Amino acid dipepetide frequency for Yoonia vestfoldensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.141AlaAla: 19.141 ± 0.202	1.167AlaCys: 1.167 ± 0.035	8.055AlaAsp: 8.055 ± 0.086	7.028AlaGlu: 7.028 ± 0.087	4.492AlaPhe: 4.492 ± 0.066	11.113AlaGly: 11.113 ± 0.115	2.474AlaHis: 2.474 ± 0.05	6.668AlaIle: 6.668 ± 0.067	3.955AlaLys: 3.955 ± 0.065	14.708AlaLeu: 14.708 ± 0.149	4.046AlaMet: 4.046 ± 0.064	2.93AlaAsn: 2.93 ± 0.059	5.922AlaPro: 5.922 ± 0.084	5.82AlaGln: 5.82 ± 0.083	8.96AlaArg: 8.96 ± 0.104	5.743AlaSer: 5.743 ± 0.079	6.53AlaThr: 6.53 ± 0.093	8.796AlaVal: 8.796 ± 0.106	1.471AlaTrp: 1.471 ± 0.037	2.645AlaTyr: 2.645 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.208CysAla: 1.208 ± 0.035	0.12CysCys: 0.12 ± 0.01	0.682CysAsp: 0.682 ± 0.025	0.411CysGlu: 0.411 ± 0.022	0.333CysPhe: 0.333 ± 0.019	0.94CysGly: 0.94 ± 0.028	0.263CysHis: 0.263 ± 0.014	0.44CysIle: 0.44 ± 0.022	0.208CysLys: 0.208 ± 0.013	0.856CysLeu: 0.856 ± 0.029	0.188CysMet: 0.188 ± 0.012	0.227CysAsn: 0.227 ± 0.014	0.497CysPro: 0.497 ± 0.022	0.267CysGln: 0.267 ± 0.016	0.533CysArg: 0.533 ± 0.02	0.428CysSer: 0.428 ± 0.021	0.454CysThr: 0.454 ± 0.02	0.628CysVal: 0.628 ± 0.021	0.107CysTrp: 0.107 ± 0.009	0.202CysTyr: 0.202 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.124AspAla: 8.124 ± 0.103	0.549AspCys: 0.549 ± 0.026	3.835AspAsp: 3.835 ± 0.077	2.946AspGlu: 2.946 ± 0.061	2.376AspPhe: 2.376 ± 0.043	5.355AspGly: 5.355 ± 0.085	1.672AspHis: 1.672 ± 0.04	3.43AspIle: 3.43 ± 0.055	1.739AspLys: 1.739 ± 0.049	7.037AspLeu: 7.037 ± 0.085	1.847AspMet: 1.847 ± 0.041	1.365AspAsn: 1.365 ± 0.036	3.808AspPro: 3.808 ± 0.057	2.378AspGln: 2.378 ± 0.049	4.535AspArg: 4.535 ± 0.067	2.344AspSer: 2.344 ± 0.042	2.977AspThr: 2.977 ± 0.055	4.39AspVal: 4.39 ± 0.07	1.268AspTrp: 1.268 ± 0.039	1.616AspTyr: 1.616 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.38GluAla: 6.38 ± 0.088	0.337GluCys: 0.337 ± 0.017	2.765GluAsp: 2.765 ± 0.055	2.377GluGlu: 2.377 ± 0.061	1.496GluPhe: 1.496 ± 0.04	3.431GluGly: 3.431 ± 0.061	0.882GluHis: 0.882 ± 0.03	3.355GluIle: 3.355 ± 0.054	1.781GluLys: 1.781 ± 0.049	4.298GluLeu: 4.298 ± 0.068	1.65GluMet: 1.65 ± 0.034	1.542GluAsn: 1.542 ± 0.039	2.06GluPro: 2.06 ± 0.042	1.73GluGln: 1.73 ± 0.038	3.339GluArg: 3.339 ± 0.062	1.867GluSer: 1.867 ± 0.038	3.4GluThr: 3.4 ± 0.063	3.632GluVal: 3.632 ± 0.062	0.552GluTrp: 0.552 ± 0.02	0.895GluTyr: 0.895 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	5.014PheAla: 5.014 ± 0.063	0.423PheCys: 0.423 ± 0.023	2.863PheAsp: 2.863 ± 0.044	1.886PheGlu: 1.886 ± 0.037	1.409PhePhe: 1.409 ± 0.038	3.588PheGly: 3.588 ± 0.057	0.732PheHis: 0.732 ± 0.027	1.786PheIle: 1.786 ± 0.04	0.896PheLys: 0.896 ± 0.028	3.226PheLeu: 3.226 ± 0.06	0.908PheMet: 0.908 ± 0.028	1.034PheAsn: 1.034 ± 0.029	1.425PhePro: 1.425 ± 0.032	1.039PheGln: 1.039 ± 0.028	2.048PheArg: 2.048 ± 0.045	1.936PheSer: 1.936 ± 0.048	2.109PheThr: 2.109 ± 0.04	2.73PheVal: 2.73 ± 0.053	0.581PheTrp: 0.581 ± 0.023	0.915PheTyr: 0.915 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.924GlyAla: 9.924 ± 0.102	0.824GlyCys: 0.824 ± 0.028	4.767GlyAsp: 4.767 ± 0.071	3.736GlyGlu: 3.736 ± 0.063	3.638GlyPhe: 3.638 ± 0.052	6.979GlyGly: 6.979 ± 0.1	1.855GlyHis: 1.855 ± 0.04	4.695GlyIle: 4.695 ± 0.062	2.959GlyLys: 2.959 ± 0.064	9.089GlyLeu: 9.089 ± 0.095	2.542GlyMet: 2.542 ± 0.051	2.055GlyAsn: 2.055 ± 0.049	3.585GlyPro: 3.585 ± 0.059	3.488GlyGln: 3.488 ± 0.055	5.496GlyArg: 5.496 ± 0.084	4.013GlySer: 4.013 ± 0.062	4.667GlyThr: 4.667 ± 0.073	6.168GlyVal: 6.168 ± 0.071	1.408GlyTrp: 1.408 ± 0.035	2.264GlyTyr: 2.264 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.447HisAla: 2.447 ± 0.045	0.248HisCys: 0.248 ± 0.016	1.484HisAsp: 1.484 ± 0.039	0.891HisGlu: 0.891 ± 0.028	0.811HisPhe: 0.811 ± 0.025	1.923HisGly: 1.923 ± 0.046	0.622HisHis: 0.622 ± 0.029	1.072HisIle: 1.072 ± 0.03	0.555HisLys: 0.555 ± 0.024	2.288HisLeu: 2.288 ± 0.043	0.538HisMet: 0.538 ± 0.022	0.47HisAsn: 0.47 ± 0.021	1.373HisPro: 1.373 ± 0.037	0.657HisGln: 0.657 ± 0.025	1.31HisArg: 1.31 ± 0.031	0.907HisSer: 0.907 ± 0.029	0.752HisThr: 0.752 ± 0.026	1.521HisVal: 1.521 ± 0.034	0.374HisTrp: 0.374 ± 0.018	0.549HisTyr: 0.549 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	8.234IleAla: 8.234 ± 0.093	0.694IleCys: 0.694 ± 0.023	3.69IleAsp: 3.69 ± 0.052	2.977IleGlu: 2.977 ± 0.05	1.8IlePhe: 1.8 ± 0.042	5.326IleGly: 5.326 ± 0.075	0.974IleHis: 0.974 ± 0.028	2.862IleIle: 2.862 ± 0.053	1.594IleLys: 1.594 ± 0.043	4.93IleLeu: 4.93 ± 0.081	1.299IleMet: 1.299 ± 0.038	1.563IleAsn: 1.563 ± 0.039	2.411IlePro: 2.411 ± 0.039	1.224IleGln: 1.224 ± 0.035	3.314IleArg: 3.314 ± 0.055	3.044IleSer: 3.044 ± 0.057	3.535IleThr: 3.535 ± 0.054	3.97IleVal: 3.97 ± 0.066	0.796IleTrp: 0.796 ± 0.023	1.308IleTyr: 1.308 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	3.84LysAla: 3.84 ± 0.063	0.19LysCys: 0.19 ± 0.014	1.784LysAsp: 1.784 ± 0.047	1.228LysGlu: 1.228 ± 0.038	0.832LysPhe: 0.832 ± 0.029	2.519LysGly: 2.519 ± 0.06	0.59LysHis: 0.59 ± 0.022	1.73LysIle: 1.73 ± 0.038	1.066LysLys: 1.066 ± 0.036	2.901LysLeu: 2.901 ± 0.055	0.836LysMet: 0.836 ± 0.025	0.734LysAsn: 0.734 ± 0.028	1.691LysPro: 1.691 ± 0.043	0.94LysGln: 0.94 ± 0.032	2.118LysArg: 2.118 ± 0.044	1.798LysSer: 1.798 ± 0.043	1.977LysThr: 1.977 ± 0.045	2.124LysVal: 2.124 ± 0.052	0.373LysTrp: 0.373 ± 0.017	0.582LysTyr: 0.582 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.814LeuAla: 13.814 ± 0.163	0.999LeuCys: 0.999 ± 0.032	6.414LeuAsp: 6.414 ± 0.073	4.351LeuGlu: 4.351 ± 0.069	3.391LeuPhe: 3.391 ± 0.064	8.483LeuGly: 8.483 ± 0.098	2.046LeuHis: 2.046 ± 0.039	5.524LeuIle: 5.524 ± 0.077	2.734LeuLys: 2.734 ± 0.057	8.969LeuLeu: 8.969 ± 0.124	2.625LeuMet: 2.625 ± 0.047	2.538LeuAsn: 2.538 ± 0.04	5.716LeuPro: 5.716 ± 0.077	3.393LeuGln: 3.393 ± 0.054	7.77LeuArg: 7.77 ± 0.107	6.046LeuSer: 6.046 ± 0.084	6.186LeuThr: 6.186 ± 0.083	6.988LeuVal: 6.988 ± 0.098	1.314LeuTrp: 1.314 ± 0.039	1.896LeuTyr: 1.896 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	3.793MetAla: 3.793 ± 0.056	0.186MetCys: 0.186 ± 0.013	1.474MetAsp: 1.474 ± 0.042	1.123MetGlu: 1.123 ± 0.033	0.82MetPhe: 0.82 ± 0.026	2.208MetGly: 2.208 ± 0.044	0.487MetHis: 0.487 ± 0.021	1.816MetIle: 1.816 ± 0.041	0.991MetLys: 0.991 ± 0.03	2.829MetLeu: 2.829 ± 0.054	0.838MetMet: 0.838 ± 0.025	0.852MetAsn: 0.852 ± 0.028	1.651MetPro: 1.651 ± 0.037	1.196MetGln: 1.196 ± 0.031	1.895MetArg: 1.895 ± 0.04	1.601MetSer: 1.601 ± 0.042	2.299MetThr: 2.299 ± 0.041	1.868MetVal: 1.868 ± 0.043	0.221MetTrp: 0.221 ± 0.012	0.351MetTyr: 0.351 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.325AsnAla: 3.325 ± 0.056	0.228AsnCys: 0.228 ± 0.014	1.551AsnAsp: 1.551 ± 0.04	1.062AsnGlu: 1.062 ± 0.035	0.938AsnPhe: 0.938 ± 0.026	2.279AsnGly: 2.279 ± 0.047	0.51AsnHis: 0.51 ± 0.019	1.567AsnIle: 1.567 ± 0.041	0.653AsnLys: 0.653 ± 0.024	2.591AsnLeu: 2.591 ± 0.05	0.704AsnMet: 0.704 ± 0.025	0.713AsnAsn: 0.713 ± 0.026	1.852AsnPro: 1.852 ± 0.039	0.704AsnGln: 0.704 ± 0.026	1.687AsnArg: 1.687 ± 0.035	1.088AsnSer: 1.088 ± 0.032	1.347AsnThr: 1.347 ± 0.038	1.849AsnVal: 1.849 ± 0.046	0.414AsnTrp: 0.414 ± 0.019	0.612AsnTyr: 0.612 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.704ProAla: 6.704 ± 0.091	0.37ProCys: 0.37 ± 0.018	4.194ProAsp: 4.194 ± 0.069	3.121ProGlu: 3.121 ± 0.053	1.971ProPhe: 1.971 ± 0.043	4.028ProGly: 4.028 ± 0.059	1.063ProHis: 1.063 ± 0.031	2.194ProIle: 2.194 ± 0.044	1.529ProLys: 1.529 ± 0.042	4.657ProLeu: 4.657 ± 0.067	1.334ProMet: 1.334 ± 0.034	1.199ProAsn: 1.199 ± 0.029	2.327ProPro: 2.327 ± 0.057	1.993ProGln: 1.993 ± 0.042	2.873ProArg: 2.873 ± 0.052	2.356ProSer: 2.356 ± 0.047	2.348ProThr: 2.348 ± 0.047	4.34ProVal: 4.34 ± 0.068	0.64ProTrp: 0.64 ± 0.023	1.163ProTyr: 1.163 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.878GlnAla: 4.878 ± 0.071	0.218GlnCys: 0.218 ± 0.012	2.197GlnAsp: 2.197 ± 0.048	1.416GlnGlu: 1.416 ± 0.034	1.161GlnPhe: 1.161 ± 0.03	3.015GlnGly: 3.015 ± 0.05	0.727GlnHis: 0.727 ± 0.028	2.557GlnIle: 2.557 ± 0.048	1.074GlnLys: 1.074 ± 0.03	3.232GlnLeu: 3.232 ± 0.055	1.297GlnMet: 1.297 ± 0.032	0.997GlnAsn: 0.997 ± 0.028	1.789GlnPro: 1.789 ± 0.036	1.39GlnGln: 1.39 ± 0.036	2.493GlnArg: 2.493 ± 0.051	2.002GlnSer: 2.002 ± 0.038	2.231GlnThr: 2.231 ± 0.045	2.621GlnVal: 2.621 ± 0.051	0.401GlnTrp: 0.401 ± 0.019	0.621GlnTyr: 0.621 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.502ArgAla: 8.502 ± 0.093	0.509ArgCys: 0.509 ± 0.021	4.574ArgAsp: 4.574 ± 0.068	3.026ArgGlu: 3.026 ± 0.061	2.611ArgPhe: 2.611 ± 0.051	4.442ArgGly: 4.442 ± 0.069	1.593ArgHis: 1.593 ± 0.04	3.997ArgIle: 3.997 ± 0.062	2.241ArgLys: 2.241 ± 0.045	7.345ArgLeu: 7.345 ± 0.095	2.03ArgMet: 2.03 ± 0.036	1.847ArgAsn: 1.847 ± 0.04	3.181ArgPro: 3.181 ± 0.054	2.575ArgGln: 2.575 ± 0.054	4.871ArgArg: 4.871 ± 0.08	3.351ArgSer: 3.351 ± 0.059	2.697ArgThr: 2.697 ± 0.051	4.411ArgVal: 4.411 ± 0.063	0.949ArgTrp: 0.949 ± 0.027	1.533ArgTyr: 1.533 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.07SerAla: 6.07 ± 0.083	0.46SerCys: 0.46 ± 0.02	3.284SerAsp: 3.284 ± 0.053	2.389SerGlu: 2.389 ± 0.054	2.229SerPhe: 2.229 ± 0.044	4.977SerGly: 4.977 ± 0.067	1.001SerHis: 1.001 ± 0.03	2.498SerIle: 2.498 ± 0.053	1.369SerLys: 1.369 ± 0.039	4.794SerLeu: 4.794 ± 0.058	1.32SerMet: 1.32 ± 0.028	1.331SerAsn: 1.331 ± 0.035	2.381SerPro: 2.381 ± 0.037	1.65SerGln: 1.65 ± 0.04	3.02SerArg: 3.02 ± 0.056	2.436SerSer: 2.436 ± 0.05	2.496SerThr: 2.496 ± 0.053	3.673SerVal: 3.673 ± 0.065	0.657SerTrp: 0.657 ± 0.028	1.302SerTyr: 1.302 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	7.066ThrAla: 7.066 ± 0.102	0.494ThrCys: 0.494 ± 0.021	3.259ThrAsp: 3.259 ± 0.057	2.581ThrGlu: 2.581 ± 0.051	2.008ThrPhe: 2.008 ± 0.048	5.617ThrGly: 5.617 ± 0.076	1.148ThrHis: 1.148 ± 0.03	3.143ThrIle: 3.143 ± 0.058	1.613ThrLys: 1.613 ± 0.047	6.088ThrLeu: 6.088 ± 0.077	1.367ThrMet: 1.367 ± 0.034	1.371ThrAsn: 1.371 ± 0.038	3.43ThrPro: 3.43 ± 0.052	1.964ThrGln: 1.964 ± 0.04	3.54ThrArg: 3.54 ± 0.057	2.824ThrSer: 2.824 ± 0.053	3.226ThrThr: 3.226 ± 0.068	3.715ThrVal: 3.715 ± 0.064	0.677ThrTrp: 0.677 ± 0.025	1.278ThrTyr: 1.278 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	9.048ValAla: 9.048 ± 0.095	0.598ValCys: 0.598 ± 0.02	4.218ValAsp: 4.218 ± 0.061	3.564ValGlu: 3.564 ± 0.074	2.824ValPhe: 2.824 ± 0.047	4.935ValGly: 4.935 ± 0.07	1.284ValHis: 1.284 ± 0.036	4.525ValIle: 4.525 ± 0.064	1.927ValLys: 1.927 ± 0.049	7.493ValLeu: 7.493 ± 0.091	2.256ValMet: 2.256 ± 0.045	1.971ValAsn: 1.971 ± 0.045	3.511ValPro: 3.511 ± 0.061	2.456ValGln: 2.456 ± 0.046	3.813ValArg: 3.813 ± 0.065	3.817ValSer: 3.817 ± 0.056	5.238ValThr: 5.238 ± 0.085	5.473ValVal: 5.473 ± 0.08	0.912ValTrp: 0.912 ± 0.029	1.441ValTyr: 1.441 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.442TrpAla: 1.442 ± 0.038	0.155TrpCys: 0.155 ± 0.01	0.859TrpAsp: 0.859 ± 0.028	0.561TrpGlu: 0.561 ± 0.021	0.553TrpPhe: 0.553 ± 0.021	0.957TrpGly: 0.957 ± 0.033	0.332TrpHis: 0.332 ± 0.016	0.671TrpIle: 0.671 ± 0.025	0.392TrpLys: 0.392 ± 0.019	1.573TrpLeu: 1.573 ± 0.045	0.409TrpMet: 0.409 ± 0.021	0.387TrpAsn: 0.387 ± 0.02	0.709TrpPro: 0.709 ± 0.026	0.667TrpGln: 0.667 ± 0.022	1.118TrpArg: 1.118 ± 0.032	0.698TrpSer: 0.698 ± 0.025	0.78TrpThr: 0.78 ± 0.024	0.941TrpVal: 0.941 ± 0.027	0.242TrpTrp: 0.242 ± 0.016	0.253TrpTyr: 0.253 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.711TyrAla: 2.711 ± 0.05	0.221TyrCys: 0.221 ± 0.013	1.64TyrAsp: 1.64 ± 0.037	1.096TyrGlu: 1.096 ± 0.034	0.855TyrPhe: 0.855 ± 0.029	2.036TyrGly: 2.036 ± 0.042	0.539TyrHis: 0.539 ± 0.022	1.017TyrIle: 1.017 ± 0.028	0.577TyrLys: 0.577 ± 0.023	2.292TyrLeu: 2.292 ± 0.043	0.466TyrMet: 0.466 ± 0.02	0.551TyrAsn: 0.551 ± 0.025	1.085TyrPro: 1.085 ± 0.032	0.787TyrGln: 0.787 ± 0.024	1.553TyrArg: 1.553 ± 0.04	1.04TyrSer: 1.04 ± 0.031	1.156TyrThr: 1.156 ± 0.029	1.464TyrVal: 1.464 ± 0.034	0.341TyrTrp: 0.341 ± 0.017	0.555TyrTyr: 0.555 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3889 proteins (1188150 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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