Amino acid dipepetide frequency for Pseudopedobacter saltans (strain ATCC 51119 / DSM 12145 / JCM 21818 / LMG 10337 / NBRC 100064 / NCIMB 13643) (Pedobacter saltans)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.549AlaAla: 4.549 ± 0.066
0.58AlaCys: 0.58 ± 0.02
3.679AlaAsp: 3.679 ± 0.064
4.195AlaGlu: 4.195 ± 0.064
3.308AlaPhe: 3.308 ± 0.056
4.789AlaGly: 4.789 ± 0.072
1.096AlaHis: 1.096 ± 0.031
5.308AlaIle: 5.308 ± 0.062
4.96AlaLys: 4.96 ± 0.066
6.371AlaLeu: 6.371 ± 0.078
1.43AlaMet: 1.43 ± 0.036
3.917AlaAsn: 3.917 ± 0.057
1.973AlaPro: 1.973 ± 0.042
2.403AlaGln: 2.403 ± 0.049
2.097AlaArg: 2.097 ± 0.041
4.325AlaSer: 4.325 ± 0.065
3.601AlaThr: 3.601 ± 0.076
4.263AlaVal: 4.263 ± 0.048
0.709AlaTrp: 0.709 ± 0.023
2.811AlaTyr: 2.811 ± 0.047
0.0AlaXaa: 0.0 ± 0.0
Cys
0.457CysAla: 0.457 ± 0.019
0.122CysCys: 0.122 ± 0.009
0.393CysAsp: 0.393 ± 0.018
0.403CysGlu: 0.403 ± 0.017
0.415CysPhe: 0.415 ± 0.019
0.594CysGly: 0.594 ± 0.022
0.158CysHis: 0.158 ± 0.012
0.604CysIle: 0.604 ± 0.021
0.545CysLys: 0.545 ± 0.02
0.692CysLeu: 0.692 ± 0.024
0.155CysMet: 0.155 ± 0.012
0.418CysAsn: 0.418 ± 0.016
0.312CysPro: 0.312 ± 0.016
0.219CysGln: 0.219 ± 0.015
0.274CysArg: 0.274 ± 0.015
0.541CysSer: 0.541 ± 0.02
0.387CysThr: 0.387 ± 0.016
0.441CysVal: 0.441 ± 0.019
0.077CysTrp: 0.077 ± 0.008
0.308CysTyr: 0.308 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
3.489AspAla: 3.489 ± 0.055
0.374AspCys: 0.374 ± 0.019
2.471AspAsp: 2.471 ± 0.073
3.358AspGlu: 3.358 ± 0.056
3.404AspPhe: 3.404 ± 0.059
3.86AspGly: 3.86 ± 0.059
0.861AspHis: 0.861 ± 0.024
4.595AspIle: 4.595 ± 0.064
4.399AspLys: 4.399 ± 0.066
5.287AspLeu: 5.287 ± 0.06
1.057AspMet: 1.057 ± 0.024
3.185AspAsn: 3.185 ± 0.058
1.869AspPro: 1.869 ± 0.041
1.615AspGln: 1.615 ± 0.03
2.12AspArg: 2.12 ± 0.041
2.939AspSer: 2.939 ± 0.053
2.39AspThr: 2.39 ± 0.047
3.375AspVal: 3.375 ± 0.055
0.76AspTrp: 0.76 ± 0.029
2.692AspTyr: 2.692 ± 0.059
0.0AspXaa: 0.0 ± 0.0
Glu
4.076GluAla: 4.076 ± 0.071
0.341GluCys: 0.341 ± 0.017
3.125GluAsp: 3.125 ± 0.054
4.4GluGlu: 4.4 ± 0.08
2.601GluPhe: 2.601 ± 0.04
3.722GluGly: 3.722 ± 0.065
1.006GluHis: 1.006 ± 0.027
5.149GluIle: 5.149 ± 0.076
5.548GluLys: 5.548 ± 0.069
5.743GluLeu: 5.743 ± 0.078
1.391GluMet: 1.391 ± 0.031
4.179GluAsn: 4.179 ± 0.059
1.57GluPro: 1.57 ± 0.035
2.317GluGln: 2.317 ± 0.04
2.593GluArg: 2.593 ± 0.048
3.303GluSer: 3.303 ± 0.047
3.179GluThr: 3.179 ± 0.056
3.926GluVal: 3.926 ± 0.06
0.67GluTrp: 0.67 ± 0.021
2.301GluTyr: 2.301 ± 0.042
0.0GluXaa: 0.0 ± 0.0
Phe
3.146PheAla: 3.146 ± 0.051
0.446PheCys: 0.446 ± 0.02
3.134PheAsp: 3.134 ± 0.048
2.868PheGlu: 2.868 ± 0.054
2.676PhePhe: 2.676 ± 0.054
3.473PheGly: 3.473 ± 0.057
0.781PheHis: 0.781 ± 0.022
3.791PheIle: 3.791 ± 0.054
3.658PheLys: 3.658 ± 0.059
4.558PheLeu: 4.558 ± 0.065
1.054PheMet: 1.054 ± 0.028
3.232PheAsn: 3.232 ± 0.055
1.701PhePro: 1.701 ± 0.035
1.397PheGln: 1.397 ± 0.034
1.858PheArg: 1.858 ± 0.043
4.02PheSer: 4.02 ± 0.056
2.816PheThr: 2.816 ± 0.056
3.051PheVal: 3.051 ± 0.046
0.582PheTrp: 0.582 ± 0.024
2.266PheTyr: 2.266 ± 0.044
0.0PheXaa: 0.0 ± 0.0
Gly
4.364GlyAla: 4.364 ± 0.069
0.551GlyCys: 0.551 ± 0.02
3.41GlyAsp: 3.41 ± 0.068
3.614GlyGlu: 3.614 ± 0.06
3.611GlyPhe: 3.611 ± 0.05
4.801GlyGly: 4.801 ± 0.077
1.145GlyHis: 1.145 ± 0.031
5.698GlyIle: 5.698 ± 0.076
5.581GlyLys: 5.581 ± 0.078
6.047GlyLeu: 6.047 ± 0.075
1.54GlyMet: 1.54 ± 0.037
4.114GlyAsn: 4.114 ± 0.066
1.467GlyPro: 1.467 ± 0.039
2.012GlyGln: 2.012 ± 0.043
2.454GlyArg: 2.454 ± 0.048
4.293GlySer: 4.293 ± 0.063
4.207GlyThr: 4.207 ± 0.09
4.39GlyVal: 4.39 ± 0.057
0.869GlyTrp: 0.869 ± 0.025
3.173GlyTyr: 3.173 ± 0.052
0.0GlyXaa: 0.0 ± 0.0
His
1.0HisAla: 1.0 ± 0.028
0.183HisCys: 0.183 ± 0.012
0.776HisAsp: 0.776 ± 0.023
0.87HisGlu: 0.87 ± 0.027
1.059HisPhe: 1.059 ± 0.028
1.062HisGly: 1.062 ± 0.029
0.503HisHis: 0.503 ± 0.024
1.429HisIle: 1.429 ± 0.04
1.087HisLys: 1.087 ± 0.026
1.729HisLeu: 1.729 ± 0.034
0.338HisMet: 0.338 ± 0.017
0.926HisAsn: 0.926 ± 0.025
0.835HisPro: 0.835 ± 0.025
0.739HisGln: 0.739 ± 0.025
0.673HisArg: 0.673 ± 0.025
1.057HisSer: 1.057 ± 0.031
0.888HisThr: 0.888 ± 0.026
0.928HisVal: 0.928 ± 0.026
0.225HisTrp: 0.225 ± 0.014
0.791HisTyr: 0.791 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
5.712IleAla: 5.712 ± 0.069
0.743IleCys: 0.743 ± 0.027
4.7IleAsp: 4.7 ± 0.064
4.855IleGlu: 4.855 ± 0.068
3.417IlePhe: 3.417 ± 0.056
5.14IleGly: 5.14 ± 0.079
1.304IleHis: 1.304 ± 0.031
5.871IleIle: 5.871 ± 0.088
5.952IleLys: 5.952 ± 0.071
6.903IleLeu: 6.903 ± 0.089
1.353IleMet: 1.353 ± 0.035
4.804IleAsn: 4.804 ± 0.064
3.183IlePro: 3.183 ± 0.049
2.459IleGln: 2.459 ± 0.047
2.947IleArg: 2.947 ± 0.051
5.844IleSer: 5.844 ± 0.079
4.385IleThr: 4.385 ± 0.081
4.645IleVal: 4.645 ± 0.063
0.808IleTrp: 0.808 ± 0.025
3.062IleTyr: 3.062 ± 0.053
0.0IleXaa: 0.0 ± 0.0
Lys
5.196LysAla: 5.196 ± 0.07
0.35LysCys: 0.35 ± 0.016
4.727LysAsp: 4.727 ± 0.066
5.907LysGlu: 5.907 ± 0.085
2.988LysPhe: 2.988 ± 0.043
5.055LysGly: 5.055 ± 0.067
1.338LysHis: 1.338 ± 0.032
5.996LysIle: 5.996 ± 0.076
6.25LysLys: 6.25 ± 0.084
6.568LysLeu: 6.568 ± 0.074
1.837LysMet: 1.837 ± 0.036
5.221LysAsn: 5.221 ± 0.075
2.725LysPro: 2.725 ± 0.039
2.874LysGln: 2.874 ± 0.052
2.992LysArg: 2.992 ± 0.053
4.815LysSer: 4.815 ± 0.059
4.293LysThr: 4.293 ± 0.054
4.913LysVal: 4.913 ± 0.058
0.895LysTrp: 0.895 ± 0.026
3.303LysTyr: 3.303 ± 0.054
0.0LysXaa: 0.0 ± 0.0
Leu
6.105LeuAla: 6.105 ± 0.075
0.725LeuCys: 0.725 ± 0.025
4.971LeuAsp: 4.971 ± 0.07
5.433LeuGlu: 5.433 ± 0.081
4.648LeuPhe: 4.648 ± 0.077
5.79LeuGly: 5.79 ± 0.077
1.563LeuHis: 1.563 ± 0.039
6.844LeuIle: 6.844 ± 0.087
7.901LeuLys: 7.901 ± 0.087
8.78LeuLeu: 8.78 ± 0.11
2.033LeuMet: 2.033 ± 0.046
6.006LeuAsn: 6.006 ± 0.083
3.739LeuPro: 3.739 ± 0.053
3.129LeuGln: 3.129 ± 0.052
3.448LeuArg: 3.448 ± 0.053
7.197LeuSer: 7.197 ± 0.077
5.098LeuThr: 5.098 ± 0.07
5.175LeuVal: 5.175 ± 0.07
0.915LeuTrp: 0.915 ± 0.029
3.422LeuTyr: 3.422 ± 0.051
0.0LeuXaa: 0.0 ± 0.0
Met
1.554MetAla: 1.554 ± 0.032
0.146MetCys: 0.146 ± 0.01
1.118MetAsp: 1.118 ± 0.026
1.243MetGlu: 1.243 ± 0.028
0.866MetPhe: 0.866 ± 0.025
1.408MetGly: 1.408 ± 0.038
0.362MetHis: 0.362 ± 0.018
1.39MetIle: 1.39 ± 0.03
1.98MetLys: 1.98 ± 0.038
1.909MetLeu: 1.909 ± 0.041
0.549MetMet: 0.549 ± 0.023
1.202MetAsn: 1.202 ± 0.031
0.859MetPro: 0.859 ± 0.025
0.765MetGln: 0.765 ± 0.024
0.889MetArg: 0.889 ± 0.023
1.346MetSer: 1.346 ± 0.033
0.987MetThr: 0.987 ± 0.029
1.284MetVal: 1.284 ± 0.037
0.177MetTrp: 0.177 ± 0.012
0.655MetTyr: 0.655 ± 0.024
0.0MetXaa: 0.0 ± 0.0
Asn
3.928AsnAla: 3.928 ± 0.059
0.445AsnCys: 0.445 ± 0.021
2.984AsnAsp: 2.984 ± 0.056
3.283AsnGlu: 3.283 ± 0.051
2.924AsnPhe: 2.924 ± 0.056
4.426AsnGly: 4.426 ± 0.077
1.067AsnHis: 1.067 ± 0.028
5.14AsnIle: 5.14 ± 0.065
4.589AsnLys: 4.589 ± 0.059
5.65AsnLeu: 5.65 ± 0.071
1.217AsnMet: 1.217 ± 0.03
3.941AsnAsn: 3.941 ± 0.07
2.834AsnPro: 2.834 ± 0.051
2.306AsnGln: 2.306 ± 0.043
2.517AsnArg: 2.517 ± 0.041
3.923AsnSer: 3.923 ± 0.061
3.531AsnThr: 3.531 ± 0.066
3.572AsnVal: 3.572 ± 0.069
0.873AsnTrp: 0.873 ± 0.03
2.957AsnTyr: 2.957 ± 0.05
0.0AsnXaa: 0.0 ± 0.0
Pro
2.396ProAla: 2.396 ± 0.046
0.201ProCys: 0.201 ± 0.013
2.211ProAsp: 2.211 ± 0.042
2.77ProGlu: 2.77 ± 0.046
1.887ProPhe: 1.887 ± 0.033
2.26ProGly: 2.26 ± 0.041
0.65ProHis: 0.65 ± 0.027
2.562ProIle: 2.562 ± 0.043
2.472ProLys: 2.472 ± 0.046
3.163ProLeu: 3.163 ± 0.044
0.661ProMet: 0.661 ± 0.022
2.133ProAsn: 2.133 ± 0.038
0.797ProPro: 0.797 ± 0.03
1.271ProGln: 1.271 ± 0.033
1.024ProArg: 1.024 ± 0.027
2.232ProSer: 2.232 ± 0.036
1.845ProThr: 1.845 ± 0.04
2.661ProVal: 2.661 ± 0.045
0.401ProTrp: 0.401 ± 0.017
1.517ProTyr: 1.517 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
2.26GlnAla: 2.26 ± 0.044
0.15GlnCys: 0.15 ± 0.011
1.664GlnAsp: 1.664 ± 0.034
2.238GlnGlu: 2.238 ± 0.043
1.572GlnPhe: 1.572 ± 0.033
1.918GlnGly: 1.918 ± 0.041
0.686GlnHis: 0.686 ± 0.023
2.686GlnIle: 2.686 ± 0.043
2.855GlnLys: 2.855 ± 0.048
3.346GlnLeu: 3.346 ± 0.063
0.75GlnMet: 0.75 ± 0.027
2.202GlnAsn: 2.202 ± 0.042
1.12GlnPro: 1.12 ± 0.027
1.534GlnGln: 1.534 ± 0.037
1.353GlnArg: 1.353 ± 0.031
2.033GlnSer: 2.033 ± 0.041
1.957GlnThr: 1.957 ± 0.037
1.961GlnVal: 1.961 ± 0.04
0.374GlnTrp: 0.374 ± 0.018
1.416GlnTyr: 1.416 ± 0.036
0.0GlnXaa: 0.0 ± 0.0
Arg
2.169ArgAla: 2.169 ± 0.049
0.212ArgCys: 0.212 ± 0.013
1.906ArgAsp: 1.906 ± 0.037
2.341ArgGlu: 2.341 ± 0.046
2.047ArgPhe: 2.047 ± 0.04
2.227ArgGly: 2.227 ± 0.045
0.631ArgHis: 0.631 ± 0.022
3.154ArgIle: 3.154 ± 0.037
2.984ArgLys: 2.984 ± 0.045
3.596ArgLeu: 3.596 ± 0.056
0.89ArgMet: 0.89 ± 0.025
2.398ArgAsn: 2.398 ± 0.046
1.235ArgPro: 1.235 ± 0.035
1.257ArgGln: 1.257 ± 0.035
1.47ArgArg: 1.47 ± 0.037
2.186ArgSer: 2.186 ± 0.043
2.073ArgThr: 2.073 ± 0.042
2.236ArgVal: 2.236 ± 0.038
0.498ArgTrp: 0.498 ± 0.018
1.794ArgTyr: 1.794 ± 0.034
0.0ArgXaa: 0.0 ± 0.0
Ser
4.314SerAla: 4.314 ± 0.067
0.615SerCys: 0.615 ± 0.023
3.353SerAsp: 3.353 ± 0.053
3.716SerGlu: 3.716 ± 0.049
3.898SerPhe: 3.898 ± 0.053
5.097SerGly: 5.097 ± 0.081
1.076SerHis: 1.076 ± 0.03
5.13SerIle: 5.13 ± 0.071
4.81SerLys: 4.81 ± 0.06
6.647SerLeu: 6.647 ± 0.088
1.205SerMet: 1.205 ± 0.03
3.863SerAsn: 3.863 ± 0.068
2.329SerPro: 2.329 ± 0.044
2.078SerGln: 2.078 ± 0.038
2.387SerArg: 2.387 ± 0.046
4.679SerSer: 4.679 ± 0.069
3.507SerThr: 3.507 ± 0.064
4.209SerVal: 4.209 ± 0.062
0.747SerTrp: 0.747 ± 0.027
2.989SerTyr: 2.989 ± 0.05
0.0SerXaa: 0.0 ± 0.0
Thr
4.043ThrAla: 4.043 ± 0.11
0.333ThrCys: 0.333 ± 0.015
3.077ThrAsp: 3.077 ± 0.054
3.153ThrGlu: 3.153 ± 0.049
2.854ThrPhe: 2.854 ± 0.055
4.299ThrGly: 4.299 ± 0.065
0.873ThrHis: 0.873 ± 0.023
4.355ThrIle: 4.355 ± 0.072
3.635ThrLys: 3.635 ± 0.054
5.111ThrLeu: 5.111 ± 0.073
0.881ThrMet: 0.881 ± 0.028
3.01ThrAsn: 3.01 ± 0.055
2.339ThrPro: 2.339 ± 0.046
1.671ThrGln: 1.671 ± 0.035
1.696ThrArg: 1.696 ± 0.033
3.599ThrSer: 3.599 ± 0.061
3.027ThrThr: 3.027 ± 0.067
3.774ThrVal: 3.774 ± 0.09
0.594ThrTrp: 0.594 ± 0.022
2.313ThrTyr: 2.313 ± 0.052
0.0ThrXaa: 0.0 ± 0.0
Val
4.16ValAla: 4.16 ± 0.061
0.539ValCys: 0.539 ± 0.02
3.378ValAsp: 3.378 ± 0.057
3.575ValGlu: 3.575 ± 0.053
3.343ValPhe: 3.343 ± 0.05
3.748ValGly: 3.748 ± 0.061
0.929ValHis: 0.929 ± 0.027
4.714ValIle: 4.714 ± 0.066
4.878ValLys: 4.878 ± 0.068
5.798ValLeu: 5.798 ± 0.071
1.245ValMet: 1.245 ± 0.03
3.804ValAsn: 3.804 ± 0.061
2.223ValPro: 2.223 ± 0.04
1.812ValGln: 1.812 ± 0.037
2.236ValArg: 2.236 ± 0.041
4.619ValSer: 4.619 ± 0.073
3.379ValThr: 3.379 ± 0.069
4.035ValVal: 4.035 ± 0.07
0.692ValTrp: 0.692 ± 0.024
2.611ValTyr: 2.611 ± 0.052
0.0ValXaa: 0.0 ± 0.0
Trp
0.741TrpAla: 0.741 ± 0.027
0.107TrpCys: 0.107 ± 0.009
0.679TrpAsp: 0.679 ± 0.023
0.704TrpGlu: 0.704 ± 0.023
0.599TrpPhe: 0.599 ± 0.021
0.808TrpGly: 0.808 ± 0.025
0.224TrpHis: 0.224 ± 0.014
0.816TrpIle: 0.816 ± 0.029
0.914TrpLys: 0.914 ± 0.025
1.046TrpLeu: 1.046 ± 0.03
0.317TrpMet: 0.317 ± 0.017
0.772TrpAsn: 0.772 ± 0.024
0.341TrpPro: 0.341 ± 0.017
0.455TrpGln: 0.455 ± 0.018
0.495TrpArg: 0.495 ± 0.018
0.675TrpSer: 0.675 ± 0.023
0.633TrpThr: 0.633 ± 0.023
0.652TrpVal: 0.652 ± 0.022
0.168TrpTrp: 0.168 ± 0.01
0.45TrpTyr: 0.45 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.708TyrAla: 2.708 ± 0.05
0.354TyrCys: 0.354 ± 0.019
2.344TyrAsp: 2.344 ± 0.044
2.214TyrGlu: 2.214 ± 0.041
2.39TyrPhe: 2.39 ± 0.045
2.862TyrGly: 2.862 ± 0.057
0.846TyrHis: 0.846 ± 0.027
2.857TyrIle: 2.857 ± 0.046
3.245TyrLys: 3.245 ± 0.05
3.98TyrLeu: 3.98 ± 0.058
0.787TyrMet: 0.787 ± 0.022
2.78TyrAsn: 2.78 ± 0.048
1.663TyrPro: 1.663 ± 0.038
1.762TyrGln: 1.762 ± 0.036
1.781TyrArg: 1.781 ± 0.036
3.021TyrSer: 3.021 ± 0.05
2.453TyrThr: 2.453 ± 0.055
2.225TyrVal: 2.225 ± 0.043
0.557TyrTrp: 0.557 ± 0.019
1.963TyrTyr: 1.963 ± 0.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3780 proteins (1370524 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski