Amino acid dipepetide frequency for Phlebiopsis gigantea mycovirus dsRNA 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.307AlaAla: 14.307 ± 3.335
0.876AlaCys: 0.876 ± 0.11
6.715AlaAsp: 6.715 ± 2.074
4.38AlaGlu: 4.38 ± 0.374
2.92AlaPhe: 2.92 ± 0.059
7.591AlaGly: 7.591 ± 1.722
3.212AlaHis: 3.212 ± 1.598
2.92AlaIle: 2.92 ± 0.403
2.92AlaLys: 2.92 ± 0.865
10.803AlaLeu: 10.803 ± 1.722
2.628AlaMet: 2.628 ± 0.792
3.796AlaAsn: 3.796 ± 1.554
6.131AlaPro: 6.131 ± 1.231
4.964AlaGln: 4.964 ± 0.469
8.467AlaArg: 8.467 ± 0.447
7.883AlaSer: 7.883 ± 0.066
4.38AlaThr: 4.38 ± 0.374
7.299AlaVal: 7.299 ± 0.315
0.876AlaTrp: 0.876 ± 0.572
3.796AlaTyr: 3.796 ± 0.63
0.292AlaXaa: 0.292 ± 0.191
Cys
0.876CysAla: 0.876 ± 0.814
0.0CysCys: 0.0 ± 0.0
0.876CysAsp: 0.876 ± 0.572
0.292CysGlu: 0.292 ± 0.271
0.0CysPhe: 0.0 ± 0.0
0.584CysGly: 0.584 ± 0.081
0.584CysHis: 0.584 ± 0.081
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.876CysLeu: 0.876 ± 0.11
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.752CysPro: 1.752 ± 0.22
0.292CysGln: 0.292 ± 0.191
0.876CysArg: 0.876 ± 0.11
0.292CysSer: 0.292 ± 0.191
0.876CysThr: 0.876 ± 0.572
0.584CysVal: 0.584 ± 0.381
0.292CysTrp: 0.292 ± 0.191
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.839AspAla: 5.839 ± 0.344
0.0AspCys: 0.0 ± 0.0
2.044AspAsp: 2.044 ± 0.975
2.628AspGlu: 2.628 ± 0.132
2.92AspPhe: 2.92 ± 0.52
5.255AspGly: 5.255 ± 1.187
1.168AspHis: 1.168 ± 0.623
1.752AspIle: 1.752 ± 0.704
1.752AspLys: 1.752 ± 1.165
9.051AspLeu: 9.051 ± 0.095
1.168AspMet: 1.168 ± 0.623
1.46AspAsn: 1.46 ± 0.491
3.796AspPro: 3.796 ± 0.169
1.752AspGln: 1.752 ± 0.242
2.628AspArg: 2.628 ± 0.132
2.044AspSer: 2.044 ± 0.872
3.796AspThr: 3.796 ± 1.092
5.255AspVal: 5.255 ± 0.198
2.628AspTrp: 2.628 ± 0.33
3.504AspTyr: 3.504 ± 1.407
0.0AspXaa: 0.0 ± 0.0
Glu
1.752GluAla: 1.752 ± 0.242
0.292GluCys: 0.292 ± 0.191
2.044GluAsp: 2.044 ± 0.41
1.752GluGlu: 1.752 ± 0.242
2.92GluPhe: 2.92 ± 1.906
2.92GluGly: 2.92 ± 0.403
0.876GluHis: 0.876 ± 0.352
2.336GluIle: 2.336 ± 0.322
1.752GluLys: 1.752 ± 0.22
3.504GluLeu: 3.504 ± 0.945
0.292GluMet: 0.292 ± 0.271
0.584GluAsn: 0.584 ± 0.542
2.044GluPro: 2.044 ± 0.513
0.876GluGln: 0.876 ± 0.11
3.796GluArg: 3.796 ± 0.755
2.628GluSer: 2.628 ± 0.594
2.628GluThr: 2.628 ± 0.594
4.38GluVal: 4.38 ± 0.55
0.876GluTrp: 0.876 ± 0.352
2.336GluTyr: 2.336 ± 0.784
0.0GluXaa: 0.0 ± 0.0
Phe
2.92PheAla: 2.92 ± 0.52
0.0PheCys: 0.0 ± 0.0
2.044PheAsp: 2.044 ± 0.41
0.876PheGlu: 0.876 ± 0.814
2.336PhePhe: 2.336 ± 1.063
3.796PheGly: 3.796 ± 1.554
0.292PheHis: 0.292 ± 0.191
0.584PheIle: 0.584 ± 0.081
1.46PheLys: 1.46 ± 0.432
4.38PheLeu: 4.38 ± 0.088
0.584PheMet: 0.584 ± 0.381
1.752PheAsn: 1.752 ± 0.704
2.336PhePro: 2.336 ± 0.601
1.168PheGln: 1.168 ± 0.301
1.752PheArg: 1.752 ± 0.682
2.336PheSer: 2.336 ± 1.063
2.92PheThr: 2.92 ± 0.059
3.796PheVal: 3.796 ± 0.169
0.292PheTrp: 0.292 ± 0.271
1.752PheTyr: 1.752 ± 0.22
0.0PheXaa: 0.0 ± 0.0
Gly
7.299GlyAla: 7.299 ± 1.532
0.292GlyCys: 0.292 ± 0.191
5.255GlyAsp: 5.255 ± 0.264
3.212GlyGlu: 3.212 ± 0.674
4.088GlyPhe: 4.088 ± 0.103
4.964GlyGly: 4.964 ± 1.393
1.752GlyHis: 1.752 ± 0.682
3.796GlyIle: 3.796 ± 0.755
3.212GlyLys: 3.212 ± 0.213
8.175GlyLeu: 8.175 ± 1.18
1.752GlyMet: 1.752 ± 0.704
2.336GlyAsn: 2.336 ± 1.063
5.547GlyPro: 5.547 ± 1.312
2.336GlyGln: 2.336 ± 0.322
4.964GlyArg: 4.964 ± 1.393
5.547GlySer: 5.547 ± 0.073
3.504GlyThr: 3.504 ± 0.44
5.547GlyVal: 5.547 ± 1.458
1.46GlyTrp: 1.46 ± 0.491
3.504GlyTyr: 3.504 ± 1.407
0.0GlyXaa: 0.0 ± 0.0
His
1.46HisAla: 1.46 ± 0.029
0.292HisCys: 0.292 ± 0.191
0.584HisAsp: 0.584 ± 0.081
0.584HisGlu: 0.584 ± 0.081
1.46HisPhe: 1.46 ± 0.491
2.044HisGly: 2.044 ± 0.975
1.168HisHis: 1.168 ± 0.161
0.876HisIle: 0.876 ± 0.352
1.752HisLys: 1.752 ± 0.242
2.336HisLeu: 2.336 ± 1.246
0.292HisMet: 0.292 ± 0.191
1.168HisAsn: 1.168 ± 0.161
1.168HisPro: 1.168 ± 0.161
0.876HisGln: 0.876 ± 0.352
1.168HisArg: 1.168 ± 0.301
2.336HisSer: 2.336 ± 0.601
1.46HisThr: 1.46 ± 0.432
1.46HisVal: 1.46 ± 0.432
0.0HisTrp: 0.0 ± 0.0
0.292HisTyr: 0.292 ± 0.191
0.0HisXaa: 0.0 ± 0.0
Ile
4.38IleAla: 4.38 ± 1.759
0.0IleCys: 0.0 ± 0.0
3.212IleAsp: 3.212 ± 0.213
1.752IleGlu: 1.752 ± 1.165
0.584IlePhe: 0.584 ± 0.081
2.92IleGly: 2.92 ± 0.403
0.876IleHis: 0.876 ± 0.352
0.876IleIle: 0.876 ± 0.11
2.044IleLys: 2.044 ± 0.513
2.336IleLeu: 2.336 ± 0.139
0.292IleMet: 0.292 ± 0.191
1.168IleAsn: 1.168 ± 0.623
2.044IlePro: 2.044 ± 0.975
0.876IleGln: 0.876 ± 0.814
2.628IleArg: 2.628 ± 0.594
1.168IleSer: 1.168 ± 0.161
1.46IleThr: 1.46 ± 0.029
2.336IleVal: 2.336 ± 0.139
0.584IleTrp: 0.584 ± 0.381
1.46IleTyr: 1.46 ± 0.029
0.0IleXaa: 0.0 ± 0.0
Lys
1.46LysAla: 1.46 ± 0.029
0.292LysCys: 0.292 ± 0.271
2.044LysAsp: 2.044 ± 0.513
1.752LysGlu: 1.752 ± 0.22
0.876LysPhe: 0.876 ± 0.11
2.044LysGly: 2.044 ± 0.975
0.292LysHis: 0.292 ± 0.271
0.584LysIle: 0.584 ± 0.081
2.044LysLys: 2.044 ± 0.051
2.92LysLeu: 2.92 ± 0.865
1.752LysMet: 1.752 ± 1.143
0.292LysAsn: 0.292 ± 0.271
0.584LysPro: 0.584 ± 0.081
0.584LysGln: 0.584 ± 0.542
4.088LysArg: 4.088 ± 2.411
2.044LysSer: 2.044 ± 0.051
2.336LysThr: 2.336 ± 0.784
2.044LysVal: 2.044 ± 0.975
1.168LysTrp: 1.168 ± 0.623
1.168LysTyr: 1.168 ± 0.161
0.0LysXaa: 0.0 ± 0.0
Leu
12.263LeuAla: 12.263 ± 1.077
0.876LeuCys: 0.876 ± 0.11
5.839LeuAsp: 5.839 ± 1.268
3.796LeuGlu: 3.796 ± 0.755
2.92LeuPhe: 2.92 ± 0.403
7.591LeuGly: 7.591 ± 0.799
2.044LeuHis: 2.044 ± 0.051
3.796LeuIle: 3.796 ± 1.217
3.796LeuLys: 3.796 ± 1.217
9.927LeuLeu: 9.927 ± 1.832
0.584LeuMet: 0.584 ± 0.081
3.212LeuAsn: 3.212 ± 0.249
6.423LeuPro: 6.423 ± 0.425
2.044LeuGln: 2.044 ± 0.513
7.591LeuArg: 7.591 ± 0.337
8.175LeuSer: 8.175 ± 1.642
4.964LeuThr: 4.964 ± 0.454
8.175LeuVal: 8.175 ± 0.718
2.044LeuTrp: 2.044 ± 0.051
4.672LeuTyr: 4.672 ± 2.492
0.0LeuXaa: 0.0 ± 0.0
Met
0.292MetAla: 0.292 ± 0.271
0.0MetCys: 0.0 ± 0.0
1.46MetAsp: 1.46 ± 0.029
0.0MetGlu: 0.0 ± 0.0
1.168MetPhe: 1.168 ± 0.161
1.46MetGly: 1.46 ± 0.953
0.876MetHis: 0.876 ± 0.572
1.168MetIle: 1.168 ± 1.085
0.292MetLys: 0.292 ± 0.271
0.584MetLeu: 0.584 ± 0.381
0.292MetMet: 0.292 ± 0.271
0.876MetAsn: 0.876 ± 0.352
0.876MetPro: 0.876 ± 0.572
1.46MetGln: 1.46 ± 0.491
1.752MetArg: 1.752 ± 0.682
1.46MetSer: 1.46 ± 0.029
0.0MetThr: 0.0 ± 0.0
1.168MetVal: 1.168 ± 0.762
0.292MetTrp: 0.292 ± 0.191
1.168MetTyr: 1.168 ± 1.085
0.0MetXaa: 0.0 ± 0.0
Asn
4.672AsnAla: 4.672 ± 0.183
0.0AsnCys: 0.0 ± 0.0
0.584AsnAsp: 0.584 ± 0.081
1.752AsnGlu: 1.752 ± 0.242
1.46AsnPhe: 1.46 ± 0.953
3.504AsnGly: 3.504 ± 0.902
0.292AsnHis: 0.292 ± 0.271
0.584AsnIle: 0.584 ± 0.381
0.876AsnLys: 0.876 ± 0.814
2.336AsnLeu: 2.336 ± 0.139
0.292AsnMet: 0.292 ± 0.191
0.876AsnAsn: 0.876 ± 0.11
3.504AsnPro: 3.504 ± 0.44
0.876AsnGln: 0.876 ± 0.352
1.752AsnArg: 1.752 ± 0.22
0.876AsnSer: 0.876 ± 0.11
0.584AsnThr: 0.584 ± 0.542
3.796AsnVal: 3.796 ± 1.092
0.876AsnTrp: 0.876 ± 0.572
1.168AsnTyr: 1.168 ± 0.161
0.0AsnXaa: 0.0 ± 0.0
Pro
7.883ProAla: 7.883 ± 0.989
0.584ProCys: 0.584 ± 0.381
3.796ProAsp: 3.796 ± 1.678
2.336ProGlu: 2.336 ± 0.601
1.168ProPhe: 1.168 ± 0.161
4.964ProGly: 4.964 ± 1.393
1.752ProHis: 1.752 ± 0.242
1.752ProIle: 1.752 ± 0.242
1.168ProLys: 1.168 ± 0.161
3.796ProLeu: 3.796 ± 0.169
0.292ProMet: 0.292 ± 0.191
3.212ProAsn: 3.212 ± 1.634
4.088ProPro: 4.088 ± 1.283
1.752ProGln: 1.752 ± 1.165
6.131ProArg: 6.131 ± 2.617
6.423ProSer: 6.423 ± 0.037
3.212ProThr: 3.212 ± 1.634
5.255ProVal: 5.255 ± 1.583
0.292ProTrp: 0.292 ± 0.191
2.044ProTyr: 2.044 ± 0.975
0.0ProXaa: 0.0 ± 0.0
Gln
4.964GlnAla: 4.964 ± 0.931
0.292GlnCys: 0.292 ± 0.191
2.628GlnAsp: 2.628 ± 0.594
0.876GlnGlu: 0.876 ± 0.572
0.876GlnPhe: 0.876 ± 0.814
3.212GlnGly: 3.212 ± 0.213
0.0GlnHis: 0.0 ± 0.0
1.752GlnIle: 1.752 ± 0.704
0.584GlnLys: 0.584 ± 0.081
5.839GlnLeu: 5.839 ± 1.73
0.292GlnMet: 0.292 ± 0.191
0.876GlnAsn: 0.876 ± 0.572
1.168GlnPro: 1.168 ± 0.762
0.584GlnGln: 0.584 ± 0.081
1.752GlnArg: 1.752 ± 0.242
0.876GlnSer: 0.876 ± 0.11
2.044GlnThr: 2.044 ± 0.975
1.752GlnVal: 1.752 ± 0.704
0.876GlnTrp: 0.876 ± 0.352
0.292GlnTyr: 0.292 ± 0.191
0.0GlnXaa: 0.0 ± 0.0
Arg
10.803ArgAla: 10.803 ± 0.586
1.168ArgCys: 1.168 ± 0.301
3.504ArgAsp: 3.504 ± 0.022
4.088ArgGlu: 4.088 ± 1.026
2.92ArgPhe: 2.92 ± 0.982
5.255ArgGly: 5.255 ± 0.264
2.336ArgHis: 2.336 ± 0.139
2.92ArgIle: 2.92 ± 0.403
2.044ArgLys: 2.044 ± 0.051
8.467ArgLeu: 8.467 ± 0.447
1.168ArgMet: 1.168 ± 0.161
2.044ArgAsn: 2.044 ± 0.051
3.796ArgPro: 3.796 ± 1.092
2.044ArgGln: 2.044 ± 0.41
8.759ArgArg: 8.759 ± 1.099
4.088ArgSer: 4.088 ± 0.564
4.672ArgThr: 4.672 ± 0.279
3.796ArgVal: 3.796 ± 0.63
1.46ArgTrp: 1.46 ± 0.491
2.336ArgTyr: 2.336 ± 0.784
0.0ArgXaa: 0.0 ± 0.0
Ser
7.007SerAla: 7.007 ± 0.418
1.46SerCys: 1.46 ± 0.491
3.796SerAsp: 3.796 ± 0.755
3.212SerGlu: 3.212 ± 0.711
3.212SerPhe: 3.212 ± 0.213
5.547SerGly: 5.547 ± 0.388
1.46SerHis: 1.46 ± 0.894
2.92SerIle: 2.92 ± 1.788
0.876SerLys: 0.876 ± 0.11
4.964SerLeu: 4.964 ± 0.469
1.752SerMet: 1.752 ± 0.22
2.044SerAsn: 2.044 ± 0.41
4.088SerPro: 4.088 ± 1.283
2.628SerGln: 2.628 ± 0.792
6.131SerArg: 6.131 ± 0.77
5.255SerSer: 5.255 ± 0.264
4.964SerThr: 4.964 ± 0.007
4.672SerVal: 4.672 ± 0.74
2.044SerTrp: 2.044 ± 0.41
1.46SerTyr: 1.46 ± 0.432
0.292SerXaa: 0.292 ± 0.191
Thr
5.547ThrAla: 5.547 ± 1.312
0.876ThrCys: 0.876 ± 0.352
2.628ThrAsp: 2.628 ± 0.132
2.628ThrGlu: 2.628 ± 0.33
1.168ThrPhe: 1.168 ± 0.623
5.839ThrGly: 5.839 ± 0.117
0.876ThrHis: 0.876 ± 0.11
0.876ThrIle: 0.876 ± 0.572
1.168ThrLys: 1.168 ± 0.623
4.964ThrLeu: 4.964 ± 0.007
0.876ThrMet: 0.876 ± 0.497
2.044ThrAsn: 2.044 ± 0.513
4.38ThrPro: 4.38 ± 0.088
0.876ThrGln: 0.876 ± 0.11
4.088ThrArg: 4.088 ± 1.026
4.088ThrSer: 4.088 ± 0.821
6.131ThrThr: 6.131 ± 0.154
4.964ThrVal: 4.964 ± 0.931
1.46ThrTrp: 1.46 ± 0.491
1.46ThrTyr: 1.46 ± 0.432
0.0ThrXaa: 0.0 ± 0.0
Val
6.423ValAla: 6.423 ± 0.96
1.752ValCys: 1.752 ± 0.242
6.715ValAsp: 6.715 ± 0.227
1.46ValGlu: 1.46 ± 0.029
2.628ValPhe: 2.628 ± 1.253
6.131ValGly: 6.131 ± 0.616
0.584ValHis: 0.584 ± 0.081
2.336ValIle: 2.336 ± 0.601
2.336ValLys: 2.336 ± 0.784
8.467ValLeu: 8.467 ± 0.909
0.876ValMet: 0.876 ± 0.456
1.752ValAsn: 1.752 ± 0.242
4.964ValPro: 4.964 ± 1.854
3.796ValGln: 3.796 ± 0.293
4.964ValArg: 4.964 ± 0.469
7.299ValSer: 7.299 ± 0.147
4.38ValThr: 4.38 ± 0.088
7.007ValVal: 7.007 ± 0.418
0.876ValTrp: 0.876 ± 0.352
2.92ValTyr: 2.92 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
2.044TrpAla: 2.044 ± 0.872
0.0TrpCys: 0.0 ± 0.0
1.752TrpAsp: 1.752 ± 0.242
1.46TrpGlu: 1.46 ± 0.491
0.0TrpPhe: 0.0 ± 0.0
0.292TrpGly: 0.292 ± 0.271
0.584TrpHis: 0.584 ± 0.381
0.584TrpIle: 0.584 ± 0.081
0.0TrpLys: 0.0 ± 0.0
3.504TrpLeu: 3.504 ± 0.484
0.292TrpMet: 0.292 ± 0.191
0.292TrpAsn: 0.292 ± 0.191
0.876TrpPro: 0.876 ± 0.352
0.584TrpGln: 0.584 ± 0.542
2.044TrpArg: 2.044 ± 0.051
1.168TrpSer: 1.168 ± 0.301
0.876TrpThr: 0.876 ± 0.11
1.46TrpVal: 1.46 ± 0.953
0.584TrpTrp: 0.584 ± 0.542
0.876TrpTyr: 0.876 ± 0.572
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.964TyrAla: 4.964 ± 1.378
0.0TyrCys: 0.0 ± 0.0
2.92TyrAsp: 2.92 ± 0.865
1.752TyrGlu: 1.752 ± 0.704
1.46TyrPhe: 1.46 ± 0.029
2.628TyrGly: 2.628 ± 0.132
1.752TyrHis: 1.752 ± 0.22
0.584TyrIle: 0.584 ± 0.081
0.292TyrLys: 0.292 ± 0.271
3.504TyrLeu: 3.504 ± 0.945
0.876TyrMet: 0.876 ± 0.572
0.876TyrAsn: 0.876 ± 0.352
2.336TyrPro: 2.336 ± 0.322
1.168TyrGln: 1.168 ± 0.623
2.336TyrArg: 2.336 ± 0.784
3.796TyrSer: 3.796 ± 1.217
1.752TyrThr: 1.752 ± 0.22
2.92TyrVal: 2.92 ± 1.327
0.292TyrTrp: 0.292 ± 0.271
1.168TyrTyr: 1.168 ± 0.623
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.292XaaPhe: 0.292 ± 0.191
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.292XaaThr: 0.292 ± 0.191
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3426 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski