Amino acid dipepetide frequency for Hubei sobemo-like virus 37

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.086AlaAla: 1.086 ± 0.924
1.086AlaCys: 1.086 ± 0.924
0.0AlaAsp: 0.0 ± 0.0
2.172AlaGlu: 2.172 ± 1.848
2.172AlaPhe: 2.172 ± 1.098
2.172AlaGly: 2.172 ± 0.796
0.0AlaHis: 0.0 ± 0.0
1.086AlaIle: 1.086 ± 0.851
2.172AlaLys: 2.172 ± 1.702
1.086AlaLeu: 1.086 ± 0.851
1.086AlaMet: 1.086 ± 0.924
0.0AlaAsn: 0.0 ± 0.0
3.257AlaPro: 3.257 ± 1.456
1.086AlaGln: 1.086 ± 0.924
4.343AlaArg: 4.343 ± 3.696
3.257AlaSer: 3.257 ± 1.456
1.086AlaThr: 1.086 ± 0.924
1.086AlaVal: 1.086 ± 0.851
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.086CysGlu: 1.086 ± 0.924
0.0CysPhe: 0.0 ± 0.0
1.086CysGly: 1.086 ± 0.924
0.0CysHis: 0.0 ± 0.0
1.086CysIle: 1.086 ± 0.851
0.0CysLys: 0.0 ± 0.0
2.172CysLeu: 2.172 ± 0.791
0.0CysMet: 0.0 ± 0.0
2.172CysAsn: 2.172 ± 0.796
0.0CysPro: 0.0 ± 0.0
2.172CysGln: 2.172 ± 0.796
2.172CysArg: 2.172 ± 1.848
2.172CysSer: 2.172 ± 1.848
0.0CysThr: 0.0 ± 0.0
3.257CysVal: 3.257 ± 1.842
2.172CysTrp: 2.172 ± 1.848
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.172AspAla: 2.172 ± 1.848
0.0AspCys: 0.0 ± 0.0
5.429AspAsp: 5.429 ± 3.196
5.429AspGlu: 5.429 ± 3.196
1.086AspPhe: 1.086 ± 0.924
1.086AspGly: 1.086 ± 0.924
1.086AspHis: 1.086 ± 0.924
1.086AspIle: 1.086 ± 0.924
4.343AspLys: 4.343 ± 2.305
7.6AspLeu: 7.6 ± 0.584
0.0AspMet: 0.0 ± 0.0
3.257AspAsn: 3.257 ± 1.456
4.343AspPro: 4.343 ± 2.305
1.086AspGln: 1.086 ± 0.924
0.0AspArg: 0.0 ± 0.0
2.172AspSer: 2.172 ± 0.796
1.086AspThr: 1.086 ± 0.924
6.515AspVal: 6.515 ± 0.355
3.257AspTrp: 3.257 ± 1.456
1.086AspTyr: 1.086 ± 0.924
0.0AspXaa: 0.0 ± 0.0
Glu
1.086GluAla: 1.086 ± 0.924
2.172GluCys: 2.172 ± 1.848
4.343GluAsp: 4.343 ± 1.07
2.172GluGlu: 2.172 ± 1.848
1.086GluPhe: 1.086 ± 0.924
4.343GluGly: 4.343 ± 1.591
2.172GluHis: 2.172 ± 0.796
3.257GluIle: 3.257 ± 1.456
2.172GluLys: 2.172 ± 0.796
5.429GluLeu: 5.429 ± 1.676
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
1.086GluPro: 1.086 ± 0.924
1.086GluGln: 1.086 ± 0.851
0.0GluArg: 0.0 ± 0.0
2.172GluSer: 2.172 ± 1.848
1.086GluThr: 1.086 ± 0.851
3.257GluVal: 3.257 ± 0.178
0.0GluTrp: 0.0 ± 0.0
5.429GluTyr: 5.429 ± 3.252
0.0GluXaa: 0.0 ± 0.0
Phe
1.086PheAla: 1.086 ± 0.924
1.086PheCys: 1.086 ± 0.924
3.257PheAsp: 3.257 ± 1.495
0.0PheGlu: 0.0 ± 0.0
2.172PhePhe: 2.172 ± 0.791
2.172PheGly: 2.172 ± 1.848
0.0PheHis: 0.0 ± 0.0
4.343PheIle: 4.343 ± 1.582
3.257PheLys: 3.257 ± 1.456
9.772PheLeu: 9.772 ± 4.242
2.172PheMet: 2.172 ± 0.815
3.257PheAsn: 3.257 ± 1.456
2.172PhePro: 2.172 ± 0.796
5.429PheGln: 5.429 ± 0.678
3.257PheArg: 3.257 ± 1.495
3.257PheSer: 3.257 ± 1.456
0.0PheThr: 0.0 ± 0.0
3.257PheVal: 3.257 ± 1.733
1.086PheTrp: 1.086 ± 0.924
2.172PheTyr: 2.172 ± 1.848
0.0PheXaa: 0.0 ± 0.0
Gly
3.257GlyAla: 3.257 ± 0.178
1.086GlyCys: 1.086 ± 0.924
6.515GlyAsp: 6.515 ± 4.102
2.172GlyGlu: 2.172 ± 1.848
5.429GlyPhe: 5.429 ± 2.206
2.172GlyGly: 2.172 ± 0.796
2.172GlyHis: 2.172 ± 1.848
5.429GlyIle: 5.429 ± 1.272
2.172GlyLys: 2.172 ± 1.848
4.343GlyLeu: 4.343 ± 1.582
1.086GlyMet: 1.086 ± 0.851
1.086GlyAsn: 1.086 ± 0.924
1.086GlyPro: 1.086 ± 0.924
0.0GlyGln: 0.0 ± 0.0
2.172GlyArg: 2.172 ± 0.796
2.172GlySer: 2.172 ± 1.098
1.086GlyThr: 1.086 ± 0.924
0.0GlyVal: 0.0 ± 0.0
1.086GlyTrp: 1.086 ± 0.924
2.172GlyTyr: 2.172 ± 1.098
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.086HisCys: 1.086 ± 0.924
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.086HisPhe: 1.086 ± 0.924
0.0HisGly: 0.0 ± 0.0
1.086HisHis: 1.086 ± 0.851
0.0HisIle: 0.0 ± 0.0
1.086HisLys: 1.086 ± 0.924
4.343HisLeu: 4.343 ± 0.752
1.086HisMet: 1.086 ± 0.851
1.086HisAsn: 1.086 ± 0.924
1.086HisPro: 1.086 ± 0.924
0.0HisGln: 0.0 ± 0.0
1.086HisArg: 1.086 ± 0.924
2.172HisSer: 2.172 ± 0.796
0.0HisThr: 0.0 ± 0.0
3.257HisVal: 3.257 ± 2.772
0.0HisTrp: 0.0 ± 0.0
5.429HisTyr: 5.429 ± 2.157
0.0HisXaa: 0.0 ± 0.0
Ile
1.086IleAla: 1.086 ± 0.924
1.086IleCys: 1.086 ± 0.851
1.086IleAsp: 1.086 ± 0.924
0.0IleGlu: 0.0 ± 0.0
2.172IlePhe: 2.172 ± 0.791
4.343IleGly: 4.343 ± 2.124
1.086IleHis: 1.086 ± 0.924
7.6IleIle: 7.6 ± 4.605
2.172IleLys: 2.172 ± 0.791
13.029IleLeu: 13.029 ± 5.259
2.172IleMet: 2.172 ± 0.791
1.086IleAsn: 1.086 ± 0.851
4.343IlePro: 4.343 ± 2.305
4.343IleGln: 4.343 ± 2.7
3.257IleArg: 3.257 ± 1.842
1.086IleSer: 1.086 ± 0.924
2.172IleThr: 2.172 ± 1.098
3.257IleVal: 3.257 ± 1.495
2.172IleTrp: 2.172 ± 0.791
3.257IleTyr: 3.257 ± 1.733
0.0IleXaa: 0.0 ± 0.0
Lys
2.172LysAla: 2.172 ± 1.702
2.172LysCys: 2.172 ± 1.848
4.343LysAsp: 4.343 ± 2.305
2.172LysGlu: 2.172 ± 0.796
5.429LysPhe: 5.429 ± 2.053
1.086LysGly: 1.086 ± 0.924
1.086LysHis: 1.086 ± 0.924
3.257LysIle: 3.257 ± 2.553
5.429LysLys: 5.429 ± 1.272
8.686LysLeu: 8.686 ± 0.598
3.257LysMet: 3.257 ± 1.842
2.172LysAsn: 2.172 ± 0.796
4.343LysPro: 4.343 ± 2.305
1.086LysGln: 1.086 ± 0.924
3.257LysArg: 3.257 ± 0.178
5.429LysSer: 5.429 ± 1.272
4.343LysThr: 4.343 ± 2.356
2.172LysVal: 2.172 ± 0.796
2.172LysTrp: 2.172 ± 0.791
2.172LysTyr: 2.172 ± 1.702
0.0LysXaa: 0.0 ± 0.0
Leu
5.429LeuAla: 5.429 ± 0.778
1.086LeuCys: 1.086 ± 0.924
6.515LeuAsp: 6.515 ± 4.16
7.6LeuGlu: 7.6 ± 2.179
6.515LeuPhe: 6.515 ± 2.63
8.686LeuGly: 8.686 ± 1.448
1.086LeuHis: 1.086 ± 0.851
4.343LeuIle: 4.343 ± 2.124
15.201LeuLys: 15.201 ± 4.497
24.973LeuLeu: 24.973 ± 9.161
4.343LeuMet: 4.343 ± 3.403
4.343LeuAsn: 4.343 ± 1.07
6.515LeuPro: 6.515 ± 2.63
1.086LeuGln: 1.086 ± 0.851
8.686LeuArg: 8.686 ± 0.8
10.858LeuSer: 10.858 ± 2.763
2.172LeuThr: 2.172 ± 1.848
20.63LeuVal: 20.63 ± 8.738
0.0LeuTrp: 0.0 ± 0.0
7.6LeuTyr: 7.6 ± 2.8
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
1.086MetCys: 1.086 ± 0.924
2.172MetAsp: 2.172 ± 1.848
1.086MetGlu: 1.086 ± 0.924
4.343MetPhe: 4.343 ± 0.752
0.0MetGly: 0.0 ± 0.0
1.086MetHis: 1.086 ± 0.924
2.172MetIle: 2.172 ± 1.702
4.343MetLys: 4.343 ± 2.124
5.429MetLeu: 5.429 ± 4.254
4.343MetMet: 4.343 ± 3.403
2.172MetAsn: 2.172 ± 1.702
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.086MetSer: 1.086 ± 0.924
0.0MetThr: 0.0 ± 0.0
7.6MetVal: 7.6 ± 3.846
0.0MetTrp: 0.0 ± 0.0
1.086MetTyr: 1.086 ± 0.851
0.0MetXaa: 0.0 ± 0.0
Asn
1.086AsnAla: 1.086 ± 0.924
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.086AsnGlu: 1.086 ± 0.924
3.257AsnPhe: 3.257 ± 2.772
2.172AsnGly: 2.172 ± 0.796
2.172AsnHis: 2.172 ± 0.796
1.086AsnIle: 1.086 ± 0.851
3.257AsnLys: 3.257 ± 1.456
6.515AsnLeu: 6.515 ± 4.134
1.086AsnMet: 1.086 ± 0.76
0.0AsnAsn: 0.0 ± 0.0
2.172AsnPro: 2.172 ± 1.098
1.086AsnGln: 1.086 ± 0.924
0.0AsnArg: 0.0 ± 0.0
4.343AsnSer: 4.343 ± 2.305
1.086AsnThr: 1.086 ± 0.924
3.257AsnVal: 3.257 ± 1.495
0.0AsnTrp: 0.0 ± 0.0
3.257AsnTyr: 3.257 ± 1.456
0.0AsnXaa: 0.0 ± 0.0
Pro
1.086ProAla: 1.086 ± 0.924
3.257ProCys: 3.257 ± 1.495
2.172ProAsp: 2.172 ± 0.791
3.257ProGlu: 3.257 ± 0.178
3.257ProPhe: 3.257 ± 1.456
1.086ProGly: 1.086 ± 0.924
1.086ProHis: 1.086 ± 0.924
1.086ProIle: 1.086 ± 0.851
1.086ProLys: 1.086 ± 0.924
5.429ProLeu: 5.429 ± 1.676
1.086ProMet: 1.086 ± 0.851
0.0ProAsn: 0.0 ± 0.0
2.172ProPro: 2.172 ± 1.702
2.172ProGln: 2.172 ± 1.098
2.172ProArg: 2.172 ± 1.848
2.172ProSer: 2.172 ± 1.848
2.172ProThr: 2.172 ± 0.796
4.343ProVal: 4.343 ± 1.07
0.0ProTrp: 0.0 ± 0.0
1.086ProTyr: 1.086 ± 0.924
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.086GlnAsp: 1.086 ± 0.924
1.086GlnGlu: 1.086 ± 0.924
2.172GlnPhe: 2.172 ± 0.791
2.172GlnGly: 2.172 ± 1.098
1.086GlnHis: 1.086 ± 0.851
2.172GlnIle: 2.172 ± 1.848
1.086GlnLys: 1.086 ± 0.924
6.515GlnLeu: 6.515 ± 1.882
3.257GlnMet: 3.257 ± 0.178
3.257GlnAsn: 3.257 ± 2.772
0.0GlnPro: 0.0 ± 0.0
2.172GlnGln: 2.172 ± 1.098
2.172GlnArg: 2.172 ± 1.848
1.086GlnSer: 1.086 ± 0.924
2.172GlnThr: 2.172 ± 0.796
0.0GlnVal: 0.0 ± 0.0
1.086GlnTrp: 1.086 ± 0.924
1.086GlnTyr: 1.086 ± 0.924
0.0GlnXaa: 0.0 ± 0.0
Arg
1.086ArgAla: 1.086 ± 0.924
1.086ArgCys: 1.086 ± 0.851
1.086ArgAsp: 1.086 ± 0.924
3.257ArgGlu: 3.257 ± 1.842
1.086ArgPhe: 1.086 ± 0.924
3.257ArgGly: 3.257 ± 1.733
2.172ArgHis: 2.172 ± 0.796
3.257ArgIle: 3.257 ± 1.842
1.086ArgLys: 1.086 ± 0.924
8.686ArgLeu: 8.686 ± 3.038
3.257ArgMet: 3.257 ± 0.178
2.172ArgAsn: 2.172 ± 1.848
0.0ArgPro: 0.0 ± 0.0
1.086ArgGln: 1.086 ± 0.924
3.257ArgArg: 3.257 ± 2.772
4.343ArgSer: 4.343 ± 1.591
3.257ArgThr: 3.257 ± 1.456
2.172ArgVal: 2.172 ± 1.848
3.257ArgTrp: 3.257 ± 1.495
2.172ArgTyr: 2.172 ± 1.848
0.0ArgXaa: 0.0 ± 0.0
Ser
3.257SerAla: 3.257 ± 0.178
1.086SerCys: 1.086 ± 0.924
2.172SerAsp: 2.172 ± 1.848
1.086SerGlu: 1.086 ± 0.924
5.429SerPhe: 5.429 ± 2.157
5.429SerGly: 5.429 ± 2.157
3.257SerHis: 3.257 ± 1.456
3.257SerIle: 3.257 ± 2.772
7.6SerLys: 7.6 ± 3.523
3.257SerLeu: 3.257 ± 1.358
3.257SerMet: 3.257 ± 1.495
3.257SerAsn: 3.257 ± 1.358
0.0SerPro: 0.0 ± 0.0
2.172SerGln: 2.172 ± 1.848
7.6SerArg: 7.6 ± 1.225
8.686SerSer: 8.686 ± 1.994
4.343SerThr: 4.343 ± 2.305
4.343SerVal: 4.343 ± 1.07
2.172SerTrp: 2.172 ± 1.702
3.257SerTyr: 3.257 ± 1.842
0.0SerXaa: 0.0 ± 0.0
Thr
2.172ThrAla: 2.172 ± 0.796
0.0ThrCys: 0.0 ± 0.0
2.172ThrAsp: 2.172 ± 1.848
0.0ThrGlu: 0.0 ± 0.0
1.086ThrPhe: 1.086 ± 0.924
1.086ThrGly: 1.086 ± 0.924
1.086ThrHis: 1.086 ± 0.924
1.086ThrIle: 1.086 ± 0.851
4.343ThrLys: 4.343 ± 1.591
3.257ThrLeu: 3.257 ± 1.456
0.0ThrMet: 0.0 ± 0.707
4.343ThrAsn: 4.343 ± 0.752
1.086ThrPro: 1.086 ± 0.924
2.172ThrGln: 2.172 ± 1.848
0.0ThrArg: 0.0 ± 0.0
3.257ThrSer: 3.257 ± 1.495
3.257ThrThr: 3.257 ± 2.772
2.172ThrVal: 2.172 ± 1.848
1.086ThrTrp: 1.086 ± 0.924
1.086ThrTyr: 1.086 ± 0.851
0.0ThrXaa: 0.0 ± 0.0
Val
2.172ValAla: 2.172 ± 1.098
1.086ValCys: 1.086 ± 0.924
5.429ValAsp: 5.429 ± 2.157
4.343ValGlu: 4.343 ± 1.582
3.257ValPhe: 3.257 ± 0.178
2.172ValGly: 2.172 ± 1.098
0.0ValHis: 0.0 ± 0.0
11.944ValIle: 11.944 ± 1.624
1.086ValLys: 1.086 ± 0.851
13.029ValLeu: 13.029 ± 7.5
4.343ValMet: 4.343 ± 3.403
1.086ValAsn: 1.086 ± 0.851
4.343ValPro: 4.343 ± 1.07
2.172ValGln: 2.172 ± 0.796
4.343ValArg: 4.343 ± 2.305
6.515ValSer: 6.515 ± 1.323
1.086ValThr: 1.086 ± 0.851
2.172ValVal: 2.172 ± 0.791
1.086ValTrp: 1.086 ± 0.851
4.343ValTyr: 4.343 ± 1.07
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.086TrpAsp: 1.086 ± 0.924
1.086TrpGlu: 1.086 ± 0.924
1.086TrpPhe: 1.086 ± 0.851
1.086TrpGly: 1.086 ± 0.924
1.086TrpHis: 1.086 ± 0.924
1.086TrpIle: 1.086 ± 0.924
1.086TrpLys: 1.086 ± 0.851
4.343TrpLeu: 4.343 ± 2.124
0.0TrpMet: 0.0 ± 0.0
1.086TrpAsn: 1.086 ± 0.924
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.086TrpArg: 1.086 ± 0.924
4.343TrpSer: 4.343 ± 2.356
1.086TrpThr: 1.086 ± 0.924
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
3.257TrpTyr: 3.257 ± 0.178
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.086TyrCys: 1.086 ± 0.924
3.257TyrAsp: 3.257 ± 2.772
3.257TyrGlu: 3.257 ± 2.772
1.086TyrPhe: 1.086 ± 0.924
1.086TyrGly: 1.086 ± 0.924
1.086TyrHis: 1.086 ± 0.924
2.172TyrIle: 2.172 ± 1.098
3.257TyrLys: 3.257 ± 1.358
9.772TyrLeu: 9.772 ± 0.533
1.086TyrMet: 1.086 ± 0.851
1.086TyrAsn: 1.086 ± 0.924
2.172TyrPro: 2.172 ± 1.702
3.257TyrGln: 3.257 ± 1.495
2.172TyrArg: 2.172 ± 1.098
4.343TyrSer: 4.343 ± 1.07
4.343TyrThr: 4.343 ± 1.591
3.257TyrVal: 3.257 ± 1.358
2.172TyrTrp: 2.172 ± 0.791
1.086TyrTyr: 1.086 ± 0.924
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (922 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski