Amino acid dipepetide frequency for Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces naganishii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.462AlaAla: 5.462 ± 0.074	0.727AlaCys: 0.727 ± 0.017	3.228AlaAsp: 3.228 ± 0.038	3.829AlaGlu: 3.829 ± 0.044	2.296AlaPhe: 2.296 ± 0.034	3.866AlaGly: 3.866 ± 0.051	1.287AlaHis: 1.287 ± 0.022	3.358AlaIle: 3.358 ± 0.039	4.082AlaLys: 4.082 ± 0.048	5.919AlaLeu: 5.919 ± 0.053	1.419AlaMet: 1.419 ± 0.024	3.082AlaAsn: 3.082 ± 0.037	2.83AlaPro: 2.83 ± 0.047	2.604AlaGln: 2.604 ± 0.037	3.032AlaArg: 3.032 ± 0.04	5.131AlaSer: 5.131 ± 0.078	4.228AlaThr: 4.228 ± 0.046	4.327AlaVal: 4.327 ± 0.046	0.54AlaTrp: 0.54 ± 0.014	1.638AlaTyr: 1.638 ± 0.026	0.001AlaXaa: 0.001 ± 0.001
Cys	0.742CysAla: 0.742 ± 0.017	0.293CysCys: 0.293 ± 0.011	0.708CysAsp: 0.708 ± 0.016	0.6CysGlu: 0.6 ± 0.016	0.644CysPhe: 0.644 ± 0.018	0.89CysGly: 0.89 ± 0.022	0.331CysHis: 0.331 ± 0.011	0.887CysIle: 0.887 ± 0.019	0.712CysLys: 0.712 ± 0.018	1.316CysLeu: 1.316 ± 0.022	0.272CysMet: 0.272 ± 0.011	0.602CysAsn: 0.602 ± 0.014	0.55CysPro: 0.55 ± 0.016	0.49CysGln: 0.49 ± 0.014	0.573CysArg: 0.573 ± 0.016	1.051CysSer: 1.051 ± 0.022	0.676CysThr: 0.676 ± 0.017	0.88CysVal: 0.88 ± 0.02	0.162CysTrp: 0.162 ± 0.008	0.48CysTyr: 0.48 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.796AspAla: 3.796 ± 0.041	0.682AspCys: 0.682 ± 0.017	4.606AspAsp: 4.606 ± 0.073	4.775AspGlu: 4.775 ± 0.052	2.541AspPhe: 2.541 ± 0.033	3.367AspGly: 3.367 ± 0.041	1.156AspHis: 1.156 ± 0.02	3.83AspIle: 3.83 ± 0.043	3.395AspLys: 3.395 ± 0.041	5.468AspLeu: 5.468 ± 0.048	1.223AspMet: 1.223 ± 0.023	2.839AspAsn: 2.839 ± 0.031	2.708AspPro: 2.708 ± 0.034	1.878AspGln: 1.878 ± 0.028	2.453AspArg: 2.453 ± 0.032	4.694AspSer: 4.694 ± 0.049	3.529AspThr: 3.529 ± 0.04	3.82AspVal: 3.82 ± 0.042	0.619AspTrp: 0.619 ± 0.015	2.003AspTyr: 2.003 ± 0.025	0.001AspXaa: 0.001 ± 0.001
Glu	3.503GluAla: 3.503 ± 0.038	0.672GluCys: 0.672 ± 0.019	4.192GluAsp: 4.192 ± 0.052	5.678GluGlu: 5.678 ± 0.079	2.644GluPhe: 2.644 ± 0.034	3.03GluGly: 3.03 ± 0.037	1.386GluHis: 1.386 ± 0.023	3.643GluIle: 3.643 ± 0.041	4.593GluLys: 4.593 ± 0.056	6.606GluLeu: 6.606 ± 0.068	1.444GluMet: 1.444 ± 0.025	3.599GluAsn: 3.599 ± 0.048	2.196GluPro: 2.196 ± 0.039	3.017GluGln: 3.017 ± 0.032	3.439GluArg: 3.439 ± 0.038	4.666GluSer: 4.666 ± 0.05	3.968GluThr: 3.968 ± 0.039	3.594GluVal: 3.594 ± 0.038	0.668GluTrp: 0.668 ± 0.017	2.156GluTyr: 2.156 ± 0.03	0.002GluXaa: 0.002 ± 0.001
Phe	2.595PheAla: 2.595 ± 0.033	0.571PheCys: 0.571 ± 0.016	2.779PheAsp: 2.779 ± 0.036	2.674PheGlu: 2.674 ± 0.038	1.915PhePhe: 1.915 ± 0.032	2.64PheGly: 2.64 ± 0.044	1.017PheHis: 1.017 ± 0.023	2.501PheIle: 2.501 ± 0.033	2.802PheLys: 2.802 ± 0.036	3.969PheLeu: 3.969 ± 0.052	0.873PheMet: 0.873 ± 0.015	2.296PheAsn: 2.296 ± 0.034	1.871PhePro: 1.871 ± 0.027	1.877PheGln: 1.877 ± 0.027	1.689PheArg: 1.689 ± 0.028	3.23PheSer: 3.23 ± 0.04	2.407PheThr: 2.407 ± 0.031	2.787PheVal: 2.787 ± 0.036	0.507PheTrp: 0.507 ± 0.014	1.446PheTyr: 1.446 ± 0.027	0.002PheXaa: 0.002 ± 0.001
Gly	3.914GlyAla: 3.914 ± 0.064	0.787GlyCys: 0.787 ± 0.019	3.373GlyAsp: 3.373 ± 0.045	3.29GlyGlu: 3.29 ± 0.036	2.324GlyPhe: 2.324 ± 0.034	4.181GlyGly: 4.181 ± 0.072	1.293GlyHis: 1.293 ± 0.055	3.268GlyIle: 3.268 ± 0.038	3.851GlyLys: 3.851 ± 0.042	4.62GlyLeu: 4.62 ± 0.042	1.11GlyMet: 1.11 ± 0.023	2.978GlyAsn: 2.978 ± 0.039	2.155GlyPro: 2.155 ± 0.059	1.988GlyGln: 1.988 ± 0.031	2.577GlyArg: 2.577 ± 0.037	5.053GlySer: 5.053 ± 0.05	3.656GlyThr: 3.656 ± 0.041	3.695GlyVal: 3.695 ± 0.039	0.603GlyTrp: 0.603 ± 0.017	1.837GlyTyr: 1.837 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	1.19HisAla: 1.19 ± 0.024	0.361HisCys: 0.361 ± 0.012	1.191HisAsp: 1.191 ± 0.024	1.252HisGlu: 1.252 ± 0.021	0.987HisPhe: 0.987 ± 0.018	1.305HisGly: 1.305 ± 0.022	0.687HisHis: 0.687 ± 0.02	1.329HisIle: 1.329 ± 0.021	1.191HisLys: 1.191 ± 0.022	2.179HisLeu: 2.179 ± 0.033	0.478HisMet: 0.478 ± 0.014	1.051HisAsn: 1.051 ± 0.021	1.141HisPro: 1.141 ± 0.023	0.835HisGln: 0.835 ± 0.019	1.21HisArg: 1.21 ± 0.021	1.991HisSer: 1.991 ± 0.058	1.25HisThr: 1.25 ± 0.024	1.259HisVal: 1.259 ± 0.02	0.276HisTrp: 0.276 ± 0.01	0.814HisTyr: 0.814 ± 0.017	0.001HisXaa: 0.001 ± 0.001
Ile	3.594IleAla: 3.594 ± 0.035	0.835IleCys: 0.835 ± 0.019	3.625IleAsp: 3.625 ± 0.041	3.493IleGlu: 3.493 ± 0.042	2.441IlePhe: 2.441 ± 0.033	2.925IleGly: 2.925 ± 0.038	1.207IleHis: 1.207 ± 0.022	3.229IleIle: 3.229 ± 0.041	3.579IleLys: 3.579 ± 0.041	5.44IleLeu: 5.44 ± 0.061	1.218IleMet: 1.218 ± 0.023	3.013IleAsn: 3.013 ± 0.031	3.012IlePro: 3.012 ± 0.036	2.113IleGln: 2.113 ± 0.032	2.617IleArg: 2.617 ± 0.03	4.757IleSer: 4.757 ± 0.048	3.259IleThr: 3.259 ± 0.04	3.72IleVal: 3.72 ± 0.037	0.631IleTrp: 0.631 ± 0.016	1.757IleTyr: 1.757 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.311LysAla: 3.311 ± 0.045	0.802LysCys: 0.802 ± 0.021	3.577LysAsp: 3.577 ± 0.042	4.384LysGlu: 4.384 ± 0.05	2.843LysPhe: 2.843 ± 0.04	2.887LysGly: 2.887 ± 0.033	1.473LysHis: 1.473 ± 0.024	3.916LysIle: 3.916 ± 0.043	5.419LysLys: 5.419 ± 0.077	6.829LysLeu: 6.829 ± 0.061	1.519LysMet: 1.519 ± 0.026	3.524LysAsn: 3.524 ± 0.04	2.757LysPro: 2.757 ± 0.032	2.807LysGln: 2.807 ± 0.036	4.005LysArg: 4.005 ± 0.047	4.766LysSer: 4.766 ± 0.051	3.732LysThr: 3.732 ± 0.041	3.908LysVal: 3.908 ± 0.044	0.751LysTrp: 0.751 ± 0.016	2.43LysTyr: 2.43 ± 0.031	0.001LysXaa: 0.001 ± 0.001
Leu	5.819LeuAla: 5.819 ± 0.056	1.317LeuCys: 1.317 ± 0.021	5.569LeuAsp: 5.569 ± 0.048	6.262LeuGlu: 6.262 ± 0.058	4.122LeuPhe: 4.122 ± 0.047	4.849LeuGly: 4.849 ± 0.045	2.169LeuHis: 2.169 ± 0.031	4.965LeuIle: 4.965 ± 0.051	6.815LeuLys: 6.815 ± 0.063	10.004LeuLeu: 10.004 ± 0.092	1.958LeuMet: 1.958 ± 0.029	5.19LeuAsn: 5.19 ± 0.054	4.735LeuPro: 4.735 ± 0.045	4.688LeuGln: 4.688 ± 0.049	4.928LeuArg: 4.928 ± 0.046	7.891LeuSer: 7.891 ± 0.066	5.345LeuThr: 5.345 ± 0.057	5.734LeuVal: 5.734 ± 0.057	0.976LeuTrp: 0.976 ± 0.02	3.036LeuTyr: 3.036 ± 0.035	0.004LeuXaa: 0.004 ± 0.001
Met	1.495MetAla: 1.495 ± 0.024	0.28MetCys: 0.28 ± 0.011	1.424MetAsp: 1.424 ± 0.023	1.359MetGlu: 1.359 ± 0.024	0.925MetPhe: 0.925 ± 0.017	1.315MetGly: 1.315 ± 0.024	0.367MetHis: 0.367 ± 0.011	1.163MetIle: 1.163 ± 0.022	1.433MetLys: 1.433 ± 0.025	1.939MetLeu: 1.939 ± 0.029	0.503MetMet: 0.503 ± 0.015	1.176MetAsn: 1.176 ± 0.023	0.854MetPro: 0.854 ± 0.02	0.755MetGln: 0.755 ± 0.019	0.978MetArg: 0.978 ± 0.018	1.988MetSer: 1.988 ± 0.032	1.206MetThr: 1.206 ± 0.025	1.338MetVal: 1.338 ± 0.02	0.215MetTrp: 0.215 ± 0.009	0.619MetTyr: 0.619 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.142AsnAla: 3.142 ± 0.038	0.643AsnCys: 0.643 ± 0.018	3.276AsnAsp: 3.276 ± 0.043	3.496AsnGlu: 3.496 ± 0.041	2.251AsnPhe: 2.251 ± 0.029	3.38AsnGly: 3.38 ± 0.041	1.001AsnHis: 1.001 ± 0.019	3.16AsnIle: 3.16 ± 0.04	3.398AsnLys: 3.398 ± 0.039	4.593AsnLeu: 4.593 ± 0.05	1.153AsnMet: 1.153 ± 0.022	3.234AsnAsn: 3.234 ± 0.061	2.307AsnPro: 2.307 ± 0.034	1.68AsnGln: 1.68 ± 0.027	2.23AsnArg: 2.23 ± 0.03	4.594AsnSer: 4.594 ± 0.056	3.115AsnThr: 3.115 ± 0.042	3.432AsnVal: 3.432 ± 0.036	0.604AsnTrp: 0.604 ± 0.016	1.742AsnTyr: 1.742 ± 0.027	0.001AsnXaa: 0.001 ± 0.001
Pro	3.068ProAla: 3.068 ± 0.043	0.409ProCys: 0.409 ± 0.014	2.293ProAsp: 2.293 ± 0.026	3.046ProGlu: 3.046 ± 0.035	1.891ProPhe: 1.891 ± 0.029	2.328ProGly: 2.328 ± 0.038	1.033ProHis: 1.033 ± 0.022	2.474ProIle: 2.474 ± 0.031	2.614ProLys: 2.614 ± 0.04	4.411ProLeu: 4.411 ± 0.046	0.914ProMet: 0.914 ± 0.021	2.231ProAsn: 2.231 ± 0.03	2.761ProPro: 2.761 ± 0.06	2.269ProGln: 2.269 ± 0.042	2.168ProArg: 2.168 ± 0.033	3.946ProSer: 3.946 ± 0.068	3.044ProThr: 3.044 ± 0.042	3.094ProVal: 3.094 ± 0.035	0.458ProTrp: 0.458 ± 0.013	1.353ProTyr: 1.353 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	2.105GlnAla: 2.105 ± 0.031	0.504GlnCys: 0.504 ± 0.013	2.185GlnAsp: 2.185 ± 0.031	2.731GlnGlu: 2.731 ± 0.039	1.935GlnPhe: 1.935 ± 0.03	2.057GlnGly: 2.057 ± 0.038	0.968GlnHis: 0.968 ± 0.018	2.232GlnIle: 2.232 ± 0.032	2.446GlnLys: 2.446 ± 0.032	4.613GlnLeu: 4.613 ± 0.045	0.968GlnMet: 0.968 ± 0.019	2.108GlnAsn: 2.108 ± 0.038	1.816GlnPro: 1.816 ± 0.04	3.222GlnGln: 3.222 ± 0.093	2.463GlnArg: 2.463 ± 0.036	2.967GlnSer: 2.967 ± 0.034	2.221GlnThr: 2.221 ± 0.029	2.245GlnVal: 2.245 ± 0.029	0.494GlnTrp: 0.494 ± 0.014	1.436GlnTyr: 1.436 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	2.996ArgAla: 2.996 ± 0.04	0.7ArgCys: 0.7 ± 0.016	3.171ArgAsp: 3.171 ± 0.037	3.346ArgGlu: 3.346 ± 0.04	2.074ArgPhe: 2.074 ± 0.028	2.839ArgGly: 2.839 ± 0.043	1.147ArgHis: 1.147 ± 0.023	2.778ArgIle: 2.778 ± 0.031	3.469ArgLys: 3.469 ± 0.043	4.475ArgLeu: 4.475 ± 0.052	1.044ArgMet: 1.044 ± 0.018	2.541ArgAsn: 2.541 ± 0.035	1.906ArgPro: 1.906 ± 0.032	2.009ArgGln: 2.009 ± 0.032	3.457ArgArg: 3.457 ± 0.051	3.853ArgSer: 3.853 ± 0.041	2.775ArgThr: 2.775 ± 0.038	2.835ArgVal: 2.835 ± 0.03	0.545ArgTrp: 0.545 ± 0.015	1.692ArgTyr: 1.692 ± 0.03	0.002ArgXaa: 0.002 ± 0.001
Ser	5.095SerAla: 5.095 ± 0.058	0.945SerCys: 0.945 ± 0.021	4.366SerAsp: 4.366 ± 0.048	4.489SerGlu: 4.489 ± 0.044	3.418SerPhe: 3.418 ± 0.041	5.0SerGly: 5.0 ± 0.143	1.807SerHis: 1.807 ± 0.03	4.658SerIle: 4.658 ± 0.044	5.431SerLys: 5.431 ± 0.053	7.986SerLeu: 7.986 ± 0.066	1.804SerMet: 1.804 ± 0.028	4.543SerAsn: 4.543 ± 0.057	3.808SerPro: 3.808 ± 0.049	3.182SerGln: 3.182 ± 0.04	3.943SerArg: 3.943 ± 0.044	8.819SerSer: 8.819 ± 0.165	5.522SerThr: 5.522 ± 0.066	5.213SerVal: 5.213 ± 0.055	0.778SerTrp: 0.778 ± 0.017	2.333SerTyr: 2.333 ± 0.033	0.001SerXaa: 0.001 ± 0.001
Thr	4.359ThrAla: 4.359 ± 0.048	0.673ThrCys: 0.673 ± 0.016	3.217ThrAsp: 3.217 ± 0.04	3.511ThrGlu: 3.511 ± 0.041	2.453ThrPhe: 2.453 ± 0.036	3.771ThrGly: 3.771 ± 0.047	1.279ThrHis: 1.279 ± 0.022	3.219ThrIle: 3.219 ± 0.039	3.772ThrLys: 3.772 ± 0.038	5.772ThrLeu: 5.772 ± 0.049	1.191ThrMet: 1.191 ± 0.021	3.047ThrAsn: 3.047 ± 0.032	3.432ThrPro: 3.432 ± 0.044	2.176ThrGln: 2.176 ± 0.029	2.732ThrArg: 2.732 ± 0.036	5.02ThrSer: 5.02 ± 0.062	4.492ThrThr: 4.492 ± 0.079	4.334ThrVal: 4.334 ± 0.042	0.572ThrTrp: 0.572 ± 0.018	1.586ThrTyr: 1.586 ± 0.025	0.001ThrXaa: 0.001 ± 0.001
Val	4.328ValAla: 4.328 ± 0.046	0.895ValCys: 0.895 ± 0.019	3.898ValAsp: 3.898 ± 0.04	3.997ValGlu: 3.997 ± 0.044	2.687ValPhe: 2.687 ± 0.036	3.461ValGly: 3.461 ± 0.041	1.357ValHis: 1.357 ± 0.022	3.379ValIle: 3.379 ± 0.038	3.928ValLys: 3.928 ± 0.038	5.988ValLeu: 5.988 ± 0.06	1.28ValMet: 1.28 ± 0.024	2.982ValAsn: 2.982 ± 0.04	3.348ValPro: 3.348 ± 0.041	2.442ValGln: 2.442 ± 0.033	2.946ValArg: 2.946 ± 0.035	5.413ValSer: 5.413 ± 0.053	3.792ValThr: 3.792 ± 0.037	4.36ValVal: 4.36 ± 0.051	0.661ValTrp: 0.661 ± 0.017	2.074ValTyr: 2.074 ± 0.029	0.001ValXaa: 0.001 ± 0.001
Trp	0.6TrpAla: 0.6 ± 0.017	0.234TrpCys: 0.234 ± 0.01	0.749TrpAsp: 0.749 ± 0.018	0.647TrpGlu: 0.647 ± 0.017	0.504TrpPhe: 0.504 ± 0.015	0.588TrpGly: 0.588 ± 0.018	0.235TrpHis: 0.235 ± 0.009	0.603TrpIle: 0.603 ± 0.016	0.76TrpLys: 0.76 ± 0.017	0.942TrpLeu: 0.942 ± 0.021	0.236TrpMet: 0.236 ± 0.009	0.615TrpAsn: 0.615 ± 0.017	0.305TrpPro: 0.305 ± 0.009	0.396TrpGln: 0.396 ± 0.012	0.605TrpArg: 0.605 ± 0.015	0.834TrpSer: 0.834 ± 0.02	0.569TrpThr: 0.569 ± 0.017	0.642TrpVal: 0.642 ± 0.017	0.158TrpTrp: 0.158 ± 0.008	0.392TrpTyr: 0.392 ± 0.012	0.001TrpXaa: 0.001 ± 0.001
Tyr	1.771TyrAla: 1.771 ± 0.025	0.526TyrCys: 0.526 ± 0.014	1.952TyrAsp: 1.952 ± 0.029	1.836TyrGlu: 1.836 ± 0.03	1.554TyrPhe: 1.554 ± 0.027	1.87TyrGly: 1.87 ± 0.03	0.781TyrHis: 0.781 ± 0.018	1.873TyrIle: 1.873 ± 0.03	1.95TyrLys: 1.95 ± 0.028	3.306TyrLeu: 3.306 ± 0.037	0.722TyrMet: 0.722 ± 0.018	1.779TyrAsn: 1.779 ± 0.027	1.311TyrPro: 1.311 ± 0.022	1.286TyrGln: 1.286 ± 0.02	1.609TyrArg: 1.609 ± 0.024	2.477TyrSer: 2.477 ± 0.033	1.823TyrThr: 1.823 ± 0.026	1.999TyrVal: 1.999 ± 0.029	0.398TyrTrp: 0.398 ± 0.012	1.296TyrTyr: 1.296 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.002XaaAsp: 0.002 ± 0.001	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.002XaaIle: 0.002 ± 0.001	0.002XaaLys: 0.002 ± 0.001	0.002XaaLeu: 0.002 ± 0.001	0.002XaaMet: 0.002 ± 0.001	0.001XaaAsn: 0.001 ± 0.001	0.0XaaPro: 0.0 ± 0.0	0.001XaaGln: 0.001 ± 0.001	0.001XaaArg: 0.001 ± 0.001	0.002XaaSer: 0.002 ± 0.001	0.001XaaThr: 0.001 ± 0.001	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.002XaaTyr: 0.002 ± 0.001	0.055XaaXaa: 0.055 ± 0.009

Statistics based on 5301 proteins (2648969 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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