Amino acid dipepetide frequency for Beihai picorna-like virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.515AlaAla: 6.515 ± 0.715
1.221AlaCys: 1.221 ± 0.645
3.257AlaAsp: 3.257 ± 1.027
3.257AlaGlu: 3.257 ± 0.335
3.664AlaPhe: 3.664 ± 0.835
4.072AlaGly: 4.072 ± 1.312
2.036AlaHis: 2.036 ± 1.074
4.886AlaIle: 4.886 ± 0.19
3.664AlaLys: 3.664 ± 0.55
9.772AlaLeu: 9.772 ± 1.004
0.814AlaMet: 0.814 ± 0.241
4.479AlaAsn: 4.479 ± 1.097
5.7AlaPro: 5.7 ± 1.837
3.257AlaGln: 3.257 ± 0.335
4.072AlaArg: 4.072 ± 0.765
5.7AlaSer: 5.7 ± 1.144
4.072AlaThr: 4.072 ± 1.312
4.072AlaVal: 4.072 ± 1.312
0.814AlaTrp: 0.814 ± 0.954
3.257AlaTyr: 3.257 ± 0.335
0.0AlaXaa: 0.0 ± 0.0
Cys
1.629CysAla: 1.629 ± 0.86
0.0CysCys: 0.0 ± 0.0
0.407CysAsp: 0.407 ± 0.215
1.629CysGlu: 1.629 ± 0.86
0.407CysPhe: 0.407 ± 0.215
1.629CysGly: 1.629 ± 0.86
0.407CysHis: 0.407 ± 0.215
0.814CysIle: 0.814 ± 0.43
1.221CysLys: 1.221 ± 0.645
1.221CysLeu: 1.221 ± 0.047
0.407CysMet: 0.407 ± 0.215
1.629CysAsn: 1.629 ± 0.167
1.221CysPro: 1.221 ± 0.645
0.407CysGln: 0.407 ± 0.215
0.0CysArg: 0.0 ± 0.0
1.221CysSer: 1.221 ± 0.74
0.407CysThr: 0.407 ± 0.215
0.814CysVal: 0.814 ± 0.43
0.0CysTrp: 0.0 ± 0.0
0.407CysTyr: 0.407 ± 0.215
0.0CysXaa: 0.0 ± 0.0
Asp
3.257AspAla: 3.257 ± 0.357
0.407AspCys: 0.407 ± 0.215
3.664AspAsp: 3.664 ± 0.55
5.7AspGlu: 5.7 ± 0.24
4.072AspPhe: 4.072 ± 0.62
4.479AspGly: 4.479 ± 0.979
0.0AspHis: 0.0 ± 0.0
6.107AspIle: 6.107 ± 1.622
4.072AspLys: 4.072 ± 0.765
5.7AspLeu: 5.7 ± 1.624
1.629AspMet: 1.629 ± 0.167
2.036AspAsn: 2.036 ± 1.694
2.85AspPro: 2.85 ± 0.572
2.036AspGln: 2.036 ± 1.074
1.629AspArg: 1.629 ± 0.167
4.886AspSer: 4.886 ± 1.194
4.072AspThr: 4.072 ± 1.312
3.664AspVal: 3.664 ± 0.55
1.221AspTrp: 1.221 ± 0.047
2.036AspTyr: 2.036 ± 1.074
0.0AspXaa: 0.0 ± 0.0
Glu
3.664GluAla: 3.664 ± 0.142
1.221GluCys: 1.221 ± 0.645
4.479GluAsp: 4.479 ± 1.789
2.443GluGlu: 2.443 ± 0.597
2.443GluPhe: 2.443 ± 0.787
2.036GluGly: 2.036 ± 1.074
0.407GluHis: 0.407 ± 0.215
3.257GluIle: 3.257 ± 0.335
5.293GluLys: 5.293 ± 2.793
8.143GluLeu: 8.143 ± 0.145
1.629GluMet: 1.629 ± 0.157
2.85GluAsn: 2.85 ± 0.812
1.221GluPro: 1.221 ± 0.047
3.257GluGln: 3.257 ± 0.357
1.221GluArg: 1.221 ± 0.047
4.072GluSer: 4.072 ± 0.765
2.036GluThr: 2.036 ± 0.382
5.7GluVal: 5.7 ± 1.624
1.629GluTrp: 1.629 ± 0.86
2.036GluTyr: 2.036 ± 1.002
0.0GluXaa: 0.0 ± 0.0
Phe
3.664PheAla: 3.664 ± 0.142
0.407PheCys: 0.407 ± 0.215
3.257PheAsp: 3.257 ± 1.049
2.443PheGlu: 2.443 ± 0.095
1.629PhePhe: 1.629 ± 0.167
2.85PheGly: 2.85 ± 1.264
1.221PheHis: 1.221 ± 0.645
2.036PheIle: 2.036 ± 0.382
4.072PheLys: 4.072 ± 2.149
4.072PheLeu: 4.072 ± 0.072
0.814PheMet: 0.814 ± 0.262
2.036PheAsn: 2.036 ± 0.382
3.664PhePro: 3.664 ± 0.55
2.036PheGln: 2.036 ± 0.31
2.85PheArg: 2.85 ± 0.572
2.036PheSer: 2.036 ± 0.31
2.443PheThr: 2.443 ± 1.289
3.257PheVal: 3.257 ± 0.357
0.814PheTrp: 0.814 ± 0.262
1.221PheTyr: 1.221 ± 0.74
0.0PheXaa: 0.0 ± 0.0
Gly
4.479GlyAla: 4.479 ± 0.287
0.814GlyCys: 0.814 ± 0.262
4.886GlyAsp: 4.886 ± 1.194
3.664GlyGlu: 3.664 ± 1.527
1.629GlyPhe: 1.629 ± 0.167
6.922GlyGly: 6.922 ± 2.576
1.629GlyHis: 1.629 ± 0.525
2.85GlyIle: 2.85 ± 1.504
5.293GlyLys: 5.293 ± 2.101
3.664GlyLeu: 3.664 ± 0.835
0.814GlyMet: 0.814 ± 0.43
2.85GlyAsn: 2.85 ± 0.572
2.036GlyPro: 2.036 ± 1.002
2.036GlyGln: 2.036 ± 1.002
2.443GlyArg: 2.443 ± 0.095
7.329GlySer: 7.329 ± 2.361
3.257GlyThr: 3.257 ± 1.049
6.515GlyVal: 6.515 ± 2.054
0.407GlyTrp: 0.407 ± 0.477
2.85GlyTyr: 2.85 ± 0.812
0.0GlyXaa: 0.0 ± 0.0
His
2.036HisAla: 2.036 ± 0.31
0.0HisCys: 0.0 ± 0.0
0.407HisAsp: 0.407 ± 0.477
1.629HisGlu: 1.629 ± 0.86
2.036HisPhe: 2.036 ± 0.382
2.036HisGly: 2.036 ± 1.074
0.0HisHis: 0.0 ± 0.0
1.221HisIle: 1.221 ± 0.645
1.221HisLys: 1.221 ± 0.047
2.85HisLeu: 2.85 ± 0.812
0.407HisMet: 0.407 ± 0.215
0.814HisAsn: 0.814 ± 0.262
0.814HisPro: 0.814 ± 0.262
0.814HisGln: 0.814 ± 0.262
0.814HisArg: 0.814 ± 0.262
0.814HisSer: 0.814 ± 0.43
2.036HisThr: 2.036 ± 0.382
0.814HisVal: 0.814 ± 0.43
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.886IleAla: 4.886 ± 1.574
0.407IleCys: 0.407 ± 0.215
6.515IleAsp: 6.515 ± 1.362
3.664IleGlu: 3.664 ± 1.242
3.257IlePhe: 3.257 ± 1.027
2.443IleGly: 2.443 ± 1.479
1.629IleHis: 1.629 ± 0.167
2.443IleIle: 2.443 ± 0.597
2.85IleLys: 2.85 ± 0.812
2.036IleLeu: 2.036 ± 0.382
0.814IleMet: 0.814 ± 0.43
2.443IleAsn: 2.443 ± 0.597
2.443IlePro: 2.443 ± 0.597
0.814IleGln: 0.814 ± 0.262
2.443IleArg: 2.443 ± 1.289
4.886IleSer: 4.886 ± 2.266
4.886IleThr: 4.886 ± 2.266
4.479IleVal: 4.479 ± 0.287
0.407IleTrp: 0.407 ± 0.215
1.629IleTyr: 1.629 ± 0.167
0.0IleXaa: 0.0 ± 0.0
Lys
4.886LysAla: 4.886 ± 0.502
2.443LysCys: 2.443 ± 1.289
5.293LysAsp: 5.293 ± 2.101
2.85LysGlu: 2.85 ± 1.504
4.072LysPhe: 4.072 ± 1.457
4.886LysGly: 4.886 ± 1.886
2.443LysHis: 2.443 ± 1.289
3.664LysIle: 3.664 ± 0.55
6.515LysLys: 6.515 ± 0.67
3.257LysLeu: 3.257 ± 0.335
1.629LysMet: 1.629 ± 0.167
3.664LysAsn: 3.664 ± 1.242
2.85LysPro: 2.85 ± 1.264
1.629LysGln: 1.629 ± 0.86
4.072LysArg: 4.072 ± 2.149
4.886LysSer: 4.886 ± 2.579
2.036LysThr: 2.036 ± 1.074
2.443LysVal: 2.443 ± 0.597
1.629LysTrp: 1.629 ± 0.167
1.629LysTyr: 1.629 ± 0.167
0.0LysXaa: 0.0 ± 0.0
Leu
8.958LeuAla: 8.958 ± 0.118
3.257LeuCys: 3.257 ± 1.719
6.107LeuAsp: 6.107 ± 0.237
6.515LeuGlu: 6.515 ± 2.054
3.257LeuPhe: 3.257 ± 1.027
4.479LeuGly: 4.479 ± 0.405
2.443LeuHis: 2.443 ± 1.289
3.257LeuIle: 3.257 ± 0.357
2.85LeuLys: 2.85 ± 1.504
5.293LeuLeu: 5.293 ± 0.025
0.814LeuMet: 0.814 ± 0.43
2.036LeuAsn: 2.036 ± 1.002
2.443LeuPro: 2.443 ± 0.597
2.036LeuGln: 2.036 ± 1.074
5.7LeuArg: 5.7 ± 0.24
6.922LeuSer: 6.922 ± 1.192
6.515LeuThr: 6.515 ± 0.715
6.107LeuVal: 6.107 ± 0.237
1.221LeuTrp: 1.221 ± 0.047
1.221LeuTyr: 1.221 ± 0.645
0.0LeuXaa: 0.0 ± 0.0
Met
0.407MetAla: 0.407 ± 0.215
0.407MetCys: 0.407 ± 0.215
0.0MetAsp: 0.0 ± 0.0
1.221MetGlu: 1.221 ± 0.645
0.407MetPhe: 0.407 ± 0.215
2.036MetGly: 2.036 ± 1.002
0.0MetHis: 0.0 ± 0.0
3.257MetIle: 3.257 ± 0.357
2.443MetLys: 2.443 ± 0.597
2.85MetLeu: 2.85 ± 0.572
0.814MetMet: 0.814 ± 0.43
0.814MetAsn: 0.814 ± 0.43
1.629MetPro: 1.629 ± 0.86
0.0MetGln: 0.0 ± 0.0
2.443MetArg: 2.443 ± 0.597
0.407MetSer: 0.407 ± 0.215
1.629MetThr: 1.629 ± 0.86
2.036MetVal: 2.036 ± 0.31
0.407MetTrp: 0.407 ± 0.215
0.407MetTyr: 0.407 ± 0.215
0.0MetXaa: 0.0 ± 0.0
Asn
4.072AsnAla: 4.072 ± 0.62
0.407AsnCys: 0.407 ± 0.215
3.257AsnAsp: 3.257 ± 0.357
2.036AsnGlu: 2.036 ± 1.002
1.629AsnPhe: 1.629 ± 0.525
3.664AsnGly: 3.664 ± 0.835
0.814AsnHis: 0.814 ± 0.43
2.443AsnIle: 2.443 ± 0.095
1.629AsnLys: 1.629 ± 0.86
4.072AsnLeu: 4.072 ± 0.62
1.221AsnMet: 1.221 ± 0.047
3.664AsnAsn: 3.664 ± 0.142
3.257AsnPro: 3.257 ± 1.049
2.443AsnGln: 2.443 ± 0.095
2.036AsnArg: 2.036 ± 0.382
3.664AsnSer: 3.664 ± 0.835
3.257AsnThr: 3.257 ± 1.742
2.443AsnVal: 2.443 ± 0.787
0.814AsnTrp: 0.814 ± 0.262
1.629AsnTyr: 1.629 ± 0.525
0.0AsnXaa: 0.0 ± 0.0
Pro
3.664ProAla: 3.664 ± 0.142
0.407ProCys: 0.407 ± 0.477
2.036ProAsp: 2.036 ± 1.074
2.85ProGlu: 2.85 ± 1.956
2.443ProPhe: 2.443 ± 0.787
2.036ProGly: 2.036 ± 1.002
0.407ProHis: 0.407 ± 0.477
2.036ProIle: 2.036 ± 0.31
4.072ProLys: 4.072 ± 2.149
4.479ProLeu: 4.479 ± 0.979
1.629ProMet: 1.629 ± 0.167
1.221ProAsn: 1.221 ± 1.432
0.407ProPro: 0.407 ± 0.215
1.221ProGln: 1.221 ± 0.74
2.036ProArg: 2.036 ± 0.31
3.664ProSer: 3.664 ± 0.142
5.293ProThr: 5.293 ± 2.051
1.629ProVal: 1.629 ± 0.525
0.407ProTrp: 0.407 ± 0.215
3.664ProTyr: 3.664 ± 2.219
0.0ProXaa: 0.0 ± 0.0
Gln
3.664GlnAla: 3.664 ± 0.55
0.407GlnCys: 0.407 ± 0.215
2.443GlnAsp: 2.443 ± 0.095
1.221GlnGlu: 1.221 ± 0.645
1.221GlnPhe: 1.221 ± 0.74
2.85GlnGly: 2.85 ± 0.572
0.814GlnHis: 0.814 ± 0.43
2.036GlnIle: 2.036 ± 0.382
1.629GlnLys: 1.629 ± 0.167
2.443GlnLeu: 2.443 ± 0.095
0.814GlnMet: 0.814 ± 0.43
0.814GlnAsn: 0.814 ± 0.43
0.407GlnPro: 0.407 ± 0.215
3.257GlnGln: 3.257 ± 0.357
1.629GlnArg: 1.629 ± 1.217
2.85GlnSer: 2.85 ± 0.572
0.814GlnThr: 0.814 ± 0.43
3.257GlnVal: 3.257 ± 1.049
0.0GlnTrp: 0.0 ± 0.0
0.407GlnTyr: 0.407 ± 0.477
0.0GlnXaa: 0.0 ± 0.0
Arg
3.664ArgAla: 3.664 ± 0.142
0.814ArgCys: 0.814 ± 0.43
2.85ArgAsp: 2.85 ± 0.12
3.664ArgGlu: 3.664 ± 0.55
2.036ArgPhe: 2.036 ± 0.31
3.664ArgGly: 3.664 ± 0.835
2.036ArgHis: 2.036 ± 0.31
4.072ArgIle: 4.072 ± 0.62
4.479ArgLys: 4.479 ± 2.364
2.443ArgLeu: 2.443 ± 0.597
1.629ArgMet: 1.629 ± 0.167
1.221ArgAsn: 1.221 ± 0.047
1.629ArgPro: 1.629 ± 1.217
0.407ArgGln: 0.407 ± 0.215
4.479ArgArg: 4.479 ± 0.405
0.814ArgSer: 0.814 ± 0.262
2.443ArgThr: 2.443 ± 0.787
2.443ArgVal: 2.443 ± 0.597
0.407ArgTrp: 0.407 ± 0.215
2.443ArgTyr: 2.443 ± 0.787
0.0ArgXaa: 0.0 ± 0.0
Ser
6.515SerAla: 6.515 ± 1.407
0.814SerCys: 0.814 ± 0.43
4.479SerAsp: 4.479 ± 1.097
4.479SerGlu: 4.479 ± 0.405
2.036SerPhe: 2.036 ± 1.002
6.515SerGly: 6.515 ± 0.715
1.221SerHis: 1.221 ± 0.047
4.072SerIle: 4.072 ± 0.765
5.7SerLys: 5.7 ± 0.932
6.922SerLeu: 6.922 ± 1.577
3.257SerMet: 3.257 ± 0.335
4.072SerAsn: 4.072 ± 2.004
2.85SerPro: 2.85 ± 0.12
2.036SerGln: 2.036 ± 1.002
1.629SerArg: 1.629 ± 1.217
2.036SerSer: 2.036 ± 0.382
4.886SerThr: 4.886 ± 0.882
4.479SerVal: 4.479 ± 0.287
0.0SerTrp: 0.0 ± 0.0
2.443SerTyr: 2.443 ± 1.479
0.0SerXaa: 0.0 ± 0.0
Thr
4.072ThrAla: 4.072 ± 0.62
0.0ThrCys: 0.0 ± 0.0
3.664ThrAsp: 3.664 ± 2.219
2.85ThrGlu: 2.85 ± 0.12
4.072ThrPhe: 4.072 ± 0.62
2.85ThrGly: 2.85 ± 1.504
0.407ThrHis: 0.407 ± 0.215
4.479ThrIle: 4.479 ± 0.405
4.479ThrLys: 4.479 ± 0.287
3.664ThrLeu: 3.664 ± 0.835
1.221ThrMet: 1.221 ± 0.645
4.479ThrAsn: 4.479 ± 1.789
4.072ThrPro: 4.072 ± 2.004
1.629ThrGln: 1.629 ± 0.167
2.443ThrArg: 2.443 ± 0.787
4.479ThrSer: 4.479 ± 1.789
4.886ThrThr: 4.886 ± 2.266
4.886ThrVal: 4.886 ± 0.502
0.814ThrTrp: 0.814 ± 0.43
1.629ThrTyr: 1.629 ± 0.525
0.0ThrXaa: 0.0 ± 0.0
Val
6.107ValAla: 6.107 ± 0.237
1.221ValCys: 1.221 ± 0.047
2.85ValAsp: 2.85 ± 0.812
4.072ValGlu: 4.072 ± 1.457
4.072ValPhe: 4.072 ± 1.457
4.479ValGly: 4.479 ± 1.672
1.629ValHis: 1.629 ± 0.167
1.221ValIle: 1.221 ± 0.645
3.664ValLys: 3.664 ± 0.835
4.479ValLeu: 4.479 ± 1.672
1.221ValMet: 1.221 ± 0.74
3.664ValAsn: 3.664 ± 0.55
4.072ValPro: 4.072 ± 2.004
0.814ValGln: 0.814 ± 0.262
4.886ValArg: 4.886 ± 0.882
5.293ValSer: 5.293 ± 0.025
4.479ValThr: 4.479 ± 0.405
3.664ValVal: 3.664 ± 0.142
1.629ValTrp: 1.629 ± 0.525
4.072ValTyr: 4.072 ± 1.312
0.0ValXaa: 0.0 ± 0.0
Trp
1.629TrpAla: 1.629 ± 0.525
0.407TrpCys: 0.407 ± 0.215
2.443TrpAsp: 2.443 ± 0.597
0.0TrpGlu: 0.0 ± 0.0
0.407TrpPhe: 0.407 ± 0.215
0.407TrpGly: 0.407 ± 0.215
0.407TrpHis: 0.407 ± 0.477
0.0TrpIle: 0.0 ± 0.0
0.407TrpLys: 0.407 ± 0.215
0.814TrpLeu: 0.814 ± 0.43
0.0TrpMet: 0.0 ± 0.0
0.407TrpAsn: 0.407 ± 0.477
1.221TrpPro: 1.221 ± 0.74
2.036TrpGln: 2.036 ± 0.31
0.407TrpArg: 0.407 ± 0.215
0.814TrpSer: 0.814 ± 0.262
0.0TrpThr: 0.0 ± 0.0
1.221TrpVal: 1.221 ± 0.047
0.407TrpTrp: 0.407 ± 0.215
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.221TyrAla: 1.221 ± 0.047
0.814TyrCys: 0.814 ± 0.262
1.221TyrAsp: 1.221 ± 0.645
2.85TyrGlu: 2.85 ± 0.12
2.036TyrPhe: 2.036 ± 0.382
2.036TyrGly: 2.036 ± 1.002
0.814TyrHis: 0.814 ± 0.954
1.221TyrIle: 1.221 ± 0.74
1.221TyrLys: 1.221 ± 0.645
3.257TyrLeu: 3.257 ± 0.357
1.629TyrMet: 1.629 ± 0.167
3.257TyrAsn: 3.257 ± 1.742
0.814TyrPro: 0.814 ± 0.43
0.814TyrGln: 0.814 ± 0.262
0.407TyrArg: 0.407 ± 0.477
3.664TyrSer: 3.664 ± 0.142
1.629TyrThr: 1.629 ± 0.167
3.664TyrVal: 3.664 ± 1.527
0.407TyrTrp: 0.407 ± 0.477
1.629TyrTyr: 1.629 ± 1.909
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2457 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski