1.949GlnAsn: 1.949 ± 0.021	2.447GlnPro: 2.447 ± 0.032	6.564GlnGln: 6.564 ± 0.128	2.34GlnArg: 2.34 ± 0.024	3.307GlnSer: 3.307 ± 0.024	2.33GlnThr: 2.33 ± 0.021	2.674GlnVal: 2.674 ± 0.025	0.505GlnTrp: 0.505 ± 0.01	1.521GlnTyr: 1.521 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	2.97ArgAla: 2.97 ± 0.023	0.605ArgCys: 0.605 ± 0.012	2.492ArgAsp: 2.492 ± 0.026	2.756ArgGlu: 2.756 ± 0.024	1.95ArgPhe: 1.95 ± 0.019	2.254ArgGly: 2.254 ± 0.026	1.388ArgHis: 1.388 ± 0.018	2.886ArgIle: 2.886 ± 0.024	3.441ArgLys: 3.441 ± 0.028	4.572ArgLeu: 4.572 ± 0.034	1.176ArgMet: 1.176 ± 0.015	2.304ArgAsn: 2.304 ± 0.019	2.161ArgPro: 2.161 ± 0.026	2.384ArgGln: 2.384 ± 0.024	3.342ArgArg: 3.342 ± 0.033	3.743ArgSer: 3.743 ± 0.036	2.409ArgThr: 2.409 ± 0.022	2.611ArgVal: 2.611 ± 0.023	0.567ArgTrp: 0.567 ± 0.01	1.662ArgTyr: 1.662 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	5.676SerAla: 5.676 ± 0.04	1.013SerCys: 1.013 ± 0.015	4.201SerAsp: 4.201 ± 0.033	3.944SerGlu: 3.944 ± 0.037	3.298SerPhe: 3.298 ± 0.028	3.925SerGly: 3.925 ± 0.035	1.89SerHis: 1.89 ± 0.017	5.093SerIle: 5.093 ± 0.036	4.809SerLys: 4.809 ± 0.038	7.049SerLeu: 7.049 ± 0.043	1.97SerMet: 1.97 ± 0.021	4.69SerAsn: 4.69 ± 0.038	4.424SerPro: 4.424 ± 0.053	3.282SerGln: 3.282 ± 0.03	3.749SerArg: 3.749 ± 0.03	10.47SerSer: 10.47 ± 0.109	6.274SerThr: 6.274 ± 0.054	4.743SerVal: 4.743 ± 0.033	0.846SerTrp: 0.846 ± 0.013	2.385SerTyr: 2.385 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	4.95ThrAla: 4.95 ± 0.04	0.853ThrCys: 0.853 ± 0.015	3.031ThrAsp: 3.031 ± 0.024	3.316ThrGlu: 3.316 ± 0.029	2.4ThrPhe: 2.4 ± 0.024	3.104ThrGly: 3.104 ± 0.026	1.429ThrHis: 1.429 ± 0.016	3.715ThrIle: 3.715 ± 0.033	3.426ThrLys: 3.426 ± 0.029	5.477ThrLeu: 5.477 ± 0.034	1.395ThrMet: 1.395 ± 0.017	2.987ThrAsn: 2.987 ± 0.03	3.589ThrPro: 3.589 ± 0.033	2.254ThrGln: 2.254 ± 0.021	2.545ThrArg: 2.545 ± 0.025	5.849ThrSer: 5.849 ± 0.046	5.665ThrThr: 5.665 ± 0.061	3.811ThrVal: 3.811 ± 0.034	0.624ThrTrp: 0.624 ± 0.014	1.734ThrTyr: 1.734 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.371ValAla: 4.371 ± 0.041	0.915ValCys: 0.915 ± 0.014	3.806ValAsp: 3.806 ± 0.03	3.613ValGlu: 3.613 ± 0.032	2.534ValPhe: 2.534 ± 0.024	3.09ValGly: 3.09 ± 0.032	1.443ValHis: 1.443 ± 0.015	3.57ValIle: 3.57 ± 0.033	3.562ValLys: 3.562 ± 0.028	5.362ValLeu: 5.362 ± 0.041	1.478ValMet: 1.478 ± 0.019	2.831ValAsn: 2.831 ± 0.021	2.932ValPro: 2.932 ± 0.025	2.469ValGln: 2.469 ± 0.023	2.611ValArg: 2.611 ± 0.024	4.512ValSer: 4.512 ± 0.031	3.289ValThr: 3.289 ± 0.031	4.048ValVal: 4.048 ± 0.036	0.679ValTrp: 0.679 ± 0.013	2.085ValTyr: 2.085 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	0.668TrpAla: 0.668 ± 0.012	0.184TrpCys: 0.184 ± 0.006	0.694TrpAsp: 0.694 ± 0.014	0.586TrpGlu: 0.586 ± 0.011	0.528TrpPhe: 0.528 ± 0.011	0.561TrpGly: 0.561 ± 0.011	0.287TrpHis: 0.287 ± 0.009	0.757TrpIle: 0.757 ± 0.013	0.769TrpLys: 0.769 ± 0.013	1.014TrpLeu: 1.014 ± 0.015	0.331TrpMet: 0.331 ± 0.007	0.602TrpAsn: 0.602 ± 0.01	0.375TrpPro: 0.375 ± 0.009	0.458TrpGln: 0.458 ± 0.01	0.602TrpArg: 0.602 ± 0.011	0.888TrpSer: 0.888 ± 0.012	0.686TrpThr: 0.686 ± 0.012	0.619TrpVal: 0.619 ± 0.013	0.189TrpTrp: 0.189 ± 0.007	0.387TrpTyr: 0.387 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.102TyrAla: 2.102 ± 0.02	0.643TyrCys: 0.643 ± 0.014	2.0TyrAsp: 2.0 ± 0.02	1.791TyrGlu: 1.791 ± 0.018	1.506TyrPhe: 1.506 ± 0.018	1.905TyrGly: 1.905 ± 0.021	0.996TyrHis: 0.996 ± 0.016	1.888TyrIle: 1.888 ± 0.021	1.899TyrLys: 1.899 ± 0.019	3.128TyrLeu: 3.128 ± 0.03	0.866TyrMet: 0.866 ± 0.012	1.793TyrAsn: 1.793 ± 0.021	1.488TyrPro: 1.488 ± 0.02	1.647TyrGln: 1.647 ± 0.02	1.693TyrArg: 1.693 ± 0.019	2.408TyrSer: 2.408 ± 0.024	1.916TyrThr: 1.916 ± 0.022	1.825TyrVal: 1.825 ± 0.02	0.402TyrTrp: 0.402 ± 0.008	1.462TyrTyr: 1.462 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12143 proteins (5338243 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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