Amino acid dipepetide frequency for Psathyrella aberdarensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.256AlaAla: 8.256 ± 0.056	0.982AlaCys: 0.982 ± 0.013	3.867AlaAsp: 3.867 ± 0.025	4.97AlaGlu: 4.97 ± 0.034	3.103AlaPhe: 3.103 ± 0.025	5.301AlaGly: 5.301 ± 0.036	1.832AlaHis: 1.832 ± 0.016	4.385AlaIle: 4.385 ± 0.027	4.139AlaLys: 4.139 ± 0.029	8.226AlaLeu: 8.226 ± 0.041	1.664AlaMet: 1.664 ± 0.016	2.882AlaAsn: 2.882 ± 0.021	5.01AlaPro: 5.01 ± 0.039	3.323AlaGln: 3.323 ± 0.025	4.605AlaArg: 4.605 ± 0.027	7.366AlaSer: 7.366 ± 0.038	5.139AlaThr: 5.139 ± 0.036	5.114AlaVal: 5.114 ± 0.028	1.026AlaTrp: 1.026 ± 0.013	2.155AlaTyr: 2.155 ± 0.018	0.032AlaXaa: 0.032 ± 0.002
Cys	0.844CysAla: 0.844 ± 0.012	0.215CysCys: 0.215 ± 0.006	0.671CysAsp: 0.671 ± 0.01	0.595CysGlu: 0.595 ± 0.009	0.543CysPhe: 0.543 ± 0.008	0.767CysGly: 0.767 ± 0.013	0.37CysHis: 0.37 ± 0.008	0.64CysIle: 0.64 ± 0.009	0.521CysLys: 0.521 ± 0.009	1.176CysLeu: 1.176 ± 0.014	0.26CysMet: 0.26 ± 0.006	0.421CysAsn: 0.421 ± 0.009	0.722CysPro: 0.722 ± 0.012	0.448CysGln: 0.448 ± 0.009	0.692CysArg: 0.692 ± 0.011	0.902CysSer: 0.902 ± 0.012	0.669CysThr: 0.669 ± 0.011	0.682CysVal: 0.682 ± 0.01	0.175CysTrp: 0.175 ± 0.005	0.32CysTyr: 0.32 ± 0.006	0.005CysXaa: 0.005 ± 0.001
Asp	4.597AspAla: 4.597 ± 0.028	0.574AspCys: 0.574 ± 0.008	4.474AspAsp: 4.474 ± 0.037	4.716AspGlu: 4.716 ± 0.035	2.29AspPhe: 2.29 ± 0.018	4.101AspGly: 4.101 ± 0.024	1.326AspHis: 1.326 ± 0.014	3.215AspIle: 3.215 ± 0.023	2.329AspLys: 2.329 ± 0.021	5.329AspLeu: 5.329 ± 0.03	1.174AspMet: 1.174 ± 0.013	1.877AspAsn: 1.877 ± 0.018	3.619AspPro: 3.619 ± 0.025	1.803AspGln: 1.803 ± 0.016	3.064AspArg: 3.064 ± 0.024	4.354AspSer: 4.354 ± 0.029	2.877AspThr: 2.877 ± 0.02	3.758AspVal: 3.758 ± 0.027	0.886AspTrp: 0.886 ± 0.012	1.534AspTyr: 1.534 ± 0.016	0.025AspXaa: 0.025 ± 0.002
Glu	5.506GluAla: 5.506 ± 0.039	0.763GluCys: 0.763 ± 0.011	4.731GluAsp: 4.731 ± 0.034	6.235GluGlu: 6.235 ± 0.058	2.083GluPhe: 2.083 ± 0.017	3.979GluGly: 3.979 ± 0.027	1.494GluHis: 1.494 ± 0.017	3.049GluIle: 3.049 ± 0.023	3.65GluLys: 3.65 ± 0.03	5.763GluLeu: 5.763 ± 0.036	1.274GluMet: 1.274 ± 0.013	2.154GluAsn: 2.154 ± 0.019	2.807GluPro: 2.807 ± 0.025	2.376GluGln: 2.376 ± 0.023	4.102GluArg: 4.102 ± 0.034	4.23GluSer: 4.23 ± 0.031	3.141GluThr: 3.141 ± 0.024	3.793GluVal: 3.793 ± 0.024	1.007GluTrp: 1.007 ± 0.013	1.646GluTyr: 1.646 ± 0.016	0.028GluXaa: 0.028 ± 0.002
Phe	2.902PheAla: 2.902 ± 0.019	0.506PheCys: 0.506 ± 0.008	2.403PheAsp: 2.403 ± 0.021	2.314PheGlu: 2.314 ± 0.02	1.836PhePhe: 1.836 ± 0.022	2.609PheGly: 2.609 ± 0.026	0.947PheHis: 0.947 ± 0.012	2.091PheIle: 2.091 ± 0.019	1.807PheLys: 1.807 ± 0.018	3.616PheLeu: 3.616 ± 0.026	0.744PheMet: 0.744 ± 0.011	1.552PheAsn: 1.552 ± 0.015	2.046PhePro: 2.046 ± 0.021	1.369PheGln: 1.369 ± 0.015	2.023PheArg: 2.023 ± 0.017	3.198PheSer: 3.198 ± 0.025	2.133PheThr: 2.133 ± 0.02	2.513PheVal: 2.513 ± 0.02	0.59PheTrp: 0.59 ± 0.009	1.042PheTyr: 1.042 ± 0.013	0.015PheXaa: 0.015 ± 0.002
Gly	4.856GlyAla: 4.856 ± 0.035	0.793GlyCys: 0.793 ± 0.012	3.538GlyAsp: 3.538 ± 0.025	3.597GlyGlu: 3.597 ± 0.027	2.477GlyPhe: 2.477 ± 0.021	5.442GlyGly: 5.442 ± 0.056	1.591GlyHis: 1.591 ± 0.015	3.161GlyIle: 3.161 ± 0.023	3.519GlyLys: 3.519 ± 0.031	5.677GlyLeu: 5.677 ± 0.032	1.331GlyMet: 1.331 ± 0.018	2.365GlyAsn: 2.365 ± 0.022	3.315GlyPro: 3.315 ± 0.028	2.298GlyGln: 2.298 ± 0.02	3.831GlyArg: 3.831 ± 0.027	5.596GlySer: 5.596 ± 0.039	3.854GlyThr: 3.854 ± 0.033	4.069GlyVal: 4.069 ± 0.027	1.059GlyTrp: 1.059 ± 0.016	1.82GlyTyr: 1.82 ± 0.018	0.029GlyXaa: 0.029 ± 0.002
His	1.827HisAla: 1.827 ± 0.017	0.348HisCys: 0.348 ± 0.007	1.256HisAsp: 1.256 ± 0.014	1.281HisGlu: 1.281 ± 0.016	1.052HisPhe: 1.052 ± 0.013	1.572HisGly: 1.572 ± 0.014	0.888HisHis: 0.888 ± 0.013	1.394HisIle: 1.394 ± 0.015	0.925HisLys: 0.925 ± 0.013	2.673HisLeu: 2.673 ± 0.021	0.441HisMet: 0.441 ± 0.008	0.827HisAsn: 0.827 ± 0.011	1.956HisPro: 1.956 ± 0.02	1.007HisGln: 1.007 ± 0.013	1.569HisArg: 1.569 ± 0.017	1.948HisSer: 1.948 ± 0.018	1.298HisThr: 1.298 ± 0.014	1.486HisVal: 1.486 ± 0.015	0.354HisTrp: 0.354 ± 0.007	0.686HisTyr: 0.686 ± 0.01	0.007HisXaa: 0.007 ± 0.001
Ile	4.145IleAla: 4.145 ± 0.03	0.623IleCys: 0.623 ± 0.011	2.971IleAsp: 2.971 ± 0.022	2.96IleGlu: 2.96 ± 0.021	2.013IlePhe: 2.013 ± 0.02	2.854IleGly: 2.854 ± 0.021	1.289IleHis: 1.289 ± 0.015	2.52IleIle: 2.52 ± 0.021	2.193IleLys: 2.193 ± 0.02	4.864IleLeu: 4.864 ± 0.033	0.911IleMet: 0.911 ± 0.012	1.685IleAsn: 1.685 ± 0.015	3.279IlePro: 3.279 ± 0.021	2.0IleGln: 2.0 ± 0.018	2.898IleArg: 2.898 ± 0.022	3.877IleSer: 3.877 ± 0.025	2.696IleThr: 2.696 ± 0.022	3.397IleVal: 3.397 ± 0.027	0.673IleTrp: 0.673 ± 0.01	1.359IleTyr: 1.359 ± 0.014	0.017IleXaa: 0.017 ± 0.002
Lys	4.534LysAla: 4.534 ± 0.034	0.527LysCys: 0.527 ± 0.008	2.864LysAsp: 2.864 ± 0.023	3.741LysGlu: 3.741 ± 0.031	1.582LysPhe: 1.582 ± 0.017	3.105LysGly: 3.105 ± 0.023	1.172LysHis: 1.172 ± 0.013	2.28LysIle: 2.28 ± 0.022	3.61LysLys: 3.61 ± 0.035	4.395LysLeu: 4.395 ± 0.027	0.938LysMet: 0.938 ± 0.013	1.751LysAsn: 1.751 ± 0.018	2.789LysPro: 2.789 ± 0.028	1.795LysGln: 1.795 ± 0.017	3.49LysArg: 3.49 ± 0.027	3.506LysSer: 3.506 ± 0.025	2.781LysThr: 2.781 ± 0.024	2.906LysVal: 2.906 ± 0.025	0.691LysTrp: 0.691 ± 0.011	1.325LysTyr: 1.325 ± 0.016	0.024LysXaa: 0.024 ± 0.002
Leu	7.881LeuAla: 7.881 ± 0.034	1.249LeuCys: 1.249 ± 0.014	5.647LeuAsp: 5.647 ± 0.032	6.213LeuGlu: 6.213 ± 0.04	3.449LeuPhe: 3.449 ± 0.028	5.532LeuGly: 5.532 ± 0.034	2.443LeuHis: 2.443 ± 0.022	4.01LeuIle: 4.01 ± 0.027	4.948LeuLys: 4.948 ± 0.034	8.709LeuLeu: 8.709 ± 0.053	1.627LeuMet: 1.627 ± 0.018	3.482LeuAsn: 3.482 ± 0.025	6.161LeuPro: 6.161 ± 0.035	3.967LeuGln: 3.967 ± 0.026	5.953LeuArg: 5.953 ± 0.032	7.838LeuSer: 7.838 ± 0.042	5.189LeuThr: 5.189 ± 0.03	5.717LeuVal: 5.717 ± 0.034	1.215LeuTrp: 1.215 ± 0.014	2.537LeuTyr: 2.537 ± 0.02	0.032LeuXaa: 0.032 ± 0.003
Met	1.76MetAla: 1.76 ± 0.016	0.194MetCys: 0.194 ± 0.006	1.251MetAsp: 1.251 ± 0.013	1.232MetGlu: 1.232 ± 0.015	0.68MetPhe: 0.68 ± 0.011	1.192MetGly: 1.192 ± 0.015	0.47MetHis: 0.47 ± 0.009	0.845MetIle: 0.845 ± 0.011	1.03MetLys: 1.03 ± 0.013	1.725MetLeu: 1.725 ± 0.014	0.458MetMet: 0.458 ± 0.008	0.747MetAsn: 0.747 ± 0.011	1.109MetPro: 1.109 ± 0.014	0.746MetGln: 0.746 ± 0.012	1.087MetArg: 1.087 ± 0.014	1.628MetSer: 1.628 ± 0.013	1.095MetThr: 1.095 ± 0.011	1.173MetVal: 1.173 ± 0.014	0.247MetTrp: 0.247 ± 0.005	0.462MetTyr: 0.462 ± 0.009	0.007MetXaa: 0.007 ± 0.001
Asn	3.262AsnAla: 3.262 ± 0.024	0.381AsnCys: 0.381 ± 0.007	1.908AsnAsp: 1.908 ± 0.015	1.969AsnGlu: 1.969 ± 0.018	1.321AsnPhe: 1.321 ± 0.014	2.67AsnGly: 2.67 ± 0.025	0.893AsnHis: 0.893 ± 0.011	1.97AsnIle: 1.97 ± 0.019	1.498AsnLys: 1.498 ± 0.015	3.598AsnLeu: 3.598 ± 0.023	0.697AsnMet: 0.697 ± 0.011	1.465AsnAsn: 1.465 ± 0.02	2.716AsnPro: 2.716 ± 0.021	1.288AsnGln: 1.288 ± 0.016	1.93AsnArg: 1.93 ± 0.019	2.76AsnSer: 2.76 ± 0.023	2.107AsnThr: 2.107 ± 0.017	2.422AsnVal: 2.422 ± 0.02	0.505AsnTrp: 0.505 ± 0.009	0.948AsnTyr: 0.948 ± 0.012	0.015AsnXaa: 0.015 ± 0.002
Pro	5.347ProAla: 5.347 ± 0.041	0.511ProCys: 0.511 ± 0.01	3.306ProAsp: 3.306 ± 0.021	3.923ProGlu: 3.923 ± 0.028	2.403ProPhe: 2.403 ± 0.022	3.95ProGly: 3.95 ± 0.029	1.555ProHis: 1.555 ± 0.02	2.676ProIle: 2.676 ± 0.02	2.783ProLys: 2.783 ± 0.023	5.306ProLeu: 5.306 ± 0.033	0.966ProMet: 0.966 ± 0.014	2.408ProAsn: 2.408 ± 0.022	6.198ProPro: 6.198 ± 0.068	2.455ProGln: 2.455 ± 0.023	3.093ProArg: 3.093 ± 0.027	6.731ProSer: 6.731 ± 0.043	4.333ProThr: 4.333 ± 0.028	3.682ProVal: 3.682 ± 0.029	0.7ProTrp: 0.7 ± 0.009	1.514ProTyr: 1.514 ± 0.016	0.032ProXaa: 0.032 ± 0.002
Gln	3.435GlnAla: 3.435 ± 0.024	0.453GlnCys: 0.453 ± 0.009	2.092GlnAsp: 2.092 ± 0.017	2.465GlnGlu: 2.465 ± 0.022	1.358GlnPhe: 1.358 ± 0.015	2.2GlnGly: 2.2 ± 0.02	1.112GlnHis: 1.112 ± 0.014	1.78GlnIle: 1.78 ± 0.017	1.84GlnLys: 1.84 ± 0.019	3.67GlnLeu: 3.67 ± 0.025	0.827GlnMet: 0.827 ± 0.011	1.366GlnAsn: 1.366 ± 0.016	2.471GlnPro: 2.471 ± 0.027	2.337GlnGln: 2.337 ± 0.043	2.452GlnArg: 2.452 ± 0.021	2.785GlnSer: 2.785 ± 0.024	2.232GlnThr: 2.232 ± 0.02	2.219GlnVal: 2.219 ± 0.019	0.573GlnTrp: 0.573 ± 0.009	1.103GlnTyr: 1.103 ± 0.014	0.016GlnXaa: 0.016 ± 0.002
Arg	4.587ArgAla: 4.587 ± 0.028	0.756ArgCys: 0.756 ± 0.011	3.198ArgAsp: 3.198 ± 0.024	3.796ArgGlu: 3.796 ± 0.032	2.313ArgPhe: 2.313 ± 0.019	3.287ArgGly: 3.287 ± 0.023	1.453ArgHis: 1.453 ± 0.014	2.997ArgIle: 2.997 ± 0.021	3.436ArgLys: 3.436 ± 0.028	5.62ArgLeu: 5.62 ± 0.031	1.211ArgMet: 1.211 ± 0.014	2.256ArgAsn: 2.256 ± 0.018	3.369ArgPro: 3.369 ± 0.027	2.36ArgGln: 2.36 ± 0.022	4.786ArgArg: 4.786 ± 0.034	4.772ArgSer: 4.772 ± 0.03	3.258ArgThr: 3.258 ± 0.021	3.585ArgVal: 3.585 ± 0.02	0.95ArgTrp: 0.95 ± 0.013	1.706ArgTyr: 1.706 ± 0.018	0.021ArgXaa: 0.021 ± 0.002
Ser	6.574SerAla: 6.574 ± 0.036	0.804SerCys: 0.804 ± 0.012	4.556SerAsp: 4.556 ± 0.032	4.25SerGlu: 4.25 ± 0.025	3.269SerPhe: 3.269 ± 0.023	5.488SerGly: 5.488 ± 0.034	1.917SerHis: 1.917 ± 0.02	3.939SerIle: 3.939 ± 0.025	3.883SerLys: 3.883 ± 0.028	7.743SerLeu: 7.743 ± 0.043	1.552SerMet: 1.552 ± 0.015	3.113SerAsn: 3.113 ± 0.02	5.761SerPro: 5.761 ± 0.043	3.114SerGln: 3.114 ± 0.026	4.914SerArg: 4.914 ± 0.029	9.541SerSer: 9.541 ± 0.065	5.875SerThr: 5.875 ± 0.04	4.677SerVal: 4.677 ± 0.03	1.024SerTrp: 1.024 ± 0.013	1.918SerTyr: 1.918 ± 0.018	0.033SerXaa: 0.033 ± 0.003
Thr	4.886ThrAla: 4.886 ± 0.029	0.639ThrCys: 0.639 ± 0.011	2.672ThrAsp: 2.672 ± 0.018	2.934ThrGlu: 2.934 ± 0.025	2.379ThrPhe: 2.379 ± 0.019	3.811ThrGly: 3.811 ± 0.028	1.382ThrHis: 1.382 ± 0.015	3.078ThrIle: 3.078 ± 0.025	2.546ThrLys: 2.546 ± 0.02	5.825ThrLeu: 5.825 ± 0.031	1.074ThrMet: 1.074 ± 0.012	2.024ThrAsn: 2.024 ± 0.019	4.49ThrPro: 4.49 ± 0.032	2.058ThrGln: 2.058 ± 0.017	3.292ThrArg: 3.292 ± 0.024	5.391ThrSer: 5.391 ± 0.033	4.119ThrThr: 4.119 ± 0.04	3.777ThrVal: 3.777 ± 0.024	0.75ThrTrp: 0.75 ± 0.012	1.466ThrTyr: 1.466 ± 0.017	0.023ThrXaa: 0.023 ± 0.002
Val	5.088ValAla: 5.088 ± 0.025	0.766ValCys: 0.766 ± 0.012	3.907ValAsp: 3.907 ± 0.025	4.218ValGlu: 4.218 ± 0.031	2.43ValPhe: 2.43 ± 0.02	3.677ValGly: 3.677 ± 0.026	1.492ValHis: 1.492 ± 0.014	3.018ValIle: 3.018 ± 0.024	3.191ValLys: 3.191 ± 0.021	5.971ValLeu: 5.971 ± 0.035	1.158ValMet: 1.158 ± 0.014	2.277ValAsn: 2.277 ± 0.016	3.865ValPro: 3.865 ± 0.029	2.494ValGln: 2.494 ± 0.019	3.359ValArg: 3.359 ± 0.022	4.553ValSer: 4.553 ± 0.027	3.417ValThr: 3.417 ± 0.025	4.362ValVal: 4.362 ± 0.031	0.844ValTrp: 0.844 ± 0.011	1.756ValTyr: 1.756 ± 0.016	0.023ValXaa: 0.023 ± 0.002
Trp	1.03TrpAla: 1.03 ± 0.011	0.186TrpCys: 0.186 ± 0.005	0.905TrpAsp: 0.905 ± 0.012	0.873TrpGlu: 0.873 ± 0.012	0.549TrpPhe: 0.549 ± 0.009	0.823TrpGly: 0.823 ± 0.012	0.324TrpHis: 0.324 ± 0.007	0.785TrpIle: 0.785 ± 0.01	0.892TrpLys: 0.892 ± 0.011	1.232TrpLeu: 1.232 ± 0.014	0.322TrpMet: 0.322 ± 0.007	0.614TrpAsn: 0.614 ± 0.01	0.643TrpPro: 0.643 ± 0.01	0.447TrpGln: 0.447 ± 0.008	0.909TrpArg: 0.909 ± 0.013	0.987TrpSer: 0.987 ± 0.011	0.864TrpThr: 0.864 ± 0.012	0.866TrpVal: 0.866 ± 0.011	0.264TrpTrp: 0.264 ± 0.007	0.416TrpTyr: 0.416 ± 0.008	0.004TrpXaa: 0.004 ± 0.001
Tyr	2.023TyrAla: 2.023 ± 0.019	0.366TyrCys: 0.366 ± 0.008	1.679TyrAsp: 1.679 ± 0.018	1.503TyrGlu: 1.503 ± 0.014	1.111TyrPhe: 1.111 ± 0.013	1.831TyrGly: 1.831 ± 0.019	0.837TyrHis: 0.837 ± 0.012	1.375TyrIle: 1.375 ± 0.014	1.044TyrLys: 1.044 ± 0.014	2.644TyrLeu: 2.644 ± 0.022	0.502TyrMet: 0.502 ± 0.009	1.044TyrAsn: 1.044 ± 0.015	1.513TyrPro: 1.513 ± 0.018	1.088TyrGln: 1.088 ± 0.015	1.642TyrArg: 1.642 ± 0.016	1.948TyrSer: 1.948 ± 0.02	1.519TyrThr: 1.519 ± 0.014	1.644TyrVal: 1.644 ± 0.017	0.4TyrTrp: 0.4 ± 0.008	0.815TyrTyr: 0.815 ± 0.011	0.008TyrXaa: 0.008 ± 0.001
Xaa	0.032XaaAla: 0.032 ± 0.003	0.004XaaCys: 0.004 ± 0.001	0.023XaaAsp: 0.023 ± 0.002	0.024XaaGlu: 0.024 ± 0.002	0.015XaaPhe: 0.015 ± 0.002	0.026XaaGly: 0.026 ± 0.002	0.01XaaHis: 0.01 ± 0.001	0.018XaaIle: 0.018 ± 0.002	0.02XaaLys: 0.02 ± 0.002	0.036XaaLeu: 0.036 ± 0.003	0.007XaaMet: 0.007 ± 0.001	0.013XaaAsn: 0.013 ± 0.001	0.031XaaPro: 0.031 ± 0.002	0.015XaaGln: 0.015 ± 0.002	0.027XaaArg: 0.027 ± 0.002	0.035XaaSer: 0.035 ± 0.003	0.021XaaThr: 0.021 ± 0.002	0.022XaaVal: 0.022 ± 0.002	0.006XaaTrp: 0.006 ± 0.001	0.009XaaTyr: 0.009 ± 0.001	0.036XaaXaa: 0.036 ± 0.004

Statistics based on 14686 proteins (6965245 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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