Human papillomavirus type XS2
Average proteome isoelectric point is 5.71
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|L7YGU6|L7YGU6_9PAPI Major capsid protein L1 OS=Human papillomavirus type XS2 OX=1288116 GN=L1 PE=3 SV=2
MM1 pKa = 7.56 HH2 pKa = 7.45 GPHH5 pKa = 6.42 PTIKK9 pKa = 10.43 EE10 pKa = 4.07 IEE12 pKa = 4.27 LSLAPEE18 pKa = 4.5 DD19 pKa = 4.91 VPLLCNEE26 pKa = 4.06 QLDD29 pKa = 4.04 EE30 pKa = 4.49 EE31 pKa = 4.91 DD32 pKa = 4.59 YY33 pKa = 11.35 IDD35 pKa = 4.34 AVEE38 pKa = 4.53 PAQQAYY44 pKa = 9.25 RR45 pKa = 11.84 VVTQCPKK52 pKa = 10.35 CNSPLRR58 pKa = 11.84 LVVEE62 pKa = 5.09 CSDD65 pKa = 3.19 SDD67 pKa = 3.09 IRR69 pKa = 11.84 AFQEE73 pKa = 4.14 LLLGTLKK80 pKa = 10.53 LVCPRR85 pKa = 11.84 CVV87 pKa = 2.77
Molecular weight: 9.75 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 4.189
IPC2_protein 4.52
IPC_protein 4.38
Toseland 4.228
ProMoST 4.495
Dawson 4.329
Bjellqvist 4.482
Wikipedia 4.202
Rodwell 4.228
Grimsley 4.139
Solomon 4.317
Lehninger 4.279
Nozaki 4.444
DTASelect 4.571
Thurlkill 4.24
EMBOSS 4.215
Sillero 4.495
Patrickios 2.003
IPC_peptide 4.329
IPC2_peptide 4.482
IPC2.peptide.svr19 4.423
Protein with the highest isoelectric point:
>tr|L7YAW4|L7YAW4_9PAPI Minor capsid protein L2 OS=Human papillomavirus type XS2 OX=1288116 GN=L2 PE=3 SV=1
MM1 pKa = 7.28 SRR3 pKa = 11.84 DD4 pKa = 3.12 TAGPKK9 pKa = 10.32 NIFILCRR16 pKa = 11.84 DD17 pKa = 3.72 CGIPFDD23 pKa = 5.19 DD24 pKa = 5.72 LRR26 pKa = 11.84 LHH28 pKa = 7.4 CIYY31 pKa = 9.66 CTKK34 pKa = 10.56 QLTTAEE40 pKa = 4.32 LASFALRR47 pKa = 11.84 EE48 pKa = 4.13 LNLVWRR54 pKa = 11.84 SGAPYY59 pKa = 9.55 GACAQCLLLHH69 pKa = 6.74 GISRR73 pKa = 11.84 RR74 pKa = 11.84 LKK76 pKa = 7.75 YY77 pKa = 9.65 WSYY80 pKa = 9.64 SLYY83 pKa = 10.5 VEE85 pKa = 4.58 GVEE88 pKa = 4.55 EE89 pKa = 4.1 EE90 pKa = 4.42 TKK92 pKa = 10.9 EE93 pKa = 5.08 SIDD96 pKa = 3.6 TQQIRR101 pKa = 11.84 CYY103 pKa = 9.72 VCHH106 pKa = 6.73 KK107 pKa = 10.3 PLVKK111 pKa = 10.38 EE112 pKa = 4.46 EE113 pKa = 4.14 KK114 pKa = 10.09 DD115 pKa = 3.02 KK116 pKa = 11.58 HH117 pKa = 6.48 RR118 pKa = 11.84 DD119 pKa = 3.02 EE120 pKa = 4.46 RR121 pKa = 11.84 RR122 pKa = 11.84 RR123 pKa = 11.84 LHH125 pKa = 6.9 LIAGFWRR132 pKa = 11.84 GSCLHH137 pKa = 6.26 CWSRR141 pKa = 11.84 CTVRR145 pKa = 11.84 IPQQ148 pKa = 3.45
Molecular weight: 17.29 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 7.738
IPC2_protein 7.775
IPC_protein 7.6
Toseland 7.088
ProMoST 8.17
Dawson 8.273
Bjellqvist 8.785
Wikipedia 8.185
Rodwell 8.287
Grimsley 7.088
Solomon 8.346
Lehninger 8.375
Nozaki 9.107
DTASelect 8.419
Thurlkill 8.463
EMBOSS 8.492
Sillero 8.858
Patrickios 3.999
IPC_peptide 8.346
IPC2_peptide 8.214
IPC2.peptide.svr19 8.215
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
7
0
7
2298
47
660
328.3
36.73
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
6.092 ± 0.303
2.785 ± 0.732
6.571 ± 0.327
5.614 ± 0.942
3.786 ± 0.409
7.05 ± 0.591
2.089 ± 0.367
4.439 ± 0.389
4.439 ± 0.555
8.399 ± 1.098
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
1.654 ± 0.221
2.872 ± 0.333
6.223 ± 0.929
4.352 ± 0.717
6.092 ± 0.419
7.137 ± 0.588
7.746 ± 1.2
7.05 ± 0.723
1.654 ± 0.291
3.96 ± 0.285
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here