Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) (Penicillium marneffei)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces; Talaromyces sect. Talaromyces; Talaromyces marneffei

Average proteome isoelectric point is 6.38

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10448 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|B6QJD3|B6QJD3_TALMQ Uncharacterized protein OS=Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) OX=441960 GN=PMAA_090770 PE=4 SV=1
MM1 pKa = 7.68IGFLDD6 pKa = 3.91LPGEE10 pKa = 4.17IRR12 pKa = 11.84NLIYY16 pKa = 10.27DD17 pKa = 4.18HH18 pKa = 7.37PLMFQEE24 pKa = 5.78PIVPWAKK31 pKa = 10.09EE32 pKa = 3.52QALPISLFYY41 pKa = 10.28TNKK44 pKa = 8.32TIYY47 pKa = 10.43RR48 pKa = 11.84EE49 pKa = 4.17FCSLFYY55 pKa = 11.14SRR57 pKa = 11.84ITFNFTSHH65 pKa = 6.28EE66 pKa = 4.27LGHH69 pKa = 6.5EE70 pKa = 4.12EE71 pKa = 4.17HH72 pKa = 6.31QCPARR77 pKa = 11.84LTKK80 pKa = 10.37QVTSFLDD87 pKa = 3.74QIGQNAKK94 pKa = 9.87YY95 pKa = 9.9IEE97 pKa = 4.6SIKK100 pKa = 10.49PDD102 pKa = 4.1FPPQEE107 pKa = 3.88IRR109 pKa = 11.84DD110 pKa = 4.03LGWEE114 pKa = 4.15VEE116 pKa = 4.54LVDD119 pKa = 4.96PLDD122 pKa = 4.21SQWMIDD128 pKa = 4.73DD129 pKa = 5.4DD130 pKa = 4.07EE131 pKa = 7.13HH132 pKa = 9.17DD133 pKa = 5.53DD134 pKa = 4.97DD135 pKa = 7.28DD136 pKa = 6.11EE137 pKa = 6.33DD138 pKa = 5.17VDD140 pKa = 5.21DD141 pKa = 6.29AKK143 pKa = 11.38DD144 pKa = 3.6DD145 pKa = 3.72YY146 pKa = 11.48DD147 pKa = 4.25YY148 pKa = 11.86YY149 pKa = 11.18EE150 pKa = 4.76SYY152 pKa = 11.31EE153 pKa = 4.07DD154 pKa = 5.51DD155 pKa = 3.89EE156 pKa = 5.86YY157 pKa = 11.84GDD159 pKa = 3.63EE160 pKa = 4.55DD161 pKa = 5.03DD162 pKa = 4.65YY163 pKa = 11.99YY164 pKa = 11.22DD165 pKa = 4.12YY166 pKa = 11.18EE167 pKa = 4.32SHH169 pKa = 7.1EE170 pKa = 4.96DD171 pKa = 3.9EE172 pKa = 5.96DD173 pKa = 6.45DD174 pKa = 3.59EE175 pKa = 7.26DD176 pKa = 4.84EE177 pKa = 5.85DD178 pKa = 5.58DD179 pKa = 4.73GSGDD183 pKa = 3.52GSDD186 pKa = 4.06GEE188 pKa = 4.47EE189 pKa = 3.83

Molecular weight: 22.27 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|B6QKP2|B6QKP2_TALMQ Endo-1 3(4)-beta-glucanase OS=Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) OX=441960 GN=PMAA_054650 PE=3 SV=1
MM1 pKa = 7.17PAKK4 pKa = 10.23GASTRR9 pKa = 11.84LNPVRR14 pKa = 11.84LQTIQHH20 pKa = 5.6LRR22 pKa = 11.84VRR24 pKa = 11.84RR25 pKa = 11.84PNQQQQNSCATIMSSMLNCWASAGQGNEE53 pKa = 3.91GCSGLEE59 pKa = 3.96EE60 pKa = 4.16SLKK63 pKa = 10.96ACMDD67 pKa = 3.31GRR69 pKa = 11.84RR70 pKa = 11.84DD71 pKa = 3.41TTSANNAVNYY81 pKa = 10.05HH82 pKa = 5.96LMRR85 pKa = 11.84MFPKK89 pKa = 10.4VSGPRR94 pKa = 11.84KK95 pKa = 9.27RR96 pKa = 11.84EE97 pKa = 3.63GRR99 pKa = 11.84LGG101 pKa = 3.44

Molecular weight: 11.16 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

10028

420

10448

5285136

44

10022

505.9

56.21

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.149 ± 0.022

1.161 ± 0.009

5.695 ± 0.02

6.228 ± 0.023

3.745 ± 0.013

6.499 ± 0.023

2.38 ± 0.01

5.438 ± 0.016

4.915 ± 0.022

8.947 ± 0.026

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.14 ± 0.009

3.998 ± 0.011

5.69 ± 0.023

4.149 ± 0.017

5.951 ± 0.019

8.357 ± 0.027

6.151 ± 0.016

6.053 ± 0.016

1.425 ± 0.008

2.929 ± 0.013
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski