Amino acid dipepetide frequency for Nocardia stercoris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
24.021AlaAla: 24.021 ± 0.175
0.971AlaCys: 0.971 ± 0.028
9.29AlaAsp: 9.29 ± 0.084
8.442AlaGlu: 8.442 ± 0.079
3.293AlaPhe: 3.293 ± 0.048
13.584AlaGly: 13.584 ± 0.119
2.856AlaHis: 2.856 ± 0.044
4.616AlaIle: 4.616 ± 0.057
2.416AlaLys: 2.416 ± 0.051
13.648AlaLeu: 13.648 ± 0.102
2.598AlaMet: 2.598 ± 0.039
2.361AlaAsn: 2.361 ± 0.034
6.867AlaPro: 6.867 ± 0.075
4.202AlaGln: 4.202 ± 0.051
9.437AlaArg: 9.437 ± 0.094
4.952AlaSer: 4.952 ± 0.056
8.358AlaThr: 8.358 ± 0.076
12.787AlaVal: 12.787 ± 0.108
1.691AlaTrp: 1.691 ± 0.027
2.439AlaTyr: 2.439 ± 0.043
0.0AlaXaa: 0.0 ± 0.0
Cys
1.082CysAla: 1.082 ± 0.028
0.102CysCys: 0.102 ± 0.01
0.476CysAsp: 0.476 ± 0.017
0.355CysGlu: 0.355 ± 0.014
0.222CysPhe: 0.222 ± 0.009
0.926CysGly: 0.926 ± 0.025
0.171CysHis: 0.171 ± 0.008
0.213CysIle: 0.213 ± 0.01
0.107CysLys: 0.107 ± 0.007
0.664CysLeu: 0.664 ± 0.022
0.117CysMet: 0.117 ± 0.007
0.137CysAsn: 0.137 ± 0.008
0.477CysPro: 0.477 ± 0.017
0.159CysGln: 0.159 ± 0.009
0.575CysArg: 0.575 ± 0.018
0.464CysSer: 0.464 ± 0.017
0.483CysThr: 0.483 ± 0.017
0.609CysVal: 0.609 ± 0.018
0.12CysTrp: 0.12 ± 0.008
0.181CysTyr: 0.181 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
7.563AspAla: 7.563 ± 0.081
0.441AspCys: 0.441 ± 0.018
3.587AspAsp: 3.587 ± 0.046
3.431AspGlu: 3.431 ± 0.04
1.721AspPhe: 1.721 ± 0.032
5.634AspGly: 5.634 ± 0.066
1.533AspHis: 1.533 ± 0.028
2.399AspIle: 2.399 ± 0.031
1.031AspLys: 1.031 ± 0.027
6.693AspLeu: 6.693 ± 0.073
0.853AspMet: 0.853 ± 0.02
1.162AspAsn: 1.162 ± 0.027
5.008AspPro: 5.008 ± 0.06
1.728AspGln: 1.728 ± 0.033
5.566AspArg: 5.566 ± 0.064
3.019AspSer: 3.019 ± 0.046
3.522AspThr: 3.522 ± 0.036
4.528AspVal: 4.528 ± 0.048
0.999AspTrp: 0.999 ± 0.022
1.382AspTyr: 1.382 ± 0.026
0.0AspXaa: 0.0 ± 0.0
Glu
5.503GluAla: 5.503 ± 0.057
0.329GluCys: 0.329 ± 0.012
1.981GluAsp: 1.981 ± 0.034
2.031GluGlu: 2.031 ± 0.036
1.986GluPhe: 1.986 ± 0.033
2.799GluGly: 2.799 ± 0.046
1.535GluHis: 1.535 ± 0.025
2.65GluIle: 2.65 ± 0.039
0.941GluLys: 0.941 ± 0.024
7.226GluLeu: 7.226 ± 0.085
0.879GluMet: 0.879 ± 0.023
0.985GluAsn: 0.985 ± 0.023
3.271GluPro: 3.271 ± 0.043
2.292GluGln: 2.292 ± 0.035
4.529GluArg: 4.529 ± 0.061
2.821GluSer: 2.821 ± 0.04
2.674GluThr: 2.674 ± 0.035
4.227GluVal: 4.227 ± 0.05
0.745GluTrp: 0.745 ± 0.018
1.171GluTyr: 1.171 ± 0.024
0.0GluXaa: 0.0 ± 0.0
Phe
4.195PheAla: 4.195 ± 0.048
0.25PheCys: 0.25 ± 0.011
2.512PheAsp: 2.512 ± 0.051
1.556PheGlu: 1.556 ± 0.036
0.831PhePhe: 0.831 ± 0.02
3.466PheGly: 3.466 ± 0.042
0.625PheHis: 0.625 ± 0.02
0.742PheIle: 0.742 ± 0.019
0.396PheLys: 0.396 ± 0.017
2.421PheLeu: 2.421 ± 0.04
0.407PheMet: 0.407 ± 0.014
0.504PheAsn: 0.504 ± 0.017
1.429PhePro: 1.429 ± 0.032
0.7PheGln: 0.7 ± 0.021
1.874PheArg: 1.874 ± 0.031
1.451PheSer: 1.451 ± 0.024
2.06PheThr: 2.06 ± 0.035
2.533PheVal: 2.533 ± 0.038
0.387PheTrp: 0.387 ± 0.014
0.591PheTyr: 0.591 ± 0.016
0.0PheXaa: 0.0 ± 0.0
Gly
10.867GlyAla: 10.867 ± 0.097
0.838GlyCys: 0.838 ± 0.023
4.966GlyAsp: 4.966 ± 0.046
4.258GlyGlu: 4.258 ± 0.046
3.029GlyPhe: 3.029 ± 0.041
7.944GlyGly: 7.944 ± 0.091
2.188GlyHis: 2.188 ± 0.032
4.078GlyIle: 4.078 ± 0.056
2.09GlyLys: 2.09 ± 0.037
8.867GlyLeu: 8.867 ± 0.08
1.994GlyMet: 1.994 ± 0.031
1.916GlyAsn: 1.916 ± 0.039
5.106GlyPro: 5.106 ± 0.062
2.548GlyGln: 2.548 ± 0.043
6.845GlyArg: 6.845 ± 0.062
5.452GlySer: 5.452 ± 0.062
6.257GlyThr: 6.257 ± 0.074
7.439GlyVal: 7.439 ± 0.086
1.551GlyTrp: 1.551 ± 0.032
2.495GlyTyr: 2.495 ± 0.038
0.0GlyXaa: 0.0 ± 0.0
His
2.624HisAla: 2.624 ± 0.038
0.218HisCys: 0.218 ± 0.01
1.383HisAsp: 1.383 ± 0.026
1.092HisGlu: 1.092 ± 0.026
0.653HisPhe: 0.653 ± 0.018
2.24HisGly: 2.24 ± 0.036
0.708HisHis: 0.708 ± 0.025
0.768HisIle: 0.768 ± 0.018
0.314HisLys: 0.314 ± 0.013
2.193HisLeu: 2.193 ± 0.036
0.356HisMet: 0.356 ± 0.013
0.484HisAsn: 0.484 ± 0.016
1.846HisPro: 1.846 ± 0.027
0.612HisGln: 0.612 ± 0.016
2.107HisArg: 2.107 ± 0.034
1.145HisSer: 1.145 ± 0.025
1.403HisThr: 1.403 ± 0.024
1.507HisVal: 1.507 ± 0.028
0.34HisTrp: 0.34 ± 0.014
0.527HisTyr: 0.527 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
5.954IleAla: 5.954 ± 0.064
0.308IleCys: 0.308 ± 0.011
3.142IleAsp: 3.142 ± 0.041
2.426IleGlu: 2.426 ± 0.035
0.875IlePhe: 0.875 ± 0.023
4.311IleGly: 4.311 ± 0.055
0.733IleHis: 0.733 ± 0.019
1.042IleIle: 1.042 ± 0.027
0.614IleLys: 0.614 ± 0.022
3.024IleLeu: 3.024 ± 0.042
0.565IleMet: 0.565 ± 0.016
0.81IleAsn: 0.81 ± 0.021
2.256IlePro: 2.256 ± 0.039
0.846IleGln: 0.846 ± 0.018
2.714IleArg: 2.714 ± 0.039
2.042IleSer: 2.042 ± 0.03
2.61IleThr: 2.61 ± 0.039
3.428IleVal: 3.428 ± 0.043
0.413IleTrp: 0.413 ± 0.015
0.708IleTyr: 0.708 ± 0.018
0.0IleXaa: 0.0 ± 0.0
Lys
2.155LysAla: 2.155 ± 0.042
0.098LysCys: 0.098 ± 0.008
0.847LysAsp: 0.847 ± 0.025
0.693LysGlu: 0.693 ± 0.025
0.517LysPhe: 0.517 ± 0.017
1.238LysGly: 1.238 ± 0.031
0.388LysHis: 0.388 ± 0.017
0.849LysIle: 0.849 ± 0.021
0.484LysLys: 0.484 ± 0.02
1.847LysLeu: 1.847 ± 0.035
0.374LysMet: 0.374 ± 0.015
0.42LysAsn: 0.42 ± 0.018
1.151LysPro: 1.151 ± 0.03
0.647LysGln: 0.647 ± 0.02
1.146LysArg: 1.146 ± 0.027
1.057LysSer: 1.057 ± 0.026
1.103LysThr: 1.103 ± 0.024
1.564LysVal: 1.564 ± 0.036
0.235LysTrp: 0.235 ± 0.012
0.434LysTyr: 0.434 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
15.101LeuAla: 15.101 ± 0.1
0.817LeuCys: 0.817 ± 0.019
6.993LeuAsp: 6.993 ± 0.085
4.496LeuGlu: 4.496 ± 0.049
2.737LeuPhe: 2.737 ± 0.042
8.958LeuGly: 8.958 ± 0.076
2.194LeuHis: 2.194 ± 0.039
3.831LeuIle: 3.831 ± 0.043
1.301LeuLys: 1.301 ± 0.028
10.382LeuLeu: 10.382 ± 0.092
1.511LeuMet: 1.511 ± 0.026
1.841LeuAsn: 1.841 ± 0.033
6.488LeuPro: 6.488 ± 0.075
2.337LeuGln: 2.337 ± 0.036
8.379LeuArg: 8.379 ± 0.075
5.491LeuSer: 5.491 ± 0.054
6.937LeuThr: 6.937 ± 0.059
8.615LeuVal: 8.615 ± 0.081
1.223LeuTrp: 1.223 ± 0.027
1.685LeuTyr: 1.685 ± 0.033
0.0LeuXaa: 0.0 ± 0.0
Met
2.203MetAla: 2.203 ± 0.038
0.142MetCys: 0.142 ± 0.008
0.829MetAsp: 0.829 ± 0.022
0.579MetGlu: 0.579 ± 0.018
0.606MetPhe: 0.606 ± 0.016
1.273MetGly: 1.273 ± 0.032
0.378MetHis: 0.378 ± 0.013
0.818MetIle: 0.818 ± 0.02
0.361MetLys: 0.361 ± 0.014
1.94MetLeu: 1.94 ± 0.032
0.352MetMet: 0.352 ± 0.014
0.493MetAsn: 0.493 ± 0.016
1.142MetPro: 1.142 ± 0.025
0.502MetGln: 0.502 ± 0.015
1.458MetArg: 1.458 ± 0.029
1.397MetSer: 1.397 ± 0.027
1.593MetThr: 1.593 ± 0.032
1.476MetVal: 1.476 ± 0.026
0.242MetTrp: 0.242 ± 0.014
0.325MetTyr: 0.325 ± 0.013
0.0MetXaa: 0.0 ± 0.0
Asn
2.309AsnAla: 2.309 ± 0.036
0.172AsnCys: 0.172 ± 0.011
0.963AsnAsp: 0.963 ± 0.022
0.778AsnGlu: 0.778 ± 0.02
0.567AsnPhe: 0.567 ± 0.017
1.967AsnGly: 1.967 ± 0.04
0.425AsnHis: 0.425 ± 0.015
0.804AsnIle: 0.804 ± 0.022
0.383AsnLys: 0.383 ± 0.013
1.919AsnLeu: 1.919 ± 0.034
0.376AsnMet: 0.376 ± 0.014
0.477AsnAsn: 0.477 ± 0.018
1.602AsnPro: 1.602 ± 0.029
0.605AsnGln: 0.605 ± 0.02
1.504AsnArg: 1.504 ± 0.025
1.188AsnSer: 1.188 ± 0.03
1.259AsnThr: 1.259 ± 0.028
1.421AsnVal: 1.421 ± 0.03
0.349AsnTrp: 0.349 ± 0.013
0.497AsnTyr: 0.497 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
9.213ProAla: 9.213 ± 0.095
0.294ProCys: 0.294 ± 0.013
4.693ProAsp: 4.693 ± 0.051
3.915ProGlu: 3.915 ± 0.047
1.518ProPhe: 1.518 ± 0.03
6.493ProGly: 6.493 ± 0.073
1.249ProHis: 1.249 ± 0.023
2.225ProIle: 2.225 ± 0.035
1.079ProLys: 1.079 ± 0.025
5.142ProLeu: 5.142 ± 0.07
1.103ProMet: 1.103 ± 0.025
1.222ProAsn: 1.222 ± 0.03
3.346ProPro: 3.346 ± 0.071
1.903ProGln: 1.903 ± 0.039
3.583ProArg: 3.583 ± 0.044
2.855ProSer: 2.855 ± 0.038
3.484ProThr: 3.484 ± 0.044
5.686ProVal: 5.686 ± 0.08
0.861ProTrp: 0.861 ± 0.021
1.096ProTyr: 1.096 ± 0.025
0.0ProXaa: 0.0 ± 0.0
Gln
3.681GlnAla: 3.681 ± 0.044
0.2GlnCys: 0.2 ± 0.01
1.227GlnAsp: 1.227 ± 0.025
1.071GlnGlu: 1.071 ± 0.025
0.873GlnPhe: 0.873 ± 0.019
1.911GlnGly: 1.911 ± 0.039
0.678GlnHis: 0.678 ± 0.018
1.3GlnIle: 1.3 ± 0.028
0.46GlnLys: 0.46 ± 0.017
3.601GlnLeu: 3.601 ± 0.048
0.538GlnMet: 0.538 ± 0.02
0.547GlnAsn: 0.547 ± 0.016
1.942GlnPro: 1.942 ± 0.036
1.426GlnGln: 1.426 ± 0.034
2.708GlnArg: 2.708 ± 0.042
1.326GlnSer: 1.326 ± 0.027
1.331GlnThr: 1.331 ± 0.025
2.731GlnVal: 2.731 ± 0.038
0.549GlnTrp: 0.549 ± 0.017
0.665GlnTyr: 0.665 ± 0.019
0.0GlnXaa: 0.0 ± 0.0
Arg
9.583ArgAla: 9.583 ± 0.083
0.539ArgCys: 0.539 ± 0.016
4.229ArgAsp: 4.229 ± 0.05
3.899ArgGlu: 3.899 ± 0.046
2.51ArgPhe: 2.51 ± 0.036
5.208ArgGly: 5.208 ± 0.049
1.908ArgHis: 1.908 ± 0.036
3.829ArgIle: 3.829 ± 0.047
1.451ArgLys: 1.451 ± 0.032
7.99ArgLeu: 7.99 ± 0.077
1.836ArgMet: 1.836 ± 0.031
1.574ArgAsn: 1.574 ± 0.03
4.493ArgPro: 4.493 ± 0.059
2.189ArgGln: 2.189 ± 0.035
6.811ArgArg: 6.811 ± 0.088
4.115ArgSer: 4.115 ± 0.044
5.075ArgThr: 5.075 ± 0.045
5.804ArgVal: 5.804 ± 0.062
1.376ArgTrp: 1.376 ± 0.028
1.879ArgTyr: 1.879 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
7.054SerAla: 7.054 ± 0.06
0.413SerCys: 0.413 ± 0.014
3.045SerAsp: 3.045 ± 0.04
2.253SerGlu: 2.253 ± 0.035
1.6SerPhe: 1.6 ± 0.031
6.072SerGly: 6.072 ± 0.061
0.956SerHis: 0.956 ± 0.023
2.009SerIle: 2.009 ± 0.029
0.932SerLys: 0.932 ± 0.026
4.449SerLeu: 4.449 ± 0.048
1.231SerMet: 1.231 ± 0.023
1.007SerAsn: 1.007 ± 0.026
2.922SerPro: 2.922 ± 0.035
1.252SerGln: 1.252 ± 0.026
3.444SerArg: 3.444 ± 0.046
2.785SerSer: 2.785 ± 0.052
3.389SerThr: 3.389 ± 0.049
4.363SerVal: 4.363 ± 0.055
0.899SerTrp: 0.899 ± 0.022
1.167SerTyr: 1.167 ± 0.024
0.0SerXaa: 0.0 ± 0.0
Thr
9.434ThrAla: 9.434 ± 0.077
0.437ThrCys: 0.437 ± 0.016
4.112ThrAsp: 4.112 ± 0.051
3.416ThrGlu: 3.416 ± 0.046
1.734ThrPhe: 1.734 ± 0.031
6.927ThrGly: 6.927 ± 0.076
1.24ThrHis: 1.24 ± 0.023
2.25ThrIle: 2.25 ± 0.033
0.987ThrLys: 0.987 ± 0.027
5.769ThrLeu: 5.769 ± 0.061
1.105ThrMet: 1.105 ± 0.025
1.046ThrAsn: 1.046 ± 0.027
4.073ThrPro: 4.073 ± 0.051
1.435ThrGln: 1.435 ± 0.026
3.867ThrArg: 3.867 ± 0.042
3.09ThrSer: 3.09 ± 0.043
4.447ThrThr: 4.447 ± 0.075
6.82ThrVal: 6.82 ± 0.071
0.84ThrTrp: 0.84 ± 0.023
1.281ThrTyr: 1.281 ± 0.026
0.0ThrXaa: 0.0 ± 0.0
Val
12.275ValAla: 12.275 ± 0.117
0.726ValCys: 0.726 ± 0.018
5.507ValAsp: 5.507 ± 0.055
4.29ValGlu: 4.29 ± 0.049
2.456ValPhe: 2.456 ± 0.036
6.78ValGly: 6.78 ± 0.059
1.908ValHis: 1.908 ± 0.034
3.162ValIle: 3.162 ± 0.05
1.307ValLys: 1.307 ± 0.029
9.522ValLeu: 9.522 ± 0.091
1.339ValMet: 1.339 ± 0.027
1.718ValAsn: 1.718 ± 0.027
5.452ValPro: 5.452 ± 0.077
2.117ValGln: 2.117 ± 0.034
6.515ValArg: 6.515 ± 0.062
4.509ValSer: 4.509 ± 0.055
6.071ValThr: 6.071 ± 0.065
8.682ValVal: 8.682 ± 0.095
1.059ValTrp: 1.059 ± 0.026
1.5ValTyr: 1.5 ± 0.028
0.0ValXaa: 0.0 ± 0.0
Trp
1.586TrpAla: 1.586 ± 0.031
0.129TrpCys: 0.129 ± 0.008
0.715TrpAsp: 0.715 ± 0.023
0.629TrpGlu: 0.629 ± 0.017
0.537TrpPhe: 0.537 ± 0.02
0.956TrpGly: 0.956 ± 0.023
0.382TrpHis: 0.382 ± 0.014
0.636TrpIle: 0.636 ± 0.017
0.297TrpLys: 0.297 ± 0.013
1.678TrpLeu: 1.678 ± 0.032
0.321TrpMet: 0.321 ± 0.011
0.429TrpAsn: 0.429 ± 0.019
0.772TrpPro: 0.772 ± 0.02
0.617TrpGln: 0.617 ± 0.017
1.22TrpArg: 1.22 ± 0.025
1.0TrpSer: 1.0 ± 0.024
0.974TrpThr: 0.974 ± 0.023
1.064TrpVal: 1.064 ± 0.024
0.337TrpTrp: 0.337 ± 0.014
0.334TrpTyr: 0.334 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.425TyrAla: 2.425 ± 0.038
0.221TyrCys: 0.221 ± 0.012
1.301TyrAsp: 1.301 ± 0.027
0.966TyrGlu: 0.966 ± 0.023
0.664TyrPhe: 0.664 ± 0.02
2.042TyrGly: 2.042 ± 0.036
0.462TyrHis: 0.462 ± 0.014
0.597TyrIle: 0.597 ± 0.019
0.295TyrLys: 0.295 ± 0.012
2.343TyrLeu: 2.343 ± 0.038
0.256TyrMet: 0.256 ± 0.012
0.43TyrAsn: 0.43 ± 0.016
1.315TyrPro: 1.315 ± 0.03
0.65TyrGln: 0.65 ± 0.017
2.016TyrArg: 2.016 ± 0.034
1.081TyrSer: 1.081 ± 0.025
1.284TyrThr: 1.284 ± 0.024
1.611TyrVal: 1.611 ± 0.038
0.399TyrTrp: 0.399 ± 0.013
0.467TyrTyr: 0.467 ± 0.018
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.001XaaXaa: 0.001 ± 0.001
Statistics based on 6448 proteins (2145449 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski