Amino acid dipepetide frequency for Mucilaginibacter gotjawali

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.862AlaAla: 6.862 ± 0.08	0.724AlaCys: 0.724 ± 0.022	4.755AlaAsp: 4.755 ± 0.065	4.236AlaGlu: 4.236 ± 0.064	3.732AlaPhe: 3.732 ± 0.057	6.3AlaGly: 6.3 ± 0.068	1.298AlaHis: 1.298 ± 0.032	5.862AlaIle: 5.862 ± 0.079	4.754AlaLys: 4.754 ± 0.065	7.111AlaLeu: 7.111 ± 0.085	1.773AlaMet: 1.773 ± 0.038	3.91AlaAsn: 3.91 ± 0.068	2.524AlaPro: 2.524 ± 0.046	2.873AlaGln: 2.873 ± 0.051	2.619AlaArg: 2.619 ± 0.05	4.52AlaSer: 4.52 ± 0.069	4.174AlaThr: 4.174 ± 0.08	5.132AlaVal: 5.132 ± 0.066	0.858AlaTrp: 0.858 ± 0.03	3.062AlaTyr: 3.062 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.59CysAla: 0.59 ± 0.02	0.151CysCys: 0.151 ± 0.01	0.427CysAsp: 0.427 ± 0.018	0.372CysGlu: 0.372 ± 0.02	0.496CysPhe: 0.496 ± 0.021	0.665CysGly: 0.665 ± 0.021	0.188CysHis: 0.188 ± 0.012	0.629CysIle: 0.629 ± 0.022	0.52CysLys: 0.52 ± 0.019	0.895CysLeu: 0.895 ± 0.026	0.221CysMet: 0.221 ± 0.011	0.441CysAsn: 0.441 ± 0.021	0.343CysPro: 0.343 ± 0.015	0.221CysGln: 0.221 ± 0.012	0.359CysArg: 0.359 ± 0.016	0.522CysSer: 0.522 ± 0.023	0.452CysThr: 0.452 ± 0.02	0.495CysVal: 0.495 ± 0.019	0.106CysTrp: 0.106 ± 0.009	0.346CysTyr: 0.346 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.061AspAla: 4.061 ± 0.063	0.428AspCys: 0.428 ± 0.019	2.78AspAsp: 2.78 ± 0.052	3.424AspGlu: 3.424 ± 0.056	3.12AspPhe: 3.12 ± 0.05	3.898AspGly: 3.898 ± 0.067	1.11AspHis: 1.11 ± 0.03	3.972AspIle: 3.972 ± 0.058	3.811AspLys: 3.811 ± 0.052	4.979AspLeu: 4.979 ± 0.074	1.198AspMet: 1.198 ± 0.031	2.884AspAsn: 2.884 ± 0.047	2.327AspPro: 2.327 ± 0.047	1.807AspGln: 1.807 ± 0.035	1.922AspArg: 1.922 ± 0.041	2.883AspSer: 2.883 ± 0.054	2.859AspThr: 2.859 ± 0.051	3.286AspVal: 3.286 ± 0.049	0.797AspTrp: 0.797 ± 0.023	2.571AspTyr: 2.571 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	3.891GluAla: 3.891 ± 0.067	0.326GluCys: 0.326 ± 0.015	2.544GluAsp: 2.544 ± 0.053	3.217GluGlu: 3.217 ± 0.07	2.338GluPhe: 2.338 ± 0.043	3.064GluGly: 3.064 ± 0.049	1.013GluHis: 1.013 ± 0.029	4.169GluIle: 4.169 ± 0.069	4.432GluLys: 4.432 ± 0.073	5.383GluLeu: 5.383 ± 0.092	1.468GluMet: 1.468 ± 0.033	3.086GluAsn: 3.086 ± 0.049	1.665GluPro: 1.665 ± 0.039	2.16GluGln: 2.16 ± 0.04	2.245GluArg: 2.245 ± 0.046	2.555GluSer: 2.555 ± 0.045	2.79GluThr: 2.79 ± 0.052	3.323GluVal: 3.323 ± 0.061	0.633GluTrp: 0.633 ± 0.023	1.985GluTyr: 1.985 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.596PheAla: 3.596 ± 0.051	0.539PheCys: 0.539 ± 0.019	3.009PheAsp: 3.009 ± 0.049	2.67PheGlu: 2.67 ± 0.048	2.599PhePhe: 2.599 ± 0.052	3.493PheGly: 3.493 ± 0.05	0.865PheHis: 0.865 ± 0.026	3.786PheIle: 3.786 ± 0.064	3.427PheLys: 3.427 ± 0.057	4.407PheLeu: 4.407 ± 0.066	1.18PheMet: 1.18 ± 0.029	3.152PheAsn: 3.152 ± 0.049	1.79PhePro: 1.79 ± 0.035	1.312PheGln: 1.312 ± 0.03	1.708PheArg: 1.708 ± 0.036	3.671PheSer: 3.671 ± 0.054	3.247PheThr: 3.247 ± 0.048	2.848PheVal: 2.848 ± 0.045	0.62PheTrp: 0.62 ± 0.024	2.196PheTyr: 2.196 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.989GlyAla: 4.989 ± 0.082	0.639GlyCys: 0.639 ± 0.025	3.639GlyAsp: 3.639 ± 0.067	3.304GlyGlu: 3.304 ± 0.055	3.792GlyPhe: 3.792 ± 0.064	5.105GlyGly: 5.105 ± 0.104	1.372GlyHis: 1.372 ± 0.026	5.581GlyIle: 5.581 ± 0.072	5.231GlyLys: 5.231 ± 0.069	6.467GlyLeu: 6.467 ± 0.078	1.715GlyMet: 1.715 ± 0.039	3.956GlyAsn: 3.956 ± 0.085	1.905GlyPro: 1.905 ± 0.037	2.247GlyGln: 2.247 ± 0.041	2.471GlyArg: 2.471 ± 0.049	4.427GlySer: 4.427 ± 0.077	4.421GlyThr: 4.421 ± 0.109	4.48GlyVal: 4.48 ± 0.06	0.95GlyTrp: 0.95 ± 0.029	3.226GlyTyr: 3.226 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	1.205HisAla: 1.205 ± 0.034	0.2HisCys: 0.2 ± 0.012	1.031HisAsp: 1.031 ± 0.029	0.986HisGlu: 0.986 ± 0.031	1.211HisPhe: 1.211 ± 0.027	1.18HisGly: 1.18 ± 0.032	0.565HisHis: 0.565 ± 0.023	1.472HisIle: 1.472 ± 0.035	1.071HisLys: 1.071 ± 0.031	1.975HisLeu: 1.975 ± 0.041	0.402HisMet: 0.402 ± 0.017	0.938HisAsn: 0.938 ± 0.024	1.065HisPro: 1.065 ± 0.028	0.794HisGln: 0.794 ± 0.023	0.74HisArg: 0.74 ± 0.023	1.129HisSer: 1.129 ± 0.026	0.986HisThr: 0.986 ± 0.029	0.981HisVal: 0.981 ± 0.028	0.269HisTrp: 0.269 ± 0.014	0.898HisTyr: 0.898 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.245IleAla: 6.245 ± 0.076	0.768IleCys: 0.768 ± 0.027	4.253IleAsp: 4.253 ± 0.059	3.983IleGlu: 3.983 ± 0.066	3.401IlePhe: 3.401 ± 0.057	4.918IleGly: 4.918 ± 0.061	1.339IleHis: 1.339 ± 0.035	5.409IleIle: 5.409 ± 0.072	5.182IleLys: 5.182 ± 0.067	6.361IleLeu: 6.361 ± 0.085	1.404IleMet: 1.404 ± 0.034	4.531IleAsn: 4.531 ± 0.061	3.188IlePro: 3.188 ± 0.051	2.183IleGln: 2.183 ± 0.045	2.895IleArg: 2.895 ± 0.045	5.218IleSer: 5.218 ± 0.065	5.049IleThr: 5.049 ± 0.081	4.434IleVal: 4.434 ± 0.055	0.74IleTrp: 0.74 ± 0.026	2.728IleTyr: 2.728 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	5.243LysAla: 5.243 ± 0.07	0.347LysCys: 0.347 ± 0.016	3.784LysAsp: 3.784 ± 0.059	4.129LysGlu: 4.129 ± 0.073	2.637LysPhe: 2.637 ± 0.042	4.382LysGly: 4.382 ± 0.068	1.3LysHis: 1.3 ± 0.029	5.154LysIle: 5.154 ± 0.066	5.457LysLys: 5.457 ± 0.074	6.211LysLeu: 6.211 ± 0.071	1.841LysMet: 1.841 ± 0.034	4.246LysAsn: 4.246 ± 0.064	2.924LysPro: 2.924 ± 0.049	2.778LysGln: 2.778 ± 0.05	2.638LysArg: 2.638 ± 0.045	3.856LysSer: 3.856 ± 0.063	4.348LysThr: 4.348 ± 0.052	4.22LysVal: 4.22 ± 0.058	0.774LysTrp: 0.774 ± 0.022	2.914LysTyr: 2.914 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	7.089LeuAla: 7.089 ± 0.083	0.83LeuCys: 0.83 ± 0.027	4.535LeuAsp: 4.535 ± 0.057	4.301LeuGlu: 4.301 ± 0.076	4.9LeuPhe: 4.9 ± 0.079	5.713LeuGly: 5.713 ± 0.066	1.717LeuHis: 1.717 ± 0.035	6.748LeuIle: 6.748 ± 0.095	7.342LeuLys: 7.342 ± 0.079	9.36LeuLeu: 9.36 ± 0.113	2.204LeuMet: 2.204 ± 0.037	5.622LeuAsn: 5.622 ± 0.071	4.205LeuPro: 4.205 ± 0.058	3.496LeuGln: 3.496 ± 0.052	3.496LeuArg: 3.496 ± 0.048	6.664LeuSer: 6.664 ± 0.078	5.594LeuThr: 5.594 ± 0.063	5.806LeuVal: 5.806 ± 0.073	0.956LeuTrp: 0.956 ± 0.034	3.345LeuTyr: 3.345 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.033MetAla: 2.033 ± 0.041	0.148MetCys: 0.148 ± 0.011	1.252MetAsp: 1.252 ± 0.033	1.311MetGlu: 1.311 ± 0.039	0.828MetPhe: 0.828 ± 0.027	1.516MetGly: 1.516 ± 0.033	0.484MetHis: 0.484 ± 0.018	1.644MetIle: 1.644 ± 0.037	1.878MetLys: 1.878 ± 0.04	2.113MetLeu: 2.113 ± 0.048	0.607MetMet: 0.607 ± 0.02	1.238MetAsn: 1.238 ± 0.031	1.168MetPro: 1.168 ± 0.028	0.945MetGln: 0.945 ± 0.028	0.924MetArg: 0.924 ± 0.024	1.289MetSer: 1.289 ± 0.034	1.101MetThr: 1.101 ± 0.026	1.574MetVal: 1.574 ± 0.033	0.181MetTrp: 0.181 ± 0.009	0.636MetTyr: 0.636 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	4.085AsnAla: 4.085 ± 0.065	0.433AsnCys: 0.433 ± 0.019	2.974AsnAsp: 2.974 ± 0.051	2.911AsnGlu: 2.911 ± 0.051	2.703AsnPhe: 2.703 ± 0.048	4.394AsnGly: 4.394 ± 0.086	1.053AsnHis: 1.053 ± 0.032	4.375AsnIle: 4.375 ± 0.059	3.727AsnLys: 3.727 ± 0.057	5.047AsnLeu: 5.047 ± 0.068	1.231AsnMet: 1.231 ± 0.029	3.558AsnAsn: 3.558 ± 0.073	2.778AsnPro: 2.778 ± 0.049	1.977AsnGln: 1.977 ± 0.039	2.176AsnArg: 2.176 ± 0.042	3.451AsnSer: 3.451 ± 0.064	3.446AsnThr: 3.446 ± 0.074	3.21AsnVal: 3.21 ± 0.065	0.759AsnTrp: 0.759 ± 0.024	2.73AsnTyr: 2.73 ± 0.053	0.0AsnXaa: 0.0 ± 0.0
Pro	3.78ProAla: 3.78 ± 0.069	0.239ProCys: 0.239 ± 0.014	2.855ProAsp: 2.855 ± 0.047	2.748ProGlu: 2.748 ± 0.051	2.009ProPhe: 2.009 ± 0.035	3.361ProGly: 3.361 ± 0.057	0.73ProHis: 0.73 ± 0.025	2.34ProIle: 2.34 ± 0.04	2.21ProLys: 2.21 ± 0.035	3.401ProLeu: 3.401 ± 0.049	0.766ProMet: 0.766 ± 0.025	1.972ProAsn: 1.972 ± 0.045	1.289ProPro: 1.289 ± 0.039	1.396ProGln: 1.396 ± 0.035	1.105ProArg: 1.105 ± 0.027	2.274ProSer: 2.274 ± 0.055	1.94ProThr: 1.94 ± 0.045	3.675ProVal: 3.675 ± 0.06	0.447ProTrp: 0.447 ± 0.021	1.617ProTyr: 1.617 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.534GlnAla: 2.534 ± 0.047	0.228GlnCys: 0.228 ± 0.011	1.568GlnAsp: 1.568 ± 0.033	1.631GlnGlu: 1.631 ± 0.038	1.667GlnPhe: 1.667 ± 0.031	1.931GlnGly: 1.931 ± 0.045	0.76GlnHis: 0.76 ± 0.021	2.359GlnIle: 2.359 ± 0.043	2.542GlnLys: 2.542 ± 0.045	3.818GlnLeu: 3.818 ± 0.054	0.926GlnMet: 0.926 ± 0.023	2.167GlnAsn: 2.167 ± 0.05	1.492GlnPro: 1.492 ± 0.037	1.944GlnGln: 1.944 ± 0.044	1.388GlnArg: 1.388 ± 0.033	2.111GlnSer: 2.111 ± 0.039	2.141GlnThr: 2.141 ± 0.037	2.404GlnVal: 2.404 ± 0.044	0.445GlnTrp: 0.445 ± 0.02	1.567GlnTyr: 1.567 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.434ArgAla: 2.434 ± 0.046	0.248ArgCys: 0.248 ± 0.013	1.952ArgAsp: 1.952 ± 0.036	2.074ArgGlu: 2.074 ± 0.048	1.989ArgPhe: 1.989 ± 0.036	2.123ArgGly: 2.123 ± 0.045	0.76ArgHis: 0.76 ± 0.021	2.907ArgIle: 2.907 ± 0.047	2.664ArgLys: 2.664 ± 0.044	3.718ArgLeu: 3.718 ± 0.053	1.018ArgMet: 1.018 ± 0.027	2.015ArgAsn: 2.015 ± 0.04	1.368ArgPro: 1.368 ± 0.034	1.455ArgGln: 1.455 ± 0.032	1.56ArgArg: 1.56 ± 0.036	2.192ArgSer: 2.192 ± 0.038	1.85ArgThr: 1.85 ± 0.037	2.371ArgVal: 2.371 ± 0.042	0.495ArgTrp: 0.495 ± 0.02	1.733ArgTyr: 1.733 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.023SerAla: 5.023 ± 0.068	0.574SerCys: 0.574 ± 0.02	3.043SerAsp: 3.043 ± 0.05	2.689SerGlu: 2.689 ± 0.047	3.529SerPhe: 3.529 ± 0.055	5.259SerGly: 5.259 ± 0.096	1.136SerHis: 1.136 ± 0.029	4.708SerIle: 4.708 ± 0.063	3.629SerLys: 3.629 ± 0.056	6.005SerLeu: 6.005 ± 0.078	1.282SerMet: 1.282 ± 0.029	3.161SerAsn: 3.161 ± 0.063	2.687SerPro: 2.687 ± 0.049	1.997SerGln: 1.997 ± 0.039	2.258SerArg: 2.258 ± 0.044	4.0SerSer: 4.0 ± 0.069	3.665SerThr: 3.665 ± 0.065	4.244SerVal: 4.244 ± 0.069	0.715SerTrp: 0.715 ± 0.025	2.635SerTyr: 2.635 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	4.962ThrAla: 4.962 ± 0.085	0.435ThrCys: 0.435 ± 0.018	3.385ThrAsp: 3.385 ± 0.049	2.716ThrGlu: 2.716 ± 0.049	2.841ThrPhe: 2.841 ± 0.046	5.289ThrGly: 5.289 ± 0.082	1.069ThrHis: 1.069 ± 0.03	4.641ThrIle: 4.641 ± 0.076	3.027ThrLys: 3.027 ± 0.052	5.488ThrLeu: 5.488 ± 0.065	1.033ThrMet: 1.033 ± 0.027	3.004ThrAsn: 3.004 ± 0.065	2.799ThrPro: 2.799 ± 0.065	1.871ThrGln: 1.871 ± 0.035	1.977ThrArg: 1.977 ± 0.04	3.61ThrSer: 3.61 ± 0.065	3.738ThrThr: 3.738 ± 0.094	4.158ThrVal: 4.158 ± 0.09	0.697ThrTrp: 0.697 ± 0.023	2.516ThrTyr: 2.516 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	4.75ValAla: 4.75 ± 0.079	0.648ValCys: 0.648 ± 0.023	3.344ValAsp: 3.344 ± 0.046	3.136ValGlu: 3.136 ± 0.052	3.353ValPhe: 3.353 ± 0.056	3.681ValGly: 3.681 ± 0.059	1.077ValHis: 1.077 ± 0.027	5.069ValIle: 5.069 ± 0.058	4.679ValLys: 4.679 ± 0.071	5.933ValLeu: 5.933 ± 0.072	1.413ValMet: 1.413 ± 0.036	3.937ValAsn: 3.937 ± 0.066	2.485ValPro: 2.485 ± 0.044	1.975ValGln: 1.975 ± 0.039	2.132ValArg: 2.132 ± 0.04	4.415ValSer: 4.415 ± 0.067	4.203ValThr: 4.203 ± 0.087	4.129ValVal: 4.129 ± 0.056	0.684ValTrp: 0.684 ± 0.026	2.704ValTyr: 2.704 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.794TrpAla: 0.794 ± 0.028	0.128TrpCys: 0.128 ± 0.01	0.67TrpAsp: 0.67 ± 0.022	0.591TrpGlu: 0.591 ± 0.02	0.636TrpPhe: 0.636 ± 0.024	0.838TrpGly: 0.838 ± 0.029	0.266TrpHis: 0.266 ± 0.015	0.763TrpIle: 0.763 ± 0.024	0.811TrpLys: 0.811 ± 0.027	1.231TrpLeu: 1.231 ± 0.03	0.377TrpMet: 0.377 ± 0.018	0.645TrpAsn: 0.645 ± 0.02	0.389TrpPro: 0.389 ± 0.017	0.541TrpGln: 0.541 ± 0.021	0.516TrpArg: 0.516 ± 0.022	0.674TrpSer: 0.674 ± 0.021	0.579TrpThr: 0.579 ± 0.023	0.735TrpVal: 0.735 ± 0.026	0.226TrpTrp: 0.226 ± 0.015	0.474TrpTyr: 0.474 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.912TyrAla: 2.912 ± 0.048	0.408TyrCys: 0.408 ± 0.018	2.319TyrAsp: 2.319 ± 0.044	1.856TyrGlu: 1.856 ± 0.038	2.335TyrPhe: 2.335 ± 0.045	2.809TyrGly: 2.809 ± 0.06	0.997TyrHis: 0.997 ± 0.026	2.64TyrIle: 2.64 ± 0.044	2.789TyrLys: 2.789 ± 0.044	4.02TyrLeu: 4.02 ± 0.06	0.808TyrMet: 0.808 ± 0.023	2.555TyrAsn: 2.555 ± 0.055	1.763TyrPro: 1.763 ± 0.045	1.649TyrGln: 1.649 ± 0.035	1.799TyrArg: 1.799 ± 0.038	2.778TyrSer: 2.778 ± 0.055	2.673TyrThr: 2.673 ± 0.058	2.239TyrVal: 2.239 ± 0.044	0.531TyrTrp: 0.531 ± 0.02	2.011TyrTyr: 2.011 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4446 proteins (1441222 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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