Amino acid dipepetide frequency for Hubei odonate virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.175AlaAla: 3.175 ± 0.59
0.489AlaCys: 0.489 ± 0.284
2.443AlaAsp: 2.443 ± 1.659
3.42AlaGlu: 3.42 ± 0.602
1.954AlaPhe: 1.954 ± 0.724
2.931AlaGly: 2.931 ± 0.627
1.466AlaHis: 1.466 ± 0.592
3.175AlaIle: 3.175 ± 1.731
3.42AlaLys: 3.42 ± 0.81
3.908AlaLeu: 3.908 ± 0.819
0.733AlaMet: 0.733 ± 0.526
2.198AlaAsn: 2.198 ± 0.84
1.71AlaPro: 1.71 ± 0.769
1.954AlaGln: 1.954 ± 0.726
2.931AlaArg: 2.931 ± 0.758
3.175AlaSer: 3.175 ± 0.576
1.71AlaThr: 1.71 ± 0.666
2.931AlaVal: 2.931 ± 1.016
0.489AlaTrp: 0.489 ± 0.258
0.733AlaTyr: 0.733 ± 0.314
0.0AlaXaa: 0.0 ± 0.0
Cys
1.221CysAla: 1.221 ± 0.465
0.244CysCys: 0.244 ± 0.142
0.244CysAsp: 0.244 ± 0.142
1.954CysGlu: 1.954 ± 0.99
0.244CysPhe: 0.244 ± 0.142
0.489CysGly: 0.489 ± 0.413
0.733CysHis: 0.733 ± 0.306
0.977CysIle: 0.977 ± 0.37
1.71CysLys: 1.71 ± 0.372
1.466CysLeu: 1.466 ± 0.371
0.0CysMet: 0.0 ± 0.0
0.244CysAsn: 0.244 ± 0.467
0.244CysPro: 0.244 ± 0.142
0.977CysGln: 0.977 ± 0.317
1.221CysArg: 1.221 ± 0.539
1.71CysSer: 1.71 ± 0.466
1.71CysThr: 1.71 ± 0.593
1.466CysVal: 1.466 ± 0.654
0.0CysTrp: 0.0 ± 0.0
0.733CysTyr: 0.733 ± 0.427
0.0CysXaa: 0.0 ± 0.0
Asp
1.954AspAla: 1.954 ± 1.087
0.977AspCys: 0.977 ± 0.371
2.931AspAsp: 2.931 ± 1.084
3.908AspGlu: 3.908 ± 1.158
2.687AspPhe: 2.687 ± 0.785
1.954AspGly: 1.954 ± 0.377
0.733AspHis: 0.733 ± 0.515
5.862AspIle: 5.862 ± 0.937
4.641AspLys: 4.641 ± 1.166
7.084AspLeu: 7.084 ± 1.198
0.977AspMet: 0.977 ± 0.969
1.954AspAsn: 1.954 ± 0.536
2.198AspPro: 2.198 ± 0.616
0.489AspGln: 0.489 ± 0.474
1.466AspArg: 1.466 ± 0.678
5.618AspSer: 5.618 ± 1.546
1.954AspThr: 1.954 ± 0.742
2.198AspVal: 2.198 ± 0.71
0.733AspTrp: 0.733 ± 0.427
0.733AspTyr: 0.733 ± 0.302
0.0AspXaa: 0.0 ± 0.0
Glu
4.397GluAla: 4.397 ± 1.686
0.977GluCys: 0.977 ± 0.395
3.42GluAsp: 3.42 ± 1.021
4.152GluGlu: 4.152 ± 0.832
1.954GluPhe: 1.954 ± 0.485
3.42GluGly: 3.42 ± 0.474
1.466GluHis: 1.466 ± 0.778
5.374GluIle: 5.374 ± 1.827
2.198GluLys: 2.198 ± 0.636
6.351GluLeu: 6.351 ± 0.867
2.198GluMet: 2.198 ± 0.354
3.908GluAsn: 3.908 ± 1.56
2.687GluPro: 2.687 ± 0.504
1.466GluGln: 1.466 ± 0.915
2.931GluArg: 2.931 ± 1.017
5.129GluSer: 5.129 ± 1.288
2.443GluThr: 2.443 ± 0.675
4.152GluVal: 4.152 ± 1.06
0.977GluTrp: 0.977 ± 0.498
1.954GluTyr: 1.954 ± 0.683
0.0GluXaa: 0.0 ± 0.0
Phe
1.71PheAla: 1.71 ± 0.466
1.221PheCys: 1.221 ± 0.526
1.221PheAsp: 1.221 ± 0.538
2.443PheGlu: 2.443 ± 0.853
1.954PhePhe: 1.954 ± 0.686
2.931PheGly: 2.931 ± 0.731
1.466PheHis: 1.466 ± 0.52
2.198PheIle: 2.198 ± 1.076
1.221PheLys: 1.221 ± 0.483
5.618PheLeu: 5.618 ± 1.277
0.489PheMet: 0.489 ± 0.413
1.221PheAsn: 1.221 ± 1.079
1.466PhePro: 1.466 ± 0.612
2.931PheGln: 2.931 ± 0.996
2.198PheArg: 2.198 ± 0.813
4.397PheSer: 4.397 ± 1.413
2.687PheThr: 2.687 ± 0.785
2.443PheVal: 2.443 ± 0.774
0.489PheTrp: 0.489 ± 0.433
1.71PheTyr: 1.71 ± 0.941
0.0PheXaa: 0.0 ± 0.0
Gly
1.954GlyAla: 1.954 ± 0.507
1.954GlyCys: 1.954 ± 0.745
2.931GlyAsp: 2.931 ± 1.351
3.908GlyGlu: 3.908 ± 0.758
2.198GlyPhe: 2.198 ± 0.425
2.687GlyGly: 2.687 ± 0.786
1.466GlyHis: 1.466 ± 0.592
3.175GlyIle: 3.175 ± 1.082
2.443GlyLys: 2.443 ± 0.538
5.618GlyLeu: 5.618 ± 1.704
1.954GlyMet: 1.954 ± 0.71
1.466GlyAsn: 1.466 ± 0.603
0.977GlyPro: 0.977 ± 0.556
0.733GlyGln: 0.733 ± 0.445
1.71GlyArg: 1.71 ± 0.558
4.641GlySer: 4.641 ± 0.627
2.198GlyThr: 2.198 ± 0.743
3.664GlyVal: 3.664 ± 0.676
1.221GlyTrp: 1.221 ± 0.483
0.977GlyTyr: 0.977 ± 0.305
0.0GlyXaa: 0.0 ± 0.0
His
1.221HisAla: 1.221 ± 0.711
0.244HisCys: 0.244 ± 0.142
1.71HisAsp: 1.71 ± 0.458
0.733HisGlu: 0.733 ± 0.477
0.977HisPhe: 0.977 ± 0.617
1.466HisGly: 1.466 ± 0.773
0.977HisHis: 0.977 ± 0.395
1.954HisIle: 1.954 ± 0.833
1.954HisLys: 1.954 ± 0.495
4.641HisLeu: 4.641 ± 0.832
0.489HisMet: 0.489 ± 0.433
1.221HisAsn: 1.221 ± 0.886
1.221HisPro: 1.221 ± 0.465
2.687HisGln: 2.687 ± 1.027
0.733HisArg: 0.733 ± 0.427
3.175HisSer: 3.175 ± 1.003
1.71HisThr: 1.71 ± 0.522
1.71HisVal: 1.71 ± 0.688
0.244HisTrp: 0.244 ± 0.142
2.443HisTyr: 2.443 ± 0.741
0.0HisXaa: 0.0 ± 0.0
Ile
4.397IleAla: 4.397 ± 0.915
0.733IleCys: 0.733 ± 0.427
2.931IleAsp: 2.931 ± 1.128
5.129IleGlu: 5.129 ± 1.226
4.152IlePhe: 4.152 ± 1.274
3.175IleGly: 3.175 ± 0.798
2.687IleHis: 2.687 ± 1.185
4.152IleIle: 4.152 ± 1.576
3.908IleLys: 3.908 ± 1.166
9.038IleLeu: 9.038 ± 1.82
1.71IleMet: 1.71 ± 0.655
2.687IleAsn: 2.687 ± 0.718
4.641IlePro: 4.641 ± 1.4
5.618IleGln: 5.618 ± 0.665
4.641IleArg: 4.641 ± 0.776
7.328IleSer: 7.328 ± 1.412
4.397IleThr: 4.397 ± 1.221
2.443IleVal: 2.443 ± 0.82
0.244IleTrp: 0.244 ± 0.142
2.443IleTyr: 2.443 ± 0.538
0.0IleXaa: 0.0 ± 0.0
Lys
2.687LysAla: 2.687 ± 1.004
0.489LysCys: 0.489 ± 0.284
3.175LysAsp: 3.175 ± 0.836
3.175LysGlu: 3.175 ± 1.092
1.954LysPhe: 1.954 ± 0.604
3.175LysGly: 3.175 ± 1.003
1.466LysHis: 1.466 ± 0.422
5.618LysIle: 5.618 ± 1.673
3.908LysLys: 3.908 ± 0.973
7.328LysLeu: 7.328 ± 1.694
0.977LysMet: 0.977 ± 0.395
3.908LysAsn: 3.908 ± 0.97
1.221LysPro: 1.221 ± 0.886
1.221LysGln: 1.221 ± 0.815
5.862LysArg: 5.862 ± 0.49
4.641LysSer: 4.641 ± 0.39
3.664LysThr: 3.664 ± 1.521
4.152LysVal: 4.152 ± 1.052
0.977LysTrp: 0.977 ± 0.371
1.71LysTyr: 1.71 ± 0.563
0.0LysXaa: 0.0 ± 0.0
Leu
4.885LeuAla: 4.885 ± 1.004
1.466LeuCys: 1.466 ± 1.517
5.862LeuAsp: 5.862 ± 1.85
4.641LeuGlu: 4.641 ± 1.046
2.687LeuPhe: 2.687 ± 0.811
5.129LeuGly: 5.129 ± 0.925
2.931LeuHis: 2.931 ± 0.613
7.816LeuIle: 7.816 ± 2.134
6.351LeuLys: 6.351 ± 0.631
10.747LeuLeu: 10.747 ± 2.407
3.908LeuMet: 3.908 ± 1.419
8.793LeuAsn: 8.793 ± 1.303
3.42LeuPro: 3.42 ± 0.96
4.885LeuGln: 4.885 ± 0.895
4.152LeuArg: 4.152 ± 0.614
13.19LeuSer: 13.19 ± 1.379
7.328LeuThr: 7.328 ± 1.908
3.664LeuVal: 3.664 ± 1.685
0.977LeuTrp: 0.977 ± 0.395
6.106LeuTyr: 6.106 ± 1.21
0.0LeuXaa: 0.0 ± 0.0
Met
0.977MetAla: 0.977 ± 0.498
0.489MetCys: 0.489 ± 0.433
0.244MetAsp: 0.244 ± 0.142
2.198MetGlu: 2.198 ± 0.721
0.244MetPhe: 0.244 ± 0.142
1.221MetGly: 1.221 ± 0.711
0.977MetHis: 0.977 ± 0.371
2.443MetIle: 2.443 ± 0.551
1.71MetLys: 1.71 ± 0.885
1.466MetLeu: 1.466 ± 0.531
0.977MetMet: 0.977 ± 0.311
1.221MetAsn: 1.221 ± 0.568
1.466MetPro: 1.466 ± 0.791
0.0MetGln: 0.0 ± 0.0
0.977MetArg: 0.977 ± 0.486
3.175MetSer: 3.175 ± 0.748
1.71MetThr: 1.71 ± 1.026
0.733MetVal: 0.733 ± 0.302
0.0MetTrp: 0.0 ± 0.0
0.733MetTyr: 0.733 ± 0.427
0.0MetXaa: 0.0 ± 0.0
Asn
1.466AsnAla: 1.466 ± 0.189
0.977AsnCys: 0.977 ± 0.741
2.198AsnAsp: 2.198 ± 0.42
2.931AsnGlu: 2.931 ± 0.506
3.175AsnPhe: 3.175 ± 0.522
0.489AsnGly: 0.489 ± 0.284
3.42AsnHis: 3.42 ± 1.517
4.152AsnIle: 4.152 ± 1.354
2.931AsnLys: 2.931 ± 0.801
3.664AsnLeu: 3.664 ± 0.45
0.733AsnMet: 0.733 ± 0.483
1.71AsnAsn: 1.71 ± 0.558
3.175AsnPro: 3.175 ± 1.068
1.71AsnGln: 1.71 ± 0.582
2.687AsnArg: 2.687 ± 0.337
4.641AsnSer: 4.641 ± 0.884
2.443AsnThr: 2.443 ± 0.583
2.687AsnVal: 2.687 ± 1.225
0.977AsnTrp: 0.977 ± 0.464
3.175AsnTyr: 3.175 ± 0.482
0.0AsnXaa: 0.0 ± 0.0
Pro
1.71ProAla: 1.71 ± 0.432
0.733ProCys: 0.733 ± 0.53
3.175ProAsp: 3.175 ± 0.835
3.175ProGlu: 3.175 ± 0.942
1.466ProPhe: 1.466 ± 0.412
1.71ProGly: 1.71 ± 0.716
0.977ProHis: 0.977 ± 0.372
3.175ProIle: 3.175 ± 0.94
1.466ProLys: 1.466 ± 0.577
3.175ProLeu: 3.175 ± 0.789
0.0ProMet: 0.0 ± 0.0
1.954ProAsn: 1.954 ± 1.193
2.198ProPro: 2.198 ± 0.42
1.71ProGln: 1.71 ± 0.432
1.71ProArg: 1.71 ± 1.044
4.641ProSer: 4.641 ± 0.983
2.931ProThr: 2.931 ± 1.083
2.687ProVal: 2.687 ± 0.906
0.977ProTrp: 0.977 ± 0.395
1.221ProTyr: 1.221 ± 0.511
0.0ProXaa: 0.0 ± 0.0
Gln
1.954GlnAla: 1.954 ± 1.06
0.489GlnCys: 0.489 ± 0.263
3.42GlnAsp: 3.42 ± 0.986
3.175GlnGlu: 3.175 ± 1.114
1.221GlnPhe: 1.221 ± 0.533
1.71GlnGly: 1.71 ± 0.432
1.466GlnHis: 1.466 ± 0.758
4.152GlnIle: 4.152 ± 1.455
4.885GlnLys: 4.885 ± 1.18
1.466GlnLeu: 1.466 ± 0.546
1.466GlnMet: 1.466 ± 0.57
0.977GlnAsn: 0.977 ± 0.317
0.977GlnPro: 0.977 ± 0.259
1.954GlnGln: 1.954 ± 0.286
1.221GlnArg: 1.221 ± 0.473
3.908GlnSer: 3.908 ± 1.038
2.198GlnThr: 2.198 ± 0.705
2.443GlnVal: 2.443 ± 1.133
0.0GlnTrp: 0.0 ± 0.0
1.466GlnTyr: 1.466 ± 0.769
0.0GlnXaa: 0.0 ± 0.0
Arg
2.443ArgAla: 2.443 ± 0.934
0.977ArgCys: 0.977 ± 0.542
3.908ArgAsp: 3.908 ± 1.175
2.443ArgGlu: 2.443 ± 0.623
2.443ArgPhe: 2.443 ± 0.697
2.198ArgGly: 2.198 ± 0.497
1.466ArgHis: 1.466 ± 0.354
3.664ArgIle: 3.664 ± 0.988
3.175ArgLys: 3.175 ± 0.956
4.885ArgLeu: 4.885 ± 1.038
1.221ArgMet: 1.221 ± 0.568
0.977ArgAsn: 0.977 ± 0.317
1.466ArgPro: 1.466 ± 0.371
2.687ArgGln: 2.687 ± 0.53
2.198ArgArg: 2.198 ± 0.835
3.42ArgSer: 3.42 ± 0.74
3.664ArgThr: 3.664 ± 1.081
3.42ArgVal: 3.42 ± 1.307
0.489ArgTrp: 0.489 ± 0.263
1.466ArgTyr: 1.466 ± 0.534
0.0ArgXaa: 0.0 ± 0.0
Ser
2.931SerAla: 2.931 ± 1.372
1.221SerCys: 1.221 ± 0.517
4.641SerAsp: 4.641 ± 0.782
5.129SerGlu: 5.129 ± 1.777
4.397SerPhe: 4.397 ± 0.479
5.374SerGly: 5.374 ± 0.599
2.443SerHis: 2.443 ± 0.961
7.816SerIle: 7.816 ± 1.0
6.106SerLys: 6.106 ± 1.186
13.679SerLeu: 13.679 ± 2.128
1.71SerMet: 1.71 ± 0.461
4.885SerAsn: 4.885 ± 1.554
3.664SerPro: 3.664 ± 0.811
2.443SerGln: 2.443 ± 0.741
4.641SerArg: 4.641 ± 0.737
8.305SerSer: 8.305 ± 0.389
6.106SerThr: 6.106 ± 1.185
4.641SerVal: 4.641 ± 0.882
1.954SerTrp: 1.954 ± 0.851
2.443SerTyr: 2.443 ± 0.99
0.0SerXaa: 0.0 ± 0.0
Thr
1.954ThrAla: 1.954 ± 0.606
1.71ThrCys: 1.71 ± 0.771
1.466ThrAsp: 1.466 ± 0.754
2.198ThrGlu: 2.198 ± 1.009
1.954ThrPhe: 1.954 ± 0.528
2.687ThrGly: 2.687 ± 0.787
1.954ThrHis: 1.954 ± 0.528
3.664ThrIle: 3.664 ± 0.45
2.931ThrLys: 2.931 ± 0.61
6.351ThrLeu: 6.351 ± 0.84
1.71ThrMet: 1.71 ± 0.606
3.175ThrAsn: 3.175 ± 1.011
2.931ThrPro: 2.931 ± 0.924
2.687ThrGln: 2.687 ± 0.928
3.175ThrArg: 3.175 ± 1.033
4.641ThrSer: 4.641 ± 1.673
4.641ThrThr: 4.641 ± 1.583
4.152ThrVal: 4.152 ± 0.717
1.71ThrTrp: 1.71 ± 0.196
1.954ThrTyr: 1.954 ± 0.607
0.0ThrXaa: 0.0 ± 0.0
Val
2.443ValAla: 2.443 ± 0.675
1.221ValCys: 1.221 ± 0.498
3.175ValAsp: 3.175 ± 0.73
3.42ValGlu: 3.42 ± 0.99
2.198ValPhe: 2.198 ± 0.851
3.664ValGly: 3.664 ± 0.961
1.954ValHis: 1.954 ± 1.031
3.42ValIle: 3.42 ± 0.648
3.175ValLys: 3.175 ± 0.767
7.084ValLeu: 7.084 ± 1.001
0.489ValMet: 0.489 ± 0.284
2.931ValAsn: 2.931 ± 1.601
2.687ValPro: 2.687 ± 0.785
1.954ValGln: 1.954 ± 0.964
1.71ValArg: 1.71 ± 0.682
5.862ValSer: 5.862 ± 1.007
2.198ValThr: 2.198 ± 0.645
2.687ValVal: 2.687 ± 0.601
0.244ValTrp: 0.244 ± 0.142
1.954ValTyr: 1.954 ± 0.495
0.0ValXaa: 0.0 ± 0.0
Trp
0.733TrpAla: 0.733 ± 0.302
0.0TrpCys: 0.0 ± 0.0
0.244TrpAsp: 0.244 ± 0.142
1.466TrpGlu: 1.466 ± 0.49
1.71TrpPhe: 1.71 ± 0.466
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.221TrpIle: 1.221 ± 0.473
1.221TrpLys: 1.221 ± 0.711
0.977TrpLeu: 0.977 ± 0.435
0.244TrpMet: 0.244 ± 0.142
0.489TrpAsn: 0.489 ± 0.284
0.489TrpPro: 0.489 ± 0.258
0.0TrpGln: 0.0 ± 0.0
0.489TrpArg: 0.489 ± 0.551
1.221TrpSer: 1.221 ± 0.483
0.977TrpThr: 0.977 ± 0.569
0.977TrpVal: 0.977 ± 0.395
0.0TrpTrp: 0.0 ± 0.0
0.489TrpTyr: 0.489 ± 0.284
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.733TyrAla: 0.733 ± 0.306
0.977TyrCys: 0.977 ± 0.372
1.71TyrAsp: 1.71 ± 0.636
1.954TyrGlu: 1.954 ± 0.792
2.443TyrPhe: 2.443 ± 0.965
1.466TyrGly: 1.466 ± 0.57
1.466TyrHis: 1.466 ± 0.534
2.443TyrIle: 2.443 ± 0.82
1.954TyrLys: 1.954 ± 1.138
4.397TyrLeu: 4.397 ± 1.11
0.733TyrMet: 0.733 ± 0.314
3.42TyrAsn: 3.42 ± 0.571
1.954TyrPro: 1.954 ± 0.71
2.443TyrGln: 2.443 ± 0.862
1.954TyrArg: 1.954 ± 0.581
1.954TyrSer: 1.954 ± 0.485
0.977TyrThr: 0.977 ± 0.693
1.221TyrVal: 1.221 ± 0.334
0.244TyrTrp: 0.244 ± 0.142
0.489TyrTyr: 0.489 ± 0.284
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4095 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski