Human papillomavirus type XS2

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 2

Average proteome isoelectric point is 5.71

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|L7YGU6|L7YGU6_9PAPI Major capsid protein L1 OS=Human papillomavirus type XS2 OX=1288116 GN=L1 PE=3 SV=2
MM1 pKa = 7.56HH2 pKa = 7.45GPHH5 pKa = 6.42PTIKK9 pKa = 10.43EE10 pKa = 4.07IEE12 pKa = 4.27LSLAPEE18 pKa = 4.5DD19 pKa = 4.91VPLLCNEE26 pKa = 4.06QLDD29 pKa = 4.04EE30 pKa = 4.49EE31 pKa = 4.91DD32 pKa = 4.59YY33 pKa = 11.35IDD35 pKa = 4.34AVEE38 pKa = 4.53PAQQAYY44 pKa = 9.25RR45 pKa = 11.84VVTQCPKK52 pKa = 10.35CNSPLRR58 pKa = 11.84LVVEE62 pKa = 5.09CSDD65 pKa = 3.19SDD67 pKa = 3.09IRR69 pKa = 11.84AFQEE73 pKa = 4.14LLLGTLKK80 pKa = 10.53LVCPRR85 pKa = 11.84CVV87 pKa = 2.77

Molecular weight:
9.75 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|L7YAW4|L7YAW4_9PAPI Minor capsid protein L2 OS=Human papillomavirus type XS2 OX=1288116 GN=L2 PE=3 SV=1
MM1 pKa = 7.28SRR3 pKa = 11.84DD4 pKa = 3.12TAGPKK9 pKa = 10.32NIFILCRR16 pKa = 11.84DD17 pKa = 3.72CGIPFDD23 pKa = 5.19DD24 pKa = 5.72LRR26 pKa = 11.84LHH28 pKa = 7.4CIYY31 pKa = 9.66CTKK34 pKa = 10.56QLTTAEE40 pKa = 4.32LASFALRR47 pKa = 11.84EE48 pKa = 4.13LNLVWRR54 pKa = 11.84SGAPYY59 pKa = 9.55GACAQCLLLHH69 pKa = 6.74GISRR73 pKa = 11.84RR74 pKa = 11.84LKK76 pKa = 7.75YY77 pKa = 9.65WSYY80 pKa = 9.64SLYY83 pKa = 10.5VEE85 pKa = 4.58GVEE88 pKa = 4.55EE89 pKa = 4.1EE90 pKa = 4.42TKK92 pKa = 10.9EE93 pKa = 5.08SIDD96 pKa = 3.6TQQIRR101 pKa = 11.84CYY103 pKa = 9.72VCHH106 pKa = 6.73KK107 pKa = 10.3PLVKK111 pKa = 10.38EE112 pKa = 4.46EE113 pKa = 4.14KK114 pKa = 10.09DD115 pKa = 3.02KK116 pKa = 11.58HH117 pKa = 6.48RR118 pKa = 11.84DD119 pKa = 3.02EE120 pKa = 4.46RR121 pKa = 11.84RR122 pKa = 11.84RR123 pKa = 11.84LHH125 pKa = 6.9LIAGFWRR132 pKa = 11.84GSCLHH137 pKa = 6.26CWSRR141 pKa = 11.84CTVRR145 pKa = 11.84IPQQ148 pKa = 3.45

Molecular weight:
17.29 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2298

47

660

328.3

36.73

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.092 ± 0.303

2.785 ± 0.732

6.571 ± 0.327

5.614 ± 0.942

3.786 ± 0.409

7.05 ± 0.591

2.089 ± 0.367

4.439 ± 0.389

4.439 ± 0.555

8.399 ± 1.098

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.654 ± 0.221

2.872 ± 0.333

6.223 ± 0.929

4.352 ± 0.717

6.092 ± 0.419

7.137 ± 0.588

7.746 ± 1.2

7.05 ± 0.723

1.654 ± 0.291

3.96 ± 0.285

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski