Amino acid dipepetide frequency for Campylobacter mucosalis CCUG 21559

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.801AlaAla: 3.801 ± 0.118
0.881AlaCys: 0.881 ± 0.043
3.856AlaAsp: 3.856 ± 0.091
3.074AlaGlu: 3.074 ± 0.084
3.664AlaPhe: 3.664 ± 0.094
4.299AlaGly: 4.299 ± 0.111
1.134AlaHis: 1.134 ± 0.048
6.62AlaIle: 6.62 ± 0.13
8.112AlaLys: 8.112 ± 0.137
8.08AlaLeu: 8.08 ± 0.145
2.131AlaMet: 2.131 ± 0.063
4.892AlaAsn: 4.892 ± 0.123
1.806AlaPro: 1.806 ± 0.065
2.599AlaGln: 2.599 ± 0.08
2.762AlaArg: 2.762 ± 0.076
4.484AlaSer: 4.484 ± 0.098
3.808AlaThr: 3.808 ± 0.091
4.869AlaVal: 4.869 ± 0.097
0.453AlaTrp: 0.453 ± 0.028
2.501AlaTyr: 2.501 ± 0.062
0.0AlaXaa: 0.0 ± 0.0
Cys
0.79CysAla: 0.79 ± 0.04
0.119CysCys: 0.119 ± 0.018
0.808CysAsp: 0.808 ± 0.038
0.952CysGlu: 0.952 ± 0.041
0.558CysPhe: 0.558 ± 0.032
0.961CysGly: 0.961 ± 0.045
0.255CysHis: 0.255 ± 0.03
0.834CysIle: 0.834 ± 0.039
0.813CysLys: 0.813 ± 0.038
0.85CysLeu: 0.85 ± 0.041
0.259CysMet: 0.259 ± 0.021
0.362CysAsn: 0.362 ± 0.024
0.317CysPro: 0.317 ± 0.026
0.244CysGln: 0.244 ± 0.02
0.239CysArg: 0.239 ± 0.022
0.603CysSer: 0.603 ± 0.035
0.362CysThr: 0.362 ± 0.027
1.055CysVal: 1.055 ± 0.048
0.068CysTrp: 0.068 ± 0.012
0.385CysTyr: 0.385 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
3.905AspAla: 3.905 ± 0.103
0.483AspCys: 0.483 ± 0.028
4.165AspAsp: 4.165 ± 0.112
6.663AspGlu: 6.663 ± 0.127
3.528AspPhe: 3.528 ± 0.078
3.676AspGly: 3.676 ± 0.119
0.544AspHis: 0.544 ± 0.036
5.541AspIle: 5.541 ± 0.104
5.215AspLys: 5.215 ± 0.106
4.529AspLeu: 4.529 ± 0.088
1.455AspMet: 1.455 ± 0.055
2.555AspAsn: 2.555 ± 0.082
1.337AspPro: 1.337 ± 0.055
0.893AspGln: 0.893 ± 0.046
1.81AspArg: 1.81 ± 0.07
3.197AspSer: 3.197 ± 0.078
2.929AspThr: 2.929 ± 0.094
3.739AspVal: 3.739 ± 0.098
0.292AspTrp: 0.292 ± 0.023
1.879AspTyr: 1.879 ± 0.059
0.0AspXaa: 0.0 ± 0.0
Glu
4.616GluAla: 4.616 ± 0.104
0.806GluCys: 0.806 ± 0.037
2.14GluAsp: 2.14 ± 0.062
2.548GluGlu: 2.548 ± 0.083
4.013GluPhe: 4.013 ± 0.085
2.496GluGly: 2.496 ± 0.073
1.013GluHis: 1.013 ± 0.046
7.499GluIle: 7.499 ± 0.117
4.841GluLys: 4.841 ± 0.104
8.214GluLeu: 8.214 ± 0.147
1.291GluMet: 1.291 ± 0.049
4.809GluAsn: 4.809 ± 0.094
1.844GluPro: 1.844 ± 0.056
2.694GluGln: 2.694 ± 0.081
2.728GluArg: 2.728 ± 0.074
3.245GluSer: 3.245 ± 0.078
1.881GluThr: 1.881 ± 0.064
3.58GluVal: 3.58 ± 0.084
0.476GluTrp: 0.476 ± 0.029
2.482GluTyr: 2.482 ± 0.075
0.0GluXaa: 0.0 ± 0.0
Phe
3.89PheAla: 3.89 ± 0.099
0.818PheCys: 0.818 ± 0.041
3.662PheAsp: 3.662 ± 0.09
3.334PheGlu: 3.334 ± 0.084
2.967PhePhe: 2.967 ± 0.098
4.168PheGly: 4.168 ± 0.107
0.576PheHis: 0.576 ± 0.035
4.743PheIle: 4.743 ± 0.112
4.76PheLys: 4.76 ± 0.107
5.705PheLeu: 5.705 ± 0.134
1.412PheMet: 1.412 ± 0.057
2.881PheAsn: 2.881 ± 0.072
0.808PhePro: 0.808 ± 0.039
0.767PheGln: 0.767 ± 0.034
1.585PheArg: 1.585 ± 0.051
4.577PheSer: 4.577 ± 0.108
2.28PheThr: 2.28 ± 0.066
3.571PheVal: 3.571 ± 0.097
0.471PheTrp: 0.471 ± 0.032
2.352PheTyr: 2.352 ± 0.076
0.0PheXaa: 0.0 ± 0.0
Gly
4.923GlyAla: 4.923 ± 0.109
0.804GlyCys: 0.804 ± 0.041
3.473GlyAsp: 3.473 ± 0.093
3.915GlyGlu: 3.915 ± 0.096
3.956GlyPhe: 3.956 ± 0.092
4.404GlyGly: 4.404 ± 0.106
0.922GlyHis: 0.922 ± 0.04
5.247GlyIle: 5.247 ± 0.109
4.791GlyLys: 4.791 ± 0.102
5.711GlyLeu: 5.711 ± 0.109
1.417GlyMet: 1.417 ± 0.054
2.412GlyAsn: 2.412 ± 0.092
0.711GlyPro: 0.711 ± 0.039
1.314GlyGln: 1.314 ± 0.051
2.049GlyArg: 2.049 ± 0.058
3.862GlySer: 3.862 ± 0.093
2.721GlyThr: 2.721 ± 0.091
5.771GlyVal: 5.771 ± 0.121
0.481GlyTrp: 0.481 ± 0.031
2.674GlyTyr: 2.674 ± 0.067
0.0GlyXaa: 0.0 ± 0.0
His
1.013HisAla: 1.013 ± 0.043
0.187HisCys: 0.187 ± 0.017
0.702HisAsp: 0.702 ± 0.036
0.781HisGlu: 0.781 ± 0.032
0.904HisPhe: 0.904 ± 0.041
0.856HisGly: 0.856 ± 0.042
0.307HisHis: 0.307 ± 0.027
1.344HisIle: 1.344 ± 0.048
1.25HisLys: 1.25 ± 0.044
1.392HisLeu: 1.392 ± 0.053
0.283HisMet: 0.283 ± 0.024
0.722HisAsn: 0.722 ± 0.034
0.626HisPro: 0.626 ± 0.04
0.448HisGln: 0.448 ± 0.027
0.489HisArg: 0.489 ± 0.032
0.99HisSer: 0.99 ± 0.045
0.817HisThr: 0.817 ± 0.041
0.665HisVal: 0.665 ± 0.031
0.096HisTrp: 0.096 ± 0.014
0.587HisTyr: 0.587 ± 0.028
0.0HisXaa: 0.0 ± 0.0
Ile
6.652IleAla: 6.652 ± 0.117
1.214IleCys: 1.214 ± 0.047
5.47IleAsp: 5.47 ± 0.102
4.837IleGlu: 4.837 ± 0.108
4.917IlePhe: 4.917 ± 0.129
5.01IleGly: 5.01 ± 0.091
0.99IleHis: 0.99 ± 0.041
5.989IleIle: 5.989 ± 0.126
8.109IleLys: 8.109 ± 0.155
8.957IleLeu: 8.957 ± 0.139
1.617IleMet: 1.617 ± 0.055
5.55IleAsn: 5.55 ± 0.13
2.093IlePro: 2.093 ± 0.077
1.799IleGln: 1.799 ± 0.053
2.575IleArg: 2.575 ± 0.073
6.805IleSer: 6.805 ± 0.123
4.144IleThr: 4.144 ± 0.102
5.103IleVal: 5.103 ± 0.109
0.53IleTrp: 0.53 ± 0.032
3.209IleTyr: 3.209 ± 0.091
0.0IleXaa: 0.0 ± 0.0
Lys
6.121LysAla: 6.121 ± 0.118
0.615LysCys: 0.615 ± 0.035
6.123LysAsp: 6.123 ± 0.105
6.47LysGlu: 6.47 ± 0.131
5.475LysPhe: 5.475 ± 0.097
4.076LysGly: 4.076 ± 0.086
1.255LysHis: 1.255 ± 0.04
8.469LysIle: 8.469 ± 0.143
6.673LysLys: 6.673 ± 0.137
6.517LysLeu: 6.517 ± 0.118
2.33LysMet: 2.33 ± 0.06
7.237LysAsn: 7.237 ± 0.155
2.68LysPro: 2.68 ± 0.075
2.977LysGln: 2.977 ± 0.073
3.363LysArg: 3.363 ± 0.079
5.671LysSer: 5.671 ± 0.096
4.489LysThr: 4.489 ± 0.105
4.161LysVal: 4.161 ± 0.114
0.49LysTrp: 0.49 ± 0.031
2.476LysTyr: 2.476 ± 0.077
0.0LysXaa: 0.0 ± 0.0
Leu
7.574LeuAla: 7.574 ± 0.126
1.162LeuCys: 1.162 ± 0.05
5.411LeuAsp: 5.411 ± 0.112
6.098LeuGlu: 6.098 ± 0.111
4.796LeuPhe: 4.796 ± 0.119
6.501LeuGly: 6.501 ± 0.133
1.294LeuHis: 1.294 ± 0.047
6.882LeuIle: 6.882 ± 0.12
10.357LeuLys: 10.357 ± 0.158
8.403LeuLeu: 8.403 ± 0.172
2.088LeuMet: 2.088 ± 0.064
7.125LeuAsn: 7.125 ± 0.156
3.117LeuPro: 3.117 ± 0.074
2.343LeuGln: 2.343 ± 0.069
3.386LeuArg: 3.386 ± 0.085
8.191LeuSer: 8.191 ± 0.156
4.291LeuThr: 4.291 ± 0.093
5.424LeuVal: 5.424 ± 0.11
0.587LeuTrp: 0.587 ± 0.037
2.846LeuTyr: 2.846 ± 0.078
0.0LeuXaa: 0.0 ± 0.0
Met
1.99MetAla: 1.99 ± 0.062
0.219MetCys: 0.219 ± 0.02
1.157MetAsp: 1.157 ± 0.049
0.779MetGlu: 0.779 ± 0.039
1.075MetPhe: 1.075 ± 0.049
1.521MetGly: 1.521 ± 0.053
0.382MetHis: 0.382 ± 0.021
1.992MetIle: 1.992 ± 0.061
1.949MetLys: 1.949 ± 0.054
2.437MetLeu: 2.437 ± 0.069
0.538MetMet: 0.538 ± 0.034
1.004MetAsn: 1.004 ± 0.039
1.052MetPro: 1.052 ± 0.042
1.114MetGln: 1.114 ± 0.048
1.031MetArg: 1.031 ± 0.042
1.901MetSer: 1.901 ± 0.057
0.822MetThr: 0.822 ± 0.04
1.22MetVal: 1.22 ± 0.047
0.141MetTrp: 0.141 ± 0.015
0.505MetTyr: 0.505 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
5.167AsnAla: 5.167 ± 0.121
0.419AsnCys: 0.419 ± 0.025
3.357AsnAsp: 3.357 ± 0.091
4.855AsnGlu: 4.855 ± 0.096
3.641AsnPhe: 3.641 ± 0.11
4.067AsnGly: 4.067 ± 0.12
0.758AsnHis: 0.758 ± 0.034
4.983AsnIle: 4.983 ± 0.126
3.969AsnLys: 3.969 ± 0.113
7.028AsnLeu: 7.028 ± 0.137
1.091AsnMet: 1.091 ± 0.042
2.498AsnAsn: 2.498 ± 0.115
2.075AsnPro: 2.075 ± 0.063
1.701AsnGln: 1.701 ± 0.058
1.902AsnArg: 1.902 ± 0.06
4.012AsnSer: 4.012 ± 0.101
2.981AsnThr: 2.981 ± 0.102
3.322AsnVal: 3.322 ± 0.079
0.269AsnTrp: 0.269 ± 0.022
1.906AsnTyr: 1.906 ± 0.057
0.0AsnXaa: 0.0 ± 0.0
Pro
1.701ProAla: 1.701 ± 0.061
0.266ProCys: 0.266 ± 0.02
1.385ProAsp: 1.385 ± 0.05
1.672ProGlu: 1.672 ± 0.065
1.733ProPhe: 1.733 ± 0.054
1.234ProGly: 1.234 ± 0.056
0.558ProHis: 0.558 ± 0.026
2.25ProIle: 2.25 ± 0.063
2.671ProLys: 2.671 ± 0.08
2.669ProLeu: 2.669 ± 0.078
0.583ProMet: 0.583 ± 0.031
1.97ProAsn: 1.97 ± 0.064
0.726ProPro: 0.726 ± 0.038
0.925ProGln: 0.925 ± 0.044
0.861ProArg: 0.861 ± 0.039
1.885ProSer: 1.885 ± 0.057
1.567ProThr: 1.567 ± 0.053
1.899ProVal: 1.899 ± 0.064
0.196ProTrp: 0.196 ± 0.017
1.125ProTyr: 1.125 ± 0.045
0.0ProXaa: 0.0 ± 0.0
Gln
1.886GlnAla: 1.886 ± 0.061
0.152GlnCys: 0.152 ± 0.016
1.517GlnAsp: 1.517 ± 0.053
1.628GlnGlu: 1.628 ± 0.064
0.924GlnPhe: 0.924 ± 0.041
1.544GlnGly: 1.544 ± 0.056
0.314GlnHis: 0.314 ± 0.025
3.261GlnIle: 3.261 ± 0.088
3.22GlnLys: 3.22 ± 0.082
1.781GlnLeu: 1.781 ± 0.052
0.815GlnMet: 0.815 ± 0.035
3.247GlnAsn: 3.247 ± 0.092
0.613GlnPro: 0.613 ± 0.032
0.626GlnGln: 0.626 ± 0.033
1.018GlnArg: 1.018 ± 0.043
2.148GlnSer: 2.148 ± 0.059
1.826GlnThr: 1.826 ± 0.06
1.332GlnVal: 1.332 ± 0.055
0.164GlnTrp: 0.164 ± 0.019
0.64GlnTyr: 0.64 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
2.979ArgAla: 2.979 ± 0.073
0.287ArgCys: 0.287 ± 0.023
2.041ArgAsp: 2.041 ± 0.066
2.534ArgGlu: 2.534 ± 0.076
1.829ArgPhe: 1.829 ± 0.068
1.92ArgGly: 1.92 ± 0.065
0.653ArgHis: 0.653 ± 0.033
2.778ArgIle: 2.778 ± 0.074
2.279ArgLys: 2.279 ± 0.067
3.858ArgLeu: 3.858 ± 0.077
0.795ArgMet: 0.795 ± 0.037
1.667ArgAsn: 1.667 ± 0.053
0.918ArgPro: 0.918 ± 0.043
1.134ArgGln: 1.134 ± 0.048
1.241ArgArg: 1.241 ± 0.057
1.911ArgSer: 1.911 ± 0.056
1.344ArgThr: 1.344 ± 0.056
2.596ArgVal: 2.596 ± 0.065
0.209ArgTrp: 0.209 ± 0.018
1.455ArgTyr: 1.455 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
4.666SerAla: 4.666 ± 0.101
0.674SerCys: 0.674 ± 0.035
4.265SerAsp: 4.265 ± 0.088
4.568SerGlu: 4.568 ± 0.087
3.623SerPhe: 3.623 ± 0.087
4.842SerGly: 4.842 ± 0.104
1.093SerHis: 1.093 ± 0.051
5.185SerIle: 5.185 ± 0.106
5.83SerLys: 5.83 ± 0.098
6.711SerLeu: 6.711 ± 0.132
1.416SerMet: 1.416 ± 0.053
3.478SerAsn: 3.478 ± 0.107
1.763SerPro: 1.763 ± 0.054
2.387SerGln: 2.387 ± 0.063
2.238SerArg: 2.238 ± 0.062
4.864SerSer: 4.864 ± 0.12
2.926SerThr: 2.926 ± 0.087
4.958SerVal: 4.958 ± 0.105
0.472SerTrp: 0.472 ± 0.032
2.576SerTyr: 2.576 ± 0.077
0.0SerXaa: 0.0 ± 0.0
Thr
3.6ThrAla: 3.6 ± 0.105
0.378ThrCys: 0.378 ± 0.026
2.601ThrAsp: 2.601 ± 0.087
1.927ThrGlu: 1.927 ± 0.064
2.052ThrPhe: 2.052 ± 0.072
2.847ThrGly: 2.847 ± 0.081
1.009ThrHis: 1.009 ± 0.043
4.097ThrIle: 4.097 ± 0.105
4.074ThrLys: 4.074 ± 0.08
5.044ThrLeu: 5.044 ± 0.091
0.954ThrMet: 0.954 ± 0.043
2.904ThrAsn: 2.904 ± 0.094
2.32ThrPro: 2.32 ± 0.072
2.122ThrGln: 2.122 ± 0.066
1.539ThrArg: 1.539 ± 0.057
3.195ThrSer: 3.195 ± 0.08
2.781ThrThr: 2.781 ± 0.093
1.095ThrVal: 1.095 ± 0.066
0.271ThrTrp: 0.271 ± 0.025
1.58ThrTyr: 1.58 ± 0.059
0.0ThrXaa: 0.0 ± 0.0
Val
5.379ValAla: 5.379 ± 0.11
0.949ValCys: 0.949 ± 0.049
3.416ValAsp: 3.416 ± 0.09
3.345ValGlu: 3.345 ± 0.08
3.243ValPhe: 3.243 ± 0.096
4.334ValGly: 4.334 ± 0.092
0.665ValHis: 0.665 ± 0.039
4.94ValIle: 4.94 ± 0.102
5.285ValLys: 5.285 ± 0.105
6.103ValLeu: 6.103 ± 0.127
1.498ValMet: 1.498 ± 0.054
2.79ValAsn: 2.79 ± 0.064
1.819ValPro: 1.819 ± 0.057
1.273ValGln: 1.273 ± 0.046
2.181ValArg: 2.181 ± 0.065
4.573ValSer: 4.573 ± 0.096
2.46ValThr: 2.46 ± 0.092
4.957ValVal: 4.957 ± 0.119
0.46ValTrp: 0.46 ± 0.031
1.89ValTyr: 1.89 ± 0.062
0.0ValXaa: 0.0 ± 0.0
Trp
0.56TrpAla: 0.56 ± 0.03
0.07TrpCys: 0.07 ± 0.011
0.398TrpAsp: 0.398 ± 0.031
0.314TrpGlu: 0.314 ± 0.023
0.332TrpPhe: 0.332 ± 0.025
0.547TrpGly: 0.547 ± 0.031
0.16TrpHis: 0.16 ± 0.016
0.519TrpIle: 0.519 ± 0.03
0.25TrpLys: 0.25 ± 0.02
0.792TrpLeu: 0.792 ± 0.04
0.196TrpMet: 0.196 ± 0.019
0.207TrpAsn: 0.207 ± 0.02
0.08TrpPro: 0.08 ± 0.011
0.333TrpGln: 0.333 ± 0.028
0.303TrpArg: 0.303 ± 0.024
0.396TrpSer: 0.396 ± 0.032
0.203TrpThr: 0.203 ± 0.021
0.435TrpVal: 0.435 ± 0.032
0.105TrpTrp: 0.105 ± 0.013
0.259TrpTyr: 0.259 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.616TyrAla: 2.616 ± 0.078
0.332TyrCys: 0.332 ± 0.023
2.387TyrAsp: 2.387 ± 0.062
2.922TyrGlu: 2.922 ± 0.079
2.097TyrPhe: 2.097 ± 0.069
2.255TyrGly: 2.255 ± 0.067
0.578TyrHis: 0.578 ± 0.033
2.396TyrIle: 2.396 ± 0.065
3.224TyrLys: 3.224 ± 0.073
3.092TyrLeu: 3.092 ± 0.072
0.656TyrMet: 0.656 ± 0.032
1.69TyrAsn: 1.69 ± 0.063
1.171TyrPro: 1.171 ± 0.045
0.961TyrGln: 0.961 ± 0.044
1.132TyrArg: 1.132 ± 0.047
2.027TyrSer: 2.027 ± 0.074
1.756TyrThr: 1.756 ± 0.056
1.808TyrVal: 1.808 ± 0.057
0.226TyrTrp: 0.226 ± 0.02
1.278TyrTyr: 1.278 ± 0.049
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1843 proteins (560879 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski