Amino acid dipepetide frequency for Wenling sobemo-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.036AlaAla: 6.036 ± 3.311
0.0AlaCys: 0.0 ± 0.0
8.048AlaAsp: 8.048 ± 2.934
8.048AlaGlu: 8.048 ± 1.507
3.018AlaPhe: 3.018 ± 1.656
5.03AlaGly: 5.03 ± 1.279
1.006AlaHis: 1.006 ± 0.552
5.03AlaIle: 5.03 ± 3.163
4.024AlaLys: 4.024 ± 2.207
9.054AlaLeu: 9.054 ± 2.006
2.012AlaMet: 2.012 ± 1.104
4.024AlaAsn: 4.024 ± 0.727
1.006AlaPro: 1.006 ± 0.552
3.018AlaGln: 3.018 ± 1.656
7.042AlaArg: 7.042 ± 0.902
1.006AlaSer: 1.006 ± 0.552
2.012AlaThr: 2.012 ± 0.377
5.03AlaVal: 5.03 ± 1.682
1.006AlaTrp: 1.006 ± 0.929
1.006AlaTyr: 1.006 ± 0.552
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.006CysAsp: 1.006 ± 0.929
0.0CysGlu: 0.0 ± 0.0
2.012CysPhe: 2.012 ± 1.857
3.018CysGly: 3.018 ± 0.175
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
3.018CysLeu: 3.018 ± 1.305
1.006CysMet: 1.006 ± 0.929
0.0CysAsn: 0.0 ± 0.0
1.006CysPro: 1.006 ± 0.552
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.006CysSer: 1.006 ± 0.929
0.0CysThr: 0.0 ± 0.0
1.006CysVal: 1.006 ± 0.552
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
8.048AspAla: 8.048 ± 1.454
2.012AspCys: 2.012 ± 1.857
5.03AspAsp: 5.03 ± 1.682
1.006AspGlu: 1.006 ± 0.929
3.018AspPhe: 3.018 ± 0.175
6.036AspGly: 6.036 ± 0.35
1.006AspHis: 1.006 ± 0.552
1.006AspIle: 1.006 ± 0.929
2.012AspLys: 2.012 ± 1.857
7.042AspLeu: 7.042 ± 0.579
1.006AspMet: 1.006 ± 0.552
3.018AspAsn: 3.018 ± 0.175
5.03AspPro: 5.03 ± 1.279
2.012AspGln: 2.012 ± 1.104
3.018AspArg: 3.018 ± 0.175
1.006AspSer: 1.006 ± 0.929
3.018AspThr: 3.018 ± 1.305
8.048AspVal: 8.048 ± 1.454
2.012AspTrp: 2.012 ± 1.857
8.048AspTyr: 8.048 ± 2.934
0.0AspXaa: 0.0 ± 0.0
Glu
5.03GluAla: 5.03 ± 0.202
0.0GluCys: 0.0 ± 0.0
4.024GluAsp: 4.024 ± 0.727
6.036GluGlu: 6.036 ± 1.831
4.024GluPhe: 4.024 ± 0.754
2.012GluGly: 2.012 ± 1.857
1.006GluHis: 1.006 ± 0.552
2.012GluIle: 2.012 ± 0.377
1.006GluLys: 1.006 ± 0.929
5.03GluLeu: 5.03 ± 1.682
3.018GluMet: 3.018 ± 1.656
2.012GluAsn: 2.012 ± 1.857
3.018GluPro: 3.018 ± 0.175
3.018GluGln: 3.018 ± 1.656
2.012GluArg: 2.012 ± 0.377
5.03GluSer: 5.03 ± 1.279
2.012GluThr: 2.012 ± 1.857
3.018GluVal: 3.018 ± 0.175
2.012GluTrp: 2.012 ± 1.104
2.012GluTyr: 2.012 ± 0.377
0.0GluXaa: 0.0 ± 0.0
Phe
4.024PheAla: 4.024 ± 0.727
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
5.03PheGlu: 5.03 ± 0.202
2.012PhePhe: 2.012 ± 1.857
5.03PheGly: 5.03 ± 1.682
0.0PheHis: 0.0 ± 0.0
3.018PheIle: 3.018 ± 1.305
2.012PheLys: 2.012 ± 1.104
3.018PheLeu: 3.018 ± 1.305
1.006PheMet: 1.006 ± 0.552
4.024PheAsn: 4.024 ± 3.715
0.0PhePro: 0.0 ± 0.0
2.012PheGln: 2.012 ± 0.377
5.03PheArg: 5.03 ± 0.202
2.012PheSer: 2.012 ± 1.104
4.024PheThr: 4.024 ± 0.727
7.042PheVal: 7.042 ± 2.059
0.0PheTrp: 0.0 ± 0.0
2.012PheTyr: 2.012 ± 0.377
0.0PheXaa: 0.0 ± 0.0
Gly
5.03GlyAla: 5.03 ± 0.202
3.018GlyCys: 3.018 ± 0.175
3.018GlyAsp: 3.018 ± 0.175
3.018GlyGlu: 3.018 ± 1.305
6.036GlyPhe: 6.036 ± 1.831
8.048GlyGly: 8.048 ± 1.454
1.006GlyHis: 1.006 ± 0.552
6.036GlyIle: 6.036 ± 2.611
3.018GlyLys: 3.018 ± 1.656
5.03GlyLeu: 5.03 ± 0.202
4.024GlyMet: 4.024 ± 0.457
2.012GlyAsn: 2.012 ± 0.377
1.006GlyPro: 1.006 ± 0.552
1.006GlyGln: 1.006 ± 0.552
2.012GlyArg: 2.012 ± 1.104
4.024GlySer: 4.024 ± 0.754
2.012GlyThr: 2.012 ± 0.377
7.042GlyVal: 7.042 ± 0.579
2.012GlyTrp: 2.012 ± 1.857
6.036GlyTyr: 6.036 ± 1.13
0.0GlyXaa: 0.0 ± 0.0
His
1.006HisAla: 1.006 ± 0.552
0.0HisCys: 0.0 ± 0.0
3.018HisAsp: 3.018 ± 0.175
1.006HisGlu: 1.006 ± 0.552
0.0HisPhe: 0.0 ± 0.0
2.012HisGly: 2.012 ± 0.377
0.0HisHis: 0.0 ± 0.0
1.006HisIle: 1.006 ± 0.552
1.006HisLys: 1.006 ± 0.929
3.018HisLeu: 3.018 ± 0.175
1.006HisMet: 1.006 ± 0.552
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
2.012HisGln: 2.012 ± 1.104
1.006HisArg: 1.006 ± 0.552
0.0HisSer: 0.0 ± 0.0
1.006HisThr: 1.006 ± 0.552
4.024HisVal: 4.024 ± 0.754
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.012IleAla: 2.012 ± 1.104
0.0IleCys: 0.0 ± 0.0
2.012IleAsp: 2.012 ± 1.104
1.006IleGlu: 1.006 ± 0.929
1.006IlePhe: 1.006 ± 0.929
2.012IleGly: 2.012 ± 1.857
3.018IleHis: 3.018 ± 1.305
2.012IleIle: 2.012 ± 1.857
4.024IleLys: 4.024 ± 0.754
4.024IleLeu: 4.024 ± 2.234
2.012IleMet: 2.012 ± 0.377
2.012IleAsn: 2.012 ± 1.104
0.0IlePro: 0.0 ± 0.0
1.006IleGln: 1.006 ± 0.929
2.012IleArg: 2.012 ± 0.377
3.018IleSer: 3.018 ± 1.305
1.006IleThr: 1.006 ± 0.929
4.024IleVal: 4.024 ± 0.754
0.0IleTrp: 0.0 ± 0.0
1.006IleTyr: 1.006 ± 0.929
0.0IleXaa: 0.0 ± 0.0
Lys
4.024LysAla: 4.024 ± 0.727
1.006LysCys: 1.006 ± 0.929
9.054LysAsp: 9.054 ± 0.525
6.036LysGlu: 6.036 ± 0.35
1.006LysPhe: 1.006 ± 0.929
5.03LysGly: 5.03 ± 0.202
2.012LysHis: 2.012 ± 1.104
2.012LysIle: 2.012 ± 1.104
7.042LysLys: 7.042 ± 0.902
0.0LysLeu: 0.0 ± 0.0
2.012LysMet: 2.012 ± 0.907
3.018LysAsn: 3.018 ± 0.175
6.036LysPro: 6.036 ± 1.13
0.0LysGln: 0.0 ± 0.0
2.012LysArg: 2.012 ± 0.377
4.024LysSer: 4.024 ± 0.754
6.036LysThr: 6.036 ± 3.311
5.03LysVal: 5.03 ± 1.279
1.006LysTrp: 1.006 ± 0.929
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
10.06LeuAla: 10.06 ± 1.884
2.012LeuCys: 2.012 ± 1.104
8.048LeuAsp: 8.048 ± 1.507
2.012LeuGlu: 2.012 ± 1.104
5.03LeuPhe: 5.03 ± 3.163
4.024LeuGly: 4.024 ± 0.727
4.024LeuHis: 4.024 ± 0.727
1.006LeuIle: 1.006 ± 0.552
4.024LeuLys: 4.024 ± 0.727
9.054LeuLeu: 9.054 ± 2.436
4.024LeuMet: 4.024 ± 2.207
4.024LeuAsn: 4.024 ± 2.234
6.036LeuPro: 6.036 ± 1.13
4.024LeuGln: 4.024 ± 0.727
3.018LeuArg: 3.018 ± 0.175
4.024LeuSer: 4.024 ± 2.234
3.018LeuThr: 3.018 ± 1.305
10.06LeuVal: 10.06 ± 2.557
0.0LeuTrp: 0.0 ± 0.0
3.018LeuTyr: 3.018 ± 1.305
0.0LeuXaa: 0.0 ± 0.0
Met
2.012MetAla: 2.012 ± 1.104
0.0MetCys: 0.0 ± 0.0
2.012MetAsp: 2.012 ± 0.377
2.012MetGlu: 2.012 ± 1.104
4.024MetPhe: 4.024 ± 2.207
2.012MetGly: 2.012 ± 1.104
2.012MetHis: 2.012 ± 1.104
0.0MetIle: 0.0 ± 0.0
5.03MetLys: 5.03 ± 1.279
3.018MetLeu: 3.018 ± 0.175
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.006MetPro: 1.006 ± 0.552
0.0MetGln: 0.0 ± 0.0
9.054MetArg: 9.054 ± 2.006
2.012MetSer: 2.012 ± 0.377
0.0MetThr: 0.0 ± 0.0
3.018MetVal: 3.018 ± 0.175
0.0MetTrp: 0.0 ± 0.0
1.006MetTyr: 1.006 ± 0.929
0.0MetXaa: 0.0 ± 0.0
Asn
4.024AsnAla: 4.024 ± 0.727
1.006AsnCys: 1.006 ± 0.929
4.024AsnAsp: 4.024 ± 0.727
1.006AsnGlu: 1.006 ± 0.929
2.012AsnPhe: 2.012 ± 1.857
5.03AsnGly: 5.03 ± 0.202
1.006AsnHis: 1.006 ± 0.929
0.0AsnIle: 0.0 ± 0.0
1.006AsnLys: 1.006 ± 0.552
3.018AsnLeu: 3.018 ± 1.656
1.006AsnMet: 1.006 ± 0.552
3.018AsnAsn: 3.018 ± 0.175
3.018AsnPro: 3.018 ± 1.305
0.0AsnGln: 0.0 ± 0.0
3.018AsnArg: 3.018 ± 0.175
3.018AsnSer: 3.018 ± 1.305
3.018AsnThr: 3.018 ± 1.656
1.006AsnVal: 1.006 ± 0.552
1.006AsnTrp: 1.006 ± 0.552
1.006AsnTyr: 1.006 ± 0.552
0.0AsnXaa: 0.0 ± 0.0
Pro
2.012ProAla: 2.012 ± 0.377
0.0ProCys: 0.0 ± 0.0
1.006ProAsp: 1.006 ± 0.552
5.03ProGlu: 5.03 ± 0.202
2.012ProPhe: 2.012 ± 0.377
4.024ProGly: 4.024 ± 0.727
1.006ProHis: 1.006 ± 0.929
1.006ProIle: 1.006 ± 0.929
3.018ProLys: 3.018 ± 1.656
4.024ProLeu: 4.024 ± 0.754
1.006ProMet: 1.006 ± 0.929
1.006ProAsn: 1.006 ± 0.552
1.006ProPro: 1.006 ± 0.552
0.0ProGln: 0.0 ± 0.0
0.0ProArg: 0.0 ± 0.0
8.048ProSer: 8.048 ± 1.454
2.012ProThr: 2.012 ± 0.377
3.018ProVal: 3.018 ± 0.175
1.006ProTrp: 1.006 ± 0.929
2.012ProTyr: 2.012 ± 0.377
0.0ProXaa: 0.0 ± 0.0
Gln
2.012GlnAla: 2.012 ± 1.104
0.0GlnCys: 0.0 ± 0.0
3.018GlnAsp: 3.018 ± 0.175
2.012GlnGlu: 2.012 ± 0.377
0.0GlnPhe: 0.0 ± 0.0
2.012GlnGly: 2.012 ± 0.377
0.0GlnHis: 0.0 ± 0.0
2.012GlnIle: 2.012 ± 1.104
3.018GlnLys: 3.018 ± 1.656
4.024GlnLeu: 4.024 ± 0.727
3.018GlnMet: 3.018 ± 1.656
2.012GlnAsn: 2.012 ± 0.377
2.012GlnPro: 2.012 ± 1.104
2.012GlnGln: 2.012 ± 1.104
1.006GlnArg: 1.006 ± 0.552
0.0GlnSer: 0.0 ± 0.0
2.012GlnThr: 2.012 ± 1.104
3.018GlnVal: 3.018 ± 1.656
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.03ArgAla: 5.03 ± 2.759
0.0ArgCys: 0.0 ± 0.0
2.012ArgAsp: 2.012 ± 0.377
0.0ArgGlu: 0.0 ± 0.0
4.024ArgPhe: 4.024 ± 0.754
2.012ArgGly: 2.012 ± 0.377
0.0ArgHis: 0.0 ± 0.0
2.012ArgIle: 2.012 ± 1.857
5.03ArgLys: 5.03 ± 0.202
8.048ArgLeu: 8.048 ± 0.027
2.012ArgMet: 2.012 ± 0.377
2.012ArgAsn: 2.012 ± 1.104
6.036ArgPro: 6.036 ± 1.831
4.024ArgGln: 4.024 ± 0.727
2.012ArgArg: 2.012 ± 0.377
2.012ArgSer: 2.012 ± 0.377
3.018ArgThr: 3.018 ± 0.175
2.012ArgVal: 2.012 ± 0.377
0.0ArgTrp: 0.0 ± 0.0
1.006ArgTyr: 1.006 ± 0.552
0.0ArgXaa: 0.0 ± 0.0
Ser
1.006SerAla: 1.006 ± 0.552
2.012SerCys: 2.012 ± 1.857
1.006SerAsp: 1.006 ± 0.929
3.018SerGlu: 3.018 ± 1.305
3.018SerPhe: 3.018 ± 0.175
5.03SerGly: 5.03 ± 1.682
1.006SerHis: 1.006 ± 0.552
2.012SerIle: 2.012 ± 1.857
8.048SerLys: 8.048 ± 0.027
3.018SerLeu: 3.018 ± 0.175
2.012SerMet: 2.012 ± 1.104
2.012SerAsn: 2.012 ± 1.104
1.006SerPro: 1.006 ± 0.929
1.006SerGln: 1.006 ± 0.552
3.018SerArg: 3.018 ± 0.175
5.03SerSer: 5.03 ± 3.163
5.03SerThr: 5.03 ± 0.202
2.012SerVal: 2.012 ± 1.104
1.006SerTrp: 1.006 ± 0.929
1.006SerTyr: 1.006 ± 0.552
0.0SerXaa: 0.0 ± 0.0
Thr
4.024ThrAla: 4.024 ± 0.754
1.006ThrCys: 1.006 ± 0.929
3.018ThrAsp: 3.018 ± 1.305
0.0ThrGlu: 0.0 ± 0.0
2.012ThrPhe: 2.012 ± 0.377
3.018ThrGly: 3.018 ± 0.175
1.006ThrHis: 1.006 ± 0.552
3.018ThrIle: 3.018 ± 2.786
1.006ThrLys: 1.006 ± 0.929
5.03ThrLeu: 5.03 ± 3.163
0.0ThrMet: 0.0 ± 0.0
3.018ThrAsn: 3.018 ± 1.656
2.012ThrPro: 2.012 ± 0.377
4.024ThrGln: 4.024 ± 2.207
2.012ThrArg: 2.012 ± 1.104
2.012ThrSer: 2.012 ± 1.104
2.012ThrThr: 2.012 ± 1.104
7.042ThrVal: 7.042 ± 0.902
1.006ThrTrp: 1.006 ± 0.929
2.012ThrTyr: 2.012 ± 1.104
0.0ThrXaa: 0.0 ± 0.0
Val
7.042ValAla: 7.042 ± 3.863
1.006ValCys: 1.006 ± 0.552
6.036ValAsp: 6.036 ± 1.13
8.048ValGlu: 8.048 ± 0.027
1.006ValPhe: 1.006 ± 0.552
9.054ValGly: 9.054 ± 0.525
0.0ValHis: 0.0 ± 0.0
4.024ValIle: 4.024 ± 2.207
11.066ValLys: 11.066 ± 0.148
8.048ValLeu: 8.048 ± 0.027
4.024ValMet: 4.024 ± 2.207
2.012ValAsn: 2.012 ± 1.104
1.006ValPro: 1.006 ± 0.929
4.024ValGln: 4.024 ± 0.727
2.012ValArg: 2.012 ± 0.377
4.024ValSer: 4.024 ± 0.754
4.024ValThr: 4.024 ± 3.715
8.048ValVal: 8.048 ± 2.934
0.0ValTrp: 0.0 ± 0.0
1.006ValTyr: 1.006 ± 0.552
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
3.018TrpAsp: 3.018 ± 1.305
0.0TrpGlu: 0.0 ± 0.0
2.012TrpPhe: 2.012 ± 1.857
0.0TrpGly: 0.0 ± 0.0
1.006TrpHis: 1.006 ± 0.929
0.0TrpIle: 0.0 ± 0.0
1.006TrpLys: 1.006 ± 0.929
2.012TrpLeu: 2.012 ± 1.104
1.006TrpMet: 1.006 ± 0.929
0.0TrpAsn: 0.0 ± 0.0
1.006TrpPro: 1.006 ± 0.929
0.0TrpGln: 0.0 ± 0.0
1.006TrpArg: 1.006 ± 0.929
0.0TrpSer: 0.0 ± 0.0
1.006TrpThr: 1.006 ± 0.929
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.024TyrAla: 4.024 ± 2.234
0.0TyrCys: 0.0 ± 0.0
4.024TyrAsp: 4.024 ± 0.727
3.018TyrGlu: 3.018 ± 1.656
4.024TyrPhe: 4.024 ± 0.754
1.006TyrGly: 1.006 ± 0.552
1.006TyrHis: 1.006 ± 0.552
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
2.012TyrLeu: 2.012 ± 1.104
2.012TyrMet: 2.012 ± 0.377
2.012TyrAsn: 2.012 ± 1.104
1.006TyrPro: 1.006 ± 0.929
0.0TyrGln: 0.0 ± 0.0
2.012TyrArg: 2.012 ± 1.857
1.006TyrSer: 1.006 ± 0.552
2.012TyrThr: 2.012 ± 1.104
2.012TyrVal: 2.012 ± 1.104
1.006TyrTrp: 1.006 ± 0.929
1.006TyrTyr: 1.006 ± 0.552
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (995 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski