Amino acid dipepetide frequency for Bivalve RNA virus G4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.042AlaAla: 7.042 ± 0.0
0.829AlaCys: 0.829 ± 0.0
2.486AlaAsp: 2.486 ± 0.0
4.143AlaGlu: 4.143 ± 0.0
3.314AlaPhe: 3.314 ± 0.0
7.871AlaGly: 7.871 ± 0.0
2.9AlaHis: 2.9 ± 0.0
4.143AlaIle: 4.143 ± 0.0
3.728AlaLys: 3.728 ± 0.0
6.214AlaLeu: 6.214 ± 0.0
2.486AlaMet: 2.486 ± 0.0
2.9AlaAsn: 2.9 ± 0.0
5.8AlaPro: 5.8 ± 0.0
2.486AlaGln: 2.486 ± 0.0
3.728AlaArg: 3.728 ± 0.0
7.042AlaSer: 7.042 ± 0.0
9.114AlaThr: 9.114 ± 0.0
8.699AlaVal: 8.699 ± 0.0
1.657AlaTrp: 1.657 ± 0.0
1.657AlaTyr: 1.657 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.657CysAla: 1.657 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.243CysAsp: 1.243 ± 0.0
1.243CysGlu: 1.243 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.829CysGly: 0.829 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.414CysIle: 0.414 ± 0.0
0.414CysLys: 0.414 ± 0.0
0.414CysLeu: 0.414 ± 0.0
0.414CysMet: 0.414 ± 0.0
0.829CysAsn: 0.829 ± 0.0
0.829CysPro: 0.829 ± 0.0
0.414CysGln: 0.414 ± 0.0
0.414CysArg: 0.414 ± 0.0
1.243CysSer: 1.243 ± 0.0
0.829CysThr: 0.829 ± 0.0
1.657CysVal: 1.657 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.414CysTyr: 0.414 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
9.114AspAla: 9.114 ± 0.0
0.414AspCys: 0.414 ± 0.0
4.971AspAsp: 4.971 ± 0.0
3.314AspGlu: 3.314 ± 0.0
3.728AspPhe: 3.728 ± 0.0
2.071AspGly: 2.071 ± 0.0
1.657AspHis: 1.657 ± 0.0
3.728AspIle: 3.728 ± 0.0
3.314AspLys: 3.314 ± 0.0
6.628AspLeu: 6.628 ± 0.0
3.314AspMet: 3.314 ± 0.0
2.071AspAsn: 2.071 ± 0.0
2.9AspPro: 2.9 ± 0.0
2.486AspGln: 2.486 ± 0.0
1.657AspArg: 1.657 ± 0.0
4.557AspSer: 4.557 ± 0.0
2.9AspThr: 2.9 ± 0.0
4.971AspVal: 4.971 ± 0.0
0.0AspTrp: 0.0 ± 0.0
1.243AspTyr: 1.243 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.385GluAla: 5.385 ± 0.0
0.414GluCys: 0.414 ± 0.0
1.657GluAsp: 1.657 ± 0.0
1.243GluGlu: 1.243 ± 0.0
1.657GluPhe: 1.657 ± 0.0
2.486GluGly: 2.486 ± 0.0
1.657GluHis: 1.657 ± 0.0
2.9GluIle: 2.9 ± 0.0
2.486GluLys: 2.486 ± 0.0
4.557GluLeu: 4.557 ± 0.0
0.0GluMet: 0.0 ± 0.0
2.9GluAsn: 2.9 ± 0.0
2.486GluPro: 2.486 ± 0.0
3.314GluGln: 3.314 ± 0.0
3.728GluArg: 3.728 ± 0.0
2.486GluSer: 2.486 ± 0.0
3.314GluThr: 3.314 ± 0.0
3.728GluVal: 3.728 ± 0.0
0.414GluTrp: 0.414 ± 0.0
0.414GluTyr: 0.414 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.728PheAla: 3.728 ± 0.0
0.0PheCys: 0.0 ± 0.0
4.143PheAsp: 4.143 ± 0.0
1.657PheGlu: 1.657 ± 0.0
1.243PhePhe: 1.243 ± 0.0
3.728PheGly: 3.728 ± 0.0
0.414PheHis: 0.414 ± 0.0
0.829PheIle: 0.829 ± 0.0
2.486PheLys: 2.486 ± 0.0
2.486PheLeu: 2.486 ± 0.0
0.829PheMet: 0.829 ± 0.0
2.486PheAsn: 2.486 ± 0.0
0.829PhePro: 0.829 ± 0.0
1.243PheGln: 1.243 ± 0.0
2.486PheArg: 2.486 ± 0.0
2.9PheSer: 2.9 ± 0.0
4.557PheThr: 4.557 ± 0.0
4.557PheVal: 4.557 ± 0.0
0.414PheTrp: 0.414 ± 0.0
2.071PheTyr: 2.071 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.628GlyAla: 6.628 ± 0.0
1.657GlyCys: 1.657 ± 0.0
4.971GlyAsp: 4.971 ± 0.0
3.314GlyGlu: 3.314 ± 0.0
3.728GlyPhe: 3.728 ± 0.0
3.728GlyGly: 3.728 ± 0.0
0.829GlyHis: 0.829 ± 0.0
4.143GlyIle: 4.143 ± 0.0
2.486GlyLys: 2.486 ± 0.0
6.628GlyLeu: 6.628 ± 0.0
0.414GlyMet: 0.414 ± 0.0
2.9GlyAsn: 2.9 ± 0.0
4.143GlyPro: 4.143 ± 0.0
1.657GlyGln: 1.657 ± 0.0
4.143GlyArg: 4.143 ± 0.0
3.728GlySer: 3.728 ± 0.0
2.9GlyThr: 2.9 ± 0.0
4.143GlyVal: 4.143 ± 0.0
1.243GlyTrp: 1.243 ± 0.0
2.071GlyTyr: 2.071 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.071HisAla: 2.071 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.071HisAsp: 2.071 ± 0.0
3.728HisGlu: 3.728 ± 0.0
2.486HisPhe: 2.486 ± 0.0
0.829HisGly: 0.829 ± 0.0
0.414HisHis: 0.414 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.414HisLys: 0.414 ± 0.0
1.243HisLeu: 1.243 ± 0.0
0.414HisMet: 0.414 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.243HisPro: 1.243 ± 0.0
0.829HisGln: 0.829 ± 0.0
1.243HisArg: 1.243 ± 0.0
0.829HisSer: 0.829 ± 0.0
2.486HisThr: 2.486 ± 0.0
2.486HisVal: 2.486 ± 0.0
0.414HisTrp: 0.414 ± 0.0
2.486HisTyr: 2.486 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.314IleAla: 3.314 ± 0.0
0.414IleCys: 0.414 ± 0.0
3.728IleAsp: 3.728 ± 0.0
2.486IleGlu: 2.486 ± 0.0
2.486IlePhe: 2.486 ± 0.0
2.9IleGly: 2.9 ± 0.0
0.829IleHis: 0.829 ± 0.0
1.243IleIle: 1.243 ± 0.0
1.657IleLys: 1.657 ± 0.0
1.657IleLeu: 1.657 ± 0.0
1.657IleMet: 1.657 ± 0.0
1.243IleAsn: 1.243 ± 0.0
3.314IlePro: 3.314 ± 0.0
0.829IleGln: 0.829 ± 0.0
2.071IleArg: 2.071 ± 0.0
3.728IleSer: 3.728 ± 0.0
2.486IleThr: 2.486 ± 0.0
3.728IleVal: 3.728 ± 0.0
0.0IleTrp: 0.0 ± 0.0
0.414IleTyr: 0.414 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.071LysAla: 2.071 ± 0.0
0.829LysCys: 0.829 ± 0.0
3.314LysAsp: 3.314 ± 0.0
2.071LysGlu: 2.071 ± 0.0
1.243LysPhe: 1.243 ± 0.0
2.486LysGly: 2.486 ± 0.0
2.071LysHis: 2.071 ± 0.0
2.486LysIle: 2.486 ± 0.0
2.486LysLys: 2.486 ± 0.0
3.314LysLeu: 3.314 ± 0.0
0.414LysMet: 0.414 ± 0.0
2.071LysAsn: 2.071 ± 0.0
2.9LysPro: 2.9 ± 0.0
2.071LysGln: 2.071 ± 0.0
1.243LysArg: 1.243 ± 0.0
1.657LysSer: 1.657 ± 0.0
3.728LysThr: 3.728 ± 0.0
1.243LysVal: 1.243 ± 0.0
0.829LysTrp: 0.829 ± 0.0
3.314LysTyr: 3.314 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.214LeuAla: 6.214 ± 0.0
1.243LeuCys: 1.243 ± 0.0
2.486LeuAsp: 2.486 ± 0.0
4.143LeuGlu: 4.143 ± 0.0
3.314LeuPhe: 3.314 ± 0.0
6.628LeuGly: 6.628 ± 0.0
2.9LeuHis: 2.9 ± 0.0
3.314LeuIle: 3.314 ± 0.0
4.971LeuLys: 4.971 ± 0.0
8.285LeuLeu: 8.285 ± 0.0
1.657LeuMet: 1.657 ± 0.0
3.728LeuAsn: 3.728 ± 0.0
4.143LeuPro: 4.143 ± 0.0
1.243LeuGln: 1.243 ± 0.0
4.971LeuArg: 4.971 ± 0.0
10.771LeuSer: 10.771 ± 0.0
4.971LeuThr: 4.971 ± 0.0
6.628LeuVal: 6.628 ± 0.0
0.829LeuTrp: 0.829 ± 0.0
2.071LeuTyr: 2.071 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.9MetAla: 2.9 ± 0.0
0.414MetCys: 0.414 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.486MetGlu: 2.486 ± 0.0
0.414MetPhe: 0.414 ± 0.0
1.243MetGly: 1.243 ± 0.0
1.657MetHis: 1.657 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.829MetLys: 0.829 ± 0.0
4.143MetLeu: 4.143 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.829MetAsn: 0.829 ± 0.0
1.243MetPro: 1.243 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.414MetArg: 0.414 ± 0.0
1.657MetSer: 1.657 ± 0.0
1.243MetThr: 1.243 ± 0.0
1.657MetVal: 1.657 ± 0.0
0.414MetTrp: 0.414 ± 0.0
1.243MetTyr: 1.243 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.9AsnAla: 2.9 ± 0.0
0.0AsnCys: 0.0 ± 0.0
3.314AsnAsp: 3.314 ± 0.0
2.486AsnGlu: 2.486 ± 0.0
2.486AsnPhe: 2.486 ± 0.0
4.971AsnGly: 4.971 ± 0.0
0.414AsnHis: 0.414 ± 0.0
1.657AsnIle: 1.657 ± 0.0
1.243AsnLys: 1.243 ± 0.0
3.728AsnLeu: 3.728 ± 0.0
1.243AsnMet: 1.243 ± 0.0
1.243AsnAsn: 1.243 ± 0.0
3.728AsnPro: 3.728 ± 0.0
2.9AsnGln: 2.9 ± 0.0
2.071AsnArg: 2.071 ± 0.0
2.071AsnSer: 2.071 ± 0.0
2.9AsnThr: 2.9 ± 0.0
3.314AsnVal: 3.314 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
0.829AsnTyr: 0.829 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.314ProAla: 3.314 ± 0.0
1.243ProCys: 1.243 ± 0.0
2.486ProAsp: 2.486 ± 0.0
2.071ProGlu: 2.071 ± 0.0
1.657ProPhe: 1.657 ± 0.0
4.557ProGly: 4.557 ± 0.0
2.486ProHis: 2.486 ± 0.0
2.9ProIle: 2.9 ± 0.0
1.657ProLys: 1.657 ± 0.0
4.143ProLeu: 4.143 ± 0.0
1.243ProMet: 1.243 ± 0.0
3.314ProAsn: 3.314 ± 0.0
2.9ProPro: 2.9 ± 0.0
0.414ProGln: 0.414 ± 0.0
3.314ProArg: 3.314 ± 0.0
4.143ProSer: 4.143 ± 0.0
5.385ProThr: 5.385 ± 0.0
4.971ProVal: 4.971 ± 0.0
0.414ProTrp: 0.414 ± 0.0
2.9ProTyr: 2.9 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.9GlnAla: 2.9 ± 0.0
0.414GlnCys: 0.414 ± 0.0
1.657GlnAsp: 1.657 ± 0.0
1.243GlnGlu: 1.243 ± 0.0
3.314GlnPhe: 3.314 ± 0.0
0.414GlnGly: 0.414 ± 0.0
1.657GlnHis: 1.657 ± 0.0
1.243GlnIle: 1.243 ± 0.0
0.414GlnLys: 0.414 ± 0.0
3.728GlnLeu: 3.728 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.243GlnAsn: 1.243 ± 0.0
2.486GlnPro: 2.486 ± 0.0
1.243GlnGln: 1.243 ± 0.0
2.486GlnArg: 2.486 ± 0.0
0.829GlnSer: 0.829 ± 0.0
2.486GlnThr: 2.486 ± 0.0
2.486GlnVal: 2.486 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.657GlnTyr: 1.657 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.214ArgAla: 6.214 ± 0.0
0.829ArgCys: 0.829 ± 0.0
5.385ArgAsp: 5.385 ± 0.0
1.657ArgGlu: 1.657 ± 0.0
2.486ArgPhe: 2.486 ± 0.0
2.486ArgGly: 2.486 ± 0.0
1.243ArgHis: 1.243 ± 0.0
1.657ArgIle: 1.657 ± 0.0
4.557ArgLys: 4.557 ± 0.0
5.385ArgLeu: 5.385 ± 0.0
1.657ArgMet: 1.657 ± 0.0
3.728ArgAsn: 3.728 ± 0.0
1.243ArgPro: 1.243 ± 0.0
2.071ArgGln: 2.071 ± 0.0
3.728ArgArg: 3.728 ± 0.0
1.243ArgSer: 1.243 ± 0.0
4.143ArgThr: 4.143 ± 0.0
4.557ArgVal: 4.557 ± 0.0
0.414ArgTrp: 0.414 ± 0.0
0.414ArgTyr: 0.414 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.214SerAla: 6.214 ± 0.0
1.657SerCys: 1.657 ± 0.0
5.385SerAsp: 5.385 ± 0.0
2.486SerGlu: 2.486 ± 0.0
3.314SerPhe: 3.314 ± 0.0
4.557SerGly: 4.557 ± 0.0
1.657SerHis: 1.657 ± 0.0
2.9SerIle: 2.9 ± 0.0
2.071SerLys: 2.071 ± 0.0
8.699SerLeu: 8.699 ± 0.0
1.657SerMet: 1.657 ± 0.0
3.728SerAsn: 3.728 ± 0.0
2.9SerPro: 2.9 ± 0.0
1.243SerGln: 1.243 ± 0.0
4.557SerArg: 4.557 ± 0.0
7.042SerSer: 7.042 ± 0.0
2.9SerThr: 2.9 ± 0.0
5.8SerVal: 5.8 ± 0.0
0.829SerTrp: 0.829 ± 0.0
2.9SerTyr: 2.9 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.628ThrAla: 6.628 ± 0.0
1.243ThrCys: 1.243 ± 0.0
4.971ThrAsp: 4.971 ± 0.0
2.486ThrGlu: 2.486 ± 0.0
2.9ThrPhe: 2.9 ± 0.0
3.728ThrGly: 3.728 ± 0.0
1.243ThrHis: 1.243 ± 0.0
2.9ThrIle: 2.9 ± 0.0
3.314ThrLys: 3.314 ± 0.0
3.728ThrLeu: 3.728 ± 0.0
2.071ThrMet: 2.071 ± 0.0
2.486ThrAsn: 2.486 ± 0.0
4.971ThrPro: 4.971 ± 0.0
2.071ThrGln: 2.071 ± 0.0
4.143ThrArg: 4.143 ± 0.0
6.214ThrSer: 6.214 ± 0.0
11.599ThrThr: 11.599 ± 0.0
4.971ThrVal: 4.971 ± 0.0
1.243ThrTrp: 1.243 ± 0.0
4.143ThrTyr: 4.143 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.971ValAla: 4.971 ± 0.0
1.657ValCys: 1.657 ± 0.0
6.214ValAsp: 6.214 ± 0.0
3.728ValGlu: 3.728 ± 0.0
3.314ValPhe: 3.314 ± 0.0
7.457ValGly: 7.457 ± 0.0
1.243ValHis: 1.243 ± 0.0
2.9ValIle: 2.9 ± 0.0
1.243ValLys: 1.243 ± 0.0
4.557ValLeu: 4.557 ± 0.0
2.486ValMet: 2.486 ± 0.0
4.971ValAsn: 4.971 ± 0.0
4.971ValPro: 4.971 ± 0.0
2.486ValGln: 2.486 ± 0.0
3.728ValArg: 3.728 ± 0.0
8.285ValSer: 8.285 ± 0.0
4.971ValThr: 4.971 ± 0.0
6.628ValVal: 6.628 ± 0.0
1.243ValTrp: 1.243 ± 0.0
3.314ValTyr: 3.314 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.829TrpAla: 0.829 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.243TrpAsp: 1.243 ± 0.0
0.414TrpGlu: 0.414 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.414TrpHis: 0.414 ± 0.0
0.414TrpIle: 0.414 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.243TrpLeu: 1.243 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.414TrpPro: 0.414 ± 0.0
0.414TrpGln: 0.414 ± 0.0
2.486TrpArg: 2.486 ± 0.0
0.414TrpSer: 0.414 ± 0.0
0.414TrpThr: 0.414 ± 0.0
1.243TrpVal: 1.243 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.829TrpTyr: 0.829 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.143TyrAla: 4.143 ± 0.0
0.0TyrCys: 0.0 ± 0.0
3.314TyrAsp: 3.314 ± 0.0
0.829TyrGlu: 0.829 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
2.486TyrGly: 2.486 ± 0.0
0.0TyrHis: 0.0 ± 0.0
0.414TyrIle: 0.414 ± 0.0
2.486TyrLys: 2.486 ± 0.0
3.728TyrLeu: 3.728 ± 0.0
0.414TyrMet: 0.414 ± 0.0
0.829TyrAsn: 0.829 ± 0.0
2.071TyrPro: 2.071 ± 0.0
2.486TyrGln: 2.486 ± 0.0
2.486TyrArg: 2.486 ± 0.0
1.657TyrSer: 1.657 ± 0.0
3.728TyrThr: 3.728 ± 0.0
2.9TyrVal: 2.9 ± 0.0
0.414TyrTrp: 0.414 ± 0.0
1.657TyrTyr: 1.657 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2415 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski