Amino acid dipepetide frequency for Gokushovirinae Bog8989_22

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.746AlaAla: 7.746 ± 4.478
0.0AlaCys: 0.0 ± 0.0
6.197AlaAsp: 6.197 ± 2.018
3.098AlaGlu: 3.098 ± 1.204
3.873AlaPhe: 3.873 ± 1.643
6.197AlaGly: 6.197 ± 4.423
1.549AlaHis: 1.549 ± 1.034
5.422AlaIle: 5.422 ± 0.985
2.324AlaLys: 2.324 ± 2.283
5.422AlaLeu: 5.422 ± 2.289
0.775AlaMet: 0.775 ± 0.533
5.422AlaAsn: 5.422 ± 3.249
5.422AlaPro: 5.422 ± 1.528
4.648AlaGln: 4.648 ± 2.398
4.648AlaArg: 4.648 ± 1.818
7.746AlaSer: 7.746 ± 5.621
5.422AlaThr: 5.422 ± 2.729
6.197AlaVal: 6.197 ± 2.38
2.324AlaTrp: 2.324 ± 0.931
2.324AlaTyr: 2.324 ± 0.725
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.775CysAsp: 0.775 ± 0.533
0.775CysGlu: 0.775 ± 1.121
0.775CysPhe: 0.775 ± 0.705
1.549CysGly: 1.549 ± 1.151
0.0CysHis: 0.0 ± 0.0
0.775CysIle: 0.775 ± 0.533
0.0CysLys: 0.0 ± 0.0
3.098CysLeu: 3.098 ± 2.961
0.0CysMet: 0.0 ± 0.0
1.549CysAsn: 1.549 ± 0.76
0.0CysPro: 0.0 ± 0.0
0.775CysGln: 0.775 ± 0.705
0.0CysArg: 0.0 ± 0.0
0.775CysSer: 0.775 ± 1.138
1.549CysThr: 1.549 ± 1.722
0.775CysVal: 0.775 ± 1.138
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.648AspAla: 4.648 ± 1.516
2.324AspCys: 2.324 ± 1.73
2.324AspAsp: 2.324 ± 2.292
2.324AspGlu: 2.324 ± 1.262
2.324AspPhe: 2.324 ± 1.01
1.549AspGly: 1.549 ± 1.061
2.324AspHis: 2.324 ± 1.107
2.324AspIle: 2.324 ± 2.359
2.324AspLys: 2.324 ± 1.476
3.873AspLeu: 3.873 ± 1.068
2.324AspMet: 2.324 ± 0.732
2.324AspAsn: 2.324 ± 1.01
1.549AspPro: 1.549 ± 1.488
2.324AspGln: 2.324 ± 1.262
3.098AspArg: 3.098 ± 2.057
7.746AspSer: 7.746 ± 2.668
3.098AspThr: 3.098 ± 1.331
1.549AspVal: 1.549 ± 0.799
1.549AspTrp: 1.549 ± 0.799
6.197AspTyr: 6.197 ± 2.568
0.0AspXaa: 0.0 ± 0.0
Glu
5.422GluAla: 5.422 ± 2.147
0.775GluCys: 0.775 ± 1.107
1.549GluAsp: 1.549 ± 1.273
0.775GluGlu: 0.775 ± 0.533
2.324GluPhe: 2.324 ± 1.262
2.324GluGly: 2.324 ± 1.256
1.549GluHis: 1.549 ± 0.76
1.549GluIle: 1.549 ± 1.065
0.775GluLys: 0.775 ± 1.138
2.324GluLeu: 2.324 ± 1.366
0.0GluMet: 0.0 ± 0.0
1.549GluAsn: 1.549 ± 1.065
1.549GluPro: 1.549 ± 1.065
3.098GluGln: 3.098 ± 1.562
3.873GluArg: 3.873 ± 1.294
1.549GluSer: 1.549 ± 0.76
2.324GluThr: 2.324 ± 2.359
1.549GluVal: 1.549 ± 0.799
0.775GluTrp: 0.775 ± 0.705
3.098GluTyr: 3.098 ± 1.186
0.0GluXaa: 0.0 ± 0.0
Phe
3.098PheAla: 3.098 ± 1.716
0.775PheCys: 0.775 ± 1.121
3.873PheAsp: 3.873 ± 1.521
0.775PheGlu: 0.775 ± 1.121
2.324PhePhe: 2.324 ± 1.167
3.098PheGly: 3.098 ± 1.621
2.324PheHis: 2.324 ± 1.347
6.197PheIle: 6.197 ± 2.357
3.098PheLys: 3.098 ± 2.133
4.648PheLeu: 4.648 ± 2.2
1.549PheMet: 1.549 ± 1.119
1.549PheAsn: 1.549 ± 0.76
1.549PhePro: 1.549 ± 1.119
1.549PheGln: 1.549 ± 1.034
3.098PheArg: 3.098 ± 2.122
3.098PheSer: 3.098 ± 1.002
3.873PheThr: 3.873 ± 2.056
2.324PheVal: 2.324 ± 1.467
0.775PheTrp: 0.775 ± 0.533
1.549PheTyr: 1.549 ± 1.312
0.0PheXaa: 0.0 ± 0.0
Gly
6.971GlyAla: 6.971 ± 4.234
0.0GlyCys: 0.0 ± 0.0
3.873GlyAsp: 3.873 ± 1.663
4.648GlyGlu: 4.648 ± 1.703
1.549GlyPhe: 1.549 ± 1.065
5.422GlyGly: 5.422 ± 2.422
0.775GlyHis: 0.775 ± 0.533
2.324GlyIle: 2.324 ± 1.366
3.098GlyLys: 3.098 ± 1.602
9.295GlyLeu: 9.295 ± 2.948
1.549GlyMet: 1.549 ± 1.065
1.549GlyAsn: 1.549 ± 1.022
2.324GlyPro: 2.324 ± 1.232
0.775GlyGln: 0.775 ± 0.533
2.324GlyArg: 2.324 ± 1.467
6.971GlySer: 6.971 ± 1.249
5.422GlyThr: 5.422 ± 2.729
5.422GlyVal: 5.422 ± 2.499
0.0GlyTrp: 0.0 ± 0.0
3.873GlyTyr: 3.873 ± 2.663
0.0GlyXaa: 0.0 ± 0.0
His
0.775HisAla: 0.775 ± 0.705
0.775HisCys: 0.775 ± 0.533
0.775HisAsp: 0.775 ± 0.533
0.775HisGlu: 0.775 ± 0.705
1.549HisPhe: 1.549 ± 1.273
3.098HisGly: 3.098 ± 1.562
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.549HisLys: 1.549 ± 1.119
1.549HisLeu: 1.549 ± 0.76
0.0HisMet: 0.0 ± 0.0
1.549HisAsn: 1.549 ± 1.462
3.098HisPro: 3.098 ± 1.175
0.775HisGln: 0.775 ± 0.533
0.0HisArg: 0.0 ± 0.0
1.549HisSer: 1.549 ± 0.76
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.549HisTrp: 1.549 ± 1.065
0.775HisTyr: 0.775 ± 0.705
0.0HisXaa: 0.0 ± 0.0
Ile
4.648IleAla: 4.648 ± 1.516
0.0IleCys: 0.0 ± 0.0
3.873IleAsp: 3.873 ± 1.331
0.775IleGlu: 0.775 ± 0.533
1.549IlePhe: 1.549 ± 1.065
3.873IleGly: 3.873 ± 1.219
0.0IleHis: 0.0 ± 0.0
1.549IleIle: 1.549 ± 0.76
3.098IleLys: 3.098 ± 2.309
5.422IleLeu: 5.422 ± 1.428
0.0IleMet: 0.0 ± 0.921
3.098IleAsn: 3.098 ± 1.599
3.098IlePro: 3.098 ± 1.52
0.775IleGln: 0.775 ± 1.107
3.098IleArg: 3.098 ± 1.133
3.873IleSer: 3.873 ± 1.948
2.324IleThr: 2.324 ± 1.01
0.775IleVal: 0.775 ± 0.533
0.775IleTrp: 0.775 ± 0.705
6.197IleTyr: 6.197 ± 2.135
0.0IleXaa: 0.0 ± 0.0
Lys
5.422LysAla: 5.422 ± 1.778
0.0LysCys: 0.0 ± 0.0
2.324LysAsp: 2.324 ± 1.467
0.775LysGlu: 0.775 ± 0.989
1.549LysPhe: 1.549 ± 1.061
2.324LysGly: 2.324 ± 0.725
0.0LysHis: 0.0 ± 0.0
0.775LysIle: 0.775 ± 0.533
3.873LysLys: 3.873 ± 1.799
4.648LysLeu: 4.648 ± 1.241
0.775LysMet: 0.775 ± 0.705
0.775LysAsn: 0.775 ± 0.989
2.324LysPro: 2.324 ± 2.176
0.0LysGln: 0.0 ± 0.0
3.098LysArg: 3.098 ± 1.382
2.324LysSer: 2.324 ± 0.725
2.324LysThr: 2.324 ± 1.256
3.098LysVal: 3.098 ± 3.217
0.0LysTrp: 0.0 ± 0.0
3.873LysTyr: 3.873 ± 3.526
0.0LysXaa: 0.0 ± 0.0
Leu
6.197LeuAla: 6.197 ± 5.247
0.775LeuCys: 0.775 ± 1.138
3.098LeuAsp: 3.098 ± 1.382
2.324LeuGlu: 2.324 ± 1.107
5.422LeuPhe: 5.422 ± 2.17
8.521LeuGly: 8.521 ± 2.526
0.0LeuHis: 0.0 ± 0.0
5.422LeuIle: 5.422 ± 1.794
4.648LeuLys: 4.648 ± 3.372
6.197LeuLeu: 6.197 ± 1.834
3.098LeuMet: 3.098 ± 1.19
3.098LeuAsn: 3.098 ± 2.201
10.07LeuPro: 10.07 ± 3.388
2.324LeuGln: 2.324 ± 1.107
5.422LeuArg: 5.422 ± 2.564
11.619LeuSer: 11.619 ± 1.627
3.873LeuThr: 3.873 ± 2.095
4.648LeuVal: 4.648 ± 2.345
1.549LeuTrp: 1.549 ± 0.799
6.971LeuTyr: 6.971 ± 1.319
0.0LeuXaa: 0.0 ± 0.0
Met
2.324MetAla: 2.324 ± 1.718
0.775MetCys: 0.775 ± 0.705
0.775MetAsp: 0.775 ± 0.533
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.549MetGly: 1.549 ± 0.799
0.775MetHis: 0.775 ± 0.705
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.324MetLeu: 2.324 ± 2.098
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.775MetGln: 0.775 ± 0.989
3.098MetArg: 3.098 ± 1.123
4.648MetSer: 4.648 ± 0.923
0.775MetThr: 0.775 ± 0.533
0.775MetVal: 0.775 ± 1.121
0.0MetTrp: 0.0 ± 0.0
0.775MetTyr: 0.775 ± 0.533
0.0MetXaa: 0.0 ± 0.0
Asn
3.098AsnAla: 3.098 ± 1.599
1.549AsnCys: 1.549 ± 1.312
3.098AsnAsp: 3.098 ± 1.416
0.0AsnGlu: 0.0 ± 0.0
2.324AsnPhe: 2.324 ± 0.931
3.098AsnGly: 3.098 ± 1.559
0.775AsnHis: 0.775 ± 0.705
0.775AsnIle: 0.775 ± 1.107
2.324AsnLys: 2.324 ± 0.931
6.197AsnLeu: 6.197 ± 1.998
0.0AsnMet: 0.0 ± 0.0
3.873AsnAsn: 3.873 ± 1.652
4.648AsnPro: 4.648 ± 1.817
3.098AsnGln: 3.098 ± 2.201
5.422AsnArg: 5.422 ± 2.746
1.549AsnSer: 1.549 ± 1.979
3.873AsnThr: 3.873 ± 0.999
0.0AsnVal: 0.0 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.549ProAla: 1.549 ± 1.119
0.0ProCys: 0.0 ± 0.0
3.873ProAsp: 3.873 ± 1.25
4.648ProGlu: 4.648 ± 1.911
3.098ProPhe: 3.098 ± 1.511
4.648ProGly: 4.648 ± 2.06
2.324ProHis: 2.324 ± 1.188
3.098ProIle: 3.098 ± 1.599
3.098ProLys: 3.098 ± 1.179
9.295ProLeu: 9.295 ± 2.583
2.324ProMet: 2.324 ± 1.565
2.324ProAsn: 2.324 ± 1.347
3.098ProPro: 3.098 ± 1.52
2.324ProGln: 2.324 ± 1.262
3.098ProArg: 3.098 ± 1.133
6.197ProSer: 6.197 ± 3.236
6.197ProThr: 6.197 ± 2.531
2.324ProVal: 2.324 ± 1.347
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.873GlnAla: 3.873 ± 1.353
0.775GlnCys: 0.775 ± 1.107
1.549GlnAsp: 1.549 ± 1.065
6.197GlnGlu: 6.197 ± 2.531
3.098GlnPhe: 3.098 ± 1.133
3.098GlnGly: 3.098 ± 1.562
0.775GlnHis: 0.775 ± 0.533
3.098GlnIle: 3.098 ± 1.52
0.775GlnLys: 0.775 ± 0.533
3.873GlnLeu: 3.873 ± 1.521
0.775GlnMet: 0.775 ± 0.989
1.549GlnAsn: 1.549 ± 0.799
1.549GlnPro: 1.549 ± 1.462
2.324GlnGln: 2.324 ± 0.931
2.324GlnArg: 2.324 ± 0.725
0.775GlnSer: 0.775 ± 0.989
3.873GlnThr: 3.873 ± 2.075
1.549GlnVal: 1.549 ± 1.061
0.0GlnTrp: 0.0 ± 0.0
1.549GlnTyr: 1.549 ± 0.799
0.0GlnXaa: 0.0 ± 0.0
Arg
4.648ArgAla: 4.648 ± 1.695
0.775ArgCys: 0.775 ± 1.138
5.422ArgAsp: 5.422 ± 2.316
1.549ArgGlu: 1.549 ± 1.034
3.098ArgPhe: 3.098 ± 1.167
0.775ArgGly: 0.775 ± 0.533
0.775ArgHis: 0.775 ± 0.533
3.873ArgIle: 3.873 ± 1.531
2.324ArgLys: 2.324 ± 1.366
6.971ArgLeu: 6.971 ± 1.718
1.549ArgMet: 1.549 ± 0.799
1.549ArgAsn: 1.549 ± 1.497
5.422ArgPro: 5.422 ± 3.015
3.098ArgGln: 3.098 ± 1.559
2.324ArgArg: 2.324 ± 1.555
4.648ArgSer: 4.648 ± 2.016
0.775ArgThr: 0.775 ± 0.533
2.324ArgVal: 2.324 ± 1.01
0.0ArgTrp: 0.0 ± 0.0
3.873ArgTyr: 3.873 ± 2.095
0.0ArgXaa: 0.0 ± 0.0
Ser
16.266SerAla: 16.266 ± 9.76
0.0SerCys: 0.0 ± 0.0
5.422SerAsp: 5.422 ± 1.366
1.549SerGlu: 1.549 ± 1.022
5.422SerPhe: 5.422 ± 3.155
6.197SerGly: 6.197 ± 1.482
0.775SerHis: 0.775 ± 0.705
5.422SerIle: 5.422 ± 1.244
0.775SerLys: 0.775 ± 1.107
5.422SerLeu: 5.422 ± 2.021
0.0SerMet: 0.0 ± 0.0
5.422SerAsn: 5.422 ± 0.963
7.746SerPro: 7.746 ± 1.349
3.873SerGln: 3.873 ± 0.999
2.324SerArg: 2.324 ± 1.366
4.648SerSer: 4.648 ± 1.141
3.098SerThr: 3.098 ± 1.716
6.971SerVal: 6.971 ± 2.442
0.775SerTrp: 0.775 ± 0.989
1.549SerTyr: 1.549 ± 1.151
0.0SerXaa: 0.0 ± 0.0
Thr
4.648ThrAla: 4.648 ± 1.71
0.775ThrCys: 0.775 ± 0.533
0.775ThrAsp: 0.775 ± 0.533
2.324ThrGlu: 2.324 ± 1.167
5.422ThrPhe: 5.422 ± 1.736
4.648ThrGly: 4.648 ± 2.325
3.098ThrHis: 3.098 ± 1.498
3.098ThrIle: 3.098 ± 1.498
3.098ThrLys: 3.098 ± 1.599
5.422ThrLeu: 5.422 ± 2.564
2.324ThrMet: 2.324 ± 1.571
2.324ThrAsn: 2.324 ± 1.232
4.648ThrPro: 4.648 ± 2.082
3.098ThrGln: 3.098 ± 2.13
3.098ThrArg: 3.098 ± 1.002
6.197ThrSer: 6.197 ± 2.513
3.098ThrThr: 3.098 ± 0.741
0.775ThrVal: 0.775 ± 1.107
0.0ThrTrp: 0.0 ± 0.0
2.324ThrTyr: 2.324 ± 1.188
0.0ThrXaa: 0.0 ± 0.0
Val
2.324ValAla: 2.324 ± 0.725
1.549ValCys: 1.549 ± 1.022
3.098ValAsp: 3.098 ± 1.382
3.098ValGlu: 3.098 ± 1.809
1.549ValPhe: 1.549 ± 1.671
1.549ValGly: 1.549 ± 0.799
0.0ValHis: 0.0 ± 0.0
2.324ValIle: 2.324 ± 1.476
2.324ValLys: 2.324 ± 1.467
4.648ValLeu: 4.648 ± 2.628
0.775ValMet: 0.775 ± 0.533
3.098ValAsn: 3.098 ± 1.64
3.873ValPro: 3.873 ± 1.864
0.775ValGln: 0.775 ± 0.533
1.549ValArg: 1.549 ± 1.151
4.648ValSer: 4.648 ± 1.744
3.098ValThr: 3.098 ± 1.179
2.324ValVal: 2.324 ± 2.098
0.0ValTrp: 0.0 ± 0.0
2.324ValTyr: 2.324 ± 1.01
0.0ValXaa: 0.0 ± 0.0
Trp
0.775TrpAla: 0.775 ± 0.533
0.0TrpCys: 0.0 ± 0.0
0.775TrpAsp: 0.775 ± 0.989
0.775TrpGlu: 0.775 ± 0.533
0.775TrpPhe: 0.775 ± 0.533
2.324TrpGly: 2.324 ± 0.725
0.775TrpHis: 0.775 ± 0.533
0.775TrpIle: 0.775 ± 0.705
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.775TrpGln: 0.775 ± 0.989
0.0TrpArg: 0.0 ± 0.0
0.775TrpSer: 0.775 ± 0.989
0.775TrpThr: 0.775 ± 0.533
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.775TrpTyr: 0.775 ± 0.533
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.324TyrAla: 2.324 ± 1.347
1.549TyrCys: 1.549 ± 1.273
4.648TyrAsp: 4.648 ± 2.161
1.549TyrGlu: 1.549 ± 1.034
3.098TyrPhe: 3.098 ± 1.52
2.324TyrGly: 2.324 ± 1.366
1.549TyrHis: 1.549 ± 1.273
0.775TyrIle: 0.775 ± 0.705
0.775TyrLys: 0.775 ± 0.533
4.648TyrLeu: 4.648 ± 2.048
0.775TyrMet: 0.775 ± 0.705
3.098TyrAsn: 3.098 ± 0.741
1.549TyrPro: 1.549 ± 1.065
6.197TyrGln: 6.197 ± 1.924
3.873TyrArg: 3.873 ± 1.353
2.324TyrSer: 2.324 ± 1.366
5.422TyrThr: 5.422 ± 1.978
1.549TyrVal: 1.549 ± 0.76
0.0TyrTrp: 0.0 ± 0.0
3.873TyrTyr: 3.873 ± 1.799
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1292 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski