Amino acid dipepetide frequency for Tobacco mosaic virus (strain OM) (TMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.811AlaAla: 6.811 ± 0.0
1.238AlaCys: 1.238 ± 0.0
2.477AlaAsp: 2.477 ± 0.0
1.858AlaGlu: 1.858 ± 0.0
3.096AlaPhe: 3.096 ± 0.0
4.334AlaGly: 4.334 ± 0.0
1.238AlaHis: 1.238 ± 0.0
1.858AlaIle: 1.858 ± 0.0
5.573AlaLys: 5.573 ± 0.0
8.669AlaLeu: 8.669 ± 0.0
2.477AlaMet: 2.477 ± 0.0
2.477AlaAsn: 2.477 ± 0.0
2.477AlaPro: 2.477 ± 0.0
1.238AlaGln: 1.238 ± 0.0
2.477AlaArg: 2.477 ± 0.0
5.573AlaSer: 5.573 ± 0.0
2.477AlaThr: 2.477 ± 0.0
8.05AlaVal: 8.05 ± 0.0
1.238AlaTrp: 1.238 ± 0.0
3.096AlaTyr: 3.096 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.238CysAla: 1.238 ± 0.0
0.619CysCys: 0.619 ± 0.0
1.238CysAsp: 1.238 ± 0.0
1.858CysGlu: 1.858 ± 0.0
0.619CysPhe: 0.619 ± 0.0
1.858CysGly: 1.858 ± 0.0
1.238CysHis: 1.238 ± 0.0
1.858CysIle: 1.858 ± 0.0
1.238CysLys: 1.238 ± 0.0
1.238CysLeu: 1.238 ± 0.0
0.619CysMet: 0.619 ± 0.0
0.619CysAsn: 0.619 ± 0.0
0.619CysPro: 0.619 ± 0.0
1.858CysGln: 1.858 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.619CysSer: 0.619 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.619CysVal: 0.619 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.619CysTyr: 0.619 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.715AspAla: 3.715 ± 0.0
0.619AspCys: 0.619 ± 0.0
2.477AspAsp: 2.477 ± 0.0
4.334AspGlu: 4.334 ± 0.0
3.096AspPhe: 3.096 ± 0.0
1.858AspGly: 1.858 ± 0.0
0.619AspHis: 0.619 ± 0.0
5.573AspIle: 5.573 ± 0.0
4.954AspLys: 4.954 ± 0.0
4.954AspLeu: 4.954 ± 0.0
3.715AspMet: 3.715 ± 0.0
0.619AspAsn: 0.619 ± 0.0
1.858AspPro: 1.858 ± 0.0
1.858AspGln: 1.858 ± 0.0
2.477AspArg: 2.477 ± 0.0
8.669AspSer: 8.669 ± 0.0
3.715AspThr: 3.715 ± 0.0
7.43AspVal: 7.43 ± 0.0
1.238AspTrp: 1.238 ± 0.0
0.619AspTyr: 0.619 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.477GluAla: 2.477 ± 0.0
0.0GluCys: 0.0 ± 0.0
4.334GluAsp: 4.334 ± 0.0
3.715GluGlu: 3.715 ± 0.0
4.334GluPhe: 4.334 ± 0.0
2.477GluGly: 2.477 ± 0.0
1.238GluHis: 1.238 ± 0.0
4.954GluIle: 4.954 ± 0.0
3.096GluLys: 3.096 ± 0.0
4.334GluLeu: 4.334 ± 0.0
1.858GluMet: 1.858 ± 0.0
1.858GluAsn: 1.858 ± 0.0
1.238GluPro: 1.238 ± 0.0
3.096GluGln: 3.096 ± 0.0
2.477GluArg: 2.477 ± 0.0
4.954GluSer: 4.954 ± 0.0
3.715GluThr: 3.715 ± 0.0
6.192GluVal: 6.192 ± 0.0
0.619GluTrp: 0.619 ± 0.0
3.096GluTyr: 3.096 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.858PheAla: 1.858 ± 0.0
1.858PheCys: 1.858 ± 0.0
4.334PheAsp: 4.334 ± 0.0
1.858PheGlu: 1.858 ± 0.0
1.858PhePhe: 1.858 ± 0.0
3.715PheGly: 3.715 ± 0.0
2.477PheHis: 2.477 ± 0.0
2.477PheIle: 2.477 ± 0.0
2.477PheLys: 2.477 ± 0.0
3.715PheLeu: 3.715 ± 0.0
0.619PheMet: 0.619 ± 0.0
1.238PheAsn: 1.238 ± 0.0
3.715PhePro: 3.715 ± 0.0
1.858PheGln: 1.858 ± 0.0
1.238PheArg: 1.238 ± 0.0
5.573PheSer: 5.573 ± 0.0
1.858PheThr: 1.858 ± 0.0
3.715PheVal: 3.715 ± 0.0
0.0PheTrp: 0.0 ± 0.0
2.477PheTyr: 2.477 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.096GlyAla: 3.096 ± 0.0
2.477GlyCys: 2.477 ± 0.0
5.573GlyAsp: 5.573 ± 0.0
2.477GlyGlu: 2.477 ± 0.0
1.858GlyPhe: 1.858 ± 0.0
2.477GlyGly: 2.477 ± 0.0
0.619GlyHis: 0.619 ± 0.0
1.858GlyIle: 1.858 ± 0.0
3.096GlyLys: 3.096 ± 0.0
3.096GlyLeu: 3.096 ± 0.0
0.0GlyMet: 0.0 ± 0.0
3.096GlyAsn: 3.096 ± 0.0
1.238GlyPro: 1.238 ± 0.0
1.238GlyGln: 1.238 ± 0.0
1.858GlyArg: 1.858 ± 0.0
3.715GlySer: 3.715 ± 0.0
0.619GlyThr: 0.619 ± 0.0
3.715GlyVal: 3.715 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
1.238GlyTyr: 1.238 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.238HisAla: 1.238 ± 0.0
1.238HisCys: 1.238 ± 0.0
1.238HisAsp: 1.238 ± 0.0
1.238HisGlu: 1.238 ± 0.0
1.238HisPhe: 1.238 ± 0.0
0.619HisGly: 0.619 ± 0.0
0.619HisHis: 0.619 ± 0.0
1.238HisIle: 1.238 ± 0.0
1.238HisLys: 1.238 ± 0.0
1.238HisLeu: 1.238 ± 0.0
1.238HisMet: 1.238 ± 0.0
0.619HisAsn: 0.619 ± 0.0
0.619HisPro: 0.619 ± 0.0
0.619HisGln: 0.619 ± 0.0
0.619HisArg: 0.619 ± 0.0
3.096HisSer: 3.096 ± 0.0
3.096HisThr: 3.096 ± 0.0
3.096HisVal: 3.096 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.238HisTyr: 1.238 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.096IleAla: 3.096 ± 0.0
0.0IleCys: 0.0 ± 0.0
4.334IleAsp: 4.334 ± 0.0
2.477IleGlu: 2.477 ± 0.0
0.619IlePhe: 0.619 ± 0.0
1.858IleGly: 1.858 ± 0.0
0.619IleHis: 0.619 ± 0.0
4.334IleIle: 4.334 ± 0.0
4.954IleLys: 4.954 ± 0.0
4.334IleLeu: 4.334 ± 0.0
0.619IleMet: 0.619 ± 0.0
3.096IleAsn: 3.096 ± 0.0
2.477IlePro: 2.477 ± 0.0
0.619IleGln: 0.619 ± 0.0
4.954IleArg: 4.954 ± 0.0
5.573IleSer: 5.573 ± 0.0
0.619IleThr: 0.619 ± 0.0
3.715IleVal: 3.715 ± 0.0
1.238IleTrp: 1.238 ± 0.0
0.619IleTyr: 0.619 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.477LysAla: 2.477 ± 0.0
0.619LysCys: 0.619 ± 0.0
5.573LysAsp: 5.573 ± 0.0
4.334LysGlu: 4.334 ± 0.0
3.715LysPhe: 3.715 ± 0.0
3.715LysGly: 3.715 ± 0.0
0.619LysHis: 0.619 ± 0.0
2.477LysIle: 2.477 ± 0.0
3.096LysLys: 3.096 ± 0.0
6.192LysLeu: 6.192 ± 0.0
1.238LysMet: 1.238 ± 0.0
1.858LysAsn: 1.858 ± 0.0
2.477LysPro: 2.477 ± 0.0
3.715LysGln: 3.715 ± 0.0
3.096LysArg: 3.096 ± 0.0
5.573LysSer: 5.573 ± 0.0
6.811LysThr: 6.811 ± 0.0
4.334LysVal: 4.334 ± 0.0
0.619LysTrp: 0.619 ± 0.0
2.477LysTyr: 2.477 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.192LeuAla: 6.192 ± 0.0
1.238LeuCys: 1.238 ± 0.0
7.43LeuAsp: 7.43 ± 0.0
10.526LeuGlu: 10.526 ± 0.0
6.192LeuPhe: 6.192 ± 0.0
2.477LeuGly: 2.477 ± 0.0
2.477LeuHis: 2.477 ± 0.0
4.334LeuIle: 4.334 ± 0.0
4.334LeuLys: 4.334 ± 0.0
10.526LeuLeu: 10.526 ± 0.0
1.858LeuMet: 1.858 ± 0.0
4.334LeuAsn: 4.334 ± 0.0
1.858LeuPro: 1.858 ± 0.0
3.096LeuGln: 3.096 ± 0.0
4.334LeuArg: 4.334 ± 0.0
7.43LeuSer: 7.43 ± 0.0
6.192LeuThr: 6.192 ± 0.0
9.907LeuVal: 9.907 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
3.096LeuTyr: 3.096 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.477MetAla: 2.477 ± 0.0
1.238MetCys: 1.238 ± 0.0
1.238MetAsp: 1.238 ± 0.0
1.858MetGlu: 1.858 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.858MetIle: 1.858 ± 0.0
1.858MetLys: 1.858 ± 0.0
1.238MetLeu: 1.238 ± 0.0
1.858MetMet: 1.858 ± 0.0
1.238MetAsn: 1.238 ± 0.0
1.858MetPro: 1.858 ± 0.0
1.858MetGln: 1.858 ± 0.0
1.858MetArg: 1.858 ± 0.0
3.096MetSer: 3.096 ± 0.0
1.238MetThr: 1.238 ± 0.0
1.858MetVal: 1.858 ± 0.0
0.619MetTrp: 0.619 ± 0.0
1.238MetTyr: 1.238 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.334AsnAla: 4.334 ± 0.0
0.619AsnCys: 0.619 ± 0.0
0.619AsnAsp: 0.619 ± 0.0
1.858AsnGlu: 1.858 ± 0.0
6.192AsnPhe: 6.192 ± 0.0
1.238AsnGly: 1.238 ± 0.0
0.619AsnHis: 0.619 ± 0.0
0.619AsnIle: 0.619 ± 0.0
0.619AsnLys: 0.619 ± 0.0
4.334AsnLeu: 4.334 ± 0.0
0.0AsnMet: 0.0 ± 0.0
1.858AsnAsn: 1.858 ± 0.0
0.619AsnPro: 0.619 ± 0.0
0.0AsnGln: 0.0 ± 0.0
3.096AsnArg: 3.096 ± 0.0
2.477AsnSer: 2.477 ± 0.0
3.096AsnThr: 3.096 ± 0.0
3.715AsnVal: 3.715 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
1.238AsnTyr: 1.238 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.954ProAla: 4.954 ± 0.0
0.0ProCys: 0.0 ± 0.0
1.238ProAsp: 1.238 ± 0.0
2.477ProGlu: 2.477 ± 0.0
0.0ProPhe: 0.0 ± 0.0
2.477ProGly: 2.477 ± 0.0
1.238ProHis: 1.238 ± 0.0
1.238ProIle: 1.238 ± 0.0
3.715ProLys: 3.715 ± 0.0
3.715ProLeu: 3.715 ± 0.0
3.096ProMet: 3.096 ± 0.0
1.858ProAsn: 1.858 ± 0.0
0.619ProPro: 0.619 ± 0.0
0.0ProGln: 0.0 ± 0.0
0.619ProArg: 0.619 ± 0.0
1.238ProSer: 1.238 ± 0.0
1.858ProThr: 1.858 ± 0.0
0.619ProVal: 0.619 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.858ProTyr: 1.858 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.238GlnAla: 1.238 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.619GlnAsp: 0.619 ± 0.0
1.858GlnGlu: 1.858 ± 0.0
2.477GlnPhe: 2.477 ± 0.0
1.858GlnGly: 1.858 ± 0.0
1.238GlnHis: 1.238 ± 0.0
3.715GlnIle: 3.715 ± 0.0
2.477GlnLys: 2.477 ± 0.0
3.096GlnLeu: 3.096 ± 0.0
1.858GlnMet: 1.858 ± 0.0
1.238GlnAsn: 1.238 ± 0.0
1.238GlnPro: 1.238 ± 0.0
1.858GlnGln: 1.858 ± 0.0
0.619GlnArg: 0.619 ± 0.0
2.477GlnSer: 2.477 ± 0.0
3.715GlnThr: 3.715 ± 0.0
0.619GlnVal: 0.619 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.238GlnTyr: 1.238 ± 0.0
0.619GlnXaa: 0.619 ± 0.0
Arg
1.858ArgAla: 1.858 ± 0.0
1.238ArgCys: 1.238 ± 0.0
3.096ArgAsp: 3.096 ± 0.0
3.096ArgGlu: 3.096 ± 0.0
0.619ArgPhe: 0.619 ± 0.0
3.096ArgGly: 3.096 ± 0.0
1.858ArgHis: 1.858 ± 0.0
1.238ArgIle: 1.238 ± 0.0
6.811ArgLys: 6.811 ± 0.0
5.573ArgLeu: 5.573 ± 0.0
0.0ArgMet: 0.0 ± 0.0
1.858ArgAsn: 1.858 ± 0.0
1.238ArgPro: 1.238 ± 0.0
1.858ArgGln: 1.858 ± 0.0
6.192ArgArg: 6.192 ± 0.0
3.096ArgSer: 3.096 ± 0.0
3.096ArgThr: 3.096 ± 0.0
4.954ArgVal: 4.954 ± 0.0
0.619ArgTrp: 0.619 ± 0.0
1.858ArgTyr: 1.858 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.477SerAla: 2.477 ± 0.0
0.619SerCys: 0.619 ± 0.0
4.334SerAsp: 4.334 ± 0.0
6.192SerGlu: 6.192 ± 0.0
2.477SerPhe: 2.477 ± 0.0
3.715SerGly: 3.715 ± 0.0
1.858SerHis: 1.858 ± 0.0
4.334SerIle: 4.334 ± 0.0
6.192SerLys: 6.192 ± 0.0
16.099SerLeu: 16.099 ± 0.0
2.477SerMet: 2.477 ± 0.0
3.096SerAsn: 3.096 ± 0.0
0.619SerPro: 0.619 ± 0.0
1.858SerGln: 1.858 ± 0.0
7.43SerArg: 7.43 ± 0.0
6.811SerSer: 6.811 ± 0.0
2.477SerThr: 2.477 ± 0.0
6.811SerVal: 6.811 ± 0.0
0.0SerTrp: 0.0 ± 0.0
3.096SerTyr: 3.096 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
7.43ThrAla: 7.43 ± 0.0
3.096ThrCys: 3.096 ± 0.0
0.619ThrAsp: 0.619 ± 0.0
2.477ThrGlu: 2.477 ± 0.0
5.573ThrPhe: 5.573 ± 0.0
2.477ThrGly: 2.477 ± 0.0
1.238ThrHis: 1.238 ± 0.0
1.238ThrIle: 1.238 ± 0.0
1.858ThrLys: 1.858 ± 0.0
4.334ThrLeu: 4.334 ± 0.0
1.238ThrMet: 1.238 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
2.477ThrPro: 2.477 ± 0.0
3.715ThrGln: 3.715 ± 0.0
4.954ThrArg: 4.954 ± 0.0
3.096ThrSer: 3.096 ± 0.0
2.477ThrThr: 2.477 ± 0.0
4.954ThrVal: 4.954 ± 0.0
0.619ThrTrp: 0.619 ± 0.0
3.096ThrTyr: 3.096 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.288ValAla: 9.288 ± 0.0
1.858ValCys: 1.858 ± 0.0
8.05ValAsp: 8.05 ± 0.0
3.715ValGlu: 3.715 ± 0.0
1.858ValPhe: 1.858 ± 0.0
0.619ValGly: 0.619 ± 0.0
3.715ValHis: 3.715 ± 0.0
4.334ValIle: 4.334 ± 0.0
3.715ValLys: 3.715 ± 0.0
6.192ValLeu: 6.192 ± 0.0
2.477ValMet: 2.477 ± 0.0
4.334ValAsn: 4.334 ± 0.0
3.715ValPro: 3.715 ± 0.0
1.858ValGln: 1.858 ± 0.0
3.096ValArg: 3.096 ± 0.0
6.811ValSer: 6.811 ± 0.0
6.192ValThr: 6.192 ± 0.0
4.334ValVal: 4.334 ± 0.0
1.238ValTrp: 1.238 ± 0.0
4.954ValTyr: 4.954 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.238TrpAsp: 1.238 ± 0.0
0.619TrpGlu: 0.619 ± 0.0
1.238TrpPhe: 1.238 ± 0.0
0.619TrpGly: 0.619 ± 0.0
0.619TrpHis: 0.619 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.619TrpLys: 0.619 ± 0.0
1.238TrpLeu: 1.238 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.619TrpAsn: 0.619 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.238TrpArg: 1.238 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.619TrpTyr: 0.619 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.477TyrAla: 2.477 ± 0.0
0.619TyrCys: 0.619 ± 0.0
4.334TyrAsp: 4.334 ± 0.0
1.238TyrGlu: 1.238 ± 0.0
1.858TyrPhe: 1.858 ± 0.0
1.858TyrGly: 1.858 ± 0.0
1.238TyrHis: 1.238 ± 0.0
0.619TyrIle: 0.619 ± 0.0
3.096TyrLys: 3.096 ± 0.0
3.715TyrLeu: 3.715 ± 0.0
0.619TyrMet: 0.619 ± 0.0
1.238TyrAsn: 1.238 ± 0.0
1.858TyrPro: 1.858 ± 0.0
1.238TyrGln: 1.238 ± 0.0
0.619TyrArg: 0.619 ± 0.0
3.096TyrSer: 3.096 ± 0.0
3.715TyrThr: 3.715 ± 0.0
3.715TyrVal: 3.715 ± 0.0
0.619TyrTrp: 0.619 ± 0.0
2.477TyrTyr: 2.477 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.619XaaGln: 0.619 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (1616 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski