Amino acid dipepetide frequency for Flammeovirga pectinis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.83AlaAla: 3.83 ± 0.069	0.495AlaCys: 0.495 ± 0.016	3.329AlaAsp: 3.329 ± 0.041	3.748AlaGlu: 3.748 ± 0.053	3.069AlaPhe: 3.069 ± 0.05	3.765AlaGly: 3.765 ± 0.057	1.018AlaHis: 1.018 ± 0.027	4.796AlaIle: 4.796 ± 0.054	4.173AlaLys: 4.173 ± 0.059	5.754AlaLeu: 5.754 ± 0.066	1.439AlaMet: 1.439 ± 0.03	3.218AlaAsn: 3.218 ± 0.044	2.022AlaPro: 2.022 ± 0.044	2.391AlaGln: 2.391 ± 0.043	1.794AlaArg: 1.794 ± 0.029	4.131AlaSer: 4.131 ± 0.057	3.769AlaThr: 3.769 ± 0.06	3.757AlaVal: 3.757 ± 0.062	0.643AlaTrp: 0.643 ± 0.019	2.482AlaTyr: 2.482 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	0.414CysAla: 0.414 ± 0.019	0.086CysCys: 0.086 ± 0.008	0.417CysAsp: 0.417 ± 0.018	0.421CysGlu: 0.421 ± 0.019	0.38CysPhe: 0.38 ± 0.013	0.536CysGly: 0.536 ± 0.02	0.177CysHis: 0.177 ± 0.012	0.608CysIle: 0.608 ± 0.022	0.434CysLys: 0.434 ± 0.017	0.643CysLeu: 0.643 ± 0.019	0.136CysMet: 0.136 ± 0.009	0.42CysAsn: 0.42 ± 0.016	0.234CysPro: 0.234 ± 0.012	0.213CysGln: 0.213 ± 0.01	0.205CysArg: 0.205 ± 0.011	0.574CysSer: 0.574 ± 0.02	0.467CysThr: 0.467 ± 0.019	0.425CysVal: 0.425 ± 0.016	0.068CysTrp: 0.068 ± 0.006	0.277CysTyr: 0.277 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	3.617AspAla: 3.617 ± 0.046	0.377AspCys: 0.377 ± 0.015	3.04AspAsp: 3.04 ± 0.05	3.784AspGlu: 3.784 ± 0.05	3.31AspPhe: 3.31 ± 0.047	4.02AspGly: 4.02 ± 0.067	1.006AspHis: 1.006 ± 0.025	4.745AspIle: 4.745 ± 0.057	4.4AspLys: 4.4 ± 0.054	5.43AspLeu: 5.43 ± 0.057	1.182AspMet: 1.182 ± 0.028	3.625AspAsn: 3.625 ± 0.058	1.934AspPro: 1.934 ± 0.036	2.038AspGln: 2.038 ± 0.036	2.031AspArg: 2.031 ± 0.035	3.177AspSer: 3.177 ± 0.06	2.934AspThr: 2.934 ± 0.05	3.813AspVal: 3.813 ± 0.05	0.86AspTrp: 0.86 ± 0.023	2.75AspTyr: 2.75 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	4.11GluAla: 4.11 ± 0.064	0.344GluCys: 0.344 ± 0.014	3.809GluAsp: 3.809 ± 0.05	5.343GluGlu: 5.343 ± 0.07	2.806GluPhe: 2.806 ± 0.038	4.416GluGly: 4.416 ± 0.055	1.18GluHis: 1.18 ± 0.028	5.482GluIle: 5.482 ± 0.06	5.483GluLys: 5.483 ± 0.083	6.055GluLeu: 6.055 ± 0.064	1.643GluMet: 1.643 ± 0.03	4.549GluAsn: 4.549 ± 0.053	1.327GluPro: 1.327 ± 0.028	2.351GluGln: 2.351 ± 0.036	2.378GluArg: 2.378 ± 0.041	3.371GluSer: 3.371 ± 0.044	3.33GluThr: 3.33 ± 0.046	4.898GluVal: 4.898 ± 0.05	0.852GluTrp: 0.852 ± 0.022	2.743GluTyr: 2.743 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	2.689PheAla: 2.689 ± 0.039	0.416PheCys: 0.416 ± 0.016	3.406PheAsp: 3.406 ± 0.048	3.108PheGlu: 3.108 ± 0.041	2.586PhePhe: 2.586 ± 0.042	3.345PheGly: 3.345 ± 0.041	0.829PheHis: 0.829 ± 0.024	3.954PheIle: 3.954 ± 0.048	3.594PheLys: 3.594 ± 0.048	4.352PheLeu: 4.352 ± 0.059	1.092PheMet: 1.092 ± 0.028	3.238PheAsn: 3.238 ± 0.047	1.545PhePro: 1.545 ± 0.03	1.466PheGln: 1.466 ± 0.027	1.563PheArg: 1.563 ± 0.031	4.118PheSer: 4.118 ± 0.049	3.417PheThr: 3.417 ± 0.064	2.849PheVal: 2.849 ± 0.043	0.538PheTrp: 0.538 ± 0.016	2.226PheTyr: 2.226 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	4.176GlyAla: 4.176 ± 0.058	0.559GlyCys: 0.559 ± 0.025	3.683GlyAsp: 3.683 ± 0.049	4.037GlyGlu: 4.037 ± 0.057	3.332GlyPhe: 3.332 ± 0.048	4.699GlyGly: 4.699 ± 0.072	1.134GlyHis: 1.134 ± 0.026	5.274GlyIle: 5.274 ± 0.062	4.817GlyLys: 4.817 ± 0.068	5.503GlyLeu: 5.503 ± 0.066	1.592GlyMet: 1.592 ± 0.032	3.885GlyAsn: 3.885 ± 0.056	1.284GlyPro: 1.284 ± 0.028	2.079GlyGln: 2.079 ± 0.039	2.021GlyArg: 2.021 ± 0.036	3.976GlySer: 3.976 ± 0.066	4.114GlyThr: 4.114 ± 0.08	4.793GlyVal: 4.793 ± 0.065	0.86GlyTrp: 0.86 ± 0.026	3.056GlyTyr: 3.056 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	0.862HisAla: 0.862 ± 0.025	0.154HisCys: 0.154 ± 0.01	0.882HisAsp: 0.882 ± 0.024	1.001HisGlu: 1.001 ± 0.022	1.104HisPhe: 1.104 ± 0.024	1.08HisGly: 1.08 ± 0.027	0.475HisHis: 0.475 ± 0.016	1.335HisIle: 1.335 ± 0.024	1.165HisLys: 1.165 ± 0.029	1.834HisLeu: 1.834 ± 0.031	0.33HisMet: 0.33 ± 0.013	0.931HisAsn: 0.931 ± 0.02	0.836HisPro: 0.836 ± 0.022	0.761HisGln: 0.761 ± 0.023	0.628HisArg: 0.628 ± 0.018	1.145HisSer: 1.145 ± 0.031	0.999HisThr: 0.999 ± 0.026	0.915HisVal: 0.915 ± 0.021	0.243HisTrp: 0.243 ± 0.01	0.872HisTyr: 0.872 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.063IleAla: 5.063 ± 0.069	0.606IleCys: 0.606 ± 0.021	5.405IleAsp: 5.405 ± 0.062	5.549IleGlu: 5.549 ± 0.063	3.382IlePhe: 3.382 ± 0.048	5.277IleGly: 5.277 ± 0.055	1.429IleHis: 1.429 ± 0.029	5.919IleIle: 5.919 ± 0.063	5.62IleLys: 5.62 ± 0.066	6.506IleLeu: 6.506 ± 0.072	1.333IleMet: 1.333 ± 0.029	5.016IleAsn: 5.016 ± 0.073	3.035IlePro: 3.035 ± 0.042	2.595IleGln: 2.595 ± 0.038	2.426IleArg: 2.426 ± 0.037	6.029IleSer: 6.029 ± 0.066	5.28IleThr: 5.28 ± 0.073	4.531IleVal: 4.531 ± 0.049	0.738IleTrp: 0.738 ± 0.024	3.107IleTyr: 3.107 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	4.348LysAla: 4.348 ± 0.063	0.371LysCys: 0.371 ± 0.014	4.394LysAsp: 4.394 ± 0.06	6.449LysGlu: 6.449 ± 0.085	2.883LysPhe: 2.883 ± 0.044	4.959LysGly: 4.959 ± 0.061	1.244LysHis: 1.244 ± 0.026	5.623LysIle: 5.623 ± 0.066	6.651LysLys: 6.651 ± 0.096	6.118LysLeu: 6.118 ± 0.07	1.982LysMet: 1.982 ± 0.035	4.728LysAsn: 4.728 ± 0.064	2.118LysPro: 2.118 ± 0.038	2.436LysGln: 2.436 ± 0.041	2.669LysArg: 2.669 ± 0.044	4.606LysSer: 4.606 ± 0.065	3.896LysThr: 3.896 ± 0.048	5.179LysVal: 5.179 ± 0.065	0.887LysTrp: 0.887 ± 0.022	3.309LysTyr: 3.309 ± 0.057	0.0LysXaa: 0.0 ± 0.0
Leu	5.047LeuAla: 5.047 ± 0.053	0.683LeuCys: 0.683 ± 0.022	5.161LeuAsp: 5.161 ± 0.052	5.964LeuGlu: 5.964 ± 0.073	4.793LeuPhe: 4.793 ± 0.058	5.58LeuGly: 5.58 ± 0.063	1.523LeuHis: 1.523 ± 0.032	6.766LeuIle: 6.766 ± 0.069	7.006LeuLys: 7.006 ± 0.077	8.768LeuLeu: 8.768 ± 0.096	2.029LeuMet: 2.029 ± 0.035	5.398LeuAsn: 5.398 ± 0.064	3.635LeuPro: 3.635 ± 0.044	3.061LeuGln: 3.061 ± 0.045	3.007LeuArg: 3.007 ± 0.044	7.52LeuSer: 7.52 ± 0.076	5.377LeuThr: 5.377 ± 0.069	4.847LeuVal: 4.847 ± 0.052	0.889LeuTrp: 0.889 ± 0.027	3.318LeuTyr: 3.318 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	1.404MetAla: 1.404 ± 0.03	0.14MetCys: 0.14 ± 0.009	1.198MetAsp: 1.198 ± 0.026	1.318MetGlu: 1.318 ± 0.027	0.875MetPhe: 0.875 ± 0.023	1.425MetGly: 1.425 ± 0.033	0.433MetHis: 0.433 ± 0.016	1.607MetIle: 1.607 ± 0.036	2.08MetLys: 2.08 ± 0.036	1.938MetLeu: 1.938 ± 0.036	0.647MetMet: 0.647 ± 0.02	1.382MetAsn: 1.382 ± 0.028	0.818MetPro: 0.818 ± 0.022	0.788MetGln: 0.788 ± 0.018	0.862MetArg: 0.862 ± 0.021	1.538MetSer: 1.538 ± 0.03	1.241MetThr: 1.241 ± 0.026	1.257MetVal: 1.257 ± 0.029	0.233MetTrp: 0.233 ± 0.011	0.85MetTyr: 0.85 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.685AsnAla: 3.685 ± 0.052	0.414AsnCys: 0.414 ± 0.017	3.454AsnAsp: 3.454 ± 0.048	3.683AsnGlu: 3.683 ± 0.049	2.984AsnPhe: 2.984 ± 0.041	4.386AsnGly: 4.386 ± 0.072	1.088AsnHis: 1.088 ± 0.025	4.879AsnIle: 4.879 ± 0.073	4.526AsnLys: 4.526 ± 0.056	5.228AsnLeu: 5.228 ± 0.066	1.232AsnMet: 1.232 ± 0.026	4.17AsnAsn: 4.17 ± 0.082	2.434AsnPro: 2.434 ± 0.041	2.351AsnGln: 2.351 ± 0.037	1.916AsnArg: 1.916 ± 0.032	4.085AsnSer: 4.085 ± 0.067	3.944AsnThr: 3.944 ± 0.063	3.68AsnVal: 3.68 ± 0.051	0.862AsnTrp: 0.862 ± 0.023	3.005AsnTyr: 3.005 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	1.719ProAla: 1.719 ± 0.039	0.184ProCys: 0.184 ± 0.011	1.702ProAsp: 1.702 ± 0.025	2.322ProGlu: 2.322 ± 0.037	1.887ProPhe: 1.887 ± 0.036	1.617ProGly: 1.617 ± 0.032	0.62ProHis: 0.62 ± 0.017	2.702ProIle: 2.702 ± 0.039	2.378ProLys: 2.378 ± 0.045	2.982ProLeu: 2.982 ± 0.044	0.718ProMet: 0.718 ± 0.019	2.277ProAsn: 2.277 ± 0.038	0.841ProPro: 0.841 ± 0.028	1.163ProGln: 1.163 ± 0.026	0.9ProArg: 0.9 ± 0.022	2.699ProSer: 2.699 ± 0.042	2.216ProThr: 2.216 ± 0.038	2.173ProVal: 2.173 ± 0.042	0.363ProTrp: 0.363 ± 0.014	1.476ProTyr: 1.476 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	1.788GlnAla: 1.788 ± 0.033	0.171GlnCys: 0.171 ± 0.01	1.742GlnAsp: 1.742 ± 0.038	2.554GlnGlu: 2.554 ± 0.044	1.759GlnPhe: 1.759 ± 0.028	1.994GlnGly: 1.994 ± 0.038	0.613GlnHis: 0.613 ± 0.017	2.509GlnIle: 2.509 ± 0.04	2.954GlnLys: 2.954 ± 0.045	3.524GlnLeu: 3.524 ± 0.048	0.852GlnMet: 0.852 ± 0.022	2.15GlnAsn: 2.15 ± 0.039	1.014GlnPro: 1.014 ± 0.024	1.381GlnGln: 1.381 ± 0.036	1.222GlnArg: 1.222 ± 0.03	2.119GlnSer: 2.119 ± 0.034	1.752GlnThr: 1.752 ± 0.03	2.034GlnVal: 2.034 ± 0.034	0.426GlnTrp: 0.426 ± 0.014	1.461GlnTyr: 1.461 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	1.879ArgAla: 1.879 ± 0.032	0.198ArgCys: 0.198 ± 0.01	1.746ArgAsp: 1.746 ± 0.034	2.055ArgGlu: 2.055 ± 0.04	1.759ArgPhe: 1.759 ± 0.031	1.972ArgGly: 1.972 ± 0.043	0.54ArgHis: 0.54 ± 0.016	2.593ArgIle: 2.593 ± 0.039	2.638ArgLys: 2.638 ± 0.042	3.081ArgLeu: 3.081 ± 0.045	0.861ArgMet: 0.861 ± 0.024	1.959ArgAsn: 1.959 ± 0.032	1.067ArgPro: 1.067 ± 0.024	1.055ArgGln: 1.055 ± 0.026	1.273ArgArg: 1.273 ± 0.031	1.95ArgSer: 1.95 ± 0.034	1.834ArgThr: 1.834 ± 0.033	2.184ArgVal: 2.184 ± 0.033	0.425ArgTrp: 0.425 ± 0.016	1.487ArgTyr: 1.487 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	3.951SerAla: 3.951 ± 0.051	0.673SerCys: 0.673 ± 0.023	4.009SerAsp: 4.009 ± 0.066	4.151SerGlu: 4.151 ± 0.05	4.115SerPhe: 4.115 ± 0.054	4.383SerGly: 4.383 ± 0.072	1.109SerHis: 1.109 ± 0.026	6.205SerIle: 6.205 ± 0.08	4.843SerLys: 4.843 ± 0.055	6.474SerLeu: 6.474 ± 0.069	1.416SerMet: 1.416 ± 0.027	4.28SerAsn: 4.28 ± 0.063	2.181SerPro: 2.181 ± 0.032	2.028SerGln: 2.028 ± 0.037	2.069SerArg: 2.069 ± 0.032	5.486SerSer: 5.486 ± 0.074	4.509SerThr: 4.509 ± 0.071	4.118SerVal: 4.118 ± 0.055	0.787SerTrp: 0.787 ± 0.021	3.065SerTyr: 3.065 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	3.71ThrAla: 3.71 ± 0.054	0.341ThrCys: 0.341 ± 0.015	3.512ThrAsp: 3.512 ± 0.062	3.63ThrGlu: 3.63 ± 0.054	3.347ThrPhe: 3.347 ± 0.061	3.836ThrGly: 3.836 ± 0.067	0.991ThrHis: 0.991 ± 0.025	5.039ThrIle: 5.039 ± 0.074	3.794ThrLys: 3.794 ± 0.051	5.92ThrLeu: 5.92 ± 0.068	1.004ThrMet: 1.004 ± 0.025	3.362ThrAsn: 3.362 ± 0.059	2.623ThrPro: 2.623 ± 0.042	1.869ThrGln: 1.869 ± 0.032	1.556ThrArg: 1.556 ± 0.034	4.632ThrSer: 4.632 ± 0.069	4.063ThrThr: 4.063 ± 0.083	4.013ThrVal: 4.013 ± 0.074	0.709ThrTrp: 0.709 ± 0.024	2.664ThrTyr: 2.664 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.062ValAla: 4.062 ± 0.056	0.501ValCys: 0.501 ± 0.015	3.981ValAsp: 3.981 ± 0.05	4.238ValGlu: 4.238 ± 0.05	3.032ValPhe: 3.032 ± 0.039	4.049ValGly: 4.049 ± 0.053	1.011ValHis: 1.011 ± 0.021	4.946ValIle: 4.946 ± 0.057	4.334ValLys: 4.334 ± 0.062	5.407ValLeu: 5.407 ± 0.061	1.395ValMet: 1.395 ± 0.027	3.762ValAsn: 3.762 ± 0.048	2.155ValPro: 2.155 ± 0.036	1.879ValGln: 1.879 ± 0.036	2.031ValArg: 2.031 ± 0.039	4.567ValSer: 4.567 ± 0.062	3.986ValThr: 3.986 ± 0.069	4.241ValVal: 4.241 ± 0.052	0.659ValTrp: 0.659 ± 0.02	2.558ValTyr: 2.558 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.652TrpAla: 0.652 ± 0.018	0.098TrpCys: 0.098 ± 0.008	0.721TrpAsp: 0.721 ± 0.021	0.833TrpGlu: 0.833 ± 0.025	0.504TrpPhe: 0.504 ± 0.019	0.852TrpGly: 0.852 ± 0.024	0.256TrpHis: 0.256 ± 0.012	0.806TrpIle: 0.806 ± 0.02	0.86TrpLys: 0.86 ± 0.022	0.965TrpLeu: 0.965 ± 0.024	0.323TrpMet: 0.323 ± 0.015	0.79TrpAsn: 0.79 ± 0.023	0.259TrpPro: 0.259 ± 0.013	0.411TrpGln: 0.411 ± 0.016	0.424TrpArg: 0.424 ± 0.015	0.847TrpSer: 0.847 ± 0.021	0.64TrpThr: 0.64 ± 0.019	0.825TrpVal: 0.825 ± 0.022	0.168TrpTrp: 0.168 ± 0.009	0.518TrpTyr: 0.518 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.618TyrAla: 2.618 ± 0.039	0.325TyrCys: 0.325 ± 0.014	2.482TyrAsp: 2.482 ± 0.046	2.285TyrGlu: 2.285 ± 0.041	2.426TyrPhe: 2.426 ± 0.048	2.683TyrGly: 2.683 ± 0.045	0.876TyrHis: 0.876 ± 0.022	3.058TyrIle: 3.058 ± 0.042	3.098TyrLys: 3.098 ± 0.049	3.892TyrLeu: 3.892 ± 0.048	0.826TyrMet: 0.826 ± 0.022	2.865TyrAsn: 2.865 ± 0.057	1.577TyrPro: 1.577 ± 0.032	1.702TyrGln: 1.702 ± 0.037	1.58TyrArg: 1.58 ± 0.028	3.282TyrSer: 3.282 ± 0.054	2.846TyrThr: 2.846 ± 0.052	2.26TyrVal: 2.26 ± 0.036	0.543TyrTrp: 0.543 ± 0.019	2.083TyrTyr: 2.083 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4986 proteins (1933729 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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