Average proteome isoelectric point is 6.06

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

    

All

Note: above files contain also dissociation constants (pKa)

Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

    

>tr|A0A172KP16|A0A172KP16_9VIRU Replicase OS=Hantaan orthohantavirus OX=1980471 PE=4 SV=1
MM1 pKa = 7.67GIWKK5 pKa = 8.63WLVMASLVWPVLTLRR20 pKa = 11.84NVYY23 pKa = 10.19DD24 pKa = 3.78MKK26 pKa = 10.59IEE28 pKa = 4.44CPHH31 pKa = 5.59TVSFGEE37 pKa = 3.96NSVIGYY43 pKa = 9.52VEE45 pKa = 4.89LPPMPLADD53 pKa = 3.77TAQMVPEE60 pKa = 5.12SSCSMDD66 pKa = 2.74NHH68 pKa = 6.28QSLNTITKK76 pKa = 6.92YY77 pKa = 8.81TQVSWRR83 pKa = 11.84GKK85 pKa = 10.17ADD87 pKa = 3.39QSQSNQNSFEE97 pKa = 4.35TVSTEE102 pKa = 3.43VDD104 pKa = 3.33LKK106 pKa = 9.15GTCVLKK112 pKa = 10.76HH113 pKa = 6.08KK114 pKa = 9.84MVEE117 pKa = 3.45EE118 pKa = 4.67SYY120 pKa = 10.8RR121 pKa = 11.84SRR123 pKa = 11.84KK124 pKa = 10.23SITCYY129 pKa = 10.62DD130 pKa = 4.15LSCNSTYY137 pKa = 10.67CKK139 pKa = 8.37PTLYY143 pKa = 10.09MIVPIHH149 pKa = 6.86ACNMMKK155 pKa = 10.08SCLIALGPYY164 pKa = 9.06RR165 pKa = 11.84VQVVYY170 pKa = 10.76EE171 pKa = 3.92RR172 pKa = 11.84TYY174 pKa = 11.57CMTGVLIEE182 pKa = 4.54GKK184 pKa = 10.3CFVPDD189 pKa = 3.41QSVVSIIKK197 pKa = 10.33HH198 pKa = 5.97GIFDD202 pKa = 3.7IASVHH207 pKa = 5.58IVCFFVAVKK216 pKa = 10.69GNTYY220 pKa = 10.49KK221 pKa = 10.48IFEE224 pKa = 4.2QVKK227 pKa = 9.6KK228 pKa = 10.84SFEE231 pKa = 4.33STCNDD236 pKa = 3.4TEE238 pKa = 4.36NKK240 pKa = 8.28VQGYY244 pKa = 6.92YY245 pKa = 9.96ICIVGGNSAPIYY257 pKa = 10.91VPTLDD262 pKa = 4.74DD263 pKa = 3.92FRR265 pKa = 11.84SMEE268 pKa = 4.15AFTGIFRR275 pKa = 11.84SPHH278 pKa = 6.41GEE280 pKa = 3.84DD281 pKa = 3.28HH282 pKa = 7.31DD283 pKa = 4.64LAGEE287 pKa = 4.46EE288 pKa = 3.99IATYY292 pKa = 10.48SIVGPANAKK301 pKa = 9.49VPHH304 pKa = 6.31SASSDD309 pKa = 3.64TLSLIAYY316 pKa = 9.26SGIPSYY322 pKa = 11.41SSLSILTSSTEE333 pKa = 3.9AKK335 pKa = 10.25HH336 pKa = 5.87VFSPGLFPKK345 pKa = 10.52LNHH348 pKa = 5.85TNCDD352 pKa = 3.01KK353 pKa = 11.25SAIPLMWTGMIDD365 pKa = 3.49LPGYY369 pKa = 9.83YY370 pKa = 9.59EE371 pKa = 4.61AVHH374 pKa = 6.8PCTVFCVLSGPGASCEE390 pKa = 4.02AFSEE394 pKa = 4.39GGIFNITSPMCLVSKK409 pKa = 8.96QNRR412 pKa = 11.84FRR414 pKa = 11.84LTEE417 pKa = 3.66QQVNFVCQRR426 pKa = 11.84VDD428 pKa = 2.9VDD430 pKa = 3.49IVVYY434 pKa = 10.88CNGQRR439 pKa = 11.84KK440 pKa = 9.52VILTKK445 pKa = 10.2TLVIGQCIYY454 pKa = 10.71TITSLFSLLPGVAHH468 pKa = 6.96SIAVEE473 pKa = 3.89LCVPGFHH480 pKa = 6.59GWATAALLVTFCFGWVLIPAITFIILTILKK510 pKa = 9.17FIANIFHH517 pKa = 7.07TSNQEE522 pKa = 3.6NRR524 pKa = 11.84LKK526 pKa = 10.93SVLRR530 pKa = 11.84KK531 pKa = 9.66IKK533 pKa = 10.75EE534 pKa = 4.04EE535 pKa = 3.91FEE537 pKa = 4.15KK538 pKa = 10.52TKK540 pKa = 10.98GSMVCDD546 pKa = 3.43VCKK549 pKa = 10.97YY550 pKa = 9.33EE551 pKa = 4.31CEE553 pKa = 4.26TYY555 pKa = 10.6KK556 pKa = 10.42EE557 pKa = 4.15LKK559 pKa = 9.85AHH561 pKa = 6.5GVSCPQSQCPYY572 pKa = 9.99CFTHH576 pKa = 7.17CEE578 pKa = 3.86PTEE581 pKa = 4.02AAFQAHH587 pKa = 5.78YY588 pKa = 10.15KK589 pKa = 9.07VCQVTHH595 pKa = 7.24RR596 pKa = 11.84FRR598 pKa = 11.84DD599 pKa = 3.86DD600 pKa = 3.26LKK602 pKa = 10.92KK603 pKa = 9.22TVTPQNFTPGCYY615 pKa = 7.94RR616 pKa = 11.84TLNLFRR622 pKa = 11.84YY623 pKa = 9.62KK624 pKa = 10.13SRR626 pKa = 11.84CYY628 pKa = 10.25IFTMWIFLLVLEE640 pKa = 4.98SILWAASASEE650 pKa = 4.35TPLTPVWNDD659 pKa = 2.81NAHH662 pKa = 6.04GVGSVPMHH670 pKa = 6.9TDD672 pKa = 3.38LEE674 pKa = 4.74LDD676 pKa = 4.08FSLTSSSKK684 pKa = 7.78YY685 pKa = 7.56TYY687 pKa = 9.93RR688 pKa = 11.84RR689 pKa = 11.84KK690 pKa = 8.94LTNPLEE696 pKa = 4.31EE697 pKa = 4.29AQSIDD702 pKa = 3.25LHH704 pKa = 8.22IEE706 pKa = 3.63IEE708 pKa = 4.19EE709 pKa = 3.92QTIGVDD715 pKa = 3.61VHH717 pKa = 7.72ALGHH721 pKa = 5.93WFDD724 pKa = 3.78GRR726 pKa = 11.84LNLKK730 pKa = 9.26TSFHH734 pKa = 7.19CYY736 pKa = 9.2GACTKK741 pKa = 10.66YY742 pKa = 10.35EE743 pKa = 4.4YY744 pKa = 9.54PWHH747 pKa = 5.74TAKK750 pKa = 10.43CHH752 pKa = 5.01YY753 pKa = 10.04EE754 pKa = 3.52RR755 pKa = 11.84DD756 pKa = 3.98YY757 pKa = 11.28QYY759 pKa = 8.98EE760 pKa = 4.31TSWGCNPSDD769 pKa = 4.09CPGVGTGCTACGLYY783 pKa = 10.31LDD785 pKa = 3.88QLKK788 pKa = 10.23PVGSAYY794 pKa = 9.82KK795 pKa = 10.1IITIRR800 pKa = 11.84YY801 pKa = 6.85SRR803 pKa = 11.84RR804 pKa = 11.84VCVQFGEE811 pKa = 4.33EE812 pKa = 4.2NLCKK816 pKa = 10.14IIDD819 pKa = 3.8MNDD822 pKa = 3.39CFVSRR827 pKa = 11.84HH828 pKa = 4.95VKK830 pKa = 9.19VCIIGTVSKK839 pKa = 10.31FSQGDD844 pKa = 3.47TLLFFGPLEE853 pKa = 4.46GGGLIFKK860 pKa = 8.9HH861 pKa = 5.91WCTSTCQFGDD871 pKa = 3.7PGDD874 pKa = 3.65IMSPRR879 pKa = 11.84DD880 pKa = 3.48KK881 pKa = 11.4GFLCPEE887 pKa = 4.21FPGSFRR893 pKa = 11.84KK894 pKa = 9.74KK895 pKa = 10.43CNFATTPICEE905 pKa = 4.1YY906 pKa = 10.3DD907 pKa = 3.34GNMVSGYY914 pKa = 9.12KK915 pKa = 10.03KK916 pKa = 10.84VMATIDD922 pKa = 3.57SFQSFNTSTMHH933 pKa = 5.96FTDD936 pKa = 5.65EE937 pKa = 4.43RR938 pKa = 11.84IEE940 pKa = 4.09WKK942 pKa = 10.67DD943 pKa = 3.21PDD945 pKa = 3.88GMLRR949 pKa = 11.84DD950 pKa = 4.58HH951 pKa = 7.25INILVTKK958 pKa = 10.47DD959 pKa = 2.92IDD961 pKa = 3.88FDD963 pKa = 4.09NLGEE967 pKa = 4.15NPCKK971 pKa = 10.19IGLQTSSIEE980 pKa = 4.28GAWGSGVGFTLTCLVSLTEE999 pKa = 4.65CPTFLTSIKK1008 pKa = 10.51ACDD1011 pKa = 3.25KK1012 pKa = 10.23AICYY1016 pKa = 9.4GAEE1019 pKa = 4.18SVTLTRR1025 pKa = 11.84GQNTVKK1031 pKa = 10.51VSGKK1035 pKa = 9.65GGHH1038 pKa = 6.11SGSTFKK1044 pKa = 10.88CCHH1047 pKa = 6.47GEE1049 pKa = 3.95DD1050 pKa = 3.98CSQIGLHH1057 pKa = 6.13AAAPHH1062 pKa = 6.29LDD1064 pKa = 3.28KK1065 pKa = 11.73VNGISEE1071 pKa = 4.29MEE1073 pKa = 3.93NSKK1076 pKa = 10.91VYY1078 pKa = 10.77DD1079 pKa = 4.52DD1080 pKa = 5.12GAPQCGIKK1088 pKa = 10.16CWFVKK1093 pKa = 10.08SGEE1096 pKa = 4.17WISGIFSGNWIVLIVLCVFLLFSLVLLSILCPVRR1130 pKa = 11.84KK1131 pKa = 9.36HH1132 pKa = 6.06KK1133 pKa = 10.79KK1134 pKa = 8.64SS1135 pKa = 3.23

Molecular weight: 126.49 kDa
Isoelectric point according different methods:

>tr|A0A172KP16|A0A172KP16_9VIRU Replicase OS=Hantaan orthohantavirus OX=1980471 PE=4 SV=1
MM1 pKa = 7.85DD2 pKa = 5.3KK3 pKa = 10.7YY4 pKa = 11.11RR5 pKa = 11.84EE6 pKa = 3.91IHH8 pKa = 6.21NKK10 pKa = 9.93LKK12 pKa = 10.46EE13 pKa = 4.11FSPGTLTAVEE23 pKa = 4.86CIDD26 pKa = 3.72YY27 pKa = 10.78LDD29 pKa = 3.69RR30 pKa = 11.84LYY32 pKa = 11.04AVRR35 pKa = 11.84HH36 pKa = 6.33DD37 pKa = 5.02IVDD40 pKa = 3.44QMIKK44 pKa = 10.34HH45 pKa = 6.53DD46 pKa = 3.55WSDD49 pKa = 3.45NKK51 pKa = 10.84DD52 pKa = 3.38SEE54 pKa = 4.27EE55 pKa = 4.75AIGKK59 pKa = 9.05VLLFAGVPSNIITALEE75 pKa = 3.84KK76 pKa = 10.64KK77 pKa = 10.13IIPNHH82 pKa = 5.47PTGKK86 pKa = 9.6SLKK89 pKa = 10.01AFFKK93 pKa = 7.7MTPDD97 pKa = 3.08NYY99 pKa = 10.24KK100 pKa = 10.23ISGTTIEE107 pKa = 4.34FVEE110 pKa = 4.58VTVTADD116 pKa = 2.72VDD118 pKa = 3.34KK119 pKa = 11.29GIRR122 pKa = 11.84EE123 pKa = 4.09KK124 pKa = 10.8KK125 pKa = 9.94LKK127 pKa = 10.77YY128 pKa = 9.61EE129 pKa = 4.41AGLTYY134 pKa = 9.88IEE136 pKa = 4.31QEE138 pKa = 3.87LHH140 pKa = 6.57KK141 pKa = 10.49FFLKK145 pKa = 11.04GEE147 pKa = 3.94IPQPYY152 pKa = 9.41KK153 pKa = 9.92ITFTVVAVRR162 pKa = 11.84TDD164 pKa = 3.13GSNITTQWPSRR175 pKa = 11.84RR176 pKa = 11.84NDD178 pKa = 3.02GVVQYY183 pKa = 9.77MRR185 pKa = 11.84LVQAEE190 pKa = 3.73ISYY193 pKa = 10.19VRR195 pKa = 11.84EE196 pKa = 3.79HH197 pKa = 7.15LIKK200 pKa = 10.01TEE202 pKa = 3.56EE203 pKa = 4.04RR204 pKa = 11.84AALEE208 pKa = 4.02AMFNLKK214 pKa = 10.49FNISTHH220 pKa = 6.08KK221 pKa = 9.86SQPYY225 pKa = 9.1YY226 pKa = 10.17IPDD229 pKa = 3.73YY230 pKa = 11.07KK231 pKa = 11.47GMDD234 pKa = 4.2PIGANIEE241 pKa = 4.26DD242 pKa = 3.76LVDD245 pKa = 4.3YY246 pKa = 10.83SKK248 pKa = 11.16EE249 pKa = 3.8WLSRR253 pKa = 11.84ARR255 pKa = 11.84NFSFFEE261 pKa = 4.21VKK263 pKa = 8.91GTAVFEE269 pKa = 4.47CFNSNEE275 pKa = 4.01ANHH278 pKa = 5.8CQRR281 pKa = 11.84YY282 pKa = 8.08PMSRR286 pKa = 11.84KK287 pKa = 8.76PRR289 pKa = 11.84NFLLIQCSLITSYY302 pKa = 11.2KK303 pKa = 9.75PATTLSDD310 pKa = 3.52QIDD313 pKa = 3.53SRR315 pKa = 11.84RR316 pKa = 11.84ACSYY320 pKa = 10.36ILNLIPDD327 pKa = 4.47TPASYY332 pKa = 10.37LIHH335 pKa = 7.34DD336 pKa = 3.64MAYY339 pKa = 10.32RR340 pKa = 11.84YY341 pKa = 10.08INLTRR346 pKa = 11.84EE347 pKa = 3.95DD348 pKa = 4.22MINYY352 pKa = 6.74YY353 pKa = 10.59APRR356 pKa = 11.84IQFKK360 pKa = 7.88QTQNIRR366 pKa = 11.84EE367 pKa = 4.29PGTFKK372 pKa = 10.33LTSSMLRR379 pKa = 11.84AEE381 pKa = 4.57SKK383 pKa = 11.46AMLDD387 pKa = 3.66LLNNHH392 pKa = 6.85KK393 pKa = 10.77SGEE396 pKa = 4.03KK397 pKa = 9.92HH398 pKa = 5.11GAQIEE403 pKa = 4.51SLNIASHH410 pKa = 6.31IVQSEE415 pKa = 4.5SVSLITKK422 pKa = 9.82ILSDD426 pKa = 4.06LEE428 pKa = 4.54LNITEE433 pKa = 5.18PSTQEE438 pKa = 3.76YY439 pKa = 8.07STTKK443 pKa = 8.22HH444 pKa = 5.68TYY446 pKa = 10.05VDD448 pKa = 3.55TVLDD452 pKa = 3.66KK453 pKa = 10.89FFQNEE458 pKa = 4.12TQKK461 pKa = 11.58YY462 pKa = 9.75LIDD465 pKa = 3.77VLKK468 pKa = 9.71KK469 pKa = 6.58TTAWHH474 pKa = 6.1IGHH477 pKa = 8.49LIRR480 pKa = 11.84DD481 pKa = 3.65ITEE484 pKa = 3.77SLIAHH489 pKa = 6.61SGLKK493 pKa = 9.57RR494 pKa = 11.84SKK496 pKa = 8.49YY497 pKa = 9.32WSLHH501 pKa = 5.29SYY503 pKa = 11.11NNGNVILFILPSKK516 pKa = 9.94SLEE519 pKa = 4.11VAGSFIRR526 pKa = 11.84FITVFRR532 pKa = 11.84IGPGLVDD539 pKa = 4.93KK540 pKa = 11.33DD541 pKa = 3.9NLDD544 pKa = 4.03TILIDD549 pKa = 5.54GDD551 pKa = 4.36SQWGVSKK558 pKa = 11.17VMSIDD563 pKa = 3.79LNRR566 pKa = 11.84LLALNIAFEE575 pKa = 4.29KK576 pKa = 10.99ALIATATWFQYY587 pKa = 8.65YY588 pKa = 8.96TEE590 pKa = 4.89DD591 pKa = 3.27QGQFPLQYY599 pKa = 10.6AVRR602 pKa = 11.84SVFANHH608 pKa = 6.61FLLAVCQKK616 pKa = 9.8MKK618 pKa = 10.67LCAIFDD624 pKa = 3.77NLRR627 pKa = 11.84YY628 pKa = 9.94LIPAVTSLYY637 pKa = 10.89SGFPSLIEE645 pKa = 3.95KK646 pKa = 10.46LFEE649 pKa = 4.32RR650 pKa = 11.84PFKK653 pKa = 10.97SSLEE657 pKa = 3.84VYY659 pKa = 9.74IYY661 pKa = 11.14YY662 pKa = 10.32NIKK665 pKa = 10.27SLLVALAQNNKK676 pKa = 9.25ARR678 pKa = 11.84FYY680 pKa = 11.44SKK682 pKa = 11.01VKK684 pKa = 10.66LLGLTVDD691 pKa = 3.61QSTVGASGVYY701 pKa = 9.17PSFMSRR707 pKa = 11.84IVYY710 pKa = 9.0KK711 pKa = 10.2HH712 pKa = 4.97YY713 pKa = 10.44RR714 pKa = 11.84SLISEE719 pKa = 4.08VTTCFFLFEE728 pKa = 4.93KK729 pKa = 10.54GLHH732 pKa = 5.82GNMNEE737 pKa = 3.92EE738 pKa = 4.11AKK740 pKa = 10.28IHH742 pKa = 6.37LEE744 pKa = 4.09TVEE747 pKa = 3.88WALKK751 pKa = 10.02FRR753 pKa = 11.84EE754 pKa = 4.15KK755 pKa = 10.57EE756 pKa = 3.94EE757 pKa = 4.4KK758 pKa = 10.33YY759 pKa = 10.99GEE761 pKa = 4.22SLVEE765 pKa = 3.82NGYY768 pKa = 8.95MMWEE772 pKa = 3.79LRR774 pKa = 11.84EE775 pKa = 3.97NAEE778 pKa = 4.25LAEE781 pKa = 4.0QQLYY785 pKa = 9.59CQDD788 pKa = 4.51AIEE791 pKa = 4.33LAAIEE796 pKa = 4.29LNKK799 pKa = 10.08VLATKK804 pKa = 10.79SNVVANSILSKK815 pKa = 10.54NWEE818 pKa = 4.13EE819 pKa = 4.57PYY821 pKa = 10.49FSQTRR826 pKa = 11.84NISLKK831 pKa = 10.41GMSGQVQEE839 pKa = 5.26DD840 pKa = 3.94GHH842 pKa = 7.67LSSSVTIIEE851 pKa = 4.86AIRR854 pKa = 11.84YY855 pKa = 7.89LSNSRR860 pKa = 11.84HH861 pKa = 5.45NPSLLKK867 pKa = 10.55LYY869 pKa = 10.81EE870 pKa = 3.89EE871 pKa = 4.35TRR873 pKa = 11.84EE874 pKa = 4.01QKK876 pKa = 10.87AMARR880 pKa = 11.84IVRR883 pKa = 11.84KK884 pKa = 7.56YY885 pKa = 10.4QRR887 pKa = 11.84TEE889 pKa = 3.26ADD891 pKa = 2.82RR892 pKa = 11.84GFFITTLPTRR902 pKa = 11.84CRR904 pKa = 11.84LEE906 pKa = 4.86IIEE909 pKa = 5.2DD910 pKa = 4.13YY911 pKa = 11.28YY912 pKa = 11.65DD913 pKa = 5.51AIAKK917 pKa = 9.57NISEE921 pKa = 4.61EE922 pKa = 4.25YY923 pKa = 9.9ISYY926 pKa = 10.67GGEE929 pKa = 3.95KK930 pKa = 9.97KK931 pKa = 10.25ILAIQGALEE940 pKa = 4.05KK941 pKa = 10.58ALRR944 pKa = 11.84WASGEE949 pKa = 4.18SFIEE953 pKa = 4.03LSNHH957 pKa = 5.04KK958 pKa = 9.82FIRR961 pKa = 11.84MKK963 pKa = 10.47RR964 pKa = 11.84KK965 pKa = 9.85LMYY968 pKa = 10.45VSADD972 pKa = 3.22ATKK975 pKa = 9.98WSPGDD980 pKa = 3.31NSAKK984 pKa = 9.7FRR986 pKa = 11.84RR987 pKa = 11.84FTSMLHH993 pKa = 6.44NGLPNNKK1000 pKa = 9.38LKK1002 pKa = 11.14NCVIDD1007 pKa = 4.3ALKK1010 pKa = 10.29QVYY1013 pKa = 7.98KK1014 pKa = 10.5TDD1016 pKa = 3.68FFMSRR1021 pKa = 11.84KK1022 pKa = 8.29LRR1024 pKa = 11.84NYY1026 pKa = 8.26IDD1028 pKa = 3.59SMEE1031 pKa = 4.42SLDD1034 pKa = 3.65PHH1036 pKa = 6.9IKK1038 pKa = 10.12QFLDD1042 pKa = 4.07FFPDD1046 pKa = 3.3GHH1048 pKa = 7.68HH1049 pKa = 7.06GEE1051 pKa = 4.57VKK1053 pKa = 10.85GNWLQGNLNKK1063 pKa = 10.24CSSLFGVAMSLLFKK1077 pKa = 9.92QVWMNLFPEE1086 pKa = 4.75LDD1088 pKa = 3.76CFFEE1092 pKa = 4.59FAHH1095 pKa = 6.73HH1096 pKa = 6.98SDD1098 pKa = 3.78DD1099 pKa = 3.8ALFIYY1104 pKa = 9.85GYY1106 pKa = 10.29LEE1108 pKa = 4.32PVDD1111 pKa = 6.0DD1112 pKa = 4.32GTDD1115 pKa = 2.66WFLFVSQQIQAGHH1128 pKa = 5.66LHH1130 pKa = 6.18WFSVNTEE1137 pKa = 3.46MWKK1140 pKa = 10.93SMFNLHH1146 pKa = 5.5EE1147 pKa = 5.42HH1148 pKa = 6.37ILLLGSIKK1156 pKa = 10.17ISPKK1160 pKa = 8.91KK1161 pKa = 7.32TTVSPTNAEE1170 pKa = 3.94FLSTFFEE1177 pKa = 4.95GCAVSIPFVKK1187 pKa = 10.18ILLGSLSDD1195 pKa = 4.29LPGLGYY1201 pKa = 10.41FDD1203 pKa = 5.73DD1204 pKa = 4.57LAAAQSRR1211 pKa = 11.84CVKK1214 pKa = 10.58ALDD1217 pKa = 4.55LGASPQVAQLAVALCTSKK1235 pKa = 10.93VEE1237 pKa = 4.21RR1238 pKa = 11.84LYY1240 pKa = 10.3GTAPGMVNHH1249 pKa = 6.53PTAYY1253 pKa = 10.36LQVKK1257 pKa = 9.15HH1258 pKa = 7.03ADD1260 pKa = 3.47TPIPLGGNGAMSIMEE1275 pKa = 4.97LATAGIGMSDD1285 pKa = 3.26KK1286 pKa = 11.13NLLKK1290 pKa = 10.47RR1291 pKa = 11.84ALLGYY1296 pKa = 7.24SHH1298 pKa = 7.19KK1299 pKa = 10.13RR1300 pKa = 11.84QKK1302 pKa = 11.31SMLYY1306 pKa = 9.84ILGLFKK1312 pKa = 10.83FLMKK1316 pKa = 10.83LSDD1319 pKa = 3.16EE1320 pKa = 4.57TFQHH1324 pKa = 5.74EE1325 pKa = 4.32RR1326 pKa = 11.84LGQFSFIGKK1335 pKa = 6.9VQWKK1339 pKa = 9.55IFTPKK1344 pKa = 10.37SEE1346 pKa = 4.34FEE1348 pKa = 4.04FADD1351 pKa = 3.67MYY1353 pKa = 10.26TSKK1356 pKa = 10.59FLEE1359 pKa = 4.51LWSSQHH1365 pKa = 4.32VTYY1368 pKa = 10.52DD1369 pKa = 3.26YY1370 pKa = 10.53IIPKK1374 pKa = 10.24GRR1376 pKa = 11.84DD1377 pKa = 2.99NLLIYY1382 pKa = 10.13LVRR1385 pKa = 11.84KK1386 pKa = 10.09LNDD1389 pKa = 3.67PSIVTAMTMQSPLQLRR1405 pKa = 11.84FRR1407 pKa = 11.84MQAKK1411 pKa = 8.76QHH1413 pKa = 5.53MKK1415 pKa = 9.57VCRR1418 pKa = 11.84LDD1420 pKa = 4.19GEE1422 pKa = 4.52WVTFRR1427 pKa = 11.84EE1428 pKa = 4.22VLAAANSFAEE1438 pKa = 4.48NYY1440 pKa = 9.69SATSQDD1446 pKa = 2.27IDD1448 pKa = 3.96LFQTLTSCTFSKK1460 pKa = 10.52EE1461 pKa = 4.09YY1462 pKa = 10.24AWKK1465 pKa = 10.51DD1466 pKa = 3.45FLNGIHH1472 pKa = 7.14CDD1474 pKa = 3.81VIPTKK1479 pKa = 10.13QVQRR1483 pKa = 11.84AKK1485 pKa = 10.05VARR1488 pKa = 11.84TFTVRR1493 pKa = 11.84EE1494 pKa = 3.88KK1495 pKa = 11.21DD1496 pKa = 3.43QIIQNSIPAVIGYY1509 pKa = 9.08KK1510 pKa = 10.11FAVTVEE1516 pKa = 4.08EE1517 pKa = 4.3MSDD1520 pKa = 3.48VLDD1523 pKa = 3.63TAKK1526 pKa = 10.65FPDD1529 pKa = 4.16SLSVDD1534 pKa = 4.21LKK1536 pKa = 9.19TMKK1539 pKa = 10.63DD1540 pKa = 3.23GVYY1543 pKa = 10.04RR1544 pKa = 11.84EE1545 pKa = 4.51LGLDD1549 pKa = 3.05ISLPDD1554 pKa = 3.36VMKK1557 pKa = 10.82RR1558 pKa = 11.84IAPMLYY1564 pKa = 9.17KK1565 pKa = 10.23SSKK1568 pKa = 8.05SRR1570 pKa = 11.84VVIVQGNVEE1579 pKa = 4.13GTAEE1583 pKa = 4.67AICAYY1588 pKa = 8.26WLKK1591 pKa = 11.25SMSLVKK1597 pKa = 9.78TIRR1600 pKa = 11.84VKK1602 pKa = 9.68PHH1604 pKa = 6.57KK1605 pKa = 9.88EE1606 pKa = 3.45VLQAVSIFNRR1616 pKa = 11.84KK1617 pKa = 7.93EE1618 pKa = 4.28DD1619 pKa = 3.16IGQQKK1624 pKa = 10.37DD1625 pKa = 3.17LAALKK1630 pKa = 10.62LCIEE1634 pKa = 4.11VWRR1637 pKa = 11.84WCKK1640 pKa = 10.77ANSAPYY1646 pKa = 9.96RR1647 pKa = 11.84DD1648 pKa = 3.65WFQALWFEE1656 pKa = 5.06DD1657 pKa = 3.4KK1658 pKa = 10.81TFSEE1662 pKa = 4.22WLDD1665 pKa = 3.35RR1666 pKa = 11.84FCRR1669 pKa = 11.84VGVPPIDD1676 pKa = 5.05PEE1678 pKa = 4.22IQCAALMIADD1688 pKa = 3.8IKK1690 pKa = 11.15GDD1692 pKa = 3.68YY1693 pKa = 10.56SVLQLQANRR1702 pKa = 11.84RR1703 pKa = 11.84AYY1705 pKa = 10.45SGKK1708 pKa = 10.2QYY1710 pKa = 11.06DD1711 pKa = 4.14AYY1713 pKa = 10.92CVQTYY1718 pKa = 11.07NEE1720 pKa = 4.09VTKK1723 pKa = 10.65LYY1725 pKa = 10.64EE1726 pKa = 4.4GDD1728 pKa = 3.59LRR1730 pKa = 11.84VTFNFGLDD1738 pKa = 3.54CARR1741 pKa = 11.84LEE1743 pKa = 4.27IFWDD1747 pKa = 3.34KK1748 pKa = 10.73KK1749 pKa = 11.04AYY1751 pKa = 9.56ILEE1754 pKa = 4.09TSITQKK1760 pKa = 10.62HH1761 pKa = 5.13VLKK1764 pKa = 10.89IMMDD1768 pKa = 3.68EE1769 pKa = 4.17VSKK1772 pKa = 10.92EE1773 pKa = 3.94LIKK1776 pKa = 10.98CGMRR1780 pKa = 11.84FNTEE1784 pKa = 3.34QVQGVRR1790 pKa = 11.84HH1791 pKa = 5.07MVLFKK1796 pKa = 10.71TEE1798 pKa = 4.78SGFEE1802 pKa = 3.75WGKK1805 pKa = 10.08PNIPCIVYY1813 pKa = 9.82KK1814 pKa = 10.86NCVLRR1819 pKa = 11.84TSLRR1823 pKa = 11.84TTQAINHH1830 pKa = 6.46KK1831 pKa = 10.51FMITIKK1837 pKa = 10.7DD1838 pKa = 3.46DD1839 pKa = 3.55GLRR1842 pKa = 11.84AIAQHH1847 pKa = 7.03DD1848 pKa = 3.81EE1849 pKa = 4.0DD1850 pKa = 4.32SPRR1853 pKa = 11.84FLLAHH1858 pKa = 7.1AFHH1861 pKa = 7.64TIRR1864 pKa = 11.84DD1865 pKa = 3.37IRR1867 pKa = 11.84YY1868 pKa = 7.63QAVDD1872 pKa = 3.11AVSNVWFIHH1881 pKa = 6.02KK1882 pKa = 9.84GVKK1885 pKa = 10.09LYY1887 pKa = 10.75LNPIISSGLLEE1898 pKa = 4.71NFMKK1902 pKa = 10.52NLPAAIPPAAYY1913 pKa = 10.39SLIMNRR1919 pKa = 11.84AKK1921 pKa = 10.51ISVDD1925 pKa = 2.8LFMFNDD1931 pKa = 3.98LLKK1934 pKa = 10.95LINPRR1939 pKa = 11.84NTLDD1943 pKa = 3.72LSGLEE1948 pKa = 4.11TTGDD1952 pKa = 3.62GFSTVSSMSSRR1963 pKa = 11.84LWSEE1967 pKa = 3.82EE1968 pKa = 3.52MSLVDD1973 pKa = 6.06DD1974 pKa = 5.81DD1975 pKa = 5.74EE1976 pKa = 4.84EE1977 pKa = 6.37LDD1979 pKa = 4.68DD1980 pKa = 5.51EE1981 pKa = 4.7FTIDD1985 pKa = 3.69LQDD1988 pKa = 3.14VDD1990 pKa = 5.18FEE1992 pKa = 4.98NIDD1995 pKa = 3.42MEE1997 pKa = 5.29ADD1999 pKa = 3.24IEE2001 pKa = 4.9HH2002 pKa = 6.99FLQDD2006 pKa = 3.38EE2007 pKa = 4.25SSYY2010 pKa = 11.22TGDD2013 pKa = 3.77LLISTEE2019 pKa = 4.03EE2020 pKa = 4.29TEE2022 pKa = 4.42SKK2024 pKa = 10.57KK2025 pKa = 10.03MRR2027 pKa = 11.84GIMKK2031 pKa = 9.41ILEE2034 pKa = 4.27PVRR2037 pKa = 11.84LIKK2040 pKa = 10.58SWVSRR2045 pKa = 11.84GLSIEE2050 pKa = 4.22KK2051 pKa = 10.23VYY2053 pKa = 11.34SPVNIILMSRR2063 pKa = 11.84YY2064 pKa = 9.17ISKK2067 pKa = 8.81TFNLSTKK2074 pKa = 9.47QVSLLDD2080 pKa = 4.49PYY2082 pKa = 11.58DD2083 pKa = 3.72LTEE2086 pKa = 4.47LEE2088 pKa = 4.57SIVRR2092 pKa = 11.84GWGEE2096 pKa = 3.81CVIDD2100 pKa = 3.86QFEE2103 pKa = 4.18NLDD2106 pKa = 3.73RR2107 pKa = 11.84EE2108 pKa = 4.57AQSMVVNKK2116 pKa = 8.78GICPEE2121 pKa = 4.0DD2122 pKa = 4.04VIPDD2126 pKa = 3.55SLFSFRR2132 pKa = 11.84HH2133 pKa = 4.42TMVLLRR2139 pKa = 11.84RR2140 pKa = 11.84LFPQDD2145 pKa = 4.03SISSFYY2151 pKa = 11.41

Molecular weight: 246.46 kDa
Isoelectric point according different methods:

Try ESI

ChTry ESI

ArgC ESI

LysN ESI

TryLysC ESI

Try MALDI

ChTry MALDI

ArgC MALDI

LysN MALDI

TryLysC MALDI

Try LTQ

ChTry LTQ

ArgC LTQ

LysN LTQ

TryLysC LTQ

Try MSlow

ChTry MSlow

ArgC MSlow

LysN MSlow

TryLysC MSlow

Try MShigh

ChTry MShigh

ArgC MShigh

LysN MShigh

TryLysC MShigh

For dipeptide frequency statistics click here

Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here