Amino acid dipepetide frequency for Faba bean necrotic stunt virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.561AlaAla: 1.561 ± 1.035
1.561AlaCys: 1.561 ± 1.03
1.561AlaAsp: 1.561 ± 0.85
3.123AlaGlu: 3.123 ± 1.374
2.342AlaPhe: 2.342 ± 1.329
3.903AlaGly: 3.903 ± 1.436
1.561AlaHis: 1.561 ± 0.957
2.342AlaIle: 2.342 ± 0.95
0.781AlaLys: 0.781 ± 0.659
2.342AlaLeu: 2.342 ± 1.056
1.561AlaMet: 1.561 ± 1.253
2.342AlaAsn: 2.342 ± 1.031
2.342AlaPro: 2.342 ± 1.062
0.0AlaGln: 0.0 ± 0.0
3.123AlaArg: 3.123 ± 1.424
3.903AlaSer: 3.903 ± 2.644
2.342AlaThr: 2.342 ± 1.031
2.342AlaVal: 2.342 ± 2.031
1.561AlaTrp: 1.561 ± 0.98
3.123AlaTyr: 3.123 ± 1.142
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.561CysCys: 1.561 ± 0.85
3.903CysAsp: 3.903 ± 2.046
0.0CysGlu: 0.0 ± 0.0
0.781CysPhe: 0.781 ± 0.659
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.342CysIle: 2.342 ± 1.271
3.903CysLys: 3.903 ± 2.167
0.781CysLeu: 0.781 ± 0.773
0.0CysMet: 0.0 ± 0.0
2.342CysAsn: 2.342 ± 1.632
0.0CysPro: 0.0 ± 0.0
0.781CysGln: 0.781 ± 0.677
4.684CysArg: 4.684 ± 1.893
2.342CysSer: 2.342 ± 1.004
3.123CysThr: 3.123 ± 1.46
0.781CysVal: 0.781 ± 0.837
0.781CysTrp: 0.781 ± 0.659
1.561CysTyr: 1.561 ± 1.021
0.0CysXaa: 0.0 ± 0.0
Asp
3.903AspAla: 3.903 ± 1.445
0.781AspCys: 0.781 ± 0.677
6.245AspAsp: 6.245 ± 1.282
3.903AspGlu: 3.903 ± 1.137
2.342AspPhe: 2.342 ± 1.009
4.684AspGly: 4.684 ± 0.927
1.561AspHis: 1.561 ± 0.782
3.903AspIle: 3.903 ± 0.906
2.342AspLys: 2.342 ± 1.353
5.464AspLeu: 5.464 ± 2.185
2.342AspMet: 2.342 ± 0.876
0.781AspAsn: 0.781 ± 0.773
0.781AspPro: 0.781 ± 0.773
0.0AspGln: 0.0 ± 0.0
2.342AspArg: 2.342 ± 0.975
4.684AspSer: 4.684 ± 2.082
0.0AspThr: 0.0 ± 0.0
5.464AspVal: 5.464 ± 1.638
0.781AspTrp: 0.781 ± 0.694
3.903AspTyr: 3.903 ± 1.337
0.0AspXaa: 0.0 ± 0.0
Glu
3.903GluAla: 3.903 ± 1.662
3.123GluCys: 3.123 ± 1.631
11.71GluAsp: 11.71 ± 4.814
8.587GluGlu: 8.587 ± 2.854
4.684GluPhe: 4.684 ± 1.689
4.684GluGly: 4.684 ± 1.292
1.561GluHis: 1.561 ± 0.976
3.123GluIle: 3.123 ± 1.259
2.342GluLys: 2.342 ± 0.95
6.245GluLeu: 6.245 ± 2.192
0.781GluMet: 0.781 ± 0.659
2.342GluAsn: 2.342 ± 1.317
0.0GluPro: 0.0 ± 0.0
3.123GluGln: 3.123 ± 1.316
3.903GluArg: 3.903 ± 1.611
7.026GluSer: 7.026 ± 1.853
0.781GluThr: 0.781 ± 0.836
3.123GluVal: 3.123 ± 1.929
0.0GluTrp: 0.0 ± 0.0
3.123GluTyr: 3.123 ± 1.386
0.0GluXaa: 0.0 ± 0.0
Phe
2.342PheAla: 2.342 ± 1.223
0.781PheCys: 0.781 ± 0.796
0.781PheAsp: 0.781 ± 0.659
3.903PheGlu: 3.903 ± 1.445
1.561PhePhe: 1.561 ± 1.101
0.781PheGly: 0.781 ± 0.659
0.0PheHis: 0.0 ± 0.0
4.684PheIle: 4.684 ± 1.538
0.781PheLys: 0.781 ± 0.677
3.123PheLeu: 3.123 ± 1.51
1.561PheMet: 1.561 ± 0.998
3.903PheAsn: 3.903 ± 1.532
1.561PhePro: 1.561 ± 0.85
1.561PheGln: 1.561 ± 0.782
2.342PheArg: 2.342 ± 1.039
2.342PheSer: 2.342 ± 0.84
2.342PheThr: 2.342 ± 1.329
2.342PheVal: 2.342 ± 1.064
0.781PheTrp: 0.781 ± 0.796
1.561PheTyr: 1.561 ± 0.85
0.0PheXaa: 0.0 ± 0.0
Gly
1.561GlyAla: 1.561 ± 0.824
0.781GlyCys: 0.781 ± 0.696
2.342GlyAsp: 2.342 ± 1.169
5.464GlyGlu: 5.464 ± 3.167
1.561GlyPhe: 1.561 ± 1.161
3.123GlyGly: 3.123 ± 1.7
0.0GlyHis: 0.0 ± 0.0
4.684GlyIle: 4.684 ± 2.063
5.464GlyLys: 5.464 ± 2.915
3.123GlyLeu: 3.123 ± 1.379
1.561GlyMet: 1.561 ± 1.317
5.464GlyAsn: 5.464 ± 1.444
2.342GlyPro: 2.342 ± 1.445
1.561GlyGln: 1.561 ± 1.388
2.342GlyArg: 2.342 ± 1.038
3.903GlySer: 3.903 ± 1.642
0.781GlyThr: 0.781 ± 0.659
3.123GlyVal: 3.123 ± 0.873
0.0GlyTrp: 0.0 ± 0.0
5.464GlyTyr: 5.464 ± 2.182
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.781HisAsp: 0.781 ± 0.796
1.561HisGlu: 1.561 ± 0.957
1.561HisPhe: 1.561 ± 1.317
0.781HisGly: 0.781 ± 0.796
0.0HisHis: 0.0 ± 0.0
2.342HisIle: 2.342 ± 1.346
0.0HisLys: 0.0 ± 0.0
3.903HisLeu: 3.903 ± 1.027
0.0HisMet: 0.0 ± 0.0
0.781HisAsn: 0.781 ± 0.694
0.0HisPro: 0.0 ± 0.0
3.123HisGln: 3.123 ± 0.984
0.781HisArg: 0.781 ± 0.677
0.781HisSer: 0.781 ± 0.694
1.561HisThr: 1.561 ± 1.061
0.781HisVal: 0.781 ± 0.694
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.903IleAla: 3.903 ± 1.909
3.123IleCys: 3.123 ± 1.462
0.781IleAsp: 0.781 ± 0.696
6.245IleGlu: 6.245 ± 2.806
1.561IlePhe: 1.561 ± 0.825
3.123IleGly: 3.123 ± 1.599
1.561IleHis: 1.561 ± 0.782
6.245IleIle: 6.245 ± 1.458
4.684IleLys: 4.684 ± 2.032
2.342IleLeu: 2.342 ± 1.233
2.342IleMet: 2.342 ± 1.861
6.245IleAsn: 6.245 ± 3.962
2.342IlePro: 2.342 ± 0.95
1.561IleGln: 1.561 ± 0.825
3.123IleArg: 3.123 ± 1.506
4.684IleSer: 4.684 ± 2.242
4.684IleThr: 4.684 ± 2.378
7.026IleVal: 7.026 ± 1.922
0.781IleTrp: 0.781 ± 0.659
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.781LysAla: 0.781 ± 0.659
0.781LysCys: 0.781 ± 0.677
3.123LysAsp: 3.123 ± 1.518
3.903LysGlu: 3.903 ± 1.504
3.123LysPhe: 3.123 ± 1.167
1.561LysGly: 1.561 ± 1.354
0.781LysHis: 0.781 ± 0.659
1.561LysIle: 1.561 ± 0.983
8.587LysLys: 8.587 ± 1.962
3.903LysLeu: 3.903 ± 1.175
0.781LysMet: 0.781 ± 1.148
4.684LysAsn: 4.684 ± 1.66
1.561LysPro: 1.561 ± 0.824
0.781LysGln: 0.781 ± 0.773
6.245LysArg: 6.245 ± 2.794
3.903LysSer: 3.903 ± 1.372
7.026LysThr: 7.026 ± 1.363
5.464LysVal: 5.464 ± 2.182
1.561LysTrp: 1.561 ± 1.061
4.684LysTyr: 4.684 ± 1.907
0.0LysXaa: 0.0 ± 0.0
Leu
4.684LeuAla: 4.684 ± 1.392
2.342LeuCys: 2.342 ± 1.205
3.903LeuAsp: 3.903 ± 1.943
5.464LeuGlu: 5.464 ± 2.267
3.903LeuPhe: 3.903 ± 1.736
5.464LeuGly: 5.464 ± 2.58
1.561LeuHis: 1.561 ± 0.957
7.806LeuIle: 7.806 ± 2.708
10.929LeuLys: 10.929 ± 2.367
8.587LeuLeu: 8.587 ± 2.458
1.561LeuMet: 1.561 ± 1.035
4.684LeuAsn: 4.684 ± 1.57
3.123LeuPro: 3.123 ± 1.263
4.684LeuGln: 4.684 ± 1.897
5.464LeuArg: 5.464 ± 1.335
4.684LeuSer: 4.684 ± 1.014
1.561LeuThr: 1.561 ± 1.021
6.245LeuVal: 6.245 ± 1.698
1.561LeuTrp: 1.561 ± 1.096
4.684LeuTyr: 4.684 ± 1.244
0.0LeuXaa: 0.0 ± 0.0
Met
2.342MetAla: 2.342 ± 1.061
0.781MetCys: 0.781 ± 0.694
1.561MetAsp: 1.561 ± 0.957
3.903MetGlu: 3.903 ± 1.789
1.561MetPhe: 1.561 ± 0.85
0.781MetGly: 0.781 ± 0.773
0.0MetHis: 0.0 ± 0.0
3.123MetIle: 3.123 ± 1.769
7.026MetLys: 7.026 ± 2.852
2.342MetLeu: 2.342 ± 1.279
0.781MetMet: 0.781 ± 0.694
0.781MetAsn: 0.781 ± 0.659
0.781MetPro: 0.781 ± 0.696
0.0MetGln: 0.0 ± 0.0
1.561MetArg: 1.561 ± 1.004
0.781MetSer: 0.781 ± 0.836
0.0MetThr: 0.0 ± 0.0
2.342MetVal: 2.342 ± 1.457
0.0MetTrp: 0.0 ± 0.0
0.781MetTyr: 0.781 ± 0.677
0.0MetXaa: 0.0 ± 0.0
Asn
3.123AsnAla: 3.123 ± 1.78
2.342AsnCys: 2.342 ± 1.72
3.123AsnAsp: 3.123 ± 1.444
2.342AsnGlu: 2.342 ± 1.312
0.781AsnPhe: 0.781 ± 0.659
3.123AsnGly: 3.123 ± 1.422
0.781AsnHis: 0.781 ± 0.696
1.561AsnIle: 1.561 ± 0.825
2.342AsnLys: 2.342 ± 1.191
2.342AsnLeu: 2.342 ± 1.113
3.123AsnMet: 3.123 ± 1.382
3.123AsnAsn: 3.123 ± 1.398
3.123AsnPro: 3.123 ± 1.802
1.561AsnGln: 1.561 ± 1.061
1.561AsnArg: 1.561 ± 1.172
0.781AsnSer: 0.781 ± 0.796
4.684AsnThr: 4.684 ± 1.248
3.123AsnVal: 3.123 ± 1.606
3.123AsnTrp: 3.123 ± 2.136
3.123AsnTyr: 3.123 ± 1.027
0.0AsnXaa: 0.0 ± 0.0
Pro
0.781ProAla: 0.781 ± 0.677
0.0ProCys: 0.0 ± 0.0
0.781ProAsp: 0.781 ± 0.837
2.342ProGlu: 2.342 ± 1.159
3.123ProPhe: 3.123 ± 1.264
2.342ProGly: 2.342 ± 1.056
0.0ProHis: 0.0 ± 0.0
4.684ProIle: 4.684 ± 1.499
0.0ProLys: 0.0 ± 0.0
3.123ProLeu: 3.123 ± 0.911
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
0.0ProPro: 0.0 ± 0.0
1.561ProGln: 1.561 ± 0.85
3.123ProArg: 3.123 ± 1.419
3.903ProSer: 3.903 ± 1.442
1.561ProThr: 1.561 ± 1.004
1.561ProVal: 1.561 ± 1.03
1.561ProTrp: 1.561 ± 1.317
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.561GlnAla: 1.561 ± 1.674
0.781GlnCys: 0.781 ± 0.694
2.342GlnAsp: 2.342 ± 1.279
2.342GlnGlu: 2.342 ± 1.353
0.781GlnPhe: 0.781 ± 0.773
3.123GlnGly: 3.123 ± 2.635
2.342GlnHis: 2.342 ± 1.191
1.561GlnIle: 1.561 ± 0.94
0.781GlnLys: 0.781 ± 0.696
3.123GlnLeu: 3.123 ± 0.911
0.781GlnMet: 0.781 ± 0.836
0.0GlnAsn: 0.0 ± 0.0
0.781GlnPro: 0.781 ± 0.837
0.781GlnGln: 0.781 ± 0.694
2.342GlnArg: 2.342 ± 1.134
3.123GlnSer: 3.123 ± 1.198
1.561GlnThr: 1.561 ± 0.824
2.342GlnVal: 2.342 ± 0.975
0.0GlnTrp: 0.0 ± 0.0
1.561GlnTyr: 1.561 ± 0.895
0.0GlnXaa: 0.0 ± 0.0
Arg
1.561ArgAla: 1.561 ± 0.957
0.781ArgCys: 0.781 ± 0.773
2.342ArgAsp: 2.342 ± 1.223
6.245ArgGlu: 6.245 ± 1.959
1.561ArgPhe: 1.561 ± 1.07
3.123ArgGly: 3.123 ± 1.328
1.561ArgHis: 1.561 ± 1.03
3.123ArgIle: 3.123 ± 1.951
5.464ArgLys: 5.464 ± 1.568
8.587ArgLeu: 8.587 ± 3.185
1.561ArgMet: 1.561 ± 0.889
1.561ArgAsn: 1.561 ± 1.03
3.123ArgPro: 3.123 ± 1.39
1.561ArgGln: 1.561 ± 0.98
8.587ArgArg: 8.587 ± 1.441
3.123ArgSer: 3.123 ± 1.347
3.903ArgThr: 3.903 ± 1.188
4.684ArgVal: 4.684 ± 2.049
0.0ArgTrp: 0.0 ± 0.0
2.342ArgTyr: 2.342 ± 1.681
0.0ArgXaa: 0.0 ± 0.0
Ser
3.903SerAla: 3.903 ± 1.925
4.684SerCys: 4.684 ± 1.996
3.903SerAsp: 3.903 ± 1.219
2.342SerGlu: 2.342 ± 1.418
3.123SerPhe: 3.123 ± 1.422
5.464SerGly: 5.464 ± 1.887
0.0SerHis: 0.0 ± 0.0
1.561SerIle: 1.561 ± 1.101
1.561SerLys: 1.561 ± 1.12
8.587SerLeu: 8.587 ± 2.446
3.903SerMet: 3.903 ± 1.63
3.903SerAsn: 3.903 ± 1.548
2.342SerPro: 2.342 ± 0.932
4.684SerGln: 4.684 ± 1.768
3.123SerArg: 3.123 ± 1.182
8.587SerSer: 8.587 ± 4.221
3.903SerThr: 3.903 ± 1.768
7.026SerVal: 7.026 ± 2.119
0.0SerTrp: 0.0 ± 0.0
2.342SerTyr: 2.342 ± 1.632
0.0SerXaa: 0.0 ± 0.0
Thr
1.561ThrAla: 1.561 ± 0.824
1.561ThrCys: 1.561 ± 0.964
0.0ThrAsp: 0.0 ± 0.0
3.123ThrGlu: 3.123 ± 1.522
0.781ThrPhe: 0.781 ± 0.694
2.342ThrGly: 2.342 ± 1.445
0.781ThrHis: 0.781 ± 0.694
1.561ThrIle: 1.561 ± 1.035
1.561ThrLys: 1.561 ± 0.976
5.464ThrLeu: 5.464 ± 1.455
1.561ThrMet: 1.561 ± 1.04
0.0ThrAsn: 0.0 ± 0.0
3.123ThrPro: 3.123 ± 0.984
1.561ThrGln: 1.561 ± 0.824
4.684ThrArg: 4.684 ± 1.48
5.464ThrSer: 5.464 ± 1.503
1.561ThrThr: 1.561 ± 0.889
3.903ThrVal: 3.903 ± 1.193
0.781ThrTrp: 0.781 ± 0.659
1.561ThrTyr: 1.561 ± 0.782
0.0ThrXaa: 0.0 ± 0.0
Val
2.342ValAla: 2.342 ± 1.536
3.123ValCys: 3.123 ± 1.547
3.123ValAsp: 3.123 ± 1.398
5.464ValGlu: 5.464 ± 1.433
2.342ValPhe: 2.342 ± 1.445
0.781ValGly: 0.781 ± 0.773
2.342ValHis: 2.342 ± 1.004
6.245ValIle: 6.245 ± 2.337
5.464ValLys: 5.464 ± 2.106
12.49ValLeu: 12.49 ± 3.373
4.684ValMet: 4.684 ± 1.86
4.684ValAsn: 4.684 ± 1.862
1.561ValPro: 1.561 ± 0.983
0.0ValGln: 0.0 ± 0.0
2.342ValArg: 2.342 ± 1.113
4.684ValSer: 4.684 ± 1.855
0.0ValThr: 0.0 ± 0.0
6.245ValVal: 6.245 ± 2.774
0.0ValTrp: 0.0 ± 0.0
5.464ValTyr: 5.464 ± 1.557
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.781TrpCys: 0.781 ± 0.659
1.561TrpAsp: 1.561 ± 0.98
2.342TrpGlu: 2.342 ± 1.333
0.781TrpPhe: 0.781 ± 0.694
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.781TrpIle: 0.781 ± 0.696
0.0TrpLys: 0.0 ± 0.0
0.781TrpLeu: 0.781 ± 0.837
0.781TrpMet: 0.781 ± 0.659
0.781TrpAsn: 0.781 ± 0.677
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.781TrpArg: 0.781 ± 0.773
2.342TrpSer: 2.342 ± 1.517
0.0TrpThr: 0.0 ± 0.0
1.561TrpVal: 1.561 ± 0.98
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.903TyrAla: 3.903 ± 2.068
0.0TyrCys: 0.0 ± 0.0
2.342TyrAsp: 2.342 ± 1.632
1.561TyrGlu: 1.561 ± 0.94
0.781TyrPhe: 0.781 ± 0.773
5.464TyrGly: 5.464 ± 1.611
2.342TyrHis: 2.342 ± 1.018
3.123TyrIle: 3.123 ± 1.198
1.561TyrLys: 1.561 ± 0.889
6.245TyrLeu: 6.245 ± 2.06
0.781TyrMet: 0.781 ± 0.837
0.781TyrAsn: 0.781 ± 0.796
1.561TyrPro: 1.561 ± 0.952
3.123TyrGln: 3.123 ± 1.559
2.342TyrArg: 2.342 ± 1.018
3.903TyrSer: 3.903 ± 1.321
1.561TyrThr: 1.561 ± 1.354
3.903TyrVal: 3.903 ± 1.11
0.0TyrTrp: 0.0 ± 0.0
2.342TyrTyr: 2.342 ± 1.107
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1282 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski