Amino acid dipepetide frequency for Pirital mammarenavirus (isolate Rat/Venezuela/VAV-488/1995) (PIRV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.778AlaAla: 1.778 ± 0.518
1.778AlaCys: 1.778 ± 1.254
2.075AlaAsp: 2.075 ± 0.294
1.778AlaGlu: 1.778 ± 0.888
1.482AlaPhe: 1.482 ± 0.469
2.964AlaGly: 2.964 ± 2.055
0.593AlaHis: 0.593 ± 0.296
2.667AlaIle: 2.667 ± 0.465
2.371AlaLys: 2.371 ± 0.448
7.41AlaLeu: 7.41 ± 1.386
0.296AlaMet: 0.296 ± 0.148
0.889AlaAsn: 0.889 ± 1.137
1.778AlaPro: 1.778 ± 1.094
1.778AlaGln: 1.778 ± 1.007
1.186AlaArg: 1.186 ± 1.072
2.964AlaSer: 2.964 ± 1.073
1.186AlaThr: 1.186 ± 0.303
2.371AlaVal: 2.371 ± 0.799
0.593AlaTrp: 0.593 ± 0.565
0.889AlaTyr: 0.889 ± 0.311
0.0AlaXaa: 0.0 ± 0.0
Cys
0.593CysAla: 0.593 ± 0.299
0.0CysCys: 0.0 ± 0.0
1.186CysAsp: 1.186 ± 1.072
1.778CysGlu: 1.778 ± 0.59
1.482CysPhe: 1.482 ± 0.611
1.482CysGly: 1.482 ± 2.415
0.296CysHis: 0.296 ± 0.148
1.186CysIle: 1.186 ± 0.303
2.371CysLys: 2.371 ± 1.264
3.26CysLeu: 3.26 ± 2.164
1.186CysMet: 1.186 ± 0.598
2.075CysAsn: 2.075 ± 0.479
1.482CysPro: 1.482 ± 0.469
0.296CysGln: 0.296 ± 0.148
0.889CysArg: 0.889 ± 0.311
2.371CysSer: 2.371 ± 1.725
1.186CysThr: 1.186 ± 0.37
2.075CysVal: 2.075 ± 0.72
0.593CysTrp: 0.593 ± 1.247
1.778CysTyr: 1.778 ± 0.214
0.0CysXaa: 0.0 ± 0.0
Asp
2.075AspAla: 2.075 ± 0.651
0.889AspCys: 0.889 ± 0.262
2.667AspAsp: 2.667 ± 0.693
4.149AspGlu: 4.149 ± 1.265
4.149AspPhe: 4.149 ± 1.265
2.964AspGly: 2.964 ± 0.418
1.186AspHis: 1.186 ± 1.109
2.075AspIle: 2.075 ± 1.392
4.446AspLys: 4.446 ± 1.172
8.002AspLeu: 8.002 ± 1.566
2.371AspMet: 2.371 ± 0.396
4.149AspAsn: 4.149 ± 0.729
1.778AspPro: 1.778 ± 0.519
2.075AspGln: 2.075 ± 0.548
2.075AspArg: 2.075 ± 0.294
2.964AspSer: 2.964 ± 0.44
2.371AspThr: 2.371 ± 1.041
4.446AspVal: 4.446 ± 1.147
1.186AspTrp: 1.186 ± 0.592
1.482AspTyr: 1.482 ± 0.74
0.0AspXaa: 0.0 ± 0.0
Glu
1.778GluAla: 1.778 ± 0.549
1.186GluCys: 1.186 ± 0.592
3.853GluAsp: 3.853 ± 1.507
6.224GluGlu: 6.224 ± 1.546
3.26GluPhe: 3.26 ± 1.055
3.26GluGly: 3.26 ± 1.265
1.482GluHis: 1.482 ± 0.74
3.853GluIle: 3.853 ± 1.924
3.26GluLys: 3.26 ± 0.914
6.224GluLeu: 6.224 ± 0.921
0.889GluMet: 0.889 ± 0.262
2.667GluAsn: 2.667 ± 0.782
1.482GluPro: 1.482 ± 1.125
4.149GluGln: 4.149 ± 1.659
2.964GluArg: 2.964 ± 0.925
6.224GluSer: 6.224 ± 1.517
2.075GluThr: 2.075 ± 0.294
5.631GluVal: 5.631 ± 1.287
0.296GluTrp: 0.296 ± 0.385
2.667GluTyr: 2.667 ± 0.832
0.0GluXaa: 0.0 ± 0.0
Phe
2.075PheAla: 2.075 ± 1.082
1.186PheCys: 1.186 ± 1.249
4.149PheAsp: 4.149 ± 0.882
2.667PheGlu: 2.667 ± 1.118
2.371PhePhe: 2.371 ± 0.916
2.667PheGly: 2.667 ± 0.364
0.889PheHis: 0.889 ± 0.444
3.26PheIle: 3.26 ± 0.83
4.446PheLys: 4.446 ± 1.411
4.446PheLeu: 4.446 ± 1.576
1.482PheMet: 1.482 ± 0.74
2.371PheAsn: 2.371 ± 1.252
0.593PhePro: 0.593 ± 0.296
1.482PheGln: 1.482 ± 0.22
2.371PheArg: 2.371 ± 0.414
3.26PheSer: 3.26 ± 1.217
1.778PheThr: 1.778 ± 0.952
3.557PheVal: 3.557 ± 1.039
1.482PheTrp: 1.482 ± 0.611
1.482PheTyr: 1.482 ± 0.469
0.0PheXaa: 0.0 ± 0.0
Gly
2.371GlyAla: 2.371 ± 0.448
1.186GlyCys: 1.186 ± 0.37
2.371GlyAsp: 2.371 ± 0.956
3.557GlyGlu: 3.557 ± 1.056
3.557GlyPhe: 3.557 ± 0.674
3.853GlyGly: 3.853 ± 1.668
0.593GlyHis: 0.593 ± 0.317
3.853GlyIle: 3.853 ± 1.268
3.26GlyLys: 3.26 ± 1.365
6.817GlyLeu: 6.817 ± 3.444
0.889GlyMet: 0.889 ± 0.262
2.964GlyAsn: 2.964 ± 1.266
1.186GlyPro: 1.186 ± 0.37
2.075GlyGln: 2.075 ± 0.734
2.075GlyArg: 2.075 ± 2.389
5.631GlySer: 5.631 ± 2.173
1.186GlyThr: 1.186 ± 0.308
2.964GlyVal: 2.964 ± 0.418
0.296GlyTrp: 0.296 ± 0.392
2.075GlyTyr: 2.075 ± 0.423
0.0GlyXaa: 0.0 ± 0.0
His
0.593HisAla: 0.593 ± 0.785
1.482HisCys: 1.482 ± 0.633
1.186HisAsp: 1.186 ± 0.303
1.186HisGlu: 1.186 ± 0.592
1.186HisPhe: 1.186 ± 0.635
1.482HisGly: 1.482 ± 1.125
0.593HisHis: 0.593 ± 0.317
1.482HisIle: 1.482 ± 0.469
1.186HisLys: 1.186 ± 0.303
2.667HisLeu: 2.667 ± 0.832
0.593HisMet: 0.593 ± 0.296
1.482HisAsn: 1.482 ± 0.469
0.593HisPro: 0.593 ± 0.299
0.0HisGln: 0.0 ± 0.0
1.482HisArg: 1.482 ± 0.611
0.889HisSer: 0.889 ± 0.311
0.889HisThr: 0.889 ± 0.311
2.371HisVal: 2.371 ± 1.27
0.0HisTrp: 0.0 ± 0.0
0.889HisTyr: 0.889 ± 1.389
0.0HisXaa: 0.0 ± 0.0
Ile
1.778IleAla: 1.778 ± 1.04
0.889IleCys: 0.889 ± 1.137
3.557IleAsp: 3.557 ± 0.625
2.964IleGlu: 2.964 ± 0.804
2.371IlePhe: 2.371 ± 0.789
3.557IleGly: 3.557 ± 1.099
1.186IleHis: 1.186 ± 0.303
2.371IleIle: 2.371 ± 1.051
6.224IleLys: 6.224 ± 1.146
6.52IleLeu: 6.52 ± 2.091
2.667IleMet: 2.667 ± 0.93
2.371IleAsn: 2.371 ± 1.051
2.075IlePro: 2.075 ± 1.318
2.075IleGln: 2.075 ± 1.398
2.667IleArg: 2.667 ± 1.03
4.742IleSer: 4.742 ± 0.828
3.853IleThr: 3.853 ± 0.633
4.446IleVal: 4.446 ± 0.703
0.593IleTrp: 0.593 ± 0.296
1.186IleTyr: 1.186 ± 0.592
0.0IleXaa: 0.0 ± 0.0
Lys
3.557LysAla: 3.557 ± 0.597
2.667LysCys: 2.667 ± 1.634
4.446LysAsp: 4.446 ± 1.956
5.335LysGlu: 5.335 ± 0.978
4.149LysPhe: 4.149 ± 0.974
4.149LysGly: 4.149 ± 1.128
0.889LysHis: 0.889 ± 0.43
6.224LysIle: 6.224 ± 1.266
4.149LysLys: 4.149 ± 1.299
8.002LysLeu: 8.002 ± 1.396
0.889LysMet: 0.889 ± 0.311
3.557LysAsn: 3.557 ± 0.625
3.26LysPro: 3.26 ± 0.957
1.482LysGln: 1.482 ± 0.469
3.853LysArg: 3.853 ± 1.169
6.52LysSer: 6.52 ± 1.313
3.557LysThr: 3.557 ± 1.109
3.557LysVal: 3.557 ± 0.91
1.186LysTrp: 1.186 ± 0.37
2.667LysTyr: 2.667 ± 0.693
0.0LysXaa: 0.0 ± 0.0
Leu
4.149LeuAla: 4.149 ± 2.711
4.742LeuCys: 4.742 ± 1.004
7.706LeuAsp: 7.706 ± 2.108
8.002LeuGlu: 8.002 ± 1.403
2.371LeuPhe: 2.371 ± 0.857
3.26LeuGly: 3.26 ± 0.407
2.371LeuHis: 2.371 ± 0.739
8.595LeuIle: 8.595 ± 0.916
8.002LeuLys: 8.002 ± 1.644
10.373LeuLeu: 10.373 ± 1.893
4.446LeuMet: 4.446 ± 0.859
10.077LeuAsn: 10.077 ± 1.985
3.557LeuPro: 3.557 ± 2.144
2.371LeuGln: 2.371 ± 0.414
7.41LeuArg: 7.41 ± 2.364
11.559LeuSer: 11.559 ± 2.652
8.595LeuThr: 8.595 ± 1.268
6.224LeuVal: 6.224 ± 1.935
0.889LeuTrp: 0.889 ± 0.69
3.26LeuTyr: 3.26 ± 1.14
0.0LeuXaa: 0.0 ± 0.0
Met
1.778MetAla: 1.778 ± 0.861
0.296MetCys: 0.296 ± 0.148
1.482MetAsp: 1.482 ± 0.74
0.889MetGlu: 0.889 ± 0.262
2.371MetPhe: 2.371 ± 1.041
1.482MetGly: 1.482 ± 1.154
0.296MetHis: 0.296 ± 0.392
2.075MetIle: 2.075 ± 0.294
1.482MetLys: 1.482 ± 0.469
3.853MetLeu: 3.853 ± 0.633
0.296MetMet: 0.296 ± 0.148
0.889MetAsn: 0.889 ± 0.43
0.889MetPro: 0.889 ± 0.262
0.889MetGln: 0.889 ± 0.311
1.482MetArg: 1.482 ± 0.633
4.149MetSer: 4.149 ± 1.265
2.371MetThr: 2.371 ± 1.09
0.889MetVal: 0.889 ± 0.444
0.0MetTrp: 0.0 ± 0.0
0.593MetTyr: 0.593 ± 0.296
0.0MetXaa: 0.0 ± 0.0
Asn
1.186AsnAla: 1.186 ± 0.37
2.371AsnCys: 2.371 ± 2.36
2.964AsnAsp: 2.964 ± 0.44
2.964AsnGlu: 2.964 ± 1.222
1.778AsnPhe: 1.778 ± 0.888
1.186AsnGly: 1.186 ± 0.76
2.075AsnHis: 2.075 ± 0.294
2.667AsnIle: 2.667 ± 0.996
4.149AsnLys: 4.149 ± 0.589
6.224AsnLeu: 6.224 ± 1.25
2.667AsnMet: 2.667 ± 0.699
1.482AsnAsn: 1.482 ± 0.611
2.964AsnPro: 2.964 ± 1.086
2.075AsnGln: 2.075 ± 0.294
2.371AsnArg: 2.371 ± 1.052
4.446AsnSer: 4.446 ± 1.4
2.964AsnThr: 2.964 ± 1.77
2.667AsnVal: 2.667 ± 1.291
0.593AsnTrp: 0.593 ± 0.299
1.482AsnTyr: 1.482 ± 0.22
0.0AsnXaa: 0.0 ± 0.0
Pro
1.482ProAla: 1.482 ± 0.543
0.889ProCys: 0.889 ± 0.262
2.667ProAsp: 2.667 ± 1.332
1.482ProGlu: 1.482 ± 0.646
1.778ProPhe: 1.778 ± 0.59
1.778ProGly: 1.778 ± 1.512
1.778ProHis: 1.778 ± 0.518
1.186ProIle: 1.186 ± 0.592
2.964ProLys: 2.964 ± 0.939
3.557ProLeu: 3.557 ± 0.985
1.186ProMet: 1.186 ± 2.085
2.371ProAsn: 2.371 ± 0.788
0.889ProPro: 0.889 ± 1.518
1.482ProGln: 1.482 ± 1.21
0.593ProArg: 0.593 ± 0.299
2.964ProSer: 2.964 ± 1.164
2.075ProThr: 2.075 ± 1.214
1.186ProVal: 1.186 ± 1.072
0.0ProTrp: 0.0 ± 0.0
1.778ProTyr: 1.778 ± 1.32
0.0ProXaa: 0.0 ± 0.0
Gln
1.778GlnAla: 1.778 ± 0.898
0.889GlnCys: 0.889 ± 0.311
0.889GlnAsp: 0.889 ± 0.444
2.075GlnGlu: 2.075 ± 0.651
2.964GlnPhe: 2.964 ± 0.963
3.26GlnGly: 3.26 ± 1.14
0.296GlnHis: 0.296 ± 0.385
1.778GlnIle: 1.778 ± 0.518
2.371GlnLys: 2.371 ± 0.616
5.039GlnLeu: 5.039 ± 0.881
0.0GlnMet: 0.0 ± 0.0
0.889GlnAsn: 0.889 ± 0.69
0.889GlnPro: 0.889 ± 1.177
1.186GlnGln: 1.186 ± 0.592
1.482GlnArg: 1.482 ± 0.977
4.149GlnSer: 4.149 ± 0.746
0.593GlnThr: 0.593 ± 0.296
2.964GlnVal: 2.964 ± 0.804
0.296GlnTrp: 0.296 ± 0.385
0.593GlnTyr: 0.593 ± 0.565
0.0GlnXaa: 0.0 ± 0.0
Arg
1.778ArgAla: 1.778 ± 0.525
0.889ArgCys: 0.889 ± 0.444
2.667ArgAsp: 2.667 ± 0.787
3.557ArgGlu: 3.557 ± 1.138
1.778ArgPhe: 1.778 ± 2.275
3.26ArgGly: 3.26 ± 1.11
2.075ArgHis: 2.075 ± 1.68
2.371ArgIle: 2.371 ± 1.184
3.853ArgLys: 3.853 ± 0.493
7.113ArgLeu: 7.113 ± 0.867
1.482ArgMet: 1.482 ± 0.646
1.482ArgAsn: 1.482 ± 0.633
0.296ArgPro: 0.296 ± 0.148
1.482ArgGln: 1.482 ± 0.22
2.075ArgArg: 2.075 ± 0.423
4.149ArgSer: 4.149 ± 0.883
2.667ArgThr: 2.667 ± 0.364
2.371ArgVal: 2.371 ± 1.395
1.186ArgTrp: 1.186 ± 0.308
1.186ArgTyr: 1.186 ± 1.125
0.0ArgXaa: 0.0 ± 0.0
Ser
2.667SerAla: 2.667 ± 1.112
2.371SerCys: 2.371 ± 1.252
5.631SerAsp: 5.631 ± 1.557
5.039SerGlu: 5.039 ± 1.719
3.853SerPhe: 3.853 ± 0.993
4.446SerGly: 4.446 ± 1.202
2.964SerHis: 2.964 ± 0.418
5.335SerIle: 5.335 ± 1.246
7.706SerLys: 7.706 ± 1.765
11.559SerLeu: 11.559 ± 2.371
3.853SerMet: 3.853 ± 1.169
4.149SerAsn: 4.149 ± 0.974
3.853SerPro: 3.853 ± 0.992
4.149SerGln: 4.149 ± 2.137
2.964SerArg: 2.964 ± 0.688
8.299SerSer: 8.299 ± 2.204
3.26SerThr: 3.26 ± 0.83
4.149SerVal: 4.149 ± 1.299
0.593SerTrp: 0.593 ± 0.296
2.964SerTyr: 2.964 ± 0.939
0.0SerXaa: 0.0 ± 0.0
Thr
1.482ThrAla: 1.482 ± 0.646
0.296ThrCys: 0.296 ± 0.148
2.371ThrAsp: 2.371 ± 1.197
2.371ThrGlu: 2.371 ± 0.789
1.778ThrPhe: 1.778 ± 0.888
1.778ThrGly: 1.778 ± 0.549
1.186ThrHis: 1.186 ± 1.542
2.964ThrIle: 2.964 ± 0.418
4.149ThrLys: 4.149 ± 0.888
5.039ThrLeu: 5.039 ± 1.318
0.889ThrMet: 0.889 ± 0.893
2.667ThrAsn: 2.667 ± 0.937
2.075ThrPro: 2.075 ± 0.294
2.075ThrGln: 2.075 ± 1.753
3.853ThrArg: 3.853 ± 0.795
5.335ThrSer: 5.335 ± 1.374
4.742ThrThr: 4.742 ± 2.449
2.371ThrVal: 2.371 ± 1.051
1.482ThrTrp: 1.482 ± 1.126
0.296ThrTyr: 0.296 ± 0.148
0.0ThrXaa: 0.0 ± 0.0
Val
4.446ValAla: 4.446 ± 1.021
2.075ValCys: 2.075 ± 1.036
3.557ValAsp: 3.557 ± 0.91
4.446ValGlu: 4.446 ± 0.653
3.26ValPhe: 3.26 ± 1.055
2.964ValGly: 2.964 ± 0.524
0.889ValHis: 0.889 ± 0.444
1.186ValIle: 1.186 ± 1.242
4.742ValLys: 4.742 ± 2.394
7.706ValLeu: 7.706 ± 1.291
1.482ValMet: 1.482 ± 0.611
2.964ValAsn: 2.964 ± 1.138
2.371ValPro: 2.371 ± 1.052
2.667ValGln: 2.667 ± 0.693
3.853ValArg: 3.853 ± 0.795
5.631ValSer: 5.631 ± 1.001
1.778ValThr: 1.778 ± 1.019
4.446ValVal: 4.446 ± 1.44
0.889ValTrp: 0.889 ± 0.893
1.186ValTyr: 1.186 ± 0.303
0.0ValXaa: 0.0 ± 0.0
Trp
0.593TrpAla: 0.593 ± 0.771
0.0TrpCys: 0.0 ± 0.0
1.482TrpAsp: 1.482 ± 1.13
0.593TrpGlu: 0.593 ± 0.317
0.593TrpPhe: 0.593 ± 1.168
0.593TrpGly: 0.593 ± 0.317
0.593TrpHis: 0.593 ± 0.296
0.296TrpIle: 0.296 ± 0.392
0.296TrpLys: 0.296 ± 0.385
2.075TrpLeu: 2.075 ± 0.923
0.296TrpMet: 0.296 ± 0.148
0.0TrpAsn: 0.0 ± 0.0
0.889TrpPro: 0.889 ± 0.43
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.889TrpSer: 0.889 ± 0.311
0.593TrpThr: 0.593 ± 0.785
2.075TrpVal: 2.075 ± 0.667
0.0TrpTrp: 0.0 ± 0.0
0.593TrpTyr: 0.593 ± 0.317
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.889TyrAla: 0.889 ± 0.262
1.482TyrCys: 1.482 ± 0.611
0.593TyrAsp: 0.593 ± 0.296
2.371TyrGlu: 2.371 ± 0.956
1.482TyrPhe: 1.482 ± 0.74
2.371TyrGly: 2.371 ± 1.264
0.0TyrHis: 0.0 ± 0.0
2.667TyrIle: 2.667 ± 0.787
2.667TyrLys: 2.667 ± 1.22
2.371TyrLeu: 2.371 ± 1.052
0.296TyrMet: 0.296 ± 0.148
1.778TyrAsn: 1.778 ± 1.019
1.186TyrPro: 1.186 ± 0.598
0.593TyrGln: 0.593 ± 0.296
2.075TyrArg: 2.075 ± 0.548
2.667TyrSer: 2.667 ± 0.978
1.482TyrThr: 1.482 ± 0.22
1.778TyrVal: 1.778 ± 0.59
0.296TyrTrp: 0.296 ± 0.148
0.593TyrTyr: 0.593 ± 0.317
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3375 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski