Amino acid dipepetide frequency for Riemerella anatipestifer RA-CH-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.567AlaAla: 3.567 ± 0.088	0.527AlaCys: 0.527 ± 0.029	3.264AlaAsp: 3.264 ± 0.077	4.555AlaGlu: 4.555 ± 0.108	3.203AlaPhe: 3.203 ± 0.068	3.774AlaGly: 3.774 ± 0.093	1.117AlaHis: 1.117 ± 0.044	4.635AlaIle: 4.635 ± 0.09	5.164AlaLys: 5.164 ± 0.104	6.129AlaLeu: 6.129 ± 0.126	1.599AlaMet: 1.599 ± 0.056	3.403AlaAsn: 3.403 ± 0.071	1.848AlaPro: 1.848 ± 0.057	2.626AlaGln: 2.626 ± 0.07	2.127AlaArg: 2.127 ± 0.062	4.038AlaSer: 4.038 ± 0.089	3.384AlaThr: 3.384 ± 0.073	3.803AlaVal: 3.803 ± 0.083	0.564AlaTrp: 0.564 ± 0.034	2.505AlaTyr: 2.505 ± 0.067	0.0AlaXaa: 0.0 ± 0.0
Cys	0.425CysAla: 0.425 ± 0.026	0.096CysCys: 0.096 ± 0.012	0.352CysAsp: 0.352 ± 0.022	0.438CysGlu: 0.438 ± 0.028	0.417CysPhe: 0.417 ± 0.027	0.621CysGly: 0.621 ± 0.034	0.168CysHis: 0.168 ± 0.016	0.552CysIle: 0.552 ± 0.027	0.44CysLys: 0.44 ± 0.027	0.67CysLeu: 0.67 ± 0.038	0.13CysMet: 0.13 ± 0.014	0.392CysAsn: 0.392 ± 0.023	0.315CysPro: 0.315 ± 0.025	0.211CysGln: 0.211 ± 0.02	0.243CysArg: 0.243 ± 0.02	0.487CysSer: 0.487 ± 0.027	0.363CysThr: 0.363 ± 0.025	0.441CysVal: 0.441 ± 0.024	0.064CysTrp: 0.064 ± 0.009	0.283CysTyr: 0.283 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	3.32AspAla: 3.32 ± 0.071	0.357AspCys: 0.357 ± 0.023	2.377AspAsp: 2.377 ± 0.064	3.832AspGlu: 3.832 ± 0.072	3.761AspPhe: 3.761 ± 0.076	3.21AspGly: 3.21 ± 0.078	0.641AspHis: 0.641 ± 0.03	4.21AspIle: 4.21 ± 0.089	4.546AspLys: 4.546 ± 0.1	5.06AspLeu: 5.06 ± 0.091	1.068AspMet: 1.068 ± 0.036	2.941AspAsn: 2.941 ± 0.071	1.344AspPro: 1.344 ± 0.045	1.157AspGln: 1.157 ± 0.039	1.867AspArg: 1.867 ± 0.058	2.652AspSer: 2.652 ± 0.066	2.641AspThr: 2.641 ± 0.065	2.993AspVal: 2.993 ± 0.068	0.752AspTrp: 0.752 ± 0.039	2.843AspTyr: 2.843 ± 0.065	0.0AspXaa: 0.0 ± 0.0
Glu	4.781GluAla: 4.781 ± 0.11	0.361GluCys: 0.361 ± 0.024	3.486GluAsp: 3.486 ± 0.074	5.911GluGlu: 5.911 ± 0.136	3.009GluPhe: 3.009 ± 0.074	3.94GluGly: 3.94 ± 0.083	1.175GluHis: 1.175 ± 0.04	5.994GluIle: 5.994 ± 0.099	6.901GluLys: 6.901 ± 0.14	6.253GluLeu: 6.253 ± 0.105	1.694GluMet: 1.694 ± 0.048	4.679GluAsn: 4.679 ± 0.095	1.628GluPro: 1.628 ± 0.061	2.778GluGln: 2.778 ± 0.074	2.769GluArg: 2.769 ± 0.07	3.084GluSer: 3.084 ± 0.06	3.639GluThr: 3.639 ± 0.073	5.164GluVal: 5.164 ± 0.091	0.74GluTrp: 0.74 ± 0.033	2.683GluTyr: 2.683 ± 0.061	0.0GluXaa: 0.0 ± 0.0
Phe	2.82PheAla: 2.82 ± 0.073	0.453PheCys: 0.453 ± 0.03	2.814PheAsp: 2.814 ± 0.064	3.097PheGlu: 3.097 ± 0.066	2.788PhePhe: 2.788 ± 0.067	3.687PheGly: 3.687 ± 0.08	0.801PheHis: 0.801 ± 0.029	4.016PheIle: 4.016 ± 0.091	3.608PheLys: 3.608 ± 0.08	4.88PheLeu: 4.88 ± 0.101	1.165PheMet: 1.165 ± 0.035	3.296PheAsn: 3.296 ± 0.066	1.809PhePro: 1.809 ± 0.05	1.665PheGln: 1.665 ± 0.044	2.0PheArg: 2.0 ± 0.058	4.319PheSer: 4.319 ± 0.09	2.635PheThr: 2.635 ± 0.059	3.17PheVal: 3.17 ± 0.072	0.66PheTrp: 0.66 ± 0.033	2.379PheTyr: 2.379 ± 0.065	0.0PheXaa: 0.0 ± 0.0
Gly	4.279GlyAla: 4.279 ± 0.081	0.489GlyCys: 0.489 ± 0.029	2.993GlyAsp: 2.993 ± 0.073	3.738GlyGlu: 3.738 ± 0.086	3.478GlyPhe: 3.478 ± 0.083	4.549GlyGly: 4.549 ± 0.091	1.027GlyHis: 1.027 ± 0.039	5.241GlyIle: 5.241 ± 0.102	5.519GlyLys: 5.519 ± 0.089	5.685GlyLeu: 5.685 ± 0.097	1.532GlyMet: 1.532 ± 0.046	3.628GlyAsn: 3.628 ± 0.093	0.99GlyPro: 0.99 ± 0.039	1.882GlyGln: 1.882 ± 0.054	2.303GlyArg: 2.303 ± 0.069	3.738GlySer: 3.738 ± 0.078	3.583GlyThr: 3.583 ± 0.087	4.663GlyVal: 4.663 ± 0.076	0.712GlyTrp: 0.712 ± 0.043	2.944GlyTyr: 2.944 ± 0.072	0.0GlyXaa: 0.0 ± 0.0
His	0.787HisAla: 0.787 ± 0.038	0.166HisCys: 0.166 ± 0.015	0.655HisAsp: 0.655 ± 0.032	0.749HisGlu: 0.749 ± 0.038	1.171HisPhe: 1.171 ± 0.046	0.907HisGly: 0.907 ± 0.039	0.539HisHis: 0.539 ± 0.032	1.48HisIle: 1.48 ± 0.048	1.242HisLys: 1.242 ± 0.044	1.956HisLeu: 1.956 ± 0.059	0.259HisMet: 0.259 ± 0.019	1.021HisAsn: 1.021 ± 0.036	0.715HisPro: 0.715 ± 0.035	0.891HisGln: 0.891 ± 0.043	0.689HisArg: 0.689 ± 0.038	1.091HisSer: 1.091 ± 0.04	0.989HisThr: 0.989 ± 0.048	0.44HisVal: 0.44 ± 0.021	0.211HisTrp: 0.211 ± 0.018	0.905HisTyr: 0.905 ± 0.038	0.0HisXaa: 0.0 ± 0.0
Ile	5.003IleAla: 5.003 ± 0.086	0.629IleCys: 0.629 ± 0.03	4.502IleAsp: 4.502 ± 0.082	5.394IleGlu: 5.394 ± 0.101	3.748IlePhe: 3.748 ± 0.077	4.702IleGly: 4.702 ± 0.087	1.17IleHis: 1.17 ± 0.042	5.886IleIle: 5.886 ± 0.118	6.568IleLys: 6.568 ± 0.111	7.207IleLeu: 7.207 ± 0.118	1.427IleMet: 1.427 ± 0.048	4.543IleAsn: 4.543 ± 0.089	3.14IlePro: 3.14 ± 0.061	2.501IleGln: 2.501 ± 0.065	2.495IleArg: 2.495 ± 0.061	5.874IleSer: 5.874 ± 0.101	4.284IleThr: 4.284 ± 0.084	4.212IleVal: 4.212 ± 0.093	0.638IleTrp: 0.638 ± 0.033	2.836IleTyr: 2.836 ± 0.066	0.0IleXaa: 0.0 ± 0.0
Lys	5.416LysAla: 5.416 ± 0.105	0.405LysCys: 0.405 ± 0.027	4.785LysAsp: 4.785 ± 0.079	7.094LysGlu: 7.094 ± 0.119	3.376LysPhe: 3.376 ± 0.07	4.779LysGly: 4.779 ± 0.08	1.368LysHis: 1.368 ± 0.05	7.079LysIle: 7.079 ± 0.112	7.659LysLys: 7.659 ± 0.142	6.88LysLeu: 6.88 ± 0.114	2.416LysMet: 2.416 ± 0.064	6.083LysAsn: 6.083 ± 0.102	2.543LysPro: 2.543 ± 0.063	2.983LysGln: 2.983 ± 0.071	2.88LysArg: 2.88 ± 0.076	4.714LysSer: 4.714 ± 0.091	5.069LysThr: 5.069 ± 0.082	5.417LysVal: 5.417 ± 0.092	0.813LysTrp: 0.813 ± 0.032	3.47LysTyr: 3.47 ± 0.074	0.0LysXaa: 0.0 ± 0.0
Leu	5.805LeuAla: 5.805 ± 0.099	0.705LeuCys: 0.705 ± 0.036	5.235LeuAsp: 5.235 ± 0.091	6.865LeuGlu: 6.865 ± 0.111	4.647LeuPhe: 4.647 ± 0.101	6.52LeuGly: 6.52 ± 0.125	1.449LeuHis: 1.449 ± 0.047	6.042LeuIle: 6.042 ± 0.111	8.33LeuLys: 8.33 ± 0.118	8.469LeuLeu: 8.469 ± 0.146	2.272LeuMet: 2.272 ± 0.056	5.818LeuAsn: 5.818 ± 0.105	3.69LeuPro: 3.69 ± 0.086	3.097LeuGln: 3.097 ± 0.078	3.238LeuArg: 3.238 ± 0.069	7.279LeuSer: 7.279 ± 0.109	4.565LeuThr: 4.565 ± 0.078	5.685LeuVal: 5.685 ± 0.117	0.811LeuTrp: 0.811 ± 0.032	3.318LeuTyr: 3.318 ± 0.077	0.0LeuXaa: 0.0 ± 0.0
Met	1.612MetAla: 1.612 ± 0.051	0.131MetCys: 0.131 ± 0.015	1.034MetAsp: 1.034 ± 0.039	1.497MetGlu: 1.497 ± 0.052	0.942MetPhe: 0.942 ± 0.041	1.534MetGly: 1.534 ± 0.051	0.323MetHis: 0.323 ± 0.018	1.579MetIle: 1.579 ± 0.05	2.549MetLys: 2.549 ± 0.06	2.096MetLeu: 2.096 ± 0.06	0.731MetMet: 0.731 ± 0.03	1.291MetAsn: 1.291 ± 0.044	0.867MetPro: 0.867 ± 0.033	0.776MetGln: 0.776 ± 0.034	0.864MetArg: 0.864 ± 0.04	1.496MetSer: 1.496 ± 0.046	1.098MetThr: 1.098 ± 0.039	1.464MetVal: 1.464 ± 0.045	0.176MetTrp: 0.176 ± 0.018	0.637MetTyr: 0.637 ± 0.032	0.0MetXaa: 0.0 ± 0.0
Asn	3.797AsnAla: 3.797 ± 0.072	0.369AsnCys: 0.369 ± 0.029	2.778AsnAsp: 2.778 ± 0.064	3.716AsnGlu: 3.716 ± 0.069	3.267AsnPhe: 3.267 ± 0.075	3.877AsnGly: 3.877 ± 0.094	1.183AsnHis: 1.183 ± 0.041	5.311AsnIle: 5.311 ± 0.094	4.68AsnLys: 4.68 ± 0.082	5.978AsnLeu: 5.978 ± 0.095	1.139AsnMet: 1.139 ± 0.04	3.653AsnAsn: 3.653 ± 0.099	2.944AsnPro: 2.944 ± 0.064	2.584AsnGln: 2.584 ± 0.07	2.195AsnArg: 2.195 ± 0.063	3.524AsnSer: 3.524 ± 0.083	3.591AsnThr: 3.591 ± 0.082	3.119AsnVal: 3.119 ± 0.069	0.711AsnTrp: 0.711 ± 0.035	2.987AsnTyr: 2.987 ± 0.076	0.0AsnXaa: 0.0 ± 0.0
Pro	1.76ProAla: 1.76 ± 0.055	0.235ProCys: 0.235 ± 0.019	1.773ProAsp: 1.773 ± 0.053	2.642ProGlu: 2.642 ± 0.065	1.764ProPhe: 1.764 ± 0.053	1.47ProGly: 1.47 ± 0.048	0.635ProHis: 0.635 ± 0.026	2.577ProIle: 2.577 ± 0.062	3.126ProLys: 3.126 ± 0.071	2.977ProLeu: 2.977 ± 0.072	0.72ProMet: 0.72 ± 0.035	2.421ProAsn: 2.421 ± 0.06	0.801ProPro: 0.801 ± 0.043	1.342ProGln: 1.342 ± 0.04	1.027ProArg: 1.027 ± 0.043	2.37ProSer: 2.37 ± 0.068	1.924ProThr: 1.924 ± 0.051	2.057ProVal: 2.057 ± 0.054	0.316ProTrp: 0.316 ± 0.02	1.612ProTyr: 1.612 ± 0.049	0.0ProXaa: 0.0 ± 0.0
Gln	1.996GlnAla: 1.996 ± 0.061	0.185GlnCys: 0.185 ± 0.017	1.607GlnAsp: 1.607 ± 0.048	2.733GlnGlu: 2.733 ± 0.06	1.592GlnPhe: 1.592 ± 0.048	1.965GlnGly: 1.965 ± 0.054	0.549GlnHis: 0.549 ± 0.026	2.772GlnIle: 2.772 ± 0.064	3.634GlnLys: 3.634 ± 0.085	3.384GlnLeu: 3.384 ± 0.083	0.916GlnMet: 0.916 ± 0.036	2.594GlnAsn: 2.594 ± 0.071	1.225GlnPro: 1.225 ± 0.044	1.543GlnGln: 1.543 ± 0.046	1.454GlnArg: 1.454 ± 0.052	2.199GlnSer: 2.199 ± 0.054	1.883GlnThr: 1.883 ± 0.058	2.007GlnVal: 2.007 ± 0.05	0.449GlnTrp: 0.449 ± 0.028	1.461GlnTyr: 1.461 ± 0.053	0.0GlnXaa: 0.0 ± 0.0
Arg	2.084ArgAla: 2.084 ± 0.057	0.229ArgCys: 0.229 ± 0.02	1.636ArgAsp: 1.636 ± 0.048	2.606ArgGlu: 2.606 ± 0.071	1.936ArgPhe: 1.936 ± 0.049	2.026ArgGly: 2.026 ± 0.058	0.594ArgHis: 0.594 ± 0.03	2.702ArgIle: 2.702 ± 0.066	3.1ArgLys: 3.1 ± 0.07	3.538ArgLeu: 3.538 ± 0.073	0.969ArgMet: 0.969 ± 0.038	2.341ArgAsn: 2.341 ± 0.065	1.117ArgPro: 1.117 ± 0.045	1.213ArgGln: 1.213 ± 0.049	1.535ArgArg: 1.535 ± 0.05	1.749ArgSer: 1.749 ± 0.059	1.866ArgThr: 1.866 ± 0.048	2.331ArgVal: 2.331 ± 0.06	0.393ArgTrp: 0.393 ± 0.023	1.543ArgTyr: 1.543 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	3.828SerAla: 3.828 ± 0.077	0.567SerCys: 0.567 ± 0.035	3.247SerAsp: 3.247 ± 0.07	4.453SerGlu: 4.453 ± 0.087	3.898SerPhe: 3.898 ± 0.076	4.425SerGly: 4.425 ± 0.09	1.031SerHis: 1.031 ± 0.044	4.95SerIle: 4.95 ± 0.094	5.086SerLys: 5.086 ± 0.083	6.179SerLeu: 6.179 ± 0.109	1.267SerMet: 1.267 ± 0.042	3.564SerAsn: 3.564 ± 0.088	2.083SerPro: 2.083 ± 0.057	2.312SerGln: 2.312 ± 0.065	2.073SerArg: 2.073 ± 0.057	4.303SerSer: 4.303 ± 0.112	3.238SerThr: 3.238 ± 0.073	4.252SerVal: 4.252 ± 0.079	0.645SerTrp: 0.645 ± 0.031	2.763SerTyr: 2.763 ± 0.077	0.0SerXaa: 0.0 ± 0.0
Thr	3.349ThrAla: 3.349 ± 0.074	0.332ThrCys: 0.332 ± 0.022	2.993ThrAsp: 2.993 ± 0.068	3.843ThrGlu: 3.843 ± 0.08	2.601ThrPhe: 2.601 ± 0.057	3.481ThrGly: 3.481 ± 0.074	1.021ThrHis: 1.021 ± 0.052	3.777ThrIle: 3.777 ± 0.08	4.1ThrLys: 4.1 ± 0.074	5.369ThrLeu: 5.369 ± 0.088	0.926ThrMet: 0.926 ± 0.04	3.082ThrAsn: 3.082 ± 0.078	2.667ThrPro: 2.667 ± 0.063	2.214ThrGln: 2.214 ± 0.062	1.548ThrArg: 1.548 ± 0.047	3.521ThrSer: 3.521 ± 0.078	3.047ThrThr: 3.047 ± 0.081	3.05ThrVal: 3.05 ± 0.073	0.433ThrTrp: 0.433 ± 0.024	2.227ThrTyr: 2.227 ± 0.062	0.0ThrXaa: 0.0 ± 0.0
Val	3.994ValAla: 3.994 ± 0.086	0.468ValCys: 0.468 ± 0.028	3.178ValAsp: 3.178 ± 0.079	4.242ValGlu: 4.242 ± 0.079	3.255ValPhe: 3.255 ± 0.074	4.138ValGly: 4.138 ± 0.071	0.871ValHis: 0.871 ± 0.033	4.345ValIle: 4.345 ± 0.09	4.945ValLys: 4.945 ± 0.087	5.995ValLeu: 5.995 ± 0.1	1.512ValMet: 1.512 ± 0.048	3.419ValAsn: 3.419 ± 0.066	2.125ValPro: 2.125 ± 0.061	1.859ValGln: 1.859 ± 0.054	2.1ValArg: 2.1 ± 0.057	4.368ValSer: 4.368 ± 0.079	2.897ValThr: 2.897 ± 0.073	4.434ValVal: 4.434 ± 0.092	0.58ValTrp: 0.58 ± 0.025	2.623ValTyr: 2.623 ± 0.07	0.0ValXaa: 0.0 ± 0.0
Trp	0.664TrpAla: 0.664 ± 0.028	0.079TrpCys: 0.079 ± 0.012	0.556TrpAsp: 0.556 ± 0.028	0.706TrpGlu: 0.706 ± 0.035	0.562TrpPhe: 0.562 ± 0.029	0.666TrpGly: 0.666 ± 0.039	0.218TrpHis: 0.218 ± 0.017	0.708TrpIle: 0.708 ± 0.033	0.82TrpLys: 0.82 ± 0.036	1.049TrpLeu: 1.049 ± 0.039	0.236TrpMet: 0.236 ± 0.02	0.685TrpAsn: 0.685 ± 0.033	0.119TrpPro: 0.119 ± 0.015	0.459TrpGln: 0.459 ± 0.029	0.403TrpArg: 0.403 ± 0.024	0.575TrpSer: 0.575 ± 0.034	0.482TrpThr: 0.482 ± 0.025	0.749TrpVal: 0.749 ± 0.035	0.137TrpTrp: 0.137 ± 0.013	0.399TrpTyr: 0.399 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.546TyrAla: 2.546 ± 0.069	0.325TyrCys: 0.325 ± 0.022	2.306TyrAsp: 2.306 ± 0.064	2.559TyrGlu: 2.559 ± 0.068	2.645TyrPhe: 2.645 ± 0.071	2.703TyrGly: 2.703 ± 0.063	0.983TyrHis: 0.983 ± 0.041	2.907TyrIle: 2.907 ± 0.06	3.209TyrLys: 3.209 ± 0.071	4.084TyrLeu: 4.084 ± 0.086	0.717TyrMet: 0.717 ± 0.031	2.549TyrAsn: 2.549 ± 0.07	1.575TyrPro: 1.575 ± 0.045	2.055TyrGln: 2.055 ± 0.065	1.697TyrArg: 1.697 ± 0.06	2.784TyrSer: 2.784 ± 0.069	2.405TyrThr: 2.405 ± 0.066	1.899TyrVal: 1.899 ± 0.053	0.469TyrTrp: 0.469 ± 0.029	2.009TyrTyr: 2.009 ± 0.071	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2187 proteins (686533 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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