Amino acid dipepetide frequency for Pacific flying fox faeces associated circular DNA virus-10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.942AlaAla: 4.942 ± 3.314
0.0AlaCys: 0.0 ± 0.0
1.647AlaAsp: 1.647 ± 1.105
1.647AlaGlu: 1.647 ± 1.105
4.942AlaPhe: 4.942 ± 0.798
0.0AlaGly: 0.0 ± 0.0
1.647AlaHis: 1.647 ± 1.411
4.942AlaIle: 4.942 ± 0.798
3.295AlaLys: 3.295 ± 0.307
3.295AlaLeu: 3.295 ± 2.209
0.0AlaMet: 0.0 ± 0.0
3.295AlaAsn: 3.295 ± 0.307
3.295AlaPro: 3.295 ± 2.209
3.295AlaGln: 3.295 ± 2.209
8.237AlaArg: 8.237 ± 0.491
4.942AlaSer: 4.942 ± 0.798
3.295AlaThr: 3.295 ± 2.823
6.59AlaVal: 6.59 ± 4.419
0.0AlaTrp: 0.0 ± 0.0
3.295AlaTyr: 3.295 ± 0.307
0.0AlaXaa: 0.0 ± 0.0
Cys
1.647CysAla: 1.647 ± 1.105
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.647CysGlu: 1.647 ± 1.411
1.647CysPhe: 1.647 ± 1.411
3.295CysGly: 3.295 ± 0.307
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.647CysLys: 1.647 ± 1.411
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
3.295CysPro: 3.295 ± 0.307
1.647CysGln: 1.647 ± 1.411
0.0CysArg: 0.0 ± 0.0
4.942CysSer: 4.942 ± 0.798
1.647CysThr: 1.647 ± 1.105
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.295AspAla: 3.295 ± 2.209
1.647AspCys: 1.647 ± 1.105
1.647AspAsp: 1.647 ± 1.411
0.0AspGlu: 0.0 ± 0.0
3.295AspPhe: 3.295 ± 0.307
3.295AspGly: 3.295 ± 2.823
0.0AspHis: 0.0 ± 0.0
4.942AspIle: 4.942 ± 0.798
1.647AspLys: 1.647 ± 1.411
4.942AspLeu: 4.942 ± 0.798
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
3.295AspPro: 3.295 ± 0.307
1.647AspGln: 1.647 ± 1.105
0.0AspArg: 0.0 ± 0.0
3.295AspSer: 3.295 ± 0.307
3.295AspThr: 3.295 ± 2.209
0.0AspVal: 0.0 ± 0.0
0.0AspTrp: 0.0 ± 0.0
1.647AspTyr: 1.647 ± 1.105
0.0AspXaa: 0.0 ± 0.0
Glu
3.295GluAla: 3.295 ± 2.823
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
3.295GluGlu: 3.295 ± 2.823
1.647GluPhe: 1.647 ± 1.105
0.0GluGly: 0.0 ± 0.0
1.647GluHis: 1.647 ± 1.411
0.0GluIle: 0.0 ± 0.0
3.295GluLys: 3.295 ± 2.823
1.647GluLeu: 1.647 ± 1.411
0.0GluMet: 0.0 ± 0.0
3.295GluAsn: 3.295 ± 2.209
3.295GluPro: 3.295 ± 2.823
6.59GluGln: 6.59 ± 0.613
3.295GluArg: 3.295 ± 0.307
1.647GluSer: 1.647 ± 1.105
8.237GluThr: 8.237 ± 2.025
3.295GluVal: 3.295 ± 2.209
1.647GluTrp: 1.647 ± 1.411
3.295GluTyr: 3.295 ± 0.307
0.0GluXaa: 0.0 ± 0.0
Phe
3.295PheAla: 3.295 ± 0.307
1.647PheCys: 1.647 ± 1.105
4.942PheAsp: 4.942 ± 0.798
0.0PheGlu: 0.0 ± 0.0
1.647PhePhe: 1.647 ± 1.105
3.295PheGly: 3.295 ± 2.209
0.0PheHis: 0.0 ± 0.0
3.295PheIle: 3.295 ± 2.823
6.59PheLys: 6.59 ± 3.129
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
4.942PheGln: 4.942 ± 0.798
0.0PheArg: 0.0 ± 0.0
3.295PheSer: 3.295 ± 2.209
4.942PheThr: 4.942 ± 0.798
4.942PheVal: 4.942 ± 1.718
0.0PheTrp: 0.0 ± 0.0
3.295PheTyr: 3.295 ± 2.823
0.0PheXaa: 0.0 ± 0.0
Gly
3.295GlyAla: 3.295 ± 0.307
0.0GlyCys: 0.0 ± 0.0
1.647GlyAsp: 1.647 ± 1.411
1.647GlyGlu: 1.647 ± 1.411
1.647GlyPhe: 1.647 ± 1.105
3.295GlyGly: 3.295 ± 2.823
1.647GlyHis: 1.647 ± 1.411
3.295GlyIle: 3.295 ± 0.307
1.647GlyLys: 1.647 ± 1.411
1.647GlyLeu: 1.647 ± 1.411
0.0GlyMet: 0.0 ± 0.0
1.647GlyAsn: 1.647 ± 1.411
1.647GlyPro: 1.647 ± 1.105
3.295GlyGln: 3.295 ± 0.307
6.59GlyArg: 6.59 ± 1.903
3.295GlySer: 3.295 ± 0.307
8.237GlyThr: 8.237 ± 0.491
6.59GlyVal: 6.59 ± 3.129
1.647GlyTrp: 1.647 ± 1.411
1.647GlyTyr: 1.647 ± 1.411
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
3.295HisCys: 3.295 ± 0.307
0.0HisAsp: 0.0 ± 0.0
1.647HisGlu: 1.647 ± 1.411
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.647HisIle: 1.647 ± 1.411
0.0HisLys: 0.0 ± 0.0
1.647HisLeu: 1.647 ± 1.105
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.295HisPro: 3.295 ± 2.823
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.647HisVal: 1.647 ± 1.105
1.647HisTrp: 1.647 ± 1.411
1.647HisTyr: 1.647 ± 1.411
0.0HisXaa: 0.0 ± 0.0
Ile
3.295IleAla: 3.295 ± 2.209
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
4.942IleGlu: 4.942 ± 1.718
3.295IlePhe: 3.295 ± 2.823
1.647IleGly: 1.647 ± 1.411
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
6.59IleLys: 6.59 ± 3.129
3.295IleLeu: 3.295 ± 2.823
0.0IleMet: 0.0 ± 0.0
1.647IleAsn: 1.647 ± 1.411
1.647IlePro: 1.647 ± 1.105
3.295IleGln: 3.295 ± 0.307
3.295IleArg: 3.295 ± 2.209
4.942IleSer: 4.942 ± 0.798
1.647IleThr: 1.647 ± 1.105
1.647IleVal: 1.647 ± 1.105
1.647IleTrp: 1.647 ± 1.105
1.647IleTyr: 1.647 ± 1.411
0.0IleXaa: 0.0 ± 0.0
Lys
3.295LysAla: 3.295 ± 0.307
1.647LysCys: 1.647 ± 1.105
1.647LysAsp: 1.647 ± 1.411
4.942LysGlu: 4.942 ± 1.718
1.647LysPhe: 1.647 ± 1.411
1.647LysGly: 1.647 ± 1.411
1.647LysHis: 1.647 ± 1.411
1.647LysIle: 1.647 ± 1.105
1.647LysLys: 1.647 ± 1.411
4.942LysLeu: 4.942 ± 0.798
0.0LysMet: 0.0 ± 0.0
3.295LysAsn: 3.295 ± 0.307
1.647LysPro: 1.647 ± 1.411
1.647LysGln: 1.647 ± 1.411
4.942LysArg: 4.942 ± 0.798
6.59LysSer: 6.59 ± 3.129
3.295LysThr: 3.295 ± 2.209
1.647LysVal: 1.647 ± 1.411
0.0LysTrp: 0.0 ± 0.0
6.59LysTyr: 6.59 ± 0.613
0.0LysXaa: 0.0 ± 0.0
Leu
3.295LeuAla: 3.295 ± 2.209
0.0LeuCys: 0.0 ± 0.0
3.295LeuAsp: 3.295 ± 2.823
3.295LeuGlu: 3.295 ± 2.823
1.647LeuPhe: 1.647 ± 1.105
8.237LeuGly: 8.237 ± 2.025
3.295LeuHis: 3.295 ± 0.307
1.647LeuIle: 1.647 ± 1.105
4.942LeuLys: 4.942 ± 0.798
4.942LeuLeu: 4.942 ± 0.798
0.0LeuMet: 0.0 ± 0.0
3.295LeuAsn: 3.295 ± 2.823
4.942LeuPro: 4.942 ± 0.798
0.0LeuGln: 0.0 ± 0.0
3.295LeuArg: 3.295 ± 0.307
1.647LeuSer: 1.647 ± 1.105
3.295LeuThr: 3.295 ± 0.307
1.647LeuVal: 1.647 ± 1.105
4.942LeuTrp: 4.942 ± 1.718
1.647LeuTyr: 1.647 ± 1.105
0.0LeuXaa: 0.0 ± 0.0
Met
1.647MetAla: 1.647 ± 1.105
0.0MetCys: 0.0 ± 0.0
1.647MetAsp: 1.647 ± 1.105
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.647MetLeu: 1.647 ± 1.411
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.647MetArg: 1.647 ± 1.105
1.647MetSer: 1.647 ± 1.411
0.0MetThr: 0.0 ± 0.0
3.295MetVal: 3.295 ± 0.307
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.647AsnAla: 1.647 ± 1.411
0.0AsnCys: 0.0 ± 0.0
1.647AsnAsp: 1.647 ± 1.411
1.647AsnGlu: 1.647 ± 1.411
0.0AsnPhe: 0.0 ± 0.0
1.647AsnGly: 1.647 ± 1.411
0.0AsnHis: 0.0 ± 0.0
3.295AsnIle: 3.295 ± 0.307
4.942AsnLys: 4.942 ± 0.798
3.295AsnLeu: 3.295 ± 2.209
0.0AsnMet: 0.0 ± 0.0
1.647AsnAsn: 1.647 ± 1.105
3.295AsnPro: 3.295 ± 2.209
1.647AsnGln: 1.647 ± 1.411
0.0AsnArg: 0.0 ± 0.0
3.295AsnSer: 3.295 ± 0.307
0.0AsnThr: 0.0 ± 0.0
0.0AsnVal: 0.0 ± 0.0
3.295AsnTrp: 3.295 ± 0.307
1.647AsnTyr: 1.647 ± 1.105
0.0AsnXaa: 0.0 ± 0.0
Pro
1.647ProAla: 1.647 ± 1.105
1.647ProCys: 1.647 ± 1.411
4.942ProAsp: 4.942 ± 3.314
1.647ProGlu: 1.647 ± 1.411
3.295ProPhe: 3.295 ± 2.209
4.942ProGly: 4.942 ± 4.234
0.0ProHis: 0.0 ± 0.0
3.295ProIle: 3.295 ± 2.823
1.647ProLys: 1.647 ± 1.105
3.295ProLeu: 3.295 ± 0.307
0.0ProMet: 0.0 ± 0.0
1.647ProAsn: 1.647 ± 1.105
6.59ProPro: 6.59 ± 4.419
3.295ProGln: 3.295 ± 0.307
1.647ProArg: 1.647 ± 1.105
3.295ProSer: 3.295 ± 0.307
6.59ProThr: 6.59 ± 1.903
3.295ProVal: 3.295 ± 2.209
1.647ProTrp: 1.647 ± 1.105
3.295ProTyr: 3.295 ± 0.307
0.0ProXaa: 0.0 ± 0.0
Gln
8.237GlnAla: 8.237 ± 2.025
3.295GlnCys: 3.295 ± 2.823
0.0GlnAsp: 0.0 ± 0.0
6.59GlnGlu: 6.59 ± 0.613
3.295GlnPhe: 3.295 ± 0.307
1.647GlnGly: 1.647 ± 1.411
1.647GlnHis: 1.647 ± 1.411
1.647GlnIle: 1.647 ± 1.105
3.295GlnLys: 3.295 ± 2.823
6.59GlnLeu: 6.59 ± 0.613
1.647GlnMet: 1.647 ± 1.105
1.647GlnAsn: 1.647 ± 1.411
4.942GlnPro: 4.942 ± 3.314
3.295GlnGln: 3.295 ± 0.307
3.295GlnArg: 3.295 ± 0.307
3.295GlnSer: 3.295 ± 2.209
1.647GlnThr: 1.647 ± 1.411
3.295GlnVal: 3.295 ± 0.307
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
1.647ArgAsp: 1.647 ± 1.105
0.0ArgGlu: 0.0 ± 0.0
3.295ArgPhe: 3.295 ± 0.307
3.295ArgGly: 3.295 ± 2.209
0.0ArgHis: 0.0 ± 0.0
3.295ArgIle: 3.295 ± 2.823
4.942ArgLys: 4.942 ± 3.314
4.942ArgLeu: 4.942 ± 0.798
1.647ArgMet: 1.647 ± 1.105
1.647ArgAsn: 1.647 ± 1.105
1.647ArgPro: 1.647 ± 1.105
4.942ArgGln: 4.942 ± 4.234
28.007ArgArg: 28.007 ± 13.747
8.237ArgSer: 8.237 ± 3.007
0.0ArgThr: 0.0 ± 0.0
14.827ArgVal: 14.827 ± 2.394
6.59ArgTrp: 6.59 ± 0.613
1.647ArgTyr: 1.647 ± 1.105
0.0ArgXaa: 0.0 ± 0.0
Ser
6.59SerAla: 6.59 ± 0.613
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
3.295SerGlu: 3.295 ± 0.307
3.295SerPhe: 3.295 ± 0.307
8.237SerGly: 8.237 ± 3.007
1.647SerHis: 1.647 ± 1.411
0.0SerIle: 0.0 ± 0.0
1.647SerLys: 1.647 ± 1.105
8.237SerLeu: 8.237 ± 2.025
4.942SerMet: 4.942 ± 0.593
8.237SerAsn: 8.237 ± 3.007
0.0SerPro: 0.0 ± 0.0
1.647SerGln: 1.647 ± 1.411
6.59SerArg: 6.59 ± 1.903
6.59SerSer: 6.59 ± 4.419
3.295SerThr: 3.295 ± 2.209
9.885SerVal: 9.885 ± 1.596
3.295SerTrp: 3.295 ± 2.209
1.647SerTyr: 1.647 ± 1.411
0.0SerXaa: 0.0 ± 0.0
Thr
4.942ThrAla: 4.942 ± 3.314
1.647ThrCys: 1.647 ± 1.105
6.59ThrAsp: 6.59 ± 1.903
6.59ThrGlu: 6.59 ± 1.903
3.295ThrPhe: 3.295 ± 0.307
3.295ThrGly: 3.295 ± 2.823
0.0ThrHis: 0.0 ± 0.0
3.295ThrIle: 3.295 ± 2.823
0.0ThrLys: 0.0 ± 0.0
1.647ThrLeu: 1.647 ± 1.411
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
4.942ThrPro: 4.942 ± 0.798
3.295ThrGln: 3.295 ± 2.209
4.942ThrArg: 4.942 ± 4.234
9.885ThrSer: 9.885 ± 1.596
6.59ThrThr: 6.59 ± 0.613
4.942ThrVal: 4.942 ± 0.798
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.295ValAla: 3.295 ± 2.209
1.647ValCys: 1.647 ± 1.105
1.647ValAsp: 1.647 ± 1.105
4.942ValGlu: 4.942 ± 3.314
6.59ValPhe: 6.59 ± 0.613
0.0ValGly: 0.0 ± 0.0
1.647ValHis: 1.647 ± 1.105
8.237ValIle: 8.237 ± 3.007
4.942ValLys: 4.942 ± 1.718
1.647ValLeu: 1.647 ± 1.105
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
6.59ValPro: 6.59 ± 0.613
6.59ValGln: 6.59 ± 1.903
9.885ValArg: 9.885 ± 4.112
0.0ValSer: 0.0 ± 0.0
4.942ValThr: 4.942 ± 1.718
8.237ValVal: 8.237 ± 5.523
4.942ValTrp: 4.942 ± 4.234
3.295ValTyr: 3.295 ± 0.307
0.0ValXaa: 0.0 ± 0.0
Trp
3.295TrpAla: 3.295 ± 2.209
1.647TrpCys: 1.647 ± 1.411
1.647TrpAsp: 1.647 ± 1.411
1.647TrpGlu: 1.647 ± 1.411
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.647TrpLys: 1.647 ± 1.105
1.647TrpLeu: 1.647 ± 1.411
1.647TrpMet: 1.647 ± 2.185
0.0TrpAsn: 0.0 ± 0.0
1.647TrpPro: 1.647 ± 1.411
4.942TrpGln: 4.942 ± 1.718
1.647TrpArg: 1.647 ± 1.105
1.647TrpSer: 1.647 ± 1.105
3.295TrpThr: 3.295 ± 0.307
1.647TrpVal: 1.647 ± 1.411
6.59TrpTrp: 6.59 ± 3.129
1.647TrpTyr: 1.647 ± 1.105
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.647TyrAla: 1.647 ± 1.105
3.295TyrCys: 3.295 ± 2.823
3.295TyrAsp: 3.295 ± 2.209
0.0TyrGlu: 0.0 ± 0.0
1.647TyrPhe: 1.647 ± 1.411
6.59TyrGly: 6.59 ± 0.613
1.647TyrHis: 1.647 ± 1.105
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.647TyrAsn: 1.647 ± 1.411
1.647TyrPro: 1.647 ± 1.105
3.295TyrGln: 3.295 ± 2.823
3.295TyrArg: 3.295 ± 0.307
6.59TyrSer: 6.59 ± 0.613
1.647TyrThr: 1.647 ± 1.411
1.647TyrVal: 1.647 ± 1.105
0.0TyrTrp: 0.0 ± 0.0
3.295TyrTyr: 3.295 ± 2.209
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (608 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski