Amino acid dipepetide frequency for Felis catus papillomavirus type 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.163AlaAla: 3.163 ± 1.142
0.395AlaCys: 0.395 ± 0.553
1.977AlaAsp: 1.977 ± 0.662
3.954AlaGlu: 3.954 ± 1.292
1.186AlaPhe: 1.186 ± 0.397
3.559AlaGly: 3.559 ± 1.209
0.791AlaHis: 0.791 ± 0.404
1.582AlaIle: 1.582 ± 0.722
5.14AlaLys: 5.14 ± 0.87
2.768AlaLeu: 2.768 ± 1.254
0.395AlaMet: 0.395 ± 0.353
1.582AlaAsn: 1.582 ± 0.76
2.768AlaPro: 2.768 ± 0.576
1.186AlaGln: 1.186 ± 0.737
1.186AlaArg: 1.186 ± 0.664
6.722AlaSer: 6.722 ± 0.895
2.372AlaThr: 2.372 ± 0.807
3.163AlaVal: 3.163 ± 1.045
0.395AlaTrp: 0.395 ± 0.363
1.977AlaTyr: 1.977 ± 0.92
0.0AlaXaa: 0.0 ± 0.0
Cys
1.582CysAla: 1.582 ± 0.938
1.582CysCys: 1.582 ± 1.215
1.186CysAsp: 1.186 ± 0.707
1.186CysGlu: 1.186 ± 0.612
1.582CysPhe: 1.582 ± 1.218
0.791CysGly: 0.791 ± 0.523
1.186CysHis: 1.186 ± 1.041
1.186CysIle: 1.186 ± 0.959
0.791CysLys: 0.791 ± 0.449
2.768CysLeu: 2.768 ± 1.458
0.395CysMet: 0.395 ± 0.553
0.791CysAsn: 0.791 ± 0.726
1.582CysPro: 1.582 ± 0.748
0.395CysGln: 0.395 ± 0.502
1.186CysArg: 1.186 ± 1.101
0.791CysSer: 0.791 ± 0.705
1.977CysThr: 1.977 ± 1.171
1.977CysVal: 1.977 ± 0.875
1.582CysTrp: 1.582 ± 0.783
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.372AspAla: 2.372 ± 1.211
3.954AspCys: 3.954 ± 1.342
2.372AspAsp: 2.372 ± 0.844
5.931AspGlu: 5.931 ± 2.655
3.559AspPhe: 3.559 ± 1.072
2.768AspGly: 2.768 ± 0.792
0.791AspHis: 0.791 ± 0.523
3.163AspIle: 3.163 ± 1.254
1.582AspLys: 1.582 ± 0.75
4.745AspLeu: 4.745 ± 0.92
0.395AspMet: 0.395 ± 0.353
3.163AspAsn: 3.163 ± 1.331
4.35AspPro: 4.35 ± 2.758
1.977AspGln: 1.977 ± 0.863
0.791AspArg: 0.791 ± 0.705
4.745AspSer: 4.745 ± 1.612
2.768AspThr: 2.768 ± 1.055
4.35AspVal: 4.35 ± 1.308
2.372AspTrp: 2.372 ± 0.774
0.395AspTyr: 0.395 ± 0.363
0.0AspXaa: 0.0 ± 0.0
Glu
1.977GluAla: 1.977 ± 0.845
0.791GluCys: 0.791 ± 0.609
7.908GluAsp: 7.908 ± 2.819
9.095GluGlu: 9.095 ± 3.028
0.791GluPhe: 0.791 ± 0.416
4.745GluGly: 4.745 ± 1.428
1.186GluHis: 1.186 ± 0.397
2.768GluIle: 2.768 ± 1.726
2.372GluLys: 2.372 ± 1.059
5.536GluLeu: 5.536 ± 1.626
0.791GluMet: 0.791 ± 0.375
3.559GluAsn: 3.559 ± 0.809
3.559GluPro: 3.559 ± 0.651
1.977GluGln: 1.977 ± 1.057
2.768GluArg: 2.768 ± 1.008
4.35GluSer: 4.35 ± 1.342
5.536GluThr: 5.536 ± 1.322
5.536GluVal: 5.536 ± 1.181
1.977GluTrp: 1.977 ± 0.948
1.186GluTyr: 1.186 ± 0.397
0.0GluXaa: 0.0 ± 0.0
Phe
1.582PheAla: 1.582 ± 0.5
0.395PheCys: 0.395 ± 0.553
2.768PheAsp: 2.768 ± 0.885
2.768PheGlu: 2.768 ± 1.103
1.977PhePhe: 1.977 ± 1.42
2.372PheGly: 2.372 ± 0.684
0.791PheHis: 0.791 ± 0.432
1.186PheIle: 1.186 ± 0.544
3.559PheLys: 3.559 ± 1.967
3.559PheLeu: 3.559 ± 0.85
0.395PheMet: 0.395 ± 0.351
1.186PheAsn: 1.186 ± 0.632
1.186PhePro: 1.186 ± 0.415
2.372PheGln: 2.372 ± 1.272
0.395PheArg: 0.395 ± 0.363
3.559PheSer: 3.559 ± 0.815
1.582PheThr: 1.582 ± 0.683
2.768PheVal: 2.768 ± 0.934
0.791PheTrp: 0.791 ± 0.449
1.977PheTyr: 1.977 ± 0.786
0.0PheXaa: 0.0 ± 0.0
Gly
6.327GlyAla: 6.327 ± 1.136
2.768GlyCys: 2.768 ± 1.645
6.327GlyAsp: 6.327 ± 1.93
5.536GlyGlu: 5.536 ± 1.977
3.163GlyPhe: 3.163 ± 0.842
12.653GlyGly: 12.653 ± 4.468
1.582GlyHis: 1.582 ± 0.812
2.372GlyIle: 2.372 ± 0.837
5.14GlyLys: 5.14 ± 1.72
6.327GlyLeu: 6.327 ± 1.005
0.395GlyMet: 0.395 ± 0.363
2.768GlyAsn: 2.768 ± 1.13
2.768GlyPro: 2.768 ± 0.723
4.35GlyGln: 4.35 ± 1.562
8.699GlyArg: 8.699 ± 3.698
6.327GlySer: 6.327 ± 1.041
5.536GlyThr: 5.536 ± 1.982
5.536GlyVal: 5.536 ± 1.203
0.0GlyTrp: 0.0 ± 0.0
2.372GlyTyr: 2.372 ± 0.36
0.0GlyXaa: 0.0 ± 0.0
His
0.395HisAla: 0.395 ± 0.319
2.768HisCys: 2.768 ± 1.257
0.0HisAsp: 0.0 ± 0.0
0.791HisGlu: 0.791 ± 0.701
0.791HisPhe: 0.791 ± 0.375
2.372HisGly: 2.372 ± 1.408
1.186HisHis: 1.186 ± 0.776
0.395HisIle: 0.395 ± 0.319
0.791HisLys: 0.791 ± 0.375
1.582HisLeu: 1.582 ± 1.209
0.395HisMet: 0.395 ± 0.353
0.0HisAsn: 0.0 ± 0.0
1.977HisPro: 1.977 ± 1.453
0.395HisGln: 0.395 ± 0.363
3.163HisArg: 3.163 ± 1.165
1.977HisSer: 1.977 ± 1.202
0.395HisThr: 0.395 ± 0.363
1.186HisVal: 1.186 ± 0.707
0.395HisTrp: 0.395 ± 0.353
1.582HisTyr: 1.582 ± 1.025
0.0HisXaa: 0.0 ± 0.0
Ile
1.582IleAla: 1.582 ± 0.564
1.186IleCys: 1.186 ± 0.572
1.582IleAsp: 1.582 ± 0.75
2.768IleGlu: 2.768 ± 0.996
1.186IlePhe: 1.186 ± 0.703
4.35IleGly: 4.35 ± 1.772
0.791IleHis: 0.791 ± 0.449
2.372IleIle: 2.372 ± 1.314
2.372IleLys: 2.372 ± 0.533
4.35IleLeu: 4.35 ± 0.917
0.791IleMet: 0.791 ± 1.005
1.582IleAsn: 1.582 ± 0.342
1.977IlePro: 1.977 ± 1.047
0.791IleGln: 0.791 ± 0.609
1.186IleArg: 1.186 ± 0.828
2.768IleSer: 2.768 ± 0.989
0.791IleThr: 0.791 ± 0.449
2.768IleVal: 2.768 ± 1.78
0.0IleTrp: 0.0 ± 0.0
0.791IleTyr: 0.791 ± 0.404
0.0IleXaa: 0.0 ± 0.0
Lys
1.186LysAla: 1.186 ± 1.101
1.186LysCys: 1.186 ± 0.704
1.582LysAsp: 1.582 ± 0.738
3.163LysGlu: 3.163 ± 0.869
1.582LysPhe: 1.582 ± 0.651
3.954LysGly: 3.954 ± 0.767
1.186LysHis: 1.186 ± 0.401
1.186LysIle: 1.186 ± 0.643
2.372LysLys: 2.372 ± 0.77
4.35LysLeu: 4.35 ± 2.189
1.582LysMet: 1.582 ± 0.649
2.768LysAsn: 2.768 ± 0.803
1.977LysPro: 1.977 ± 1.179
3.163LysGln: 3.163 ± 0.867
5.536LysArg: 5.536 ± 1.254
2.768LysSer: 2.768 ± 1.276
2.372LysThr: 2.372 ± 0.725
2.372LysVal: 2.372 ± 0.974
0.0LysTrp: 0.0 ± 0.0
2.372LysTyr: 2.372 ± 1.774
0.0LysXaa: 0.0 ± 0.0
Leu
3.954LeuAla: 3.954 ± 1.455
2.372LeuCys: 2.372 ± 1.273
4.35LeuAsp: 4.35 ± 0.957
3.954LeuGlu: 3.954 ± 1.316
4.35LeuPhe: 4.35 ± 1.244
11.072LeuGly: 11.072 ± 1.811
3.163LeuHis: 3.163 ± 0.909
0.791LeuIle: 0.791 ± 0.523
3.163LeuLys: 3.163 ± 1.155
7.117LeuLeu: 7.117 ± 2.522
2.372LeuMet: 2.372 ± 0.864
3.163LeuAsn: 3.163 ± 1.181
3.954LeuPro: 3.954 ± 0.796
6.327LeuGln: 6.327 ± 1.378
6.327LeuArg: 6.327 ± 1.965
5.536LeuSer: 5.536 ± 1.025
6.327LeuThr: 6.327 ± 1.199
5.931LeuVal: 5.931 ± 1.163
1.582LeuTrp: 1.582 ± 0.5
3.559LeuTyr: 3.559 ± 0.663
0.0LeuXaa: 0.0 ± 0.0
Met
1.582MetAla: 1.582 ± 1.137
0.395MetCys: 0.395 ± 0.353
0.395MetAsp: 0.395 ± 0.353
0.791MetGlu: 0.791 ± 0.432
1.186MetPhe: 1.186 ± 0.707
1.582MetGly: 1.582 ± 0.777
0.395MetHis: 0.395 ± 0.502
0.395MetIle: 0.395 ± 0.515
0.791MetLys: 0.791 ± 0.523
0.395MetLeu: 0.395 ± 0.502
0.395MetMet: 0.395 ± 0.502
0.791MetAsn: 0.791 ± 0.705
1.186MetPro: 1.186 ± 0.666
0.791MetGln: 0.791 ± 0.404
1.582MetArg: 1.582 ± 0.808
2.768MetSer: 2.768 ± 0.776
0.395MetThr: 0.395 ± 0.363
1.186MetVal: 1.186 ± 0.747
0.395MetTrp: 0.395 ± 0.502
0.791MetTyr: 0.791 ± 0.416
0.0MetXaa: 0.0 ± 0.0
Asn
1.582AsnAla: 1.582 ± 0.808
0.395AsnCys: 0.395 ± 0.363
1.977AsnAsp: 1.977 ± 0.429
1.977AsnGlu: 1.977 ± 0.944
2.372AsnPhe: 2.372 ± 1.348
1.186AsnGly: 1.186 ± 0.722
0.0AsnHis: 0.0 ± 0.0
2.372AsnIle: 2.372 ± 1.235
2.768AsnLys: 2.768 ± 1.366
2.768AsnLeu: 2.768 ± 0.995
1.186AsnMet: 1.186 ± 0.406
2.372AsnAsn: 2.372 ± 0.651
2.372AsnPro: 2.372 ± 1.062
1.977AsnGln: 1.977 ± 0.824
1.582AsnArg: 1.582 ± 0.649
3.163AsnSer: 3.163 ± 1.353
2.372AsnThr: 2.372 ± 1.405
2.768AsnVal: 2.768 ± 0.998
0.395AsnTrp: 0.395 ± 0.351
0.791AsnTyr: 0.791 ± 0.449
0.0AsnXaa: 0.0 ± 0.0
Pro
5.14ProAla: 5.14 ± 1.951
0.791ProCys: 0.791 ± 0.705
4.35ProAsp: 4.35 ± 1.134
4.35ProGlu: 4.35 ± 0.842
1.186ProPhe: 1.186 ± 0.415
3.559ProGly: 3.559 ± 1.878
1.582ProHis: 1.582 ± 1.016
1.977ProIle: 1.977 ± 0.515
2.372ProLys: 2.372 ± 0.881
6.327ProLeu: 6.327 ± 1.44
0.791ProMet: 0.791 ± 0.705
1.582ProAsn: 1.582 ± 0.651
7.117ProPro: 7.117 ± 3.425
0.791ProGln: 0.791 ± 0.558
3.559ProArg: 3.559 ± 0.906
5.536ProSer: 5.536 ± 1.709
2.768ProThr: 2.768 ± 1.366
3.163ProVal: 3.163 ± 1.854
0.791ProTrp: 0.791 ± 0.404
1.582ProTyr: 1.582 ± 1.03
0.0ProXaa: 0.0 ± 0.0
Gln
1.977GlnAla: 1.977 ± 0.958
1.186GlnCys: 1.186 ± 1.089
2.768GlnAsp: 2.768 ± 1.012
3.559GlnGlu: 3.559 ± 1.089
1.582GlnPhe: 1.582 ± 0.649
2.768GlnGly: 2.768 ± 0.765
0.791GlnHis: 0.791 ± 0.523
1.977GlnIle: 1.977 ± 1.01
0.791GlnLys: 0.791 ± 0.523
3.954GlnLeu: 3.954 ± 1.232
1.186GlnMet: 1.186 ± 0.545
0.395GlnAsn: 0.395 ± 0.353
1.977GlnPro: 1.977 ± 0.878
3.559GlnGln: 3.559 ± 0.817
2.768GlnArg: 2.768 ± 1.133
3.559GlnSer: 3.559 ± 0.624
1.186GlnThr: 1.186 ± 0.561
3.954GlnVal: 3.954 ± 1.136
1.186GlnTrp: 1.186 ± 0.415
0.791GlnTyr: 0.791 ± 0.416
0.0GlnXaa: 0.0 ± 0.0
Arg
3.163ArgAla: 3.163 ± 1.259
1.977ArgCys: 1.977 ± 1.348
1.977ArgAsp: 1.977 ± 0.73
4.35ArgGlu: 4.35 ± 0.84
1.186ArgPhe: 1.186 ± 0.514
7.117ArgGly: 7.117 ± 4.362
2.768ArgHis: 2.768 ± 0.927
2.768ArgIle: 2.768 ± 1.13
3.559ArgLys: 3.559 ± 0.984
8.699ArgLeu: 8.699 ± 1.987
0.395ArgMet: 0.395 ± 0.515
1.977ArgAsn: 1.977 ± 0.786
3.163ArgPro: 3.163 ± 0.737
3.954ArgGln: 3.954 ± 1.046
5.536ArgArg: 5.536 ± 1.925
3.954ArgSer: 3.954 ± 0.872
2.372ArgThr: 2.372 ± 0.677
3.954ArgVal: 3.954 ± 1.568
1.186ArgTrp: 1.186 ± 1.002
0.791ArgTyr: 0.791 ± 0.375
0.0ArgXaa: 0.0 ± 0.0
Ser
1.582SerAla: 1.582 ± 0.649
0.791SerCys: 0.791 ± 0.586
3.559SerAsp: 3.559 ± 1.334
4.745SerGlu: 4.745 ± 1.271
3.163SerPhe: 3.163 ± 1.525
9.885SerGly: 9.885 ± 1.919
2.372SerHis: 2.372 ± 1.571
4.745SerIle: 4.745 ± 0.876
3.163SerLys: 3.163 ± 1.671
7.513SerLeu: 7.513 ± 1.79
1.977SerMet: 1.977 ± 0.931
2.768SerAsn: 2.768 ± 0.818
6.327SerPro: 6.327 ± 2.224
2.768SerGln: 2.768 ± 0.825
5.14SerArg: 5.14 ± 0.873
11.072SerSer: 11.072 ± 2.992
7.117SerThr: 7.117 ± 1.887
6.327SerVal: 6.327 ± 1.241
1.186SerTrp: 1.186 ± 0.756
2.768SerTyr: 2.768 ± 0.678
0.0SerXaa: 0.0 ± 0.0
Thr
2.372ThrAla: 2.372 ± 0.943
1.186ThrCys: 1.186 ± 0.778
2.768ThrAsp: 2.768 ± 0.54
4.745ThrGlu: 4.745 ± 1.675
2.372ThrPhe: 2.372 ± 0.89
7.117ThrGly: 7.117 ± 1.616
0.395ThrHis: 0.395 ± 0.353
0.791ThrIle: 0.791 ± 0.573
2.372ThrLys: 2.372 ± 1.055
5.536ThrLeu: 5.536 ± 1.535
1.186ThrMet: 1.186 ± 0.959
1.582ThrAsn: 1.582 ± 0.703
4.35ThrPro: 4.35 ± 1.74
1.977ThrGln: 1.977 ± 1.371
3.163ThrArg: 3.163 ± 0.715
6.722ThrSer: 6.722 ± 1.658
3.163ThrThr: 3.163 ± 1.274
5.14ThrVal: 5.14 ± 0.802
0.0ThrTrp: 0.0 ± 0.0
1.186ThrTyr: 1.186 ± 0.549
0.0ThrXaa: 0.0 ± 0.0
Val
2.768ValAla: 2.768 ± 1.803
0.395ValCys: 0.395 ± 0.353
5.931ValAsp: 5.931 ± 0.802
2.768ValGlu: 2.768 ± 1.245
2.768ValPhe: 2.768 ± 0.773
6.722ValGly: 6.722 ± 2.35
0.791ValHis: 0.791 ± 0.462
1.977ValIle: 1.977 ± 0.523
0.791ValLys: 0.791 ± 0.609
6.327ValLeu: 6.327 ± 1.055
1.186ValMet: 1.186 ± 0.397
2.372ValAsn: 2.372 ± 0.801
5.14ValPro: 5.14 ± 1.242
1.977ValGln: 1.977 ± 0.845
6.327ValArg: 6.327 ± 2.244
8.699ValSer: 8.699 ± 2.013
6.327ValThr: 6.327 ± 0.871
5.14ValVal: 5.14 ± 1.558
0.395ValTrp: 0.395 ± 0.353
1.186ValTyr: 1.186 ± 0.704
0.0ValXaa: 0.0 ± 0.0
Trp
0.791TrpAla: 0.791 ± 0.404
0.0TrpCys: 0.0 ± 0.0
1.186TrpAsp: 1.186 ± 0.722
0.791TrpGlu: 0.791 ± 0.701
0.0TrpPhe: 0.0 ± 0.0
0.395TrpGly: 0.395 ± 0.502
0.0TrpHis: 0.0 ± 0.0
1.186TrpIle: 1.186 ± 0.683
0.791TrpLys: 0.791 ± 0.404
1.582TrpLeu: 1.582 ± 1.071
0.791TrpMet: 0.791 ± 0.764
0.395TrpAsn: 0.395 ± 0.353
0.395TrpPro: 0.395 ± 0.319
0.0TrpGln: 0.0 ± 0.0
2.372TrpArg: 2.372 ± 1.14
1.977TrpSer: 1.977 ± 0.738
1.186TrpThr: 1.186 ± 1.002
1.186TrpVal: 1.186 ± 0.572
0.0TrpTrp: 0.0 ± 0.0
0.791TrpTyr: 0.791 ± 0.404
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.186TyrAla: 1.186 ± 0.415
0.0TyrCys: 0.0 ± 0.0
1.582TyrAsp: 1.582 ± 0.651
1.186TyrGlu: 1.186 ± 0.401
1.186TyrPhe: 1.186 ± 0.474
1.977TyrGly: 1.977 ± 0.867
0.791TyrHis: 0.791 ± 0.416
0.791TyrIle: 0.791 ± 0.449
1.977TyrLys: 1.977 ± 0.523
3.559TyrLeu: 3.559 ± 1.749
0.791TyrMet: 0.791 ± 0.523
1.582TyrAsn: 1.582 ± 0.637
1.186TyrPro: 1.186 ± 0.474
1.186TyrGln: 1.186 ± 0.683
1.582TyrArg: 1.582 ± 0.5
1.977TyrSer: 1.977 ± 1.42
1.582TyrThr: 1.582 ± 0.793
1.582TyrVal: 1.582 ± 0.624
1.186TyrTrp: 1.186 ± 0.707
1.186TyrTyr: 1.186 ± 1.052
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2530 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski