Amino acid dipepetide frequency for Agromyces ramosus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.516AlaAla: 22.516 ± 0.241	0.645AlaCys: 0.645 ± 0.026	8.897AlaAsp: 8.897 ± 0.093	8.924AlaGlu: 8.924 ± 0.111	4.256AlaPhe: 4.256 ± 0.067	12.815AlaGly: 12.815 ± 0.119	2.465AlaHis: 2.465 ± 0.051	6.215AlaIle: 6.215 ± 0.084	2.466AlaLys: 2.466 ± 0.063	13.758AlaLeu: 13.758 ± 0.149	2.812AlaMet: 2.812 ± 0.054	2.332AlaAsn: 2.332 ± 0.048	7.051AlaPro: 7.051 ± 0.111	3.143AlaGln: 3.143 ± 0.057	9.922AlaArg: 9.922 ± 0.106	8.129AlaSer: 8.129 ± 0.084	7.803AlaThr: 7.803 ± 0.09	11.98AlaVal: 11.98 ± 0.136	2.113AlaTrp: 2.113 ± 0.047	2.447AlaTyr: 2.447 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.559CysAla: 0.559 ± 0.02	0.048CysCys: 0.048 ± 0.006	0.282CysAsp: 0.282 ± 0.016	0.243CysGlu: 0.243 ± 0.013	0.166CysPhe: 0.166 ± 0.015	0.492CysGly: 0.492 ± 0.025	0.111CysHis: 0.111 ± 0.012	0.185CysIle: 0.185 ± 0.012	0.052CysLys: 0.052 ± 0.007	0.422CysLeu: 0.422 ± 0.022	0.076CysMet: 0.076 ± 0.009	0.089CysAsn: 0.089 ± 0.01	0.29CysPro: 0.29 ± 0.016	0.095CysGln: 0.095 ± 0.008	0.335CysArg: 0.335 ± 0.017	0.297CysSer: 0.297 ± 0.018	0.304CysThr: 0.304 ± 0.015	0.374CysVal: 0.374 ± 0.018	0.076CysTrp: 0.076 ± 0.007	0.085CysTyr: 0.085 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	10.125AspAla: 10.125 ± 0.114	0.223AspCys: 0.223 ± 0.015	4.771AspAsp: 4.771 ± 0.081	4.949AspGlu: 4.949 ± 0.068	1.669AspPhe: 1.669 ± 0.044	6.368AspGly: 6.368 ± 0.092	1.245AspHis: 1.245 ± 0.041	1.996AspIle: 1.996 ± 0.045	0.695AspLys: 0.695 ± 0.031	6.328AspLeu: 6.328 ± 0.079	0.734AspMet: 0.734 ± 0.03	0.814AspAsn: 0.814 ± 0.033	4.446AspPro: 4.446 ± 0.06	1.396AspGln: 1.396 ± 0.033	5.152AspArg: 5.152 ± 0.087	2.373AspSer: 2.373 ± 0.039	2.734AspThr: 2.734 ± 0.055	5.662AspVal: 5.662 ± 0.089	0.992AspTrp: 0.992 ± 0.033	1.244AspTyr: 1.244 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	8.025GluAla: 8.025 ± 0.085	0.252GluCys: 0.252 ± 0.014	2.485GluAsp: 2.485 ± 0.054	3.212GluGlu: 3.212 ± 0.063	1.972GluPhe: 1.972 ± 0.047	4.209GluGly: 4.209 ± 0.07	1.691GluHis: 1.691 ± 0.044	2.529GluIle: 2.529 ± 0.056	0.992GluLys: 0.992 ± 0.033	7.734GluLeu: 7.734 ± 0.095	0.835GluMet: 0.835 ± 0.027	0.992GluAsn: 0.992 ± 0.031	3.68GluPro: 3.68 ± 0.07	2.234GluGln: 2.234 ± 0.048	6.222GluArg: 6.222 ± 0.088	2.957GluSer: 2.957 ± 0.051	2.897GluThr: 2.897 ± 0.049	5.04GluVal: 5.04 ± 0.071	1.055GluTrp: 1.055 ± 0.027	1.185GluTyr: 1.185 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.379PheAla: 4.379 ± 0.066	0.164PheCys: 0.164 ± 0.012	2.48PheAsp: 2.48 ± 0.047	2.002PheGlu: 2.002 ± 0.046	1.005PhePhe: 1.005 ± 0.034	3.526PheGly: 3.526 ± 0.063	0.59PheHis: 0.59 ± 0.024	1.234PheIle: 1.234 ± 0.034	0.378PheLys: 0.378 ± 0.018	2.858PheLeu: 2.858 ± 0.051	0.446PheMet: 0.446 ± 0.021	0.615PheAsn: 0.615 ± 0.023	1.411PhePro: 1.411 ± 0.036	0.717PheGln: 0.717 ± 0.028	2.009PheArg: 2.009 ± 0.042	1.583PheSer: 1.583 ± 0.038	2.029PheThr: 2.029 ± 0.048	2.82PheVal: 2.82 ± 0.055	0.512PheTrp: 0.512 ± 0.022	0.621PheTyr: 0.621 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	11.435GlyAla: 11.435 ± 0.117	0.541GlyCys: 0.541 ± 0.02	5.464GlyAsp: 5.464 ± 0.083	5.319GlyGlu: 5.319 ± 0.074	3.421GlyPhe: 3.421 ± 0.052	8.252GlyGly: 8.252 ± 0.143	1.856GlyHis: 1.856 ± 0.041	4.711GlyIle: 4.711 ± 0.063	1.654GlyLys: 1.654 ± 0.051	8.942GlyLeu: 8.942 ± 0.103	1.961GlyMet: 1.961 ± 0.039	1.614GlyAsn: 1.614 ± 0.044	4.088GlyPro: 4.088 ± 0.066	2.119GlyGln: 2.119 ± 0.048	7.054GlyArg: 7.054 ± 0.099	5.287GlySer: 5.287 ± 0.078	5.42GlyThr: 5.42 ± 0.077	8.148GlyVal: 8.148 ± 0.088	1.73GlyTrp: 1.73 ± 0.044	2.247GlyTyr: 2.247 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.564HisAla: 2.564 ± 0.05	0.094HisCys: 0.094 ± 0.01	1.458HisAsp: 1.458 ± 0.04	1.226HisGlu: 1.226 ± 0.034	0.578HisPhe: 0.578 ± 0.022	2.191HisGly: 2.191 ± 0.046	0.529HisHis: 0.529 ± 0.022	0.586HisIle: 0.586 ± 0.028	0.229HisLys: 0.229 ± 0.014	1.981HisLeu: 1.981 ± 0.044	0.273HisMet: 0.273 ± 0.016	0.307HisAsn: 0.307 ± 0.016	1.577HisPro: 1.577 ± 0.04	0.425HisGln: 0.425 ± 0.022	1.662HisArg: 1.662 ± 0.04	0.878HisSer: 0.878 ± 0.031	0.863HisThr: 0.863 ± 0.03	1.917HisVal: 1.917 ± 0.043	0.317HisTrp: 0.317 ± 0.017	0.433HisTyr: 0.433 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.968IleAla: 6.968 ± 0.09	0.209IleCys: 0.209 ± 0.014	3.372IleAsp: 3.372 ± 0.046	2.928IleGlu: 2.928 ± 0.054	1.056IlePhe: 1.056 ± 0.033	4.649IleGly: 4.649 ± 0.086	0.621IleHis: 0.621 ± 0.026	1.694IleIle: 1.694 ± 0.041	0.578IleLys: 0.578 ± 0.027	3.386IleLeu: 3.386 ± 0.058	0.571IleMet: 0.571 ± 0.024	0.703IleAsn: 0.703 ± 0.024	2.274IlePro: 2.274 ± 0.042	0.797IleGln: 0.797 ± 0.027	2.852IleArg: 2.852 ± 0.051	2.028IleSer: 2.028 ± 0.042	2.466IleThr: 2.466 ± 0.043	4.601IleVal: 4.601 ± 0.074	0.523IleTrp: 0.523 ± 0.022	0.677IleTyr: 0.677 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.006LysAla: 2.006 ± 0.048	0.049LysCys: 0.049 ± 0.007	0.817LysAsp: 0.817 ± 0.03	0.819LysGlu: 0.819 ± 0.032	0.388LysPhe: 0.388 ± 0.019	1.298LysGly: 1.298 ± 0.038	0.394LysHis: 0.394 ± 0.02	0.616LysIle: 0.616 ± 0.026	0.504LysLys: 0.504 ± 0.027	1.617LysLeu: 1.617 ± 0.048	0.28LysMet: 0.28 ± 0.017	0.368LysAsn: 0.368 ± 0.02	1.058LysPro: 1.058 ± 0.03	0.606LysGln: 0.606 ± 0.026	1.384LysArg: 1.384 ± 0.037	0.914LysSer: 0.914 ± 0.029	0.953LysThr: 0.953 ± 0.035	1.442LysVal: 1.442 ± 0.045	0.223LysTrp: 0.223 ± 0.013	0.347LysTyr: 0.347 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	15.675LeuAla: 15.675 ± 0.143	0.43LeuCys: 0.43 ± 0.021	7.15LeuAsp: 7.15 ± 0.094	5.952LeuGlu: 5.952 ± 0.083	2.808LeuPhe: 2.808 ± 0.058	9.616LeuGly: 9.616 ± 0.091	1.883LeuHis: 1.883 ± 0.042	4.078LeuIle: 4.078 ± 0.072	1.436LeuLys: 1.436 ± 0.038	10.103LeuLeu: 10.103 ± 0.133	1.473LeuMet: 1.473 ± 0.033	1.574LeuAsn: 1.574 ± 0.041	5.494LeuPro: 5.494 ± 0.068	2.264LeuGln: 2.264 ± 0.044	7.275LeuArg: 7.275 ± 0.093	5.103LeuSer: 5.103 ± 0.063	5.529LeuThr: 5.529 ± 0.064	10.203LeuVal: 10.203 ± 0.12	1.224LeuTrp: 1.224 ± 0.04	1.546LeuTyr: 1.546 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.054MetAla: 2.054 ± 0.045	0.087MetCys: 0.087 ± 0.009	0.767MetAsp: 0.767 ± 0.025	0.614MetGlu: 0.614 ± 0.024	0.486MetPhe: 0.486 ± 0.024	1.234MetGly: 1.234 ± 0.034	0.37MetHis: 0.37 ± 0.016	0.711MetIle: 0.711 ± 0.028	0.338MetLys: 0.338 ± 0.017	1.9MetLeu: 1.9 ± 0.042	0.265MetMet: 0.265 ± 0.019	0.446MetAsn: 0.446 ± 0.016	1.255MetPro: 1.255 ± 0.033	0.526MetGln: 0.526 ± 0.021	1.391MetArg: 1.391 ± 0.033	1.383MetSer: 1.383 ± 0.034	1.576MetThr: 1.576 ± 0.031	1.232MetVal: 1.232 ± 0.033	0.2MetTrp: 0.2 ± 0.014	0.261MetTyr: 0.261 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.292AsnAla: 2.292 ± 0.049	0.101AsnCys: 0.101 ± 0.009	1.085AsnAsp: 1.085 ± 0.03	0.927AsnGlu: 0.927 ± 0.031	0.577AsnPhe: 0.577 ± 0.021	1.782AsnGly: 1.782 ± 0.046	0.362AsnHis: 0.362 ± 0.017	0.691AsnIle: 0.691 ± 0.027	0.284AsnLys: 0.284 ± 0.017	1.75AsnLeu: 1.75 ± 0.041	0.263AsnMet: 0.263 ± 0.014	0.372AsnAsn: 0.372 ± 0.02	1.443AsnPro: 1.443 ± 0.04	0.493AsnGln: 0.493 ± 0.024	1.257AsnArg: 1.257 ± 0.037	0.856AsnSer: 0.856 ± 0.031	0.966AsnThr: 0.966 ± 0.032	1.547AsnVal: 1.547 ± 0.039	0.29AsnTrp: 0.29 ± 0.018	0.379AsnTyr: 0.379 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	7.762ProAla: 7.762 ± 0.105	0.162ProCys: 0.162 ± 0.014	4.311ProAsp: 4.311 ± 0.064	4.155ProGlu: 4.155 ± 0.075	1.785ProPhe: 1.785 ± 0.036	5.376ProGly: 5.376 ± 0.078	1.09ProHis: 1.09 ± 0.034	2.244ProIle: 2.244 ± 0.047	0.975ProLys: 0.975 ± 0.037	4.858ProLeu: 4.858 ± 0.072	0.949ProMet: 0.949 ± 0.028	1.05ProAsn: 1.05 ± 0.029	2.778ProPro: 2.778 ± 0.068	1.281ProGln: 1.281 ± 0.032	3.671ProArg: 3.671 ± 0.065	3.169ProSer: 3.169 ± 0.052	3.378ProThr: 3.378 ± 0.059	5.172ProVal: 5.172 ± 0.082	0.963ProTrp: 0.963 ± 0.031	1.03ProTyr: 1.03 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.284GlnAla: 3.284 ± 0.06	0.099GlnCys: 0.099 ± 0.009	1.039GlnAsp: 1.039 ± 0.034	1.206GlnGlu: 1.206 ± 0.034	0.813GlnPhe: 0.813 ± 0.028	1.899GlnGly: 1.899 ± 0.042	0.567GlnHis: 0.567 ± 0.023	0.989GlnIle: 0.989 ± 0.035	0.468GlnLys: 0.468 ± 0.023	2.918GlnLeu: 2.918 ± 0.057	0.394GlnMet: 0.394 ± 0.018	0.492GlnAsn: 0.492 ± 0.022	1.458GlnPro: 1.458 ± 0.036	1.005GlnGln: 1.005 ± 0.032	2.186GlnArg: 2.186 ± 0.048	1.261GlnSer: 1.261 ± 0.036	1.227GlnThr: 1.227 ± 0.029	2.279GlnVal: 2.279 ± 0.044	0.407GlnTrp: 0.407 ± 0.017	0.582GlnTyr: 0.582 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	9.778ArgAla: 9.778 ± 0.12	0.306ArgCys: 0.306 ± 0.017	4.54ArgAsp: 4.54 ± 0.069	4.664ArgGlu: 4.664 ± 0.073	2.602ArgPhe: 2.602 ± 0.048	5.757ArgGly: 5.757 ± 0.071	1.752ArgHis: 1.752 ± 0.042	3.782ArgIle: 3.782 ± 0.063	1.173ArgLys: 1.173 ± 0.032	8.089ArgLeu: 8.089 ± 0.1	1.832ArgMet: 1.832 ± 0.041	1.338ArgAsn: 1.338 ± 0.033	4.057ArgPro: 4.057 ± 0.064	1.908ArgGln: 1.908 ± 0.038	7.323ArgArg: 7.323 ± 0.105	4.206ArgSer: 4.206 ± 0.066	4.216ArgThr: 4.216 ± 0.06	6.463ArgVal: 6.463 ± 0.084	1.238ArgTrp: 1.238 ± 0.032	1.665ArgTyr: 1.665 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.911SerAla: 6.911 ± 0.073	0.257SerCys: 0.257 ± 0.014	3.038SerAsp: 3.038 ± 0.048	2.773SerGlu: 2.773 ± 0.05	1.764SerPhe: 1.764 ± 0.042	5.682SerGly: 5.682 ± 0.077	0.963SerHis: 0.963 ± 0.031	2.441SerIle: 2.441 ± 0.045	0.943SerLys: 0.943 ± 0.033	5.086SerLeu: 5.086 ± 0.066	1.054SerMet: 1.054 ± 0.027	0.974SerAsn: 0.974 ± 0.032	3.137SerPro: 3.137 ± 0.05	1.204SerGln: 1.204 ± 0.035	3.677SerArg: 3.677 ± 0.055	3.092SerSer: 3.092 ± 0.058	3.379SerThr: 3.379 ± 0.057	4.759SerVal: 4.759 ± 0.077	0.83SerTrp: 0.83 ± 0.026	1.109SerTyr: 1.109 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	7.481ThrAla: 7.481 ± 0.099	0.256ThrCys: 0.256 ± 0.013	3.52ThrAsp: 3.52 ± 0.058	3.013ThrGlu: 3.013 ± 0.054	1.795ThrPhe: 1.795 ± 0.039	5.628ThrGly: 5.628 ± 0.075	1.028ThrHis: 1.028 ± 0.032	2.718ThrIle: 2.718 ± 0.05	0.973ThrLys: 0.973 ± 0.031	5.462ThrLeu: 5.462 ± 0.077	0.957ThrMet: 0.957 ± 0.029	1.063ThrAsn: 1.063 ± 0.037	3.825ThrPro: 3.825 ± 0.062	1.238ThrGln: 1.238 ± 0.036	3.754ThrArg: 3.754 ± 0.05	3.109ThrSer: 3.109 ± 0.055	3.623ThrThr: 3.623 ± 0.059	5.316ThrVal: 5.316 ± 0.071	0.874ThrTrp: 0.874 ± 0.028	1.04ThrTyr: 1.04 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	12.802ValAla: 12.802 ± 0.147	0.443ValCys: 0.443 ± 0.018	6.246ValAsp: 6.246 ± 0.076	5.452ValGlu: 5.452 ± 0.078	2.91ValPhe: 2.91 ± 0.055	7.542ValGly: 7.542 ± 0.09	1.844ValHis: 1.844 ± 0.04	4.212ValIle: 4.212 ± 0.077	1.412ValLys: 1.412 ± 0.041	9.648ValLeu: 9.648 ± 0.103	1.341ValMet: 1.341 ± 0.037	1.749ValAsn: 1.749 ± 0.041	5.098ValPro: 5.098 ± 0.069	2.127ValGln: 2.127 ± 0.044	6.483ValArg: 6.483 ± 0.077	4.518ValSer: 4.518 ± 0.063	5.291ValThr: 5.291 ± 0.075	9.537ValVal: 9.537 ± 0.12	1.131ValTrp: 1.131 ± 0.03	1.55ValTyr: 1.55 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.683TrpAla: 1.683 ± 0.039	0.094TrpCys: 0.094 ± 0.008	0.824TrpAsp: 0.824 ± 0.031	0.649TrpGlu: 0.649 ± 0.024	0.619TrpPhe: 0.619 ± 0.02	1.074TrpGly: 1.074 ± 0.034	0.37TrpHis: 0.37 ± 0.018	0.784TrpIle: 0.784 ± 0.03	0.272TrpLys: 0.272 ± 0.013	1.858TrpLeu: 1.858 ± 0.047	0.353TrpMet: 0.353 ± 0.017	0.428TrpAsn: 0.428 ± 0.021	0.777TrpPro: 0.777 ± 0.027	0.507TrpGln: 0.507 ± 0.021	1.327TrpArg: 1.327 ± 0.036	0.934TrpSer: 0.934 ± 0.027	0.929TrpThr: 0.929 ± 0.033	1.225TrpVal: 1.225 ± 0.034	0.424TrpTrp: 0.424 ± 0.022	0.345TrpTyr: 0.345 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.391TyrAla: 2.391 ± 0.051	0.12TyrCys: 0.12 ± 0.011	1.372TyrAsp: 1.372 ± 0.038	1.172TyrGlu: 1.172 ± 0.031	0.708TyrPhe: 0.708 ± 0.024	1.874TyrGly: 1.874 ± 0.042	0.356TyrHis: 0.356 ± 0.019	0.538TyrIle: 0.538 ± 0.022	0.266TyrLys: 0.266 ± 0.016	2.117TyrLeu: 2.117 ± 0.045	0.228TyrMet: 0.228 ± 0.013	0.397TyrAsn: 0.397 ± 0.021	0.962TyrPro: 0.962 ± 0.027	0.49TyrGln: 0.49 ± 0.021	1.752TyrArg: 1.752 ± 0.043	0.993TyrSer: 0.993 ± 0.031	1.087TyrThr: 1.087 ± 0.034	1.62TyrVal: 1.62 ± 0.035	0.352TyrTrp: 0.352 ± 0.017	0.456TyrTyr: 0.456 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3588 proteins (1163547 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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