Feline immunodeficiency virus (isolate Petaluma) (FIV)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Feline immunodeficiency virus

Average proteome isoelectric point is 7.67

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q66013|VPRL_FIVPE Probable Vpr-like protein OS=Feline immunodeficiency virus (isolate Petaluma) OX=11674 PE=3 SV=1
MM1 pKa = 7.81AEE3 pKa = 3.78GFAANRR9 pKa = 11.84QWIGLEE15 pKa = 3.93EE16 pKa = 4.69AEE18 pKa = 4.66EE19 pKa = 4.21LLDD22 pKa = 5.37FDD24 pKa = 5.07IATQMSEE31 pKa = 4.42EE32 pKa = 4.73GPLNPGVNPFRR43 pKa = 11.84VPGITEE49 pKa = 3.97KK50 pKa = 10.88EE51 pKa = 3.9KK52 pKa = 11.07QNYY55 pKa = 9.11CNILQPKK62 pKa = 9.25LQDD65 pKa = 3.53LRR67 pKa = 11.84NEE69 pKa = 3.81IQEE72 pKa = 4.36VKK74 pKa = 10.76LEE76 pKa = 4.07EE77 pKa = 4.44GNAGKK82 pKa = 10.4RR83 pKa = 11.84KK84 pKa = 7.9RR85 pKa = 11.84QRR87 pKa = 11.84RR88 pKa = 11.84RR89 pKa = 11.84RR90 pKa = 11.84KK91 pKa = 8.51KK92 pKa = 9.56KK93 pKa = 9.0AFKK96 pKa = 10.9RR97 pKa = 11.84MMTEE101 pKa = 3.5LEE103 pKa = 3.87DD104 pKa = 3.71RR105 pKa = 11.84FRR107 pKa = 11.84KK108 pKa = 10.15LFGTTSTTGDD118 pKa = 3.49STVDD122 pKa = 4.21SEE124 pKa = 5.45DD125 pKa = 3.73EE126 pKa = 4.08PPKK129 pKa = 10.29KK130 pKa = 9.89EE131 pKa = 4.93KK132 pKa = 10.59RR133 pKa = 11.84VDD135 pKa = 2.81WDD137 pKa = 3.95EE138 pKa = 3.78YY139 pKa = 9.66WNPEE143 pKa = 4.03EE144 pKa = 4.34IEE146 pKa = 4.24RR147 pKa = 11.84MLMDD151 pKa = 4.17

Molecular weight: 17.82 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q66014|Q66014_FIVPE Isoform of P16090 Env protein OS=Feline immunodeficiency virus (isolate Petaluma) OX=11674 GN=env PE=4 SV=1
MM1 pKa = 7.71LPRR4 pKa = 11.84NGDD7 pKa = 3.64FVPDD11 pKa = 4.64FIYY14 pKa = 10.72RR15 pKa = 11.84NNNIFTDD22 pKa = 3.86NQRR25 pKa = 11.84SGSMEE30 pKa = 3.88TSTISSPSRR39 pKa = 11.84RR40 pKa = 11.84IRR42 pKa = 11.84NNFLGLLGTRR52 pKa = 11.84RR53 pKa = 11.84TRR55 pKa = 11.84LSGLSWGNDD64 pKa = 3.14TSKK67 pKa = 11.14SS68 pKa = 3.55

Molecular weight: 7.72 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

1

7

2978

68

1124

425.4

48.43

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.111 ± 1.103

2.418 ± 0.636

4.13 ± 0.422

7.455 ± 0.614

2.888 ± 0.502

7.421 ± 0.442

1.276 ± 0.246

7.018 ± 0.958

7.455 ± 0.699

8.731 ± 0.368

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.989 ± 0.347

5.373 ± 0.637

5.037 ± 0.371

5.272 ± 0.463

5.541 ± 0.953

5.037 ± 0.459

4.835 ± 0.491

5.071 ± 0.334

2.686 ± 0.425

3.257 ± 0.355
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski