Amino acid dipepetide frequency for Trametes pubescens (White-rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.324AlaAla: 11.324 ± 0.075	1.135AlaCys: 1.135 ± 0.015	5.158AlaAsp: 5.158 ± 0.033	5.673AlaGlu: 5.673 ± 0.035	3.487AlaPhe: 3.487 ± 0.029	6.373AlaGly: 6.373 ± 0.037	2.635AlaHis: 2.635 ± 0.022	4.002AlaIle: 4.002 ± 0.027	3.921AlaLys: 3.921 ± 0.034	9.567AlaLeu: 9.567 ± 0.056	2.063AlaMet: 2.063 ± 0.017	2.787AlaAsn: 2.787 ± 0.024	6.959AlaPro: 6.959 ± 0.051	3.922AlaGln: 3.922 ± 0.032	6.676AlaArg: 6.676 ± 0.035	8.414AlaSer: 8.414 ± 0.048	5.804AlaThr: 5.804 ± 0.038	6.253AlaVal: 6.253 ± 0.041	1.297AlaTrp: 1.297 ± 0.016	2.399AlaTyr: 2.399 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.158CysAla: 1.158 ± 0.015	0.236CysCys: 0.236 ± 0.007	0.661CysAsp: 0.661 ± 0.011	0.62CysGlu: 0.62 ± 0.011	0.424CysPhe: 0.424 ± 0.008	0.915CysGly: 0.915 ± 0.013	0.296CysHis: 0.296 ± 0.008	0.607CysIle: 0.607 ± 0.01	0.464CysLys: 0.464 ± 0.009	1.097CysLeu: 1.097 ± 0.015	0.26CysMet: 0.26 ± 0.007	0.356CysAsn: 0.356 ± 0.008	0.77CysPro: 0.77 ± 0.013	0.384CysGln: 0.384 ± 0.008	0.778CysArg: 0.778 ± 0.013	0.836CysSer: 0.836 ± 0.012	0.732CysThr: 0.732 ± 0.012	0.813CysVal: 0.813 ± 0.012	0.189CysTrp: 0.189 ± 0.006	0.31CysTyr: 0.31 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	6.154AspAla: 6.154 ± 0.037	0.61AspCys: 0.61 ± 0.011	4.499AspAsp: 4.499 ± 0.039	4.54AspGlu: 4.54 ± 0.036	2.043AspPhe: 2.043 ± 0.021	4.233AspGly: 4.233 ± 0.031	1.215AspHis: 1.215 ± 0.016	2.84AspIle: 2.84 ± 0.02	2.011AspLys: 2.011 ± 0.019	4.912AspLeu: 4.912 ± 0.032	1.257AspMet: 1.257 ± 0.013	1.512AspAsn: 1.512 ± 0.014	3.69AspPro: 3.69 ± 0.027	1.521AspGln: 1.521 ± 0.016	2.991AspArg: 2.991 ± 0.027	3.885AspSer: 3.885 ± 0.027	3.093AspThr: 3.093 ± 0.026	4.432AspVal: 4.432 ± 0.034	0.902AspTrp: 0.902 ± 0.012	1.451AspTyr: 1.451 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.512GluAla: 5.512 ± 0.037	0.662GluCys: 0.662 ± 0.01	4.597GluAsp: 4.597 ± 0.033	5.407GluGlu: 5.407 ± 0.056	1.813GluPhe: 1.813 ± 0.018	3.797GluGly: 3.797 ± 0.029	1.62GluHis: 1.62 ± 0.018	2.452GluIle: 2.452 ± 0.022	2.888GluLys: 2.888 ± 0.028	5.526GluLeu: 5.526 ± 0.033	1.304GluMet: 1.304 ± 0.015	1.671GluAsn: 1.671 ± 0.017	3.0GluPro: 3.0 ± 0.028	2.276GluGln: 2.276 ± 0.022	4.437GluArg: 4.437 ± 0.034	3.72GluSer: 3.72 ± 0.029	2.962GluThr: 2.962 ± 0.026	3.783GluVal: 3.783 ± 0.028	0.978GluTrp: 0.978 ± 0.014	1.549GluTyr: 1.549 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.417PheAla: 3.417 ± 0.026	0.487PheCys: 0.487 ± 0.009	2.204PheAsp: 2.204 ± 0.019	1.939PheGlu: 1.939 ± 0.018	1.383PhePhe: 1.383 ± 0.014	2.594PheGly: 2.594 ± 0.027	0.86PheHis: 0.86 ± 0.013	1.475PheIle: 1.475 ± 0.018	1.332PheLys: 1.332 ± 0.016	3.252PheLeu: 3.252 ± 0.025	0.714PheMet: 0.714 ± 0.011	1.148PheAsn: 1.148 ± 0.015	2.085PhePro: 2.085 ± 0.021	1.125PheGln: 1.125 ± 0.014	1.966PheArg: 1.966 ± 0.019	2.754PheSer: 2.754 ± 0.024	2.036PheThr: 2.036 ± 0.022	2.485PheVal: 2.485 ± 0.021	0.561PheTrp: 0.561 ± 0.01	0.926PheTyr: 0.926 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	6.18GlyAla: 6.18 ± 0.044	0.822GlyCys: 0.822 ± 0.014	3.62GlyAsp: 3.62 ± 0.028	3.708GlyGlu: 3.708 ± 0.028	2.406GlyPhe: 2.406 ± 0.024	5.69GlyGly: 5.69 ± 0.056	1.706GlyHis: 1.706 ± 0.019	2.844GlyIle: 2.844 ± 0.026	3.135GlyLys: 3.135 ± 0.024	5.584GlyLeu: 5.584 ± 0.031	1.485GlyMet: 1.485 ± 0.018	1.952GlyAsn: 1.952 ± 0.022	3.808GlyPro: 3.808 ± 0.03	2.31GlyGln: 2.31 ± 0.02	4.363GlyArg: 4.363 ± 0.028	5.523GlySer: 5.523 ± 0.039	4.042GlyThr: 4.042 ± 0.027	4.393GlyVal: 4.393 ± 0.03	1.128GlyTrp: 1.128 ± 0.013	1.779GlyTyr: 1.779 ± 0.02	0.001GlyXaa: 0.001 ± 0.0
His	2.576HisAla: 2.576 ± 0.024	0.344HisCys: 0.344 ± 0.008	1.408HisAsp: 1.408 ± 0.018	1.317HisGlu: 1.317 ± 0.016	0.927HisPhe: 0.927 ± 0.015	1.747HisGly: 1.747 ± 0.017	0.827HisHis: 0.827 ± 0.016	1.279HisIle: 1.279 ± 0.016	0.879HisLys: 0.879 ± 0.013	2.511HisLeu: 2.511 ± 0.024	0.511HisMet: 0.511 ± 0.009	0.744HisAsn: 0.744 ± 0.011	2.075HisPro: 2.075 ± 0.019	0.83HisGln: 0.83 ± 0.012	1.678HisArg: 1.678 ± 0.015	1.985HisSer: 1.985 ± 0.021	1.545HisThr: 1.545 ± 0.016	1.746HisVal: 1.746 ± 0.018	0.391HisTrp: 0.391 ± 0.009	0.679HisTyr: 0.679 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.061IleAla: 4.061 ± 0.026	0.598IleCys: 0.598 ± 0.009	2.531IleAsp: 2.531 ± 0.02	2.398IleGlu: 2.398 ± 0.024	1.556IlePhe: 1.556 ± 0.018	2.647IleGly: 2.647 ± 0.022	1.077IleHis: 1.077 ± 0.014	1.915IleIle: 1.915 ± 0.021	1.629IleLys: 1.629 ± 0.018	3.883IleLeu: 3.883 ± 0.03	0.836IleMet: 0.836 ± 0.015	1.287IleAsn: 1.287 ± 0.014	3.043IlePro: 3.043 ± 0.023	1.481IleGln: 1.481 ± 0.014	2.622IleArg: 2.622 ± 0.021	3.102IleSer: 3.102 ± 0.024	2.413IleThr: 2.413 ± 0.021	3.029IleVal: 3.029 ± 0.026	0.634IleTrp: 0.634 ± 0.01	1.074IleTyr: 1.074 ± 0.014	0.001IleXaa: 0.001 ± 0.0
Lys	4.192LysAla: 4.192 ± 0.035	0.428LysCys: 0.428 ± 0.009	2.306LysAsp: 2.306 ± 0.022	2.745LysGlu: 2.745 ± 0.028	1.185LysPhe: 1.185 ± 0.016	2.649LysGly: 2.649 ± 0.024	1.097LysHis: 1.097 ± 0.012	1.675LysIle: 1.675 ± 0.019	2.67LysLys: 2.67 ± 0.035	3.608LysLeu: 3.608 ± 0.027	0.842LysMet: 0.842 ± 0.012	1.204LysAsn: 1.204 ± 0.017	2.5LysPro: 2.5 ± 0.024	1.488LysGln: 1.488 ± 0.015	3.235LysArg: 3.235 ± 0.03	2.651LysSer: 2.651 ± 0.027	2.399LysThr: 2.399 ± 0.02	2.466LysVal: 2.466 ± 0.024	0.603LysTrp: 0.603 ± 0.01	1.115LysTyr: 1.115 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	9.012LeuAla: 9.012 ± 0.047	1.242LeuCys: 1.242 ± 0.017	5.311LeuAsp: 5.311 ± 0.033	5.463LeuGlu: 5.463 ± 0.038	3.128LeuPhe: 3.128 ± 0.027	5.61LeuGly: 5.61 ± 0.033	2.489LeuHis: 2.489 ± 0.024	3.267LeuIle: 3.267 ± 0.025	3.682LeuLys: 3.682 ± 0.03	8.396LeuLeu: 8.396 ± 0.056	1.659LeuMet: 1.659 ± 0.017	2.726LeuAsn: 2.726 ± 0.024	6.596LeuPro: 6.596 ± 0.031	3.706LeuGln: 3.706 ± 0.026	6.657LeuArg: 6.657 ± 0.043	7.405LeuSer: 7.405 ± 0.042	5.059LeuThr: 5.059 ± 0.033	5.787LeuVal: 5.787 ± 0.04	1.234LeuTrp: 1.234 ± 0.015	2.278LeuTyr: 2.278 ± 0.022	0.001LeuXaa: 0.001 ± 0.0
Met	1.942MetAla: 1.942 ± 0.017	0.241MetCys: 0.241 ± 0.006	1.244MetAsp: 1.244 ± 0.015	1.13MetGlu: 1.13 ± 0.013	0.736MetPhe: 0.736 ± 0.011	1.251MetGly: 1.251 ± 0.018	0.589MetHis: 0.589 ± 0.01	0.748MetIle: 0.748 ± 0.012	0.804MetLys: 0.804 ± 0.011	1.864MetLeu: 1.864 ± 0.017	0.461MetMet: 0.461 ± 0.01	0.667MetAsn: 0.667 ± 0.011	1.412MetPro: 1.412 ± 0.017	0.83MetGln: 0.83 ± 0.012	1.419MetArg: 1.419 ± 0.016	1.953MetSer: 1.953 ± 0.019	1.124MetThr: 1.124 ± 0.014	1.165MetVal: 1.165 ± 0.014	0.276MetTrp: 0.276 ± 0.007	0.508MetTyr: 0.508 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.165AsnAla: 3.165 ± 0.026	0.332AsnCys: 0.332 ± 0.007	1.527AsnAsp: 1.527 ± 0.016	1.505AsnGlu: 1.505 ± 0.017	1.067AsnPhe: 1.067 ± 0.013	2.402AsnGly: 2.402 ± 0.025	0.677AsnHis: 0.677 ± 0.011	1.543AsnIle: 1.543 ± 0.017	1.081AsnLys: 1.081 ± 0.015	2.674AsnLeu: 2.674 ± 0.021	0.684AsnMet: 0.684 ± 0.012	0.983AsnAsn: 0.983 ± 0.016	2.075AsnPro: 2.075 ± 0.019	0.891AsnGln: 0.891 ± 0.013	1.491AsnArg: 1.491 ± 0.016	2.03AsnSer: 2.03 ± 0.019	1.899AsnThr: 1.899 ± 0.018	2.173AsnVal: 2.173 ± 0.02	0.437AsnTrp: 0.437 ± 0.008	0.763AsnTyr: 0.763 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	7.326ProAla: 7.326 ± 0.052	0.549ProCys: 0.549 ± 0.009	3.57ProAsp: 3.57 ± 0.024	4.025ProGlu: 4.025 ± 0.03	2.195ProPhe: 2.195 ± 0.02	4.308ProGly: 4.308 ± 0.03	1.739ProHis: 1.739 ± 0.022	2.538ProIle: 2.538 ± 0.021	2.425ProLys: 2.425 ± 0.024	5.685ProLeu: 5.685 ± 0.035	1.163ProMet: 1.163 ± 0.014	1.977ProAsn: 1.977 ± 0.02	7.565ProPro: 7.565 ± 0.082	2.615ProGln: 2.615 ± 0.034	4.287ProArg: 4.287 ± 0.032	7.381ProSer: 7.381 ± 0.058	4.657ProThr: 4.657 ± 0.035	4.214ProVal: 4.214 ± 0.028	0.762ProTrp: 0.762 ± 0.011	1.622ProTyr: 1.622 ± 0.018	0.001ProXaa: 0.001 ± 0.0
Gln	3.606GlnAla: 3.606 ± 0.029	0.428GlnCys: 0.428 ± 0.009	1.941GlnAsp: 1.941 ± 0.02	2.212GlnGlu: 2.212 ± 0.021	1.181GlnPhe: 1.181 ± 0.013	2.203GlnGly: 2.203 ± 0.021	1.077GlnHis: 1.077 ± 0.016	1.434GlnIle: 1.434 ± 0.018	1.434GlnLys: 1.434 ± 0.019	3.279GlnLeu: 3.279 ± 0.026	0.771GlnMet: 0.771 ± 0.012	1.131GlnAsn: 1.131 ± 0.014	2.543GlnPro: 2.543 ± 0.034	2.001GlnGln: 2.001 ± 0.042	2.62GlnArg: 2.62 ± 0.026	2.731GlnSer: 2.731 ± 0.025	2.128GlnThr: 2.128 ± 0.022	2.103GlnVal: 2.103 ± 0.018	0.566GlnTrp: 0.566 ± 0.009	1.063GlnTyr: 1.063 ± 0.014	0.001GlnXaa: 0.001 ± 0.0
Arg	6.663ArgAla: 6.663 ± 0.04	0.829ArgCys: 0.829 ± 0.013	3.545ArgAsp: 3.545 ± 0.027	4.202ArgGlu: 4.202 ± 0.033	2.185ArgPhe: 2.185 ± 0.019	3.999ArgGly: 3.999 ± 0.036	1.722ArgHis: 1.722 ± 0.017	2.825ArgIle: 2.825 ± 0.025	3.266ArgLys: 3.266 ± 0.032	5.97ArgLeu: 5.97 ± 0.044	1.469ArgMet: 1.469 ± 0.015	1.888ArgAsn: 1.888 ± 0.022	4.178ArgPro: 4.178 ± 0.033	2.319ArgGln: 2.319 ± 0.022	5.772ArgArg: 5.772 ± 0.039	5.057ArgSer: 5.057 ± 0.035	3.981ArgThr: 3.981 ± 0.026	4.131ArgVal: 4.131 ± 0.028	1.046ArgTrp: 1.046 ± 0.013	1.687ArgTyr: 1.687 ± 0.02	0.001ArgXaa: 0.001 ± 0.0
Ser	8.096SerAla: 8.096 ± 0.052	0.832SerCys: 0.832 ± 0.014	4.274SerAsp: 4.274 ± 0.031	3.949SerGlu: 3.949 ± 0.027	2.718SerPhe: 2.718 ± 0.023	5.518SerGly: 5.518 ± 0.037	1.956SerHis: 1.956 ± 0.018	3.233SerIle: 3.233 ± 0.026	2.958SerLys: 2.958 ± 0.025	7.057SerLeu: 7.057 ± 0.042	1.636SerMet: 1.636 ± 0.018	2.246SerAsn: 2.246 ± 0.022	6.529SerPro: 6.529 ± 0.063	2.851SerGln: 2.851 ± 0.029	5.138SerArg: 5.138 ± 0.033	9.041SerSer: 9.041 ± 0.076	5.656SerThr: 5.656 ± 0.037	4.935SerVal: 4.935 ± 0.03	1.041SerTrp: 1.041 ± 0.014	1.776SerTyr: 1.776 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.682ThrAla: 5.682 ± 0.039	0.71ThrCys: 0.71 ± 0.012	2.857ThrAsp: 2.857 ± 0.023	2.826ThrGlu: 2.826 ± 0.022	2.304ThrPhe: 2.304 ± 0.022	3.844ThrGly: 3.844 ± 0.027	1.531ThrHis: 1.531 ± 0.017	2.662ThrIle: 2.662 ± 0.022	2.121ThrLys: 2.121 ± 0.023	5.853ThrLeu: 5.853 ± 0.038	1.109ThrMet: 1.109 ± 0.013	1.731ThrAsn: 1.731 ± 0.018	4.986ThrPro: 4.986 ± 0.038	1.98ThrGln: 1.98 ± 0.02	3.584ThrArg: 3.584 ± 0.027	5.349ThrSer: 5.349 ± 0.042	4.06ThrThr: 4.06 ± 0.037	3.974ThrVal: 3.974 ± 0.028	0.815ThrTrp: 0.815 ± 0.013	1.523ThrTyr: 1.523 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	6.134ValAla: 6.134 ± 0.035	0.862ValCys: 0.862 ± 0.013	4.023ValAsp: 4.023 ± 0.026	3.988ValGlu: 3.988 ± 0.032	2.48ValPhe: 2.48 ± 0.021	3.969ValGly: 3.969 ± 0.03	1.797ValHis: 1.797 ± 0.019	2.693ValIle: 2.693 ± 0.024	2.672ValLys: 2.672 ± 0.023	6.227ValLeu: 6.227 ± 0.038	1.248ValMet: 1.248 ± 0.015	1.973ValAsn: 1.973 ± 0.019	4.543ValPro: 4.543 ± 0.029	2.497ValGln: 2.497 ± 0.017	4.316ValArg: 4.316 ± 0.033	4.847ValSer: 4.847 ± 0.032	3.465ValThr: 3.465 ± 0.03	4.722ValVal: 4.722 ± 0.036	0.993ValTrp: 0.993 ± 0.013	1.769ValTyr: 1.769 ± 0.019	0.001ValXaa: 0.001 ± 0.0
Trp	1.234TrpAla: 1.234 ± 0.014	0.211TrpCys: 0.211 ± 0.006	0.898TrpAsp: 0.898 ± 0.013	0.876TrpGlu: 0.876 ± 0.013	0.54TrpPhe: 0.54 ± 0.01	0.886TrpGly: 0.886 ± 0.011	0.387TrpHis: 0.387 ± 0.009	0.633TrpIle: 0.633 ± 0.011	0.728TrpLys: 0.728 ± 0.01	1.331TrpLeu: 1.331 ± 0.016	0.352TrpMet: 0.352 ± 0.008	0.551TrpAsn: 0.551 ± 0.01	0.713TrpPro: 0.713 ± 0.011	0.532TrpGln: 0.532 ± 0.01	1.113TrpArg: 1.113 ± 0.015	1.022TrpSer: 1.022 ± 0.012	0.917TrpThr: 0.917 ± 0.013	0.883TrpVal: 0.883 ± 0.013	0.281TrpTrp: 0.281 ± 0.007	0.422TrpTyr: 0.422 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.415TyrAla: 2.415 ± 0.021	0.346TyrCys: 0.346 ± 0.008	1.616TyrAsp: 1.616 ± 0.015	1.432TyrGlu: 1.432 ± 0.017	0.988TyrPhe: 0.988 ± 0.014	1.843TyrGly: 1.843 ± 0.022	0.703TyrHis: 0.703 ± 0.012	1.153TyrIle: 1.153 ± 0.014	0.958TyrLys: 0.958 ± 0.013	2.431TyrLeu: 2.431 ± 0.024	0.542TyrMet: 0.542 ± 0.01	0.866TyrAsn: 0.866 ± 0.013	1.532TyrPro: 1.532 ± 0.02	0.891TyrGln: 0.891 ± 0.012	1.589TyrArg: 1.589 ± 0.017	1.756TyrSer: 1.756 ± 0.017	1.523TyrThr: 1.523 ± 0.016	1.73TyrVal: 1.73 ± 0.018	0.377TyrTrp: 0.377 ± 0.008	0.77TyrTyr: 0.77 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 14147 proteins (6007546 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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