human papillomavirus 71

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 14

Average proteome isoelectric point is 6.43

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q6EGQ2|Q6EGQ2_9PAPI Protein E6 OS=human papillomavirus 71 OX=120686 GN=E6 PE=3 SV=1
MM1 pKa = 8.13RR2 pKa = 11.84GQQCTLKK9 pKa = 10.9DD10 pKa = 3.2IVLQLQPEE18 pKa = 4.54VVDD21 pKa = 5.6LYY23 pKa = 10.9CHH25 pKa = 5.68EE26 pKa = 4.49QFASSDD32 pKa = 3.51EE33 pKa = 3.99GDD35 pKa = 3.33NRR37 pKa = 11.84VDD39 pKa = 3.72GEE41 pKa = 4.46QPTEE45 pKa = 3.98PAQQAYY51 pKa = 9.33RR52 pKa = 11.84VVSYY56 pKa = 10.61CGRR59 pKa = 11.84CCRR62 pKa = 11.84AVRR65 pKa = 11.84LVVEE69 pKa = 4.5SDD71 pKa = 3.23EE72 pKa = 4.38ADD74 pKa = 3.07IRR76 pKa = 11.84ALQQLLLGTLTIVCPICVV94 pKa = 3.27

Molecular weight: 10.5 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q6EGQ1|Q6EGQ1_9PAPI Protein E7 OS=human papillomavirus 71 OX=120686 GN=E7 PE=3 SV=1
MM1 pKa = 6.76MHH3 pKa = 6.39STPLCLAPRR12 pKa = 11.84TPSKK16 pKa = 9.87TKK18 pKa = 10.69YY19 pKa = 9.79PLLNLLTTGPTRR31 pKa = 11.84TPNRR35 pKa = 11.84PPPPPKK41 pKa = 9.83CWAPTKK47 pKa = 9.32PKK49 pKa = 10.13CRR51 pKa = 11.84PRR53 pKa = 11.84HH54 pKa = 5.57LSDD57 pKa = 3.99SDD59 pKa = 4.13SEE61 pKa = 4.42TDD63 pKa = 3.38SGPLSSPILQKK74 pKa = 10.51HH75 pKa = 5.39HH76 pKa = 6.66SSWHH80 pKa = 5.01VSTLGPSVTLTAHH93 pKa = 6.68TSTGGHH99 pKa = 4.29VTVTVHH105 pKa = 6.96LL106 pKa = 4.36

Molecular weight: 11.47 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2358

94

642

336.9

37.5

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.167 ± 0.32

2.799 ± 0.677

5.98 ± 0.493

5.131 ± 0.562

3.69 ± 0.498

6.573 ± 0.486

2.46 ± 0.461

4.241 ± 0.533

4.453 ± 0.562

8.482 ± 0.698

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.696 ± 0.221

3.138 ± 0.331

6.404 ± 1.234

4.877 ± 0.645

5.81 ± 0.187

7.209 ± 0.84

8.142 ± 0.851

6.701 ± 0.456

1.654 ± 0.373

3.393 ± 0.209
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski