Amino acid dipepetide frequency for Beihai picorna-like virus 64

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.265AlaAla: 6.265 ± 3.57
0.783AlaCys: 0.783 ± 0.455
3.524AlaAsp: 3.524 ± 0.355
5.09AlaGlu: 5.09 ± 0.647
3.132AlaPhe: 3.132 ± 0.583
4.307AlaGly: 4.307 ± 1.703
0.783AlaHis: 0.783 ± 0.146
3.524AlaIle: 3.524 ± 0.355
2.741AlaLys: 2.741 ± 0.811
5.873AlaLeu: 5.873 ± 0.191
0.783AlaMet: 0.783 ± 0.146
3.132AlaAsn: 3.132 ± 2.386
1.175AlaPro: 1.175 ± 0.683
3.915AlaGln: 3.915 ± 0.474
1.958AlaArg: 1.958 ± 0.665
5.09AlaSer: 5.09 ± 1.248
6.656AlaThr: 6.656 ± 3.343
3.132AlaVal: 3.132 ± 0.583
1.175AlaTrp: 1.175 ± 0.519
2.349AlaTyr: 2.349 ± 0.437
0.0AlaXaa: 0.0 ± 0.0
Cys
0.392CysAla: 0.392 ± 0.228
0.0CysCys: 0.0 ± 0.0
1.566CysAsp: 1.566 ± 0.911
0.783CysGlu: 0.783 ± 0.455
0.783CysPhe: 0.783 ± 0.146
0.783CysGly: 0.783 ± 0.455
0.0CysHis: 0.0 ± 0.0
0.392CysIle: 0.392 ± 0.228
1.175CysLys: 1.175 ± 0.519
1.566CysLeu: 1.566 ± 0.31
1.566CysMet: 1.566 ± 0.291
0.783CysAsn: 0.783 ± 0.455
1.175CysPro: 1.175 ± 0.082
0.783CysGln: 0.783 ± 0.455
1.175CysArg: 1.175 ± 0.683
0.0CysSer: 0.0 ± 0.0
1.175CysThr: 1.175 ± 0.082
1.175CysVal: 1.175 ± 0.683
0.0CysTrp: 0.0 ± 0.0
0.392CysTyr: 0.392 ± 0.228
0.0CysXaa: 0.0 ± 0.0
Asp
3.132AspAla: 3.132 ± 1.785
1.566AspCys: 1.566 ± 0.31
3.132AspAsp: 3.132 ± 0.018
5.09AspGlu: 5.09 ± 0.556
4.307AspPhe: 4.307 ± 0.1
1.566AspGly: 1.566 ± 0.291
1.175AspHis: 1.175 ± 0.082
5.482AspIle: 5.482 ± 0.182
1.958AspLys: 1.958 ± 0.538
7.831AspLeu: 7.831 ± 0.856
1.175AspMet: 1.175 ± 0.519
2.741AspAsn: 2.741 ± 0.993
3.132AspPro: 3.132 ± 0.583
1.566AspGln: 1.566 ± 0.291
2.741AspArg: 2.741 ± 0.209
2.349AspSer: 2.349 ± 0.164
3.915AspThr: 3.915 ± 1.676
7.439AspVal: 7.439 ± 0.119
1.958AspTrp: 1.958 ± 0.064
2.349AspTyr: 2.349 ± 1.038
0.0AspXaa: 0.0 ± 0.0
Glu
2.349GluAla: 2.349 ± 1.038
0.0GluCys: 0.0 ± 0.0
3.524GluAsp: 3.524 ± 0.355
1.566GluGlu: 1.566 ± 0.31
4.699GluPhe: 4.699 ± 0.929
3.524GluGly: 3.524 ± 0.246
0.783GluHis: 0.783 ± 0.455
3.524GluIle: 3.524 ± 0.355
0.783GluLys: 0.783 ± 0.146
3.524GluLeu: 3.524 ± 0.956
2.741GluMet: 2.741 ± 0.209
2.349GluAsn: 2.349 ± 0.437
3.524GluPro: 3.524 ± 0.355
1.175GluGln: 1.175 ± 0.683
2.349GluArg: 2.349 ± 0.765
5.482GluSer: 5.482 ± 1.986
4.307GluThr: 4.307 ± 0.501
2.741GluVal: 2.741 ± 0.392
0.0GluTrp: 0.0 ± 0.0
1.958GluTyr: 1.958 ± 0.064
0.0GluXaa: 0.0 ± 0.0
Phe
4.699PheAla: 4.699 ± 0.874
1.175PheCys: 1.175 ± 0.683
2.349PheAsp: 2.349 ± 0.765
1.566PheGlu: 1.566 ± 0.893
3.132PhePhe: 3.132 ± 0.62
2.741PheGly: 2.741 ± 0.811
1.566PheHis: 1.566 ± 0.31
1.566PheIle: 1.566 ± 0.31
3.524PheLys: 3.524 ± 0.847
5.09PheLeu: 5.09 ± 0.556
1.175PheMet: 1.175 ± 0.683
3.524PheAsn: 3.524 ± 0.355
1.566PhePro: 1.566 ± 0.31
1.566PheGln: 1.566 ± 0.291
2.741PheArg: 2.741 ± 0.811
7.439PheSer: 7.439 ± 0.72
4.699PheThr: 4.699 ± 0.328
4.699PheVal: 4.699 ± 0.328
0.0PheTrp: 0.0 ± 0.0
3.132PheTyr: 3.132 ± 0.62
0.0PheXaa: 0.0 ± 0.0
Gly
2.741GlyAla: 2.741 ± 1.412
0.392GlyCys: 0.392 ± 0.228
5.482GlyAsp: 5.482 ± 0.182
3.915GlyGlu: 3.915 ± 1.931
2.349GlyPhe: 2.349 ± 0.164
4.307GlyGly: 4.307 ± 2.304
0.783GlyHis: 0.783 ± 0.146
3.915GlyIle: 3.915 ± 0.127
4.307GlyLys: 4.307 ± 0.702
4.307GlyLeu: 4.307 ± 0.702
1.175GlyMet: 1.175 ± 0.519
2.349GlyAsn: 2.349 ± 1.038
2.349GlyPro: 2.349 ± 1.038
1.175GlyGln: 1.175 ± 0.519
0.392GlyArg: 0.392 ± 0.228
3.915GlySer: 3.915 ± 1.075
3.524GlyThr: 3.524 ± 2.159
3.915GlyVal: 3.915 ± 1.075
0.392GlyTrp: 0.392 ± 0.228
2.741GlyTyr: 2.741 ± 0.392
0.0GlyXaa: 0.0 ± 0.0
His
0.392HisAla: 0.392 ± 0.228
0.0HisCys: 0.0 ± 0.0
0.392HisAsp: 0.392 ± 0.373
0.783HisGlu: 0.783 ± 0.455
1.566HisPhe: 1.566 ± 0.31
0.783HisGly: 0.783 ± 0.455
0.783HisHis: 0.783 ± 0.146
1.175HisIle: 1.175 ± 0.519
0.783HisLys: 0.783 ± 0.146
0.392HisLeu: 0.392 ± 0.228
0.0HisMet: 0.0 ± 0.0
0.392HisAsn: 0.392 ± 0.228
0.392HisPro: 0.392 ± 0.228
0.783HisGln: 0.783 ± 0.455
1.175HisArg: 1.175 ± 0.082
1.566HisSer: 1.566 ± 0.911
1.566HisThr: 1.566 ± 0.291
1.958HisVal: 1.958 ± 0.538
0.392HisTrp: 0.392 ± 0.228
1.175HisTyr: 1.175 ± 0.683
0.0HisXaa: 0.0 ± 0.0
Ile
6.265IleAla: 6.265 ± 1.767
0.392IleCys: 0.392 ± 0.228
1.566IleAsp: 1.566 ± 0.31
1.566IleGlu: 1.566 ± 0.31
2.349IlePhe: 2.349 ± 0.164
3.524IleGly: 3.524 ± 0.355
1.958IleHis: 1.958 ± 1.139
4.307IleIle: 4.307 ± 0.1
2.741IleLys: 2.741 ± 0.209
3.915IleLeu: 3.915 ± 0.474
1.175IleMet: 1.175 ± 0.082
1.566IleAsn: 1.566 ± 0.31
2.741IlePro: 2.741 ± 2.013
0.783IleGln: 0.783 ± 0.146
0.783IleArg: 0.783 ± 0.747
5.09IleSer: 5.09 ± 0.556
3.915IleThr: 3.915 ± 1.33
3.132IleVal: 3.132 ± 1.221
0.783IleTrp: 0.783 ± 0.146
2.741IleTyr: 2.741 ± 0.392
0.0IleXaa: 0.0 ± 0.0
Lys
2.349LysAla: 2.349 ± 0.164
0.392LysCys: 0.392 ± 0.228
3.524LysAsp: 3.524 ± 0.246
3.132LysGlu: 3.132 ± 1.822
1.566LysPhe: 1.566 ± 0.291
3.524LysGly: 3.524 ± 0.847
0.783LysHis: 0.783 ± 0.455
4.699LysIle: 4.699 ± 0.328
3.524LysLys: 3.524 ± 2.05
5.09LysLeu: 5.09 ± 0.045
0.0LysMet: 0.0 ± 0.0
3.915LysAsn: 3.915 ± 0.127
1.566LysPro: 1.566 ± 0.31
1.958LysGln: 1.958 ± 0.064
3.915LysArg: 3.915 ± 0.127
6.265LysSer: 6.265 ± 1.84
2.349LysThr: 2.349 ± 1.366
1.958LysVal: 1.958 ± 0.064
0.783LysTrp: 0.783 ± 0.146
0.783LysTyr: 0.783 ± 0.455
0.0LysXaa: 0.0 ± 0.0
Leu
5.09LeuAla: 5.09 ± 0.045
1.958LeuCys: 1.958 ± 1.139
5.873LeuAsp: 5.873 ± 0.191
3.524LeuGlu: 3.524 ± 1.449
5.482LeuPhe: 5.482 ± 0.784
4.307LeuGly: 4.307 ± 1.102
1.175LeuHis: 1.175 ± 0.082
2.741LeuIle: 2.741 ± 0.209
5.873LeuLys: 5.873 ± 2.214
7.048LeuLeu: 7.048 ± 2.897
1.958LeuMet: 1.958 ± 0.064
5.09LeuAsn: 5.09 ± 1.157
4.307LeuPro: 4.307 ± 1.303
3.915LeuGln: 3.915 ± 1.075
7.048LeuArg: 7.048 ± 0.492
7.831LeuSer: 7.831 ± 2.15
3.132LeuThr: 3.132 ± 1.184
7.439LeuVal: 7.439 ± 0.119
1.175LeuTrp: 1.175 ± 1.12
3.132LeuTyr: 3.132 ± 0.62
0.0LeuXaa: 0.0 ± 0.0
Met
2.349MetAla: 2.349 ± 0.437
0.783MetCys: 0.783 ± 0.455
0.392MetAsp: 0.392 ± 0.373
3.132MetGlu: 3.132 ± 1.221
1.566MetPhe: 1.566 ± 0.911
0.392MetGly: 0.392 ± 0.373
0.783MetHis: 0.783 ± 0.146
0.0MetIle: 0.0 ± 0.0
2.741MetLys: 2.741 ± 0.392
1.175MetLeu: 1.175 ± 0.082
0.783MetMet: 0.783 ± 0.747
0.783MetAsn: 0.783 ± 0.146
1.958MetPro: 1.958 ± 0.538
1.175MetGln: 1.175 ± 0.082
2.741MetArg: 2.741 ± 0.811
1.958MetSer: 1.958 ± 0.538
0.783MetThr: 0.783 ± 0.146
1.566MetVal: 1.566 ± 0.291
0.0MetTrp: 0.0 ± 0.0
0.783MetTyr: 0.783 ± 0.146
0.0MetXaa: 0.0 ± 0.0
Asn
2.349AsnAla: 2.349 ± 0.164
0.392AsnCys: 0.392 ± 0.228
3.132AsnAsp: 3.132 ± 2.386
1.175AsnGlu: 1.175 ± 1.12
2.741AsnPhe: 2.741 ± 0.209
3.524AsnGly: 3.524 ± 0.355
0.783AsnHis: 0.783 ± 0.455
2.741AsnIle: 2.741 ± 0.209
1.175AsnLys: 1.175 ± 0.082
3.915AsnLeu: 3.915 ± 0.474
1.566AsnMet: 1.566 ± 0.911
5.873AsnAsn: 5.873 ± 2.596
2.741AsnPro: 2.741 ± 1.412
1.175AsnGln: 1.175 ± 0.519
1.566AsnArg: 1.566 ± 0.911
6.656AsnSer: 6.656 ± 1.467
1.175AsnThr: 1.175 ± 1.12
3.915AsnVal: 3.915 ± 0.127
0.783AsnTrp: 0.783 ± 0.747
1.566AsnTyr: 1.566 ± 0.31
0.0AsnXaa: 0.0 ± 0.0
Pro
1.958ProAla: 1.958 ± 0.538
0.392ProCys: 0.392 ± 0.373
3.132ProAsp: 3.132 ± 0.62
1.566ProGlu: 1.566 ± 0.291
5.09ProPhe: 5.09 ± 0.647
1.175ProGly: 1.175 ± 0.683
0.783ProHis: 0.783 ± 0.455
3.132ProIle: 3.132 ± 0.583
1.958ProLys: 1.958 ± 0.064
2.741ProLeu: 2.741 ± 0.993
2.349ProMet: 2.349 ± 0.285
1.958ProAsn: 1.958 ± 0.064
1.566ProPro: 1.566 ± 0.291
1.566ProGln: 1.566 ± 0.31
1.566ProArg: 1.566 ± 0.291
3.132ProSer: 3.132 ± 0.018
2.741ProThr: 2.741 ± 0.811
3.524ProVal: 3.524 ± 0.355
1.175ProTrp: 1.175 ± 0.082
2.741ProTyr: 2.741 ± 0.209
0.0ProXaa: 0.0 ± 0.0
Gln
2.349GlnAla: 2.349 ± 0.437
0.783GlnCys: 0.783 ± 0.455
1.175GlnAsp: 1.175 ± 0.519
2.741GlnGlu: 2.741 ± 1.412
1.566GlnPhe: 1.566 ± 0.291
2.741GlnGly: 2.741 ± 0.993
0.392GlnHis: 0.392 ± 0.373
1.175GlnIle: 1.175 ± 0.519
0.392GlnLys: 0.392 ± 0.228
4.307GlnLeu: 4.307 ± 0.702
0.392GlnMet: 0.392 ± 0.228
2.741GlnAsn: 2.741 ± 0.209
2.741GlnPro: 2.741 ± 0.209
2.349GlnGln: 2.349 ± 1.038
1.566GlnArg: 1.566 ± 0.291
3.915GlnSer: 3.915 ± 1.075
1.566GlnThr: 1.566 ± 0.893
2.349GlnVal: 2.349 ± 1.366
0.392GlnTrp: 0.392 ± 0.373
1.566GlnTyr: 1.566 ± 0.31
0.0GlnXaa: 0.0 ± 0.0
Arg
2.349ArgAla: 2.349 ± 0.437
0.783ArgCys: 0.783 ± 0.455
2.349ArgAsp: 2.349 ± 0.765
3.915ArgGlu: 3.915 ± 1.075
1.958ArgPhe: 1.958 ± 1.266
4.699ArgGly: 4.699 ± 0.273
0.0ArgHis: 0.0 ± 0.0
1.175ArgIle: 1.175 ± 0.082
3.132ArgLys: 3.132 ± 0.62
4.699ArgLeu: 4.699 ± 0.929
0.783ArgMet: 0.783 ± 0.455
0.783ArgAsn: 0.783 ± 0.455
3.915ArgPro: 3.915 ± 0.729
1.958ArgGln: 1.958 ± 0.538
3.132ArgArg: 3.132 ± 0.583
4.307ArgSer: 4.307 ± 1.703
4.307ArgThr: 4.307 ± 1.102
2.349ArgVal: 2.349 ± 0.765
0.392ArgTrp: 0.392 ± 0.228
1.566ArgTyr: 1.566 ± 0.893
0.0ArgXaa: 0.0 ± 0.0
Ser
5.873SerAla: 5.873 ± 1.995
2.349SerCys: 2.349 ± 0.164
6.656SerAsp: 6.656 ± 1.467
2.349SerGlu: 2.349 ± 0.164
7.048SerPhe: 7.048 ± 1.695
3.132SerGly: 3.132 ± 0.018
2.349SerHis: 2.349 ± 0.765
4.307SerIle: 4.307 ± 0.1
5.09SerLys: 5.09 ± 0.556
11.355SerLeu: 11.355 ± 2.396
2.741SerMet: 2.741 ± 0.209
4.307SerAsn: 4.307 ± 1.102
2.349SerPro: 2.349 ± 1.366
2.741SerGln: 2.741 ± 0.392
5.873SerArg: 5.873 ± 1.011
6.265SerSer: 6.265 ± 0.037
3.915SerThr: 3.915 ± 2.277
6.265SerVal: 6.265 ± 1.239
0.783SerTrp: 0.783 ± 0.747
4.307SerTyr: 4.307 ± 2.304
0.0SerXaa: 0.0 ± 0.0
Thr
5.482ThrAla: 5.482 ± 2.222
0.783ThrCys: 0.783 ± 0.747
6.265ThrAsp: 6.265 ± 1.767
2.349ThrGlu: 2.349 ± 0.765
3.524ThrPhe: 3.524 ± 0.246
3.524ThrGly: 3.524 ± 2.159
0.783ThrHis: 0.783 ± 0.146
2.741ThrIle: 2.741 ± 0.811
1.566ThrLys: 1.566 ± 0.911
4.699ThrLeu: 4.699 ± 0.929
1.566ThrMet: 1.566 ± 0.31
1.566ThrAsn: 1.566 ± 0.291
2.349ThrPro: 2.349 ± 1.038
1.958ThrGln: 1.958 ± 0.064
2.349ThrArg: 2.349 ± 0.765
5.482ThrSer: 5.482 ± 0.182
3.132ThrThr: 3.132 ± 1.785
5.09ThrVal: 5.09 ± 0.556
1.175ThrTrp: 1.175 ± 0.519
3.132ThrTyr: 3.132 ± 1.785
0.0ThrXaa: 0.0 ± 0.0
Val
5.873ValAla: 5.873 ± 0.792
1.566ValCys: 1.566 ± 0.911
5.873ValAsp: 5.873 ± 0.191
3.132ValGlu: 3.132 ± 0.583
1.566ValPhe: 1.566 ± 0.911
2.741ValGly: 2.741 ± 0.392
0.392ValHis: 0.392 ± 0.228
3.132ValIle: 3.132 ± 0.018
5.482ValLys: 5.482 ± 1.986
5.482ValLeu: 5.482 ± 1.986
3.132ValMet: 3.132 ± 0.746
1.958ValAsn: 1.958 ± 0.064
3.132ValPro: 3.132 ± 1.221
3.132ValGln: 3.132 ± 1.184
1.958ValArg: 1.958 ± 0.538
9.789ValSer: 9.789 ± 2.122
3.132ValThr: 3.132 ± 0.62
6.656ValVal: 6.656 ± 0.337
0.392ValTrp: 0.392 ± 0.228
4.699ValTyr: 4.699 ± 0.929
0.0ValXaa: 0.0 ± 0.0
Trp
0.783TrpAla: 0.783 ± 0.146
0.392TrpCys: 0.392 ± 0.373
0.783TrpAsp: 0.783 ± 0.146
0.392TrpGlu: 0.392 ± 0.373
0.783TrpPhe: 0.783 ± 0.146
0.392TrpGly: 0.392 ± 0.373
0.0TrpHis: 0.0 ± 0.0
0.783TrpIle: 0.783 ± 0.455
0.783TrpLys: 0.783 ± 0.455
1.175TrpLeu: 1.175 ± 0.082
0.0TrpMet: 0.0 ± 0.0
0.392TrpAsn: 0.392 ± 0.373
0.783TrpPro: 0.783 ± 0.455
1.175TrpGln: 1.175 ± 0.519
1.175TrpArg: 1.175 ± 1.12
1.566TrpSer: 1.566 ± 0.291
0.392TrpThr: 0.392 ± 0.373
0.783TrpVal: 0.783 ± 0.146
0.0TrpTrp: 0.0 ± 0.0
0.783TrpTyr: 0.783 ± 0.146
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.349TyrAla: 2.349 ± 0.437
0.783TyrCys: 0.783 ± 0.146
3.915TyrAsp: 3.915 ± 0.474
3.132TyrGlu: 3.132 ± 0.018
2.741TyrPhe: 2.741 ± 0.209
2.741TyrGly: 2.741 ± 0.209
0.392TyrHis: 0.392 ± 0.228
0.783TyrIle: 0.783 ± 0.455
2.349TyrLys: 2.349 ± 0.437
3.915TyrLeu: 3.915 ± 0.127
0.392TyrMet: 0.392 ± 0.228
2.741TyrAsn: 2.741 ± 0.209
0.783TyrPro: 0.783 ± 0.455
2.349TyrGln: 2.349 ± 1.038
2.349TyrArg: 2.349 ± 0.437
1.958TyrSer: 1.958 ± 0.064
3.132TyrThr: 3.132 ± 0.018
3.524TyrVal: 3.524 ± 0.956
1.566TyrTrp: 1.566 ± 0.31
0.392TyrTyr: 0.392 ± 0.228
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2555 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski