Amino acid dipepetide frequency for Simian T-cell lymphotropic virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.421AlaAla: 5.421 ± 1.771
2.464AlaCys: 2.464 ± 0.719
0.986AlaAsp: 0.986 ± 0.866
1.479AlaGlu: 1.479 ± 1.479
3.45AlaPhe: 3.45 ± 1.619
3.943AlaGly: 3.943 ± 1.069
1.479AlaHis: 1.479 ± 0.902
4.436AlaIle: 4.436 ± 1.375
1.971AlaLys: 1.971 ± 0.659
13.307AlaLeu: 13.307 ± 0.963
0.0AlaMet: 0.0 ± 0.0
1.479AlaAsn: 1.479 ± 0.902
7.393AlaPro: 7.393 ± 2.428
4.436AlaGln: 4.436 ± 0.68
2.464AlaArg: 2.464 ± 1.376
6.9AlaSer: 6.9 ± 2.069
2.464AlaThr: 2.464 ± 0.634
2.957AlaVal: 2.957 ± 1.264
0.986AlaTrp: 0.986 ± 0.474
1.971AlaTyr: 1.971 ± 0.948
0.0AlaXaa: 0.0 ± 0.0
Cys
0.493CysAla: 0.493 ± 0.493
0.493CysCys: 0.493 ± 0.47
0.493CysAsp: 0.493 ± 0.349
0.0CysGlu: 0.0 ± 0.0
0.986CysPhe: 0.986 ± 0.573
1.479CysGly: 1.479 ± 0.329
0.0CysHis: 0.0 ± 0.0
1.479CysIle: 1.479 ± 0.776
1.479CysLys: 1.479 ± 0.554
2.464CysLeu: 2.464 ± 0.719
0.493CysMet: 0.493 ± 0.47
0.986CysAsn: 0.986 ± 0.376
4.436CysPro: 4.436 ± 1.029
2.957CysGln: 2.957 ± 1.307
0.986CysArg: 0.986 ± 0.699
1.971CysSer: 1.971 ± 0.658
2.464CysThr: 2.464 ± 0.506
0.493CysVal: 0.493 ± 0.349
0.0CysTrp: 0.0 ± 0.0
0.493CysTyr: 0.493 ± 0.47
0.0CysXaa: 0.0 ± 0.0
Asp
0.986AspAla: 0.986 ± 0.376
0.986AspCys: 0.986 ± 0.986
0.986AspAsp: 0.986 ± 0.699
0.0AspGlu: 0.0 ± 0.0
0.986AspPhe: 0.986 ± 0.474
0.986AspGly: 0.986 ± 0.699
1.971AspHis: 1.971 ± 1.398
0.986AspIle: 0.986 ± 0.376
1.971AspLys: 1.971 ± 0.365
8.871AspLeu: 8.871 ± 1.072
0.0AspMet: 0.0 ± 0.0
0.986AspAsn: 0.986 ± 0.474
4.436AspPro: 4.436 ± 0.956
1.971AspGln: 1.971 ± 0.752
0.986AspArg: 0.986 ± 0.954
1.971AspSer: 1.971 ± 0.846
2.464AspThr: 2.464 ± 1.939
1.479AspVal: 1.479 ± 0.727
0.0AspTrp: 0.0 ± 0.0
0.493AspTyr: 0.493 ± 0.493
0.0AspXaa: 0.0 ± 0.0
Glu
2.957GluAla: 2.957 ± 0.639
0.493GluCys: 0.493 ± 0.493
0.493GluAsp: 0.493 ± 0.752
1.479GluGlu: 1.479 ± 1.479
1.479GluPhe: 1.479 ± 0.671
0.986GluGly: 0.986 ± 0.474
1.479GluHis: 1.479 ± 0.727
0.986GluIle: 0.986 ± 0.986
0.986GluLys: 0.986 ± 0.474
2.464GluLeu: 2.464 ± 1.142
0.493GluMet: 0.493 ± 0.493
0.493GluAsn: 0.493 ± 0.493
4.929GluPro: 4.929 ± 1.247
1.479GluGln: 1.479 ± 0.776
1.971GluArg: 1.971 ± 0.365
0.986GluSer: 0.986 ± 0.699
2.957GluThr: 2.957 ± 0.569
1.971GluVal: 1.971 ± 1.268
0.493GluTrp: 0.493 ± 0.752
0.986GluTyr: 0.986 ± 0.474
0.0GluXaa: 0.0 ± 0.0
Phe
1.479PheAla: 1.479 ± 0.654
0.986PheCys: 0.986 ± 0.699
1.479PheAsp: 1.479 ± 1.191
0.493PheGlu: 0.493 ± 0.349
1.479PhePhe: 1.479 ± 0.727
0.0PheGly: 0.0 ± 0.0
1.479PheHis: 1.479 ± 0.671
0.493PheIle: 0.493 ± 0.349
1.479PheLys: 1.479 ± 0.669
4.436PheLeu: 4.436 ± 0.973
0.493PheMet: 0.493 ± 0.493
0.0PheAsn: 0.0 ± 0.0
2.957PhePro: 2.957 ± 0.823
1.971PheGln: 1.971 ± 1.398
0.986PheArg: 0.986 ± 0.866
3.45PheSer: 3.45 ± 1.235
0.986PheThr: 0.986 ± 0.376
0.986PheVal: 0.986 ± 0.474
0.493PheTrp: 0.493 ± 0.47
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.436GlyAla: 4.436 ± 1.599
0.0GlyCys: 0.0 ± 0.0
0.986GlyAsp: 0.986 ± 0.699
2.464GlyGlu: 2.464 ± 0.86
0.986GlyPhe: 0.986 ± 0.62
4.436GlyGly: 4.436 ± 2.763
3.45GlyHis: 3.45 ± 1.619
2.464GlyIle: 2.464 ± 1.688
3.943GlyLys: 3.943 ± 1.305
10.35GlyLeu: 10.35 ± 0.389
0.493GlyMet: 0.493 ± 0.306
1.971GlyAsn: 1.971 ± 0.659
8.379GlyPro: 8.379 ± 1.948
1.971GlyGln: 1.971 ± 0.96
2.464GlyArg: 2.464 ± 1.175
3.943GlySer: 3.943 ± 0.893
1.971GlyThr: 1.971 ± 0.365
0.493GlyVal: 0.493 ± 0.47
0.493GlyTrp: 0.493 ± 0.47
1.971GlyTyr: 1.971 ± 1.145
0.0GlyXaa: 0.0 ± 0.0
His
1.971HisAla: 1.971 ± 1.398
1.479HisCys: 1.479 ± 0.554
1.479HisAsp: 1.479 ± 0.671
0.986HisGlu: 0.986 ± 0.699
1.479HisPhe: 1.479 ± 0.554
2.464HisGly: 2.464 ± 1.279
4.929HisHis: 4.929 ± 2.558
2.957HisIle: 2.957 ± 1.505
1.479HisLys: 1.479 ± 0.554
3.943HisLeu: 3.943 ± 1.104
0.986HisMet: 0.986 ± 0.699
1.479HisAsn: 1.479 ± 1.048
3.45HisPro: 3.45 ± 1.948
1.971HisGln: 1.971 ± 0.749
1.971HisArg: 1.971 ± 0.96
1.971HisSer: 1.971 ± 0.659
3.943HisThr: 3.943 ± 1.771
2.464HisVal: 2.464 ± 0.879
2.957HisTrp: 2.957 ± 1.116
0.493HisTyr: 0.493 ± 0.349
0.0HisXaa: 0.0 ± 0.0
Ile
0.986IleAla: 0.986 ± 0.573
0.0IleCys: 0.0 ± 0.0
3.45IleAsp: 3.45 ± 0.409
0.493IleGlu: 0.493 ± 0.349
0.986IlePhe: 0.986 ± 0.699
0.986IleGly: 0.986 ± 1.505
2.464IleHis: 2.464 ± 1.17
3.45IleIle: 3.45 ± 1.693
2.464IleLys: 2.464 ± 0.719
5.914IleLeu: 5.914 ± 0.344
0.493IleMet: 0.493 ± 0.493
0.986IleAsn: 0.986 ± 0.699
4.436IlePro: 4.436 ± 1.217
1.971IleGln: 1.971 ± 0.365
1.971IleArg: 1.971 ± 0.365
4.929IleSer: 4.929 ± 1.539
3.45IleThr: 3.45 ± 1.488
2.957IleVal: 2.957 ± 0.658
0.493IleTrp: 0.493 ± 0.349
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.45LysAla: 3.45 ± 1.293
0.986LysCys: 0.986 ± 0.94
2.957LysAsp: 2.957 ± 1.246
1.479LysGlu: 1.479 ± 0.902
0.493LysPhe: 0.493 ± 0.349
1.971LysGly: 1.971 ± 0.96
0.986LysHis: 0.986 ± 0.699
0.493LysIle: 0.493 ± 0.349
2.464LysLys: 2.464 ± 1.142
2.464LysLeu: 2.464 ± 1.787
0.493LysMet: 0.493 ± 0.47
2.957LysAsn: 2.957 ± 1.145
3.45LysPro: 3.45 ± 1.386
0.986LysGln: 0.986 ± 0.474
1.479LysArg: 1.479 ± 0.671
0.493LysSer: 0.493 ± 0.349
5.421LysThr: 5.421 ± 1.162
2.464LysVal: 2.464 ± 0.86
0.986LysTrp: 0.986 ± 0.699
0.986LysTyr: 0.986 ± 0.699
0.0LysXaa: 0.0 ± 0.0
Leu
9.364LeuAla: 9.364 ± 1.624
3.45LeuCys: 3.45 ± 0.6
4.436LeuAsp: 4.436 ± 0.654
3.45LeuGlu: 3.45 ± 1.297
2.464LeuPhe: 2.464 ± 0.88
6.9LeuGly: 6.9 ± 1.427
7.393LeuHis: 7.393 ± 3.566
6.9LeuIle: 6.9 ± 0.431
3.943LeuLys: 3.943 ± 1.25
17.25LeuLeu: 17.25 ± 1.293
0.493LeuMet: 0.493 ± 0.418
6.407LeuAsn: 6.407 ± 1.683
13.8LeuPro: 13.8 ± 3.95
14.786LeuGln: 14.786 ± 1.758
7.886LeuArg: 7.886 ± 1.898
6.407LeuSer: 6.407 ± 1.849
9.364LeuThr: 9.364 ± 2.522
5.914LeuVal: 5.914 ± 0.998
1.971LeuTrp: 1.971 ± 0.659
2.957LeuTyr: 2.957 ± 1.264
0.0LeuXaa: 0.0 ± 0.0
Met
0.493MetAla: 0.493 ± 0.493
0.0MetCys: 0.0 ± 0.0
0.493MetAsp: 0.493 ± 0.349
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.986MetGly: 0.986 ± 0.573
0.986MetHis: 0.986 ± 0.474
0.0MetIle: 0.0 ± 0.0
0.493MetLys: 0.493 ± 0.493
0.986MetLeu: 0.986 ± 0.573
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.464MetPro: 2.464 ± 1.175
0.493MetGln: 0.493 ± 0.493
0.493MetArg: 0.493 ± 0.349
0.986MetSer: 0.986 ± 0.62
0.0MetThr: 0.0 ± 0.0
0.493MetVal: 0.493 ± 0.47
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.971AsnAla: 1.971 ± 0.659
0.493AsnCys: 0.493 ± 0.349
0.0AsnAsp: 0.0 ± 0.0
0.986AsnGlu: 0.986 ± 0.62
0.986AsnPhe: 0.986 ± 0.573
1.971AsnGly: 1.971 ± 0.96
2.464AsnHis: 2.464 ± 1.17
3.45AsnIle: 3.45 ± 1.045
0.493AsnLys: 0.493 ± 0.493
0.986AsnLeu: 0.986 ± 0.954
0.986AsnMet: 0.986 ± 0.645
1.971AsnAsn: 1.971 ± 0.365
3.943AsnPro: 3.943 ± 0.912
0.986AsnGln: 0.986 ± 0.699
0.493AsnArg: 0.493 ± 0.47
2.957AsnSer: 2.957 ± 0.758
1.479AsnThr: 1.479 ± 0.329
1.479AsnVal: 1.479 ± 0.329
0.493AsnTrp: 0.493 ± 0.47
0.986AsnTyr: 0.986 ± 0.94
0.0AsnXaa: 0.0 ± 0.0
Pro
8.871ProAla: 8.871 ± 2.54
4.436ProCys: 4.436 ± 1.121
3.45ProAsp: 3.45 ± 1.846
4.929ProGlu: 4.929 ± 1.852
1.971ProPhe: 1.971 ± 1.055
9.364ProGly: 9.364 ± 1.808
2.464ProHis: 2.464 ± 1.17
3.943ProIle: 3.943 ± 0.912
2.957ProLys: 2.957 ± 1.804
13.307ProLeu: 13.307 ± 3.206
0.986ProMet: 0.986 ± 0.736
1.479ProAsn: 1.479 ± 0.554
12.321ProPro: 12.321 ± 2.875
7.393ProGln: 7.393 ± 0.802
4.436ProArg: 4.436 ± 1.251
8.871ProSer: 8.871 ± 2.674
5.914ProThr: 5.914 ± 0.477
8.379ProVal: 8.379 ± 1.313
2.957ProTrp: 2.957 ± 0.956
3.45ProTyr: 3.45 ± 0.6
0.0ProXaa: 0.0 ± 0.0
Gln
10.35GlnAla: 10.35 ± 1.503
1.971GlnCys: 1.971 ± 1.268
0.986GlnAsp: 0.986 ± 0.866
4.436GlnGlu: 4.436 ± 1.121
1.971GlnPhe: 1.971 ± 1.731
3.943GlnGly: 3.943 ± 0.55
1.971GlnHis: 1.971 ± 1.398
1.479GlnIle: 1.479 ± 1.048
1.971GlnLys: 1.971 ± 0.365
7.393GlnLeu: 7.393 ± 1.623
0.493GlnMet: 0.493 ± 0.493
1.479GlnAsn: 1.479 ± 1.41
6.9GlnPro: 6.9 ± 1.292
4.436GlnGln: 4.436 ± 1.251
2.464GlnArg: 2.464 ± 0.88
2.464GlnSer: 2.464 ± 0.506
3.943GlnThr: 3.943 ± 1.21
1.479GlnVal: 1.479 ± 0.727
1.479GlnTrp: 1.479 ± 0.554
1.971GlnTyr: 1.971 ± 0.658
0.0GlnXaa: 0.0 ± 0.0
Arg
3.943ArgAla: 3.943 ± 1.036
1.479ArgCys: 1.479 ± 0.979
2.464ArgAsp: 2.464 ± 1.404
1.971ArgGlu: 1.971 ± 0.365
2.464ArgPhe: 2.464 ± 0.634
5.914ArgGly: 5.914 ± 0.744
0.493ArgHis: 0.493 ± 0.349
0.0ArgIle: 0.0 ± 0.0
0.986ArgLys: 0.986 ± 0.474
4.929ArgLeu: 4.929 ± 0.966
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
5.421ArgPro: 5.421 ± 2.477
0.986ArgGln: 0.986 ± 0.376
4.929ArgArg: 4.929 ± 2.574
1.971ArgSer: 1.971 ± 0.365
3.45ArgThr: 3.45 ± 1.772
2.464ArgVal: 2.464 ± 1.464
0.986ArgTrp: 0.986 ± 0.699
1.479ArgTyr: 1.479 ± 1.048
0.0ArgXaa: 0.0 ± 0.0
Ser
4.929SerAla: 4.929 ± 1.228
1.479SerCys: 1.479 ± 0.727
2.957SerAsp: 2.957 ± 1.129
1.971SerGlu: 1.971 ± 0.658
1.479SerPhe: 1.479 ± 0.669
3.45SerGly: 3.45 ± 1.51
4.436SerHis: 4.436 ± 1.393
1.479SerIle: 1.479 ± 0.776
3.45SerLys: 3.45 ± 1.235
13.307SerLeu: 13.307 ± 2.844
0.493SerMet: 0.493 ± 0.493
1.971SerAsn: 1.971 ± 1.35
8.871SerPro: 8.871 ± 1.072
4.436SerGln: 4.436 ± 1.849
3.45SerArg: 3.45 ± 1.045
7.886SerSer: 7.886 ± 1.887
4.436SerThr: 4.436 ± 0.973
3.943SerVal: 3.943 ± 2.189
1.971SerTrp: 1.971 ± 1.35
0.986SerTyr: 0.986 ± 0.94
0.0SerXaa: 0.0 ± 0.0
Thr
1.479ThrAla: 1.479 ± 0.329
0.986ThrCys: 0.986 ± 0.376
2.957ThrAsp: 2.957 ± 0.919
0.986ThrGlu: 0.986 ± 0.474
0.493ThrPhe: 0.493 ± 0.349
4.929ThrGly: 4.929 ± 1.872
4.436ThrHis: 4.436 ± 0.107
4.436ThrIle: 4.436 ± 1.014
1.479ThrLys: 1.479 ± 0.979
9.857ThrLeu: 9.857 ± 3.868
0.0ThrMet: 0.0 ± 0.0
2.957ThrAsn: 2.957 ± 0.956
10.35ThrPro: 10.35 ± 1.076
3.943ThrGln: 3.943 ± 0.379
3.943ThrArg: 3.943 ± 0.767
4.436ThrSer: 4.436 ± 1.557
4.929ThrThr: 4.929 ± 1.407
2.464ThrVal: 2.464 ± 0.703
1.479ThrTrp: 1.479 ± 0.776
1.479ThrTyr: 1.479 ± 0.776
0.0ThrXaa: 0.0 ± 0.0
Val
2.464ValAla: 2.464 ± 0.506
1.479ValCys: 1.479 ± 0.554
0.986ValAsp: 0.986 ± 0.376
1.971ValGlu: 1.971 ± 0.948
0.986ValPhe: 0.986 ± 0.376
1.479ValGly: 1.479 ± 0.329
0.493ValHis: 0.493 ± 0.752
2.957ValIle: 2.957 ± 1.449
1.479ValLys: 1.479 ± 0.554
6.407ValLeu: 6.407 ± 1.202
0.986ValMet: 0.986 ± 0.62
1.479ValAsn: 1.479 ± 0.329
1.479ValPro: 1.479 ± 0.329
3.45ValGln: 3.45 ± 0.6
0.493ValArg: 0.493 ± 0.47
9.857ValSer: 9.857 ± 3.135
3.45ValThr: 3.45 ± 1.045
1.479ValVal: 1.479 ± 0.671
1.971ValTrp: 1.971 ± 0.365
0.986ValTyr: 0.986 ± 0.62
0.0ValXaa: 0.0 ± 0.0
Trp
1.971TrpAla: 1.971 ± 1.35
0.0TrpCys: 0.0 ± 0.0
0.986TrpAsp: 0.986 ± 0.376
0.493TrpGlu: 0.493 ± 0.47
0.0TrpPhe: 0.0 ± 0.0
0.986TrpGly: 0.986 ± 0.376
0.493TrpHis: 0.493 ± 0.47
0.493TrpIle: 0.493 ± 0.349
0.986TrpLys: 0.986 ± 0.474
2.464TrpLeu: 2.464 ± 1.225
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.986TrpPro: 0.986 ± 0.699
1.971TrpGln: 1.971 ± 0.591
1.971TrpArg: 1.971 ± 0.846
0.493TrpSer: 0.493 ± 0.493
3.45TrpThr: 3.45 ± 0.409
1.479TrpVal: 1.479 ± 0.554
0.0TrpTrp: 0.0 ± 0.0
0.986TrpTyr: 0.986 ± 0.376
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.971TyrAla: 1.971 ± 0.365
0.986TyrCys: 0.986 ± 0.474
0.493TyrAsp: 0.493 ± 0.47
0.493TyrGlu: 0.493 ± 0.349
0.986TyrPhe: 0.986 ± 0.699
0.493TyrGly: 0.493 ± 0.349
0.986TyrHis: 0.986 ± 0.94
0.0TyrIle: 0.0 ± 0.0
0.986TyrLys: 0.986 ± 0.699
4.436TyrLeu: 4.436 ± 1.325
0.493TyrMet: 0.493 ± 0.349
0.986TyrAsn: 0.986 ± 0.474
1.479TyrPro: 1.479 ± 0.924
0.986TyrGln: 0.986 ± 0.573
0.493TyrArg: 0.493 ± 0.493
4.436TyrSer: 4.436 ± 1.745
1.479TyrThr: 1.479 ± 0.776
0.493TyrVal: 0.493 ± 0.349
0.0TyrTrp: 0.0 ± 0.0
1.479TyrTyr: 1.479 ± 0.554
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2030 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski